2011 Fiscal Year Final Research Report
Development of the molecular target therapy for the cytokine receptor for suppression of rejection after the lung transplantation
| Project/Area Number |
21791323
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Thoracic surgery
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| Research Institution | Osaka University |
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Principal Investigator |
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| Project Period (FY) |
2009 – 2011
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| Keywords | 呼吸器外科学 |
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| Research Abstract |
IL-6 production increased in local area, but not in peripheral, in allografts of the mouse BO model, and IL-17 production also locally increased without an alteration in the proportion of peripheral Th17 cells while the level of peripheral Treg decrease d. In addition, IL-6 blocking may suppress BO formation.
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[Journal Article] Lung function early after lung transplantation is correlated with the frequency of regulatory T cells2012
Author(s)
Nakagiri T, Warnecke G, Avsar M, Thissen S, Kruse B, Kuhn C, Ziehme P, Knofel AK, Madrahimov N, Okumura M, Sawa Y, Gottlieb J, Simon AR, Haverich A, Struber M
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Journal Title
Surg Today
Volume: 42(3)
Pages: 250-8
Peer Reviewed
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