2010 Fiscal Year Final Research Report
The mechanism of ERK activation via Gonadotrophin receptor activation on ovarian surface epithelial cells
| Project/Area Number |
21791541
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Gunma Institute of Public Health and Environmental Sciences |
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Principal Investigator |
HIRAKAWA Takashi Gunma Institute of Public Health and Environmental Sciences, 研究企画係, 研究員 (80375534)
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| Project Period (FY) |
2009 – 2010
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| Keywords | FSHレセプター / LHレセプター / ゴナドトロピン / 卵巣癌 |
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| Research Abstract |
The expression of Gonadotrophin receptors mRNA and protein were confirmed in OSE-29 cells, derived from ovarian surface epithelial cells. The activation of ERK were observed in the presence of Gonadotrophins in dose-dependent manner. MEK inhibitor, U0126 inhibited the activation of ERK via Gonadotrophin receptor activation.
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Research Products
(1 results)
