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2010 Fiscal Year Final Research Report

Development of Diagnostic Device for Corneal Impairment

Research Project

  • PDF
Project/Area Number 21791692
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Ophthalmology
Research InstitutionNagasaki University

Principal Investigator

UEMATSU Masafumi  Nagasaki University, 病院, 助教 (30380843)

Project Period (FY) 2009 – 2010
Keywords角膜 / バリア機能 / 角膜上皮障害 / 塩化ベンザルコニウム / 毒性試験
Research Abstract

A novel diagnostic device for corneal impairment was developed and manufactured, which is applied for an international patent. Measurement of corneal impairment was succeeded using the device. Furthermore, corneal toxicity due to an eyedrop preservative was able to be evaluated.

  • Research Products

    (5 results)

All 2011 2010 2009 Other

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (2 results) Remarks (1 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Influence of alkyl chain length of benzalkonium chloride on acute corneal epithelial toxicity2010

    • Author(s)
      Uematsu M, Kumagami T, Shimoda K, et al
    • Journal Title

      Cornea 29(11)

      Pages: 1296-1301

    • Peer Reviewed
  • [Presentation] A novel in vivo corneal trans-epithelial electrical resistance measurement device Association for Research and Vision and Ophthalmology2011

    • Author(s)
      Uematsu M, Tanaka Y, Sekine S, et al
    • Organizer
      2011 Annual Meeting
    • Place of Presentation
      アメリカ合衆国
    • Year and Date
      20110500
  • [Presentation] ラタノプロスト製剤による角膜バリア機能の変化2011

    • Author(s)
      上松聖典、手嶋無限、市丸哲郎, ら
    • Organizer
      第115回日本眼科学会総会
    • Place of Presentation
      東京
    • Year and Date
      20110500
  • [Remarks] ホームページ等w

  • [Patent(Industrial Property Rights)] 角膜経上皮電気抵抗値の測定方法( Method of Measuring Electrical Resistance Value of Corneal Trans-Epithelium )2009

    • Inventor(s)
      上松聖典、北岡隆、西田幸二, ら
    • Industrial Property Rights Holder
      長崎大学, 東北大学
    • Industrial Property Number
      09717554(EPC) 12/921,069 (アメリカ)特願2010-501917(日本)
    • Filing Date
      2009-03-03

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Published: 2012-02-13   Modified: 2016-04-21  

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