2010 Fiscal Year Final Research Report
Development of hyposensitization therapy applying the recombinant oral bacteria secreting the allergen of hey fever.
| Project/Area Number |
21791798
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Morphological basic dentistry
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| Research Institution | Nihon University |
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Principal Investigator |
KUWAHARAN Oriko (篠崎 紀子) Nihon University, 松戸歯学部, 講師 (90287665)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 口腔細菌学 / アレルギー |
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| Research Abstract |
In this application, i) "Construction of recombinant Streptococcus anginosus strain which can express stabilizing the recombinant allergen of hay fever caused by cedar pollen" and ii) "Colonization of the recombinant S. anginosus, and the induction of immune response mechanism against allergen of hay fever caused by cedar pollen which secreted from recombinant bacteria using the laboratory animal" were examined.
The aim i) was accomplished, but the aim ii) was underway.
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