2011 Fiscal Year Final Research Report
Development of the crude drug combination denture adhesive with improvement saliva secretion effect
| Project/Area Number |
21791899
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Prosthetic dentistry
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| Research Institution | Tohoku University |
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Principal Investigator |
HONG Guang 東北大学, 大学院・歯学研究科, 助教 (70363083)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 義歯安定剤 / 口腔乾燥症 / 生薬成分 / AQP5 |
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| Research Abstract |
This research aimed at development of the crude drug combination denture adhesive with improvement saliva secretion effect. The significant differences were found among different materials in initial viscocity and adhesive strength of denture adhesive. The values of adhesive strength increased after immersing significantly in each material. Sericin can improved the surface wattability of materials. And the crude drug influenced distribution of AQP5 in salivary duct membrane of parotid positively. The results was suggest that the development of the crude drug combination denture adhesive with improvement saliva secretion effect is possible.
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