2010 Fiscal Year Final Research Report
Research of a novel hard-tissue biodegradable adhesive as a drug delivery carrier.
Project/Area Number |
21800034
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Research Category |
Grant-in-Aid for Research Activity Start-up
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Allocation Type | Single-year Grants |
Research Field |
Biomedical engineering/Biological material science
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Research Institution | Okayama University |
Principal Investigator |
SUGIMOTO Yoshihisa Okayama University, 岡山大学病院, 助教 (80423309)
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Project Period (FY) |
2009 – 2010
|
Keywords | 骨セメント / 生体吸収性 / ドラッグデリバリー / 抗生剤 / 抗癌剤 / リン酸化多糖 |
Research Abstract |
A bioadhesive that can be bonded to hard tissue such as bone and tooth, is highly needed for hard-tissue repair in orthopaedic medicine and dentistry. We developed a novel hard-tissue biodegradable adhesive on basis of phosphorylated pullulan. In this study, we examined the property of phosphorylated pullulan bioadhesive as a drug delivery carrier. As a result, phosphorylated pullulan bioadhesive appears to be an ideal material as a drug delivery carrier.
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