2010 Fiscal Year Final Research Report
Real-time monitoring of single biomolecular interaction under microfluidic control
Project/Area Number |
21810012
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Research Category |
Grant-in-Aid for Research Activity Start-up
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Allocation Type | Single-year Grants |
Research Field |
Nanomaterials/Nanobioscience
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Research Institution | Nagoya University |
Principal Investigator |
ONOSHIMA Daisuke Nagoya University, 工学研究科, 研究員 (40510219)
|
Project Period (FY) |
2009 – 2010
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Keywords | 1分子計測(SMD) / マイクロ・ナノデバイス / ナノバイオ / 生物物理 / 生体分子 |
Research Abstract |
Single-molecule, real-time intermolecular interaction analysis was achieved by microfluidic control. The method enabled tracking and analysis of biomolecules in a physiologically natural state. Further applications of our method will provide new understanding of molecular mechanisms by which DNA and protein perform their diverse biological functions in cells.
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