2010 Fiscal Year Final Research Report
Evaluation of Drug Delivery System Using Intravital Real-Time Confocal Laser Scanninng Microscopy
| Project/Area Number |
21890051
|
|---|
| Research Category |
Grant-in-Aid for Research Activity Start-up
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Applied pharmacology
|
|---|
| Research Institution | The University of Tokyo |
|---|
Principal Investigator |
MATSUMOTO Yu The University of Tokyo, 大学院・医学系研究科, 特任研究員 (80548553)
|
|---|
| Project Period (FY) |
2009 – 2010
|
| Keywords | in vivoイメージング / ドラッグデリバリーシステム / ナノデバイス / 共焦点顕微鏡 / 生体内薬物動態 |
|---|
| Research Abstract |
Intravital real-time confocal laser scanning microscopy was developed based on a Nikon A1R fast-scanning confocal laser scanning microscope. Modification of the microscope, custom-designed mouse stage, anesthetic machine, and surgical stereomicroscope was integrated and optimized for intravital imaging.
|
-
-
-
-
[Journal Article] Direct and Instantaneous Observation of Intravenously Injected Substances Using Intravital Confocal Micro-Videography2010
Author(s)
Matsumoto Y., Nomoto T., Cabral H., Matsumoto Y., Watanabe S., Christie R.J., Miyata K., Oba M., Ogura T., Yamasaki Y., Nishiyama N., Yamasoba T., Kataoka K.
-
Journal Title
Biomed.Opt.Express 1(4)
Pages: 1209-1216
Peer Reviewed
-
-
-
-
-
-
[Presentation] A Novel Light-responsive Polymeric Micelle Nanocarrier Possessing Two Compartments for the Dual Delivery System2011
Author(s)
Takahiro Nomoto, Shigeto Fukushima, Michiaki Kumagai, Kanjiro Miyata, Yu Matsumoto, Makoto Oba, Woo-dong Jang, Nobuhiro Nishiyama, Kazunori Kataoka
Organizer
International Conference on Biomaterials Science 2011
Place of Presentation
Tsukuba International Congress Center, Tsukuba, Ibaraki, Japan
Year and Date
2011-03-16
-
[Presentation] Supramolecular Nano-Devices for siRNA Delivery2011
Author(s)
R.James Christie, Kanjiro Miyata, Shigeto Fukushima, Yu Matsumoto, Nobuhiro Nishiyama, Kazunori Kataoka
Organizer
FIRST International Symposium Medical Innovation of 21st Century "Challenge for the State of the Art Medical System Driven by Nanobiotechnology"
Place of Presentation
Hitotsubashi Memorial Hall, Chiyoda-ku, Tokyo, Japan
Year and Date
2011-01-18
-
[Presentation] Development of Light-responsive Gene Delivery System Applying a Functionally Compartmentalized Nano Device2011
Author(s)
Takahiro Nomoto, Shigeto Fukushima, Michiaki Kumagai, Kanjiro Miyata, Yu Matsumoto, Makoto Oba, Nobuhiro Nishiyama, Kazunori Kataoka
Organizer
FIRST International Symposium Medical Innovation of 21st Century "Challenge for the State of the Art Medical System Driven by Nanobiotechnology"
Place of Presentation
Hitotsubashi Memorial Hall, Chiyoda-ku, Tokyo, Japan
Year and Date
2011-01-16
-
-
-
-
-
[Presentation] Enhanced Antitumor Activity of Proteasome Inhibitor MG132-loaded Polymeric Micelle Drug Carriers, Analyzed by In Vivo Real-Time Confocal Microangiography2010
Author(s)
Yoko Matsumoto, Yu Matsumoto, Yuichiro Miyamoto, Horacio Cabral, Nobuhiro Nishiyama, Shunsuke Nakagawa, Tetsu Yano, Yuji Taketani, Kazunori Kataoka
Organizer
The Third International NanoBio Conference
Place of Presentation
ETH Zurich, Zurich, Switzerland
Year and Date
20100824-20100827
-
-
-
-
-
-
-
-
-
-
[Presentation] Intravital Real-Time Confocal Microangiography2010
Author(s)
Yu Matsumoto, Takahiro Nomoto, Horacio Cabral, Kanjiro Miyata, Makoto Oba, R.James Christie, Sumiyo Watanabe, Yoko Matsumoto, Tadayoshi Ogura, Yuichi Yamasaki, Nobuhiro Nishiyama, Tatsuya Yamasoba, Kazunori Kataoka
Organizer
The Third International NanoBio Conference
Place of Presentation
ETH Zurich, Zurich, Switzerland
Year and Date
2010-08-27
-
-
-
-
-
-
-
-
-
-
[Remarks] ホームページ等
-
-
-
-
-
-
