2023 Fiscal Year Final Research Report
Development of An Implantable Electrical Stimulation Device towards Reconstructing Functional Motions
| Project/Area Number |
21H01290
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Review Section |
Basic Section 20020:Robotics and intelligent system-related
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| Research Institution | Nagoya University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
徳武 克浩 名古屋大学, 医学部附属病院, 助教 (90822289)
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| Project Period (FY) |
2021-04-01 – 2024-03-31
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| Keywords | 機能的電気刺激 / 機能的運動再建 / 埋込デバイス / 無線給電 / 神経刺激装置 |
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| Outline of Final Research Achievements |
This study conducted reconstruction of motor function by peripheral nerve stimulation. We proposed a method to control limb movements by independently stimulating multiple peripheral nerves from a single device. We promoted research on reconstructing walking locomotion in rats using a multi-channel nerve stimulation system synchronized with voluntary movements. We have studied a bidirectional wireless communication function using only a pair of coils, which enables bidirectional wireless communication by transmitting myoelectric information measured in the body to the outside and transmitting information on nerve stimulation intensity based on that information to the inside of the body. Furthermore, we have fabricated a new neurostimulation device that allows for fine-tuning important neurostimulation parameters, such as stimulation current value, stimulation frequency, stimulation pulse duration, and waveform.
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| Free Research Field |
マイクロ・ナノメカトロニクス
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| Academic Significance and Societal Importance of the Research Achievements |
本研究で得られた成果は、新たな治療法の開発が望まれている下位運動ニューロン障害に対する新たな治療法の展開において重要な要素技術であり、本研究成果を基盤技術として研究を発展させることで四肢の運動障害に苦しむ多くの患者に対して新たな運動再建技術を提供できるものである。また、本技術は運動再建だけでなく内分泌系の制御など神経系の働きを体外から精密にコントロール可能とするものであり、応用先としては運動障害だけでなく疼痛や免疫系など様々な分野への発展が見込まれ、その社会的インパクトは非常に大きいと考えられる。
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