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2023 Fiscal Year Final Research Report

The application to the elucidation of pathology and the treatment of DLB focusing the gender difference

Research Project

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Project/Area Number 21K07549
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 52030:Psychiatry-related
Research InstitutionSapporo Medical University

Principal Investigator

Kobayashi Seiju  札幌医科大学, 医学部, 研究員 (50569035)

Co-Investigator(Kenkyū-buntansha) 橋本 恵理  札幌医科大学, 医学部, 准教授 (30301401)
鵜飼 渉  札幌医科大学, 医療人育成センター, 准教授 (40381256)
相馬 仁  札幌医科大学, 医療人育成センター, 教授 (70226702)
Project Period (FY) 2021-04-01 – 2024-03-31
Keywords認知症 / 性差 / レビー小体型認知症
Outline of Final Research Achievements

Using a common questionnaire, we investigated basic attributes (age, gender) and clinical evaluation using various evaluation scales (MMSE, HDS-R, CDR) for patients with dementia including DLB. Regarding the presence or absence of BPSD, the symptoms were divided into 10 symptoms using the NPI as an index: delusions, hallucinations, excitement, depression, anxiety, euphoria, idleness, disinhibition, irritability, and abnormal behavior. We examined the frequency of BPSD by symptom and also analyzed it by gender.
Understanding the characteristics of BPSD due to gender differences seems to be useful information when considering support systems for men and women.

Free Research Field

老年精神医学

Academic Significance and Societal Importance of the Research Achievements

DLBを含め認知症の性差による、症状の違い、BPSD の特徴を把握しておくことは,男女別にも支援体制を考える上で有用な情報であると思われる.今後の高齢化社会の進展を鑑み,認知症医療においてBPSD症状に対する診療や,男女を含めた個々のニーズに合った介護支援等について,さらに検討していきたい.

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Published: 2025-01-30  

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