2023 Fiscal Year Final Research Report
Construction of 3D dynamic myocardial phantom and standardization guideline for the accuracy management of cardiac function evaluation
| Project/Area Number |
21K07615
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Review Section |
Basic Section 52040:Radiological sciences-related
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| Research Institution | Kanazawa University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
澁谷 孝行 金沢大学, 保健学系, 助教 (80762509)
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| Project Period (FY) |
2021-04-01 – 2024-03-31
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| Keywords | 心臓動態ファントム / 心電図同期心筋SPECT / 心機能 / 精度管理 / 標準化 |
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| Outline of Final Research Achievements |
This study was to establish a bottom line based on LV function data. The seven types of SPECT or SPECT/CT system were used. The radionuclide was used Tc-99m, and the LV function analysis of the SPECT data were processed using quantitative gated SPECT(QGS). The phantom was set up using the regular model with an EDV of 80.0 mL, ESV of 40.0 mL, LVEF of 50%. The LV function was calculated using EDV, ESV, LVEF, and stroke volume/wall motion (SV/WM). The criteria of bottom line were determined from LV function analyzed by ECG-gated SPECT data with identical conditions in various institutions. The mean and SD of the LV functions was 60.4±1.5 mL for EDV, 29.3±0.8 mL for ESV, 51.7±1.38% for LVEF, and 4.7±0.28 mL/mm for SV/WM. Each bottom line was 58 mL for EDV, 28 mL for ESV, 49-54 % for LVEF, and 4.2 mL/mm for SV/WM. The criteria of bottom line were determined from LV function analyzed by ECG-gated SPECT data with identical conditions in various institutions.
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| Free Research Field |
心臓核医学
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| Academic Significance and Societal Importance of the Research Achievements |
心電図同期心筋SPECTは心筋血流や心機能評価が不可欠な存在となっているが，機能画像や心機能指標値の精度管理を目的とした心臓動態ファントムはなかった。本研究のコンセプトは心電図同期心筋SPECTの最低限のレベルの確保と問題のある機能画像や指標値であれば，フローチャート形式で指導もしくは改善項目を提示する。そこで，心電図同期心筋SPECTによる機能画像や心機能指標値の精度管理および標準化を目的に，三次元心臓動態ファントムの構築と改良，精度管理の確立および心電図同期心筋SPECT撮像の技術的な標準化ガイドラインを構築した。波及効果として，データを構築する技師や医師の技術水準の向上が期待できる。
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