2023 Fiscal Year Final Research Report
Effects of exercise training on plasticity of gastrointestinal tract function and intestinal environment
Project/Area Number |
21K11447
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Review Section |
Basic Section 59020:Sports sciences-related
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Research Institution | Yamagata Prefectural Yonezawa University of Nutrition Sciences |
Principal Investigator |
Kato Morimasa 山形県立米沢栄養大学, 健康栄養学部, 教授 (20399330)
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Project Period (FY) |
2021-04-01 – 2024-03-31
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Keywords | レジスタンストレーニング / 脱トレーニング / 可塑性 / 腸内環境 |
Outline of Final Research Achievements |
The present study is to examine the hypothesis that the gastrointestinal tract function and intestinal environment have the same physical plasticity as skeletal muscles, respiratory and cardiovascular systems, metabolic and endocrine systems, and brain function, and to elucidate the adaptation mechanism of the gastrointestinal tract function and intestinal environment through exercise. We examined the effects of exercise training and de-training periods using resistance training in humans and mice. As a result, intestinal microbiota and metabolites in feces were found to be altered in relation to changes in body composition associated with training. For future studies, we will consider effective supplements and training indexes for resistance training that take account of these effects on the intestinal environment.
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Free Research Field |
運動生理学
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Academic Significance and Societal Importance of the Research Achievements |
本研究は、運動による消化管機能及び腸内環境がどのように適応するかの解明であり、健常成人及びマウスによるレジスタンストレーニングからトレーニング期間だけでなく脱トレーニング期間も設定して運動トレーニングの影響を検討した。本研究からレジスタンストレーニングによる身体機能の変化には、腸内環境の可塑性も関連することが示唆された。この知見は運動トレーニングによる腸内環境も考慮した栄養摂取条件の探索やより効果的な筋機能改善トレーニング法の確立に意義がある。
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