Creation of Pyridylidenes Based on Rearomatization

2022 Fiscal Year Final Research Report

• Project/Area Number: 21K14607
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 33010:Structural organic chemistry and physical organic chemistry-related
• Research Institution: University of Tsukuba
• Principal Investigator: Morisako Shogo 筑波大学, 数理物質系, 助教 (70874840)
• Project Period (FY): 2021-04-01 – 2023-03-31
• Keywords: カルベン / シリレン / ゲルミレン / 低配位化学種 / 芳香族化合物 / 小分子活性化 / 典型元素 / 分子触媒

Outline of Final Research Achievements

Establishment of a method to replace toxic and/or rare transition metal catalysts with abundant elements is one of the important issues to realize a sustainable society. Low-coordinated species of group 14 elements bearing high reactivity and moderate stability are expected to show catalytic activity. In this study, we attempted to create new low-coordinated species of group 14 elements with aromaticity as a stabilizing factor. In the process of constructing the molecular backbone, we developed a method to provide heteroatom-substituted π-electron systems with a Si-H bond activation. We also succeeded in synthesizing and isolating a new germylene with a cyclic π-electron framework, which is different from acyclic germylenes in its electronic structure.

Free Research Field

有機元素化学，有機金属化学

Academic Significance and Societal Importance of the Research Achievements

π電子骨格に組み込まれた低配位14族元素化学種においても，種々の結合を切断できるほどの高い反応性を有していることが明らかとなり，高反応性化学種の新たな分子設計指針の一つとなりえる成果であり，ここに学術的な意義がある。
本研究で開発した，環状π電子骨格含有低配位14族化学種の発生を鍵とするスピロ化合物の合成手法は，従来法では困難であったかさ高い置換基を有するスピロ化合物の合成を可能とし，機能性材料開発への応用が期待される。ここに社会的な意義がある。