Aromatic Oligomer Micelles with High Uptake and Responsive Abilities

2022 Fiscal Year Final Research Report

• Project/Area Number: 21K18951
• Research Category: Grant-in-Aid for Challenging Research (Exploratory)
• Allocation Type: Multi-year Fund
• Review Section: Medium-sized Section 33:Organic chemistry and related fields
• Research Institution: Tokyo Institute of Technology
• Principal Investigator: Yoshizawa Michito 東京工業大学, 科学技術創成研究院, 教授 (70372399)
• Project Period (FY): 2021-07-09 – 2023-03-31
• Keywords: 芳香環ミセル / オリゴマー / 分子捕捉

Outline of Final Research Achievements

We succeeded in the preparation of novel aromatic oligomer micelles in water, through the cross-linking of bent amphiphilic molecules bearing polyaromatic panels and in the development of a molecular technology for the creation of new materials in water, by the use of the aromatic oligomer micelles with excellent self-assembly stability, molecular capture ability, and encapsulation-response function. Actually, in this work, amphiphilic oligomers with multiple bent polyaromatic panels were newly designed and synthesized. By their self-assembly in water, the quantitative formation of aromatic oligomer micelles with high assembly stability and wide molecular uptake ability was achieved. Furthermore, unique optical properties were observed by efficient encapsulation of functional molecules and materials such as oligothiophenes.

Free Research Field

超分子化学

Academic Significance and Societal Importance of the Research Achievements

水を媒体とした新材料の創製や新機能の開拓は、科学技術産業の更なる発展に重要である。水中の材料創製と機能開拓で最大の課題は、対象とする材料の「水溶化」である。大部分の材料は水に不溶であるため、直接的な官能基化が必須である。しかしながら、この方法の短所は、親水基導入のために複雑な合成ステップが必要で、導入された親水基による材料機能の低下リスクが発生し、官能基化後に元の構造を再生できない。本研究では、優れた捕捉能と応答能を有する芳香環オリゴマーミセルの創製に成功し、オリゴチオフェンなどの機能材料の高効率な水溶化とそれら特異な光物性などを解明した。