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2013 Fiscal Year Annual Research Report

がん研究分野の特性等を踏まえた支援活動

Research Project

Project Areaがん研究分野の特性等を踏まえた支援活動
Project/Area Number 221S0001
Research InstitutionThe University of Tokyo

Principal Investigator

今井 浩三  東京大学, 医科学研究所, 特任教授 (60117603)

Co-Investigator(Kenkyū-buntansha) 中村 卓郎  公益財団法人がん研究会, がん研究所 発がん研究部, 副所長 (00180373)
山村 研一  熊本大学, 生命資源研究・支援センター, 教授 (90115197)
八尾 良司  公益財団法人がん研究会, がん研究所 細胞生物部, 主任研究員 (80291095)
高野 洋志  公益財団法人がん研究会, がん研究所 細胞生物部, 研究員 (00241555)
高倉 彰  公益財団法人実験動物中央研究所, ICLASモニタリングセンター, 部長 (60167484)
中潟 直己  熊本大学, 生命資源研究・支援センター, 教授 (30159058)
加藤 秀樹  浜松医科大学, 医学部附属動物実験施設, 准教授 (30142053)
豊國 伸哉  名古屋大学, 医学系研究科, 教授 (90252460)
鰐渕 英機  大阪市立大学, 大学院医学研究科, 教授 (90220970)
小川 勝洋  旭川医科大学, 医学部, 名誉教授 (50045514)
渋谷 淳  東京農工大学, (連合)農学研究科(研究院), 教授 (20311392)
今井田 克己  香川大学, 医学部, 教授 (90160043)
二口 充  名古屋市立大学, 大学院医学研究科, 准教授 (60275120)
神田 浩明  公益財団法人がん研究会, がん研究所 病理部, 主任研究員 (90260067)
田中 英夫  愛知県がんセンター(研究所), 疫学・予防部, 部長 (60470168)
若井 建志  名古屋大学, 医学系研究科, 准教授 (50270989)
三上 春夫  千葉県がんセンター(研究所), がん予防センター・がん登録・予防疫学研究部, 部長 (10332355)
鈴木 貞夫  名古屋市立大学, 大学院医学研究科, 教授 (20226509)
喜多 義邦  滋賀医科大学, 医学部, 助教 (30147524)
渡辺 能行  京都府立医科大学, 医学(系)研究科(研究院), 教授 (00191809)
有澤 孝吉  徳島大学, 大学院ヘルスバイオサイエンス研究部(医学系), 教授 (30203384)
田中 恵太郎  佐賀大学, 医学部, 教授 (50217022)
嶽崎 俊郎  鹿児島大学, 医歯(薬)学総合研究科, 教授 (50227013)
古庄 憲浩  九州大学, 医学研究院, 准教授 (10346786)
樋野 興夫  順天堂大学, 医学部, 教授 (90127910)
玉腰 暁子  北海道大学, 医学(系)研究科(研究院), 教授 (90236737)
江口 英孝  埼玉医科大学, 医学部, 准教授 (00260232)
久保 充明  独立行政法人理化学研究所, 統合生命医科学研究センター, 副センター長 (30442958)
内藤 真理子  名古屋大学, 医学(系)研究科(研究院), 准教授 (10378010)
田原 栄俊  広島大学, 大学院医歯薬保健学研究院(薬), 教授 (00271065)
椙村 春彦  浜松医科大学, 医学部, 教授 (00196742)
永田 知里  岐阜大学, 大学院医学系研究科, 教授 (30283295)
大中 佳三  九州大学, 医学研究院, 講師 (30325518)
津金 昌一郎  独立行政法人国立がん研究センター, がん予防・検診研究センター, センター長 (40179982)
高山 哲治  徳島大学, 大学院ヘルスバイオサイエンス研究部(医学系), 教授 (10284994)
赤座 英之  東京大学, 先端科学技術研究センター, 特任教授 (70010486)
高橋 悟  日本大学, 医学部, 教授 (50197141)
舛森 直哉  札幌医科大学, 医学部, 准教授 (20295356)
内藤 誠二  九州大学, 医学研究院, 教授 (40164107)
並木 幹夫  金沢大学, 医学系, 教授 (70155985)
藤本 清秀  奈良県立医科大学, 医学部, 教授 (50264867)
藤岡 知昭  岩手医科大学, 医学部, 教授 (80173409)
堀江 重郎  順天堂大学, 医学(系)研究科(研究院), 教授 (40190243)
森 満  札幌医科大学, 医学部, 教授 (50175634)
森脇 久隆  岐阜大学, 大学院医学系研究科, 教授 (50174470)
神奈木 真理  東京医科歯科大学, 医歯(薬)学総合研究科, 教授 (80202034)
石田 高司  名古屋市立大学, 大学院医学研究科, 准教授 (80405183)
松岡 雅雄  京都大学, ウイルス研究所, 教授 (10244138)
山岡 昇司  東京医科歯科大学, 医歯(薬)学総合研究科, 教授 (90263160)
田中 勇悦  琉球大学, 医学(系)研究科(研究院), 教授 (30163588)
渡邉 俊樹  東京大学, 大学院新領域創成科学研究科, 教授 (30182934)
醍醐 弥太郎  滋賀医科大学, 医学部, 教授 (30345029)
高橋 隆  名古屋大学, 大学院医学系研究科, 教授 (50231395)
宮城 洋平  地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), がん分子病態学部, 部長 (00254194)
旦 慎吾  公益財団法人がん研究会, がん化学療法センター 分子薬理部, 主任研究員 (70332202)
上原 至雅  岩手医科大学, 薬学部, 教授 (50160213)
吉田 稔  独立行政法人理化学研究所, 吉田化学遺伝学研究室, 主任研究員 (80191617)
井本 正哉  慶應義塾大学, 理工学部(矢上), 教授 (60213253)
清宮 啓之  公益財団法人がん研究会, がん化学療法センター 分子生物治療研究部, 部長 (50280623)
深澤 秀輔  国立感染症研究所, 生物活性物質部, 室長 (10218878)
川田 学  公益財団法人微生物化学研究会, 微生物化学研究所 沼津支所, 主席研究員 (20300808)
長田 裕之  独立行政法人理化学研究所, ケミカルバイオロジー研究領域, 領域長 (80160836)
松浦 正明  公益財団法人がん研究会, がん研究所 がんゲノム研究部, 部長 (40173794)
馬島 哲夫  公益財団法人がん研究会, がん化学療法センター 分子生物治療研究部, 研究員 (30311228)
水上 民夫  長浜バイオ大学, バイオサイエンス学部, 教授 (80367896)
時野 隆至  札幌医科大学, 医学部, 教授 (40202197)
鈴木 拓  札幌医科大学, 医学部, 教授 (20381254)
Keywords若手支援 / 国際交流 / 遺伝子改変マウス / 病理形態学 / ゲノムコーホート研究 / 個別化がん予防 / ATL発症予防 / アカデミア創薬
Research Abstract

総括支援:公開シンポジウム、ワークショップ(日仏、日韓、がん若手:95名参加・発表)、青少年市民公開講座開催。がん研究読本③をネット出版。
個体レベル支援:ES分与等18、Tg作製15、キメラ作製48、F1 29、ES細胞操作20、Flp/Creによるアレル変換19、CRIPR/Cas9関連4、モニタリング(微生物770、遺伝1770)、ジェノタイピング818、保存・クリーニング50系統、病理形態学26を支援、ワークショップ開催。
がん疫学・予防支援:9万9千名の研究者提供生体試料を用いた研究支援。テロメア長測定支援5、aberrant crypt fociをバイオマーカーとした大腸癌予防介入試験支援6、肥満と肝発癌関連実験モデル作成等がん予防への研究支援。HTLV-I研究支援:HTLV-1研究支援として、患者検体の免疫解析、プロウイルス量測定、抗ATLワクチン療法やCCR4抗体治療研究の後方支援、HTLV-1関連単クロン抗体の製造管理・供与、患者登録システムJSPFAD 8500検体の維持運営・検体供与を行なった。
臨床診断研究支援:組織・FFPE872、血清・DNA877のがん試料収集、8研究者に計2486を提供。腎、卵巣がん402からなる組織アレイ構築。肺がん等の15件の診断法検証支援で論文13編に貢献。組織バンク、技術支援と公開講演会開催。
化学療法基盤支援:寄託化合物の分子標的阻害活性評価、化合物ライブラリーの整備・配付。各種薬剤作用関連の遺伝子発現変動、がん新薬開発情報等をDB化、公開。シンポジウム(がん新薬開発合同、食品薬学)開催。
ゲノム・エピゲノム支援:腫瘍組織・FFPE検体等の409がん関連遺伝子の変異について10研究者から271検体を解析。腫瘍組織・正常対照部・細胞株のDNAメチル化解析を実施。3研究者から47遺伝子のプライマーを設計し、238検体を解析。

Current Status of Research Progress
Current Status of Research Progress

1: Research has progressed more than it was originally planned.

Reason

各支援活動とも、計画に沿って順調に支援を続けているが、以下の活動では計画以上の進展を示した。若手研究者支援では、「がん特定領域研究」時代以来の継続による積極的取組が功を奏し、がん研究を初めとする医学生物学系においてリーダーとなる人材が輩出するようになってきた。また、国際交流活動ではフランス、韓国、ドイツとの相互交流がより活発となり、共同研究や人材交流が一層盛んになっている。広報活動として、がん研究の現状を一般にわかりやすく解説したネット出版物「がん研究読本」も好評を得ている。また、市民公開講演会も実施し、本事業の成果を公表し、200人近くの市民が熱心に聴講した。
一方、研究者のネットワーク構築を背景として、臨床診断研究支援を初めとするがん研究者への支援から世界をリードするがん研究の論文成果が着実に挙げられている。さらに、当初の計画では大きな部分を占めてはいなかったが、脳・ゲノム支援活動との連携促進による生命科学系3分野としての活動が開始され、特にモデル動物に関する情報交換が盛んになったことから、今後一層の支援効率化が期待出来る状況になった。平成24年度から追加されたゲノム・エピゲノム解析支援も活動が進展し、患者サンプルのみならずモデル動物の解析態勢も整備されてきている。

Strategy for Future Research Activity

平成22~25年度の支援活動をより強固に継続するとともに、若手研究者を中心として科研費採択課題に対する積極的な支援を行う。がん若手研究シンポジウム及び、日仏・日独・日韓の2国間がんワークショップは本年も開催するが、今後の発展を見据えて育成・交流の成果を挙げたい。個体レベルの研究支援においては、CRISPR/Cas9に代表される最新テクノロジーを利用したモデル動物開発を進めるとともに、病理形態解析に細胞初期化を専門とする研究分担者を加えて、がんと再生・幹細胞研究の連携を推進する。また、個体レベルのがん研究ワークショップを引き続き開催して、支援の成果を公表する。がん疫学・予防支援では、コホート研究で得られた試料のがん研究への利用を倫理面での評価を行いながら推進する。臨床診断研究支援では、プロテオーム解析や組織アレイのさらなる充実化を図り、がん研究者へのヒト検体を用いた解析を支援することで、世界レベルの研究成果の増産を目指す。
化学療法基盤支援活動では、がん研究分野以外への支援も視野に入れた化合物の評価・スクリーニングを進める。がんゲノム・エピゲノム解析支援活動では、上述のように支援体制が整備されたので、ヒト検体・モデル動物検体に対する、遺伝子変異パネルの解析を推進する。
また、生命科学系3分野間の連携を一層促進し、今後の自然科学系の具体的な推進策を立案する。特に、本支援活動が、ボトムアップ支援と最先端技術を開発と一体化した体制を構築するよう検討を進める。

  • Research Products

    (281 results)

All 2014 2013 Other

All Journal Article (147 results) (of which Peer Reviewed: 147 results) Presentation (115 results) (of which Invited: 22 results) Book (16 results) Remarks (3 results)

  • [Journal Article] Mesenchymal stem cells cancel azoxymethane-induced tumor initiation.2014

    • Author(s)
      Nasuno M, Arimura Y, Nagaishi K, Isshiki H, Onodera K, Nakagaki S, Watanabe S, Idogawa M, Yamashita K, Naishiro Y, Adachi Y, Suzuki H, Fujimiya M, Imai K, Shinomura Y.
    • Journal Title

      STEM CELLS

      Volume: 32(4) Pages: 913-925

    • DOI

      10.1002/stem.1594.

    • Peer Reviewed
  • [Journal Article] Low serum level of high-sensitivity C-reactive protein in a Japanese subject with MODY3.2014

    • Author(s)
      Ohki T, Utsu Y, Morita S, Karim M.F., Sato Y, Yoshizawa T, Yamamura K, Yamada K, Kasayama S, Yamagata K.
    • Journal Title

      J. Diabetes Invest.

      Volume: in press. Pages: -

    • Peer Reviewed
  • [Journal Article] Autophagy regulation in the pancreatic acinar cells is independent of epidermal growth factor receptor signaling.2014

    • Author(s)
      Ozaki, N., Fukuchi, Y., Tomiyoshi, S., Uehara1, H., Ida, S., Wang, J., Kimi Araki, K., Sibilia, M., Baba, H., and Yamamura, K., and Ohmuraya, M.
    • Journal Title

      Biochem. Biophysic. Res. Comm.

      Volume: in press. Pages: -

    • Peer Reviewed
  • [Journal Article] mTORC1 controls the cell cycle of the earliest T-lineage-committed cells and its inactivation eradicates acute lymphoblastic T-cell leukemia in mice.2014

    • Author(s)
      Hoshii, T., Kasada, A., Hatakeyama, N., Ohtani,M., Tadokoro, Y., Naka, K., Ikenoue, T., Ikawa, T., Kawamoto, H., Araki, K., Yamamura, K., Matsuda, S. and Hirao, A.
    • Journal Title

      Proc. Natl. Acad. Sci. USA.

      Volume: in press. Pages: -

    • Peer Reviewed
  • [Journal Article] Rescue In Vitro Fertilization Method for Legacy Stock of Frozen Mouse Sperm.2014

    • Author(s)
      Nakagata, N., Takeo, T., Fukumoto, K., Haruguchi, Y., Kondo, T., Takeshita, Y., Nakamuta, Y., Umeno, T. and Tsuchiyama, S.
    • Journal Title

      J Reprod Dev

      Volume: 60 Pages: 167-170

    • Peer Reviewed
  • [Journal Article] Preclinical evaluation of an O(6)-methylguanine-DNA methyltransferase-siRNA/liposome complex administered by convection-enhanced delivery to rat and porcine brains.2014

    • Author(s)
      Tsujiuchi T., Natsume A., Motomura K., Kondo G., Ranjit M., Hachisu R., Sugimura I., Tomita S., Takehara I., Woolley M., Barua N.U., Gill S.S., Bienemann A.S., Yamashita Y., Toyokuni S., Wakabayashi T.
    • Journal Title

      Am J Transl Res. eCollection 2014

      Volume: 6 Pages: 169-78

    • Peer Reviewed
  • [Journal Article] A Novel Transgenic Mouse Model Carrying Human Tribbles Related Protein 3 (TRB3) Gene and Its Site Specific Phenotype.2014

    • Author(s)
      Y. Sakai, K. Fukamachi, M. Futakuchi, I. Miyoshi, H. Tsuda, M. Suzui, H. Hayashi.
    • Journal Title

      Biol. Pharm. Bull.

      Volume: in press. Pages: -

    • Peer Reviewed
  • [Journal Article] Importance of the progesterone receptor (PR) and the epidermal growth factor receptor (EGFR), but not the estrogen receptor (ER), for chemically induced lung carcinogenesis in female A/J mice.2014

    • Author(s)
      Kishi S., Yokohira M., Yamakawa K., Saoo K., Imaida K.
    • Journal Title

      Oncol. Lett.

      Volume: in press Pages: -

    • Peer Reviewed
  • [Journal Article] Cross-boundary Cancer Studies at the University of Tokyo: View from the world of science and reason.2014

    • Author(s)
      Akaza H.
    • Journal Title

      Japanese journal of clinical oncology

      Volume: 44 Suppl 1 Pages: i3-5

    • DOI

      10.1093/jjco/hyt228

    • Peer Reviewed
  • [Journal Article] Cross-boundary cancer studies at the University of Tokyo: Surviving cancer in Asia: introduction.2014

    • Author(s)
      Akaza H, Kawahara N.
    • Journal Title

      Japanese journal of clinical oncology

      Volume: 44 Suppl 1 Pages: i1-2

    • DOI

      10.1093/jjco/hyt231

    • Peer Reviewed
  • [Journal Article] Japanese Cancer Association Meeting UICC International session--what is cost-effectiveness in cancer treatment?2014

    • Author(s)
      Akaza H, Kawahara N, Roh JK et al.
    • Journal Title

      Asian Pacific journal of cancer prevention : APJCP

      Volume: 15 Pages: 3-10

    • DOI

      10.7314/APJCP.2014.15.1.3

    • Peer Reviewed
  • [Journal Article] Associations of dietary patterns with metabolic syndrome and insulin resistance: a cross-sectional study in a Japanese population.2014

    • Author(s)
      Arisawa K, Uemura H, Yamaguchi M et al.
    • Journal Title

      J Med Invest

      Volume: in press Pages: -

    • Peer Reviewed
  • [Journal Article] Associations between hOGG1 Ser326Cys polymorphism and increased body mass index and fasting glucose in the Japanese general population.2014

    • Author(s)
      Hara M, Nakamura K, Nanri H, KIta Y, Suzuki S, Ohnaka K, Mikami H, Kubo M, Tanaka H et al.
    • Journal Title

      Journal of epidemiology / Japan Epidemiological Association

      Volume: in press Pages: -

    • Peer Reviewed
  • [Journal Article] Retrospective analysis of large-scale research screening of construction workers for the early diagnosis of mesothelioma.2014

    • Author(s)
      Hirohashi T, Igarashi K, Abe M, Hino O et al.
    • Journal Title

      Molecular and clinical oncology

      Volume: 2 Pages: 26-30

    • DOI

      10.3892/mco.2013.197

    • Peer Reviewed
  • [Journal Article] GCK, GCKR polymorphisms and risk of chronic kidney disease in Japanese individuals: data from the J-MICC Study.2014

    • Author(s)
      Hishida A, Takashima N, Turin TC, Wakai K, Suzuki S, Mikami H, Ohnaka K, Kubo M, Tanaka H, Kita Y et al.
    • Journal Title

      Journal of nephrology

      Volume: 27 Pages: 143-149

    • DOI

      10.1007/s40620-013-0025-0

    • Peer Reviewed
  • [Journal Article] ERC/mesothelin is expressed in human gastric cancer tissues and cell lines.2014

    • Author(s)
      Ito T, Kajino K, Abe M, Hino O et al.
    • Journal Title

      Oncology reports

      Volume: 31 Pages: 27-33

    • DOI

      10.3892/or.2013.2803

    • Peer Reviewed
  • [Journal Article] Comparison of plasma levels of nutrients-related biomarkers among Japanese populations in Tokyo, Japan, in Sao Paulo, Brazil, and in Hawaii, USA.2014

    • Author(s)
      Iwasaki M, Franke A, Hamada G, Tsugane S et al.
    • Journal Title

      European Journal of Cancer Prevention

      Volume: in press Pages: in press

    • Peer Reviewed
  • [Journal Article] C-ERC/mesothelin provokes lymphatic invasion of colorectal adenocarcinoma.2014

    • Author(s)
      Kawamata F, Homma S, Kamachi H, Hino O et al.
    • Journal Title

      Journal of gastroenterology

      Volume: 49 Pages: 81-92

    • DOI

      10.1007/s00535-013-0773-6

    • Peer Reviewed
  • [Journal Article] ABCG2 dysfunction causes hyperuricemia due to both renal urate underexcretion and renal urate overload.2014

    • Author(s)
      Matsuo H, Nakayama A, Sakiyama M, Wakai K et al.
    • Journal Title

      Scientific reports

      Volume: 4 Pages: 3755

    • DOI

      10.1038/srep03755

    • Peer Reviewed
  • [Journal Article] Plasma amino acid profiles are associated with biomarkers of breast cancer risk in premenopausal Japanese women.2014

    • Author(s)
      Nagata C, Wada K, Tsuji M et al.
    • Journal Title

      Cancer causes & control : CCC

      Volume: 25 Pages: 143-149

    • DOI

      10.1007/s10552-013-0316-8

    • Peer Reviewed
  • [Journal Article] Inverse correlation between serum interleukin-6 and iron levels among Japanese adults: a cross-sectional study.2014

    • Author(s)
      Nakagawa H, Tamura T, Mitsuda Y, Wakai K et al.
    • Journal Title

      BMC hematology

      Volume: 14 Pages: 6

    • DOI

      10.1186/2052-1839-14-6

    • Peer Reviewed
  • [Journal Article] Objectively measured physical activity and inflammatory cytokine levels in middle-aged Japanese people.2014

    • Author(s)
      Nishida Y, Higaki Y, Taguchi N, Tanaka K et al.
    • Journal Title

      Prev Med

      Volume: in press Pages: -

    • DOI

      10.1016/j.ypmed.2014.04.004

    • Peer Reviewed
  • [Journal Article] Biomarkers for predicting the efficacy of anti-epidermal growth factor receptor antibody in the treatment of colorectal cancer.2014

    • Author(s)
      Okada Y, Miyamoto H, Goji T, Takayama T.
    • Journal Title

      Digestion

      Volume: 89 Pages: 18-23

    • DOI

      10.1159/000356202

    • Peer Reviewed
  • [Journal Article] IGKC and FcgammaR genotypes and humoral immunity to HER2 in breast cancer.2014

    • Author(s)
      Pandey JP, Kistner-Griffin E, Black L, Tsugane S et al.
    • Journal Title

      Immunobiology

      Volume: 219 Pages: 113-117

    • DOI

      10.1016/j.imbio.2013.08.005

    • Peer Reviewed
  • [Journal Article] A common variant of leucine-rich repeat-containing 16A (LRRC16A) gene is associated with gout susceptibility.2014

    • Author(s)
      Sakiyama M, Matsuo H, Shimizu S, Wakai K et al.
    • Journal Title

      Human cell

      Volume: 27 Pages: 1-4

    • DOI

      10.1007/s13577-013-0081-8

    • Peer Reviewed
  • [Journal Article] High antitumor activity of pladienolide B and its derivative in gastric cancer.2014

    • Author(s)
      Sato M, Muguruma N, Nakagawa T, Takayama T et al.
    • Journal Title

      Cancer science

      Volume: 105 Pages: 110-116

    • DOI

      10.1111/cas.12317

    • Peer Reviewed
  • [Journal Article] A novel somatic FGFR3 mutation in primary lung cancer.2014

    • Author(s)
      Shinmura K, Kato H, Matsuura S, Sugimura H et al.
    • Journal Title

      Oncology reports

      Volume: 31 Pages: 1219-1224

    • DOI

      10.3892/or.2014.2984

    • Peer Reviewed
  • [Journal Article] TNK2 gene amplification is a novel predictor of a poor prognosis in patients with gastric cancer.2014

    • Author(s)
      Shinmura K, Kiyose S, Nagura K, Sugimura H et al.
    • Journal Title

      Journal of surgical oncology

      Volume: 109 Pages: 189-197

    • DOI

      10.1002/jso.23482

    • Peer Reviewed
  • [Journal Article] Counts of Slackia sp. strain NATTS in intestinal flora are correlated to serum concentrations of equol both in prostate cancer cases and controls in Japanese men.2014

    • Author(s)
      Sugiyama Y, Nagata Y, Fukuta F, Masumori N, Akaza H et al.
    • Journal Title

      J Cancer Prev

      Volume: in press Pages: -

    • Peer Reviewed
  • [Journal Article] Breakages at YWHAE, FAM22A, and FAM22B loci in uterine angiosarcoma: a case report with immunohistochemical and genetic analysis.2014

    • Author(s)
      Suzuki S, Tanioka F, Minato H, Sugimura H et al.
    • Journal Title

      Pathology, research and practice

      Volume: 210 Pages: 130-134

    • DOI

      10.1016/j.prp.2013.09.009

    • Peer Reviewed
  • [Journal Article] An autopsy case of malignant pleural mesothelioma associated with nephrotic syndrome.2014

    • Author(s)
      Suzuki S, Toyoshima M, Nihashi F, Sugimura H et al.
    • Journal Title

      Internal medicine

      Volume: 53 Pages: 243-246

    • DOI

      10.2169/internalmedicine.53.1313

    • Peer Reviewed
  • [Journal Article] Advances in cancer epidemiology in Japan.2014

    • Author(s)
      Tanaka H.
    • Journal Title

      International journal of cancer Journal international du cancer

      Volume: 134 Pages: 747-754

    • DOI

      10.1002/ijc.28519

    • Peer Reviewed
  • [Journal Article] Multicenter phase II study of mogamulizumab (KW-0761), a defucosylated anti-CCR4 antibody, in patients with relapsed peripheral T-cell lymphoma and cutaneous T-cell lymphoma.2014

    • Author(s)
      Ogura M*, Ishida T*, Hatake K, Taniwaki M, Ando K, Tobinai K, Fujimoto K, Yamamoto K, Miyamoto T, Uike N, Tanimoto M, Tsukasaki K, Ishizawa K, Suzumiya J, Inagaki H, Tamura K, Akinaga S, Tomonaga M, Ueda R.
    • Journal Title

      J Clin Oncol,

      Volume: 32(11) Pages: 1157-1163

    • DOI

      10.1200/JCO.2013.52.0924

    • Peer Reviewed
  • [Journal Article] Reactivation of hepatitis B virus in a patient with adult T-cell leukemia-lymphoma receiving the anti-CC chemokine receptor 4 antibody mogamulizumab.2014

    • Author(s)
      Nakano N, Kusumoto S, Tanaka Y, Ishida T, Takeuchi S, Takatsuka Y, Akinaga S, Mizokami M, Ueda R, Utsunomiya A.
    • Journal Title

      Hepatol Res.

      Volume: 44(3) Pages: 354-357

    • DOI

      10.1111/hepr.12117

    • Peer Reviewed
  • [Journal Article] Multimodal Effects of Small Molecule ROCK and LIMK Inhibitors on Mitosis, and Their Implication as Anti-Leukemia Agents.2014

    • Author(s)
      Oku Y, Tareyanagi C, Takaya S, Osaka S, Ujiie H, Yoshida K, Nishiya N, Uehara Y.
    • Journal Title

      PLoS One

      Volume: 9(3) Pages: e92402

    • DOI

      10.1371/journal.pone.0092402

    • Peer Reviewed
  • [Journal Article] A Zebrafish Chemical Suppressor Screening Identifies Small Molecule Inhibitors of the Wnt/β-catenin Pathway.2014

    • Author(s)
      Nishiya N, Oku Y, Kumagai Y, Sato Y, Yamaguchi E, Sasaki A, Shoji M, Ohnishi Y, Okamoto H, Uehara Y.
    • Journal Title

      Chem. Biol.

      Volume: in press. Pages: -

    • DOI

      10.1016/j.chembiol.2014.02.015.

    • Peer Reviewed
  • [Journal Article] Genetically encoded FRET indicators for live-cell imaging of histone acetylation.2014

    • Author(s)
      Sasaki K, Yoshida M.
    • Journal Title

      Methods Mol. Biol.

      Volume: 1071 Pages: 151-161

    • DOI

      10.1007/978-1-62703-622-1_12

    • Peer Reviewed
  • [Journal Article] 5-Lipoxygenase and CysLT1 regulate EGF‐induced cell migration through Tiam1 upregulation and Rac1 activation.2014

    • Author(s)
      Magi S, Takemoto Y, Kobayashi H, Kasamatsu M, Akita T, Tanaka A, Takano K, Tashiro E, Igarashi Y, Imoto M.
    • Journal Title

      Cancer Science.

      Volume: 105 Pages: 290-296

    • DOI

      10.1111/cas.12340

    • Peer Reviewed
  • [Journal Article] Retinoids and rexinoids inhibit hepatitis C virus independently of retinoid receptor signaling.2014

    • Author(s)
      Murakami Y, Fukasawa M, Kaneko Y, Suzuki T, Wakita T, Fukazawa H.
    • Journal Title

      Microbes and Infection

      Volume: 16 Pages: 114-122.

    • DOI

      10.1016/j.micinf.2013.10.016

    • Peer Reviewed
  • [Journal Article] Aberrant methylation of microRNA-34b/c is a predictive marker of metachronous gastric cancer risk.2013

    • Author(s)
      Suzuki R, Yamamoto E, Nojima M, Maruyama R, Yamano HO, Yoshikawa K, Kimura T, Harada T, Ashida M, Niinuma T, Sato A, Nosho K, Yamamoto H, Kai M, Sugai T, Imai K, Suzuki H, Shinomura Y.
    • Journal Title

      J Gastroenterol

      Volume: [Epub ahead of print] Pages: -

    • Peer Reviewed
  • [Journal Article] Methylation of a panel of microRNA genes is a novel biomarker for detection of bladder cancer.2013

    • Author(s)
      Shimizu T, Suzuki H, Nojima M, Kitamura H, Yamamoto E, Maruyama R, Ashida M, Hatahira T, Kai M, Masumori N, Tokino T, Imai K, Tsukamoto T, Toyota M.
    • Journal Title

      Eur Urol

      Volume: 63(6) Pages: 1091-1100

    • DOI

      10.1016/j.eururo.2012.11.030.

    • Peer Reviewed
  • [Journal Article] Association between genomic alterations and metastatic behavior of colorectal cancer identified by array-based comparative genomic hybridization.2013

    • Author(s)
      Sawada T, Yamamoto E, Suzuki H, Nojima M, Maruyama R, Shioi Y, Akasaka R, Kamimae S, Harada T, Ashida M, Kai M, Adachi Y, Yamamoto H, Imai K, Toyota M, Itoh F, Sugai T.
    • Journal Title

      Genes Chromosomes Cancer.

      Volume: 52(2) Pages: 140-149

    • DOI

      10.1002/gcc.22013

    • Peer Reviewed
  • [Journal Article] Report of the Japan Diabetes Society/Japanese Cancer Association joint committee on diabetes and cancer.2013

    • Author(s)
      Kasuga M, Ueki K, Tajima N, Noda M, Ohashi K, Noto H, Goto A, Ogawa W, Sakai R, Tsugane S, Hamajima N, Nakagama H, Tajima K, Miyazono K, Imai K.
    • Journal Title

      Cancer Sci

      Volume: 104(7) Pages: 965-976

    • DOI

      10.1111/cas.12203.

    • Peer Reviewed
  • [Journal Article] PADI4 regulates proliferation of hematopoietic stem/multipotent cells via controlling c-Myc expression.2013

    • Author(s)
      Nakashima, K., Arai, S., Suzuki, A., Nariai, Y., Urano, T., Nakayama, M., Ohara, O., Yamamura, K., Yamamoto, K. and Miyazaki, T.
    • Journal Title

      Nature Comm.

      Volume: 4 Pages: 1836

    • DOI

      10.1038/ncomms2862

    • Peer Reviewed
  • [Journal Article] Obesity-associated autoantibody production requires AIM to retain IgM immune complex on follicular dendritic cells.2013

    • Author(s)
      Arai, A., Morita, K., Maehara, K., Iwamura, Y., Honda, S., Nakashima, K., Kurokawa, J., Mori, M., Motoi, Y., Miyake, K., Yamamura, K., Ohara, O., Shibuya, A., Wakeland, E. K., Li, Q.-Z. and Miyazaki, T.
    • Journal Title

      Cell Report

      Volume: 3 Pages: 1187-1198

    • DOI

      10.1016/j.celrep.2013.03.006

    • Peer Reviewed
  • [Journal Article] Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from MSM/Ms mice.2013

    • Author(s)
      Nakahara, M., Tateyama, H., Araki, M., Nakagata, N., Yamamura, K. and Araki, K.
    • Journal Title

      Mammal Genome

      Volume: 24 Pages: 228-239

    • DOI

      10.1007/s00335-013-9452-4

    • Peer Reviewed
  • [Journal Article] Investigations of motility and fertilization potential in thawed cryopreserved mouse sperm from cold-stored epididymides.2013

    • Author(s)
      Takeo, T., Fukumoto, K., Kondo, T., Haruguchi, Y., Takeshita, Y., Nakamuta, Y., Tsuchiyama, S., Yoshimoto, H., Shimizu, N., Li, MW., Kinchen, K., Vallelunga, J., Lloyd, KC. and Nakagata, N.
    • Journal Title

      Cryobiology.

      Volume: 68(1) Pages: 12-7

    • DOI

      10.1016/j.cryobiol.2013.10.007. Epub 2013 Nov 4.

    • Peer Reviewed
  • [Journal Article] Applications of cryopreserved unfertilized mouse oocytes for in vitro fertilization.2013

    • Author(s)
      Nakagata, N., Takeo, T., Fukumoto, K., Kondo, T., Haruguchi, Y., Takeshita, Y., Nakamuta, Y., Matsunaga, H., Tsuchiyama, S., Ishizuka, Y. and Araki, K.
    • Journal Title

      Cryobiology.

      Volume: 67(2) Pages: 188-92

    • DOI

      10.1016/j.cryobiol.2013.06.011.Epub 2013.

    • Peer Reviewed
  • [Journal Article] Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome.2013

    • Author(s)
      Yoshimoto, S., Loo, TM., Atarashi, K., Kanda, H., Sato, S., Oyadomari, S., Iwakura, Y., Oshima, K., Morita, H., Hattori, M., Honda, K., Ishikawa, Y., Hara, E. and Ohtani N.
    • Journal Title

      Nature

      Volume: 499 Pages: 97-101

    • DOI

      10.1038/nature12347

    • Peer Reviewed
  • [Journal Article] Novel mouse model for Gardner syndrome generated by a large-scale ENU mutagenesis program.2013

    • Author(s)
      Toki, H., Inoue, M., Motegi, H., Minowa, O., Kanda, H., Yamamoto, N., Ikeda, A., Karashima, Y., Matsui, J., Kaneda, H., Miura, I., Suzuki, T., Masuya, H., Wakana, S., Gondo, Y., Shiroishi, T., Akiyama, T., Yao, R. and Noda, T.
    • Journal Title

      Cancer Science

      Volume: 104 Pages: 937-944

    • DOI

      10.1111/cas.12161.

    • Peer Reviewed
  • [Journal Article] Lewis y antigen is expressed in oral squamous cell carcinoma cell lines and tissues, but disappears in the invasive regions leading to the enhanced malignant properties irrespective of sialyl-Lewis x.2013

    • Author(s)
      Hotta H., Hamamura K., Yamashita K,. Shibuya H., Tokuda N., Hashimoto N., Furukawa K., Yamamoto N., Hattori H., Toyokuni S., Ueda M., Furukawa K.
    • Journal Title

      Glycoconj J

      Volume: 30 Pages: 585-597

    • DOI

      10.1007/s10719-012-9458-2.

    • Peer Reviewed
  • [Journal Article] CD146 and IMP3 predict prognosis of asbestos-induced rat mesothelioma.2013

    • Author(s)
      Okazaki Y., Nagai H., Chew S.H., Jiang L., Funahashi S., Tsujimura T. and Toyokuni S.
    • Journal Title

      Cancer Sci

      Volume: 104 Pages: 989-995

    • DOI

      10.1111/cas.12185.

    • Peer Reviewed
  • [Journal Article] Intraperitoneal administration of tangled multiwalled carbon nanotubes of 15 nm in diameter does not induce mesothelial carcinogenesis in rats.2013

    • Author(s)
      Nagai H., Okazaki Y., Chew S.H., Misawa N., Miyata Y., Shinohara N. and Toyokuni S.
    • Journal Title

      Pathol Int

      Volume: 63 Pages: 457-462

    • DOI

      10.1111/pin.12093.

    • Peer Reviewed
  • [Journal Article] Deferasirox induces mesenchymal-epithelial transition in crocidolite-induced mesothelila carcinogenesis in rats.2013

    • Author(s)
      Nagai H., Okazaki Y., Chew S.H., Misawa N., Yasui H. and Toyokuni S.
    • Journal Title

      Cance Prev Res

      Volume: 6 Pages: 1222-30

    • DOI

      10.1158/1940-6207.CAPR-13-0244.

    • Peer Reviewed
  • [Journal Article] A novel reporter rat strain that expresses LacZ upon Cre-mediated recombination.2013

    • Author(s)
      K. Fukamachi, H. Tanaka, Y. Sakai, D.B. Alexander, M. Futakuchi, H. Tsuda, M. Suzui.
    • Journal Title

      Genesis

      Volume: 51 Pages: 268-274

    • DOI

      10.1002/dvg.22371.

    • Peer Reviewed
  • [Journal Article] Promotive effects of cell proliferation and chromosomal instability induced by tribbles-related protein 3 in mouse mammary tumor cells.2013

    • Author(s)
      Y. Sakai, K. Fukamachi, M. Futakuchi, H. Hayashi, M. Suzui.
    • Journal Title

      Oncology reports

      Volume: 30 Pages: 64-70

    • DOI

      10.3892/or.2013.2441.

    • Peer Reviewed
  • [Journal Article] Nanosized zinc oxide particles do not promote DHPN-induced lung carcinogenesis but cause reversible epithelial hyperplasia of terminal bronchioles.2013

    • Author(s)
      J. Xu, M. Futakuchi, D.B. Alexander, K. Fukamachi, T. Numano, M. Suzui, H. Shimizu, T. Omori, J. Kanno, A. Hirose, H. Tsuda.
    • Journal Title

      Archives of toxicology

      Volume: 88 Pages: 65-75

    • DOI

      10.1007/s00204-013-1086-5.

    • Peer Reviewed
  • [Journal Article] Post-natal treatment by a blood-brain-barrier permeable calpain inhibitor, SNJ1945 rescued defective function in lissencephaly.2013

    • Author(s)
      Toba, S., Tamura, Y., Kumamoto, K., Yamada, M., Takao, K., Hattori, S., Miyakawa, T., Kataoka, Y., Azuma, M., Hayasaka, K., Amamoto, M., Tominaga, K., Wynshaw-Boris, A., Wanibuchi, H., Oka, Y., Sato, M., Kato, M., Hirotsune, S.
    • Journal Title

      Sci Rep

      Volume: 3 Pages: 1224

    • DOI

      10.1038/srep01224.

    • Peer Reviewed
  • [Journal Article] MUC5AC protects pancreatic cancer cells from TRAIL-induced death pathways.2013

    • Author(s)
      Hoshi, H., Sawada, T., Uchida, M., Iijima, H., Kimura, K., Hirakawa, K., Wanibuchi, H.
    • Journal Title

      Int J Oncol

      Volume: 42 Pages: 887-893

    • DOI

      10.3892/ijo.2013.1760.

    • Peer Reviewed
  • [Journal Article] Mode of action of ethyl tertiary-butyl ether hepatotumorigenicity in the rat: Evidence for a role of oxidative stress via activation of CAR, PXR and PPAR signaling pathways.2013

    • Author(s)
      Kakehashi, A., Hagiwara, A., Imai, N., Nagano, K., Nishimaki, F., Banton, M., Wei, M., Fukushima, S., Wanibuchi, H.
    • Journal Title

      Toxicol Appl Pharmacol

      Volume: 273 Pages: 390-400

    • DOI

      10.1016/j.taap.2013.09.016.

    • Peer Reviewed
  • [Journal Article] Novel medium-term carcinogenesis model for lung squamous cell carcinoma induced by N-nitroso-tris-chloroethylurea in mice.2013

    • Author(s)
      Tago, Y., Yamano, S., Wei, M., Kakehashi, A., Kitano, M., Fujioka, M., Ishii, N., Wanibuchi, H.
    • Journal Title

      Cancer Sci.

      Volume: 104 Pages: 1560-1566

    • DOI

      10.1111/cas.12289

    • Peer Reviewed
  • [Journal Article] Establishment of a 5-fluorouracil-resistant triple-negative breast cancer cell line.2013

    • Author(s)
      Takahashi, K., Tanaka, M., Inagaki, A., Wanibuchi, H., Izumi, Y., Miura, K., Nagayama, K., Shiota, M., Iwao, H.
    • Journal Title

      Int J Oncol

      Volume: 43 Pages: 1985-1991

    • DOI

      10.3892/ijo.2013.2135.

    • Peer Reviewed
  • [Journal Article] Diphenylarsinic acid, a chemical warfare-related neurotoxicant, promotes liver carcinogenesis via activation of aryl hydrocarbon receptor signaling and consequent induction of oxidative DAN damage in rats.2013

    • Author(s)
      Wei, M., Yamada, T., Yamano, S., Kato, M., Kakehashi, A., Fujioka, M., Tago, Y., Kitano, M., Wanibuchi, H.
    • Journal Title

      Toxicol Appl Pharmacol

      Volume: 273 Pages: 1-9

    • DOI

      10.1016/j.taap.2013.08.022.

    • Peer Reviewed
  • [Journal Article] L-leucine and L-isoleucine enhance growth of BBN-induced urothelial tumors in the rat bladder by modulating expression of amino acid transporters and tumorigenesis-associated genes.2013

    • Author(s)
      Xie, X.L., Kakehashi, A., Wei, M., Yamano, S., Takeshita, M., Yunoki, T., Wanibuchi, H.
    • Journal Title

      Food Chem Toxicol

      Volume: 59 Pages: 137-144

    • DOI

      10.1016/j.fct.2013.05.044.

    • Peer Reviewed
  • [Journal Article] Twenty-one proteins up-regulated in human H-ras oncogene transgenic rat pancreas cancers are up-regulated in human pancreas cancer.2013

    • Author(s)
      Yabushita, S., Fukamachi, K., Kikuchi, F., Ozaki, M., Miyata, K., Sukata, T., Deguchi, Y., Tanaka, H., Kakehashi, A., Kawamura, S., Uwagawa, S., Wanibuchi, H., Suzui, M., Alexander, D.B., Tsuda, H.
    • Journal Title

      Pancreas

      Volume: 42 Pages: 1034-1039

    • DOI

      10.1097/MPA.0b013e3182883624.

    • Peer Reviewed
  • [Journal Article] Napsin A is possibly useful marker to predict the tumorigenic potential of lung bronchiolo-alveolar hyperplasia in F344 rats.2013

    • Author(s)
      Yokohira M., Kishi S., Yamakawa K., Nakano Y., Ninomiya F., Kinouch S., Tanizawa J., Saoo K., Imaida K.
    • Journal Title

      Exp. Toxicol. Pathol.

      Volume: 66 Pages: 117-23

    • DOI

      10.1016/j.etp.2013.11.002. Epub 2013 Dec 2.

    • Peer Reviewed
  • [Journal Article] Gender-dependent effects of gonadectomy on lung carcinogenesis by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in female and male A/J mice.2013

    • Author(s)
      Ninomiya F., Yokohira M., Kishi S., Nakano Y., Yamakawa K., Inoue T., Kuno T., Imaida K.
    • Journal Title

      Oncol Rep

      Volume: 30 Pages: 2632-2638

    • DOI

      10.3892/or.2013.2759. Epub 2013 Oct 1

    • Peer Reviewed
  • [Journal Article] Strain differences in pleural mesothelial cell reactions induced by potassium octatitanate fibers (TISMO) infused directly into the thoracic cavity.2013

    • Author(s)
      Yokohira M., Nakano Y., Yamakawa K., Kishi S., Ninomiya F., Saoo K., Imaida K.
    • Journal Title

      Exp. Toxicol. Pathol.

      Volume: 65(6) Pages: 925-932

    • DOI

      10.1016/j.etp.2013.01.006. Epub 2013 Jan 31.

    • Peer Reviewed
  • [Journal Article] Challenges and outlook for the UICC-Asian Regional Office.2013

    • Author(s)
      Akaza H.
    • Journal Title

      Asian Pacific journal of cancer prevention : APJCP

      Volume: 14 Pages: 4935-4937

    • DOI

      10.7314/APJCP.2013.14.8.4935

    • Peer Reviewed
  • [Journal Article] Union for International Cancer Control International Session: healthcare economics: the significance of the UN Summit non-communicable diseases political declaration in Asia.2013

    • Author(s)
      Akaza H, Kawahara N, Masui T et al.
    • Journal Title

      Cancer science

      Volume: 104 Pages: 773-778

    • DOI

      10.1111/cas.12142

    • Peer Reviewed
  • [Journal Article] CYP1A1, GSTM1, GSTT1 and NQO1 polymorphisms and colorectal adenomas in Japanese men.2013

    • Author(s)
      Hamachi T, Tajima O, Uezono K, Ohnaka K et al.
    • Journal Title

      World journal of gastroenterology : WJG

      Volume: 19 Pages: 4023-4030

    • DOI

      10.3748/wjg.v19.i25.4023

    • Peer Reviewed
  • [Journal Article] Coffee consumption, serum gamma-glutamyltransferase, and glucose tolerance status in middle-aged Japanese men.2013

    • Author(s)
      Hiramatsu T, Tajima O, Uezono K, Ohnaka K et al.
    • Journal Title

      Clinical chemistry and laboratory medicine

      Volume: 51 Pages: 1233-1239

    • DOI

      10.1515/cclm-2012-0700

    • Peer Reviewed
  • [Journal Article] MTHFR, MTR and MTRR polymorphisms and risk of chronic kidney disease in Japanese: cross-sectional data from the J-MICC Study.2013

    • Author(s)
      Hishida A, Okada R, Guang Y, Naito M, Wakai K, Suzuki S, Mikami H, Kubo M, Tanaka H et al.
    • Journal Title

      International urology and nephrology

      Volume: 45 Pages: 1613-1620

    • DOI

      10.1007/s11255-013-0432-0

    • Peer Reviewed
  • [Journal Article] Polymorphisms in genes encoding antioxidant enzymes (SOD2, CAT, GPx, TXNRD, SEPP1, SEP15 and SELS) and risk of chronic kidney disease in Japanese - cross-sectional data from the J-MICC study.2013

    • Author(s)
      Hishida A, Okada R, Naito M, Wakai K, Suzuki S, Mikami H, Arisawa K, KUbo M, Tanaka H et al.
    • Journal Title

      Journal of clinical biochemistry and nutrition

      Volume: 53 Pages: 15-20

    • DOI

      10.3164/jcbn.13-17

    • Peer Reviewed
  • [Journal Article] Polymorphisms in PPAR Genes (PPARD, PPARG, and PPARGC1A) and the Risk of Chronic Kidney Disease in Japanese: Cross-Sectional Data from the J-MICC Study.2013

    • Author(s)
      Hishida A, Wakai K, Naito M, Suzuki S, Mikami H, Ohnaka K, Watanabe Y, Arisawa K, Kubo M, Tanaka H et al.
    • Journal Title

      PPAR research 2013

      Volume: - Pages: 980471

    • DOI

      10.1155/2013/980471

    • Peer Reviewed
  • [Journal Article] Significant interaction between RETN -420 G/G genotype and lower BMI on decreased risk of type 2 diabetes mellitus (T2DM) in Japanese--the J-MICC Study.2013

    • Author(s)
      Hishida A, Wakai K, Okada R, Suzuki S, Mikami H, Kubo M, Tanaka H, Naito M et al.
    • Journal Title

      Endocrine journal

      Volume: 60 Pages: 237-243

    • DOI

      10.1507/endocrj.EJ12-0307

    • Peer Reviewed
  • [Journal Article] Establishment and characterization of a mutagenized cell line exhibiting the 'cell-in-cell' phenotype at a high frequency.2013

    • Author(s)
      Kahyo T, Sugimura H.
    • Journal Title

      Genes to cells : devoted to molecular & cellular mechanisms

      Volume: 18 Pages: 1042-1052

    • DOI

      10.1111/gtc.12092

    • Peer Reviewed
  • [Journal Article] Identification and association study with lung cancer for novel insertion polymorphisms of human endogenous retrovirus.2013

    • Author(s)
      Kahyo T, Tao H, Shinmura K, Sugimura H et al.
    • Journal Title

      Carcinogenesis

      Volume: 34 Pages: 2531-2538

    • DOI

      10.1093/carcin/bgt253

    • Peer Reviewed
  • [Journal Article] Genome-wide association study meta-analysis reveals transethnic replication of mean arterial and pulse pressure loci.2013

    • Author(s)
      Kelly TN, Takeuchi F, Tabara Y, KIta Y et al.
    • Journal Title

      Hypertension

      Volume: 62 Pages: 853-859

    • DOI

      10.1161/HYPERTENSIONAHA.113.01148

    • Peer Reviewed
  • [Journal Article] Association of inflammatory gene polymorphisms and conventional risk factors with arterial stiffness by age.2013

    • Author(s)
      Kheradmand M, Niimura H, Kuwabara, Takezaki T K et al.
    • Journal Title

      Journal of epidemiology / Japan Epidemiological Association

      Volume: 23 Pages: 457-465

    • DOI

      10.2188/jea.JE20130054

    • Peer Reviewed
  • [Journal Article] Visualization of phosphatidylcholine (16:0/16:0) in type II alveolar epithelial cells in the human lung using imaging mass spectrometry.2013

    • Author(s)
      Kurabe N, Hayasaka T, Igarashi H, Sugimura H et al.
    • Journal Title

      Pathology international

      Volume: 63 Pages: 195-200

    • DOI

      10.1111/pin.12050

    • Peer Reviewed
  • [Journal Article] Accumulated phosphatidylcholine (16:0/16:1) in human colorectal cancer; possible involvement of LPCAT4.2013

    • Author(s)
      Kurabe N, Hayasaka T, Ogawa M, Sugimura H et al.
    • Journal Title

      Cancer science

      Volume: 104 Pages: 1295-302

    • DOI

      10.1111/cas.12221

    • Peer Reviewed
  • [Journal Article] SGOL1 variant B induces abnormal mitosis and resistance to taxane in non-small cell lung cancers.2013

    • Author(s)
      Matsuura S, Kahyo T, Shinmura K, Sugimura H et al.
    • Journal Title

      Scientific reports

      Volume: 3 Pages: 3012

    • DOI

      10.1038/srep03012

    • Peer Reviewed
  • [Journal Article] CD74-ROS1 fusion transcripts in resected non-small cell lung carcinoma.2013

    • Author(s)
      Matsuura S, Shinmura K, Kamo T, Sugimura H et al.
    • Journal Title

      Oncology reports

      Volume: 30 Pages: 1675-1680

    • DOI

      10.3892/or.2013.2630

    • Peer Reviewed
  • [Journal Article] The N-ERC index is a novel monitoring and prognostic marker for advanced malignant pleural mesothelioma.2013

    • Author(s)
      Mori T, Tajima K, Hirama M, Hino O et al.
    • Journal Title

      Journal of thoracic disease

      Volume: 5 Pages: 145-148

    • DOI

      10.3978/j.issn.2072-1439.2013.03.03

    • Peer Reviewed
  • [Journal Article] Large-scale survey of frequency of forest walking and related factors in a Japanese population inhabiting a large city, and comparison of an urban area and a rural area.2013

    • Author(s)
      Morita E, Aoyama K, Tamura T, Naito M, Wakai K et al.
    • Journal Title

      Journal of Forest Research

      Volume: 18 Pages: 454-461

    • DOI

      10.1007/s10310-012-0375-9

    • Peer Reviewed
  • [Journal Article] Endoscopic Molecular Imaging: Status and Future Perspective.2013

    • Author(s)
      Muguruma N, Miyamoto H, Okahisa T, Takayama T.
    • Journal Title

      Clinical endoscopy

      Volume: 46 Pages: 603-610

    • DOI

      10.5946/ce.2013.46.6.603

    • Peer Reviewed
  • [Journal Article] Gene-gene combination effect and interactions among ABCA1, APOA1, SR-B1, and CETP polymorphisms for serum high-density lipoprotein-cholesterol in the Japanese population.2013

    • Author(s)
      Nakamura A, Niimura H, Kuwabara K, Takezaki T, Wakai K, Suzuki S, Ohnaka K, Mikami H, Kubo M, Tanaka H et al.
    • Journal Title

      PloS one

      Volume: 8 Pages: e82046

    • DOI

      10.1371/journal.pone.0082046

    • Peer Reviewed
  • [Journal Article] A common missense variant of monocarboxylate transporter 9 (MCT9/SLC16A9) gene is associated with renal overload gout, but not with all gout susceptibility.2013

    • Author(s)
      Nakayama A, Matsuo H, Shimizu T, Wakai K et al.
    • Journal Title

      Human cell

      Volume: 26 Pages: 133-136

    • DOI

      10.1007/s13577-013-0073-8

    • Peer Reviewed
  • [Journal Article] Prostate cancer stem-like cells/cancer-initiating cells have an autocrine system of hepatocyte growth factor.2013

    • Author(s)
      Nishida S, Hirohashi Y, Torigoe T, Masumori N et al.
    • Journal Title

      Cancer science

      Volume: 104 Pages: 431-436

    • DOI

      10.1111/cas.12104

    • Peer Reviewed
  • [Journal Article] Mesothelin expression is a prognostic factor in cholangiocellular carcinoma.2013

    • Author(s)
      Nomura R, Fujii H, Abe M, Hino O et al.
    • Journal Title

      International surgery

      Volume: 98 Pages: 164-169

    • DOI

      10.9738/INTSURG-D-13-00001.1

    • Peer Reviewed
  • [Journal Article] Repression of cell proliferation and androgen receptor activity in prostate cancer cells by 2'-hydroxyflavanone.2013

    • Author(s)
      Ofude M, Mizokami A, Kumaki M, Namiki M et al.
    • Journal Title

      Anticancer research

      Volume: 33 Pages: 4453-4461

    • Peer Reviewed
  • [Journal Article] Endoscopy of Aberrant Crypt Foci: The Expert Approach.2013

    • Author(s)
      Okamoto K, Takaoka T, Muguruma, Takayama T N et al.
    • Journal Title

      Video Journal and Encyclopedia of GI Endoscopy

      Volume: 1 Pages: 357-358

    • DOI

      10.1016/S2212-0971(13)70156-0

    • Peer Reviewed
  • [Journal Article] Tumor necrosis factor-alpha promotes cholestasis-induced liver fibrosis in the mouse through tissue inhibitor of metalloproteinase-1 production in hepatic stellate cells.2013

    • Author(s)
      Osawa Y, Hoshi M, Yasuda I, Moriwaki H et al.
    • Journal Title

      PloS one

      Volume: 8 Pages: e65251

    • DOI

      10.1371/journal.pone.0065251

    • Peer Reviewed
  • [Journal Article] Liver acid sphingomyelinase inhibits growth of metastatic colon cancer.2013

    • Author(s)
      Osawa Y, Suetsugu A, Matsushima-Nishiwaki R, Moriwaki H et al.
    • Journal Title

      The Journal of clinical investigation

      Volume: 123 Pages: 834-843

    • DOI

      10.1172/JCI65188

    • Peer Reviewed
  • [Journal Article] Racially restricted contribution of immunoglobulin Fcgamma and Fcgamma receptor genotypes to humoral immunity to human epidermal growth factor receptor 2 in breast cancer.2013

    • Author(s)
      Pandey JP, Namboodiri AM, Kistner-Griffin E, Tsugane S et al.
    • Journal Title

      Clinical and experimental immunology

      Volume: 171 Pages: 273-277

    • DOI

      10.1111/cei.12018

    • Peer Reviewed
  • [Journal Article] The effect of acyclic retinoid on the metabolomic profiles of hepatocytes and hepatocellular carcinoma cells.2013

    • Author(s)
      Qin XY, Wei F, Tanokura M, Moriwaki H et al.
    • Journal Title

      PloS one

      Volume: 8 Pages: e82860

    • DOI

      10.1371/journal.pone.0082860

    • Peer Reviewed
  • [Journal Article] Gender-Specific Associations of Perceived Stress and Coping Strategies with C-Reactive Protein in Middle-Aged and Older Men and Women.2013

    • Author(s)
      Shimanoe C, Otsuka Y, Hara M, Tanaka K et al.
    • Journal Title

      International journal of behavioral medicine

      Volume: - Pages: -

    • DOI

      10.1007/s12529-013-9341-y

    • Peer Reviewed
  • [Journal Article] D2-40-positive lymphatic vessel invasion is not a poor prognostic factor in stage I lung adenocarcinoma.2013

    • Author(s)
      Shimizu K, Funai K, Sugimura H et al.
    • Journal Title

      Pathology international

      Volume: 63 Pages: 201-205

    • DOI

      10.1111/pin.12048

    • Peer Reviewed
  • [Journal Article] Obesity and hepatocellular carcinoma: targeting obesity-related inflammation for chemoprevention of liver carcinogenesis.2013

    • Author(s)
      Shimizu M, Tanaka T, Moriwaki H.
    • Journal Title

      Seminars in immunopathology

      Volume: 35 Pages: 191-202

    • DOI

      10.1007/s00281-012-0336-6

    • Peer Reviewed
  • [Journal Article] Two distinct modes of ATR activation orchestrated by Rad17 and Nbs1.2013

    • Author(s)
      Shiotani B, Nguyen HD, Hakansson P, Tahara H et al.
    • Journal Title

      Cell reports

      Volume: 3 Pages: 1651-1662

    • DOI

      10.1016/j.celrep.2013.04.018

    • Peer Reviewed
  • [Journal Article] Early-onset diffuse gastric cancer associated with a de novo large genomic deletion of CDH1 gene.2013

    • Author(s)
      Sugimoto S, Yamada H, Takahashi M, Sugimura H et al.
    • Journal Title

      Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association

      Volume: - Pages: -

    • DOI

      10.1007/s10120-013-0278-2

    • Peer Reviewed
  • [Journal Article] Editorial: an obsession with subtyping gastric cancer.2013

    • Author(s)
      Sugimura H.
    • Journal Title

      Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association

      Volume: 16 Pages: 451-453

    • DOI

      10.1007/s10120-013-0243-0

    • Peer Reviewed
  • [Journal Article] Obesity/weight gain and breast cancer risk: findings from the Japan collaborative cohort study for the evaluation of cancer risk.2013

    • Author(s)
      Suzuki S, Kojima M, Tokudome S, Wakai K, Tamakoshi A et al.
    • Journal Title

      Journal of epidemiology / Japan Epidemiological Association

      Volume: 23 Pages: 139-145

    • DOI

      10.2188

    • Peer Reviewed
  • [Journal Article] Ethnic differences in GRHPR mutations in patients with primary hyperoxaluria type 2.2013

    • Author(s)
      Takayama T, Takaoka N, Nagata M, Sugimura H et al.
    • Journal Title

      Clinical genetics

      Volume: - Pages: -

    • DOI

      10.1111/cge.12292

    • Peer Reviewed
  • [Journal Article] Significant association of urokinase plasminogen activator Pro141Leu with serum lipid profiles in a Japanese population.2013

    • Author(s)
      Tamura T, Morita E, Kawai S, Naito M, Wakai K et al.
    • Journal Title

      Gene

      Volume: 524 Pages: 363-367

    • DOI

      10.1016/j.gene.2013.04.046

    • Peer Reviewed
  • [Journal Article] Behavioral and clinical correlates of serum bilirubin concentrations in Japanese men and women.2013

    • Author(s)
      Tanaka M, Budhathoki S, Hirata A, Ohnaka K et al.
    • Journal Title

      BMC endocrine disorders

      Volume: 13 Pages: 39

    • DOI

      10.1186/1472-6823-13-39

    • Peer Reviewed
  • [Journal Article] Suppressive effect of RAS inhibitor manumycin A on aberrant crypt foci formation in the azoxymethane-induced rat colorectal carcinogenesis model.2013

    • Author(s)
      Tsuda M, Okamoto K, Muguruma N, Takayama T et al.
    • Journal Title

      Journal of gastroenterology and hepatology

      Volume: 28 Pages: 1616-1623

    • DOI

      10.1111/jgh.12287

    • Peer Reviewed
  • [Journal Article] Wake-up stroke: incidence, risk factors and outcome of acute stroke during sleep in a Japanese population. Takashima Stroke Registry 1988-2003.2013

    • Author(s)
      Turin TC, Kita Y, Rumana N et al.
    • Journal Title

      European neurology

      Volume: 69 Pages: 354-359

    • DOI

      10.1159/000346124

    • Peer Reviewed
  • [Journal Article] Abundant daily non-sedentary activity is associated with reduced prevalence of metabolic syndrome and insulin resistance.2013

    • Author(s)
      Uemura H, Katsuura-Kamano S, Yamaguchi M, Arisawa K et al.
    • Journal Title

      Journal of endocrinological investigation

      Volume: 36 Pages: 1069-1075

    • DOI

      10.3275/9066

    • Peer Reviewed
  • [Journal Article] Consumption of coffee, not green tea, is inversely associated with arterial stiffness in Japanese men.2013

    • Author(s)
      Uemura H, Katsuura-Kamano S, Yamaguchi M, Arisawa K et al.
    • Journal Title

      European journal of clinical nutrition

      Volume: 67 Pages: 1109-1114

    • DOI

      10.1038/ejcn.2013.132

    • Peer Reviewed
  • [Journal Article] A family history of diabetes is not associated with arterial stiffness in non-diabetic Japanese population.2013

    • Author(s)
      Uemura H, Katsuura-Kamano S, Yamaguchi M, Arisawa K et al.
    • Journal Title

      Open J Epidemiol

      Volume: 3 Pages: 177-183

    • DOI

      10.4236/ojepi.2013.34026

    • Peer Reviewed
  • [Journal Article] Genome-wide association study of genetic factors related to confectionery intake: potential roles of the ADIPOQ gene.2013

    • Author(s)
      Wakai K, Matsuo K, Matsuda F et al.
    • Journal Title

      Obesity

      Volume: 21 Pages: 2413-2419

    • DOI

      10.1002/oby.20316

    • Peer Reviewed
  • [Journal Article] Dietary polyphenols and colorectal cancer risk: the Fukuoka colorectal cancer study.2013

    • Author(s)
      Wang ZJ, Ohnaka K, Morita M et al.
    • Journal Title

      World journal of gastroenterology : WJG

      Volume: 19 Pages: 2683-2690

    • DOI

      10.3748/wjg.v19.i17.2683

    • Peer Reviewed
  • [Journal Article] Management of prostate cancer in Asia: resource-stratified guidelines from the Asian Oncology Summit 20132013

    • Author(s)
      Williams S, Chiong E, Lojanapiwat B, Akaza H et al.
    • Journal Title

      The lancet oncology

      Volume: 14 Pages: e524-34

    • DOI

      10.1016/S1470-2045(13)70451-0

    • Peer Reviewed
  • [Journal Article] Relationship of dietary factors and habits with sleep-wake regularity.2013

    • Author(s)
      Yamaguchi M, Uemura H, Katsuura-Kamano S, Arisawa K et al.
    • Journal Title

      Asia Pacific journal of clinical nutrition

      Volume: 22 Pages: 457-465

    • DOI

      10.6133/apjcn.2013.22.3.01

    • Peer Reviewed
  • [Journal Article] Potential contribution of a novel Tax epitope-specific CD4+ T cells to graft-versus-Tax effects in adult T-cell leukemia patients after allogeneic hematopoietic stem cell transplantation.2013

    • Author(s)
      Tamai Y, Hasegawa A, Takamori A, Sasada A, Tanosaki R, Choi I, Utsunomiya A, Maeda Y, Yamano Y, Eto T, Koh KR, Nakamae H, Suehiro Y, Kato K, Takemoto S, Okamura J, Uike N, and Kannagi M.
    • Journal Title

      J. Immunol

      Volume: 190 Pages: 4382-4392

    • DOI

      10.4049/ JImmunol.1202971

    • Peer Reviewed
  • [Journal Article] Interferon-α (IFN-α) suppresses HTLV-1 gene expression and cell cycling, while IFN-α combined with zidovudin induces p53 signaling and apoptosis in HTLV-1-infected cells.2013

    • Author(s)
      Kinpara S, Kijiyama M, Takamori A, Hasegawa A, Sasada A, Masuda T, Tanaka Y, Utsunomiya A, and Kannagi M.
    • Journal Title

      Retrovirology

      Volume: 10 Pages: 52

    • DOI

      10.1186/ 1742-4690-10-52

    • Peer Reviewed
  • [Journal Article] Stevens-Johnson Syndrome associated with mogamulizumab treatment of Adult T-cell leukemia/lymphoma.2013

    • Author(s)
      Ishida T, Ito A, Sato F, Kusumoto S, Iida S, Inagaki H, Morita A, Akinaga S, Ueda R.
    • Journal Title

      Cancer Sci.

      Volume: 104 Pages: 647-650

    • DOI

      10.1111/cas.12116

    • Peer Reviewed
  • [Journal Article] Impact of GVHD on allogeneic hematopoietic cell transplantation for adult T-cell leukemia-lymphoma focusing on preconditioning regimens: nationwide retrospective study Biology of Blood and Marrow Transplantation.2013

    • Author(s)
      Ishida T, Hishizawa M, Kato K, Tanosaki R, Fukuda T, Takatsuka Y, Eto T, Miyazaki Y, Hidaka M, Uike N, Miyamoto T, Tsudo M, Sakamaki H, Morishima Y, Suzuki R, Utsunomiya A.
    • Journal Title

      Biol Blood Marrow Transplant.

      Volume: 19 Pages: 1731-1739

    • DOI

      10.1016/j.bbmt.2013.09.014

    • Peer Reviewed
  • [Journal Article] Characterization of simian T-cell leukemia virus type 1 in naturally infected Japanese macaques as a model of HTLV-1 infection.2013

    • Author(s)
      Miura M, Yasunaga J-I, Tanabe J, Sugata K, Zhao T, Ma G, Miyazato P, Ohshima K, Kaneko A, Watanabe A, Saito A, Akari H and Matsuoka M.
    • Journal Title

      Retrovirology

      Volume: 10 Pages: 118

    • DOI

      10.1186/1742-4690-10-118.

    • Peer Reviewed
  • [Journal Article] HTLV-1 bZIP factor induces inflammation through labile Foxp3 expression.2013

    • Author(s)
      Yamamoto-Taguchi N, Satou Y, Miyazato P, Ohshima K, Nakagawa M, Katagiri K, Kinashi T, and Matsuoka M.
    • Journal Title

      PLoS Pathogens

      Volume: 9 Pages: e1003630

    • DOI

      10.1371/journal.ppat.1003630.

    • Peer Reviewed
  • [Journal Article] HTLV-1 bZIP factor dysregulates the Wnt pathways to support proliferation and migration of adult T-cell leukemia cells.2013

    • Author(s)
      Ma G, Yasunaga J-I, Fan J, Yanagawa S-I, Matsuoka M.
    • Journal Title

      Oncogene

      Volume: 32 Pages: 4222-4230

    • DOI

      10.1038/onc.2012.450

    • Peer Reviewed
  • [Journal Article] Natural OX40L expressed on human T cell leukemia virus type-I-immortalized T cell lines interferes with infection of activated peripheral blood mononuclear cells by CCR5-utilizing human immunodeficiency virus.2013

    • Author(s)
      Kasahara D, Takara A, Takahashi Y, Kodama A, Tanaka R, Ansari AA, Tanaka Y.
    • Journal Title

      Virol J.

      Volume: 18 Pages: 10:338

    • DOI

      10.1186/1743-422X-10-338.

    • Peer Reviewed
  • [Journal Article] Increased expression of OX40 isassociated with progressive disease in patients with HTLV-1-associatedmyelopathy/tropical spastic paraparesis.2013

    • Author(s)
      Saito M, Tanaka R, Arishima S, Matsuzaki T, Ishihara S, Tokashiki T, Ohya Y, Takashima H, Umehara F, Izumo S, Tanaka Y.
    • Journal Title

      Retrovirology.

      Volume: 10 Pages: 51

    • DOI

      10.1186/1742-4690-10-51

    • Peer Reviewed
  • [Journal Article] HTLV-1 Tax oncoprotein stimulates ROS production and apoptosis in T cells by interacting with USP10.2013

    • Author(s)
      Takahashi M, Higuchi M, Makokha GN, Matsuki H, Yoshita M, Tanaka Y, Fujii M.
    • Journal Title

      Blood.

      Volume: 122(5) Pages: 715-725

    • DOI

      10.1182/blood-2013-03-493718.

    • Peer Reviewed
  • [Journal Article] Genome-wide determinants of proviral targeting, clonal abundance and expression in natural HTLV-1 infection.2013

    • Author(s)
      Melamed A, Laydon DJ, Gillet NA, Tanaka Y, Taylor GP, Bangham CR.
    • Journal Title

      PLoS Pathog.

      Volume: 9(3) Pages: e1003271

    • DOI

      10.1371/journal.ppat.1003271.

    • Peer Reviewed
  • [Journal Article] Adult T-cell leukemia cells are characterized by abnormalities of Helios expression that promotes T-cell growth.2013

    • Author(s)
      Asanuma S, Yamagishi M, Kawanami K, Nakano K, Sato-Otsubo A, Muto S, Sanada M, Yamochi T, Kobayashi S, Utsunomiya A, Iwanaga M, Yamaguchi K, Uchimaru K, Ogawa S, Watanabe T.
    • Journal Title

      Cancer Sci

      Volume: 104(8) Pages: 1097-1106

    • DOI

      10.1111/cas.12181

    • Peer Reviewed
  • [Journal Article] Forefront studies on HTLV-1 oncogenesis.2013

    • Author(s)
      Mahieux R, Watanabe T.
    • Journal Title

      Front Microbiol

      Volume: 4 Pages: 156

    • DOI

      10.3389/fmicb.2013.00156

    • Peer Reviewed
  • [Journal Article] Viral interference with host mRNA surveillance, the nonsense-mediated mRNA decay (NMD) pathway, through a new function of HTLV-1 Rex: implications for retroviral replication.2013

    • Author(s)
      Nakano K, Ando T, Yamagishi M, Yokoyama K, Ishida T, Ohsugi T, Tanaka Y, Brighty D-W, Watanabe T.
    • Journal Title

      Microbes Infect

      Volume: 15(6-7) Pages: 491-505

    • DOI

      10.1016/j.micinf.2013.03.006

    • Peer Reviewed
  • [Journal Article] RASEF is a novel diagnostic biomarker and a therapeutic target for lung cancer.2013

    • Author(s)
      Oshita H, Nishino R, Takano A, Fujitomo T, Aragaki M, Kato T, Akiyama H, Tsuchiya E, Kohno N, Nakamura Y, Daigo Y.
    • Journal Title

      Mol Cancer Res

      Volume: 11 Pages: 937-951

    • DOI

      10.1158/1541-7786.MCR-12-0685-T

    • Peer Reviewed
  • [Journal Article] A Systematic Approach to the Development of Novel Therapeutics for Lung Cancer using Genomic Analyses.2013

    • Author(s)
      Daigo Y, Takano A, Teramoto K, Chung S, Nakamura Y.
    • Journal Title

      Clin Pharmacol Ther

      Volume: 94 Pages: 218-223

    • DOI

      10.1038/clpt.2013.90.

    • Peer Reviewed
  • [Journal Article] Deregulation of the histone demethylase JMJD2A is involved in human carcinogenesis through regulation of the G1/S transition.2013

    • Author(s)
      Kogurea M, Takawa M, Cho HS, Toyokawa G, Hayashi K, Tsunoda T, Kobayashi T, Daigo Y, Sugiyama M, Atomi Y, Nakamura Y, Hamamoto R.
    • Journal Title

      Cancer Lett

      Volume: 336 Pages: 76-84

    • DOI

      10.1016/j.canlet.2013.04.009.

    • Peer Reviewed
  • [Journal Article] NKX2-1/TTF-1: an enigmatic oncogene that functions as a double-edged sword for cancer cell survival and progression.2013

    • Author(s)
      Yamaguchi T, Hosono Y, Yanagisawa K, Takahashi T.
    • Journal Title

      Cancer Cell

      Volume: 23 Pages: 718-723

    • DOI

      10.1016/j.ccr.2013.04.002

    • Peer Reviewed
  • [Journal Article] Met is the most frequently amplified gene in endometriosis-associated ovarian clear cell adenocarcinoma and correlates with worsened prognosis.2013

    • Author(s)
      Yamashita Y, Akatsuka S, Shinjo K, Yatabe Y, Kobayashi H, Seko H, Kajiyama H, Kikkawa F, Takahashi T, Toyokuni S.
    • Journal Title

      PLoS ONE

      Volume: 8 Pages: e57724

    • DOI

      10.1371/journal.pone.0057724

    • Peer Reviewed
  • [Journal Article] Secretome-based identification of TFPI2, a novel serum biomarker for detection of ovarian clear cell adenocarcinoma.2013

    • Author(s)
      Arakawa N, Miyagi E, Nomura A, Morita E, Ino Y, Ohtake N, Miyagi Y, Hirahara F, Hirano H.
    • Journal Title

      J Proteome Res

      Volume: 12(10) Pages: 4340-4350

    • DOI

      10.1021/pr400282j.

    • Peer Reviewed
  • [Journal Article] Rapid detection of SNP (c.309T>G) in the MDM2 gene by the Duplex SmartAmp method.2013

    • Author(s)
      Enokida Y, Shimizu K, Atsumi J, Lezhava A, Tanaka Y, Kimura Y, Soma T, Hanami T, Kawai Y, Usui K, Okano Y, Kakegawa S, Ogawa H, Miyamae Y, Miyagi Y, Nakayama H, Ishikawa T, Hayashizaki Y, Takeyoshi I.
    • Journal Title

      PLoS ONE

      Volume: 8(4) Pages: e60151

    • DOI

      10.1371/journal.pone.0060151

    • Peer Reviewed
  • [Journal Article] Total synthesis of bicyclic depsipeptides spiruchostatins C and D and investigation of their histone deacetylase inhibitory and antiproliferative activities.2013

    • Author(s)
      Narita K, Fukui Y, Sano Y, Yamori T, Ito A, Yoshida M, Katoh T.
    • Journal Title

      Eur. J. Med. Chem.

      Volume: 60 Pages: 295-304

    • DOI

      10.1016/j.ejmech.2012.12.023

    • Peer Reviewed
  • [Journal Article] HCV NS3 protease enhances liver fibrosis via binding to and activating TGF-β type I receptor.2013

    • Author(s)
      Sakata K, Eda S, Lee E, Hara M, Imoto M, Kojima S.
    • Journal Title

      Scientific Reports.

      Volume: 3 Pages: 3243

    • DOI

      10.1038/srep03243

    • Peer Reviewed
  • [Journal Article] Inhibition of ATP citrate lyase induces an anticancer effect via reactive oxygen species: AMPK as a predictive biomarker for therapeutic impact.2013

    • Author(s)
      Migita T, Okabe S, Ikeda K, Igarashi S, Sugawara S, Tomida A, Taguchi R, Soga T, Seimiya H.
    • Journal Title

      Am J Pathol.

      Volume: 182(5) Pages: 1800-1810

    • DOI

      10.1016/j.ajpath.2013.01.048

    • Peer Reviewed
  • [Journal Article] Intervenolin, a new antitumor compound with anti-Helicobacter pylori activity, from Nocardia sp. ML96-86F2.2013

    • Author(s)
      Kawada M, Inoue H, Ohba S, Hatano M, Amemiya M, Hayashi C, Usami I, Abe H, Watanabe T, Kinoshita N, Igarashi M, Masuda T, Ikeda D, Nomoto A.
    • Journal Title

      J Antibiot (Tokyo)

      Volume: 66(9) Pages: 543-548

    • DOI

      10.1038/ja.2013.42.

    • Peer Reviewed
  • [Journal Article] Spectomycin B1 as a novel SUMOylation inhibitor that directly binds to SUMO E2.2013

    • Author(s)
      Hirohama M, Kumar A, Fukuda I, Matsuoka S, Igarashi Y, Saitoh H, Takagi M, Shin-Ya K, Honda K, Kondoh Y, Saito T, Nakao Y, Osada H, Zhang KY, Yoshida M, Ito A.
    • Journal Title

      ACS Chem Biol.

      Volume: 8(12) Pages: 2635-2642

    • DOI

      10.1021/cb400630z

    • Peer Reviewed
  • [Journal Article] Identification of small molecule inhibitors of p27Kip1 ubiquitination by high-throughput screening.2013

    • Author(s)
      Ooi LC, Watanabe N, Futamura Y, Sulaiman SF, Darah I, Osada H.
    • Journal Title

      Cancer Sci.

      Volume: 104(11) Pages: 1461-1467

    • DOI

      10.1111/cas.12246

    • Peer Reviewed
  • [Journal Article] Ridaifen-SB8, a novel tamoxifen derivative, induces apoptosis via reactive oxygen species-dependent signaling pathway.2013

    • Author(s)
      Guo WZ, Shiina I, Wang Y, Umeda E, Watanabe C, Uetake S, Ohashi Y, Yamori T, Dan S.
    • Journal Title

      Biochem Pharmacol.

      Volume: 86(9) Pages: 1272-1284

    • DOI

      10.1016/j.bcp.2013.08.020.

    • Peer Reviewed
  • [Journal Article] Lysine-Specific Demethylase 1-Selective Inactivators: Protein-Targeted Drug Delivery Mechanism.2013

    • Author(s)
      Ogasawara D, Itoh Y, Tsumoto H, Kakizawa T, Mino K, Fukuhara K, Nakagawa H, Hasegawa M, Sasaki R, Mizukami T, Miyata N, Suzuki T.
    • Journal Title

      Angew. Chem. Int. Ed.

      Volume: 52 Pages: 8620- 8624

    • DOI

      10.1002/anie.201303999

    • Peer Reviewed
  • [Journal Article] Identification of the KDM2/7 Histone Lysine Demethylase Subfamily Inhibitor and its Antiproliferative Activity.2013

    • Author(s)
      Suzuki T, Ozasa H, Itoh Y, Zhan P, Sawada H, Mino K, Walport L, Ohkubo R, Kawamura A, Yonezawa M, Tsukada Y, Tumber A, Nakagawa H, Hasegawa M, Sasaki R, Mizukami T, Schofield CJ, Miyata N.
    • Journal Title

      J. Med. Chem.

      Volume: 56 Pages: 7222-7231

    • DOI

      10.1021/jm400624b

    • Peer Reviewed
  • [Journal Article] RASSF1A methylation indicates a poor prognosis in hepatoblastoma patients.2013

    • Author(s)
      Honda S, Miyagi H, Suzuki H, Minato M, Haruta M, Kaneko Y, Hatanaka KC, Hiyama E, Kamijo T, Okada T, Taketomi A.
    • Journal Title

      Pediatr Surg Int

      Volume: 29 Pages: 1147-1152

    • Peer Reviewed
  • [Presentation] Cancer as a ferrotoxic disease. Symposium 1: Redox-active ion in disease pathology and treatment.2014

    • Author(s)
      Toyokuni S.
    • Organizer
      17th Biennial Meeting of the Society for Free Radical Research International
    • Place of Presentation
      Kyoto International Conference Center, Kyoto, Japan
    • Year and Date
      20140323-20140326
    • Invited
  • [Presentation] A combination of the anti-fibroblast growth factor receptor 1 monoclonal antibody and interferon-a/b supresses human hepatic cancer cells in vitro and in vivo2014

    • Author(s)
      Kato Y, Hiromi H, Tujisaki M, Matsune T, Sasaki S, Hinoda Y, Shinomura Y, Imai K
    • Organizer
      41 Congress of the International Society of Oncology and Biomarkers
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      20140315-20140318
  • [Presentation] Critical factors in multi-walled carbon nanotubes in mesothelial carcinogenesis.2014

    • Author(s)
      Toyokuni S.
    • Organizer
      The 46th Fullerenes-Nanotubes-Graphene General Symposium.
    • Place of Presentation
      The University of Tokyo, Ito International Research Center 、東京都文京区
    • Year and Date
      20140303-20140305
    • Invited
  • [Presentation] 骨微小環境における腫瘍細胞増殖メカニズム:動物モデルを用いた解析2014

    • Author(s)
      二口 充
    • Organizer
      平成25年度「個体レベルでのがん支援活動」ワークショップ 2014
    • Place of Presentation
      琵琶湖ホテル、滋賀県大津市
    • Year and Date
      20140217-20140218
  • [Presentation] Impact of interferon response in HTLV-1 infection: a molecular mechanism of AZT/IFN-a therapy for ATL.2014

    • Author(s)
      Kannagi M, Kinpara S, Hasegawa A.
    • Organizer
      第4回発がんスパイラル国際シンポジウム
    • Place of Presentation
      Sapporo
    • Year and Date
      20140210-20140211
    • Invited
  • [Presentation] Isoflavones in Japanese and Caucasian men with prostate cancer in Hawaii2014

    • Author(s)
      Fukagai T, Akaza H, Ogawa Y, Carlile R, Namiki T, Lederer JL, Maskarinec G, Tsuji H, Moriyama K, Fujimoto K, Hirao Y, Namiki M
    • Organizer
      2014 Genitourinary Cancer Symposium
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      20140129-20140203
  • [Presentation] Invited lecture 2: Role of iron in carcinogenesis.2014

    • Author(s)
      Toyokuni S.
    • Organizer
      SFRR India
    • Place of Presentation
      Lonavala, India
    • Year and Date
      20140127-20140130
    • Invited
  • [Presentation] Growh of malignant tumor in the bone microenvironment.2013

    • Author(s)
      M. Futakuchi
    • Organizer
      The 18th Korea- Japan Cancer Research Workshop 2013
    • Place of Presentation
      Gifu
    • Year and Date
      20131129-20131201
    • Invited
  • [Presentation] HTLV-1 bZIP factor determines cell tropism2013

    • Author(s)
      Matsuoka M
    • Organizer
      The 3rd French Japanese Cancer Research Workshop
    • Place of Presentation
      Hotel Mercure Toulouse Compans Caffarelli, Toulouse, France.
    • Year and Date
      20131120-20131123
  • [Presentation] シンポジウム1 細胞ストレス応答の分子機構と疾患病態:酸化ストレスによる発がん機構の解明2013

    • Author(s)
      豊國伸哉
    • Organizer
      第8回臨床ストレス応答学会
    • Place of Presentation
      信州大学、松本市
    • Year and Date
      20131115-20131116
  • [Presentation] 生活習慣病の遺伝子環境交互作用の解明を目指して:日本多施設共同コーホート研究-佐賀地区-(特別講演)2013

    • Author(s)
      田中恵太郎
    • Organizer
      第78回日本民族衛生学会総会
    • Place of Presentation
      佐賀市
    • Year and Date
      20131115-20131116
  • [Presentation] ヒトT細胞白血病ウイルス1型による発がん:TaxとHBZの拮抗と協調2013

    • Author(s)
      松岡雅雄、安永純一朗
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸国際会議場(兵庫県)
    • Year and Date
      20131110-20131112
  • [Presentation] ウイルス複製を有利にするHTLV-1 Rexの新たな機能と宿主細胞への影響 シンポジウム1発癌ウイルス2013

    • Author(s)
      渡邉俊樹
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸
    • Year and Date
      20131110-20131112
    • Invited
  • [Presentation] ゼブラフィッシュ胚を用いたWnt/β-catenin経路ケミカルサプレッサーの探索2013

    • Author(s)
      西谷直之, 河野富一, 上原至雅.
    • Organizer
      日本薬学会生薬天然物部会主催・第5回食品薬学シンポジウム
    • Place of Presentation
      京都
    • Year and Date
      20131101-20131102
  • [Presentation] その研究に、阻害剤キットあります―化学療法基盤支援活動2013

    • Author(s)
      川田学
    • Organizer
      日本薬学会生薬天然物部会主催・第5回食品薬学シンポジウム
    • Place of Presentation
      京都
    • Year and Date
      20131101-20131102
  • [Presentation] Oocyte cryopreservation and IVF2013

    • Author(s)
      Takeo, T., Ishizuka,Y., Fukumoto, K., Kondo, T., Haruguchi, Y., Takeshita, Y., Nakamuta, Y., Umeno, T., Tsuchiyama, S., Nakagata, N.
    • Organizer
      1st Oceania Transgenic Technology/Cryopreservation Symposium
    • Place of Presentation
      Brisbane, Australia
    • Year and Date
      20131031-20131101
    • Invited
  • [Presentation] Critical factors in multi-walled carbon nanotubes for mesothelial carcinogenesis.2013

    • Author(s)
      Toyokuni S, Nagai H, Okazaki Y, Chew SH, Akatsuka S, Jiang L and Ichihara G.
    • Organizer
      6th International Symposium on Nanotechnology, Occupational and Environmental Health.
    • Place of Presentation
      Nagoya Congress Center, Nagoya, Japan
    • Year and Date
      20131028-20131031
    • Invited
  • [Presentation] In vitro fertilization using frozen-thawed genetically engineered mouse sperm derived from cold-transported epididymides2013

    • Author(s)
      Nakagata, N., Fukumoto, K., Haruguchi, Y., Kondo, T., Takeshita, Y., Nakamuta, Y., Matsunaga, H., Umeno, T., Nishimura, M., Iwamoto, M., Takahashi, F., Kohagura, E., Tsuchiyama, S., Takeo, T.
    • Organizer
      64th AALAS National Meeting
    • Place of Presentation
      Baltimore, MD USA
    • Year and Date
      20131027-20131031
  • [Presentation] Genetic techniques: Classical and advanced methods. Seminar: Quality animals are essential for quality research.2013

    • Author(s)
      Katoh, H.
    • Organizer
      64th AALAS National Meeting.
    • Place of Presentation
      Baltimore, MD, USA.
    • Year and Date
      20131027-20131031
  • [Presentation] Plenary talk 2. Role of iron in carcinogenesis.2013

    • Author(s)
      Toyokuni S.
    • Organizer
      6th Biennial Meeting of Society for Free Radical Research Asia
    • Place of Presentation
      Chang Gung University, Tao-Yuan, Taiwan
    • Year and Date
      20131016-20131019
    • Invited
  • [Presentation] パネルディスカッション1「C型肝炎を背景とした肝細胞癌―予防から再発治療まで―」非環式レチノイドと分岐鎖アミノ酸を用いた肝発癌抑制―肥満関連肝発癌抑制と両剤の併用投与による相乗的肝癌細胞増殖抑制―.2013

    • Author(s)
      清水雅仁、白上洋平、森脇久隆.
    • Organizer
      JDDW2013
    • Place of Presentation
      東京
    • Year and Date
      20131009-20131012
  • [Presentation] シンポジウム:がん研究とモデル動物(モデレーター、座長) モデル動物から明らかになった過剰鉄と発がんの親和性2013

    • Author(s)
      豊國伸哉
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜、横浜市
    • Year and Date
      20131003-20131005
  • [Presentation] Growth of malignant tumor in the bone microenvironment; mechanism of bone metastasis and its therapeutic targets.2013

    • Author(s)
      M. Futakuchi, K. Fukamachi, M. Suzui.
    • Organizer
      72nd Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      パシフィコ横浜、横浜市
    • Year and Date
      20131003-20131005
  • [Presentation] ”移民研究から推定されるがん予防効果”、シンポジウム: 19:がん疫学研究:国民全体および個別化の確かながん予防実現に向けて2013

    • Author(s)
      岩崎 基、津金昌一郎
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      20131003-20131005
  • [Presentation] 「ATLに対するHTLV-1 Tax特異的T細胞応答賦活化ペプチドパルス樹状細胞を用いた免疫療法」第一相臨床試験,2013

    • Author(s)
      Suehiro Y, Hasegawa A, Iino T, Sasada A, Watanabe N, Tanosaki R, Utsunomiya A, Matsuoka M, Teshima T, Akashi K, Okamura J, Kannagi M and Uike N.
    • Organizer
      第72回日本癌学会シンポジウム
    • Place of Presentation
      横浜
    • Year and Date
      20131003-20131005
  • [Presentation] リンパ腫におけるエピジェネティック依存的なmiRNAの発現異常とシグナル伝達系の活性化2013

    • Author(s)
      山岸誠、片野晴隆、中川翔太、中野和民、太田泰徳、比島恒和、岡田誠治、渡邉俊樹
    • Organizer
      腫瘍別シンポジウム、第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜、横浜
    • Year and Date
      20131003-20131005
  • [Presentation] Multifaceted dissection of genetic regulatory circuitry involved in the pathogenesis of lung cancers.2013

    • Author(s)
      Takahashi T.
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      20131003-20131005
  • [Presentation] Geranylgeranyltransferase as a potential molecular target for Wnt/beta-catenin pathway inhibitors2013

    • Author(s)
      Nishiya N, Oku Y, Uehara Y.
    • Organizer
      日本癌学会 第72回総会
    • Place of Presentation
      横浜
    • Year and Date
      20131003-20131005
  • [Presentation] 抗がん剤探索アプローチの変遷と最近の話題2013

    • Author(s)
      清宮啓之
    • Organizer
      日本癌学会学術総会(モーニングレクチャー)
    • Place of Presentation
      横浜
    • Year and Date
      20131003-20131005
  • [Presentation] Chemical biology for anticancer agents(抗がん剤のケミカルバイオロジー)2013

    • Author(s)
      長田裕之
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      20131003-20131005
  • [Presentation] <Poster Session: Genitourinary Malignancies - Prostate Cancer> A multicenter Phase 1-2 study of enzalutamide in Japanese patients with castration-resistant prostate cancer (CRPC), who had received combined androgen blockade (CAB)2013

    • Author(s)
      Akaza H, Uemura H, Tsukamoto T, Ozono S, Ogawa O, Sakai H, Oya M, Namiki M, Ohashi Y, Naito S
    • Organizer
      The European Cancer Congress 2013
    • Place of Presentation
      Amsterdam, Netherlands
    • Year and Date
      20130927-20131001
  • [Presentation] 骨微小環境における前立腺癌および乳癌の増殖メカニズムに着目した骨転移治療薬の開発と展開2013

    • Author(s)
      二口 充
    • Organizer
      第24回新薬創製懇話会
    • Place of Presentation
      沼津
    • Year and Date
      20130925-20130926
    • Invited
  • [Presentation] “Chemistry and biology of Xanthohumol, an inhibitor of Valosin-Containing Protein.”2013

    • Author(s)
      井本正哉
    • Organizer
      EMBO Workshop【AAA+ proteins: from mechanism and disease to targets】
    • Place of Presentation
      Germany・Neuss
    • Year and Date
      20130916-20130920
  • [Presentation] How human T-cell leukemia virus type 1 induces diseases2013

    • Author(s)
      Matsuoka M
    • Organizer
      FRONTIERS OF RETROVIROLOGY
    • Place of Presentation
      Churchill College, Cambridge University, UK.
    • Year and Date
      20130916-20130918
  • [Presentation] Hematological neoplasms and viral Infections2013

    • Author(s)
      Watanabe T
    • Organizer
      XXVI Symposium IACRLRD
    • Place of Presentation
      Lingotto Conference Center, Torino, Italy
    • Year and Date
      20130911-20130914
  • [Presentation] Molecular Pathogenesis by HTLV-1 bZIP Factor2013

    • Author(s)
      Matsuoka M
    • Organizer
      The 15th Annual International Meeting of the Institute of Human Virology
    • Place of Presentation
      Moscow, Russia
    • Year and Date
      20130908-20130912
  • [Presentation] ラットのアスベスト誘発中皮腫発がんモデルにおいてDeferasirox投与は 間質上皮移行を促進する2013

    • Author(s)
      豊國伸哉、永井裕崇、岡崎泰昌、周 珊瑚、三澤伸明、安井裕之
    • Organizer
      第37回日本鉄バイオサイエンス学会学術集会
    • Place of Presentation
      JA共済ビル・カンファレンスホール、東京
    • Year and Date
      20130907-20130908
  • [Presentation] Applications of Cryopreserved Mouse Oocytes for In vitro Fertilization Using Fresh, Cold-stored and Frozen Sperm2013

    • Author(s)
      Ishizuka,Y., Yoshimoto,H., Sakoh, K., Nakao, S., Horikoshi, Y., Hirose, Y., Takeuji, S., Sakai, Y., Maeda, Y., Hachiya, M., Mukunoki, A., Takeo, T., Nakagata,N.
    • Organizer
      ANZLAA conference
    • Place of Presentation
      Perth, Australia
    • Year and Date
      20130904-20130906
  • [Presentation] シンポジウム「レチノイド研究温故知新―レチノイドの新たな作用点を求めて―」非環式レチノイドによる肝発癌化学予防 ―Chemoprevention of hepatocellular carcinoma by acyclic retinoid―2013

    • Author(s)
      清水雅仁、森脇久隆
    • Organizer
      日本レチノイド研究会第24回学術集会
    • Place of Presentation
      東京
    • Year and Date
      20130830-20130831
  • [Presentation] ウィルス複製を有利にするHTLV-1 Rexの新たな機能の可能性と宿主細胞への影響2013

    • Author(s)
      中野和民、安東友美、山岸誠、横山弘一、唐澤伸明、橋爪大明、高橋隆太郎、高橋碧、石田尚臣、大杉剛生、田中勇悦、David W. Brighty、渡邉俊樹
    • Organizer
      第2回ATLシンポジウム、第6回HTLV-1研究会・シンポジウム
    • Place of Presentation
      東京大学医科学研究所
    • Year and Date
      20130823-20130825
  • [Presentation] ヒトT細胞白血病ウイルス1型の病原性発現機構2013

    • Author(s)
      松岡雅雄
    • Organizer
      第37回阿蘇シンポジウム
    • Place of Presentation
      阿蘇リゾートグランヴィリオホテル(熊本)
    • Year and Date
      20130802-20130803
  • [Presentation] Establishment of a live young mouse production system using unfertilized oocytes cryopreserved via a simple vitrification method2013

    • Author(s)
      Nakagata, N., Takeo, T., Fukumoto, K., Kondo, T., Takeshita, Y., Nakamuta, Y., Tsuchiyama, S., Kohagura, E., Iwamoto, M., Takahashi, F., Ishizuka,Y.
    • Organizer
      CRYO2013
    • Place of Presentation
      North Bethesda Marriott and Conference Center, Washington, DC. USA
    • Year and Date
      20130728-20130731
  • [Presentation] International cold-transport of cauda epididymides taken from C57BL/6 mice2013

    • Author(s)
      Nakagata, N., Takeo, T., Fukumoto, K., Kondo, T., Haruguchi, Y., Takeshita, Y., Nakamuta, Y., Matsunaga, H., Umeno, T., Nishimura, M., Tsuchiyama, S., Iwamoto, M., Takahashi, F., Kohagura, E., Guan, M., Fray, D, M., Kinchen, K., Lee, M., Lloyd, K.
    • Organizer
      SSR2013
    • Place of Presentation
      Montreal, Quebec, Canada
    • Year and Date
      20130722-20130726
  • [Presentation] シンポジウム1:環境物質による発がんリスクとその予防 「アスベスト発がん機構の解明から早期発見・予防への展開」2013

    • Author(s)
      豊國 伸哉
    • Organizer
      第20回日本がん予防学会
    • Place of Presentation
      日本薬学会長井記念館、東京都
    • Year and Date
      20130705-20130706
  • [Presentation] シンポジウム:老化と酸化ストレス、そして、再生へ「酸化ストレスと老化の新たな展開」 酸化ストレスと発がんから老化を考える2013

    • Author(s)
      豊國 伸哉
    • Organizer
      第28回老化促進モデルマウス(SAM)研究協議会
    • Place of Presentation
      愛知学院大学、名古屋市
    • Year and Date
      20130705-20130706
    • Invited
  • [Presentation] ワークショップ「炎症および傷害物質に関連した発がんと予防」肝および内臓脂肪の炎症制御を介した分岐鎖アミノ酸による肥満・糖尿病関連肝腫瘍形成の抑制2013

    • Author(s)
      清水雅仁、寺倉大志、河内隆宏、白上洋平、田中卓二、森脇久隆
    • Organizer
      第20回日本がん予防学会
    • Place of Presentation
      東京
    • Year and Date
      20130705-20130706
  • [Presentation] ワークショップ「炎症および傷害物質に関連した発がんと予防」非アルコール性脂肪肝炎関連肝発癌新規モデルとペントキシフィリンによる発癌抑制効果2013

    • Author(s)
      白上洋平、清水雅仁、森脇久隆、清島満
    • Organizer
      第20回日本がん予防学会
    • Place of Presentation
      東京
    • Year and Date
      20130705-20130706
  • [Presentation] Allogeneic BM transplantation in ATL: Whom to transplant and which modality to use? Can we go beyond BM transplantation?2013

    • Author(s)
      Kannagi M.
    • Organizer
      16th International Conference on Human Retrovirology HTLV and Related Viruses,  Clinical trial workshop.
    • Place of Presentation
      Montreal, Canada
    • Year and Date
      20130626-20130630
    • Invited
  • [Presentation] IFN-α suppresses HTLV-1 expression via PKR in infected cells and renders them susceptible to AZT through p53 activation in AZT/IFN-α treatment.2013

    • Author(s)
      Kinpara S, Kijiyama M, Takamori A, Hasegawa A, Sasada A, Masuda T, Tanaka Y, Utsunomiya A, Kannagi M.
    • Organizer
      16th International Conference on Human Retrovirology HTLV and Related Viruses
    • Place of Presentation
      Montreal, Canada
    • Year and Date
      20130626-20130630
  • [Presentation] Uike N. The phase-I study of a therapeutic vaccine to ATL patients with autologous dendritic cells pulsed with peptides corresponding to Tax-specific CTL epitopes.2013

    • Author(s)
      Suehiro Y, Hasegawa A, Iino T, Sasada A, Watanabe N, Choi I, Fukuda T, Takaishi S, Tanosaki R, Utsunomiya A, Miura O, Matsuoka M, Teshima T, Akashi K, Okamura J, Kannagi M,
    • Organizer
      16th International Conference on Human Retrovirology HTLV and Related Viruses.
    • Place of Presentation
      Montreal, Canada
    • Year and Date
      20130626-20130630
  • [Presentation] Augmentation of donor-derived Tax-specific CTL responses by a novel Tax epitope-specific CD4+ helper T-cells in ATL patients after allogeneic hematopoietic stem cell transplanation.2013

    • Author(s)
      Hasegawa A, Tamai Y, Takamori A, Sasada A, Tanosaki R, Choi I, Utsunomiya A, Maeda Y, Yamano Y, Etoh T, Koh KR, Nakamae H, Suehiro Y, Kato K, Takemoto S, Okamura J, Uike N, Kannagi M.
    • Organizer
      16th International Conference on Human Retrovirology HTLV and Related Viruses.
    • Place of Presentation
      Montreal, Canada
    • Year and Date
      20130626-20130630
  • [Presentation] State of the Art Lecture and Session Summary2013

    • Author(s)
      Matsuoka M
    • Organizer
      16th International Conference on Human Retrovirology: HTLV and Related Viruses 2013
    • Place of Presentation
      Montreal, Canada
    • Year and Date
      20130626-20130630
  • [Presentation] Molecular hallmarks of adult T cell leukemia: miRNA, pigenetics, and emerging signaling abnormalities2013

    • Author(s)
      Yamagishi M, Fujikawa D, Kurokawa N, Soejima A, Takahashi R, Sakai N, Nakagawa S, Nakano K, Kobayashi S, Utsunomiya A, Yamaguchi K, Uchimaru K, Ogawa S, Watanabe T
    • Organizer
      16th International Conference on Human Retrovirology HTLV and Related Viruses
    • Place of Presentation
      Montreal, Canada
    • Year and Date
      20130626-20130629
  • [Presentation] 多層カーボンナノチューブの発がん性を決定する物性因子の発見 シンポジウムI:「アイデア」2013

    • Author(s)
      豊國 伸哉
    • Organizer
      第36回日本がん疫学・分子疫学研究会
    • Place of Presentation
      岐阜大学サテライトキャンパス、岐阜市
    • Year and Date
      20130620-20130621
    • Invited
  • [Presentation] 日本多施設共同コーホート研究 (J-MICC Study)―そのミッションと現状―2013

    • Author(s)
      若井建志, 田中英夫
    • Organizer
      第36回日本がん疫学・分子疫学研究会
    • Place of Presentation
      岐阜
    • Year and Date
      20130620-20130621
  • [Presentation] The Efficacy and Safety of Mogamulizumab (KW-0761) in Multicenter Phase II Study for Patients with Relapsed Peripheral or Cutaneous T-Cell Lymphoma (abs 041)2013

    • Author(s)
      Ueda R, Ogura M, Ishida T, Hatake K, Taniwaki M, Ando K, Tobinai K, Fujimoto K, Yamamoto K, Miyamoto T, Uike N, Tanimoto M, Tsukasaki K, Ishizawa K, Suzumiya J, Inagaki H, Tamura K, Akinaga S, Tomonaga M.
    • Organizer
      12th International Conference on Malignant Lymphoma.
    • Place of Presentation
      Lugano, Switzerland.
    • Year and Date
      20130619-20130622
  • [Presentation] Combination of Mogamulizumab (KW-0761) with VCAP-AMP-VECP (mLSG15) is Well Tolerated and Effective as an Initial Therapy for Aggressive Adult T-Cell Leukaemia-Lymphoma (ATL) (abs 154)2013

    • Author(s)
      Takemoto T, Ishida T, Jo T, Uozumi K, Suzushima H, Yamamoto K, Uike N, Saburi Y, Nosaka K, Utsunomiya A, Tobinai K, Fujiwara H, Ishitsuka K, Yoshida S, Taira N, Moriuchi Y, Imada K, Miyamoto T, Tsukasaki K, Tomonaga M, Ueda R.
    • Organizer
      12th International Conference on Malignant Lymphoma.
    • Place of Presentation
      Lugano, Switzerland.
    • Year and Date
      20130619-20130622
  • [Presentation] ナノ材料(CNT)の物性と発がん性 シンポジウム4:ナノマテリアルの評価開発手法における今後の課題2013

    • Author(s)
      豊國 伸哉
    • Organizer
      第40回日本毒性学会学術年会
    • Place of Presentation
      幕張メッセ 国際会議場、千葉市
    • Year and Date
      20130617-20130619
    • Invited
  • [Presentation] EPIGENETIC DEREGULATION OF MIRNA IN MALIGNANT LYMPHOMAS2013

    • Author(s)
      Yamagishi M, Watanabe T
    • Organizer
      18th Congress of EHA
    • Place of Presentation
      Stockholm, Sweden
    • Year and Date
      20130612-20130616
  • [Presentation] Genetic monitoring for inbreds and closed colony strains.2013

    • Author(s)
      Katoh, H.
    • Organizer
      Workshop: Aspects of genetic monitoring in redents. 12th FELASA/SECAL Congress.
    • Place of Presentation
      Barcelona, Spain.
    • Year and Date
      20130610-20130613
  • [Presentation] 酸化ストレスによるゲノム変化と発がん シンポジウム2:細胞ストレス応答の破綻と病態2013

    • Author(s)
      豊國伸哉、蒋 麗、岡崎泰昌、山下依子、赤塚慎也
    • Organizer
      第102回日本病理学会総会
    • Place of Presentation
      ロイトン札幌・さっぽろ芸文館、札幌
    • Year and Date
      20130606-20130608
  • [Presentation] ワークショップ「胆汁酸研究の最新のシンポ」胆汁酸による肝細胞障害および肝線維化におけるTNF-αの役割2013

    • Author(s)
      清水雅仁、寺倉大志、森脇久隆
    • Organizer
      第49回日本肝臓学会総会
    • Place of Presentation
      東京
    • Year and Date
      20130606-20130607
  • [Presentation] Randomized phase II study of mogamulizumab (KW-0761) plus VCAP-AMP-VECP (mLSG15) versus mLSG15 alone for newly diagnosed aggressive adult T-cell leukemia-lymphoma (ATL).2013

    • Author(s)
      Jo T, Ishida T, Takemoto S, Suzushima H, Uozumi K, Yamamoto, K Uike N, Saburi Y, Nosaka K, Utsunomiya A, Tobinai K, Fujiwara H, Ishitsuka K, Yoshida S, Taira N, Moriuchi Y, Imada K, Miyamoto T, Tomonaga M, Ueda R.
    • Organizer
      2013 ASCO Annual Meeting
    • Place of Presentation
      Chicago, USA
    • Year and Date
      20130531-20130604
  • [Presentation] How Human T-cell Leukemia Virus Type 1 induces leukemia2013

    • Author(s)
      Matsuoka M
    • Organizer
      The 4th JSH International Symposium 2013
    • Place of Presentation
      YAMATOYA-HONTEN, Ehime.
    • Year and Date
      20130524-20130525
  • [Presentation] 我が国におけるHTLV-1/ATL研究の現状、大河内メモリアルシンポジウム1:HTLV-1の現状2013

    • Author(s)
      渡邉俊樹
    • Organizer
      第61回日本輸血・細胞治療学会総会
    • Place of Presentation
      パシフィコ横浜、横浜
    • Year and Date
      20130516-20130518
    • Invited
  • [Presentation] Trans-Pacific variation in outcomes for men treated with primary androgen deprivation therapy for localized prostate cancer2013

    • Author(s)
      Cooperberg M, Hinotsu S, Namiki M, Carroll P, Akaza H
    • Organizer
      2013 AUA Annual Meeting
    • Place of Presentation
      San Diego, USA
    • Year and Date
      20130504-20130508
  • [Presentation] TTF-1/NKX2-1: an enigmatic oncogene that functions as a double-edged sword in lung adenocarcinoma.2013

    • Author(s)
      Takahashi T.
    • Organizer
      SNUCRI & SNUCH Cancer Symposium.
    • Place of Presentation
      Jeju, Korea.
    • Year and Date
      20130502-20130504
  • [Presentation] 「再生医療における非臨床試験とは:ヒトiPS細胞を用いたヒト化マウス」

    • Author(s)
      山村研一
    • Organizer
      第22回熊本大学医学部附属病院 臨床カンファレンス
    • Place of Presentation
      熊本
  • [Presentation] ヒト化マウスによるヒト疾患解析

    • Author(s)
      山村研一
    • Organizer
      平成25年度「個体レベルでのがん支援活動」ワークショップ 2014(特別講演)
    • Place of Presentation
      琵琶湖ホテル、滋賀県大津市
  • [Presentation] 動物実験における実験結果の信頼性を確保するために‐統御の重要性の再考‐

    • Author(s)
      高倉 彰
    • Organizer
      第47回日本実験動物技術者協会総会シンポジウム
    • Place of Presentation
      岡山
  • [Presentation] J-MICC Study委員会.個別化予防を目指したゲノムコホート研究.

    • Author(s)
      田中英夫、若井建志
    • Organizer
      第20回日本がん予防学会
    • Place of Presentation
      東京
  • [Presentation] 日本人のがん個別化予防の実現に向けたがん分子疫学研究の方向性

    • Author(s)
      田中英夫
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜
  • [Presentation] 日本多施設共同コーホート研究(J-MICC STUDY)の進捗とBBJなどのバイオバンク、ゲノムコーホートとの連携

    • Author(s)
      田中英夫
    • Organizer
      オーダーメイド医療の実現プログラム 平成 25 年度 一般公開シンポジウム
    • Place of Presentation
      東京
  • [Presentation] ゲノムコーホート研究の「倫理的」課題とは?

    • Author(s)
      田中英夫
    • Organizer
      「オーダーメイド医療の実現プログラム」シンポジウム「日本のゲノムコホート研究とバイオバンクの倫理的課題―信頼と責任を考える」
    • Place of Presentation
      東京
  • [Presentation] コンプリヘンシブがパネルと半導体シークエンサーによる千葉J-MICCコホートゲノム解析

    • Author(s)
      三上春夫、永瀬浩喜他
    • Organizer
      第72回日本癌学会
    • Place of Presentation
      パシフィコ横浜
  • [Presentation] 半導体次世代シークエンサーによるリスク集団特異的がん関連遺伝子多型解析

    • Author(s)
      三上春夫、永瀬浩喜他
    • Organizer
      第51回日本癌治療学会
    • Place of Presentation
      国立京都国際会館、京都市
  • [Presentation] Semiconductor-based next-gen sequencing reveals cancer risk-associated genetic variations in Chiba J-MICC cohort study.

    • Author(s)
      J. Katayama, Y. Hayashi, H. Mikami, H. Kageyama, M. Ohira, S. Yokoi, H. Nagase .
    • Organizer
      American Society of Human Genetics
    • Place of Presentation
      Boston Convention & Exhibition Center. Boston, MA USA
  • [Presentation] 基調講演「ゲノム・コホート研究とバイオバンクにおける倫理的配慮とは」

    • Author(s)
      玉腰暁子
    • Organizer
      「オーダーメイド医療の実現化プログラム」シンポジウム「日本のゲノムコホート研究とバイオバンクの倫理的課題―信頼と責任を考える」
    • Place of Presentation
      大手町サンケイプラザホール, 東京
  • [Presentation] Secretory mechanism and functions of senescence-associated exosomes

    • Author(s)
      H. Tahara, M. Okada, M. Muneoka and A. Nakamura
    • Organizer
      ISEV 2013
    • Place of Presentation
      Park Plaza Hotel, Boston, MA USA
  • [Presentation] 老化を誘導する核酸抗かん剤にむけた exosome DDSの開発

    • Author(s)
      田原栄俊
    • Organizer
      第29回日本DDS学会学術集会
    • Place of Presentation
      京都テルサ、京都市
  • [Presentation] マイクロ RNA を用いた革新的がん診断・治療

    • Author(s)
      田原栄俊
    • Organizer
      第14 回ホルモンと癌研究会
    • Place of Presentation
      東京大学山上会館、東京都文京区
  • [Presentation] 老化を誘導する抗腫瘍核酸医薬の可能性

    • Author(s)
      田原栄俊
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
  • [Presentation] テロメア・マイクロRNAを用いた次世代健康診断システム

    • Author(s)
      田原栄俊
    • Organizer
      第3回臨床ゲノム医療学会大阪大会
    • Place of Presentation
      大阪大学谷口記念講堂、大阪府吹田市
  • [Presentation] Therapeutic role of microRNAs in cancer and cellular senescence

    • Author(s)
      Hidetoshi Tahara
    • Organizer
      Small RNAs to Stem Cells & Epigenetic Reprogramming Asia-2013 Meeting
    • Place of Presentation
      東京大学山上会館、東京都文京区
  • [Presentation] Proteomic analysis of EV in senescence and cancer

    • Author(s)
      Hidetoshi Tahara
    • Organizer
      ISEV Workshop on EV Proteomics and Lipidomics
    • Place of Presentation
      Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Australia
  • [Presentation] The origin of human cancer

    • Author(s)
      Haruhiko Sugimura
    • Organizer
      101st Indian Science Congress
    • Place of Presentation
      Jammu, India.
  • [Presentation] 乳がんの疫学

    • Author(s)
      永田知里
    • Organizer
      日本医学会シンポジウム
    • Place of Presentation
      東京
  • [Presentation] サンパウロにおけるがんの移民研究

    • Author(s)
      岩崎 基
    • Organizer
      サンパウロ大学医学部主催 Scientific workshop: Non communicable diseases and global health
    • Place of Presentation
      サンパウロ大学、ブラジル
  • [Presentation] EGFRを標的とした大腸癌分子イメージング

    • Author(s)
      宮本佳彦、六車直樹、高山哲治
    • Organizer
      消化管学会
    • Place of Presentation
      東京
  • [Presentation] 大腸発癌におけるACF-SSA/P-cancer sequenceの検証

    • Author(s)
      藤野泰輝、岡本耕一、六車直樹、高山哲治
    • Organizer
      第21回浜名湖シンポジウム
    • Place of Presentation
      アクトシティ浜松コングレスセンター、浜松市
  • [Presentation] ピロール・イミダゾール(PI)ポリアミドを用いた、前立腺癌新規遺伝子治療薬の検討. 第6回ヤングリサーチグラント受賞者記念講演

    • Author(s)
      大日方大亮
    • Organizer
      第101回日本泌尿器科学会総会
    • Place of Presentation
      札幌
  • [Presentation] ピロール・イミダゾール(PI)ポリアミドを用いた、前立腺癌新規遺伝子治療薬の開発

    • Author(s)
      大日方大亮,藤原恭子,伊藤亜希子,村田保貴,芦苅大作,山口健哉,高山賢一,浦野友彦,藤村哲也,福田 昇,永瀬浩喜, 相馬正義,井上 聡,高橋 悟
    • Organizer
      第14回ホルモンと癌研究会
    • Place of Presentation
      東京
  • [Presentation] 前立腺癌特異的融合遺伝子TMPRSS2-ERG の生成を抑制するピロール・イミダゾール(PI)ポリアミドの開発

    • Author(s)
      大日方大亮,藤原恭子,高山賢一,浦野友彦,永瀬浩喜,相馬正義,井上 聡,高橋 悟
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      東京
  • [Presentation] デュタステリド投与中のPSA管理に関する考察~5ARIはPCaの診断に影響を及ぼすのか~

    • Author(s)
      高橋 悟
    • Organizer
      第65回西日本泌尿器科学会総会
    • Place of Presentation
      佐賀
  • [Presentation] The efficacy of Pyrrole-imidazole (PI) polyamide targeted to TMPRSS2 and ERG gene fusion for prostate cancer

    • Author(s)
      Obinata D, Fujiwara K, Takayama K, Urano T, Nagase H, Fukuda N, Soma M, Inoue S, Takahashi S.
    • Organizer
      The 18th Korea-Japan Cancer Research Workshop
    • Place of Presentation
      Gifu
  • [Presentation] State-of-the-art lecture「proPSA:新規腫瘍マーカーとしての臨床応用への期待(座長)

    • Author(s)
      高橋 悟
    • Organizer
      第21回日本がん検診・診断学会
    • Place of Presentation
      前橋
  • [Presentation] Immunological control of HTLV-1: Prospective therapy towards prophylaxis of disease.

    • Author(s)
      Kannagi M. Hasegawa A, Suehiro Y, Takamori A, Kinpara S, Ando S, Utsunomiya A, Choi I, Uike N.
    • Organizer
      第3回HTLV-1国際シンポジウム
    • Place of Presentation
      東京
    • Invited
  • [Presentation] HTLV-1感染者におけるATL発症予防の展望

    • Author(s)
      神奈木真理
    • Organizer
      ATLシンポジウムin沖縄2014
    • Place of Presentation
      沖縄市民会館、沖縄市
    • Invited
  • [Presentation] HTLV-1感染の免疫学

    • Author(s)
      神奈木真理
    • Organizer
      日本HTLV-1学会設立記念シンポジウム
    • Place of Presentation
      東京
  • [Presentation] HTLV-1から学ぶウイルスと宿主免疫の攻防

    • Author(s)
      神奈木真理
    • Organizer
      第2回日本移植学会若手育成教育セミナー
    • Place of Presentation
      東京
  • [Presentation] ヒトT細胞白血病ウイルス1型の生き残り戦略と病原性

    • Author(s)
      松岡雅雄
    • Organizer
      桜山学術セミナー
    • Place of Presentation
      名古屋市立大学病院10階第4会議室,名古屋.
  • [Presentation] ヒトT細胞白血病ウイルス1型の病原性発現機構と治療戦略

    • Author(s)
      松岡雅雄
    • Organizer
      第17回日本がん分子標的治療学会学術集会ランチョンセミナー1
    • Place of Presentation
      国立京都国際会館第1会場、京都
  • [Presentation] ATL発症と病態の分子基盤解明の試み

    • Author(s)
      渡邉俊樹
    • Organizer
      第11回東海リンパ腫フォーラム学術講演会
    • Place of Presentation
      ホテルキャッスルプラザ、名古屋
    • Invited
  • [Presentation] ATL多段階発癌の分子機構解明へのアプローチ

    • Author(s)
      渡邉俊樹
    • Organizer
      第1回ATL疾患検討会
    • Place of Presentation
      東京コンファレンスセンター・有明、東京
    • Invited
  • [Presentation] 診断と治療法開発につながるATLの分子病態解明の試み

    • Author(s)
      渡邉俊樹
    • Organizer
      長崎県産婦人科学会地方会
    • Place of Presentation
      島原、長崎
    • Invited
  • [Presentation] HTLV-1総合対策3年目の現状

    • Author(s)
      渡邉俊樹
    • Organizer
      長崎県ATLウイルス母子感染防止に関する講習会
    • Place of Presentation
      長崎県医師会館、長崎
    • Invited
  • [Presentation] 「がんの分子病態に基づいた診断法の開発研究」

    • Author(s)
      醍醐弥太郎
    • Organizer
      生命科学系3分野支援活動合同シンポジウム
    • Place of Presentation
      東京
    • Invited
  • [Presentation] 「がんの分子病態研究に基づいた個別化医療開発」

    • Author(s)
      醍醐弥太郎
    • Organizer
      第761回千葉県がんセンター研究所集談会
    • Place of Presentation
      千葉
  • [Presentation] 「ヒトがん関連検体試料の提供事業に於ける質の管理」

    • Author(s)
      宮城洋平
    • Organizer
      第60回日本臨床検査医学会学術集会・委員会特別企画4(標準化委員会)
    • Place of Presentation
      神戸国際会議場
  • [Presentation] 「がん関連試料の収集・提供 解析実証研究まで含めた病理学の役割」

    • Author(s)
      宮城洋平
    • Organizer
      第77回日本病理学会東北支部学術集会
    • Place of Presentation
      東北大学
  • [Presentation] エピジェネティクス創薬研究の流れと課題

    • Author(s)
      吉田稔
    • Organizer
      第17回日本がん分子標的治療学会学術集会
    • Place of Presentation
      国立京都国際会館
  • [Presentation] 新規抗がん剤候補物質の標的分子同定法

    • Author(s)
      長田裕之
    • Organizer
      アカデミア発のがん創薬・個別化医療への挑戦
    • Place of Presentation
      東京
  • [Presentation] Lysine-specific demethylases (LSD1, LSD2)によるTFPI2 (tissue factor pathway inhibitor 1)発現の制御

    • Author(s)
      長谷川慎, 佐々木隆造, 水上民夫.
    • Organizer
      第17回日本がん分子標的治療学会学術集会
    • Place of Presentation
      京都
  • [Presentation] 肝芽腫メチル化解析による予後予測マーカーの確立

    • Author(s)
      本多昌平
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜
  • [Presentation] 次世代シーケンサーを用いた肝芽腫のメチル化解析による予後予測マーカー確立の試み

    • Author(s)
      本多昌平
    • Organizer
      第55回日本小児血液・がん学会学術集会
    • Place of Presentation
      福岡
  • [Book] 免疫組織染色の定量法.細胞工学 33(3)2014

    • Author(s)
      藤岡正喜、山野荘太郎、魏 民、鰐渕英機.
    • Total Pages
      316-322
    • Publisher
      学研メディカル秀潤社
  • [Book] Surviving Cancer in Asia: Cross-boundary Cancer Studies, The University of Tokyo Japan-Asian Studies Program Academic Year 2012-20132014

    • Author(s)
      Editors: Akaza H, Kawahara N
    • Total Pages
      83
    • Publisher
      Oxford University Press
  • [Book] IV.リンパ球系 3. 成人T細胞白血病/リンパ腫におけるNF-kB経路の活性化 Annual Review 2014 血液2014

    • Author(s)
      渡邉俊樹
    • Total Pages
      240
    • Publisher
      中外医学社
  • [Book] がん研究読本③2013

    • Author(s)
      がん研究分野の特性等を踏まえた支援活動 総括支援活動班
    • Total Pages
      100
    • Publisher
      文部科学省科学研究費新学術領域研究 がん研究分野の特性等を踏まえた支援活動
  • [Book] 癌と骨 骨転移の病理2013

    • Author(s)
      神田浩明(分担執筆) 松本俊夫、米田俊之編
    • Total Pages
      35-45
    • Publisher
      メディカルレビュー社
  • [Book] 抗CCR4抗体医薬によるT細胞性腫瘍の治療 Annual Review血液20132013

    • Author(s)
      稲垣淳、 石田高司
    • Total Pages
      58-164
    • Publisher
      中外医学社
  • [Book] Human T-cell leukemia virus type 1 and 2. Fields Virology, 6th edition2013

    • Author(s)
      Fujii M and Matsuoka M.
    • Total Pages
      474-1501
    • Publisher
      Lippincott Williams & Wilkins
  • [Book] 成人T細胞性白血病に対する新規治療法 02巻7号2013

    • Author(s)
      石田 高司
    • Total Pages
      1744-1750
    • Publisher
      日本内科学会雑誌
  • [Book] 成人T細胞白血病・リンパ腫に対する同種移植の成績 血液内科2013

    • Author(s)
      宇都宮 與、 石田 高司
    • Total Pages
      781-788
    • Publisher
      科学評論社
  • [Book] 末梢性γδT細胞リンパ腫 日本臨床別冊血液症候群 第2版2013

    • Author(s)
      森 芙美子, 石田 高司
    • Total Pages
      409-413
    • Publisher
      日本臨牀社
  • [Book] ヒト化抗CCR4抗体モガムリズマブのT細胞リンパ腫への臨床応用 腫瘍内科2013

    • Author(s)
      小畑長英, 秋永士朗, 石田高司, 上田龍三
    • Total Pages
      325-331
    • Publisher
      科学評論社
  • [Book] 「次世代シークエンサーを用いた肺がん分子マーカー研究」雑誌 呼吸2013

    • Author(s)
      醍醐弥太郎
    • Total Pages
      901-906
    • Publisher
      一般社団法人 呼吸研究
  • [Book] 特集・制がん剤の分子標的スクリーニング成績 化学療法基盤情報支援班報告-制がん候補物質のスクリーニング成績・第14報-2013

    • Author(s)
      矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明.
    • Total Pages
      1-114ページ
    • Publisher
      癌と化学療法社
  • [Book] 特集・制がん剤の分子標的スクリーニング成績 化学療法基盤支援活動報告-制がん候補物質のスクリーニング成績・第15報2013

    • Author(s)
      矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 馬島哲夫, 水上民夫, 川田学, 長田裕之, 旦慎吾, 松浦正明, 掛谷秀昭, 冨田章弘
    • Total Pages
      116-146ページ
    • Publisher
      癌と化学療法社
  • [Book] 次世代がん戦略研究Update がん基盤生物学 -革新的シーズ育成に向けて- (執筆タイトル:リン酸化依存性タンパク質間相互作用阻害物質の探索と抗がん剤への展開)2013

    • Author(s)
      渡邉信元, 長田裕之.
    • Total Pages
      336ページ
    • Publisher
      南山堂
  • [Book] 抗がん薬の臨床薬理(分担:抗がん薬のスクリーニング)2013

    • Author(s)
      水上民夫
    • Total Pages
      2-13
    • Publisher
      南山堂
  • [Remarks] 文部科学省科学研究費新学術領域研究 がん研究分野の特性等を踏まえた支援活動

    • URL

      http://ganshien.umin.jp/index.html

  • [Remarks] 「生命科学系3分野支援活動」の助成による日本多施設共同コーホート研究(ジェイミック スタディ)

    • URL

      http://www.jmicc.com/

  • [Remarks] がん研究分野の特性等を踏まえた支援活動 化学療法基盤支援活動

    • URL

      http://scads.jfcr.or.jp/

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Published: 2015-05-28  

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