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Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas

Research Project

Project Areaがん研究分野の特性等を踏まえた支援活動
Project/Area Number 221S0001
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Research InstitutionThe University of Tokyo

Principal Investigator

IMAI Kohzoh (2012-2015)  東京大学, 医科学研究所, 特任研究員 (60117603)

中村 祐輔 (2010-2011)  東京大学, 医科学研究所, 教授 (70217909)

Co-Investigator(Kenkyū-buntansha) INOUE Junichiro  東京大学, 医科学研究所, 教授 (70176428)
NAKAMURA Takuro  公益財団法人がん研究会, がん研究所, 副所長 (00180373)
ISHIKAWA Fuyuki  京都大学, 大学院生命科学研究科, 教授 (30184493)
YAMAMURA Kenichi  熊本大学, 生命資源研究・支援センター, シニア教授 (90115197)
ARAKI Kimi  熊本大学, 生命資源研究・支援センター, 教授 (90211705)
YAO Ryouji  公益財団法人がん研究会, がん研究所 細胞生物部, 主任研究員 (80291095)
TAKANO Hiroshi  公益財団法人がん研究会, がん研究所 細胞生物部, 特任研究員 (00241555)
TAKAKURA Akira  公益財団法人実験動物中央研究所, ICLASモニタリングセンター, 事業部門長 (60167484)
KATOH Hideki  浜松医科大学, 医学部附属動物実験施設, 准教授 (30142053)
NAKAGATA Naomi  熊本大学, 生命資源研究支援センター, 教授 (30159058)
TOYOKUNI Shinya  名古屋大学, 大学院医学系研究科, 教授 (90252460)
WANIBUCHI Hideki  大阪市立大学, 大学院医学研究科, 教授 (90220970)
OGAWA Katsuhiro  旭川医科大学, 医学部, 名誉教授 (50045514)
MITSUMORI Kunitoshi  東京農工大学, 農学研究院, 教授 (10239296)
YAMADA Yasuhiro  京都大学, iPS細胞研究所, 教授 (70313872)
SHIBUTANI Makoto  東京農工大学, 大学院農学研究院, 教授 (20311392)
IMAIDA Katsumi  香川大学, 医学部, 教授 (90160043)
FUTAKUCHI Mitsuru  名古屋市立大学, 大学院医学研究科, 准教授 (60275120)
KANDA Hiroaki  公益財団法人がん研究会, がん研究所 病理部, 主任研究員 (90260067)
TANAKA Hideo  愛知県がんセンター研究所, 疫学・予防部, 部長 (60470168)
WAKAI Kenji  名古屋大学, 大学院医学系研究科, 教授 (50270989)
MIKAMI Haruo  千葉県がんセンター(研究所), がん予防センター, 部長 (10332355)
SUZUKI Sadao  名古屋市立大学, 大学院医学研究科, 教授 (20226509)
MIURA Katsuyuki  滋賀医科大学, 医学部, 教授 (90257452)
WATANABE Yoshiyuki  京都府立医科大学, 大学院医学研究科, 教授 (00191809)
ARISAWA Kokichi  徳島大学, 大学院医歯薬学研究部, 教授 (30203384)
TANAKA Keitaro  佐賀大学, 医学部, 教授 (50217022)
TAKEZAKI Toshiro  鹿児島大学, 大学院医歯学総合研究科, 教授 (50227013)
FURUSHO Norihiro  九州大学, 大学院医学研究院, 准教授 (10346786)
NAITO Mariko  名古屋大学, 大学院医学系研究科, 准教授 (10378010)
OHNAKA Keizo  九州大学, 医学研究院, 講師 (30325518)
KITA Yoshikuni  敦賀市立看護大学, 看護学部, 准教授 (30147524)
KURIKI Kiyonori  静岡県立大学, 食品栄養科学部, 准教授 (20543705)
TAMAKAOSHI Akiko  北海道大学, 大学院医学研究科, 教授 (90236737)
EGUCHI Hidetaka  埼玉医科大学, 医学部, 准教授 (00260232)
KUBO Michiaki  国立研究開発法人理化学研究所, 統合生命医科学研究センター, 副センター長 (30442958)
HAMAJIMA Nobuyuki  名古屋大学, 大学院医学系研究科, 教授 (30172969)
NAGATA Chisato  岐阜大学, 大学院医学系研究科, 教授 (30283295)
HINO Okio  順天堂大学, 医学部, 教授 (90127910)
TAHARA Hidetoshi  広島大学, 大学院医歯薬保健学研究院, 教授 (00271065)
SUGIMURA Haruhiko  浜松医科大学, 医学部, 教授 (00196742)
TSUGANE Shoichiro  国立研究開発法人国立がん研究センター, がん予防・検診研究センター, センター長 (40179982)
NAKATOCHI Masahiro  名古屋大学, 医学部附属病院, 病院助教 (10559983)
TAKAYAMA Tetsuji  徳島大学, 大学院医歯薬学研究部, 教授 (10284994)
AKAZA Hideyuki  東京大学, 情報学環, 特任教授 (70010486)
TAKAHASHI Satoru  日本大学, 医学部, 教授 (50197141)
TSUKAMOTO Taiji  札幌医科大学, 医学部, 教授 (50112454)
NAITO Seiji  九州大学, 大学院医学研究院, 教授 (40164107)
MASUMORI Naoya  札幌医科大学, 医学部, 教授 (20295356)
YOKOMIZO Akira  九州大学, 大学院医学研究院, 准教授 (60346781)
NAMIKI Mikio  金沢大学, 医学系, 教授 (70155985)
FUJIMOTO Kiyohide  奈良県立医科大学, 医学部, 教授 (50264867)
FUJIOKA Tomoaki  岩手医科大学, 医学部, 教授 (80173409)
HORIE Shigeo  順天堂大学, 大学院医学系研究科, 教授 (40190243)
MORI Mitsuru  札幌医科大学, 医学部, 教授 (50175634)
MORIWAKI Hisataka  岐阜大学, 大学院医学系研究科, 教授 (50174470)
Shimizu Masahito  岐阜大学, 大学院医学系研究科, 教授 (90402198)
KANNAGI Mari  東京医科歯科大学, 大学院医歯学総合研究科, 教授 (80202034)
ISHIDA Takashi  名古屋市立大学, 大学院医学研究科, 准教授 (80405183)
MATSUOKA Masao  京都大学, ウイルス研究所, 教授 (10244138)
YAMAOKA Shoji  東京医科歯科大学, 大学院医歯学総合研究科, 教授 (90263160)
TANAKA Yuetsu  琉球大学, 大学院医学研究科, 教授 (30163588)
WATANABE Toshiki  東京大学, 大学院新領域創成科学研究科, 教授 (30182934)
YASUI Hiroshi  東京大学, 医科学研究所, 特任准教授 (40448593)
TSUCHIYA Eiju  湯沢町保健医療センター, 特任研究員 (00072314)
DAIGO Yataro  東京大学, 医科学研究所, 特任教授 (30345029)
MIYAGI Yohei  地方独立行政法人神奈川県立病院機構, 神奈川県立がんセンター・臨床研究所, 総括部長 (00254194)
TAKAHASHI Takashi  名古屋大学, 大学院医学系研究科, 教授 (50231395)
YAMORI Takao  公益財団法人がん研究会, がん化学療法センター, 部長 (60200854)
SEIMIYA Hiroyuki  公益財団法人がん研究会, がん化学療法センター分子生物治療研究部, 部長 (50280623)
UEHARA Yoshimasa  岩手医科大学, 薬学部, 教授 (50160213)
YOSHIDA Minoru  国立研究開発法人理化学研究所, 吉田化学遺伝学研究室, 主任研究員 (80191617)
IMOTO Masaya  慶應義塾大学, 理工学部, 教授 (60213253)
FUKAZAWA Hidesuke  国立感染症研究所, 真菌部, 室長 (10218878)
KAKEYA Hideaki  京都大学, 大学院薬学研究科, 教授 (00270596)
DAN Shingo  公益財団法人がん研究会, がん化学療法センター分子薬理部, 副部長 (70332202)
TOMIDA Akihiro  公益財団法人がん研究会, がん化学療法センター, 部長 (40251483)
KAWADA Manabu  公益財団法人微生物化学研究会, 微生物化学研究所沼津支所, 支所長 (20300808)
OSADA Hiroyuki  国立研究開発法人理化学研究所, 環境資源科学研究センター, 副センター長 (80160836)
MATSUURA Masaaki  帝京大学, 大学院公衆衛生学研究科, 教授 (40173794)
MIZUKAMI Tamio  長浜バイオ大学, バイオサイエンス学部, 教授 (80367896)
MASHIMA Tetsuo  公益財団法人がん研究会, がん化学療法センター分子生物治療研究部, 主任研究員 (30311228)
USHIJIMA Masaru  公益財団法人がん研究会, ゲノムセンター, 研究員 (60328565)
TOKINO Takashi  札幌医科大学, 医学部, 教授 (40202197)
SUZUKI Hiromu  札幌医科大学, 医学部, 教授 (20381254)
SHINOMURA Yasuhisa  札幌医科大学, 医学部, 教授 (90162619)
NOSHO Katsuhiko  札幌医科大学, 医学部, 講師 (10597339)
Co-Investigator(Renkei-kenkyūsha) MIYAZONO Kohei  東京大学, 医学系研究科, 教授 (90209908)
INAZAWA Johji  東京医科歯科大学, 難治疾患研究所, 教授 (30193551)
HIROTA Toru  公益財団法人がん研究会, がん研究所 実験病理部, 部長 (50421368)
NODA Tetsuo  公益財団法人がん研究会, がん研究所, 所長 (10183550)
SUZUKI Misao  熊本大学, 生命資源研究・支援センター, 准教授 (60253720)
TAKEDA Naoki  熊本大学, 生命資源研究・支援センター, 助教 (90304998)
YAGINUMA Katsuyuki  公益財団法人がん研究会, がん研究所 細胞生物部, 研究員 (40182307)
SUGITANI Yoshinobu  公益財団法人がん研究会, がん研究所 細胞生物部, 研究員 (80360569)
ITO Hidemi  愛知県がんセンター研究所, 疫学・予防部, 室長 (90393123)
HOSONO Satoyo  愛知県がんセンター研究所, 疫学・予防部, 主任研究員 (80402600)
IWASAKI Motoki  独立行政法人国立がん研究センター, がん予防・検診研究センター, 室長 (60392338)
NAGASE Hiroki  千葉県がんセンター研究所, がん遺伝創薬研究室, 研究所長 (90322073)
NISHITA Hiroki  札幌医科大学, 医学部, 特任助教 (40531257)
KONO Suminori  九州大学, 大学院医学研究院, 教授 (70128015)
HASHIMOTO Syuji  藤田保健衛生大学, 医学部衛生学講座, 教授 (50148334)
YAMAGUCHI Kazunari  熊本大学, 発生医学研究所, 特別研究員 (20128325)
TAKANO Atsushi  東京大学, 医科学研究所, 特任講師 (50582607)
TERAMOTO Koji  滋賀医科大学, 医学部, 特任講師 (10452244)
MATSUDA Koichi  東京大学, 大学院新領域創成科学研究科, 教授 (90401257)
TANAKA Yukichi  神奈川県立こども医療センター, 臨床研究所, 所長 (50420691)
AOKI Ichiro  横浜市立大学, 大学院医学研究科, 教授 (00184028)
OSAMURA Yoshiyuki  国際福祉大学三田病院, 病理診断センター, センター長 (10100992)
NAKAMURA Naoya  東海大学, 医学部, 教授 (50227922)
SUZUKI Noboru  聖マリアンナ医科大学, 医学部, 教授 (40235982)
TAJIRI Michihiko  神奈川県立循環器呼吸器病センター, 呼吸器外科, 部長 (00449117)
KAWASAKI Takashi  新潟県立がんセンター新潟病院, 病理部, 部長 (20377188)
YOKOSE Tomoyuki  神奈川県立がんセンター, 病理診断科, 部長 (10221665)
YANAGISAWA Kiyoshi  名古屋大学, 大学院医学系研究科, 講師 (20372112)
HIRAKAWA Akihiro  名古屋大学, 医学部附属病院先端医療・臨床研究支援センター, 講師 (90609330)
IIJIMA Yoshihiko  名古屋大学, 大学院医学系研究科, 特任准教授 (50584679)
ZEMBUTSU Hitoshi  東京大学, 医科学研究所, 助教 (90372820)
SASAKI Yasushi  札幌医科大学, 医学部フロンティア医学研究所, 准教授 (70322328)
IDOGAWA Masashi  札幌医科大学, 医学部フロンティア医学研究所, 講師 (00404749)
MARUYAMA Reo  札幌医科大学, 医学部分子生物学講座, 准教授 (60607985)
KAI Masahiro  札幌医科大学, 医学部分子生物学講座, 講師 (80260777)
Project Period (FY) 2010-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Keywords若手支援 / 国際研究者交流 / 遺伝子改変マウス / 病理形態学 / ゲノムコーホート研究 / 次世代分子解析技術 / アカデミア創薬 / ゲノム・エピゲノム解析支援 / 個別化がん予防 / 国際交流 / ATL発症予防 / 分子疫学コーホート研究 / がん化学予防 / ATL発がん機序 / ATL発症リスク / がん分子標的薬剤
Outline of Final Research Achievements

We started this project first supporting scientists who aim to overcome cancer, and from 2014 we extended our support to scientists in life sciences. The outcome has been as follows: General Support Group fostered young scientists and those who will be involved in research support in the future, and developed international academic exchanges. Our support services such as providing genetically modified mice and providing bioresources including cancer tissues enabled many scientists to conduct international and cutting-edge researches. All Japan Cohort Group and ATL Study Group (originated in Japan) collected more than 110,000 important samples and contributed for many scientists to produce their results. Chemotherapy Group and Genome and Epigenome Group also achieved more than their original goals. Further, we organized open lectures for general public to inform the importance of scientific support.

Report

(7 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • 2010 Annual Research Report

Research Products

(1534 results)

All 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Int'l Joint Research (6 results) Journal Article (765 results) (of which Int'l Joint Research: 26 results,  Peer Reviewed: 756 results,  Open Access: 183 results,  Acknowledgement Compliant: 187 results) Presentation (640 results) (of which Int'l Joint Research: 30 results,  Invited: 111 results) Book (66 results) Remarks (43 results) Patent(Industrial Property Rights) (14 results) (of which Overseas: 2 results)

  • [Int'l Joint Research] ハルビン医科大学/南京大学 (中国)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] Tufts大学/Medical University of South Carolina/University of Hawaii Cancer Center(米国)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] University of Medicine and Pharmacy(ルーマニア)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] Maria Sklodowska-Curie Memorial Cancer C(ポーランド)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] University of Alberta(カナダ)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research]

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Matrix metalloproteinase 9 gene polymorphisms are associated with a multiple family history of gastric cancer2017

    • Author(s)
      Okada R, Naito M, Hattori Y, Seiki T, Wakai K, Nanri H, Watanabe M, Suzuki S, Kairupan T, Takashima N, Mikami H, Ohnaka K, Watanabe Y, Katsuura-Kamano S, Kubo M, Hamajima N, Tanaka H, The J-MICC Study Group.
    • Journal Title

      Gastric Cancer

      Volume: ahead of print Pages: 246-253

    • DOI

      10.1007/s10120-016-0608-2

    • NAID

      40021129395

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Report of the Japan diabetes society/Japanese cancer association joint committee on diabetes and cancer, Second report.2016

    • Author(s)
      Goto A, Noto H, Noda M, Ueki K, Kasuga M, Tajima N, Ohashi K, Sakai R, Tsugane S, Hamajima N, Tajima K, Imai K, Nakagama H.
    • Journal Title

      Cancer Science

      Volume: 107(3) Issue: 3 Pages: 369-371

    • DOI

      10.1111/cas.12889

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Report of the Japan Diabetes Society (JDS)/Japanese Cancer Association (JCA) Joint Committee on Diabetes and Cancer, Second Report2016

    • Author(s)
      Goto A, Noto H, Noda M, Ueki K, Kasuga M, Tajima N, Ohashi K, Sakai R, Tsugane S, Hamajima N, Tajima K, Imai K, Nakagama H.
    • Journal Title

      Diabeto Int.

      Volume: 7 Pages: 12-15

    • DOI

      10.1007/s13340-016-0257-z

    • NAID

      130005142004

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association of Fusobacterium nucleatum with immunity and molecular alterations in colorectal cancer.2016

    • Author(s)
      Nosho K, Sukawa Y, Adachi Y, Ito M, Mitsuhashi K, Kurihara H, Kanno S, Yamamoto I, Ishigami K, Igarashi H, Maruyama R, Imai K, Yamamoto H, Shinomura Y.
    • Journal Title

      World J Gastroenterol

      Volume: 22 Pages: 557-566

    • DOI

      10.3748/wjg.v22.i2.557

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The relationship between EZH2 expression and microRNA-31 in colorectal cancer and the role in evolution of the serrated pathway.2016

    • Author(s)
      Kurihara H, Maruyama R, Ishiguro K, Kanno S, Yamamoto I, Ishigami K, Mitsuhashi K, Igarashi H, Ito M, Tanuma T, Sukawa Y, Okita K, Hasegawa T, Imai K, Yamamoto H, Shinomura Y, Nosho K.
    • Journal Title

      Oncotarget

      Volume: 7 Issue: 11 Pages: 12704-120717

    • DOI

      10.18632/oncotarget.7260

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Transgenic mouse model for imaging of interleukin-1β-related inflammation in vivo.2016

    • Author(s)
      Iwawaki T, Akai R, Oikawa D, Toyoshima T, Yoshino M, Suzuki M, Takeda N, Ishikawa T, Kataoka Y, Yamamura K.
    • Journal Title

      Sci. Reports

      Volume: 5 Pages: 17205-17205

    • DOI

      10.1038/srep17205

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Cathepsin D in pancreatic acinar cells is implicated in cathepsin B and L degradation, but not in autophagic activity.2016

    • Author(s)
      Mehanna, S, Suzuki, C., Shibata, M., Sunabori, T., Imanaka, T., Araki, K., Yamamura, K., Uchiyama, Y. and Ohmuraya, M.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 469 Pages: 405-11

    • DOI

      10.1016/j.bbrc.2015.12.002

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Severe ocular phenotypes in Rbp4-deficient mice in the C57BL/6 genetic background.2016

    • Author(s)
      Shen, J., Shi, D., Suzuki, T., Xia, Z., Zhang, H., Araki, K., Wakana, S., Takeda, N., Yamamura, K., Jin, S. and Li. Z.
    • Journal Title

      Laboratory Investigation

      Volume: in press Pages: 1-12

    • DOI

      10.1038/labinvest.2016.39

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] GNAS and Kras cooperate to promote murine pancreatic tumorigenesis recapitulating human intraductal papillary mucinous neoplasm.2016

    • Author(s)
      Taki, K., Ohmuraya, M., Tanji, E., Komatsu, H., Hashimoto, D., Semba, K., Araki, K., Kawaguchi, Y., Baba, H. and Furukawa, T.
    • Journal Title

      Oncogene.

      Volume: in press Pages: 2407-2412

    • DOI

      10.1038/onc.2015.294

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Suppression of Intestinal Tumors by Targeting the Mitotic Spindle of Intestinal Stem Cells2016

    • Author(s)
      Ryoji Yao1,*, Jun Oyanagi1, Yasuko Natsume1, Daisuke Kusama1, Yumi Kato1, Satoshi Nagayama2, Tetsuo Noda1,3
    • Journal Title

      Oncogene

      Volume: in press

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] GANP protein encoded on human chromosome 21/mouse chromosome 10 is associated with resistance to mammary tumor development.2016

    • Author(s)
      Kuwahara K, Yamamoto-Ibusuki M, Zhang Z, Phimsen S, Gondo N, Yamashita H, Takeo T, Nakagata N, Yamashita D, Fukushima Y, Yamamoto Y, Iwata H, Saya H, Kondo E, Matsuo K, Takeya M, Iwase H, Sakaguchi N.
    • Journal Title

      Cancer Science

      Volume: in press Pages: 469-477

    • DOI

      10.1111/cas.12883

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Loss of Folliculin Disrupts Hematopoietic Stem Cell Quiescence and Homeostasis Resulting in Bone Marrow Failure2016

    • Author(s)
      Baba M, Toyama H, Sun L, Takubo K, Suh HC, Hasumi H, Nakamura-Ishizu A, Hasumi Y, Klarmann KD, Nakagata N, Schmidt LS, Linehan WM, Suda T, Keller JR
    • Journal Title

      Stem cells

      Volume: 34 Pages: 1068-1082

    • DOI

      10.1002/stem.2293

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] The origin and future of oxidative stress pathology: From the recognition of carcinogenesis as an iron addiction with ferroptosis-resistance to non-thermal plasma therapy.2016

    • Author(s)
      Toyokuni S.
    • Journal Title

      Pathology Internationa

      Volume: in press Pages: 245-259

    • DOI

      10.1111/pin.12396

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Heterogeneity of tumor cells in the bone microenvironment: mechanisms and therapeutic targets for bone metastasis of prostate or breast cancer2016

    • Author(s)
      Futakuchi M, Fukamachi K, Suzui M.
    • Journal Title

      Adv Drug Deliv Rev

      Volume: 99 Pages: 206-211

    • DOI

      10.1016/j.addr.2015.11.017

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] C5a inhibitor protects ischemia/reperfusion injury in rat small intestine.2016

    • Author(s)
      Tuboly E, Futakuchi M, Varga G, Erces D, Tokes T, Meszaros A, Kaszaki J, Suzui M, Imai M, Okada A, Okada N, Boros M, Okada H.
    • Journal Title

      Microbiol Immunol

      Volume: 60 Pages: 302-309

    • DOI

      10.1111/1348-0421.12338

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] A Diarylpentanoid Curcumin Analog Exhibits Improved Radioprotective Potential in the Intestinal Mucosa2016

    • Author(s)
      Fukuda, K, Uehara, Y, Nakata, E, Inoue, M, Shimazu, K, Yoshida, T, Kanda, H, Nanjo, H, Hosoi, Y, Yamakoshi, H, Iwabuchi, Y, Shibata, H
    • Journal Title

      International Journal of Radiation Biology

      Volume: in press Pages: 388-394

    • DOI

      10.3109/09553002.2016.1164910

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] EWS-FLI1-induced osteosarcoma model unveiled a crucial role of impaired osteogenic differentiation on osteosarcoma development.2016

    • Author(s)
      Komura S, Semi K, Itakura F, Shibata H, Ohno T, Hotta A, Woltjen K, Yamamoto T, Akiyama H, Yamada Y.
    • Journal Title

      Stem Cell Reports.

      Volume: 6(4) Pages: 592-606

    • DOI

      10.1016/j.stemcr.2016.02.009

    • NAID

      120005756300

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Aldehyde dehydrogenase 2 (ALDH2) and alcohol dehydrogenase 1B (ADH1B) polymorphisms exacerbate bladder cancer risk associated with alcohol drinking: Gene-environment interaction.2016

    • Author(s)
      Masaoka H, Ito H, Soga N, Hosono S, Oze I, Watanabe M, Tanaka H, Yokomizo A, Hayashi N, Eto M, Matsuo K.
    • Journal Title

      Carcinogenesis

      Volume: in press Pages: 583-585

    • DOI

      10.1093/carcin/bgw033

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Development of a prediction model and estimation of cumulative risk for upper aerodigestive tract cancer on the basis of the aldehyde dehydrogenase 2 genotype and alcohol consumption in a Japanese population.2016

    • Author(s)
      Koyanagi YN, Ito H, Oze I, Hosono S, Tanaka H, Abe T, Shimizu Y, Hasegawa Y, Matsuo K
    • Journal Title

      Eur J Cancer Prev

      Volume: 印刷中

    • DOI

      10.1097/cej.0000000000000222

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Prognostic Value of Drinking Status and Aldehyde Dehydrogenase 2 Polymorphism in Patients With Head and Neck Squamous Cell Carcinoma2016

    • Author(s)
      Kawakita D, Oze I, Hosono S,Ito H, Watanabe M, Yatabe Y, Hasegawa Y, Murakami S,Tanaka H, Matsuo K.
    • Journal Title

      Journal of Epidemiology

      Volume: ahead of print Issue: 6 Pages: 292-299

    • DOI

      10.2188/jea.je20140240

      10.2188/jea.JE20140240

    • NAID

      130005154812

    • ISSN
      0917-5040, 1349-9092
    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Impact of metallothionein gene polymorphisms on the risk of lung cancer in a Japanese population2016

    • Author(s)
      Nakane H, Hirano M, Ito H, Hosono S, Oze I, Matsuda F, Tanaka H, Matsuo K.
    • Journal Title

      Mol Carcinog

      Volume: 54(S1)

    • DOI

      10.1002/mc.22198

    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] A risk prediction model for colorectal cancer using genome-wide association study-identified polymorphisms and established risk factors among Japanese: results from two independent case-control studies.2016

    • Author(s)
      Hosono S, Ito H, Oze I, Watanabe M, Komori K, Yatabe Y, Shimizu Y, Tanaka H, Matsuo K.
    • Journal Title

      Eur J Cancer Prev

      Volume: 印刷中

    • DOI

      10.1097/cej.0000000000000213

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] A variant of the CLOCK gene and related haplotypes are associated with the prevalence of type 2 diabetes in the Japanese population. Japan Multi-institutional Collaborative Cohort (J-MICC) Study Group.2016

    • Author(s)
      Uemura H, Katsuura-Kamano S, Yamaguchi M, Arisawa K, Hamajima N, Hishida A, Kawai S, Oze I, Shinchi K, Takashima N, Suzuki S, Nakahata N, Mikami H, Ohnaka K, Kuriyama N, Kubo M, Tanaka H.
    • Journal Title

      J Diabetes

      Volume: online

    • DOI

      10.1111/1753-0407.12344

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] The Effects of URAT1/SLC22A12 Nonfunctional Variants, R90H and W258X, on Serum Uric Acid Levels and Gout/hyperuricemia Progression2016

    • Author(s)
      Sakiyama M, Matsuo H, Shimizu S et al.
    • Journal Title

      Sci Rep

      Volume: 6 Pages: 20148-20148

    • DOI

      10.1038/srep20148

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Adjustment of Cell-Type Composition Minimizes Systematic Bias in Blood DNA Methylation Profiles Derived by DNA Collection Protocols.2016

    • Author(s)
      Shiwa Y, Hachiya T, Furukawa R, Ohmomo H, Ono K, Kudo H, Hata J, Hozawa A, Iwasaki M, Matsuda K, Minegishi N, Satoh M, Tanno K, Yamaji T, Wakai K, Hitomi J, Kiyohara Y, Kubo M, Tanaka H, Tsugane S, Yamamoto M, Sobue K, Shimizu A.
    • Journal Title

      PLoS One

      Volume: 6 Pages: 1-16

    • DOI

      10.1371/journal.pone.0147519

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes.2016

    • Author(s)
      Matsuo H, et al.
    • Journal Title

      Annals of the Rheumatic Diseases

      Volume: 印刷中 Pages: 625-659

    • DOI

      10.1136/annrheumdis-2014-206191

    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] ヘリコバクター・ピロリ感染者における慢性萎縮性胃炎の進展に及ぼす因子― 摂取栄養素分析による検討2016

    • Author(s)
      瀬古千佳子,松井大輔,松川泰子,小山晃英,渡邉功,尾﨑悦子,栗山長門,水野成人,渡邊 能行
    • Journal Title

      日本消化器がん検診学会雑誌

      Volume: 54 Pages: 30-41

    • NAID

      130005123140

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ペプシノゲン法によって判定した萎縮性胃炎の背景因子の検討2016

    • Author(s)
      松川泰子, 瀬古千佳子, 松井大輔, 渡邉功, 小山晃英, 尾﨑悦子, 栗山長門, 水野成人, 渡邊 能行
    • Journal Title

      日本消化器がん検診学会雑誌

      Volume: 54 Pages: 248-258

    • NAID

      130005144315

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] "Influence of cigarette smoking and inflammatory gene polymorphisms on glycated hemoglobin in the Japanese general population"2016

    • Author(s)
      Nishida Y, Hara M, Sakamoto T, Shinchi K, Kawai S, Naito M, Hamajima N, Kadota A, Suzuki S, Ibusuki R, Hirata A, Yamaguchi M, Kuriyama N, Oze I, Mikami H, Kubo M, Tanaka H.
    • Journal Title

      Prev Med Rep

      Volume: 3 Pages: 288-295

    • DOI

      10.1016/j.pmedr.2016.03.010

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Validity of a food frequency questionnaire in a population with high alcohol consumption in Japan.2016

    • Author(s)
      Nakahata NT, Takada AN, Imaeda N, Goto C, Kuwabara KH, Niimura H, Arai Y, Yoshita K, Takezaki T
    • Journal Title

      Asia Pac J Clin Nutr

      Volume: 25 Pages: 195-201

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Positive Association of Plasma Homocysteine Levels with Cardio-Ankle Vascular Index in a Prospective Study of Japanese Men from the General Population2016

    • Author(s)
      Mantjoro EM, Toyota K, Kanouchi H, Kheradmand M, Niimura H, Kuwabara K, Nakahata N, Ogawa S, Shimatani K, Kairupan TS, Nindita Y, Ibusuki R, Nerome Y, Owaki T, Maenohara S, Takezaki T
    • Journal Title

      J Atheroscler Thromb

      Volume: ahead of print Issue: 6 Pages: 681-691

    • DOI

      10.5551/jat.32243

    • NAID

      130005154755

    • ISSN
      1340-3478, 1880-3873
    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] A thymine-adenine dinucleotide repeat polymorphism near IL28B is associated with spontaneous clearance of hepatitis C virus.2016

    • Author(s)
      Hiramine S, Sugiyama M, Furusyo N, Uto H, Ido A, Tsubouchi H, Watanabe H, Ueno Y, Korenaga M, Murata K, Masaki N, Hayashi J, Thomas DL, Mizokami M.
    • Journal Title

      Journal of Gastroenterology

      Volume: 50 Pages: 1069-1077

    • DOI

      10.1007/s00535-015-1056-1

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] The relation of postprandial plasma glucose and serum endostatin to the urinary albumin excretion of residents with prediabetes: results from the Kyushu and Okinawa Population Study (KOPS)2016

    • Author(s)
      Shimizu M, Furusyo N, Tanaka Y, Kato Y, Mitsumoto-Kaseida F, Takayama K, Ura K, Hiramine S, Hayashi T, Ikezaki H, Ihara T, Mukae H, Ogawa E, Toyoda K, Kainuma M, Murata M, Hayashi J
    • Journal Title

      Int Urol Nephrol

      Volume: ahead of print

    • DOI

      10.1007/s11255-016-1258-3

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Positive linear dose-response relationships, but no J-shaped relationship, between drinking habits and estimated glomerular filtration rate in middle-aged Japanese men.2016

    • Author(s)
      Shirai Y, Kuriki K, Endoh K, Miyauchi R, Kasezawa N, Tohyama K, Goda T.
    • Journal Title

      Alcohol

      Volume: 51 Pages: 71-7

    • DOI

      10.1016/j.alcohol.2015.12.004

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Changes of tryptophan metabolism in Japanese runners during an ultramarathon race.2016

    • Author(s)
      Yamada N, Shibata K, Fuku M, Kuriki K, Goto G, Tokudome Y, Miyata M, Maeda K, Hoshino H, Suzuki S, Marumoto M, Ichikawa H, Agawa H, Ishikawa N, Arakawa K, Hosono A, Kobayashi M, Tokudome S.
    • Journal Title

      Sport Sci Health

      Volume: 12 Pages: 77-83

    • DOI

      10.1007/s11332-016-0257-1

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rapid detection of germline mutations for hereditary gastrointestinal polyposis/cancers using HaloPlex target enrichment and high-throughput sequencing technologies.2016

    • Author(s)
      Kohda M, Kumamoto K, Eguchi H, Hirata T, Tada Y, Tanakaya K, Akagi K, Takenoshita S, Iwama T, Ishida H, Okazaki Y.
    • Journal Title

      Fam Cancer

      Volume: ahead of print

    • DOI

      10.1007/s10689-016-9872-x

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Identification of a Japanese Lynch syndrome patient with large deletion in the 3' region of the EPCAM gene.2016

    • Author(s)
      Eguchi H, Kumamoto K, Suzuki O, Kohda M, Tada Y, Okazaki Y, Ishida H.
    • Journal Title

      Jpn J Clin Oncol

      Volume: 46 Pages: 178-184

    • DOI

      10.1093/jjco/hyv172

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Lower prevalence of Lynch syndrome in colorectal cancer patients in a Japanese hospital-based population.2016

    • Author(s)
      Kumamoto K, Ishida H, Suzuki O, Tajima Y, Chika N, Kuwabara K, Ishibashi K, Saito K, Nagata K, Eguchi H, Tamaru J, Iwama T.
    • Journal Title

      Surg Today

      Volume: ahead of print

    • DOI

      10.1007/s00595-015-1232-1

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinical impacts of mesothelin expression in gastrointestinal carcinomas.2016

    • Author(s)
      Einama T., Kawamata F., Kamachi H., Nishihara H., Homma S., Matsuzawa F., Mizukami T., Konishi Y., Tahara M., Kamiyama T., Hino O., Taketomi A., Todo S.
    • Journal Title

      World J. Gastrointestinal Pathophysiology

      Volume: in press

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] MicroRNA-203 Suppresses Invasion and Epithelial-mesenchymal Transition Induction via Targeting NUAK1 and SNAI2 in Head and Neck Cancer2016

    • Author(s)
      Obayashi, M., Yoshida, M., Tsunematsu, T., Ogawa, I., Sasahira, T., Kuniyasu, H., Imoto, I., Abiko, Y., Xu, D., Fukunaga, S., Tahara, H., Kudo, Y., Nagao, T., Takata, T.
    • Journal Title

      Oncotarget.

      Volume: 6972 Pages: 8223-39

    • DOI

      10.18632/oncotarget.6972

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Genetic Polymorphisms of <i>CYP2A6</i> in a Case-Control Study on Bladder Cancer in Japanese Smokers2016

    • Author(s)
      Kumondai M, Hosono H, Orikasa K, Yoichi A, Sugimura H, Ozono S, Sugiyama T, Takayama T, Sasaki T, Hirasawa N, Hiratsuka M
    • Journal Title

      Biol. Pharm. Bull.

      Volume: 39 Issue: 1 Pages: 84-89

    • DOI

      10.1248/bpb.b15-00604

    • NAID

      130005116502

    • ISSN
      0918-6158, 1347-5215
    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Functional Evaluation of Nine Missense-Type Variants of the Human DNA Glycosylase Enzyme MUTYH in the Japanese Population.2016

    • Author(s)
      Shinmura K, Kato H, Goto M, Yamada H, Tao H, Nakamura S, Sugimura H.
    • Journal Title

      Human Mutation

      Volume: 37 Pages: 350-353

    • DOI

      10.1002/humu.22949

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Uterine Angiosarcoma: A Case Report and Literature Review.2016

    • Author(s)
      Liu Y, Guo S, Wang L, Suzuki S, Sugimura H, Li Y.
    • Journal Title

      Int J Gynecol Pathol.

      Volume: 35(3) Pages: 264-268

    • DOI

      10.1097/pgp.0000000000000219

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Clinical significance of PDL1 and PDL2 copy number gains in nonsmallcell lung cancer2016

    • Author(s)
      Inoue Y, Yoshimura K, Mori K, Kurabe N, Kahyo T, Mori H, Kawase A, Tanahashi M, Ogawa H, Inui N, Funai K, Shinmura K, Niwa H, Suda T, Sugimura H
    • Journal Title

      Oncotarget

      Volume: 印刷中

    • DOI

      10.18632/oncotarget.8528

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Immunohistochemical features and staging of early gastric cancer2016

    • Author(s)
      Gurzu S, orlowska J, Sugimura H, Bara T, Szentirmay Z, Januszewicz W, Bara TJ, Szederjesi J, Jung I
    • Journal Title

      Arch Med Sci

      Volume: in press

    • DOI

      10.5114/aoms.2016.58665

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Association of Fusobacterium nucleatum with clinical and molecular features in colorectal serrated pathway.2015

    • Author(s)
      Ito M, Kanno S, Nosho K, Sukawa Y, Mitsuhashi K, Kurihara H, Igarashi H, Takahashi T, Tachibana M, Takahashi H, Yoshii S, Takenouchi T, Hasegawa T, Okita K, Hirata K, Maruyama R, Suzuki H, Imai K, Yamamoto H, Shinomura Y.
    • Journal Title

      Int J Cancer

      Volume: 137 Pages: 1258-1268

    • DOI

      10.1002/ijc.29488

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Establishment of patient-derived cancer xenografts in immunodeficient NOG mice.2015

    • Author(s)
      Chijiwa T, Kawai K, Noguchi A, Sato H, Hayashi A, Cho H, Shiozawa M, Kishida T, Morinaga S, Yokose T, Katayama M, Takenaka N, Suemizu H, Yamada R, Nakamura Y, Ohtsu T, Takano Y, Imai K, Miyagi Y, Nakamura M
    • Journal Title

      Internatinal Journal of Oncology

      Volume: 47 Pages: 61-70

    • DOI

      10.3892/ijo.2015.2997

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Epigenetic silencing of NTSR1 is associated with lateral and noninvasive growth of colorectal tumors2015

    • Author(s)
      Kamimae S, Yamamoto E, Kai M, Niinuma T, Yamano HO, Nojima M, Yoshikawa K, Kimura T, Takagi R, Harada E, Harada T, Maruyama R, Sasaki Y, Tokino T, Shinomura Y, Sugai T, Imai K, Suzuki H
    • Journal Title

      Oncotarget.

      Volume: 6 Pages: 29975-29990

    • DOI

      10.18632/oncotarget.5034

    • NAID

      130005161526

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Association of microRNA-31-5p with clinical efficacy of anti-EGFR therapy in patients with metastatic colorectal cancer2015

    • Author(s)
      Igarashi H, Kurihara H, Mitsuhashi K, Ito M, Okuda H, Kanno S, Naito T, Yoshii S, Takahashi H, Kusumi T, Hasegawa T, Sukawa Y, Adachi Y, Okita K, Hirata K, Imamura Y, Baba Y, Imai K, Suzuki H, Yamamoto H, Nosho K, Shinomura Y
    • Journal Title

      Annals of Surgical Oncology

      Volume: 14 Pages: 2640-2648

    • DOI

      10.1245/s10434-014-4264-7

    • Description
      Epub ahead of print
    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Low-frequency IL23R coding variant associated with Crohn's disease susceptibility in Japanese subjects identified by personal genomics analysis2015

    • Author(s)
      Onodera K, Arimura Y, Isshiki H, Kawakami K, Nagaishi K, Yamashita K, Yamamoto E, Niinuma T, Naishiro Y, Suzuki H, Imai K, Shinomura Y
    • Journal Title

      Plos One

      Volume: 10

    • DOI

      10.1371/journal.pone.0137801

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Analysis of the molecular features of rectal carcinoid tumors to identify new biomarkers that predict biological malignancy2015

    • Author(s)
      Mitsuhashi K, Yamamoto I, Kurihara H, Kanno S, Ito M, Igarashi H, Ishigami K, Sukawa Y, Tachibana M, Takahashi H, Tokino T, Maruyama R, Suzuki H, Imai K, Shinomura Y, Yamamoto H, Nosho K
    • Journal Title

      Oncotarget

      Volume: 6 Pages: 22114-22125

    • DOI

      10.18632/oncotarget.4294

    • NAID

      130005161488

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Role of interleukin-32 in the mechanism of chronic inflammation in IgG4-related disease and as a predictive biomarker for drug-free remission.2015

    • Author(s)
      Shimizu Y, Yamamoto M, Yajima H, Suzuki C, Naishiro Y, Takahashi H, Imai K, Shinomura Y.
    • Journal Title

      Modern Rheumatology

      Volume: 26(3) Pages: 391-7

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Everyday clinical practice in IgG4-related dacryoadenitis and/or sialadenitis: Results from the SMART database.2015

    • Author(s)
      Yamamoto M, Yajima H, Takahashi H, Yokoyama Y, Ishigami K, Shimizu Y, Tabeya T, Suzuki C, Naishiro Y, Takano KI, Yamashita K, Hashimoto M, Keira Y, Honda S, Abe T, Suzuki Y, Mukai M,Himi T, Hasegawa T, Imai K, Shinomura Y
    • Journal Title

      Modern Rheumatology

      Volume: 27 Pages: 199-204

    • DOI

      10.3109/14397595.2014.950036

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Schwann cells contribute to neurodegeneration of transthyretin amyloidosis.2015

    • Author(s)
      Murakami T, Sango K, Watabe K, Niimi N, Takaku S, Li Z, Yamamura K, Sunada Y.
    • Journal Title

      Journal of Neurochemistry

      Volume: 134 Pages: 66-74

    • DOI

      10.1111/jnc.13068

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] CHF5074 (CSP-1103) stabilizes human transthyretin in mice humanized at the transthyretin and retinol-binding protein loci.2015

    • Author(s)
      Mu, Yanshuang; Jin, Shoude; Shen, Jingling; Sugano, Aki; Takaoka, Yutaka; Qiang, Lixia; Imbimbo, Bruno P; Yamamura, Ken-Ichi; Li, Zhenghua
    • Journal Title

      FEBS Lett.

      Volume: 589 Pages: 849-856

    • DOI

      10.1016/j.febslet.2015.02.020

    • Description
      in press
    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
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  • [Journal Article] Requirement of DLG1 for cardiovascular development and tissue elongation 1 during cochlear, enteric, and skeletal development: possible role in convergent extension.2015

    • Author(s)
      Akiko Iizuka-Kogo, Takao Senda, Tetsu Akiyama, Atsushi Shimomura, Ryuji Nomura, Yoshimi Hasegawa, Ken-ichi Yamamura, Hiroshi Kogo, Nobuhiko Sawai, Toshiyuki Matsuzaki
    • Journal Title

      Plos One

      Volume: 10

    • DOI

      10.1371/journal.pone.0123965

    • Related Report
      2015 Annual Research Report
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  • [Journal Article] Roles of hepatic glucokinase in intertissue metabolic communication: examination of novel liver-specific glucokinase knockout mice2015

    • Author(s)
      Hayashi H
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 印刷中 Pages: 727-732

    • DOI

      10.1016/j.bbrc.2015.03.097

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      2015 Annual Research Report
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  • [Journal Article] SPINK1 Status in Colorectal Cancer, Impact on Proliferation, and Role in Colitis-associated Cancer2015

    • Author(s)
      Ida S, Ozaki N, Araki K, Hirashima K, Zaitsu Y, Taki K, Sakamoto Y, Miyamoto Y, Oki E, Morita M, Watanabe M, Maehara Y, Yamamura KI, Baba H, Ohmuraya M
    • Journal Title

      Molecular Cancer Research

      Volume: 印刷中 Pages: 1130-1138

    • DOI

      10.1158/1541-7786.mcr-14-0581

    • Related Report
      2015 Annual Research Report
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  • [Journal Article] Mechanism for increased hepatic glycerol synthesis in the citrin/mitochondrial glycerol-3-phosphate dehydrogenase double-knockout mouse : Urine glycerol and glycerol 3-phosphate as potential diagnostic markers of human citrin deficiency.2015

    • Author(s)
      Moriyama M, Fujimoto Y, Rikimaru S, Ushikai M, Kuroda E, Kawabe K, Takano K, Asakawa A, Inui A, Eto K, Kadowaki T, …, Kure S, Mitsubuchi H, Endo F, Horiuchi M, Nakamura Y, Yamamura K, Saheki T
    • Journal Title

      BBA Molecular Basis of Disease

      Volume: 印刷中 Pages: 1787-1795

    • DOI

      10.1016/j.bbadis.2015.04.023

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      2015 Annual Research Report
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  • [Journal Article] Pathophysiological significance of the two-pore domain K(+) channel K2P5.1 in splenic CD4(+)CD25(-) T cell subset from a chemically-induced murine inflammatory bowel disease model.2015

    • Author(s)
      Nakakura S, Matsui M, Sato A, Ishii M, Endo K, Muragishi S, Murase M, Kito H, Niguma H, Kurokawa N, Fujii M, Araki M, Araki K, Ohya S.
    • Journal Title

      Front. Physiol.

      Volume: 6 Pages: 299-299

    • DOI

      10.3389/fphys.2015.00299

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      2015 Annual Research Report
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  • [Journal Article] Meikin is a conserved regulator of meiosis-I-specific kinetochore function2015

    • Author(s)
      Kim, J., Ishiguro, K., Nambu, A., Akiyoshi, B., Yokobayashi, S., Kagami, A., Ishiguro, T., Pendas, A.M., Takeda, N., Sakakibara, Y., Kitajima, T.S., Tanno, Y., Sakuno, T., and Watanabe, Y.
    • Journal Title

      Nature

      Volume: 517 Pages: 466-471

    • DOI

      10.1038/nature14097

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Determining C-Myb protein levels can isolate functional hematopoietic stem cell subtypes.2015

    • Author(s)
      Sakamoto H, Takeda N, Arai F, Hosokawa K, Garcia P, Suda T, Frampton J, Ogawa M
    • Journal Title

      Stem Cells.

      Volume: 33 Pages: 478-490

    • DOI

      10.1002/stem.1855

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      2015 Annual Research Report 2014 Annual Research Report
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  • [Journal Article] Perinatal Gjb2 gene transfer rescues hearing in a mouse model of hereditary deafness.2015

    • Author(s)
      Izuka T., Kamiya K., Gotoh S., Sugitani Y., Suzuki M., Noda T., Minowa O., Ikeda K.
    • Journal Title

      Hum. Mol. Genet.

      Volume: 24)13) Pages: 3651-3661

    • DOI

      10.1093/hmg/ddv109

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Systematic stereoscopic analyses for cloacal development: The origin of anorectal malformations.2015

    • Author(s)
      Matsumaru D, Murashima A, Fukushima J, Senda S, Matsushita S, Nakagata N, Miyajima M, Yamada G.
    • Journal Title

      The origin of anorectal malformations

      Volume: 10;5 Pages: 13943-13943

    • DOI

      10.1038/srep13943

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Cysteine analogs with a free thiol group promote fertilization by reducing disulfide bonds in the Zona Pellucida of mice2015

    • Author(s)
      Takeo, T., Horikoshi, Y., Nakao, S., Sakoh, K., Ishizuka, Y., Tsutsumi, A., Fukumoto, K., Kondo, T., Haruguchi, Y., Takeshita, Y., Nakamuta, Y., Tsuchiyama, S. and Nakagata, N.
    • Journal Title

      Biology of Reproduction

      Volume: 92(4)90 Pages: 1-7

    • DOI

      10.1095/biolreprod.114.125443

    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Efficacy of 2-Hydroxypropyl-β-cyclodextrin in Niemann–Pick Disease Type C Model Mice and Its Pharmacokinetic Analysis in a Patient with the Disease2015

    • Author(s)
      Tanaka Y, Yamada Y, Ishitsuka Y, Matsuo M, Shiraishi K, Wada K, Uchio Y, Kondo Y, Takeo T, Nakagata N, Higashi T, Motoyama K, Arima H, Mochinaga S, Higaki K, Ohno K, Irie T
    • Journal Title

      Biol. Pharm. Bull.

      Volume: 38 Issue: 6 Pages: 844-51

    • DOI

      10.1248/bpb.b14-00726

    • NAID

      130005072664

    • ISSN
      0918-6158, 1347-5215
    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Superovulation Using the Combined Administration of Inhibin Antiserum and Equine Chorionic Gonadotropin Increases the Number of Ovulated Oocytes in C57BL/6 Female Mice2015

    • Author(s)
      Toru Takeo and Naomi Nakagata
    • Journal Title

      PLoS One

      Volume: 10 Pages: 1-11

    • DOI

      10.1371/journal.pone.0128330

    • Related Report
      2015 Annual Research Report
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  • [Journal Article] HPGCD outperforms HPBCD as a potential treatment for Niemann-Pick disease type C during disease modeling with iPS cells2015

    • Author(s)
      Soga M, Ishitsuka Y, Hamasaki M, Yoneda K, Furuya H, Matsuo M, Ihn H, Fusaki N, Nakamura K, Nakagata N, Endo F, Irie T, Era T
    • Journal Title

      Stem Cells

      Volume: 33 Pages: 1075-1088

    • DOI

      10.1002/stem.1917

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Production of knockout mice by DNA microinjection of various CRISPR/Cas9 vectors into freeze-thawed fertilized oocytes2015

    • Author(s)
      Nakagawa Y, Sakuma T, Sakamoto T, Ohmuraya M, Nakagata N, Yamamoto T
    • Journal Title

      BMC Biotechnology

      Volume: - Pages: 33-33

    • DOI

      10.1186/s12896-015-0144-x

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Region-specific regulation of cell proliferation by Fgf receptor signaling during the Wolffian duct development2015

    • Author(s)
      Mika Okazawa, Aki Murashima, Masayo Harada, Naomi Nakagata, Masafumi Noguchi, Mitsuru Morimoto, Tadashi Kimura, David M. Ornitz, Gen Yamada
    • Journal Title

      Dev Biol.

      Volume: 1;400(1) Pages: 139-147

    • DOI

      10.1016/j.ydbio.2015.01.023

    • Related Report
      2015 Annual Research Report
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  • [Journal Article] Effects of cyclodextrins on GM1-gangliosides in fibroblasts from GM1-gangliosidosis patients.2015

    • Author(s)
      Maeda Y, Motoyama K, Higashi T, Horikoshi Y, Takeo T, Nakagata N, Kurauchi Y, Katsuki H, Ishitsuka Y, Kondo Y, Irie T, Furuya H, Era T, Arima H.
    • Journal Title

      Journal of Pharmacy and Pharmacology

      Volume: 67 Pages: 1133-1142

    • DOI

      10.1111/jphp.12405

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Tissue-specific roles of FGF signaling in external genitalia development2015

    • Author(s)
      Harada M, Omori A, Nakahara C, Nakagata N, Akita K, Yamada G.
    • Journal Title

      Dev Dyn

      Volume: - Pages: 759-773

    • DOI

      10.1002/dvdy.24277

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] 研究者と技術者が支える実験動物科学の柱を再考する:遺伝育種の立場から2015

    • Author(s)
      加藤秀樹
    • Journal Title

      実験動物技術

      Volume: 50 Pages: 57-66

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Asbestos and multi-walled carbon nanotubes generate distinct oxidative responses in inflammatory cells2015

    • Author(s)
      Funahashi F, Okazaki Y, Ito D, Asakawa A, Nagai H, Tajima M and Toyokuni S.
    • Journal Title

      J. Clin. Biochem. Nutr.

      Volume: 56 Issue: 2 Pages: 11-117

    • DOI

      10.3164/jcbn.14-92

    • NAID

      130004704983

    • ISSN
      0912-0009, 1880-5086
    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Minimal inflammogenicity of pristine single-wall carbon nanotubes.2015

    • Author(s)
      Toyokuni S, Jiang L, Kitaura R and Shinohara S.
    • Journal Title

      Nagoya J Med Sci

      Volume: 77 Pages: 195-202

    • NAID

      120005549565

    • Related Report
      2015 Annual Research Report
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  • [Journal Article] Receptor role of annexin A2 in the mesothelial endocytosis of crocidolite fibers.2015

    • Author(s)
      Yamashita K, Nagai H and Toyokuni S.
    • Journal Title

      Lab Invest

      Volume: 95 Pages: 749-764

    • DOI

      10.1038/labinvest.2015.28

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      2015 Annual Research Report
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  • [Journal Article] Malignant mesothelioma as an oxidative stress-induced cancer: An update.2015

    • Author(s)
      Chew SH and Toyokuni S.
    • Journal Title

      Free Radic Biol Med

      Volume: 86 Pages: 166-178

    • DOI

      10.1016/j.freeradbiomed.2015.05.002

    • Related Report
      2015 Annual Research Report
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  • [Journal Article] A trial to find appropriate animal models of dichloropropane-induced cholangiocarcinoma based on the hepatic distribution of glutathione S-transferases2015

    • Author(s)
      Zhang L, Zong C, Ichihara S, Naito H, Toyokuni S, Kumagai S, Ichihara G.
    • Journal Title

      J Occup Health

      Volume: 57 Issue: 6 Pages: 548-554

    • DOI

      10.1539/joh.15-0085-oa

      10.1539/joh.15-0085-OA

    • NAID

      130005116261

    • ISSN
      1341-9145, 1348-9585
    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Paraneoplastic Ma Antigen-Like 1 as a Potential Prognostic Biomarker in Human Pancreatic Ductal Adenocarcinoma2015

    • Author(s)
      Kuwae Y, Kakehashi A, Wakasa K, Wei M, Yamano S, Ishii N, Ohsawa M, Wanibuchi H
    • Journal Title

      Pancreas

      Volume: 44 Pages: 106-115

    • DOI

      10.1097/mpa.0000000000000220

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Determination of Hepatotoxicity and Its Underlying Metabolic Basis of 1,2-dichloropropane in Male Syrian Hamsters and B6C3F1 Mice.2015

    • Author(s)
      Gi M, Fujioka M, Yamano S, Shimomura E, Ishii N, Kakehashi A, Takeshita M, Wanibuchi H.
    • Journal Title

      Toxicol Sci

      Volume: 印刷中 Pages: 196-208

    • DOI

      10.1093/toxsci/kfv045

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Modifying effects of 1,2-dichloropropane on N-nitrosobis(2-oxopropyl)amine-induced cholangiocarcinogenesis in male Syrian hamsters2015

    • Author(s)
      Gi M, Fujioka M, Yamano S, Shimomura E, Kanki M, Kawachi S, Tachibana H, Tatsumi K, Fang H, Ishii N, Kakehashi A, Wanibuchi H.
    • Journal Title

      J. Toxicol. Sci.

      Volume: 40 Issue: 5 Pages: 647-656

    • DOI

      10.2131/jts.40.647

    • NAID

      130005098383

    • ISSN
      0388-1350, 1880-3989
    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Chemokine (C-C motif) ligand 3 detection in the serum of persons exposed to asbestos: A patient-based study2015

    • Author(s)
      Xu, J., Alexander, D. B., Iigo, M., Hamano, H., Takahashi, S., Yokoyama, T., Kato, M., Usami, I., Tokuyama, T., Tsutsumi, M., Tamura, M., Oguri, T., Niimi, A., Hayashi, Y., Yokoyama, Y., Tonegawa, K., Fukamachi, K., Futakuchi, M.,et al.
    • Journal Title

      Cancer Sci

      Volume: 106 Pages: 2112-2118

    • DOI

      10.1111/cas.12687

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] In vivo 18F‐fluorodeoxyglucose‐positron emission tomography/computed tomography imaging of pancreatic tumors in a transgenic rat model carrying the human KRASG12V oncogene2015

    • Author(s)
      Shibata, K., Fukamachi, K., Tsuji, T., Saga, T., Futakuchi, M., Nagino, M., Tsuda, H., and Suzui, M.
    • Journal Title

      Oncology Letters

      Volume: 9 Pages: 2112-2118

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Murine Herc6 Plays a Critical Role in Protein ISGylation In Vivo and Has an ISGylation-Independent Function in Seminal Vesicles.2015

    • Author(s)
      Arimoto KI, Hishiki T, Kiyonari H, Abe T, Cheng C, Yan M, Fan JB, Futakuchi M, Tsuda H, Murakami Y, Suzuki H, Zhang DE, Shimotohno K
    • Journal Title

      J Interferon Cytokine Res

      Volume: 35 Pages: 351-358

    • DOI

      10.1089/jir.2014.0113

    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
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  • [Journal Article] Mutual reinforcement of inflammation and carcinogenesis by the Helicobacter pylori CagA oncoprotein2015

    • Author(s)
      Suzuki, N.
    • Journal Title

      Sci. Rep.

      Volume: 5 Pages: 10024-10024

    • DOI

      10.1038/srep10024

    • Related Report
      2015 Annual Research Report
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  • [Journal Article] Ablation of the p16INK4a tumour suppressor reverses ageing phenotypes of klotho mice2015

    • Author(s)
      Seidai Sato, Yuka Kawamata, Akiko Takahashi, Yoshinori Imai, Aki Hanyu, Atsushi Okuma, Masaki Takasugi, Kimi Yamakoshi, Hiroyuki Sorimachi, Hiroaki Kanda, Yuichi Ishikawa, Saburo Sone, Yasuhiko Nishioka, Naoko Ohtani and Eiji Hara
    • Journal Title

      nature communications

      Volume: 6 Pages: 1-10

    • DOI

      10.1038/ncomms8035

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Inhibition of β-catenin and STAT3 with curcumin analog suppresses gastric carcinogenesis in vivo : a novel candidate for gastric cancer treatment2015

    • Author(s)
      Uehara, Y., Inoue, M., Fukuda, K., Yamakoshi, H., Hosoi, Y., Kanda, H., Oshima, M., Iwabuchi, Y., Shibata, H.
    • Journal Title

      Gastric Cancer

      Volume: 18 Pages: 774-783

    • DOI

      10.1007/s10120-014-0434-3

    • Description
      in press
    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
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  • [Journal Article] Reducing DNA methylation suppresses colon carcinogenesis by inducing tumor cell differentiation. Carcinogenesis.2015

    • Author(s)
      Hatano Y, Semi K, Hashimoto K, Lee MS, Hirata A, Tomita H, Kuno T, Takamatsu M, Aoki K, Taketo MM, Kim YJ, Hara A, Yamada Y.
    • Journal Title

      Carcinogenesis.

      Volume: 36 Pages: 719-29

    • DOI

      10.1093/carcin/bgv060

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Induced pluripotent stem cell technology for dissecting the cancer epigenome.2015

    • Author(s)
      Semi K, Yamada Y.
    • Journal Title

      Cancer Sci.

      Volume: 106 Pages: 1251-1256

    • DOI

      10.1111/cas.12758

    • NAID

      120005767027

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] KLF4 N-terminal variance modulates induced reprogramming to pluripotency.2015

    • Author(s)
      Kim SI, Oceguera-Yanez F, Hirohata R, Linker S, Okita K, Yamada Y, Yamamoto T, Yamanaka S, Woltjen K.
    • Journal Title

      Stem Cell Reports

      Volume: 4 Pages: 727-43

    • DOI

      10.1016/j.stemcr.2015.02.004

    • NAID

      120005745632

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Cigarette smoke inhalation and risk of lung cancer: a case-control study in a large Japanese population.2015

    • Author(s)
      Fukumoto K, Ito H, Matsuo K, Tanaka H, Yokoi K, Tajima K, Takezaki T.
    • Journal Title

      Eur J Cancer Prev

      Volume: 24(3) Pages: 195-200

    • DOI

      10.1097/cej.0000000000000034

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Genetic variants of SLC17A1 are associated with cholesterol homeostasis and hyperhomocysteinaemia in Japanese men2015

    • Author(s)
      Koyama, T. Matsui, D. Kuriyama, N. Ozaki, E. Tanaka, K. Oze, I. Hamajima, N. Wakai, K. Okada, R. Arisawa, K. Mikami, H. Shimatani, K. Hirata, A. Takashima, N. Suzuki, S. Nagata, C. Kubo, M. Tanaka, H.
    • Journal Title

      Sci. Rep.

      Volume: 5 Pages: 15888-15888

    • DOI

      10.1038/srep15888

    • NAID

      120006875676

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Declining trends in prevalence of Helicobacter pylori infection by birth-year in a Japanese population2015

    • Author(s)
      Watanabe M, Ito H, Hosono S, Oze I, Ashida C, Tajima K, Katoh H, Matsuo K, Tanaka H
    • Journal Title

      Cancer Sci

      Volume: 106(12) Pages: 1738-43

    • DOI

      10.1111/cas.12821

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Association between brain-muscle-ARNT-like protein-2 (BMAL2) gene polymorphism and type 2 diabetes mellitus in obese Japanese individuals: A cross-sectional analysis of the Japan Multi-institutional Collaborative Cohort Study.2015

    • Author(s)
      Yamaguchi M, Uemura H, Arisawa K, Katsuura-Kamano S, Hamajima N, Hishida A, Suma S, Oze I, Nakamura K, Takashima N, Suzuki S, Ibusuki R, Mikami H, Ohnaka K, Kuriyama N, Kubo M, Tanaka H.
    • Journal Title

      Diabetes Res Clin Pract

      Volume: 110 Pages: 301-308

    • DOI

      10.1016/j.diabres.2015.10.009

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] <i>ATP-binding cassette transporter A1</i> (<i>ABCA1</i>) R219K (G1051A, rs2230806) polymorphism and serum high-density lipoprotein cholesterol levels in a large Japanese population: cross-sectional data from the Daiko Study2015

    • Author(s)
      Mokuno J, Hishida A, Morita E, Sasakabe T, Hattori Y, Suma S, Okada R, Kawai S, Naito M, Wakai K
    • Journal Title

      Endocr J

      Volume: 62 Issue: 6 Pages: 543-549

    • DOI

      10.1507/endocrj.ej14-0577

      10.1507/endocrj.EJ14-0577

    • NAID

      130005085775

    • ISSN
      0918-8959, 1348-4540
    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Effects of IL6 C-634G polymorphism on tooth loss and their interaction with smoking habits2015

    • Author(s)
      Suma S, Naito M, Wakai K, Sasakabe T, Hattori Y, Okada R, Kawai S, Hishida A ,Morita E, Nakagawa H, Tamura T, Hamajima N
    • Journal Title

      Oral Dis

      Volume: 21 Pages: 807-813

    • DOI

      10.1111/odi.12352

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] No association between Helicobacter pylori infection and diabetes mellitus among a general Japanese population: a cross-sectional study2015

    • Author(s)
      Tamura T, Morita E, Kawai S, Sasakabe T, Sugimoto Y, Fukuda N, Suma S, Nakagawa H, Okada R, Hishida A, Naito M, Hamajima N, Wakai K
    • Journal Title

      Springerplus

      Volume: 4 Pages: 602-602

    • DOI

      10.1186/s40064-015-1371-2

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] GGT1 intronic A>G polymorphism affects setum concentration of γ-glutamyl transpeptidase among Japanese healthy adults2015

    • Author(s)
      Kawai S, Naito M, Morita E, Okada R, Hishida A, Wakai K, Hamajima N
    • Journal Title

      Ningen Dock International

      Volume: 2 Pages: 65-69

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Polymorphisms in CYP19A1, HSD17B1 and HSD17B2 genes and serum sex hormone level among postmenopausal Japanese women. Japan Multi-Institutional Collaborative Cohort (J-MICC) Study Group.2015

    • Author(s)
      Hosono S, Ito H, Oze I, Higaki Y, Morita E, Takashima N, Suzuki S, Shimatani K, Mikami H, Ohnaka K, Ozaki E. Katsuura-Kamano S, Kubo M, Nagata C, Naito M, Hamajima N, Tanaka H.
    • Journal Title

      Maturitas.

      Volume: 62 Pages: 394-401

    • DOI

      10.1016/j.maturitas.2015.08.003

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Serologically determined gastric mucosal condition is a predictive factor for osteoporosis in Japanese men.2015

    • Author(s)
      Mizuno S, Matsui D, Watanabe I, Ozaki E, Kuriyama N, Watanabe Y
    • Journal Title

      Dig Dis Sci

      Volume: 60 Pages: 2063-2069

    • DOI

      10.1007/s10620-015-3576-1

    • Description
      Epub ahead of print
    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Relationship between Cnm-positive Streptococcus mutans and cerebral microbleeds in humans.2015

    • Author(s)
      Miyatani F, Kuriyama N, Watanabe I, Nomura R, Nakano K, Matsui D, Ozaki E, Koyama T, Nishigaki M, Yamamoto T, Mizuno T, Tamura A, Akazawa K, Takada A, Takeda K, Yamada K, Nakagawa M, Ihara M, Kanamura N, Friedland RP, Watanabe Y.
    • Journal Title

      Oral Disease

      Volume: 21 Pages: 886-893

    • DOI

      10.1111/odi.12360

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Factors Associated With Non-participation in a Face-to-Face Second Survey Conducted 5 Years After the Baseline Survey2015

    • Author(s)
      Hara M, Shimanoe C, Otsuka Y, Nishida Y, Nanri H, Horita M, Yasukata J, Miyoshi N, Yamada Y, Higaki Y, Tanaka K.
    • Journal Title

      Journal of Epidemiology

      Volume: 25 Issue: 2 Pages: 117-125

    • DOI

      10.2188/jea.je20140116

      10.2188/jea.JE20140116

    • NAID

      130004704585

    • ISSN
      0917-5040, 1349-9092
    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Dietary Patterns and Serum Gamma-Glutamyl Transferase in Japanese Men and Women2015

    • Author(s)
      Nanri H, Hara M, Nishida Y, Shimanoe C, Nakamura K, Higaki Y, Imaizumi T, Taguchi N, Sakamoto T, Horita M, Shinchi K, Kokaze A, Tanaka K.
    • Journal Title

      Journal of Epidemiology

      Volume: 25 Issue: 5 Pages: 378-386

    • DOI

      10.2188/jea.je20140158

      10.2188/jea.JE20140158

    • NAID

      130005067867

    • ISSN
      0917-5040, 1349-9092
    • Description
      in press
    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Perceived stress and coping strategies in relation to body mass index: cross-sectional study of 12,045 Japanese men and women.2015

    • Author(s)
      Shimanoe C, Hara M, Nishida Y, Nanri H, Otsuka Y, Nakamura K, Higaki Y, Imaizumi T, Taguchi N, Sakamoto T, Horita M, Shinchi K, Tanaka K.
    • Journal Title

      Plos One

      Volume: 12

    • DOI

      10.1371/journal.pone.0118105

    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Incidence, serum IgE and TARC/CCL17 levels of atopic dermatitis in association with other related allergic diseases: An update from the Ishigaki Island cohort.2015

    • Author(s)
      Takeuchi S, Esaki H, Furusyo N, Hayashida S, Yamamura K, Tsuji G, Takemura M, Hayashi J, Furue M:
    • Journal Title

      Acta Dermato Venereologica

      Volume: 95 Pages: 480-484

    • DOI

      10.2340/00015555-1989

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Non-invasive fibrosis assessment predicts sustained virological response to telaprevir with pegylated interferon and ribavirin for chronic hepatitis C.2015

    • Author(s)
      Ogawa E, Furusyo N, Shimizu M, Ihara T, Hayashi T, Harada Y, Toyoda K, Murata M, Hayashi J:
    • Journal Title

      Antiviral Therapy

      Volume: 20 Pages: 185-192

    • DOI

      10.3851/imp2805

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Predictors of kidney tubular dysfunction by adefovir for chronic hepatitis B2015

    • Author(s)
      Shimizu M, Furusyo N, Ikezaki H, Ogawa E, Hayashi T, Ihara T, Harada Y, Toyoda T, Murata M, Hayashi J:
    • Journal Title

      World Journal of Gastroenterology

      Volume: 21 Pages: 2116-2123

    • DOI

      10.3748/wjg.v21.i7.2116

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Bacterial Infection as an Adverse Effect of Telaprevir-based Triple Therapy for Chronic Hepatitis C Infection2015

    • Author(s)
      Kawano A, Ogawa E, Furusyo N, Nakamuta M, Kajiwara E, Dohmen K, Nomura H, Takahashi K, Satoh T, Azuma K, Tanabe Y, Shimoda S, Kotoh K, Hayashi J , The Kyushu University Liver Disease Study (KULDS) Group.
    • Journal Title

      Intern. Med.

      Volume: 54 Issue: 6 Pages: 567-572

    • DOI

      10.2169/internalmedicine.54.3457

    • NAID

      130004903089

    • ISSN
      0918-2918, 1349-7235
    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The kinetics of the hepatitis B surface antigen level after the initiation of antiretroviral therapy for hepatitis B virus and human immunodeficiency virus coinfected patients.2015

    • Author(s)
      Mitsumoto F, Murata M, Ura K, Takayama K, Hiramine S, Shimizu M, Toyoda K, Ogawa E, Furusyo N, Hayashi J:
    • Journal Title

      Journal of Infection and Chemotherapy

      Volume: 21 Pages: 264-271

    • DOI

      10.1016/j.jiac.2014.12.003

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Direct acting antiviral agent-based therapy effectively decreases the serum alpha fetoprotein level of chronic hepatitis C patients2015

    • Author(s)
      Takayama K, Furusyo N, Ogawa E, Ikezaki H, Shimizu M, Masayuki M, Hayashi J.
    • Journal Title

      World Journal of Gastroenterology

      Volume: 21 Pages: 4696-4706

    • DOI

      10.3748/wjg.v21.i15.4696

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Glycated Albumin as a diagnostic tool for diabetes in a general population.2015

    • Author(s)
      Ikezaki H, Furusyo N, Ihara T, Hayashi T, Ura K, Hiramine S, Mitsumoto F, Takayama K, Murata M, Kohzuma T, Ai M, Schaefer EJ, Hayashi J.
    • Journal Title

      Metabolism

      Volume: 64 Pages: 698-705

    • DOI

      10.1016/j.metabol.2015.03.003

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Comparative safety study on severe anemia by simeprevir- versus telaprevir-based triple therapy for chronic hepatitis C.2015

    • Author(s)
      Ogawa E, Furusyo N, Kajiwara E, Nomura H, Kawano A, Takahashi K, Dohmen K, Satoh T, Azuma K, Nakamuta M, Koyanagi T, Kotoh K, Shimoda S, Hayashi J, The Kyushu University Liver Disease Study (KULDS) Group.
    • Journal Title

      Journal of Gastroenterology and Hepatology

      Volume: 30 Pages: 1309-1316

    • DOI

      10.1111/jgh.12945

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effectiveness of triple therapy with simeprevir for chronic hepatitis C genotype 1b patients with prior telaprevir failure.2015

    • Author(s)
      Ogawa E, Furusyo N, Dohmen K, Kajiwara E, Kawano A, Nomura H, Takahashi K, Satoh T, Azuma K, Nakamuta M, Koyanagi T, Kotoh K, Shimoda S, Hayashi J; The Kyushu University Liver Disease Study (KULDS) Group.
    • Journal Title

      Journal of Viral Hepatitis

      Volume: 22 Pages: 992-1001

    • DOI

      10.1111/jvh.12427

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comparative effectiveness and safety study of triple therapy with simeprevir or telaprevir for non-cirrhotic patients with chronic hepatitis C virus genotype 1b infection.2015

    • Author(s)
      Ogawa E, Furusyo N, Dohmen K, Kajiwara E, Kawano A, Nomura H, Takahashi K, Satoh T, Azuma K, Nakamuta M, Koyanagi T, Kotoh K, Shimoda S, Hayashi J; The Kyushu University Liver Disease Study (KULDS) Group.
    • Journal Title

      Journal of Gastroenterology and Hepatology

      Volume: 30 Pages: 1759-1767

    • DOI

      10.1111/jgh.13016

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Efficacy of interferon-beta plus ribavirin combination treatment on the development of hepatocellular carcinoma by Japanese patients with chronic hepatitis C.2015

    • Author(s)
      Ikezaki H, Nomura H, Furusyo N, Ogawa E, Kajiwara E, Takahashi K, Kawano A, Maruyama T, Tanabe Y, Satoh T Nakamuta M, Kotoh K, Azuma K, Dohmen K, Shimoda S, Hayashi J; The Kyushu University Liver Disease Study (KULDS) Group.
    • Journal Title

      Hepatology Research

      Volume: 46

    • DOI

      10.1111/hepr.12555

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Importance of virological response in the early stage of telaprevir-based triple therapy2015

    • Author(s)
      Hiramine S, Furusyo N, Ogawa E, Nakamuta M, Kajiwara E, Nomura H, Dohmen K, Takahashi K, Satoh T, Azuma K, Kawano A, Koyanagi T, Kotoh K, Shimoda S, Hayashi J
    • Journal Title

      World Journal of Hepatology

      Volume: 7 Pages: 2688-2695

    • DOI

      10.4254/wjh.v7.i26.2688

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The association between objective tongue color and endoscopic findings: results from the Kyushu and Okinawa population study (KOPS).2015

    • Author(s)
      Kainuma M, Furusyo N, Urita Y, Nagata M, Ihara T, Oji T, Nakaguchi T, Namiki T, Hayashi J.
    • Journal Title

      BMC Complementary and Alternative Medicine

      Volume: 15 Pages: 372-372

    • DOI

      10.1186/s12906-015-0904-0

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Epigenome-wide association study suggests that SNPs in the promoter region of RETN influence plasma resistin level via effects on DNA methylation at neighbouring sites.2015

    • Author(s)
      M. Nakatochi, S. Ichihara, K. Yamamoto, K. Ohnaka, Y. Kato, S. Yokota, A. Hirashiki, K. Naruse, H, Asano, H. Izawa, T. Matsubara, and M. Yokota
    • Journal Title

      Diabetologia

      Volume: 58 Pages: 2781-2190

    • DOI

      10.1007/s00125-015-3763-9

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Inter- and intra-individual variations in seasonal and daily stabilities of the human gut microbiota in Japanese.2015

    • Author(s)
      Hisada T, Endoh K, Kuriki K.
    • Journal Title

      Arch Microbiol.

      Volume: 197 Pages: 919-34

    • DOI

      10.1007/s00203-015-1125-0

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Interactions between Psychological Stress and Drinking Status in Relation to Diet among Middle-Aged Men and Women: A Large-Scale Cross-Sectional Study in Japan2015

    • Author(s)
      Endoh K, Kuriki K, Kasezawa N, Tohyama K, Goda T.
    • Journal Title

      J Nutr Sci Vitaminol

      Volume: 61 Issue: 1 Pages: 64-72

    • DOI

      10.3177/jnsv.61.64

    • NAID

      130005071833

    • ISSN
      0301-4800, 1881-7742
    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association between Smoking Status and Food and Nutrient Consumption in Japanese: a Large-Scale Cross-Sectional Study.2015

    • Author(s)
      Endoh K, Kuriki K, Kasezawa N, Tohyama K, Goda T.
    • Journal Title

      Asian Pac J Cancer Prev.

      Volume: 16(15) Pages: 6527-34

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The A allele at rs13419896 of EPAS1 is associated with enhanced expression and poor prognosis for non-small cell lung cancer.2015

    • Author(s)
      Andika C. Putra, Hidetaka Eguchi, Kian Leong Lee, Yuko Yamane, Ewita Gustine, Takeshi Isobe, Masahiko Nishiyama, Keiko Hiyama, Lorenz Poellinger, Keiji Tanimoto*.
    • Journal Title

      PLoS One.

      Volume: 10 Pages: 0134496-0134496

    • DOI

      10.1371/journal.pone.0134496

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Association of hair dye use with circulating levels of sex hormones in premenopausal Japanese women.2015

    • Author(s)
      Nagata C, Wada K, Tsuji M, Hayashi M, Takeda N, Yasuda K.
    • Journal Title

      Eur J Public Health

      Volume: 25 Pages: 895-9

    • DOI

      10.1093/eurpub/ckv020

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Establishiment of Tsc2-deficient rat embryonic stem cells.2015

    • Author(s)
      Ito Y., Kawano H., Kanai F., Nakamura E., Tada N., Takai S., Horie S., Arai H., Kobayashi T. & Hino O.
    • Journal Title

      Int J Oncol

      Volume: 46 Pages: 1944-1952

    • DOI

      10.3892/ijo.2015.2913

    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Environmental carcinognensis-100th anniversary of creating cancer.2015

    • Author(s)
      Misa Imai, Okio Hino
    • Journal Title

      Cancer Science

      Volume: 106 Pages: 1483-1485

    • DOI

      10.1111/cas.12798

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Telomere G-tail Length is a Promising Biomarker Related to White Matter Lesions and Endothelial Dysfunction in Patients With Cardiovascular Risk: A Cross-sectional Study.2015

    • Author(s)
      Nezu T, Hosomi N, Takahashi T, Anno K, Aoki S, Shimamoto A, Maruyama H, Hayashi T, Matsumoto M, Tahara H.
    • Journal Title

      EBioMedicine

      Volume: 2(8) Pages: 958-65

    • DOI

      10.1016/j.ebiom.2015.05.025

    • NAID

      120006796554

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Mutations in the gene encoding the E2 conjugating enzyme UBE2T cause Fanconi anemia.2015

    • Author(s)
      Hira A, Yoshida K, Sato K, Okuno Y, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Shimamoto A, Tahara H, Ito E, Kojima S, Kurumizaka H, Ogawa S, Takata M, Yabe H, Yabe M.
    • Journal Title

      American Journal of Human Genetics

      Volume: 96(6) Pages: 1001-1007

    • DOI

      10.1016/j.ajhg.2015.04.022

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Werner Syndrome-specific induced pluripotent stem cells: recovery of telomere function by reprogramming.2015

    • Author(s)
      Shimamoto, A., Yokote, K. & Tahara, H.
    • Journal Title

      Front Genet.

      Volume: 6 Pages: 10-10

    • DOI

      10.3389/fgene.2015.00010

    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] A potential function for neuronal exosomes: sequestering intracerebral amyloid-beta peptide.2015

    • Author(s)
      Yuyama, K., Sun, H., Usuki, S., Sakai, S., Hanamatsu, H., Mioka, T., Kimura, N., Okada, M., Tahara, H., Furukawa, J., Fujitani, N., Shinohara, Y. & Igarashi, Y.
    • Journal Title

      FEBS Lett.

      Volume: 589 Pages: 84-8

    • DOI

      10.1016/j.febslet.2014.11.027

    • NAID

      120005537475

    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] EVpedia: a community web portal for extracellular vesicles research.2015

    • Author(s)
      Kim, D.K., Lee, J., Kim, S.R., Choi, D.S., Yoon, Y.J., Kim, J.H., Go, G., Nhung, D., Hong, K., Jang, S.C., Kim, S.H., Park, K.S., Kim, O.Y., Park, H.T., Seo, J.H., Aikawa, E., Baj-Krzyworzeka, M., van Balkom, B.W., Belting, M., Blanc, & Tahara, H.
    • Journal Title

      Bioinformatics.

      Volume: 31 (6) Pages: 933-9

    • DOI

      10.1093/bioinformatics/btu741

    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Geographic particularities in incidence and etiopathogenesis of sporadic gastric cancer.2015

    • Author(s)
      Kadar Z, Jung I, Orlowska J, Szentirmay Z, Sugimura H, Turdean S, Simona G.
    • Journal Title

      Pol J Pathol.

      Volume: 66(3) Pages: 254-259

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Clinicopathological and Survival Analysis of Japanese Patients with Resected Non-Small-Cell Lung Cancer Harboring NKX2-1, SETDB1, MET, HER2, SOX2, FGFR1, or PIK3CA Gene Amplification.2015

    • Author(s)
      Inoue Y, Matsuura S, Kurabe N, Kahyo T, Mori H, Kawase A, Karayama M, Inui N, Funai K, Shinmura K, Suda T, Sugimura H
    • Journal Title

      J Thorac Oncol.

      Volume: 10 Pages: 1590-1600

    • DOI

      10.1097/jto.0000000000000685

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] New Insights in Histogenetic Pathways of Gastric Cancer.2015

    • Author(s)
      Gurzu S, Sugimura H, Orlowska J, Szentirmay Z, Jung I.
    • Journal Title

      Medicine (Baltimore)

      Volume: 94

    • DOI

      10.1097/md.0000000000001810

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Single skip metastasis in sentinel lymph node: In an early gastric cancer.2015

    • Author(s)
      Bara T Jr, Gurzu S, Jung I, Kadar Z, Sugimura H, Bara T.
    • Journal Title

      World J Gastroenterol.

      Volume: 21 Pages: 9803-9807

    • DOI

      10.3748/wjg.v21.i33.9803

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Novel roles for LIX1L in promoting cancer cell proliferation through ROS1-mediated LIX1L phosphorylation.2015

    • Author(s)
      Nakamura S, Kahyo T, Tao H, Shibata K, Kurabe N, Yamada H, Shinmura K, Ohnishi K, Sugimura H.
    • Journal Title

      Scientific Reports

      Volume: 5 Pages: 13474-13474

    • DOI

      10.1038/srep13474

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Associations between the orexin (hypocretin) receptor 2 gene polymorphism Val308Ile and nicotine dependence in genome-wide and subsequent association studies.2015

    • Author(s)
      Nishizawa D et al.
    • Journal Title

      Molecular Brain

      Volume: 8 Pages: 50-50

    • DOI

      10.1186/s13041-015-0142-x

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Hereditary diffuse gastric cancer--An overview.2015

    • Author(s)
      Gurzu S, Jung I, Orlowska J, Sugimura H, Kadar Z, Turdean S, Bara T Jr.
    • Journal Title

      Pathol Res Pract.

      Volume: 211 Pages: 629-632

    • DOI

      10.1016/j.prp.2015.06.003

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Association between AKT1 gene polymorphism rs2498794 and smoking-related traits with reference to cancer susceptibility2015

    • Author(s)
      Nishizawa, D., Kasai, S., Hasegawa, J., Sato,N., Tanioka, F., Sugimura, H., Ikeda, K. and Dobashi, Y.
    • Journal Title

      Biomed Res Int.

      Volume: 2015.94. Pages: 316829-316829

    • DOI

      10.1155/2015/316829

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Validity of Tissue Microarray by Immunohistochemistry.2015

    • Author(s)
      Fujita H, Takayama T, Takaoka N, Tan C, Igarashi H, Sugimura H, Ozono S.
    • Journal Title

      Clin Lab.

      Volume: 61(5-6) Pages: 569-574

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] NEIL1 p.Gln282Stop variant is predominantly localized in the cytoplasm and exhibits reduced activity in suppressing mutations.2015

    • Author(s)
      Shinmura K, Kato H, Kawanishi Y, Goto M, Tao H, Inoue Y, Nakamura S, Sugimura H.
    • Journal Title

      Gene

      Volume: 571 Pages: 33-42

    • DOI

      10.1016/j.gene.2015.06.043

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] CYP2A6 genetic polymorphism is associated with decreased susceptibility to squamous cell lung cancer in Japanese smokers2015

    • Author(s)
      Hosono H, Kumondai M, Arai T, Sugimura H, Sasaki T, Hirasawa N, Hiratsuka M
    • Journal Title

      Drug Metabolism and Pharmacokinetics

      Volume: 30 Issue: 4 Pages: 263-268

    • DOI

      10.1016/j.dmpk.2015.04.002

    • NAID

      50014429961

    • ISSN
      1347-4367
    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] BSND and ATP6V1G3: Novel Immunohistochemical Markers for Chromophobe Renal Cell Carcinoma.2015

    • Author(s)
      Shinmura K, Igarashi H, Kato H, Koda K, Ogawa H, Takahashi S, Otsuki Y, Yoneda T, Kawanishi Y, Funai K, Takayama T, Ozono S, Sugimura H.
    • Journal Title

      Medicine(Baltimore)

      Volume: 94(24)

    • DOI

      10.1097/md.0000000000000989

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Maspin-related Orchestration of Aggressiveness of Gastric Cancer.2015

    • Author(s)
      Gurzu S, Kadar Z, Sugimura H, Orlowska J, Bara T, Bara T Jr, Szederjesi J, Jung I.
    • Journal Title

      Appl Immunohistochem Mol Morphol.

      Volume: ahead of print

    • DOI

      10.1097/pai.0000000000000189

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] SASS6 overexpression is associated with mitotic chromosomal abnormalities and a poor prognosis in patients with colorectal cancer.2015

    • Author(s)
      Shinmura K, Kato H, Kawanishi Y, Nagura K, Kamo T, Okubo Y, Inoue Y, Kurabe N, Du C, Iwaizumi M, Kurachi K, Nakamura T, Sugimura H.
    • Journal Title

      Oncol Rep.

      Volume: 34 Pages: 727-738

    • DOI

      10.3892/or.2015.4014

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Cytological Features of a Variant NUT Midline Carcinoma of the Lung Harboring the NSD3-NUT Fusion Gene: A Case Report and Literature Review.2015

    • Author(s)
      Kuroda S, Suzuki S, Kurita A, Muraki M, Aoshima Y, Tanioka F, Sugimura H.
    • Journal Title

      Case Rep Pathol

      Volume: 2015 Pages: 572951-572951

    • DOI

      10.1155/2015/572951

    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] CD44-SLC1A2 fusion transcripts in primary colorectal cancer.2015

    • Author(s)
      Shinmura K, Kato H, Igarashi H, Inoue Y, Nakamura S, Du C, Kurachi K, Nakamura T, Ogawa H, Tanahashi M, Niwa H, Sugimura H.
    • Journal Title

      Pathol Oncol Res.

      Volume: 21 Pages: 759-764

    • DOI

      10.1007/s12253-014-9887-2

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] NSD3-NUT-expressing midline carcinoma of the lung: first characterization of primary cancer tissue.2015

    • Author(s)
      Suzuki S, Kurabe N, Ohnishi I, Yasuda K, Aoshima Y, Naito M, Tanioka F, Sugimura H.
    • Journal Title

      Pathol Res Pract.

      Volume: 211 Pages: 404-408

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] The inner centromere-shugoshin network prevents chromosomal instability2015

    • Author(s)
      Tanno Y, Susumu H, Kawamura M, Sugimura H, Honda T, Watanabe Y.
    • Journal Title

      Science

      Volume: 349 Pages: 1237-1240

    • DOI

      10.1126/science.aaa2655

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Panitumumab for locally advanced head and neck squamouse-cell carcinoma2015

    • Author(s)
      Ishiki H, Iwase S, Shimada N, Chiba T, Imai K.
    • Journal Title

      Lancet Oncology

      Volume: 16(4) Issue: 4

    • DOI

      10.1016/s1470-2045(15)70101-4

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis2015

    • Author(s)
      Mitsuhashi K, Nosho K, Sukawa Y, Matsunaga Y, Ito M, Kurihara H, Kanno S, Igarashi H, Naito T, Adachi Y, Tachibana M, Tanuma T, Maguchi H, Shinohara T, Hasegawa T, Imamura M, Kimura Y, Hirata K, Maruyama R, Suzuki H, Imai K, Yamamoto H, Shinomura Y
    • Journal Title

      Oncotarget

    • Description
      【掲載確定】 in press
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Microsatellite instability : an update2015

    • Author(s)
      Yamamoto H, Imai K
    • Journal Title

      Archives of Toxicology

    • Description
      【掲載確定】 in press
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Screening of drugs to treat 8p11 myeloproliferative syndrome using patient-derived induced pluripotent stem cells with fusion gene CEP110-FGFR12015

    • Author(s)
      Yamamoto S, Otsu M, Matsuzaka E, Konishi C, Takagi H, Hanada S, Mochizuki S, Nakauchi H, Imai K, Tsuji K, Ebihara Y
    • Journal Title

      Plos One

    • Description
      【掲載確定】 in press
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinicopathological and molecular characteristics of serrated lesions in Japanese elderly patients2015

    • Author(s)
      Nosho K, Igarashi H, Ito M, Mitsuhashi K, Kurihara H, Kanno S, Yoshii S, Mikami M, Takahashi H, Kusumi T, Hosokawa M, Sukawa Y, Adachi Y, Hasegawa T, Okita K, Hirata K, Maruyama R, Suzuki H, Imai K, Yamamoto H, Shinomura Y
    • Journal Title

      Digestion

      Volume: 91(1) Issue: 1 Pages: 57-63

    • DOI

      10.1159/000368820

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Contextual niche signals towards colorectal tumor progression by mesenchymal stem cell in the mouse xenograft model2015

    • Author(s)
      Nakagaki S, Arimura Y, Nagaishi K, Isshiki H, Nasuno M, Watanabe S, Idogawa M, Yamashita K, Naishiro Y, Adachi Y, Suzuki H, Fujimiya M, Imai K, Shinomura Y
    • Journal Title

      J Gastroenterol

    • Description
      【掲載確定】 Epub ahead of print
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 抗体医薬2015

    • Author(s)
      安井寛, 今井浩三
    • Journal Title

      DDS研究30年

      Volume: PHARMA TECH JAPAN 臨時増刊号,31(2)

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 抗体治療 特集「DDSがもたらした新しい臨床の風景」2015

    • Author(s)
      佐々木茂, 篠村恭久, 今井浩三
    • Journal Title

      Drug Delivery System

      Volume: 30 Issue: 1

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Requirement of DLG1 for cardiovascular development and tissue elongation during cochlear, enteric, and skeletal development : possible role in convergent extension2015

    • Author(s)
      Iizuka-Kogo, A., Senda, T., Akiyama, T., Shimomura, A., Nomura, R., Hasegawa, Y., Yamamura, K., Kogo, H., Sawai, N. and Matsuzaki, T.
    • Journal Title

      Plos One

    • Description
      in press
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Iron and thiols as two major players in carcinogenesis : friends or foes?2015

    • Author(s)
      Toyokuni, S.
    • Journal Title

      Nagoya J Med Sci

      Volume: 5

    • DOI

      10.3389/fphar.2014.00200

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Vascular endothelial growth factor mRNA levels as a biomarker for short-term N-butyl-N-(4-hydroxybutyl) nitrosamine-induced rat bladder carcinogenesis bioassay2015

    • Author(s)
      Wakui S, Mutou T, Takahashi H, Ikegami M, Wanibuchi H, Fukushima S
    • Journal Title

      J Appl Toxicol

      Volume: 35 Issue: 2 Pages: 181-190

    • DOI

      10.1002/jat.3021

    • NAID

      130005468570

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Percutaneous Carbon Dioxide Treatment using a Gas Mist Generator Enhances the Collateral Blood Flow in the Ischemic Hindlimb2015

    • Author(s)
      Izumi, Y
    • Journal Title

      J Atheroscler Thromb

      Volume: 22 Issue: 1 Pages: 474-480

    • DOI

      10.5551/jat.23770

    • NAID

      130004677973

    • ISSN
      1340-3478, 1880-3873
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Paraneoplastic Ma Antigen-Like 1 as a Potential Prognostic Biomarker in Human Pancreatic Ductal Adenocarcinoma2015

    • Author(s)
      Kuwae, Y, Kakehashi, A, Wakasa, K, Wei, M, Yamano, S, Ishii, N, Ohsawa, M, Wanibuchi, H
    • Journal Title

      Pancreas

      Volume: 44

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Determination of Hepatotoxicity and Its Underlying Metabolic Basis of 1,2-dichloropropane in Male Syrian Hamsters and B6C3F1 Mice2015

    • Author(s)
      Wei, M, Fujioka, M, Yamano, S, Shimomura, E, Ishii, N, Kakehashi, A, Takeshita, M, Wanibuchi, H
    • Journal Title

      Toxicol. Sci

    • Description
      in press
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] NPT1/SLC17A1 is a renal urate exporter in humans and its common gain-of-function variant decreases the risk of renal underexcretion gout.2015

    • Author(s)
      Chiba T, Matsuo H, Kawamura Y, Nagamori S, Nishiyama T, Wei L, Nakayama A, Nakamura T, Sakiyama M, Takada T, Taketani Y, Suma S, Naito M, Oda T, Kumagai H, Moriyama Y, Ichida K, Shimizu T, Kanai Y, Shinomiya N.
    • Journal Title

      Arthritis & Rheumatology

      Volume: 67(1) Pages: 281-287

    • DOI

      10.1002/art.38884

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Common variant of ALPK1 is not associated with gout: a replication study.2015

    • Author(s)
      Chiba T, Matsuo H, et al.
    • Journal Title

      Human Cell

      Volume: 28 Pages: 1-4

    • DOI

      10.1007/s13577-014-0103-1

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] HLA-A SNPs and amino acid variants are associated with nasopharyngeal carcinoma in Malaysian Chinese2015

    • Author(s)
      Chin, Y.M., Mushiroda T., Takahashi A., Kubo M., Krishnan G., Yap L.F., Teo S.H., Lim P.V., Yap Y.Y., Pua K.C., Kamatani N., Nakamura Y., Sam C.K., Khoo A.S., Malaysian N.P.C.S.G. and Ng C.C.
    • Journal Title

      Int J Cancer

      Volume: 136

    • DOI

      10.1002/ijc.29035

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Syndecan-1 responsive microRNA-126 and 149 regulate cell proliferation in prostate cancer.2015

    • Author(s)
      Tomomi Fujii, Keiji Shimada, Yoshihiro Tatsumi, Kiyohide Fujimoto, Noboru Konishi
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 456 Pages: 183-189

    • DOI

      10.1016/j.bbrc.2014.11.056

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Fine-Scale Mapping of the 5q11.2 Breast Cancer Locus Reveals at Least Three Independent Risk Variants Regulating MAP3K12015

    • Author(s)
      Glubb, D.M., Maranian M.J., Michailidou K., Pooley K.A., Meyer K.B., Kar S., Carlebur S., O'Reilly M., Betts J.A., Hillman K.M., Kaufmann S., Beesley J., Hopper J.L., Southey M.C., Apicella C., Schmidt M.K., Matsuo K., Ito H., Iwata H., Tanaka H., et al.
    • Journal Title

      Am J Hum Genet

      Volume: 96

    • DOI

      10.1016/j.ajhg.2014.11.009

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Gastric cancer in young vs old Romanian patients: immunoprofile with emphasis on maspin and mena protein reactivity.2015

    • Author(s)
      Gurzu S, Kadar Z, Sugimura H, Bara T, Bara T Jr, Halmaciu I, Jung I.
    • Journal Title

      APMIS

      Volume: 123 Pages: 223-233

    • DOI

      10.1111/apm.12347

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A meta-analysis of genome-wide association studies for adiponectin level in East Asians identifies a novel locus near WDR11-FGFR2.2015

    • Author(s)
      M.Yokota(他49 名、47番目)et al
    • Journal Title

      Hum Mol Genet.

      Volume: 23(4) Pages: 1108-1119

    • DOI

      10.1093/hmg/ddu583

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese.2015

    • Author(s)
      Hirokawa M, Morita H, Tajima T, Takahashi A, Ashikawa K, Miya F, Shigemizu D, Ozaki K, Sakata Y, Nakatani D, Suna S, Imai Y, …, Kadowaki T, Nakamura Y, Nagai R, Komuro I, Kubo M
    • Journal Title

      Eur. J. Hum. Genet.

      Volume: 23 Pages: 374-380

    • DOI

      10.1038/ejhg.2014.110

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Low FOXA1 expression predicts good response to neo-adjuvant chemotherapy resulting in good outcomes for luminal HER2-negative breast cancer cases2015

    • Author(s)
      Horimoto, Y., Arakawa A., Harada-Shoji N., Sonoue H., Yoshida Y., Himuro T., Igari F., Tokuda E., Mamat O., Tanabe M., Hino O. and Saito M.
    • Journal Title

      Br J Cancer

      Volume: 112

    • DOI

      10.1038/bjc.2014.595

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians.2015

    • Author(s)
      Hwang JY, Sim X, Wu Y, Liang J, Tabara Y, Hu C, Hara K, Tam CH, Cai Q, Zhao Q, Jee S, …, Kadowaki T, Jia W, Miki T : Qi L, Tai ES, Mohlke KL, Han BG, Cho YS, Kim BJ
    • Journal Title

      Diabetes

      Volume: 64 Pages: 291-298

    • DOI

      10.2337/db14-0563

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Circulating Pigment Epithelium-derived Factor (PEDF) Is Associated with Pathological Grade of Prostate Cancer2015

    • Author(s)
      Ide, H., Yamagishi S., Lu Y., Sakamaki K., Nakajima A., Horiuchi A., Kitamura K., Hisasue S., Muto S., Yamaguchi R. and Horie S.
    • Journal Title

      Anticancer Res

      Volume: 35

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] B-RAF mutation and accumulated gene methylation in aberrant crypt foci (ACF), sessile serrated adenoma/polyp (SSA/P) and cancer in SSA/P2015

    • Author(s)
      Inoue A, Okamoto K, Fujino Y, Nakagawa T, Muguruma N, Sannomiya K, Mitsui Y, Takaoka T, Kitamura S, Miyamoto H, Okahisa T, Fujimori T, Imoto I, Takayama T
    • Journal Title

      Br J Cancer

      Volume: 112 Pages: 403-412

    • DOI

      10.1038/bjc.2014.545

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comparison of plasma levels of nutrient-related biomarkers among Japanese populations in Tokyo, Japan, Sao Paulo, Brazil, and Hawaii, USA2015

    • Author(s)
      Iwasaki, M., Franke A.A., Hamada G.S., Miyajima N.T., Sharma S., Ishihara J., Takachi R., Tsugane S. and Le Marchand L.
    • Journal Title

      Eur J Cancer Prev

      Volume: 24

    • DOI

      10.1097/cej.0000000000000136

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comparison of plasma levels of obesity-related biomarkers among Japanese populations in Tokyo, Japan, Sao Paulo, Brazil, and Hawaii, USA2015

    • Author(s)
      Iwasaki, M., Le Marchand L., Franke A.A., Hamada G.S., Miyajima N.T., Sharma S., Yamaji T. and Tsugane S.
    • Journal Title

      Eur J Cancer Prev

    • DOI

      10.1097/cej.0000000000000123

    • Description
      Epub ahead of print
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genome-wide association study identified SNP on 15q24 associated with bladder cancer risk in Japanese population.2015

    • Author(s)
      Matsuda K, Takahashi A, Middlebrooks CD, Obara W, Nasu Y, Inoue K, Tamura K, Yamasaki I, Naya Y, Tanikawa C, Cui R, Figueroa JD, Silverman DT, Rothman N, Namiki M, Tomita Y, Nishiyama H, Kohri K, Deguchi T, Nakagawa M, Yokoyama M, Miki T, Kumon H, Fujioka T, Prokunina-Olsson L, Kubo M, Nakamura Y, Shuin T.
    • Journal Title

      Hum Mol Genet

      Volume: 24 Pages: 1177-1184

    • DOI

      10.1093/hmg/ddu512

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Validity of the food frequency questionnaire in a population with high alcohol consumption in Japan2015

    • Author(s)
      Nakahata, T.N., Takada N.A., Imaeda N., Goto C., Kuwabara H.K., Niimura H., Arai H., Yoshita Y. and Takezaki T.K.
    • Journal Title

      Asia Pac J Clin Nutr

    • Description
      in press
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] CD44-expressing undifferentiated carcinoma with rhabdoid features of the pancreas: molecular analysis of aggressive invasion and metastasis.2015

    • Author(s)
      Ohtomo T, Yoshitani N, Nishitsuji K, Takayama T, Yagagisawa Y, Takeya M, Sakashita N
    • Journal Title

      Pathology international

      Volume: 65 Pages: 264-270

    • DOI

      10.1111/pin.12283

    • Description
      Epub ahead of print
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Peretinoin after curative therapy of hepatitis C-related hepatocellular carcinoma: a randomized double-blind placebo-controlled study.2015

    • Author(s)
      Okita K, Izumi N, Matsui O, Tanaka K, Kaneko S, Moriwaki H, Ikeda K, Osaki Y, Numata K, Nakachi K, Kokudo N, Imanaka K, Nishiguchi S, Okusaka T, Nishigaki Y, Shiomi S, Kudo M, Ido K, Karino Y, Hayashi N, Ohashi Y, Makuuchi M, Kumada H
    • Journal Title

      J Gastroenterol

      Volume: 50 Pages: 191-202

    • DOI

      10.1007/s00535-014-0956-9

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Cotyledonoid dissecting leiomyoma of the uterus : report of two cases2015

    • Author(s)
      Saeki, H., Suzuki C., Yamasaki S., Hashizume A., Izumi H., Suzuki F., Ishi K., Nojima M. and Hino O.
    • Journal Title

      Arch Gynecol Obstet

      Volume: 291

    • DOI

      10.1007/s00404-014-3406-2

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association between endometriosis and the interleukin 1A (IL1A) locus2015

    • Author(s)
      Sapkota, Y., Low S.K., Attia J., Gordon S.D., Henders A.K., Holliday E.G., MacGregor S., Martin N.G., McEvoy M., Morris A.P., Takahashi A., Scott R.J., Kubo M., Zondervan K.T., Montgomery G.W. and Nyholt D.R.
    • Journal Title

      Hum Reprod

      Volume: 30

    • DOI

      10.1093/humrep/deu267

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The oncological outcome and validation of Japan Cancer of the Prostate Risk Assessment score among men treated with primary androgen-deprivation therapy2015

    • Author(s)
      Shiota, M., Yokomizo A., Takeuchi A., Imada K., Kiyoshima K., Inokuchi J., Tatsugami K. and Naito S.
    • Journal Title

      J Cancer Res Clin Oncol

      Volume: 141

    • DOI

      10.1007/s00432-014-1828-7

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Integrated analysis of whole genome and transcriptome sequencing reveals diverse transcriptomic aberrations driven by somatic genomic changes in liver cancers2015

    • Author(s)
      Shiraishi Y, Fujimoto A, Furuta M, Chayama K, Tsunoda T, Miyano S, and Nakagawa H, 他
    • Journal Title

      PLoS One.

      Volume: 9

    • DOI

      10.1371/journal.pone.0114263

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Associations between polymorphisms of interleukin-6 and related cytokine genes and serum liver damage markers: a cross-sectional study in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study.2015

    • Author(s)
      Sugimoto Y, Wakai K, Nakagawa H, Suma S, Sasakabe T, Sakamoto T, Takashima N, Suzuki S, Ogawa S, Ohnaka K, Kuriyama N, Arisawa K, Mikami H, Kubo M, Hosono S, Hamajima N, Tanaka H; J-MICC Study Group.
    • Journal Title

      Gene

      Volume: 557 Pages: 158-162

    • DOI

      10.1016/j.gene.2014.12.025

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rheb activation disrupts spine synapse formation through accumulation of syntenin in tuberous sclerosis complex2015

    • Author(s)
      Hiroko Sugiura, Shin Yasuda, Shutaro Katsurabayashi, Hiroyuki Kawano, Kentaro Endo, Kotaro Takasaki, Katsunori Iwasaki, Masumi Ichikawa, Toshiyuki Kobayashi, Okio Hino and Kanato Yamagata
    • Journal Title

      Nature Commun.

      Volume: 6 Pages: 6842-6842

    • DOI

      10.1038/ncomms7842

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] NSD3-NUT-expressing midline carcinoma of the lung: First characterization of primary cancer tissue.2015

    • Author(s)
      Suzuki S, Kurabe N, Ohnishi I, Yasuda K, Aoshima Y, Naito M, Tanioka F, Sugimura H.
    • Journal Title

      Pathol Res Pract

      Volume: 211 Pages: 404-408

    • DOI

      10.1016/j.prp.2014.10.013

    • Description
      Epub ahead of print
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Urethral toxicity after LDR brachytherapy : experience in Japan2015

    • Author(s)
      Tanaka, N., Asakawa I., Hasegawa M. and Fujimoto K.
    • Journal Title

      Brachytherapy

      Volume: 14

    • DOI

      10.1016/j.brachy.2014.09.009

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinical outcomes of a novel therapeutic vaccine with Tax peptide-pulsed dendritic cells for adult T-cell leukemia/lymphoma in a pilot study.2015

    • Author(s)
      Suehiro Y, Atsuhiko Hasegawa A, Tadafumi Iino T, Amane Sasada A, Nobukazu Watanabe N, Masao Matsuoka M, Ayako Takamori A, Ryuji Tanosaki R, Atae Utsunomiya A, Ilseung Choi I, Tetsuya Fukuda T, Osamu Miura O, Shigeo Takaishi S, Takanori Teshima T, Koichi Akashi K, Mari Kannagi M, Naokuni Uike N, Jun Okamura J
    • Journal Title

      British journal of haematology

      Volume: 169 Pages: 356-367

    • DOI

      10.1111/bjh.13302

    • Description
      印刷中
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Involvement of double-stranded RNA-dependent protein kinase and antisense viral RNA in the constitutive NFκB activation in adult T-cell leukemia/lymphoma cells.2015

    • Author(s)
      Kinpara S, Ito S, Takahata T, Saitoh Y, Hasegawa A, Kijiyama M, Utsunomiya A, Masuda M, Miyazaki Y, Matsuoka M, Nakamura M, Yamaoka S, Masuda T, Kannagi M.
    • Journal Title

      Leukemia

      Volume: 1 Pages: 1-5

    • DOI

      10.1038/leu.2015.1

    • Description
      印刷中
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Fatal reactivation of hepatitis B virus infection in a patient with adult T-cell leukemia-lymphoma receiving the anti-CC chemokine receptor 4 antibody mogamulizumab.2015

    • Author(s)
      Ifuku H, Kusumoto S, Tanaka Y, Totani H, Ishida T, Okada M, Murakami S, Mizokami M, Ueda R, Iida S.
    • Journal Title

      Hepatology research : the official journal of the Japan Society of Hepatology

      Volume: in press

    • DOI

      10.1111/hepr.12513

    • Description
      印刷中
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Dose-intensified chemotherapy alone or in combination with mogamulizumab in newly diagnosed aggressive adult T-cell leukaemia-lymphoma: a randomized phase II study.2015

    • Author(s)
      Ishida T, Jo T, Takemoto S, Suzushima H, Uozumi K, Yamamoto K, Uike N, Saburi Y, Nosaka K, Utsunomiya A, Tobinai K, Fujiwara H, Ishitsuka K, Yoshida S, Taira N, Moriuchi Y, Imada K, Miyamoto T, Akinaga S, Tomonaga M, Ueda R
    • Journal Title

      Br J Haematol.

      Volume: 未定 Pages: 672-682

    • DOI

      10.1111/bjh.13338

    • Description
      印刷中
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prognostic significance of tryptophan catabolism in adult T-cell leukemia/lymphoma2015

    • Author(s)
      Masaki, A., Ishida, T., Maeda, Y., Suzuki, S., Ito, A., Takino, H., Ogura, H., Totani, H., Yoshida, T., Kinoshita, S., Narita, T., Ri, M., Kusumoto, S., Inagaki, A., Komatsu, H., Niimi, A., Ueda, R., Utsunomiya, A., Inagaki, H. & Iida, S.
    • Journal Title

      Clin Cancer Res.

      Volume: 21 (12) Pages: 2830-2839

    • DOI

      10.1158/1078-0432.ccr-14-2275

    • NAID

      130005130183

    • Description
      印刷中
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] CD30-positive primary bone marrow lymphoma mimicking Hodgkin lymphoma2015

    • Author(s)
      Suzuki T, Kusumoto S, Masaki A, Ishida T, Inagaki H, Iida S, Mori F.
    • Journal Title

      Int J Hematol

      Volume: 印刷中 Issue: 2 Pages: 109-11

    • DOI

      10.1007/s12185-014-1714-8

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reactivation of hepatitis B virus (HBV) infection in adult T-cell leukemia-lymphoma patients with resolved HBV infection following systemic chemotherapy2015

    • Author(s)
      Totani H, Kusumoto S, Ishida T, Masuda A, Yoshida T, Ito A, Ri M, Komatsu H, Murakami S, Mizokami M, Ueda R, Niimi A, Inagaki H, Tanaka Y, Iida S.
    • Journal Title

      International journal of hematology

      Volume: 印刷中 Pages: 398-404

    • DOI

      10.1007/s12185-015-1750-z

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] TCF1 and LEF1 act as T-cell intrinsic HTLV-1 antagonists by targeting Tax.2015

    • Author(s)
      Ma G, Yasunaga J-I, Akari H, and Matsuoka M
    • Journal Title

      Proc. Natl. Acad. Sci. USA,

      Volume: 112 Pages: 2216-2221

    • DOI

      10.1073/pnas.1419198112

    • NAID

      120005537695

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Human T-cell leukemia virus type 1 Tax oncoprotein represses the expression of the BCL11B tumor suppressor in T-cells2015

    • Author(s)
      Takachi T, Takahashi M, Takahashi-Yoshita M, Higuchi M, Obata M, Mishima Y, Okuda S, Tanaka Y, Matsuoka M, Saitoh A, Green PL, Fujii M.
    • Journal Title

      Cancer Science

      Volume: 106(4) Pages: 461-465

    • DOI

      10.1111/cas.12618

    • NAID

      120006844098

    • Description
      in press
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Re-evaluation of screening of plasma positive for human T-cell leukemia virus type 1 using a luciferase immunoprecipitation system in blood donors.2015

    • Author(s)
      Furuta RA, Ma G, Matsuoka M, Otani S, Matsukura H, Hirayama F.
    • Journal Title

      Transfusion

      Volume: 55 Pages: 880-889

    • DOI

      10.1111/trf.12911

    • Description
      in press
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Visualization of HTLV-1-specific cytotoxic T lymphocytes in the spinal cords of patients with HTLV-1-associated myelopathy/tropical spastic paraparesis.2015

    • Author(s)
      Matsuura E, Kubota R, Tanaka Y, Takashima H, Izumo S
    • Journal Title

      J Neuropathol Exp Neurol

      Volume: 74 Issue: 1 Pages: 2-14

    • DOI

      10.1097/nen.0000000000000141

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Separate cellular localizations of human T-lymphotropic virus 1 (HTLV-1) Env and glucose transporter type 1 (GLUT1) are required for HTLV-1 Env-mediated fusion and infection2015

    • Author(s)
      Maeda Y, Terasawa H, Tanaka Y, Mitsuura C, Nakashima K, Yusa K, Harada S
    • Journal Title

      J Virol

      Volume: 89 Issue: 1

    • DOI

      10.1128/jvi.02686-14

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mogamulizumab, an anti-CCR4 antibody, targets human T-lymphotropic virus type 1-infected CD8+ and CD4+ T cells to treat associated myelopathy.2015

    • Author(s)
      Yamauchi J, Coler-Reilly A, Sato T, Araya N, Yagishita N, Ando H, Kunitomo Y, Takahashi K, Tanaka Y, Shibagaki Y, Nishioka K, Nakajima T, Hasegawa Y, Utsunomiya A, Kimura K, Yamano Y.
    • Journal Title

      J Infect Dis

      Volume: 211 Issue: 2 Pages: 238-248

    • DOI

      10.1093/infdis/jiu438

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Advanced HTLV-1 carriers and early-stage indolent ATLs are indistinguishable based on CADM1 positivity in flow cytometry2015

    • Author(s)
      Kobayashi S, Watanabe E, Ishigaki T, Ohno N, Yuji K, Nakano K, Yamochi T, Watanabe N, Tojo A, Watanabe T, Uchimaru K.
    • Journal Title

      Cancer Science

      Volume: 印刷中 Pages: 598-603

    • DOI

      10.1111/cas.12639

    • Description
      Epub ahead of print
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Identification of TL-Om1, an ATL Cell Line, as a Reference Material for Human T-Lymphotropic Virus 1 Quantitative PCR.2015

    • Author(s)
      Kuramitsu M, Okuma K, Yamagishi M, Yamochi T, Firouzi S, Momose H, Mizukami T, Takizawa K, Araki K, Sugamura K, Yamaguchi K, Watanabe T, Hamaguchi I.
    • Journal Title

      Journal of clinical microbiology

      Volume: 53 Issue: 2 Pages: 587-596

    • DOI

      10.1128/jcm.02254-14

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Epigenetic Heterogeneity in HIV-1 Latency Establishment2015

    • Author(s)
      Matsuda Y, Kobayashi-Ishihara M, Fujikawa D, Ishida T, Watanabe T, Yamagishi M
    • Journal Title

      Sci Rep

      Volume: 5

    • DOI

      10.1038/srep07701

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cancer-associated fibroblast-targeted strategy enhances antitumor immune responses in dendritic cell-based vaccine.2015

    • Author(s)
      Ohshio Y, Teramoto K, Hanaoka J, Tezuka N, Itoh Y, Asai T, Daigo Y, Ogasawara K
    • Journal Title

      Cancer Sci

      Volume: 106 Pages: 134-142

    • DOI

      10.1111/cas.12584

    • Description
      [Epub ahead of print]
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] SMK-17, a MEK1/2-specific inhibitor, selectively induces apoptosis in β-catenin-mutated tumors.2015

    • Author(s)
      Kiga M, Nakayama A, Shikata Y, Sasazawa Y, Murakami R, Nakanishi T, Tashiro E, Imoto M.
    • Journal Title

      Sci. Rep.

      Volume: 5 Pages: 8155-8155

    • DOI

      10.1038/srep08155

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Basal expression of insulin-like growth factor l receptor determines intrinsic resistance of cancer cells to a phosphatidylinositol 3-kinase inhibitor ZSTK4742015

    • Author(s)
      Isoyama S, Kajiwara G, Tamaki N, Okamura M, Yoshimi H, Nakamura N, Kawamura K, Nishimura Y, Namatame N, Yamori T, Dan S
    • Journal Title

      Cancer Sci

      Volume: 106 Issue: 2

    • DOI

      10.1111/cas.12582

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Design, synthesis and structure-activity relationships of 1-ethylpyrazole-3-carboxamide as novel HIF-1 inhibitors2015

    • Author(s)
      Yasuda Y, Arakawa T, Nawata Y, Shimada S, Oishi S, Fujii N, Nishimura S, Hattori A, Kakeya H
    • Journal Title

      Bioorg. Med. Chem.

      Volume: 23

    • DOI

      10.1016/j.bmc.2015.02.038

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mesenchymal stem cells cancel azoxymethane-induced tumor initiation2014

    • Author(s)
      Nasuno M, Arimura Y, Nagaishi K, Isshiki H, Onodera K, Nakagaki S, Watanabe S, Idogawa M, Yamashita K, Naishiro Y, Adachi Y, Suzuki H, Fujimiya M, Imai K, Shinomura Y
    • Journal Title

      STEM CELLS

      Volume: 32 Issue: 4 Pages: 913-25

    • DOI

      10.1002/stem.1594

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] MicroRNA-31 expression in relation to BRAF mutation, CpG island methylation and colorectal continuum in serrated lesions2014

    • Author(s)
      Ito M, Mitsuhashi K, Igarashi H, Nosho K, Yamamoto H
    • Journal Title

      International Journal of Cancer

      Volume: (Epub ahead of print) Issue: 11 Pages: 2507-15

    • DOI

      10.1002/ijc.28920

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The effect of IGF-I receptor blockade for human esophageal squamous cell carcinoma and adenocarcinoma2014

    • Author(s)
      Adachi Y, Ohashi H, Imsumran A, Yamamoto H, Matsunaga Y, Taniguchi H, Nosho K, Suzuki H, Sasaki Y, Arimura Y, Carbone DP, Imai K, Shinomura Y
    • Journal Title

      Tumor Biol

      Volume: 35 Issue: 2 Pages: 973-85

    • DOI

      10.1007/s13277-013-1131-2

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Analysis of DNA methylation in bowel lavage fluid for detection of colorectal cancer.2014

    • Author(s)
      Harada T, Yamamoto E, Yamano HO, Nojima M, Maruyama R, Kumegawa K, Ashida M, Yoshikawa K, Kimura T, Harada E, Takagi R, Tanaka Y, Aoki H, Nishizono M, Nakaoka M, Tuyada A, Niinuma T, Kai M, Shimoda K, Shinomura Y, Sugai T, Imai K, Suzuki H.
    • Journal Title

      Cancer Prevention Research (Philadelphia, Pa.)

      Volume: 7(10) Issue: 10 Pages: 1002-10

    • DOI

      10.1158/1940-6207.capr-14-0162

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Overview and Future prospect of “Promotion plan for the platform of human resource development for cancer”2014

    • Author(s)
      Imai K.
    • Journal Title

      Juntendo Medical Journal

      Volume: 60 Issue: 3

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] IGF2 differentially methylated region hypomethylation in relation to pathological and molecular features of serrated lesions2014

    • Author(s)
      Naito T, Nosho K, Ito M, Igarashi H, Mitsuhashi K, Yoshii S, Aoki H, Nomura M, Sukawa Y, Yamamoto E, Adachi Y, Takahashi H, Hosokawa M, Fujita M, Takenouchi T, Maruyama R, Suzuki H, Baba Y, Imai K, Yamamoto H, Ogino S, Shinomura Y.
    • Journal Title

      World J Gastroenterol

      Volume: 20(29) Issue: 29 Pages: 10050-61

    • DOI

      10.3748/wjg.v20.i29.10050

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] DNA synthesis inhibitors for the treatment of gastrointestinal cancer2014

    • Author(s)
      Yasui H, Tsurita G, Imai K
    • Journal Title

      Expert Opin Pharmacother

      Volume: 15 Issue: 16 Pages: 2361-2372

    • DOI

      10.1517/14656566.2014.958074

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The Use of Bone Marrow Stromal Cells (Bone Marrow-Derived Multipotent Mesenchymal Stromal Cells) for Alveolar Bone Tissue Engineering: Basic Science to Clinical Translation2014

    • Author(s)
      Kagami H, Agata H, Inoue M, Asahina I, Tojo A, Yamashita N, Imai K.
    • Journal Title

      Tissue Engineering Part B : Reviews

      Volume: 20(3) Issue: 3 Pages: 229-232

    • DOI

      10.1089/ten.teb.2013.0578

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association of microRNA-31-5p with clinical efficacy of anti-EGFR therapy in patients with metastatic colorectal cancer2014

    • Author(s)
      Igarashi H, Kurihara H, Mitsuhashi K, Ito M, Okuda H, Kanno S, Naito T, Yoshii S, Takahashi H, Kusumi T, Hasegawa T, Sukawa Y, Adachi Y, Okita K, Hirata K, Imamura Y, Baba Y, Imai K, Suzuki H, Yamamoto H, Nosho K, Shinomura Y
    • Journal Title

      Annals of Surgical Oncology

    • Description
      Epub ahead of print
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 総説 橋渡し研究の展開と我が国の医療2014

    • Author(s)
      今井浩三
    • Journal Title

      東京都病院薬剤師会雑誌

      Volume: 63 Issue: 2

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 人口動態に基づいた日本医療の未来予測-高齢多死社会の到来, 特集「超高齢者に対する外科治療の問題点」2014

    • Author(s)
      湯地晃一郎, 井元清哉, 山口類, 宮野悟, 上昌広, 今井浩三
    • Journal Title

      南江堂臨床雑誌「外科」

      Volume: 76 Issue: 5

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 大規模コホートを用いた大腸癌のノンコーディングRNA発現異常と生活習慣の分子疫学的解析2014

    • Author(s)
      能正勝彦, 五十嵐央祥, 伊藤美樹, 三橋慧, 栗原弘義, 菅野伸一, 内藤崇史, 須河安恭敬, 松永康孝, 足立靖, 野島正寛, 今井浩三, 丸山玲緒, 鈴木拓, 山本博幸, 篠村恭久
    • Journal Title

      日本癌病態治療研究会誌

      Volume: 20 Issue: 1

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] がんエピゲノム異常を理解し、応用し、そして制御するために2014

    • Author(s)
      鈴木拓, 今井浩三
    • Journal Title

      実験医学

      Volume: 32 Issue: 19

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Generation and analysis of serine protease inhibitor Kazal type 3-cre driver mice2014

    • Author(s)
      Sakata, K., Ohmuraya, M., Araki, K., Suzuki, C., Ida, S., Hashimoto, D., Wang, J., Uchiyama, Y., Baba, H. and Yamamura, K.
    • Journal Title

      Exp. Anim.

      Volume: 63

    • NAID

      130003391605

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Autophagy regulation in the pancreatic acinar cells is independent of epidermal growth factor receptor signaling.2014

    • Author(s)
      Ozaki, N., Fukuchi, Y., Tomiyoshi, S., Uehara1, H., Ida, S., Wang, J., Kimi Araki, K., Sibilia, M., Baba, H., and Yamamura, K. and Ohmuraya, M.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 446 Pages: 2-2

    • DOI

      10.1016/j.bbrc.2014.02.111

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Low serum level of high-sensitivity C-reactive protein in a Japanese subject with MODY3.2014

    • Author(s)
      Ohki T, Utsu Y, Morita S, Karim MF, Sato Y, Yoshizawa T, Yamamura K, Yamada K, Kasayama S, Yamagata K.
    • Journal Title

      J. Diabetes Invest

      Volume: in press Pages: 513-516

    • DOI

      10.1111/jdi.12237

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genetic analysis of the role of Alx4 in the coordination of lower body and external genitalia formation,2014

    • Author(s)
      Daisuke Matsumaru, Ryuma Haraguchi, Anne M. Moon, Yoshihiko Satoh, Naomi Nakagata, Ken-ichi Yamamur, Naoki Takahashi, Sohei Kitazawa, Gen Yamada.
    • Journal Title

      Eur. J. Human Genet

      Volume: 22(3) Pages: 350-357

    • DOI

      10.1038/ejhg.2013.160

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Loss of mTOR complex 1 induces developmental blockage in early T-lymphopoiesis and eradicates T-cell acute lymphoblastic leukemia cells.2014

    • Author(s)
      Hoshii T, Kasada A, Hatakeyama T, Ohtani M, Tadokoro Y, Naka K, Ikenoue T, Ikawa T, Kawamoto H, Fehling HJ, Araki K, Yamamura K, Matsuda S, Hirao A
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 111 Pages: 3805-10

    • DOI

      10.1073/pnas.1320265111

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Circulating AIM Prevents Hepatocellular Carcinoma through Complement Activation2014

    • Author(s)
      Maehara N, Arai S, Mori M, Iwamura Y, Kurokawa J, Kai T, Kusunoki S, Taniguchi K, Ikeda K, Ohara O, Yamamura K, Miyazaki T
    • Journal Title

      Cell Report

      Volume: 9 Pages: 61-74

    • DOI

      10.1016/j.celrep.2014.08.058

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Disruption of actin-binding domain-containing Dystonin protein causes dystonia musculorum in mice.2014

    • Author(s)
      Horie, M., Watanabe, K., Bepari, A. K., Nashimoto, J., Araki, K., Sano, H., Chiken, S., Nambu, A., Ono, K., Ikenaka, K., Kakita, A., Yamamura, K. and Takebayashi, H.
    • Journal Title

      Eur. J. Neurocsi

      Volume: 40 Pages: 3458-3471

    • DOI

      10.1111/ejn.12711

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Circulating AIM as an Indicator of Liver Damage and Hepatocellular Carcinoma in Humans2014

    • Author(s)
      Yamazaki T, Mori M, Arai S, Tateishi R, Abe M, Ban M, Nishijima A, Maeda M, Asano T, Kai T, Izumino K, Takahashi J, Aoyama K, Harada S, Takebayashi T, Gunji T, Ohnishi S, Seto S, Yoshida Y, Hiasa Y, Koike K, Yamamura K, Inoue K, Miyazaki T
    • Journal Title

      Plos One

      Volume: 9

    • DOI

      10.1371/journal.pone.0109123

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Database for exchangeable gene trap clones: Pathway and gene ontology analysis of exchangeable gene trap clone mouse lines.2014

    • Author(s)
      Araki, M., Nakahara, M., Muta, M., Itou, M., Yanai, C., Yamazoe, F., Miyake, M., Morita, A., Araki, M., Okamoto, Y., Nakagata, M., Yoshinobu, K., Yamamura, K. and Araki, K.
    • Journal Title

      Develop. Growth Differ

      Volume: 56 Pages: 161-174

    • DOI

      10.1111/dgd.12116

    • NAID

      40019987325

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Screening Methods to Identify TALEN-Mediated Knockout Mice2014

    • Author(s)
      Nakagawa, Y., Yamamoto, T., Suzuki, K., Araki, K., Takeda, N., Ohmuraya, M. and Sakuma, T.
    • Journal Title

      Exp. Anim.

      Volume: 63

    • NAID

      130003391606

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Role of blood ribosomal protein S19 in coagulum resorption: a study using Gln137Glu-ribosomal protein S19 gene knock-in mouse.2014

    • Author(s)
      Chen, J., Fujino, R., Zhao, R., Semba, U., Araki, K. and Yamamoto, T.
    • Journal Title

      Pathol. Int.

      Volume: 64 Pages: 543-550

    • DOI

      10.1111/pin.12208

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Conformational change in transfer RNA is an early indicator of acute cellular damage.2014

    • Author(s)
      Mishima E, Inoue C, Saigusa D 他33名中13番目
    • Journal Title

      J. Am. Soc. Nephrol

      Volume: 25 Pages: 2316-2326

    • DOI

      10.1681/asn.2013091001

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Impaired degradation of WNK1 and WNK4 kinases causes PHAII in mutant KLHL3 knock-in mice2014

    • Author(s)
      Susa K, Sohara E, Rai T, Zeniya M, Mori Y, Mori T, Chiga M, Nomura N, Nishida H, Takahashi D, Isobe K, Inoue Y, Takeishi K, Takeda N, Sasaki S, Uchida S
    • Journal Title

      Hum Mol Genet.

      Volume: 23 (19) Pages: 5052-5060

    • DOI

      10.1093/hmg/ddu217

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Novel retinoblastoma mutation abrogating the interaction to E2F2/3, but not E2F1, led to selective suppression of thyroid tumors.2014

    • Author(s)
      Toki H, Inoue M, Minowa O, Motegi H, Saiki Y, Wakana S, Masuya H, Gondo Y, Shiroishi T, Yao R, Noda T
    • Journal Title

      Cancer Sci

      Volume: 105 Pages: 1360-1368

    • DOI

      10.1111/cas.12495

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Deficiency of Transcription Factor Brn4 Disrupts Cochlear Gap Junction Plaques in a Model of DFN3 Non-Syndromic Deafness.2014

    • Author(s)
      Kidokoro Y, Karasawa K, Minowa O, Sugitani Y., Noda T, Ikeda K, Kamiya K.
    • Journal Title

      PLoS One

      Volume: 9(9) Issue: 9

    • DOI

      10.1371/journal.pone.0108216

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Assembly of the cochlear gap junction macromolecular complex requires connexin 26.2014

    • Author(s)
      Kamiya K, Yum SW, Kurebayashi N, Muraki M, Ogawa K, Karasawa K, Miwa A, Guo X, Gotoh S, Sugitani Y, Yamanaka H, Ito-Kawashima S, Iizuka T, Sakurai T, Noda T, Minowa O, Ikeda K.
    • Journal Title

      Journal of Clinical Investigation

      Volume: 124 Issue: 4 Pages: 1598-1607

    • DOI

      10.1172/jci67621

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Identification of genomic locus responsible for experimentally induced testicular teratoma 1 (ett1) on mouse Chr 182014

    • Author(s)
      Miyazaki T, Ikeda Y, Kubo I, Suganuma S, Fujita N, Itakura M, Hayashi T, Takabayashi S, Katoh H, Ohira Y, Sato M, Noguchi M, Tokumoto T
    • Journal Title

      Mammalian Genome

      Volume: 25 Pages: 317-326

    • DOI

      10.1007/s00335-014-9529-8

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Contemporary techniques for freezing mouse spermatozoa2014

    • Author(s)
      Guan, M., Bogani D., Marschall, S., Raspa M., Takeo, T., Nakagata, N., Taft, R. and Fray, M.
    • Journal Title

      Curr Protoc Mouse Biol

      Volume: 4 Issue: 3

    • DOI

      10.1002/9780470942390.mo140065

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In vitro fertilization in mice using the MBCD-GSH protocol2014

    • Author(s)
      Guan, M., Bogani, D., Marschall, S., Raspa, M., Takeo, T., Nakagata, N. and Fray, M.
    • Journal Title

      Curr Protoc Mouse Biol

      Volume: 4 Issue: 2

    • DOI

      10.1002/9780470942390.mo140059

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Transporting mouse embryos and germplasm as frozen or unfrozen materials2014

    • Author(s)
      Kenyon, J., Guan, M., Bogani, D., Marschall, S., Raspa, M., Pickard, A., Takeo, T., Nakagata, N. and Fray, M.
    • Journal Title

      Curr Protoc Mouse Biol

      Volume: 4 Issue: 2

    • DOI

      10.1002/9780470942390.mo140064

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Conservation of mouse models through embryo freezing2014

    • Author(s)
      Guan, M, Bogani, D, Marschall, S, Raspa, M, Takeo, T, Nakagata, N, Fray, M
    • Journal Title

      Curr Protoc Mouse Biol

      Volume: 4 Issue: 4

    • DOI

      10.1002/9780470942390.mo140082

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rescue in vitro fertilization method for legacy stock of frozen mouse sperm2014

    • Author(s)
      Nakagata, N, Takeo, T, Fukumoto, K, Haruguchi, Y, Kondo, T, Takeshita, Y, Nakamuta, Y, Umeno, T, Tsuchiyama, S
    • Journal Title

      J Reprod Dev

      Volume: 60 Issue: 2

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Application of oocyte cryopreservation technology in TALEN-mediated mouse genome editing2014

    • Author(s)
      Nakagawa, Y., Sakuma, T., Nakagata, N., Yamasaki, S., Takeda, N., Ohmuraya, M. and Yamamoto, T.
    • Journal Title

      Exp Anim

      Volume: 63 Issue: 3

    • NAID

      130004677827

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Histological detection of catalytic ferrous iron with the selective turn-on fluorescent probe RhoNox-1 in a Fenton reaction-based rat renal carcinogenesis model.2014

    • Author(s)
      Mukaide T, Hatori Y, Misawa N, Funahashi S, Jiang L, Hirayama T, Nagasawa H,Toyokuni S
    • Journal Title

      Free Radical Research

      Volume: 48 Pages: 990-5

    • DOI

      10.3109/10715762.2014.898844

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Connective tissue growth factor and β-catenin constitute an autocrine loop for activation in rat sarcomatoid mesothelioma2014

    • Author(s)
      Jiang L, Yamashita Y, Chew SH, Akatsuka S, Ukai S, Wang S, Nagai H, Okazaki Y, Takahashi T, Toyokuni S
    • Journal Title

      J Pathol.

      Volume: 233 Pages: 402-14

    • DOI

      10.1002/path.4377

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Hsc70 contributes to cancer cell survival by preventing Rab1A degradation under stress conditions.2014

    • Author(s)
      Tanaka M, Mun S, Harada A, Ohkawa Y, Inagaki A, Sano S, Takahashi K, Izumi Y, Osada-Oka M, Wanibuchi H, Yamagata M, Yukimura T, Miura K, Shiota M, Iwao H.
    • Journal Title

      PLoS One.

      Volume: 9

    • DOI

      10.1371/journal.pone.0096785

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Inhibitory effect of raphanobrassica on Helicobacter pylori-induced gastritis in Mongolian gerbils.2014

    • Author(s)
      Yamada T, Wei M, Toyoda T, Yamano S, Wanibuchi H.
    • Journal Title

      Food Chem Toxicol

      Volume: 70 Pages: 107-113

    • DOI

      10.1016/j.fct.2014.04.037

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genotoxicity and subacute toxicity studies of a new astaxanthin-containing Phaffia rhodozyma extract2014

    • Author(s)
      Tago, Y, Fujii, T, Wada, J, Kato, M, Wei, M, Wanibuchi, H, Kitano, M
    • Journal Title

      J Toxicol Sci

      Volume: 39

    • NAID

      130004447121

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Valerian Inhibits Rat Hepatocarcinogenesis by Activating GABA(A) Receptor-Mediated Signaling.2014

    • Author(s)
      Kakehashi A., Kato A., Ishii N., Wei M., Morimura K., Fukushima S., Wanibuchi H.
    • Journal Title

      PLoS One

      Volume: 9

    • DOI

      10.1371/journal.pone.0113610

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Establishment of neutralizing rat monoclonal antibodies for fibroblast growth factor-22014

    • Author(s)
      Tanaka M, Yamaguchi M, Shiota M, Kawamoto Y, Takahashi K, Inagaki A, Osada-Oka M, Harada A, Wanibuchi H, Izumi Y, Miura K, Iwao H, Ohkawa Y.
    • Journal Title

      Monoclon Antib Immunodiagn Immunother.

      Volume: 33 Pages: 261-269

    • DOI

      10.1089/mab.2013.0085

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Comparative proteomics analysis of gastric cancer stem cells2014

    • Author(s)
      Morisaki T, Yashiro M, Kakehashi A, Inagaki A, Kinoshita H, Fukuoka T, Kasashima H, Masuda G, Sakurai K, Kubo N, Muguruma K, Ohira M, Wanibuchi H, Hirakawa K.
    • Journal Title

      PLoS One

      Volume: 9

    • DOI

      10.1371/journal.pone.0110736

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Nanosized zinc oxide particles do not promote DHPN-induced lung carcinogenesis but cause reversible epithelial hyperplasia of terminal bronchioles.2014

    • Author(s)
      Xu, J., Futakuchi, M., Alexander, D. B., Fukamachi, K., Numano, T., Suzui, M., Shimizu, H., Omori, T., Kanno, J., Hirose, A., and Tsuda, H.
    • Journal Title

      Arch Toxicol

      Volume: 88 Pages: 65-75

    • DOI

      10.1007/s00204-013-1086-5

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Size- and shape-dependent pleural translocation, deposition, fibrogenesis, and mesothelial proliferation by multiwalled carbon nanotubes.2014

    • Author(s)
      Xu, J., Alexander, D. B., Futakuchi, M., Numano, T., Fukamachi, K., Suzui, M., Omori, T., Kanno, J., Hirose, A., and Tsuda, H.
    • Journal Title

      Cancer Sci

      Volume: 105 Pages: 763-769

    • DOI

      10.1111/cas.12437

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Comparative study of toxic effects of anatase and rutile type nanosized titanium dioxide particles in vivo and in vitro2014

    • Author(s)
      Numano, T., Xu, J., Futakuchi, M., Fukamachi, K., Alexander, D.B., Furukawa, F., Kanno, J., Hirose, A., Tsuda, H., and Suzui, M
    • Journal Title

      Asian Pacific J Cancer Prev

      Volume: 15

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rat N-ERC/mesothelin as a marker for in vivo screening of drugs against pancreas cancer2014

    • Author(s)
      Fukamachi K, Iigo M, Hagiwara Y, Shibata K, Futakuchi M, Alexander DB, Hino O, Suzui M, Tsuda H.
    • Journal Title

      Plos One

      Volume: 9 Pages: 268-274

    • DOI

      10.1371/journal.pone.0111481

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Significance of the progesterone receptor and epidermal growth factor receptor, but not the estrogen receptor, in chemically induced lung carcinogenesis in female A/J mice2014

    • Author(s)
      Kishi S, Yokohira M, Yamakawa K, Saoo K, Imaida K
    • Journal Title

      Oncol. Lett

      Volume: 8

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Napsin A is possibly useful marker to predict the tumorigenic potential of lung bronchiolo-alveolar hyperplasia in F344 rats.2014

    • Author(s)
      Yokohira M., Kishi S., Yamakawa K., Nakano Y., Ninomiya F., Kinouch S., Tanizawa J., Saoo K., Imaida K.
    • Journal Title

      Exp. Toxicol. Pathol

      Volume: 66 Pages: 117-23

    • DOI

      10.1016/j.etp.2013.11.002

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The Peroxisome Proliferator-Activated Receptor (PPAR) α Agonist Fenofibrate Suppresses Chemically Induced Lung Alveolar Proliferative Lesions in Male Obese Hyperlipidemic Mice2014

    • Author(s)
      Toshiya Kuno, Kazuya Hata, Manabu Takamatsu, Akira Hara, Yoshinobu Hirose, Satoru Takahashi, Katsumi Imaida, Takuji Tanaka
    • Journal Title

      Int. J. Mol. Sci

      Volume: 15 Pages: 9160-72

    • DOI

      10.3390/ijms15059160

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Immunohistochemical Characteristics of Surfactant Proteins A, B, C and D in Inflammatory and Tumorigenic Lung Lesions of F344 Rats2014

    • Author(s)
      Yokohira M, Yamakawa K, Nakano Y, Numano T, Furukawa F, Kishi S, Ninomiya F, Kanie S, Hitotsumachi H, Saoo K, Imaida K
    • Journal Title

      J Toxicol Pathol

      Volume: 27 Issue: 3+4 Pages: 175-182

    • DOI

      10.1293/tox.2014-0020

    • NAID

      130004713012

    • ISSN
      0914-9198, 1881-915X
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rat strain differences in levels and effects of chronic inflammation due to intratracheal instillation of quartz on lung tumorigenesis induced by DHPN2014

    • Author(s)
      Nakano Y, Yokohira M, Hashimoto N, Yamakawa K, Kishi S, Ninomiya F, Kanie S, Saoo K, Imaida K
    • Journal Title

      Exp. Toxicol. Pathol

      Volume: 66

    • DOI

      10.1016/j.etp.2014.06.002

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hepatoid giant cell tumor of tendon sheath-A rare morphologic variant case report2014

    • Author(s)
      Yoshimoto, T., Motoi, N., Kanda, H., Tanizawa, T., Shimoji, T., Matsumoto, S., Mukai, H., Ishikawa, Y., Machinami, R.
    • Journal Title

      Pathology Res. Practice

      Volume: 14

    • DOI

      10.1016/j.prp.2014.05.012

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Method for Cancer Diagnosis using DNA Ploidy Analysis with a Combination of Fast Fourier Transform and Domain Method2014

    • Author(s)
      日向奈恵、神田浩明、塩山高広、鈴木あかね、武田朴、石川雄一、山口俊晴、加藤洋
    • Journal Title

      TJSBME

      Volume: 52 Issue: 3 Pages: 136-144

    • DOI

      10.11239/jsmbe.52.136

    • NAID

      130004691214

    • ISSN
      1347-443X, 1881-4379
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Premature termination of reprogramming in vivo leads to cancer development through altered epigenetic regulation.2014

    • Author(s)
      Ohnishi K, Semi K, Yamamoto T, Shimizu M, Tanaka A, Mitsunaga K, Okita K, Osafune K, Arioka Y, Maeda T, Soejima H, Moriwaki H, Yamanaka S, Woltjen K, Yamada Y.
    • Journal Title

      Cell

      Volume: 156 Pages: 663-677

    • DOI

      10.1016/j.cell.2014.01.005

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer2014

    • Author(s)
      Al Olama, A.A., Kote-Jarai Z., Bemdt S.I., Conti D.V., Schumacher F., Han Y., Benlloch S., Hazelett D.J., Wang Z., Saunders E., Leongamornlert D., Lindstrom S., Jugurnauth-Little S., Dadaev T., Tymrakiewicz M., Stram D.O., Rand K., Wan P., Stram A., Kubo M., et al.
    • Journal Title

      Nat Genet

      Volume: 46

    • DOI

      10.1038/ng.3094

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Infection with Porphyromonas gingivalis exacerbates endothelial injury in obese mice.2014

    • Author(s)
      Ao, M., Miyauchi, M., Inubushi, T., Kitagawa, M., Furusho, H., Ando, T., Ayuningtyas, N.F., Nagasaki, A., Ishihara, K., Tahara, H., Kozai, K. & Takata, T.
    • Journal Title

      PLoS One

      Volume: 9

    • DOI

      10.1371/journal.pone.0110519

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Development of a SNP set for human identification : A set with high powers of discrimination which yields high genetic information from naturally degraded DNA samples in the Thai population2014

    • Author(s)
      Boonyarit, H., Mahasirimongkol S., Chavalvechakul N., Aoki M., Amitani H., Hosono N., Kamatani N., Kubo M. and Lertrit P.
    • Journal Title

      Forensic Sci Int Genet

      Volume: 11

    • DOI

      10.1016/j.fsigen.2014.03.010

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1,5q14.3 and 15q26.12014

    • Author(s)
      Cai, Q., Zhang B., Sung H., Low S.K., Kweon S.S., Shen C.Y., Matsuo K., Teo S.H., Kim M.K., Iwasaki M., Hartman M., Takahashi A., Ashikawa K., Matsuda K., Ito H., Kasuga Y., Iwata H., Tsugane S., Nakamura Y., Kubo M., et al.
    • Journal Title

      Nat Genet

      Volume: 46

    • DOI

      10.1038/ng.3041

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians.2014

    • Author(s)
      Chen P, Takeuchi F, Lee JY,.., Kita Y, et al
    • Journal Title

      Diabetes

      Volume: 63(7) Pages: 2551-2562

    • DOI

      10.2337/db13-1815

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101 (Alliance).2014

    • Author(s)
      Chhibber A, Mefford J, Zembutsu H et al
    • Journal Title

      Pharmacogenomics J

      Volume: 14 Pages: 336-342

    • DOI

      10.1038/tpj.2014.2

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Establishment of CYP2D6 reference samples by multiple validated genotyping platforms2014

    • Author(s)
      Fang, H., Liu X., Ramirez J., Choudhury N., Kubo M., Im H.K., Konkashbaev A., Cox N.J., Ratain M.J., Nakamura Y. and O'Donnell P.H.
    • Journal Title

      Pharmacogenomics J

      Volume: 14

    • DOI

      10.1038/tpj.2014.27

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genetic variants in transcription factors are associated with the pharmacokinetics and pharmacodynamics of metformin2014

    • Author(s)
      Goswami, S., Yee S.W., Stocker S., Mosley J.D., Kubo M., Castro R., Mefford J.A., Wen C., Liang X., Witte J., Brett C., Maeda S., Simpson M.D., Hedderson M.M., Davis R.L., Roden D.M., Giacomini K.M. and Savic R.M.
    • Journal Title

      Clin Pharmacol Ther

      Volume: 96

    • DOI

      10.1038/clpt.2014.109

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A novel RET rearrangement (ACBD5/RET) by pericentric inversion, inv(10)(p12.1 ; q11.2), in papillary thyroid cancer from an atomic bomb survivor exposed to high-dose radiation2014

    • Author(s)
      Hamatani, K., Eguchi H., Koyama K., Mukai M., Nakachi K. and Kusunoki Y.
    • Journal Title

      Oncol Rep

      Volume: 32

    • DOI

      10.3892/or.2014.3449

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Associations between hOGG1 Ser326Cys polymorphism and increased body mass index and fasting glucose level in the Japanese general population2014

    • Author(s)
      Hara, M., Nakamura K., Nanri H., Nishida Y., Hishida A., Kawai S., Hamajima N., Kita Y., Suzuki S., Mantjoro E.M., Ohnaka K., Uemura H., Matsui D., Oze I., Mikami H., Kubo M., Tanaka H. and Japan Multi-Institutional Collaborative Cohort Study Group
    • Journal Title

      J Epidemiol

      Volume: 24

    • NAID

      130004449419

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cancer Philosophy~Thinking“Cancer Cells”Deeply2014

    • Author(s)
      Hino, O
    • Journal Title

      Juntendo Medical Journal

      Volume: 60

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Telomeric g-tail length and hospitalization for cardiovascular events in hemodialysis patients.2014

    • Author(s)
      Hirashio, S., Nakashima, A., Doi, S., Anno, K., Aoki, E., Shimamoto, A., Yorioka, N., Kohno, N., Masaki, T. & Tahara, H.
    • Journal Title

      Clinical journal of the American Society of Nephrology : CJASN

      Volume: CJASN 9 Pages: 2117-2122

    • DOI

      10.2215/cjn.10010913

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Retrospective analysis of large-scale research screening of construction workers for the early diagnosis of mesothelioma.2014

    • Author(s)
      Hirohashi T, Igarashi K, Abe M, Hino O et al.
    • Journal Title

      Mol Clin Oncol

      Volume: 2 Pages: 26-30

    • DOI

      10.3892/mco.2013.197

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] CBP-93872 inhibits NBS1-mediated ATR activation, abrogating maintenance of the DNA double-strand break-specific G2 checkpoint.2014

    • Author(s)
      Hirokawa T, Shiotani B, Shimada M, Murata K, Johmura Y, Haruta M, Tahara H, Takeyama H, Nakanishi M.
    • Journal Title

      Cancer Research

      Volume: 74 Pages: 3880-3889

    • DOI

      10.1158/0008-5472.can-13-3604

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] GCK, GCKR polymorphisms and risk of chronic kidney disease in Japanese individuals: data from the J-MICC Study.2014

    • Author(s)
      Hishida A, Takashima N, Turin TC, Kawai S, Wakai K, Hamajima N, Hosono S, Nishida Y, Suzuki S, Nakahata N, Mikami H, Ohnaka K, Matsui D, Katsuura-Kamano S, Kubo M, Tanaka H, Kita Y.
    • Journal Title

      Journal of nephrology

      Volume: 27(2) Pages: 143-149

    • DOI

      10.1007/s40620-013-0025-0

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Polymorphisms of genes involved in lipid metabolism and risk of chronic kidney disease in Japanese - cross-sectional data from the J-MICC study.2014

    • Author(s)
      Hishida A, Wakai K, Naito M, Suma S, Sasakabe T, Hamajima N, Hosono S, Horita M, Turin TC, Suzuki S, Kairupan TS, Mikami H, Ohnaka K, Watanabe I, Uemura H, Kubo M, Tanaka H; J-MICC Study Group.
    • Journal Title

      Lipids Health Dis

      Volume: 13 Pages: 162-162

    • DOI

      10.1186/1476-511x-13-162

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] TERT attenuated ER stress-induced cell death.2014

    • Author(s)
      Hosoi, T., Inoue, Y., Nakatsu, K., Matsushima, N., Kiyose, N., Shimamoto, A., Tahara, H. & Ozawa, K.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 447 Pages: 378-382

    • DOI

      10.1016/j.bbrc.2014.04.034

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Circulating tumor cell count during zoledronic acid treatment in men with metastatic prostate cancer : a pilot study2014

    • Author(s)
      Ide, H., Lu Y., Tanaka T., Wakumoto Y., Kitamura K., Muto S., Yamaguchi R., Masumori N. and Horie S.
    • Journal Title

      Prostate Int

      Volume: 2

    • DOI

      10.12954/pi.14056

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Asbestos-related mesothelioma : Prevention, early detection, treatment2014

    • Author(s)
      Imai, M. and Hino O.
    • Journal Title

      JSM Clinical Oncology and Research

      Volume: 2 Issue: 3

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ERC/mesothelin is expressed in human gastric cancer tissues and cell lines.2014

    • Author(s)
      Ito T, Kajino K, Abe M, Hino O et al.
    • Journal Title

      Oncol Rep

      Volume: 31 Pages: 27-33

    • DOI

      10.3892/or.2013.2803

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association of EPAS1 gene rs4953354 polymorphism with susceptibility to lung adenocarcinoma in female Japanese non-smokers2014

    • Author(s)
      Iwamoto, S., Tanimoto K., Nishio Y., Putra A.C., Fuchita H., Ohe M., Sutani A., Kuraki T., Hiyama K., Murakami I., Eguchi H. and Isobe T.
    • Journal Title

      J Thorac Oncol

      Volume: 9

    • DOI

      10.1097/jto.0000000000000309

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Citalopram and escitalopram plasma drug and metabolite concentrations : genome-wide associations2014

    • Author(s)
      Ji, Y., Schaid D.J., Desta Z., Kubo M., Batzler A.J., Snyder K., Mushiroda T., Kamatani N., Ogburn E., Hall-Flavin D., Flockhart D., Nakamura Y., Mrazek D.A. and Weinshilboum R.M.
    • Journal Title

      Br J Clin Pharmacol

      Volume: 78

    • DOI

      10.1111/bcp.12348

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] EP2 signaling mediates suppressive effects of celecoxib on androgen receptor expression and cell proliferation in prostate cancer2014

    • Author(s)
      Kashiwagi E, Shiota M, *Yokomizo A, Inokuchi J, Uchiumi T, Naito S.
    • Journal Title

      Prostate Cancer Prostatic Dis

      Volume: 17 Pages: 10-17

    • DOI

      10.1038/pcan.2013.53

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] A polymorphism near MC4R gene (rs17782313) is associated with serum triglyceride levels in the general Japanese population: the J-MICC Study.2014

    • Author(s)
      Katsuura-Kamano S, Uemura H, Arisawa K, Yamaguchi M, Hamajima N, Wakai K, Okada R, Suzuki S, Taguchi N, Kita Y, Ohnaka K, Kairupan TS, Matsui D, Oze I, Mikami H, Kubo M, Tanaka H.
    • Journal Title

      Endocrine

      Volume: 47 Pages: 81-89

    • DOI

      10.1007/s12020-014-0306-y

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Trans-ethnic meta-analysis of white blood cell phenotypes2014

    • Author(s)
      Keller, M.F., Reiner A.P., Okada Y., van Rooij F.J., Johnson A.D., Chen M.H., Smith A.V., Morris A.P., Tanaka T., Ferrucci L., Zonderman A.B., Lettre G., Kamatani Y., Matsuda K., Kamatani N., Nakamura Y., Kubo M., Takahashi A., Wilson J.G., BioBank Japan Project Working Groups, et al.
    • Journal Title

      Hum Mol Genet

      Volume: 23

    • DOI

      10.1093/hmg/ddu401

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] SOD3 acts as a tumor suppressor in PC-3 prostate cancer cells via hydrogen peroxide accumulation2014

    • Author(s)
      Kim, J., Mizokami A., Shin M., Izumi K., Konaka H., Kadono Y., Kitagawa Y., Keller E.T., Zhang J. and Namiki M.
    • Journal Title

      Anticancer Res

      Volume: 34

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A genome-wide association study to identify genomic modulators of rate control therapy in patients with atrial fibrillation2014

    • Author(s)
      Kolek, M.J., Edwards T.L., Muhammad R., Balouch A., Shoemaker M.B., Blair M.A., Kor K.C., Takahashi A., Kubo M., Roden D.M., Tanaka T. and Darbar D.
    • Journal Title

      Am J Cardiol

      Volume: 114

    • DOI

      10.1016/j.amjcard.2014.05.040

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Combination of Bevacizumab and Acyclic Retinoid Inhibits the Growth of Hepatocellular Carcinoma Xenografts2014

    • Author(s)
      Kubota M, Shimizu M, Baba A, Ohno T, Kochi T, Shirakami Y, Moriwaki H.
    • Journal Title

      J Nutr Sci Vitaminol

      Volume: 60 Issue: 5 Pages: 357-362

    • DOI

      10.3177/jnsv.60.357

    • NAID

      130004773635

    • ISSN
      0301-4800, 1881-7742
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Aromatase inhibitor-associated bone fractures : a case-cohort GWAS and functional genomics2014

    • Author(s)
      Liu, M., Goss P.E., Ingle J.N., Kubo M., Furukawa Y., Batzler A., Jenkins G.D., Carlson E.E., Nakamura Y., Schaid D.J., Chapman J.A., Shepherd L.E., Ellis M.J., Khosla S., Wang L. and Weinshilboum R.M.
    • Journal Title

      Mol Endocrinol

      Volume: 28

    • DOI

      10.1210/me.2014-1147

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles.2014

    • Author(s)
      Lotvall, J., Hill, A.F., Hochberg, F., Buzas, E.I., Di Vizio, D., Gardiner, C., Gho, Y.S., Kurochkin, I.V., Mathivanan, S., Quesenberry, P., Sahoo, S., Tahara, H., Wauben, M.H., Witwer, K.W. & Thery, C.
    • Journal Title

      J Extracell Vesicles

      Volume: 3 Pages: 26913-26913

    • DOI

      10.3402/jev.v3.26913

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Genome-wide association study : a useful tool to identify common genetic variants associated with drugtoxicity and efficacy in cancer pharmacogenomics2014

    • Author(s)
      Low, S.K., Takahashi A., Mushiroda T. and Kubo M.
    • Journal Title

      Clin Cancer Res

      Volume: 20

    • DOI

      10.1158/1078-0432.ccr-13-2755

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese2014

    • Author(s)
      Lubitz, S.A., Lunetta K.L., Lin H., Arking D.E., Trompet S., Li G., Krijthe B.P., Chasman D.I., Barnard J., Kleber M.E., Dorr M., Ozaki K., Smith A.V., Muller-Nurasyid M., Walter S., Agarwal S.K., Kubo M., Tanaka T., Heckbert S.R., Jukema J.W., et al.
    • Journal Title

      J Am Coll Cardiol

      Volume: 63

    • DOI

      10.1016/j.jacc.2013.12.015

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ethical challenges for the design and conduct of mega-biobanking from Great East Japan Earthquake victims2014

    • Author(s)
      Matsui, K. and Tashiro S.
    • Journal Title

      BMC Med Ethics

      Volume: 15

    • DOI

      10.1186/1472-6939-15-55

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] DSE-FRET : A new anticancer drug screening assay for DNA binding proteins2014

    • Author(s)
      Miyagi T, Shiotani B, Miyoshi R, Yamamoto T, Oka T, Umezawa K, Ochiya T, Takano M, Tahara H
    • Journal Title

      Cancer Science

      Volume: (in press) Pages: 870-874

    • DOI

      10.1111/cas.12420

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Proposed salvage treatment strategy for biochemical failure after radical prostatectomy in patients with prostate cancer : a retrospective study2014

    • Author(s)
      Miyake, M., Tanaka N., Asakawa I., Morizawa Y., Anai S., Torimoto K., Aoki K., Yoneda T., Hasegawa M., Konishi N. and Fujimoto K.
    • Journal Title

      Radiat Oncol

      Volume: 9

    • DOI

      10.1186/1748-717x-9-208

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Photodynamic diagnosis of shed prostate cancer cells in voided urine treated with 5-aminolevulinic acid.2014

    • Author(s)
      Nakai Y, Anai S, Kuwada M, Miyake M, Chihara Y, Tanaka N, Hirayama A, Yoshida K, Hirao Y, Fujimoto K.
    • Journal Title

      BMC Urol

      Volume: 3

    • DOI

      10.1186/1471-2490-14-59

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A genome-wide association study identifies susceptibility loci for ossification of the posterior longitudinal ligament of the spine.2014

    • Author(s)
      Nakajima M, Takahashi A, Tsuji T, Furukawa K-I et al.
    • Journal Title

      Nat Genet

      Volume: 46 Pages: 1012-1016

    • DOI

      10.1038/ng.3045

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Common dysfunctional variants of ABCG2 have stronger impact on hyperuricemia progression than typical environmental risk factors.2014

    • Author(s)
      Nakayama A, et al.
    • Journal Title

      Sci Rep

      Volume: 4 Pages: 5227-5227

    • DOI

      10.1038/srep05227

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Objectively measured physical activity and inflammatory cytokine levels in middle-aged Japanese people.2014

    • Author(s)
      Nishida Y, Higaki Y, Taguchi N, Hara M, Nakamura K, Nanri H, Imaizumi T, Sakamoto T, Horita M, Shinchi K, Tanaka K.
    • Journal Title

      Prev Med

      Volume: 64 Pages: 81-87

    • DOI

      10.1016/j.ypmed.2014.04.004

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Association between KCNJ6 (GIRK2) gene polymorphism rs2835859 and post-operative analgesia, pain sensitivity, and nicotine dependence2014

    • Author(s)
      Nishizawa, D., Fukuda K., Kasai S., Ogai Y., Hasegawa J., Sato N., Yamada H., Tanioka F., Sugimura H., Hayashida M. and Ikeda K.
    • Journal Title

      J Pharmacol Sci

      Volume: 126

    • NAID

      130004700283

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Pyrrole-imidazole polyamide targeted to break fusion sites in TMPRSS2 and ERG gene fusion represses prostate tumor growth2014

    • Author(s)
      Obinata D, Ito Akiko, Fujiwara K, Takayama K, Ashikari D, Murata Y, Yamaguchi K, Urano T, Fujimura T, Fukuda N, Soma M, Watanabe T, Nagase H, Inoue S, Takahashi S
    • Journal Title

      Cancer Science

      Volume: 105 Pages: 1272-1278

    • DOI

      10.1111/cas.12493

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] interferon lambda 4/interleukin-28B haplotype structure and its impact on susceptibility to hepatitis C virus and treatment response in the Japanese population2014

    • Author(s)
      Ochi H, Miki D, Hayes CN, Abe H, Hayashida Y, Kubo M, Chayama K
    • Journal Title

      J Gen Virol

      Volume: 95巻 Pages: 1297-1306

    • DOI

      10.1099/vir.0.060103-0

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Genetics of rheumatoid arthritis contributes to biology and drug discovery.2014

    • Author(s)
      Okada Y, Wu D, Trynka G, Raj T, Terao C, Ikari K, Kochi Y, Ohmura K, Suzuki A, Yoshida S, Graham RR, Manoharan A, Ortmann W, Bhangale T, Denny JC, (省略), GARNET consortium, (以下省略).
    • Journal Title

      Nature

      Volume: 506 Pages: 376-381

    • DOI

      10.1038/nature12873

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Survey of survival among patients with hepatitis C virus-related hepatocellular carcinoma treated with peretinoin, an acyclic retinoid, after the completion of a randomized, placebo-controlled trial2014

    • Author(s)
      Okita, K., Izumi N., Ikeda K., Osaki Y., Numata K., Ikeda M., Kokudo N., Imanaka K., Nishiguchi S., Kondo S., Nishigaki Y., Shiomi S., Ueshima K., Isoda N., Karino Y., Kudo M., Tanaka K., Kaneko S., Moriwaki H., Makuuchi M., et al.
    • Journal Title

      J Gastroenterol

    • DOI

      10.1007/s00535-014-0996-1

    • Description
      Epub ahead of print
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Coffee and green tea consumption is associated with upper aerodigestive tract cancer in Japan2014

    • Author(s)
      Oze I, Matsuo K, Kawakita D, Hosono S, Ito H, Watanabe M, Hatooka S, Hasegawa Y, Shinoda M, Tajima K, Tanaka H.
    • Journal Title

      Int J Cancer

      Volume: 135 Issue: 2 Pages: 391-400

    • DOI

      10.1002/ijc.28653

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Higher levels of antibodies to the tumour-associated antigen cyclin B1 in cancer-free individuals than in patients with breast cancer2014

    • Author(s)
      Pandey, J.P., Kistner-Griffin E., Namboodiri A.M., Iwasaki M., Kasuga Y., Hamada G.S. and Tsugane S.
    • Journal Title

      Clin Exp Immunol

      Volume: 178

    • DOI

      10.1111/cei.12385

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genetic predictors associated with improvement of asthma symptoms in response to inhaled corticosteroids2014

    • Author(s)
      Park, H.W., Dahlin A., Tse S., Duan Q.L., Schuemann B., Martinez F.D., Peters S.P., Szefler S.J., Lima J.J., Kubo M., Tamari M. and Tantisira K.G.
    • Journal Title

      J Allergy Clin Immunol

      Volume: 133

    • DOI

      10.1016/j.jaci.2013.12.1042

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Acute case-fatality rates of stroke and acute myocardial infarction in a Japanese population: Takashima stroke and AMI registry, 1989-2005.2014

    • Author(s)
      Rumana N, Kita Y, Turin TC, Nakamura Y, Takashima N, Ichikawa M, Sugihara H, Morita Y, Hirose K, Kawakami K, Okayama A, Miura K, Ueshima H.
    • Journal Title

      Int J Stroke

      Volume: Supple A100 Pages: 69-75

    • DOI

      10.1111/ijs.12288

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] A common variant of organic anion transporter 4(OAT4/SLC22A11) gene is associated with renal underexcretion type gout2014

    • Author(s)
      Sakiyama, M., Matsuo H., Shimizu S., Nakashima H., Nakayama A., Chiba T., Naito M., Takada T., Suzuki H., Hamajima N., Ichida K., Shimizu T. and Shinomiya N.
    • Journal Title

      Drug Metab Pharmacokinet

      Volume: 29

    • NAID

      130004463357

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ethnic Differences in ATP-binding Cassette Transporter, Sub-family G, Member 2 (ABCG2/BCRP): Genotype Combinations and Estimated Functions2014

    • Author(s)
      Sakiyama M, et al.
    • Journal Title

      DMPK

      Volume: 29(6) Issue: 6 Pages: 490-2

    • DOI

      10.2133/dmpk.dmpk-14-sc-041

      10.2133/dmpk.DMPK-14-SC-041

    • NAID

      130004463408

    • ISSN
      1347-4367, 1880-0920
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Newly established ELISA for N-ERC/mesothelin improves diagnostic accuracy in patients with suspected pleural mesothelioma2014

    • Author(s)
      Sato, T., Suzuki Y., Mori T., Maeda M., Abe M., Hino O. and Takahashi K.
    • Journal Title

      Cancer Med

      Volume: 3

    • DOI

      10.1002/cam4.297

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The construction of risk prediction models using GWAS data and its application to a type 2 diabetes prospective cohort2014

    • Author(s)
      Shigemizu D, Abe T, Morizono T, Johnson TA, Boroevich KA, Hirakawa Y, Ninomiya T, Kiyohara Y, Kubo M, Nakamura Y, Maeda S, Tsunoda T
    • Journal Title

      PLoS One

      Volume: 9

    • DOI

      10.1371/journal.pone.0092549

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Reprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture2014

    • Author(s)
      Shimamoto A, Kagawa H, Zensho K, Sera Y, Kazuki Y, Osaki M, Oshimura M, Ishigaki Y, Hmasaki K, Kodama Y, Yuasa S, Fukuda K, Hirashima K, Seimiya H, Koyama H, Shimizu T, Takemoto M, Yokote K, Goto M, Tahara H.
    • Journal Title

      PLoS One.;

      Volume: 9 Pages: 1-13

    • DOI

      10.1371/journal.pone.0112900

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Gender-specific associations of perceived stress and coping strategies with C-reactive protein in middle-aged and older men and women2014

    • Author(s)
      Shimanoe C, Otsuka Y, Hara M, Nanri H, Nishida Y, Nakamura K, Higaki Y, Imaizumi T, Taguchi N, Sakamoto T, Horita M, Shinchi K, Tanaka K
    • Journal Title

      International journal of behavioral medicine

      Volume: 未定

    • DOI

      10.1007/s12529-013-9341-y

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Pharmaceutical and nutraceutical approaches for preventing liver carcinogenesis: chemoprevention of hepatocellular carcinoma using acyclic retinoid and branched-chain amino acids.2014

    • Author(s)
      Shimizu M, Shirakami Y, Hanai T, Imai K, Suetsugu A, Takai K, Shiraki M, Moriwaki H.
    • Journal Title

      Mol Nutr Food Res

      Volume: 58 Pages: 124-135

    • DOI

      10.1002/mnfr.201300538

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impaired 8-hydroxyguanine repair activity of MUTYH variant p. Arg109Trp found in a Japanese patient with early-onset colorectal cancer2014

    • Author(s)
      Shinmura, K., Goto, M., Tao, H., Kato, H., Suzuki, R., Nakamura, S., Matsuda, T., Yin, G., Morita, M., Kono, S., Sugimura, H.
    • Journal Title

      Oxid Med Cell Longev

      Volume: 2014 Pages: 617351-617351

    • DOI

      10.1155/2014/617351

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] RSPO fusion transcripts in colorectal cancer in Japanese population.2014

    • Author(s)
      Shinmura K, Kahyo T, Kato H, Igarashi H, Matsuura S, Nakamura S, Kurachi K, Nakamura T, Ogawa H, Funai K, Tanahashi M, Niwa H, Sugimura H.
    • Journal Title

      Mol Biol Rep

      Volume: 41 Pages: 5375-5384

    • DOI

      10.1007/s11033-014-3409-x

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] PLK4 overexpression and its effect on centrosome regulation and chromosome stability in human gastric cancer2014

    • Author(s)
      Shinmura K, Kurabe N, Goto M, Yamada H, Natsume H, Konno H, Sugimura H
    • Journal Title

      Mol Biol Rep

      Volume: 41 Pages: 6635-6644

    • DOI

      10.1007/s11033-014-3546-2

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Transgenic expression of the N525S-tuberin variant in Tsc2 mutant (Eker) rats causes dominant embryonic lethality.2014

    • Author(s)
      Shiono M., Kobayashi T., Takahashi R., Ueda M., Ishikawa C. and Hino O.
    • Journal Title

      Sci Rep

      Volume: 4 Pages: 5927-5927

    • DOI

      10.1038/srep05927

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The oncological outcomes and risk stratification in docetaxel chemotherapy for castration-resistant prostate cancer2014

    • Author(s)
      Shiota, M., Yokomizo A., Adachi T., Koga H., Yamaguchi A., Imada K., Takeuchi A., Kiyoshima K., Inokuchi J., Tatsugami K. and Naito S.
    • Journal Title

      Jpn J Clin Oncol

      Volume: 44

    • DOI

      10.1093/jjco/hyu081

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The feature of metabolic syndrome is a risk factor for biochemical recurrence after radical prostatectomy2014

    • Author(s)
      Shiota, M., Yokomizo A., Takeuchi A., Imada K., Kiyoshima K., Inokuchi J., Tatsugami K. and Naito S.
    • Journal Title

      J Surg Oncol

      Volume: 110

    • DOI

      10.1002/jso.23677

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Risk factors for febrile neutropenia in patients receiving docetaxel chemotherapy for castration-resistant prostate cancer2014

    • Author(s)
      Shiota, M., Yokomizo A., Takeuchi A., Imada K., Kiyoshima K., Inokuchi J., Tatsugami K. and Naito S.
    • Journal Title

      Support Care Cancer

      Volume: 22

    • DOI

      10.1007/s00520-014-2328-7

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Integrating genetic, transcriptional, and functional analyses to identify five novel genes for atrial fibrillation2014

    • Author(s)
      Sinner MF, Tucker N, Lunetta K, Ozaki K, Smith G, Trompet S, Bis J, Lin H, Chung M, Nielsen JB, Lubitz S, Krijthe B, Magnani J, Ye J, Gollob M, Tsunoda T, Müller-Nurasyid M, Lichtner P, Peters A, Dolmatova E, Kubo M, Smith J, Psaty B, Smith N, Jukema JW, Chasman D, Ebana Y, Furukawa T, et al. (他27名)
    • Journal Title

      Circulation

      Volume: 130 Pages: 1225-1235

    • DOI

      10.1161/circulationaha.114.009892

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Subtypes of metabolic syndrome and of other risk factors in Japanese women with erosive esophagitis2014

    • Author(s)
      Sogabe, M., Okahisa T., Yamanoi A. and Takayama T.
    • Journal Title

      Medicine (Baltimore)

      Volume: 93

    • DOI

      10.1097/md.0000000000000276

    • NAID

      120006995466

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] TCGA output and practice of gastric cancer2014

    • Author(s)
      Sugimura, H
    • Journal Title

      Translational Gastrointestinal Cancer

    • Description
      Publish Ahead of Print
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Counts of Slackia sp. strain NATTS in intestinal flora are correlated to serum concentrations of equol both in prostate cancer cases and controls in Japanese men2014

    • Author(s)
      Sugiyama, Y., Nagata Y., Fukuta F., Takayanagi A., Masumori N., Tsukamoto T., Akasaka H., Ohnishi H., Saito S., Miura T., Moriyama K., Tsuji H., Akaza H. and Mori M.
    • Journal Title

      Asian Pac J Cancer Prev

      Volume: 15

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A rare Japanese case with a NUT midline carcinoma in the nasal cavity : A case report with immunohistochemical and genetic analyses2014

    • Author(s)
      Suzuki S, Sugimura H et al.
    • Journal Title

      Pathol Res Pract.

      Volume: 210(6) Pages: 383-388

    • DOI

      10.1016/j.prp.2014.01.013

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Extensive goblet cell metaplasia of the peripheral lung may harbor precancerous molecular changes : comparison of two cases2014

    • Author(s)
      Tajima, S., Kurabe N., Okudela K., Yajima K., Takahashi T., Neyatani H., Sugimura H. and Koda K.
    • Journal Title

      Pathol Int

      Volume: 64

    • DOI

      10.1111/pin.12204

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Radiation-induced breast angiosarcoma with a confirmative feature of c-MYC amplification2014

    • Author(s)
      Tajima, S., Mochizuki R., Sugimura H. and Hoshi S.
    • Journal Title

      Jpn J Clin Oncol

      Volume: 44

    • DOI

      10.1093/jjco/hyu064

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Advances in cancer epidemiology in Japan.2014

    • Author(s)
      Tanaka H.
    • Journal Title

      Int J Cancer

      Volume: 134 Pages: 747-754

    • DOI

      10.1002/ijc.28519

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The biochemical recurrence-free rate in patients who underwent prostate low-dose-rate brachytherapy, using two different definitions2014

    • Author(s)
      Tanaka N, Asakawa I, Katayama E, Hirayama A, Hasegawa M, Konishi N, Fujimoto K
    • Journal Title

      Radiation Oncology

      Volume: 9(1) Pages: 107-107

    • DOI

      10.1186/1748-717x-9-107

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Use of alpha-1 adrenoceptor antagonists in patients who underwent low-dose-rate brachytherapy for prostate cancer-a randomized controlled trial of silodosin versus naftopidil2014

    • Author(s)
      Tanaka, N., Torimoto K., Asakawa I., Miyake M., Anai S., Hirayama A., Hasegawa M., Konishi N. and Fujimoto K.
    • Journal Title

      Radiat Oncol

      Volume: 9

    • DOI

      10.1186/s13014-014-0302-7

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nadir PSA level and time to nadir PSA are prognostic factors in patients with metastatic prostate cancer2014

    • Author(s)
      Tomioka, A., Tanaka N., Yoshikawa M., Miyake M., Anai S., Chihara Y., Okajima E., Hirayama A., Hirao Y. and Fujimoto K.
    • Journal Title

      BMC Urol

      Volume: 14

    • DOI

      10.1186/1471-2490-14-33

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Utility of PAX8 mouse monoclonal antibody in the diagnosis of thyroid, thymic, pleural, and lung tumors: a comparison with polyclonal PAX8 antibody.2014

    • Author(s)
      Toriyama A, Mori T, Sekine S, Yoshida A, Hino O, Tsuta K.
    • Journal Title

      Histopathology.

      Volume: On line Pages: 465-472

    • DOI

      10.1111/his.12405

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Body mass index and breast cancer risk in Japan: a pooled analysis of eight population-based cohort studies.2014

    • Author(s)
      Wada K, Nagata C, Tamakoshi A, Matsuo K, Oze I, Wakai K, Tsuji I, Sugawara Y, Mizoue T, Tanaka K, Iwasaki M, Inoue M, Tsugane S, Sasazuki S; Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan.
    • Journal Title

      Ann Oncol

      Volume: 25(2) Pages: 519-24

    • DOI

      10.1093/annonc/mdt542

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Sugars, sucrose and colorectal cancer risk: the Fukuoka colorectal cancer study.2014

    • Author(s)
      Wang Z, Uchida K, Ohnaka K, Morita M, Toyomura K, Kono S, Ueki T, Tanaka M, Kakeji Y, Maehara Y, Okamura T, Ikejiri K, Futami K, Maekawa T, Yasunami Y, Takenaka K, Ichimiya H, Terasaka R.
    • Journal Title

      Scand J Gastroenterol

      Volume: 49 Pages: 581-588

    • DOI

      10.3109/00365521.2013.822091

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Imputation and subset-based association analysis across different cancertypes identifies multiple independent risk loci in the TERT-CLPTMIL region onchromosome 5p15.332014

    • Author(s)
      Wang, Z., Zhu B., Zhang M., Parikh H., Jia J., Chung C.C., Sampson J.N., Hoskins J.W., Hutchinson A., Burdette L., Ibrahim A., Ito H., Kitahara C.M., Kohno T., Kunitoh H., Matsuo K., Niwa S., Shiraishi K., Tanaka H., Yatabe Y., et al.
    • Journal Title

      Hum Mol Genet

      Volume: 23

    • DOI

      10.1093/hmg/ddu363

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index.2014

    • Author(s)
      Wen W, Zheng W, Okada Y, Takeuchi F, Tabara Y, Ohkubo T, Takashima N, Miki T, et al.
    • Journal Title

      Hum Mol Genet.

      Volume: 23 Pages: 5492-5504

    • DOI

      10.1093/hmg/ddu248

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Sexy Small Copy Numbers in Hereditary Gastric Carcinogenesis2014

    • Author(s)
      Yamada, H., Sakamoto H. and Sugimura H.
    • Journal Title

      J of Gastrointestinal & Digestive System

      Volume: 4

    • DOI

      10.4172/2161-069x.1000205

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A rare polymorphic variant of NBS1 reduces DNA repair activity and elevates chromosomal instability2014

    • Author(s)
      Yamamoto, Y., Miyamoto M., Tatsuda D., Kubo M., Nakagama H., Nakamura Y., Satoh H., Matsuda K., Watanabe T. and Ohta T.
    • Journal Title

      Cancer Res

      Volume: 74

    • DOI

      10.1158/0008-5472.can-13-3037

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Generation of Human induced pluripotent Stem (iPS) cells in serum- and feeder-free defined culture and TGF-β1 regulation of pluripotency2014

    • Author(s)
      Yamasaki S, Taguchi Y, Shimamoto A, Mukasa H, Tahara H, Okamoto T.
    • Journal Title

      PlosONE

      Volume: 9(1) Pages: 1-12

    • DOI

      10.1371/journal.pone.0087151

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Activation of Rheb, but not of mTORC1, impairs spine synapse morphogenesis in tuberous sclerosis complex.2014

    • Author(s)
      Yasuda S, Sugiura H, Katsurabayashi S, Shimada T, Tanaka H, Takasaki K, Iwasaki K, Kobayashi T, Hino O, Yamagata K.
    • Journal Title

      Science Rep.

      Volume: 4 Pages: 5155-5155

    • DOI

      10.1038/srep05155

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Decreased amyloid-beta pathologies by intracerebral loading of glycosphingolipid-enriched exosomes in Alzheimer model mice.2014

    • Author(s)
      Yuyama, K., Sun, H., Sakai, S., Mitsutake, S., Okada, M., Tahara, H., Furukawa, J., Fujitani, N., Shinohara, Y. & Igarashi, Y.
    • Journal Title

      Journal of Biological Chemistry

      Volume: 289 Pages: 24488-24498

    • DOI

      10.1074/jbc.m114.577213

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk2014

    • Author(s)
      Zhang B, Jia WH, Matsuda K, Zheng W. et al.
    • Journal Title

      Nat Genet

      Volume: 46 Pages: 533-542

    • DOI

      10.1038/ng.2985

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians2014

    • Author(s)
      Zhang, B., Jia W.H., Matsuo K., Shin A., Xiang Y.B., Matsuda K., Jee S.H., Kim D.H., Cheah P.Y., Ren Z., Cai Q., Long J., Shi J., Wen W., Yang G., Ji B.T., Pan Z.Z., Matsuda F., Kubo M., Hosono S., et al.
    • Journal Title

      Int J Cancer

      Volume: 135

    • DOI

      10.1002/ijc.28733

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Burden of total and cause-specific mortality related to tobacco smoking among adults aged ≥ 45 years in Asia : a pooled analysis of 21 cohorts2014

    • Author(s)
      Zheng, W., McLerran D.F., Rolland B.A., Fu Z., Boffetta P., Tsugane S., Irie F., Tamakoshi A., Shu X.O., Ozasa K., Nishino Y., Tsuji I., Tanaka H., Sawada N., Ohishi W., Kakizaki M., Watanabe T., Oze I., Sugawara Y., Matsuo K., et al.
    • Journal Title

      PLoS Med

      Volume: 11

    • DOI

      10.1371/journal.pmed.1001631

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] クルクミンによるaryl hydrocarbon receptor(AhR)を介した発癌抑制機構2014

    • Author(s)
      井手久満、陸彦、杉浦正一郎、堀内明、古謝将之、中島晶子、井上正浩、野間康央、北村香介、常盤紫野、斎藤恵介、吉井隆、磯谷周治、山口雷藏、武藤智、堀江重郎
    • Journal Title

      日本腎泌尿器科疾患予防医学研究会誌

      Volume: 22

    • Related Report
      2014 Annual Research Report
  • [Journal Article] Establishing Statisticians Standards of Conduct— Background and Tasks for the Future2014

    • Author(s)
      佐藤恵子、岩崎学、菅波秀規、佐藤俊哉、椿広計
    • Journal Title

      JJB

      Volume: 35 Issue: 1 Pages: 37-53

    • DOI

      10.5691/jjb.35.37

    • NAID

      130004699703

    • ISSN
      0918-4430, 2185-6494
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] <b>Inalienable Right to Withdraw from Study and the Point of No Return in the Context of Biobank Research</b>2014

    • Author(s)
      松井健志、會澤久仁子、玉腰暁子
    • Journal Title

      Jpn. J. Clin. Pharmacol. Ther.

      Volume: 45 Issue: 1 Pages: 17-23

    • DOI

      10.3999/jscpt.45.17

    • NAID

      130004541576

    • ISSN
      0388-1601, 1882-8272
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 前立腺癌におけるがん幹細胞研究(特集去勢抵抗性前立腺癌 : 基礎と臨床の最新研究動向)--(前立腺癌の最新情報)2014

    • Author(s)
      西田幸代、舛森直哉
    • Journal Title

      日本臨床

      Volume: 72

    • NAID

      40020271103

    • Related Report
      2014 Annual Research Report
  • [Journal Article] バイオバンク2014

    • Author(s)
      増井徹
    • Journal Title

      シリーズ生命倫理学

      Volume: 11「遺伝子と医療」

    • Description
      (丸善出版)
    • Related Report
      2014 Annual Research Report
  • [Journal Article] On the regulation of human genome research-the use of genome information2014

    • Author(s)
      増井徹
    • Journal Title

      Organ Biology

      Volume: 21 Issue: 1 Pages: 16-23

    • DOI

      10.11378/organbio.21.16

    • NAID

      130003398821

    • ISSN
      1340-5152, 2188-0204
    • Related Report
      2014 Annual Research Report
  • [Journal Article] 遺伝子診断の未来と罠2014

    • Author(s)
      増井徹、齋藤加代子、菅野純夫
    • Journal Title

      こころの科学

      Volume: 増刊

    • Description
      (日本評論社)
    • Related Report
      2014 Annual Research Report
  • [Journal Article] 日本人閉経女性における肥満と骨質に関する検討(第15回日本骨粗鬆症学会)2014

    • Author(s)
      尾崎悦子、栗山長門、松井大輔
    • Journal Title

      オステオポローシスジャパン : 日本骨粗鬆症学会雑誌

      Volume: 22

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] HTLV-1 induces a Th1-like state in CD4+CCR4+ T cells.2014

    • Author(s)
      Araya N, Sato T, Ando H, Tomaru U, Yoshida M, Coler-Reilly A, Yagishita N, Yamauchi J, Hasegawa A, Kannagi M, Hasegawa Y, Takahashi K, Kunitomo Y, Tanaka Y, Nakajima T, Nishioka K, Utsunomiya A, Jacobson S, Yamano Y.
    • Journal Title

      J Clin Invest

      Volume: 124 Issue: 8 Pages: 3431-3442

    • DOI

      10.1172/jci75250

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Antitumor effects of bevacizumab in a microenvironment-dependent human adult T-cell leukemia/lymphoma mouse model2014

    • Author(s)
      Mori F, Ishida T, Ito A, Sato F, Masaki A, Narita T, Suzuki S, Yamada T, Takino H, Ri M, Kusumoto S, Komatsu H, Hishizawa M, Imada K, Takaori-Kondo A, Niimi A, Ueda R, Inagaki H, Iida S
    • Journal Title

      European journal of haematology

      Volume: 92 Pages: 219-228

    • DOI

      10.1111/ejh.12231

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reactivation of hepatitis B virus in a patient with adult T-cell leukemia/lymphoma receiving the anti-CC chemokine receptor 4 antibody mogamulizumab.2014

    • Author(s)
      Nakano N
    • Journal Title

      Hepatology research : the official journal of the Japan Society of Hepatology

      Volume: Epub ahead Pages: 354-357

    • DOI

      10.1111/hepr.12117

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] HTLV-1 bZIP factor-specific CD4 T cell responses in adult T cell leukemia/lymphoma patients after allogeneic hematopoietic stem cell transplantation.2014

    • Author(s)
      Narita T, Ishida T, Masaki A, Suzuki S, Ito A, Mori F, Yamada T, Ri M, Kusumoto S, Komatsu H, Miyazaki Y, Takatsuka Y, Utsunomiya A, Niimi A, Iida S, Ueda R.
    • Journal Title

      Journal of immunology

      Volume: 192 Pages: 940-947

    • DOI

      10.4049/jimmunol.1301952

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prognostic impact of miR-145 down-regulation in adult T-cell leukemia/ lymphoma2014

    • Author(s)
      Hongjing Xia, Seiji Yamada, Mineyoshi Aoyama, Fumihiko Sato, Ayako Masaki, Yan Ge, Masaki Ri, Takashi Ishida, Ryuzo Ueda, Atae Utsunomiya, Kiyofumi Asai, Hiroshi Inagaki
    • Journal Title

      Human pathology

      Volume: S0046-8177(14) Pages: 53-57

    • DOI

      10.1016/j.humpath.2014.01.017

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] HTLV-1 proviral integration sites differ between asymptomatic carriers and patients with HAM/TSP.2014

    • Author(s)
      Niederer HA, Laydon DJ, Melamed A, Elemans M, Asquith B, Matsuoka M, Bangham CR
    • Journal Title

      Virology J

      Volume: 11 Pages: 172-172

    • DOI

      10.1186/1743-422x-11-172

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A critical role for IL-17RB signaling in HTLV-1 Tax-induced NF-κB activation and T-cell transformation.2014

    • Author(s)
      Lavorgna A, Matsuoka M, Harhaj EW
    • Journal Title

      PLoS Pathogens

      Volume: 10

    • DOI

      10.1371/journal.ppat.1004418

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The role of HTLV-1 clonality, proviral structure and genomic integration site in adult T cell leukemia/lymphoma.2014

    • Author(s)
      Cook LB, Melamed A, Niederer H, Valganon M, Laydon D, Foroni L, Taylor GP, Matsuoka M, Bangham CR
    • Journal Title

      Blood

      Volume: 123 Pages: 3925-3931

    • DOI

      10.1182/blood-2014-02-553602

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Development of T cell lymphoma in HTLV-1 bZIP factor and Tax double transgenic mice.2014

    • Author(s)
      Zhao, T, Satou Y and Matsuoka M
    • Journal Title

      Arch Virol.

      Volume: 159 Pages: 1849-1856

    • DOI

      10.1007/s00705-014-2099-y

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Controlling leucine-zipper partner recognition in cells through modifications of a-g interactions.2014

    • Author(s)
      Azuma Y, Kükenshöner T, Ma G, Yasunaga JI, Imanishi M, Arndt KM, Matsuoka M, and Futaki S
    • Journal Title

      Chem Commun (Camb)

      Volume: 50 Pages: 6364-6367

    • DOI

      10.1039/c4cc00555d

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] HTLV-1 bZIP factor suppresses apoptosis by attenuating the function of FoxO3a and altering its localization.2014

    • Author(s)
      Tanaka-Nakanishi A, Yasunaga J-I, Takai K and Matsuoka M
    • Journal Title

      Cancer Research

      Volume: 74 Pages: 188-200

    • DOI

      10.1158/0008-5472.can-13-0436

    • NAID

      120005587789

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Human T-cell leukemia virus type 1 and Foxp3 expression: viral strategy in vivo.2014

    • Author(s)
      Miyazato P and Matsuoka M
    • Journal Title

      Int Immunol

      Volume: 26 Pages: 419-425

    • DOI

      10.1093/intimm/dxu048

    • NAID

      120005623226

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Cytotoxic T lymphocyte lysis of HTLV-1 infected cells is limited by weak HBZ protein expression, but non-specifically enhanced on induction of Tax expression2014

    • Author(s)
      Rowan AG, Suemori K, Fujiwara H, Yasukawa M, Tanaka Y, Taylor GP, Bangham C
    • Journal Title

      Retrovirology

      Volume: 11 Issue: 1

    • DOI

      10.1186/s12977-014-0116-6

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Downregulation of proapoptotic Bim augments IL-2-independent T-cell transformation by human T-cell leukemia virus type-1 Tax.2014

    • Author(s)
      Higuchi M, Takahashi M, Tanaka Y, Fujii M.
    • Journal Title

      Cancer Med

      Volume: 3 Issue: 6 Pages: 1605-1614

    • DOI

      10.1002/cam4.329

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] The neutralizing function of the anti-HTLV-1 antibody is essential in preventing in vivo transmission of HTLV-1 to human T cells in NOD-SCID/γcnull (NOG) mice.2014

    • Author(s)
      Saito M, Tanaka R, Fujii H, Kodama A, Takahashi Y, Matsuzaki T, Takashima H, Tanaka Y.
    • Journal Title

      Retrovirology

      Volume: 11 Issue: 1 Pages: 74-74

    • DOI

      10.1186/s12977-014-0074-z

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Epigenetic deregulation of Ellis Van Creveld confers robust Hedgehog signaling in adult T-cell leukemia2014

    • Author(s)
      Takahashi R; Yamagishi M, Nakano K, Yamochi T, Yamochi T, Fujikawa D, Nakashima M, Tanaka Y, Uchimaru K, Utsunomiya A, Watanabe T
    • Journal Title

      日本輸血細胞治療学会誌

      Volume: 105 Issue: 9 Pages: 1160-1169

    • DOI

      10.1111/cas.12480

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Epigenetic modification of the FoxP3 TSDR in HAM/TSP decreases the functional suppression of Tregs2014

    • Author(s)
      Anderson MR, Enose-Akahata Y, Massoud R, Ngouth N, Tanaka Y, Oh U, Jacobson S
    • Journal Title

      J Neuroimmune Pharmacol

      Volume: 9 Issue: 4

    • DOI

      10.1007/s11481-014-9547-z

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Elimination of human T cell leukemia virus type-1-infected cells by neutralizing and antibody-dependent cellular cytotoxicity-inducing antibodies against human T cell leukemia virus type-1 envelope gp46.2014

    • Author(s)
      Tanaka Y, Takahashi Y, Tanaka R, Kodama A, Fujii H, Hasegawa A, Kannagi M, Ansari AA, Saito M.
    • Journal Title

      AIDS Res Hum Retroviruses

      Volume: N/A Issue: 6 Pages: 542-552

    • DOI

      10.1089/aid.2013.0214

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] HTLV-1キャリアが産生するウイルス構造蛋白質に対する抗体と末梢血中のプロウイルス量に関する解析2014

    • Author(s)
      井上由紀子, 守田麻衣子, 後藤信代, 相良康子, 入田和男, 矢持忠徳, 渡邉俊樹, 岩永正子, 浜口功, 清川博之
    • Journal Title

      日本輸血細胞治療学会誌

      Volume: 60 Issue: 6

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development and validation of a new high-throughput method to investigate the clonality of HTLV-1-infected cells based on provirus integration sites.2014

    • Author(s)
      Firouzi S, Lopez Y, Suzuki Y, Nakai K, Sugano S, Yamochi T, Watanabe T.
    • Journal Title

      Genome Med

      Volume: 6(6) Issue: 6 Pages: 46-46

    • DOI

      10.1186/gm568

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] CADM1 expression and stepwise downregulation of CD7 are closely associated with clonal expansion of HTLV-I-infected cells in adult T-cell leukemia/lymphoma2014

    • Author(s)
      Kobayashi S, Nakano K, Watanabe E, Ishigaki T, Ohno N, Yuji K, Oyaizu N, Asanuma S, Yamagishi M, Yamochi T, Watanabe N, Tojo A, Watanabe T, Uchimaru K
    • Journal Title

      Clin Cancer Res

      Volume: 20(11) Issue: 11 Pages: 2851-2861

    • DOI

      10.1158/1078-0432.ccr-13-3169

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] High level of serum soluble interleukin-2 receptor at transplantation predicts poor outcome of allogeneic stem cell transplantation for adult T-cell leukemia2014

    • Author(s)
      Shigematsu A, Kobayashi N, Yasui H, Shindo M, Kakinoki Y, Koda K, Iyama S, Kuroda H, Tsutsumi Y, Imamura M, Teshima T
    • Journal Title

      Biol Blood Marrow Transplant

      Volume: 20 Pages: 801-805

    • DOI

      10.1016/j.bbmt.2014.02.014

    • NAID

      120005455889

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Epstein-Barr Virus-infected Cells in IgG4-related Lymphadenopathy With Comparison With Extranodal IgG4-related Disease.2014

    • Author(s)
      Takeuchi M, Sato Y, Yasui H, Ozawa H, Ohno K, Takata K, Gion Y, Orita Y, Tachibana T, Itoh T, Asano N, Nakamura S, Swerdlow SH, Yoshino T.
    • Journal Title

      Am J Surg Pathol

      Volume: - Pages: 946-955

    • DOI

      10.1097/pas.0000000000000206

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Clinicopathological features and EGFR gene mutation status in elderly patients with resected non-small-cell lung cancer.2014

    • Author(s)
      Nishii T, Yokose T, Miyagi Y, Daigo Y, Ito H, Isaka T, Imai K, Murakami S, Kondo T, Saito H, Oshita F, Yamada K, Matsukuma S, Tsuboi M, Nakayama H, Masuda M
    • Journal Title

      BMC Cancer

      Volume: 14 Pages: 610-610

    • DOI

      10.1186/1471-2407-14-610

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Identification of a nuclear protein, LRRC42, involved in lung carcinogenesis2014

    • Author(s)
      T. Fujitomo, Y. Daigo, K. Matsuda, K. Ueda, and Y. Nakamura
    • Journal Title

      International Journal of Oncology

      Volume: 45(1) Pages: 147-156

    • DOI

      10.3892/ijo.2014.2418

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Identification of immunogenic LY6K long peptide encompassing both CD4+ and CD8+ T-cell epitopes and eliciting CD4+ T-cell immunity in patients with malignant desease2014

    • Author(s)
      Tomita, Y.*, Yuno, A.*, Tsukamoto, H., Senju, S., Kuroda, Y., Hirayama, M., Imamura, Y., Yatsuda, J., Sayem, M. A., Irie, A., Hamada A., Jono, H., Yoshida, K., Tsunoda, T, Daigo, Y., Kohrogi, H., Yoshitake, Y., Nakamura,Y., Shinohara, M., Nishimura, Y.
    • Journal Title

      Oncoimmunology

      Volume: 3

    • DOI

      10.4161/onci.28100

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Cell division cycle-associated protein 1 overexpression is essential for the malignant potential of colorectal cancers.2014

    • Author(s)
      Kobayashi Y, Takano A, Miyagi Y, Tsuchiya E, Sonoda H, Shimizu T, Okabe H, Tani T, Fujiyama Y, Daigo Y.
    • Journal Title

      Int J Oncol

      Volume: 44 Pages: 69-77

    • DOI

      10.3892/ijo.2013.2177

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Proteomic analysis of proteins related to prognosis of lung adenocarcinoma.2014

    • Author(s)
      Okayama A, Miyagi Y, Oshita F, Nishi M, Nakamura Y, Nagashima Y, Akimoto K, Ryo A, Hirano H.
    • Journal Title

      J Proteome Res

      Volume: 13 Issue: 11 Pages: 4686-464

    • DOI

      10.1021/pr4012969

    • NAID

      130005454677

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] SIRT1 expression is associated with a poor prognosis, whereas DBC1 is associated with favorable outcomes in gastric cancer.2014

    • Author(s)
      Noguchi A, Kikuchi K, Zheng H, Takahashi H, Miyagi Y, Aoki I, Takano Y.
    • Journal Title

      Cancer Med

      Volume: 3 Issue: 6 Pages: 1553-61

    • DOI

      10.1002/cam4.310

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Angiomodulin (AGM/IGFBP-rP1) is a molecular marker of vascular endothelial cells activated by VEGF in human breast cancers.2014

    • Author(s)
      Komiya, E, Sato, H., Ise, I., Watanabe, N., Higashi, H., Miyagi, Y., Miyazaki, K.
    • Journal Title

      Cancer Med.

      Volume: 印刷中 Issue: 3 Pages: 537-549

    • DOI

      10.1002/cam4.216

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Lung adenocarcinoma subtypes definable by lung development-related miRNA expression profiles in association with clinicopathologic features2014

    • Author(s)
      Arima C, Kajino T, Tamada Y, Imoto S, ShimadaY, Nakatochi, M, Suzuki M, Isomura H, Yatabe Y, Yamaguchi T, Yanagisawa K, Miyano S, Takahashi T
    • Journal Title

      Carcinogenesis

      Volume: 35 Pages: 2224-2231

    • DOI

      10.1093/carcin/bgu127

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Expression of chromobox homolog 7 (CBX7) is associated with poor prognosis in ovarian clear cell adenocarcinoma via TRAIL-induced apoptotic pathway regulation2014

    • Author(s)
      Shinjo K, Yamashita Y, Yamamoto E, Akatsuka S, Uno N, Kamiya A, Niimi K, Sakaguchi Y, Nagasaka T, Takahashi T, Shibata K, Kajiyama H, Kikkawa F, Toyokuni S
    • Journal Title

      Int J Cancer.

      Volume: 135 Pages: 308-18

    • DOI

      10.1002/ijc.28692

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Tumor-derived Interleukin-1 promotes lymphangiogenesis and lymph node metastasis through M2-type macrophages2014

    • Author(s)
      Watari K, Shibata T, Kawahara A, Sata K, Nabeshima H, Shinoda A, Abe H, Azuma K, Murakami Y, Izumi, H, Takahashi T, Kage M, Kuwano M, Ono M.
    • Journal Title

      PLoS One

      Volume: 9

    • DOI

      10.1371/journal.pone.0099568

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Cancer-promoting role of adipocytes in asbestos-induced mesothelial carcinogenesis through dysregulated adipocytokine production2014

    • Author(s)
      S. H. Chew, Y. Okazaki, H. Nagai, N. Misawa, S. Akatsuka, K. Yamashita, L. Jiang, Y. Yamashita, M. Noguchi, K. Hosoda, Y. Sekido, T. Takahashi, S. Toyokuni
    • Journal Title

      Cancer-promoting role of adipocytes in asbestos-induced mesothelial carcinogenesis through dysregulated adipocytokine production

      Volume: 35(1) Pages: 164-172

    • DOI

      10.1093/carcin/bgt267

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Multimodal Effects of Small Molecule ROCK and LIMK Inhibitors on Mitosis, and Their Implication as Anti-Leukemia Agents.,2014

    • Author(s)
      Oku Y, Tareyanagi C, Takaya S, Osaka S, Ujiie H, Yoshida K, Nishiya N, Uehara Y.
    • Journal Title

      PLoS One

      Volume: 9

    • DOI

      10.1371/journal.pone.0092402

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A zebrafish chemical suppressor screening identifies small molecule inhibitors of the Wnt/β-catenin pathway.2014

    • Author(s)
      Nishiya N, Oku Y, Kumagai Y, Sato Y, Yamaguchi E, Sasaki A, Shoji M, Ohnishi Y, Okamoto H, Uehara Y.
    • Journal Title

      Chemistry & Biology

      Volume: 21 Pages: 530-540

    • DOI

      10.1016/j.chembiol.2014.02.015

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Total Synthesis of Burkholdacs A and B and 5,6,20-Tri-epi-burkholdac A: HDAC Inhibition and Antiproliferative Activity2014

    • Author(s)
      Yurie Fukui, Koichi Narita, Singo Dan, Takao Yamori, Akihiro Ito, Minoru Yoshida, Tadashi Katoh
    • Journal Title

      Eur. J. Med. Chem.

      Volume: 76 Pages: 301-313

    • DOI

      10.1016/j.ejmech.2014.02.044

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 5-Lipoxygenase and CysLT1 regulate EGF‐induced cell migration through Tiam1 upregulation and Rac1 activation.2014

    • Author(s)
      Magi S, Takemoto Y, Kobayashi H, Kasamatsu M, Akita T, Tanaka A, Takano K, Tashiro E, Igarashi Y, Imoto M.
    • Journal Title

      Cancer Sci

      Volume: 105 Pages: 290-296

    • DOI

      10.1111/cas.12340

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] TRIB1 supports prostate tumorigenesis and tumor-propagating cell survival by regulation of endoplasmic reticulum chaperone expression2014

    • Author(s)
      Mashima T, Soma-Nagae T, Migita T, Kinoshita R, Iwamoto A, Yuasa T, Yonese J, Ishikawa Y, Seimiya H
    • Journal Title

      Cancer Research

      Volume: 74 Pages: 4888-4897

    • DOI

      10.1158/0008-5472.can-13-3718

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Inhibition of ATP citrate lyase induces triglyceride accumulation with altered fatty acid composition in cancer cells.2014

    • Author(s)
      5.Migita T, Okabe S, Ikeda K, Igarashi S, Sugawara S, Tomida A, Soga T, Taguchi R, Seimiya H.
    • Journal Title

      Int J Cancer

      Volume: 135 Pages: 37-47

    • DOI

      10.1002/ijc.28652

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Xanthohumol suppresses oestrogen-signalling in breast cancer through the specific inhibition of BIG3-PHB2 interaction.2014

    • Author(s)
      Yoshimaru T, Komatsu M, Tashiro E, Imoto M, Osada H, Miyoshi M, Honda J, Sasa M, and Katagiri T
    • Journal Title

      Sci Rep

      Volume: 4 Pages: 7335-7335

    • DOI

      10.1038/srep07355

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] A small compound targeting TACC3 revealed its spatiotemporally different contributions to the spindle assembly in cancer cells2014

    • Author(s)
      Yao R, Kondoh Y, Natsume Y, Yamanaka H, Inoue M, Toki H, Takagi R, Shimizu T, Yamori T, Osada H, Noda T
    • Journal Title

      Oncogene

      Volume: in press Issue: 33 Pages: 1-11

    • DOI

      10.1038/onc.2013.382

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Regulation of TFPI-2 (Tissue Factor Pathway Inhibitor 2) expression by Lysine-Specific Demethylase 1 and 2 (LSD1 and LSD2).2014

    • Author(s)
      2.Mino, K., Nishimura, S., Ninomiya, S., Tujii, H., Matsumori, Y., Tsuchida, M., Hosoi, M., Koseki, K., Wada, S., Hasegawa, M., Sasaki, R., Murakami-Yamaguchi, Y., Narita, H., Suzuki, T., Miyata, N., Mizukami, T.
    • Journal Title

      Biosci Biotechnol Biochem

      Volume: 78 Issue: 6 Pages: 1010-1017

    • DOI

      10.1080/09168451.2014.910104

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Array-based genome-wide RNAi screening to identify shRNAs that enhance p53-related apoptosis in human cancer cells2014

    • Author(s)
      Idogawa M, Ohashi T, Sugisaka J, Sasaki Y, Suzuki H, Tokino T
    • Journal Title

      Oncotarget

      Volume: 5 Issue: 17

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Forkhead transcription factor FOXF1 is a novel target gene of the p53 family and regulates cancer cell migration and invasiveness2014

    • Author(s)
      Tamura M, Sasaki Y, Koyama R, Takeda K, Idogawa M, Tokino T
    • Journal Title

      Oncogene

      Volume: (in press) Issue: 40 Pages: 4837-46

    • DOI

      10.1038/onc.2013.427

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Identification and analysis of large intergenic non-coding RNAs regulated by p53 family members through a genome-wide analysis of p53-binding sites2014

    • Author(s)
      Idogawa M, Ohashi T, Sasaki Y, Maruyama R, Kashima L, Suzuki H, Tokino T
    • Journal Title

      Human Molecular Genetics

      Volume: 23 Issue: 11 Pages: 2847-2857

    • DOI

      10.1093/hmg/ddt673

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Silencing of microRNA-122 is an early event during hepatocarcinogenesis from non-alcoholic steatohepatitis.2014

    • Author(s)
      Takaki Y, Saito Y, Takasugi A, Toshimitsu K, Yamada S, Muramatsu T, Kimura M, Sugiyama K, Suzuki H, Arai E, Ojima H, Kanai Y, Saito H.
    • Journal Title

      Cancer Science

      Volume: 105 Pages: 1254-1260

    • DOI

      10.1111/cas.12498

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Low serum level of high-sensitivity C-reactive protein in a Japanese subject with MODY3.2014

    • Author(s)
      Ohki T, Utsu Y, Morita S, Karim M.F., Sato Y, Yoshizawa T, Yamamura K, Yamada K, Kasayama S, Yamagata K.
    • Journal Title

      J. Diabetes Invest.

      Volume: in press.

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Autophagy regulation in the pancreatic acinar cells is independent of epidermal growth factor receptor signaling.2014

    • Author(s)
      Ozaki, N., Fukuchi, Y., Tomiyoshi, S., Uehara1, H., Ida, S., Wang, J., Kimi Araki, K., Sibilia, M., Baba, H., and Yamamura, K., and Ohmuraya, M.
    • Journal Title

      Biochem. Biophysic. Res. Comm.

      Volume: in press.

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] mTORC1 controls the cell cycle of the earliest T-lineage-committed cells and its inactivation eradicates acute lymphoblastic T-cell leukemia in mice.2014

    • Author(s)
      Hoshii, T., Kasada, A., Hatakeyama, N., Ohtani,M., Tadokoro, Y., Naka, K., Ikenoue, T., Ikawa, T., Kawamoto, H., Araki, K., Yamamura, K., Matsuda, S. and Hirao, A.
    • Journal Title

      Proc. Natl. Acad. Sci. USA.

      Volume: in press.

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rescue In Vitro Fertilization Method for Legacy Stock of Frozen Mouse Sperm.2014

    • Author(s)
      Nakagata, N., Takeo, T., Fukumoto, K., Haruguchi, Y., Kondo, T., Takeshita, Y., Nakamuta, Y., Umeno, T. and Tsuchiyama, S.
    • Journal Title

      J Reprod Dev

      Volume: 60 Pages: 167-170

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preclinical evaluation of an O(6)-methylguanine-DNA methyltransferase-siRNA/liposome complex administered by convection-enhanced delivery to rat and porcine brains.2014

    • Author(s)
      Tsujiuchi T., Natsume A., Motomura K., Kondo G., Ranjit M., Hachisu R., Sugimura I., Tomita S., Takehara I., Woolley M., Barua N.U., Gill S.S., Bienemann A.S., Yamashita Y., Toyokuni S., Wakabayashi T.
    • Journal Title

      Am J Transl Res. eCollection 2014

      Volume: 6 Pages: 169-78

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Novel Transgenic Mouse Model Carrying Human Tribbles Related Protein 3 (TRB3) Gene and Its Site Specific Phenotype.2014

    • Author(s)
      Y. Sakai, K. Fukamachi, M. Futakuchi, I. Miyoshi, H. Tsuda, M. Suzui, H. Hayashi.
    • Journal Title

      Biol. Pharm. Bull.

      Volume: in press.

    • NAID

      130004147355

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Importance of the progesterone receptor (PR) and the epidermal growth factor receptor (EGFR), but not the estrogen receptor (ER), for chemically induced lung carcinogenesis in female A/J mice.2014

    • Author(s)
      Kishi S., Yokohira M., Yamakawa K., Saoo K., Imaida K.
    • Journal Title

      Oncol. Lett.

      Volume: in press

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cross-boundary Cancer Studies at the University of Tokyo: View from the world of science and reason.2014

    • Author(s)
      Akaza H.
    • Journal Title

      Japanese journal of clinical oncology

      Volume: 44 Suppl 1

    • DOI

      10.1093/jjco/hyt228

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cross-boundary cancer studies at the University of Tokyo: Surviving cancer in Asia: introduction.2014

    • Author(s)
      Akaza H, Kawahara N.
    • Journal Title

      Japanese journal of clinical oncology

      Volume: 44 Suppl 1

    • DOI

      10.1093/jjco/hyt231

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Japanese Cancer Association Meeting UICC International session--what is cost-effectiveness in cancer treatment?2014

    • Author(s)
      Akaza H, Kawahara N, Roh JK et al.
    • Journal Title

      Asian Pacific journal of cancer prevention : APJCP

      Volume: 15 Pages: 3-10

    • DOI

      10.7314/apjcp.2014.15.1.3

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Associations of dietary patterns with metabolic syndrome and insulin resistance: a cross-sectional study in a Japanese population.2014

    • Author(s)
      Arisawa K, Uemura H, Yamaguchi M et al.
    • Journal Title

      J Med Invest

      Volume: in press

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Associations between hOGG1 Ser326Cys polymorphism and increased body mass index and fasting glucose in the Japanese general population.2014

    • Author(s)
      Hara M, Nakamura K, Nanri H, KIta Y, Suzuki S, Ohnaka K, Mikami H, Kubo M, Tanaka H et al.
    • Journal Title

      Journal of epidemiology / Japan Epidemiological Association

      Volume: in press

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comparison of plasma levels of nutrients-related biomarkers among Japanese populations in Tokyo, Japan, in Sao Paulo, Brazil, and in Hawaii, USA.2014

    • Author(s)
      Iwasaki M, Franke A, Hamada G, Tsugane S et al.
    • Journal Title

      European Journal of Cancer Prevention

      Volume: in press

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] C-ERC/mesothelin provokes lymphatic invasion of colorectal adenocarcinoma2014

    • Author(s)
      Kawamata F, Homma S, Kamachi H, Einama T, Kato Y, Tsuda M, Tanaka S, Maeda M, Kajino K, Hino O, Takahashi N, Kamiyama T, Nishihara H, Taketomi A, Todo S
    • Journal Title

      Journal of gastroenterology

      Volume: 49 Pages: 81-92

    • DOI

      10.1007/s00535-013-0773-6

    • NAID

      120005537455

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ABCG2 dysfunction causes hyperuricemia due to both renal urate underexcretion and renal urate overload2014

    • Author(s)
      Matsuo, H. Nakayama, A. Sakiyama, M. et al.
    • Journal Title

      Sci Rep.

      Volume: 4:3755 Pages: 3755-3755

    • DOI

      10.1038/srep03755

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Plasma amino acid profiles are associated with biomarkers of breast cancer risk in premenopausal Japanese women.2014

    • Author(s)
      Nagata C, Wada K, Tsuji M et al.
    • Journal Title

      Cancer causes & control : CCC

      Volume: 25 Pages: 143-149

    • DOI

      10.1007/s10552-013-0316-8

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Inverse correlation between serum interleukin-6 and iron levels among Japanese adults: a cross-sectional study.2014

    • Author(s)
      Nakagawa H, Tamura T, Mitsuda Y, Wakai K et al.
    • Journal Title

      BMC hematology

      Volume: 14 Pages: 6-6

    • DOI

      10.1186/2052-1839-14-6

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Biomarkers for predicting the efficacy of anti-epidermal growth factor receptor antibody in the treatment of colorectal cancer2014

    • Author(s)
      Okada Y, Miyamoto H, Goji T, Takayama T.
    • Journal Title

      Digestion

      Volume: 89 Pages: 18-23

    • DOI

      10.1159/000356202

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] IGKC and FcgammaR genotypes and humoral immunity to HER2 in breast cancer.2014

    • Author(s)
      Pandey JP, Kistner-Griffin E, Black L, Tsugane S et al.
    • Journal Title

      Immunobiology

      Volume: 219 Pages: 113-117

    • DOI

      10.1016/j.imbio.2013.08.005

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A common variant of leucine-rich repeat-containing 16A (LRRC16A) gene is associated with gout susceptibility2014

    • Author(s)
      Sakiyama, M. Matsuo, H. Shimizu, S. Chiba, T. Nakayama, A. Takada, Y. Nakamura, T. Takada, T. Morita, E. Naito, M. Wakai, K. Inoue, H. Tatsukawa, S. Sato, J. Shimono, K. Makino, T. Satoh, T. Suzuki, H. Kanai, Y. Hamajima, N. Sakurai, Y. Ichida, K. Shimizu, T. Shinomiya, N.
    • Journal Title

      Human cell

      Volume: 27(1) Pages: 1-4

    • DOI

      10.1007/s13577-013-0081-8

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High antitumor activity of pladienolide B and its derivative in gastric cancer.2014

    • Author(s)
      Sato M, Muguruma N, Nakagawa T, Takayama T et al.
    • Journal Title

      Cancer science

      Volume: 105 Pages: 110-116

    • DOI

      10.1111/cas.12317

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A novel somatic FGFR3 mutation in primary lung cancer2014

    • Author(s)
      Shinmura K, Sugimura H et al.
    • Journal Title

      Oncology reports

      Volume: 31(3) Pages: 1219-1224

    • DOI

      10.3892/or.2014.2984

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] TNK2 gene amplification is a novel predictor of a poor prognosis in patients with gastric cancer2014

    • Author(s)
      Shinmura K, Sugimura H et al.
    • Journal Title

      Journal of surgical oncology

      Volume: 109(3) Pages: 189-197

    • DOI

      10.1002/jso.23482

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Counts of Slackia sp. strain NATTS in intestinal flora are correlated to serum concentrations of equol both in prostate cancer cases and controls in Japanese men.2014

    • Author(s)
      Sugiyama Y, Nagata Y, Fukuta F, Masumori N, Akaza H et al.
    • Journal Title

      J Cancer Prev

      Volume: in press

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Breakages at YWHAE, FAM22A, and FAM22B loci in uterine angiosarcoma : a case report with immunohistochemical and genetic analysis2014

    • Author(s)
      Suzuki S, Sugimura H et al.
    • Journal Title

      Pathology, research and practice

      Volume: 210(2) Pages: 130-134

    • DOI

      10.1016/j.prp.2013.09.009