Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas

• Project Area: がん研究分野の特性等を踏まえた支援活動
• Project/Area Number: 221S0001
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Research Institution: The University of Tokyo
• Principal Investigator: IMAI Kohzoh (2012-2015) 東京大学, 医科学研究所, 特任研究員 (60117603); 中村 祐輔 (2010-2011) 東京大学, 医科学研究所, 教授 (70217909)
• Co-Investigator(Kenkyū-buntansha): INOUE Junichiro 東京大学, 医科学研究所, 教授 (70176428) ; NAKAMURA Takuro 公益財団法人がん研究会, がん研究所, 副所長 (00180373) ; ISHIKAWA Fuyuki 京都大学, 大学院生命科学研究科, 教授 (30184493) ; YAMAMURA Kenichi 熊本大学, 生命資源研究・支援センター, シニア教授 (90115197) ; ARAKI Kimi 熊本大学, 生命資源研究・支援センター, 教授 (90211705) ; YAO Ryouji 公益財団法人がん研究会, がん研究所 細胞生物部, 主任研究員 (80291095) ; TAKANO Hiroshi 公益財団法人がん研究会, がん研究所 細胞生物部, 特任研究員 (00241555) ; TAKAKURA Akira 公益財団法人実験動物中央研究所, ICLASモニタリングセンター, 事業部門長 (60167484) ; KATOH Hideki 浜松医科大学, 医学部附属動物実験施設, 准教授 (30142053) ; NAKAGATA Naomi 熊本大学, 生命資源研究支援センター, 教授 (30159058) ; TOYOKUNI Shinya 名古屋大学, 大学院医学系研究科, 教授 (90252460) ; WANIBUCHI Hideki 大阪市立大学, 大学院医学研究科, 教授 (90220970) ; OGAWA Katsuhiro 旭川医科大学, 医学部, 名誉教授 (50045514) ; MITSUMORI Kunitoshi 東京農工大学, 農学研究院, 教授 (10239296) ; YAMADA Yasuhiro 京都大学, iPS細胞研究所, 教授 (70313872) ; SHIBUTANI Makoto 東京農工大学, 大学院農学研究院, 教授 (20311392) ; IMAIDA Katsumi 香川大学, 医学部, 教授 (90160043) ; FUTAKUCHI Mitsuru 名古屋市立大学, 大学院医学研究科, 准教授 (60275120) ; KANDA Hiroaki 公益財団法人がん研究会, がん研究所 病理部, 主任研究員 (90260067) ; TANAKA Hideo 愛知県がんセンター研究所, 疫学・予防部, 部長 (60470168) ; WAKAI Kenji 名古屋大学, 大学院医学系研究科, 教授 (50270989) ; MIKAMI Haruo 千葉県がんセンター(研究所), がん予防センター, 部長 (10332355) ; SUZUKI Sadao 名古屋市立大学, 大学院医学研究科, 教授 (20226509) ; MIURA Katsuyuki 滋賀医科大学, 医学部, 教授 (90257452) ; WATANABE Yoshiyuki 京都府立医科大学, 大学院医学研究科, 教授 (00191809) ; ARISAWA Kokichi 徳島大学, 大学院医歯薬学研究部, 教授 (30203384) ; TANAKA Keitaro 佐賀大学, 医学部, 教授 (50217022) ; TAKEZAKI Toshiro 鹿児島大学, 大学院医歯学総合研究科, 教授 (50227013) ; FURUSHO Norihiro 九州大学, 大学院医学研究院, 准教授 (10346786) ; NAITO Mariko 名古屋大学, 大学院医学系研究科, 准教授 (10378010) ; OHNAKA Keizo 九州大学, 医学研究院, 講師 (30325518) ; KITA Yoshikuni 敦賀市立看護大学, 看護学部, 准教授 (30147524) ; KURIKI Kiyonori 静岡県立大学, 食品栄養科学部, 准教授 (20543705) ; TAMAKAOSHI Akiko 北海道大学, 大学院医学研究科, 教授 (90236737) ; EGUCHI Hidetaka 埼玉医科大学, 医学部, 准教授 (00260232) ; KUBO Michiaki 国立研究開発法人理化学研究所, 統合生命医科学研究センター, 副センター長 (30442958) ; HAMAJIMA Nobuyuki 名古屋大学, 大学院医学系研究科, 教授 (30172969) ; NAGATA Chisato 岐阜大学, 大学院医学系研究科, 教授 (30283295) ; HINO Okio 順天堂大学, 医学部, 教授 (90127910) ; TAHARA Hidetoshi 広島大学, 大学院医歯薬保健学研究院, 教授 (00271065) ; SUGIMURA Haruhiko 浜松医科大学, 医学部, 教授 (00196742) ; TSUGANE Shoichiro 国立研究開発法人国立がん研究センター, がん予防・検診研究センター, センター長 (40179982) ; NAKATOCHI Masahiro 名古屋大学, 医学部附属病院, 病院助教 (10559983) ; TAKAYAMA Tetsuji 徳島大学, 大学院医歯薬学研究部, 教授 (10284994) ; AKAZA Hideyuki 東京大学, 情報学環, 特任教授 (70010486) ; TAKAHASHI Satoru 日本大学, 医学部, 教授 (50197141) ; TSUKAMOTO Taiji 札幌医科大学, 医学部, 教授 (50112454) ; NAITO Seiji 九州大学, 大学院医学研究院, 教授 (40164107) ; MASUMORI Naoya 札幌医科大学, 医学部, 教授 (20295356) ; YOKOMIZO Akira 九州大学, 大学院医学研究院, 准教授 (60346781) ; NAMIKI Mikio 金沢大学, 医学系, 教授 (70155985) ; FUJIMOTO Kiyohide 奈良県立医科大学, 医学部, 教授 (50264867) ; FUJIOKA Tomoaki 岩手医科大学, 医学部, 教授 (80173409) ; HORIE Shigeo 順天堂大学, 大学院医学系研究科, 教授 (40190243) ; MORI Mitsuru 札幌医科大学, 医学部, 教授 (50175634) ; MORIWAKI Hisataka 岐阜大学, 大学院医学系研究科, 教授 (50174470) ; Shimizu Masahito 岐阜大学, 大学院医学系研究科, 教授 (90402198) ; KANNAGI Mari 東京医科歯科大学, 大学院医歯学総合研究科, 教授 (80202034) ; ISHIDA Takashi 名古屋市立大学, 大学院医学研究科, 准教授 (80405183) ; MATSUOKA Masao 京都大学, ウイルス研究所, 教授 (10244138) ; YAMAOKA Shoji 東京医科歯科大学, 大学院医歯学総合研究科, 教授 (90263160) ; TANAKA Yuetsu 琉球大学, 大学院医学研究科, 教授 (30163588) ; WATANABE Toshiki 東京大学, 大学院新領域創成科学研究科, 教授 (30182934) ; YASUI Hiroshi 東京大学, 医科学研究所, 特任准教授 (40448593) ; TSUCHIYA Eiju 湯沢町保健医療センター, 特任研究員 (00072314) ; DAIGO Yataro 東京大学, 医科学研究所, 特任教授 (30345029) ; MIYAGI Yohei 地方独立行政法人神奈川県立病院機構, 神奈川県立がんセンター・臨床研究所, 総括部長 (00254194) ; TAKAHASHI Takashi 名古屋大学, 大学院医学系研究科, 教授 (50231395) ; YAMORI Takao 公益財団法人がん研究会, がん化学療法センター, 部長 (60200854) ; SEIMIYA Hiroyuki 公益財団法人がん研究会, がん化学療法センター分子生物治療研究部, 部長 (50280623) ; UEHARA Yoshimasa 岩手医科大学, 薬学部, 教授 (50160213) ; YOSHIDA Minoru 国立研究開発法人理化学研究所, 吉田化学遺伝学研究室, 主任研究員 (80191617) ; IMOTO Masaya 慶應義塾大学, 理工学部, 教授 (60213253) ; FUKAZAWA Hidesuke 国立感染症研究所, 真菌部, 室長 (10218878) ; KAKEYA Hideaki 京都大学, 大学院薬学研究科, 教授 (00270596) ; DAN Shingo 公益財団法人がん研究会, がん化学療法センター分子薬理部, 副部長 (70332202) ; TOMIDA Akihiro 公益財団法人がん研究会, がん化学療法センター, 部長 (40251483) ; KAWADA Manabu 公益財団法人微生物化学研究会, 微生物化学研究所沼津支所, 支所長 (20300808) ; OSADA Hiroyuki 国立研究開発法人理化学研究所, 環境資源科学研究センター, 副センター長 (80160836) ; MATSUURA Masaaki 帝京大学, 大学院公衆衛生学研究科, 教授 (40173794) ; MIZUKAMI Tamio 長浜バイオ大学, バイオサイエンス学部, 教授 (80367896) ; MASHIMA Tetsuo 公益財団法人がん研究会, がん化学療法センター分子生物治療研究部, 主任研究員 (30311228) ; USHIJIMA Masaru 公益財団法人がん研究会, ゲノムセンター, 研究員 (60328565) ; TOKINO Takashi 札幌医科大学, 医学部, 教授 (40202197) ; SUZUKI Hiromu 札幌医科大学, 医学部, 教授 (20381254) ; SHINOMURA Yasuhisa 札幌医科大学, 医学部, 教授 (90162619) ; NOSHO Katsuhiko 札幌医科大学, 医学部, 講師 (10597339)
• Co-Investigator(Renkei-kenkyūsha): MIYAZONO Kohei 東京大学, 医学系研究科, 教授 (90209908) ; INAZAWA Johji 東京医科歯科大学, 難治疾患研究所, 教授 (30193551) ; HIROTA Toru 公益財団法人がん研究会, がん研究所 実験病理部, 部長 (50421368) ; NODA Tetsuo 公益財団法人がん研究会, がん研究所, 所長 (10183550) ; SUZUKI Misao 熊本大学, 生命資源研究・支援センター, 准教授 (60253720) ; TAKEDA Naoki 熊本大学, 生命資源研究・支援センター, 助教 (90304998) ; YAGINUMA Katsuyuki 公益財団法人がん研究会, がん研究所 細胞生物部, 研究員 (40182307) ; SUGITANI Yoshinobu 公益財団法人がん研究会, がん研究所 細胞生物部, 研究員 (80360569) ; ITO Hidemi 愛知県がんセンター研究所, 疫学・予防部, 室長 (90393123) ; HOSONO Satoyo 愛知県がんセンター研究所, 疫学・予防部, 主任研究員 (80402600) ; IWASAKI Motoki 独立行政法人国立がん研究センター, がん予防・検診研究センター, 室長 (60392338) ; NAGASE Hiroki 千葉県がんセンター研究所, がん遺伝創薬研究室, 研究所長 (90322073) ; NISHITA Hiroki 札幌医科大学, 医学部, 特任助教 (40531257) ; KONO Suminori 九州大学, 大学院医学研究院, 教授 (70128015) ; HASHIMOTO Syuji 藤田保健衛生大学, 医学部衛生学講座, 教授 (50148334) ; YAMAGUCHI Kazunari 熊本大学, 発生医学研究所, 特別研究員 (20128325) ; TAKANO Atsushi 東京大学, 医科学研究所, 特任講師 (50582607) ; TERAMOTO Koji 滋賀医科大学, 医学部, 特任講師 (10452244) ; MATSUDA Koichi 東京大学, 大学院新領域創成科学研究科, 教授 (90401257) ; TANAKA Yukichi 神奈川県立こども医療センター, 臨床研究所, 所長 (50420691) ; AOKI Ichiro 横浜市立大学, 大学院医学研究科, 教授 (00184028) ; OSAMURA Yoshiyuki 国際福祉大学三田病院, 病理診断センター, センター長 (10100992) ; NAKAMURA Naoya 東海大学, 医学部, 教授 (50227922) ; SUZUKI Noboru 聖マリアンナ医科大学, 医学部, 教授 (40235982) ; TAJIRI Michihiko 神奈川県立循環器呼吸器病センター, 呼吸器外科, 部長 (00449117) ; KAWASAKI Takashi 新潟県立がんセンター新潟病院, 病理部, 部長 (20377188) ; YOKOSE Tomoyuki 神奈川県立がんセンター, 病理診断科, 部長 (10221665) ; YANAGISAWA Kiyoshi 名古屋大学, 大学院医学系研究科, 講師 (20372112) ; HIRAKAWA Akihiro 名古屋大学, 医学部附属病院先端医療・臨床研究支援センター, 講師 (90609330) ; IIJIMA Yoshihiko 名古屋大学, 大学院医学系研究科, 特任准教授 (50584679) ; ZEMBUTSU Hitoshi 東京大学, 医科学研究所, 助教 (90372820) ; SASAKI Yasushi 札幌医科大学, 医学部フロンティア医学研究所, 准教授 (70322328) ; IDOGAWA Masashi 札幌医科大学, 医学部フロンティア医学研究所, 講師 (00404749) ; MARUYAMA Reo 札幌医科大学, 医学部分子生物学講座, 准教授 (60607985) ; KAI Masahiro 札幌医科大学, 医学部分子生物学講座, 講師 (80260777)
• Project Period (FY): 2010-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Keywords: 若手支援 / 国際研究者交流 / 遺伝子改変マウス / 病理形態学 / ゲノムコーホート研究 / 次世代分子解析技術 / アカデミア創薬 / ゲノム・エピゲノム解析支援 / 個別化がん予防 / 国際交流 / ATL発症予防 / 分子疫学コーホート研究 / がん化学予防 / ATL発がん機序 / ATL発症リスク / がん分子標的薬剤

Outline of Final Research Achievements

We started this project first supporting scientists who aim to overcome cancer, and from 2014 we extended our support to scientists in life sciences. The outcome has been as follows: General Support Group fostered young scientists and those who will be involved in research support in the future, and developed international academic exchanges. Our support services such as providing genetically modified mice and providing bioresources including cancer tissues enabled many scientists to conduct international and cutting-edge researches. All Japan Cohort Group and ATL Study Group (originated in Japan) collected more than 110,000 important samples and contributed for many scientists to produce their results. Chemotherapy Group and Genome and Epigenome Group also achieved more than their original goals. Further, we organized open lectures for general public to inform the importance of scientific support.

Research Products

• [Int'l Joint Research] ハルビン医科大学/南京大学 (中国)
  • Country Name: 中国
  • Counterpart Institution: ハルビン医科大学/南京大学
• [Int'l Joint Research] Tufts大学/Medical University of South Carolina/University of Hawaii Cancer Center(アメリカ)
  • Country Name: アメリカ
  • Counterpart Institution: Tufts大学/Medical University of South Carolina/University of Hawaii Cancer Center
• [Int'l Joint Research] University of Medicine and Pharmacy(ルーマニア)
  • Country Name: ルーマニア
  • Counterpart Institution: University of Medicine and Pharmacy
• [Int'l Joint Research] Maria Sklodowska-Curie Memorial Cancer C(ポーランド)
  • Country Name: ポーランド
  • Counterpart Institution: Maria Sklodowska-Curie Memorial Cancer C
• [Int'l Joint Research] University of Alberta(カナダ)
  • Country Name: カナダ
  • Counterpart Institution: University of Alberta
• [Int'l Joint Research]
  • # of Other Countries: 1
• [Journal Article] Report of the Japan diabetes society/Japanese cancer association joint committee on diabetes and cancer, Second report. (2016)
  • Author(s): Goto A, Noto H, Noda M, Ueki K, Kasuga M, Tajima N, Ohashi K, Sakai R, Tsugane S, Hamajima N, Tajima K, Imai K, Nakagama H.
  • Journal Title: Cancer Science Volume: 107(3) Pages: 369-71
  • DOI: 10.1111/cas.12889.
  • Peer Reviewed / Open Access
• [Journal Article] Report of the Japan Diabetes Society (JDS)/Japanese Cancer Association (JCA) Joint Committee on Diabetes and Cancer, Second Report (2016)
  • Author(s): Goto A, Noto H, Noda M, Ueki K, Kasuga M, Tajima N, Ohashi K, Sakai R, Tsugane S, Hamajima N, Tajima K, Imai K, Nakagama H.
  • Journal Title: Diabeto Int. Volume: 7 Pages: 12-15
  • DOI: 10.1007/s13340-016-0257-z
  • Peer Reviewed
• [Journal Article] Association of Fusobacterium nucleatum with immunity and molecular alterations in colorectal cancer. (2016)
  • Author(s): Nosho K, Sukawa Y, Adachi Y, Ito M, Mitsuhashi K, Kurihara H, Kanno S, Yamamoto I, Ishigami K, Igarashi H, Maruyama R, Imai K, Yamamoto H, Shinomura Y.
  • Journal Title: World J Gastroenterol. Volume: 22 Pages: 557-66
  • DOI: 10.3748/wjg.v22.i2.557
  • Peer Reviewed
• [Journal Article] The relationship between EZH2 expression and microRNA-31 in colorectal cancer and the role in evolution of the serrated pathway. (2016)
  • Author(s): Kurihara H, Maruyama R, Ishiguro K, Kanno S, Yamamoto I, Ishigami K, Mitsuhashi K, Igarashi H, Ito M, Tanuma T, Sukawa Y, Okita K, Hasegawa T, Imai K, Yamamoto H, Shinomura Y, Nosho K.
  • Journal Title: Oncotarget Volume: in press Pages: -
  • DOI: 10.18632/oncotarget.7260
  • Peer Reviewed
• [Journal Article] Transgenic mouse model for imaging of interleukin-1β-related inflammation in vivo (2016)
  • Author(s): Iwawaki, T., Akai, R., Oikawa, D., Toyoshima, T., Yoshino, M., Suzuki, M., Takeda, N., Ishikawa, T., Kataoka, Y. and Yamamura, K..
  • Journal Title: Sci. Reports Volume: 5 Pages: 17205
  • DOI: 10.1038/srep17205.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Cathepsin D in pancreatic acinar cells is implicated in cathepsin B and L degradation, but not in autophagic activity. (2016)
  • Author(s): Mehanna, S, Suzuki, C., Shibata, M., Sunabori, T., Imanaka, T., Araki, K., Yamamura, K., Uchiyama, Y. and Ohmuraya, M.
  • Journal Title: Biochem. Biophys. Res. Commun. Volume: 469 Pages: 405-411
  • DOI: 10.1016/j.bbrc.2015.12.002.
  • Peer Reviewed
• [Journal Article] Severe ocular phenotypes in Rbp4-deficient mice in the C57BL/6 genetic background. (2016)
  • Author(s): Shen, J., Shi, D., Suzuki, T., Xia, Z., Zhang, H., Araki, K., Wakana, S., Takeda, N., Yamamura, K., Jin, S. and Li. Z.
  • Journal Title: Lab. Invest. Volume: in press Pages: in press
  • DOI: 10.1038/labinvest.2016.39.
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] GNAS and Kras cooperate to promote murine pancreatic tumorigenesis recapitulating human intraductal papillary mucinous neoplasm. (2016)
  • Author(s): Taki, K., Ohmuraya, M., Tanji, E., Komatsu, H., Hashimoto, D., Semba, K., Araki, K., Kawaguchi, Y., Baba, H. and Furukawa, T.
  • Journal Title: Oncogene Volume: in press Pages: in press
  • DOI: 10.1038/onc.2015.294.
  • Peer Reviewed
• [Journal Article] Suppression of Intestinal Tumors by Targeting the Mitotic Spindle of Intestinal Stem Cells (2016)
  • Author(s): Ryoji Yao1,*, Jun Oyanagi1, Yasuko Natsume1, Daisuke Kusama1, Yumi Kato1, Satoshi Nagayama2, Tetsuo Noda1,3
  • Journal Title: Oncogene Volume: in press Pages: in press
  • Peer Reviewed
• [Journal Article] GANP protein encoded on human chromosome 21/mouse chromosome 10 is associated with resistance to mammary tumor development. (2016)
  • Author(s): Kuwahara K, Yamamoto-Ibusuki M, Zhang Z, Phimsen S, Gondo N, Yamashita H, Takeo T, Nakagata N, Yamashita D, Fukushima Y, Yamamoto Y, Iwata H, Saya H, Kondo E, Matsuo K, Takeya M, Iwase H, Sakaguchi N.
  • Journal Title: Cancer Sci Volume: in press Pages: in press
  • DOI: 10.1111/cas.12883
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Loss of Folliculin Disrupts Hematopoietic Stem Cell Quiescence and Homeostasis Resulting in Bone Marrow Failure. (2016)
  • Author(s): Baba M, Toyama H, Sun, L, Takubo K, Suh HC, Hasumi H, Nakamura-Ishizu A, Hasumi Y, Klarmann KD, Nakagata N, Schmidt LS, Linehan WM, Suda T, Keller JR.
  • Journal Title: Stem Cells Volume: in press Pages: in press
  • DOI: 10.1002/stem.2293
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] The origin and future of oxidative stress pathology: From the recognition of carcinogenesis as an iron addiction with ferroptosis-resistance to non-thermal plasma therapy. (2016)
  • Author(s): Toyokuni S.
  • Journal Title: Pathol Int Volume: in press Pages: -
  • DOI: 10.1111/pin.12396.
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Heterogeneity of tumor cells in the bone microenvironment: Mechanisms and therapeutic targets for bone metastasis of prostate or breast cancer (2016)
  • Author(s): Futakuchi, M.*, Fukamachi, K., and Suzui, M.
  • Journal Title: Advanced Drug Delivery Reviews Volume: 99, Part B, Pages: 206-211
  • DOI: org/10.1016/j.addr.2015.11.017
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• [Journal Article] C5a inhibitor protects against ischemia/reperfusion injury in rat small intestine. (2016)
  • Author(s): Tuboly, E., Futakuchi, M*., Varga, G., Erces, D., Tokes, T., Meszaros, A., Kaszaki, J., Suzui, M., Imai, M., Okada, A., Okada, N., Boros, M., and Okada, H.
  • Journal Title: Microbiol Immunol Volume: 60 Pages: 35-46
  • DOI: 10.1111/1348-0421.12338
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  • Author(s): Fukuda, K, Uehara, Y, Nakata, E, Inoue, M, Shimazu, K, Yoshida, T, Kanda, H, Nanjo, H, Hosoi, Y, Yamakoshi, H, Iwabuchi, Y, Shibata, H A
  • Journal Title: International Journal of Radiation Biology Volume: in press Pages: -
  • DOI: 10.3109/09553002.2016.1164910.
  • Peer Reviewed
• [Journal Article] EWS-FLI1-induced osteosarcoma model unveiled a crucial role of impaired osteogenic differentiation on osteosarcoma development. (2016)
  • Author(s): Komura S, Semi K, Itakura F, Shibata H, Ohno T, Hotta A, Woltjen K, Yamamoto T, Akiyama H, Yamada Y.
  • Journal Title: Stem Cell Reports Volume: 6(4) Pages: 592-606
  • DOI: 10.1016/j.stemcr.2016.02.009.
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• [Journal Article] Aldehyde dehydrogenase 2 (ALDH2) and alcohol dehydrogenase 1B (ADH1B) polymorphisms exacerbate bladder cancer risk associated with alcohol drinking: Gene-environment interaction. (2016)
  • Author(s): Masaoka H, Ito H, Soga N, Hosono S, Oze I, Watanabe M, Tanaka H, Yokomizo A, Hayashi N, Eto M, Matsuo K.
  • Journal Title: Carcinogenesis Volume: in press Pages: -
  • DOI: 10.1093/carcin/bgw033
  • Peer Reviewed / Open Access
• [Journal Article] Development of a prediction model and estimation of cumulative risk for upper aerodigestive tract cancer on the basis of the aldehyde dehydrogenase 2 genotype and alcohol consumption in a Japanese population. (2016)
  • Author(s): Koyanagi YN, Ito H, Oze I, Hosono S, Tanaka H, Abe T, Shimizu Y, Hasegawa Y, Matsuo K.
  • Journal Title: Eur J Cancer Prev Volume: in press Pages: -
  • DOI: 10.1097/CEJ.0000000000000222
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• [Journal Article] Prognostic Value of Drinking Status and Aldehyde Dehydrogenase 2 Polymorphism in Patients With Head and Neck Squamous Cell Carcinoma. (2016)
  • Author(s): Kawakita D, Oze I, Hosono S,Ito H, Watanabe M, Yatabe Y, Hasegawa Y, Murakami S,Tanaka H, Matsuo K.
  • Journal Title: J Epidemiol Volume: ahead of print Pages: -
  • DOI: 10.2188/jea.JE20140240
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• [Journal Article] Impact of metallothionein gene polymorphisms on the risk of lung cancer in a Japanese population (2016)
  • Author(s): Nakane H, Hirano M, Ito H, Hosono S, Oze I, Matsuda F, Tanaka H, Matsuo K.
  • Journal Title: Mol Carcinog Volume: 54(S1) Pages: E122-E128
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• [Journal Article] A risk prediction model for colorectal cancer using genome-wide association study-identified polymorphisms and established risk factors among Japanese: results from two independent case-control studies (2016)
  • Author(s): Hosono, S. Ito, H. Oze, I. Watanabe, M. Komori, K. Yatabe, Y. Shimizu, Y. Tanaka, H. Matsuo, K.
  • Journal Title: Eur J Cancer Prev Volume: ahead of print Pages: -
  • DOI: 10.1097/CEJ.0000000000000213
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• [Journal Article] A variant of the CLOCK gene and related haplotypes are associated with the prevalence of type 2 diabetes in the Japanese population (2016)
  • Author(s): Uemura, H. Katsuura-Kamano, S. Yamaguchi, M. Arisawa, K. Hamajima, N. Hishida, A. Kawai, S. Oze, I. Shinchi, K. Takashima, N. Suzuki, S. Nakahata, N. Mikami, H. Ohnaka, K. Kuriyama, N. Kubo, M. Tanaka, H. Japan Multi-institutional Collaborative Cohort Study, Group
  • Journal Title: J Diabetes Volume: ahead of print Pages: -
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  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] The effects of URAT1/SLC22A12 nonfunctional variants,R90H and W258X, on serum uric acid levels and gout/hyperuricemia progression (2016)
  • Author(s): Sakiyama M, Matsuo H, Shimizu S, Nakashima H, Nakamura T, Nakayama A, Higashino T, Naito M, Suma S, Hishida A, Satoh T, Sakurai Y, Takada T, Ichida K, Ooyama H, Shimizu T, Shinomiya N
  • Journal Title: Sci Rep Volume: 6 Pages: 20148
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• [Journal Article] Adjustment of Cell-Type Composition Minimizes Systematic Bias in Blood DNA Methylation Profiles Derived by DNA Collection Protocols (2016)
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  • Journal Title: PLoS One Volume: 11 Pages: e0147519
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• [Journal Article] Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes (2016)
  • Author(s): Matsuo H, Yamamoto K, Nakaoka H, Nakayama A, Sakiyama M, Chiba T, Takahashi A, Nakamura T, Nakashima H, Takada Y, Danjoh I, Shimizu S, Abe J, Kawamura Y, Terashige S, Ogata H, Tatsukawa S, Yin G, Okada R, Morita E, Naito M, Tokumasu A, et al.
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• [Journal Article] Matrix metalloproteinase 9 gene polymorphisms are associated with a multiple family history of gastric cancer (2016)
  • Author(s): Okada R, Naito M, Hattori Y, Seiki T, Wakai K, Nanri H, Watanabe M, Suzuki S, Kairupan TS, Takashima N, Mikami H, Ohnaka K, Watanabe Y, Katsuura-Kamano S, Kubo M, Hamajima N, Tanaka H; Japan Multi-institutional Collaborative Cohort Study Group
  • Journal Title: Gastric Cancer Volume: ahead of print Pages: -
  • DOI: 10.1007/s10120-016-0608-2
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] ヘリコバクター・ピロリ感染者における慢性萎縮性胃炎の進展に及ぼす因子― 摂取栄養素分析による検討 (2016)
  • Author(s): 瀬古千佳子，松井大輔，松川泰子，小山晃英，渡邉功，尾﨑悦子，栗山長門，水野成人，渡邊 能行
  • Journal Title: 日本消化器がん検診学会雑誌 Volume: 54 Pages: 30-41
  • Peer Reviewed
• [Journal Article] ペプシノゲン法によって判定した萎縮性胃炎の背景因子の検討 (2016)
  • Author(s): 松川泰子, 瀬古千佳子, 松井大輔, 渡邉功, 小山晃英, 尾﨑悦子, 栗山長門, 水野成人, 渡邊 能行
  • Journal Title: 日本消化器がん検診学会雑誌 Volume: 54 Pages: 248-258
  • Peer Reviewed
• [Journal Article] "Influence of cigarette smoking and inflammatory gene polymorphisms on glycated hemoglobin in the Japanese general population" (2016)
  • Author(s): Nishida Y, Hara M, Sakamoto T, Shinchi K, Kawai S, Naito M, Hamajima N, Kadota A, Suzuki S, Ibusuki R, Hirata A, Yamaguchi M, Kuriyama N, Oze I, Mikami H, Kubo M, Tanaka H.
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• [Journal Article] Validity of a food frequency questionnaire in a population with high alcohol consumption in Japan. (2016)
  • Author(s): Nakahata NT, Takada AN, Imaeda N, Goto C, Kuwabara KH, Niimura H, Arai Y, Yoshita K, Takezaki T
  • Journal Title: Asia Pac J Clin Nutr Volume: 25 Pages: 195-201
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• [Journal Article] Positive association of plasma homocysteine with cardio-ankle vascular index in a prospective study of Japanese men from the general population. (2016)
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• [Journal Article] The relation of postprandial plasma glucose and serum endostatin to the urinary albumin excretion of residents with prediabetes: results from the Kyushu and Okinawa Population Study (KOPS) (2016)
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  • Journal Title: Int Urol Nephrol Volume: ahead of print Pages: -
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• [Journal Article] Positive linear dose-response relationships, but no J-shaped relationship, between drinking habits and estimated glomerular filtration rate in middle-aged Japanese men. (2016)
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  • Journal Title: Alcohol Volume: 51 Pages: 71-7
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• [Journal Article] Changes of tryptophan metabolism in Japanese runners during an ultramarathon race. (2016)
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  • Journal Title: Sport Sci Health Volume: 12 Pages: 77-83
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• [Journal Article] Rapid detection of germline mutations for hereditary gastrointestinal polyposis/cancers using HaloPlex target enrichment and high-throughput sequencing technologies. (2016)
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• [Journal Article] Identification of a Japanese Lynch syndrome patient with large deletion in the 3' region of the EPCAM gene. (2016)
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• [Journal Article] Lower prevalence of Lynch syndrome in colorectal cancer patients in a Japanese hospital-based population. (2016)
  • Author(s): Kumamoto K, Ishida H, Suzuki O, Tajima Y, Chika N, Kuwabara K, Ishibashi K, Saito K, Nagata K, Eguchi H, Tamaru J, Iwama T.
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• [Journal Article] Clinical impacts of mesothelin expression in gastrointestinal carcinomas. (2016)
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• [Journal Article] microRNA-203 suppresses invasion and epithelial-mesenchymal transition induction via targeting NUAK1 in head and neck cancer. (2016)
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• [Journal Article] Genetic Polymorphisms of CYP2A6 in a Case-Control Study on Bladder Cancer in Japanese Smokers. (2016)
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• [Journal Article] Functional Evaluation of Nine Missense-Type Variants of the Human DNA Glycosylase Enzyme MUTYH in the Japanese Population. (2016)
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• [Journal Article] Clinical significance of PD-L1 and PD-L2 copy number gains in non-small-cell lung cancer (2016)
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• [Journal Article] Establishment of patient-derived cancer xenografts in immunodeficient NOG mice. (2015)
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• [Journal Article] Association of microRNA-31-5p with clinical efficacy of anti-EGFR therapy in patients with metastatic colorectal cancer. (2015)
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• [Journal Article] Low-frequency IL23R coding variant associated with Crohn’s disease susceptibility in Japanese subjects identified by personal genomics analysis. (2015)
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• [Journal Article] Analysis of the molecular features of rectal carcinoid tumors to identify new biomarkers that predict biological malignancy. (2015)
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• [Journal Article] Role of interleukin-32 in the mechanism of chronic inflammation in IgG4-related disease and as a predictive biomarker for drug-free remission. (2015)
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• [Journal Article] Everyday clinical practice in IgG4-related dacryoadenitis and/or sialadentist: Result from the SMART database. (2015)
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  • Journal Title: Modern Rheumatology Volume: 25(2) Pages: 199-204
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• [Journal Article] Schwann cells contribute to neurodegeneration of transthyretin amyloidosis. (2015)
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• [Journal Article] CHF5074 (CSP-1103) stabilizes human transthyretin in mice humanized at the transthyretin and retinol-binding protein loci. (2015)
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• [Journal Article] Requirement of DLG1 for cardiovascular development and tissue elongation during cochlear, enteric, and skeletal development: possible role in convergent extension. (2015)
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• [Journal Article] Roles of hepatic glucokinase in intertissue metabolic communication: examination of novel liver-specific glucokinase knockout mice. (2015)
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• [Journal Article] SPINK1 status in colorectal cancer, impact on proliferation, and role in colitis-associated cancer. (2015)
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• [Journal Article] Mechanism for increased hepatic glycerol synthesis in the citrin/mitochondrial glycerol-3-phosphate dehydrogenase double-knockout mouse: Urine glycerol and glycerol 3-phosphate as potential diagnostic markers of human citrin deficiency. (2015)
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• [Journal Article] Pathophysiological significance of the two-pore domain K+ channel K2P5.1 in splenic CD4+CD25- T cell subset from a chemically-induced murine inflammatory bowel disease model. (2015)
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• [Journal Article] Meikin is a conserved regulator of meiosis-I-specific kinetochore function. (2015)
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• [Journal Article] Determining c-Myb protein levels can isolate functional hematopoietic stem cell subtypes. (2015)
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• [Journal Article] Perinatal Gjb2 gene transfer rescues hearing in a mouse model of hereditary deafness. (2015)
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• [Journal Article] Cysteine analogs with a free thiol group promote fertilization by reducing disulfide bonds in the zona pellucida of mice. (2015)
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• [Journal Article] Efficacy of 2-Hydroxypropyl-β-cyclodextrin in Niemann-Pick Disease Type C Model Mice and Its Pharmacokinetic Analysis in a Patient with the Disease. (2015)
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• [Journal Article] Superovulation using the combined administration of inhibin antiserum and equine chorionic gonadotropin increases the number of ovulated oocytes in C57BL/6 female mice. (2015)
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  • DOI: 10.1371/journal.pone.0128330
  • Peer Reviewed / Open Access
• [Journal Article] HPGCD outperforms HPBCD as a potential treatment for niemann-pick disease type C during disease modeling with iPS cells. (2015)
  • Author(s): Soga M, Ishitsuka Y, Hamasaki M, Yoneda K, Furuya H, Matsuo M, Ihn H, Fusaki N, Nakamura K, Nakagata N, Endo F, Irie T, Era T.
  • Journal Title: Stem Cells Volume: 33(4) Pages: 1075-1088
  • DOI: 10.1002/stem.1917
  • Peer Reviewed
• [Journal Article] Production of knockout mice by DNA microinjection of various CRISPR/Cas9 vectors into freeze-thawed fertilized oocytes. (2015)
  • Author(s): Nakagawa Y, Sakuma T, Sakamoto T, Ohmuraya M, Nakagata N, Yamamoto T.
  • Journal Title: BMC Biotechnol Volume: 15 Pages: 33
  • DOI: 10.1186/s12896-015-0144-x
  • Peer Reviewed / Open Access
• [Journal Article] Region-specific regulation of cell proliferation by FGF receptor signaling during the Wolffian duct development (2015)
  • Author(s): Okazawa M, Murashima A, Harada M, Nakagata N, Noguchi M, Morimoto M, Kimura T, Ornitz DM, Yamada G.
  • Journal Title: Developmental Biology Volume: 400(1) Pages: 139-147
  • DOI: 10.1016/j.ydbio.2015.01.023
  • Peer Reviewed
• [Journal Article] Effects of cyclodextrins on GM1-gangliosides in fibroblasts from GM1-gangliosidosis patients. (2015)
  • Author(s): Maeda Y, Motoyama K, Higashi T, Horikoshi Y, Takeo T, Nakagata N, Kurauchi Y, Katsuki H, Ishitsuka Y, Kondo Y, Irie T, Furuya H, Era T, Arima H.
  • Journal Title: J Pharm Pharmacol Volume: 67(8) Pages: 1133-1142
  • DOI: 10.1111/jphp.12405
  • Peer Reviewed / Open Access
• [Journal Article] Tissue-specific roles of FGF signaling in external genitalia development. (2015)
  • Author(s): Harada M, Omori A, Nakahara C, Nakagata N, Akita K, Yamada G.
  • Journal Title: Dev Dyn Volume: 244(6) Pages: 759-773
  • DOI: 10.1002/dvdy.24277
  • Peer Reviewed
• [Journal Article] 研究者と技術者が支える実験動物科学の柱を再考する：遺伝育種の立場から (2015)
  • Author(s): 加藤秀樹
  • Journal Title: 実験動物技術 Volume: 50 Pages: 57-66
• [Journal Article] Asbestos and multi-walled carbon nanotubes generate distinct oxidative responses in inflammatory cells. (2015)
  • Author(s): Funahashi F, Okazaki Y, Ito D, Asakawa A, Nagai H, Tajima M and Toyokuni S.
  • Journal Title: J Clin Biochem Nutr Volume: 56 Pages: 11-117
  • DOI: 10.3164/jcbn.14-92.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Minimal inflammogenicity of pristine single-wall carbon nanotubes. (2015)
  • Author(s): Toyokuni S, Jiang L, Kitaura R and Shinohara S.
  • Journal Title: Nagoya J Med Sci Volume: 77 Pages: 195-202
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Receptor role of annexin A2 in the mesothelial endocytosis of crocidolite fibers. (2015)
  • Author(s): Yamashita K, Nagai H and Toyokuni S.
  • Journal Title: Lab Invest Volume: 95 Pages: 749-764
  • DOI: 10.1038/labinvest.2015.28.
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Malignant mesothelioma as an oxidative stress-induced cancer: An update. (2015)
  • Author(s): Chew SH and Toyokuni S.
  • Journal Title: Free Radic Biol Med Volume: 86 Pages: 166-178
  • DOI: 10.1016/j.freeradbiomed.2015.05.002.
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] A trial to find appropriate animal models of dichloropropane-induced cholangiocarcinoma based on the hepatic distribution of glutathione S-transferases. (2015)
  • Author(s): Zhang L, Zong C, Ichihara S, Naito H, Toyokuni S, Kumagai S, Ichihara G.
  • Journal Title: J Occup Health Volume: 57 Pages: 548-554
  • DOI: 10.1539/joh.15-0085-OA.
  • Peer Reviewed / Open Access
• [Journal Article] Paraneoplastic Ma Antigen-Like 1 as a Potential Prognostic Biomarker in Human Pancreatic Ductal Adenocarcinoma (2015)
  • Author(s): Kuwae Y, Kakehashi A, Wakasa K, Wei M, Yamano S, Ishii N, Ohsawa M, Wanibuchi H
  • Journal Title: Pancreas Volume: 44 Pages: 106-115
  • DOI: 10.1097/MPA.0000000000000220.
  • Peer Reviewed
• [Journal Article] Determination of Hepatotoxicity and Its Underlying Metabolic Basis of 1,2-Dichloropropane in Male Syrian Hamsters and B6C3F1 Mice (2015)
  • Author(s): Gi M, Fujioka M, Yamano S, Shimomura E, Ishii N, Kakehashi A, Takeshita M, Wanibuchi H
  • Journal Title: Toxicol Sci Volume: 145 Pages: 196-208
  • DOI: 10.1093/toxsci/kfv045.
  • Peer Reviewed
• [Journal Article] Modifying effects of 1,2-dichloropropane on N-nitrosobis(2-oxopropyl)amine-induced cholangiocarcinogenesis in male Syrian hamsters (2015)
  • Author(s): Gi M, Fujioka M, Yamano S, Shimomura E, Kanki M, Kawachi S, Tachibana H, Tatsumi K, Fang H, Ishii N, Kakehashi A, Wanibuchi H.
  • Journal Title: J Toxicol Sci. Volume: 40 Pages: 647-656
  • DOI: 10.2131/jts.40.647.
  • Peer Reviewed / Open Access
• [Journal Article] Chemokine (C-C motif) ligand 3 detection in the serum of persons exposed to asbestos: A patient-based study. (2015)
  • Author(s): Xu, J., Alexander, D. B., Iigo, M., Hamano, H., Takahashi, S., Yokoyama, T., Kato, M., Usami, I., Tokuyama, T., Tsutsumi, M., Tamura, M., Oguri, T., Niimi, A., Hayashi, Y., Yokoyama, Y., Tonegawa, K., Fukamachi, K., Futakuchi, M., Sakai, Y., Suzui, M. et al.
  • Journal Title: Cancer Sci Volume: 106 Pages: 825-832
  • DOI: 10.1111/cas.12687
  • Peer Reviewed
• [Journal Article] In vivo 18F‐fluorodeoxyglucose‐positron emission tomography/computed tomography imaging of pancreatic tumors in a transgenic rat model carrying the human KRASG12V oncogene (2015)
  • Author(s): Shibata, K., Fukamachi, K., Tsuji, T., Saga, T., Futakuchi, M., Nagino, M., Tsuda, H., and Suzui, M.
  • Journal Title: Oncology Letters Volume: 9 Pages: 2112-2118
  • Peer Reviewed
• [Journal Article] Murine Herc6 Plays a Critical Role in Protein ISGylation In Vivo and Has an ISGylation-Independent Function in Seminal Vesicles. (2015)
  • Author(s): Arimoto, K., Hishiki, T., Kiyonari, H., Abe, T., Cheng, C., Yan, M., Fan, J. B., Futakuchi, M., Tsuda, H., Murakami, Y., Suzuki, H., Zhang, D. E., and Shimotohno, K
  • Journal Title: Journal of interferon & cytokine research Volume: 35 Pages: 351-358
  • DOI: 10.1089/jir.2014.0113
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Mutual reinforcement of inflammation and carcinogenesis by the Helicobacter pylori CagA oncoprotein (2015)
  • Author(s): Suzuki N, Murata-Kamiya N, Yanagiya K, Suda W, Hattori M, Kanda H, Bingo A, Fujii Y, Maeda S, Koike K, Hatakeyama M.
  • Journal Title: Scientific Reports Volume: 5 Pages: 10024
  • DOI: 10.1038/srep10024
  • Peer Reviewed / Open Access
• [Journal Article] Ablation of the p16(INK4a) tumor suppressor reverses ageing phenotypes of klotho mice. (2015)
  • Author(s): Sato S, Kawamata Y, Takahashi A, Imai Y, Hanyu A, Okuma A, Takasugi M, Yamakoshi K, Sorimachi H, Kanda H, Ishikawa Y, Sone S, Nishioka Y, Ohtani N, Hara E
  • Journal Title: Nat Commun. Volume: 29 Pages: 7035
  • DOI: 10.1038/ncomms8035
  • Peer Reviewed / Open Access
• [Journal Article] Inhibition of β-catenin and STAT3 with curcumin analog suppresses gastric carcinogenesis in vivo: a novel candidate for gastric cancer treatment (2015)
  • Author(s): Uehara, Y., Inoue, M., Fukuda, K., Yamakoshi, H., Hosoi, Y., Kanda, H., Oshima, M., Iwabuchi, Y., Shibata, H.
  • Journal Title: Gastric Cancer Volume: 18 Pages: 774-783
  • DOI: 10.1007/s10120-014-0434-3.
  • Peer Reviewed / Open Access
• [Journal Article] Reducing DNA methylation suppresses colon carcinogenesis by inducing tumor cell differentiation. Carcinogenesis. (2015)
  • Author(s): Hatano Y, Semi K, Hashimoto K, Lee MS, Hirata A, Tomita H, Kuno T, Takamatsu M, Aoki K, Taketo MM, Kim YJ, Hara A, Yamada Y.
  • Journal Title: Carcinogenesis Volume: 36 Pages: 719-29
  • DOI: 10.1093/carcin/bgv060.
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Induced pluripotent stem cell technology for dissecting the cancer epigenome. (2015)
  • Author(s): Semi K, Yamada Y.
  • Journal Title: Cancer Sci Volume: 106 Pages: 1251-6
  • DOI: 10.1111/cas.12758
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] KLF4 N-terminal variance modulates induced reprogramming to pluripotency. (2015)
  • Author(s): Kim SI, Oceguera-Yanez F, Hirohata R, Linker S, Okita K, Yamada Y, Yamamoto T, Yamanaka S, Woltjen K.
  • Journal Title: Stem Cell Reports Volume: 4 Pages: 727-43
  • DOI: 10.1016/j.stemcr.2015.02.004.
  • Peer Reviewed / Open Access
• [Journal Article] Cigarette smoke inhalation and risk of lung cancer: a case-control study in a large Japanese population. (2015)
  • Author(s): Fukumoto K, Ito H, Matsuo K, Tanaka H, Yokoi K, Tajima K, Takezaki T.
  • Journal Title: Eur J Cancer Prev Volume: 24(3) Pages: 195-200
  • DOI: 10.1097/CEJ.0000000000000034
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Genetic variants of SLC17A1 are associated with cholesterol homeostasis and hyperhomocysteinaemia in Japanese men (2015)
  • Author(s): Koyama, T. Matsui, D. Kuriyama, N. Ozaki, E. Tanaka, K. Oze, I. Hamajima, N. Wakai, K. Okada, R. Arisawa, K. Mikami, H. Shimatani, K. Hirata, A. Takashima, N. Suzuki, S. Nagata, C. Kubo, M. Tanaka, H.
  • Journal Title: Sci Rep Volume: 5 Pages: 15888
  • DOI: 10.1038/srep15888
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Declining trends in prevalence of Helicobacter pylori infection by birth-year in a Japanese population (2015)
  • Author(s): Watanabe, M. Ito, H. Hosono, S. Oze, I. Ashida, C. Tajima, K. Katoh, H. Matsuo, K. Tanaka, H.
  • Journal Title: Cancer Sci Volume: 106(12) Pages: 1738-43
  • DOI: 10.1111/cas.12821
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Association between brain-muscle-ARNT-like protein-2 (BMAL2) gene polymorphism and type 2 diabetes mellitus in obese Japanese individuals: A cross-sectional analysis of the Japan Multi-institutional Collaborative Cohort Study (2015)
  • Author(s): Yamaguchi, M. Uemura, H. Arisawa, K. Katsuura-Kamano, S. Hamajima, N. Hishida, A. Suma, S. Oze, I. Nakamura, K. Takashima, N. Suzuki, S. Ibusuki, R. Mikami, H. Ohnaka, K. Kuriyama, N. Kubo, M. Tanaka, H. Japan Multi-institutional Collaborative Cohort Study, Group
  • Journal Title: Diabetes Res Clin Pract Volume: 110(3) Pages: 301-308
  • DOI: 10.1016/j.diabres.2015.10.009
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] ATP-binding cassette transporter A1 (ABCA1) R219K (G1051A, rs2230806) polymorphism and serum high-density lipoprotein cholesterol levels in a large Japanese population: cross-sectional data from the Daiko Study (2015)
  • Author(s): Mokuno J, Hishida A, Morita E, Sasakabe T, Hattori Y, Suma S, Okada R, Kawai S, Naito M, Wakai K
  • Journal Title: Endocr J Volume: 62 Pages: 543-549
  • DOI: 10.1507/endocrj.EJ14-0577
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Effects of IL6 C-634G polymorphism on tooth loss and their interaction with smoking habits (2015)
  • Author(s): Suma S, Naito M, Wakai K, Sasakabe T, Hattori Y, Okada R, Kawai S, Hishida A ,Morita E, Nakagawa H, Tamura T, Hamajima N
  • Journal Title: Oral Dis Volume: 21 Pages: 807-813
  • DOI: 10.1111/odi.12352
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] No association between Helicobacter pylori infection and diabetes mellitus among a general Japanese population: a cross-sectional study (2015)
  • Author(s): Tamura T, Morita E, Kawai S, Sasakabe T, Sugimoto Y, Fukuda N, Suma S, Nakagawa H, Okada R, Hishida A, Naito M, Hamajima N, Wakai K
  • Journal Title: Springerplus Volume: 4 Pages: 602
  • DOI: 10.1186/s40064-015-1371-2
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] GGT1 intronic A>G polymorphism affects setum concentration of γ-glutamyl transpeptidase among Japanese healthy adults (2015)
  • Author(s): Kawai S, Naito M, Morita E, Okada R, Hishida A, Wakai K, Hamajima N
  • Journal Title: Ningen Dock International Volume: 2 Pages: 65-69
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Polymorphisms in CYP19A1, HSD17B1 and HSD17B2 genes and serum sex hormone level among postmenopausal Japanese women. Japan Multi-Institutional Collaborative Cohort (J-MICC) Study Group. (2015)
  • Author(s): Hosono S, Ito H, Oze I, Higaki Y, Morita E, Takashima N, Suzuki S, Shimatani K, Mikami H, Ohnaka K, Ozaki E. Katsuura-Kamano S, Kubo M, Nagata C, Naito M, Hamajima N, Tanaka H.
  • Journal Title: Maturitas. Volume: 82 Pages: 394-401
  • DOI: 10.1016/j.maturitas.2015.08.003
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Serologically Determined Gastric Mucosal Condition Is a Predictive Factor for Osteoporosis in Japanese Men. (2015)
  • Author(s): Shigeto Mizuno, Daisuke Matsui, Isao Watanabe, Etsuko Ozaki, Nagato Kuriyama, Yoshiyuki Watanabe.
  • Journal Title: Digestive Diseases and Sciences Volume: 7 Pages: 2063-2069
  • DOI: 10.1007/s10620-015-3576-1
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Relationship between Cnm-positive Streptococcus mutans and cerebral microbleeds in humans. (2015)
  • Author(s): Miyatani F, Kuriyama N, Watanabe I, Nomura R, Nakano K, Matsui D, Ozaki E, Koyama T, Nishigaki M, Yamamoto T, Mizuno T, Tamura A, Akazawa K, Takada A, Takeda K, Yamada K, Nakagawa M, Ihara M, Kanamura N, Friedland RP, Watanabe Y
  • Journal Title: Oral Diseases Volume: 21 Pages: 886-893
  • DOI: 10.1111/odi.12360
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Factor associated with non-participation in face-to-face survey conducted 5 years after baseline survey. (2015)
  • Author(s): Hara M, Shimanoe C, Otsuka Y, Nishida Y, Nanri H, Horita M, Yasukata J, Miyoshi N, Yamada Y, Higaki Y, Tanaka K.
  • Journal Title: J. Epidemiol. Volume: 25 Pages: 117-125
  • DOI: 10.2188/jea.JE20140116
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Genetic variants of SLC17A1 are associated with cholesterol homeostasis and hyperhomocysteinemia in Japanese men. (2015)
  • Author(s): Koyama T, Matsui D, Kuriyama N, Ozaki E, Tanaka K, Oze I, Hamajima N, Wakai K, Okada R, Arisawa K, Mikami H, Shimatani K, Hirata A, Takashima N, Suzuki S, Nagata C, Kubo M, Tanaka H
  • Journal Title: Sci. Rep. Volume: 5 Pages: 15888
  • DOI: 10.1038/srep15888
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Dietary patterns and serum gamma-glutamyl transferase in Japanese men and women. (2015)
  • Author(s): Nanri H, Hara M, Nishida Y, Shimanoe C, Nakamura K, Higaki Y, Imaizumi T, Taguchi N, Sakamoto T, Horita M, Shinchi K, Kokaze A, Tanaka K
  • Journal Title: J. Epidemiol. Volume: 25 Pages: 378-386
  • DOI: 10.2188/jea.JE20140158
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Perceived stress and coping strategies in relation to body mass index: cross-sectional study of 12,045 Japanese men and women (2015)
  • Author(s): Shimanoe C, Hara M, Nishida Y, Nanri H, Otsuka Y, Nakamura K, Higaki Y, Imaizumi T, Taguchi N, Sakamoto T, Horita M, Shinchi K, Tanaka K.
  • Journal Title: Plos One Volume: 10 Pages: e0118105
  • DOI: 10.1371/journal.pone.0118105
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Incidence, serum IgE and TARC/CCL17 levels of atopic dermatitis in association with other related allergic diseases: An update from the Ishigaki Island cohort. (2015)
  • Author(s): Takeuchi S, Esaki H, Furusyo N, Hayashida S, Yamamura K, Tsuji G, Takemura M, Hayashi J, Furue M:
  • Journal Title: Acta Dermato Venereologica Volume: 95 Pages: 480-484
  • DOI: 10.2340/00015555-1989
  • Peer Reviewed
• [Journal Article] Non-invasive fibrosis assessment predicts sustained virological response to telaprevir with pegylated interferon and ribavirin for chronic hepatitis C. (2015)
  • Author(s): Ogawa E, Furusyo N, Shimizu M, Ihara T, Hayashi T, Harada Y, Toyoda K, Murata M, Hayashi J:
  • Journal Title: Antiviral Therapy Volume: 20 Pages: 185-192
  • DOI: 10.3851/IMP2805.
  • Peer Reviewed
• [Journal Article] Predictors of kidney tubular dysfunction by adefovir for chronic hepatitis B (2015)
  • Author(s): Shimizu M, Furusyo N, Ikezaki H, Ogawa E, Hayashi T, Ihara T, Harada Y, Toyoda T, Murata M, Hayashi J:
  • Journal Title: World Journal of Gastroenterology Volume: 21 Pages: 2116-2123
  • DOI: 10.3748/wjg.v21.i7.2116.
  • Peer Reviewed / Open Access
• [Journal Article] Bacterial infection as an adverse effect of telaprevir-based triple therapy for chronic hepatitis C infection. (2015)
  • Author(s): Kawano A, Ogawa E, Furusyo N, Nakamuta M, Kajiwara E, Dohmen K, Nomura H, Takahashi K, Satoh T, Azuma K, Tanabe Y, Shimoda S, Kotoh K, Hayashi J , The Kyushu University Liver Disease Study (KULDS) Group.
  • Journal Title: Internal Medicine Volume: 54 Pages: 567-572
  • DOI: 10.2169/internalmedicine.54.3457.
  • Peer Reviewed / Open Access
• [Journal Article] The kinetics of the hepatitis B surface antigen level after the initiation of antiretroviral therapy for hepatitis B virus and human immunodeficiency virus coinfected patients. (2015)
  • Author(s): Mitsumoto F, Murata M, Ura K, Takayama K, Hiramine S, Shimizu M, Toyoda K, Ogawa E, Furusyo N, Hayashi J:
  • Journal Title: Journal of Infection and Chemotherapy Volume: 21 Pages: 264-271
  • DOI: 10.1016/j.jiac.2014.12.003.
  • Peer Reviewed
• [Journal Article] Direct acting antiviral agent-based therapy effectively decreases the serum alpha fetoprotein level of chronic hepatitis C patients (2015)
  • Author(s): Takayama K, Furusyo N, Ogawa E, Ikezaki H, Shimizu M, Masayuki M, Hayashi J.
  • Journal Title: World Journal of Gastroenterology Volume: 21 Pages: 4696-4706
  • DOI: 10.3748/wjg.v21.i15.4696
  • Peer Reviewed / Open Access
• [Journal Article] Glycated Albumin as a diagnostic tool for diabetes in a general population. (2015)
  • Author(s): Ikezaki H, Furusyo N, Ihara T, Hayashi T, Ura K, Hiramine S, Mitsumoto F, Takayama K, Murata M, Kohzuma T, Ai M, Schaefer EJ, Hayashi J.
  • Journal Title: Metabolism Volume: 64 Pages: 698-705
  • DOI: 10.1016/j.metabol.2015.03.003.
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] A thymine-adenine dinucleotide repeat polymorphism near IL28B is associated with spontaneous clearance of hepatitis C virus. (2015)
  • Author(s): Hiramine S, Sugiyama M, Furusyo N, Uto H, Ido A, Tsubouchi H, Watanabe H, Ueno Y, Korenaga M, Murata K, Masaki N, Hayashi J, Thomas DL, Mizokami M.
  • Journal Title: Journal of Gastroenterology Volume: 50 Pages: 1069-1077
  • DOI: 10.1007/s00535-015-1056-1.
  • Peer Reviewed
• [Journal Article] Comparative safety study on severe anemia by simeprevir- versus telaprevir-based triple therapy for chronic hepatitis C. (2015)
  • Author(s): Ogawa E, Furusyo N, Kajiwara E, Nomura H, Kawano A, Takahashi K, Dohmen K, Satoh T, Azuma K, Nakamuta M, Koyanagi T, Kotoh K, Shimoda S, Hayashi J, The Kyushu University Liver Disease Study (KULDS) Group.
  • Journal Title: Journal of Gastroenterology and Hepatology Volume: 30 Pages: 1309-1316
  • DOI: 10.1111/jgh.12945.
  • Peer Reviewed
• [Journal Article] Effectiveness of triple therapy with simeprevir for chronic hepatitis C genotype 1b patients with prior telaprevir failure. (2015)
  • Author(s): Ogawa E, Furusyo N, Dohmen K, Kajiwara E, Kawano A, Nomura H, Takahashi K, Satoh T, Azuma K, Nakamuta M, Koyanagi T, Kotoh K, Shimoda S, Hayashi J; The Kyushu University Liver Disease Study (KULDS) Group.
  • Journal Title: Journal of Viral Hepatitis Volume: 22 Pages: 992-1001
  • DOI: 10.1111/jvh.12427.
  • Peer Reviewed
• [Journal Article] Comparative effectiveness and safety study of triple therapy with simeprevir or telaprevir for non-cirrhotic patients with chronic hepatitis C virus genotype 1b infection. (2015)
  • Author(s): Ogawa E, Furusyo N, Dohmen K, Kajiwara E, Kawano A, Nomura H, Takahashi K, Satoh T, Azuma K, Nakamuta M, Koyanagi T, Kotoh K, Shimoda S, Hayashi J; The Kyushu University Liver Disease Study (KULDS) Group.
  • Journal Title: Journal of Gastroenterology and Hepatology Volume: 30 Pages: 1759-1767
  • DOI: 10.1111/jgh.13016.
  • Peer Reviewed
• [Journal Article] Efficacy of interferon-beta plus ribavirin combination treatment on the development of hepatocellular carcinoma by Japanese patients with chronic hepatitis C. (2015)
  • Author(s): Ikezaki H, Nomura H, Furusyo N, Ogawa E, Kajiwara E, Takahashi K, Kawano A, Maruyama T, Tanabe Y, Satoh T Nakamuta M, Kotoh K, Azuma K, Dohmen K, Shimoda S, Hayashi J; The Kyushu University Liver Disease Study (KULDS) Group.
  • Journal Title: Hepatology Research Volume: 46 Pages: E174-E180
  • DOI: 10.1111/hepr.12555
  • Peer Reviewed
• [Journal Article] Importance of virological response in the early stage of telaprevir-based triple therapy (2015)
  • Author(s): Hiramine S, Furusyo N, Ogawa E, Nakamuta M, Kajiwara E, Nomura H, Dohmen K, Takahashi K, Satoh T, Azuma K, Kawano A, Koyanagi T, Kotoh K, Shimoda S, Hayashi J
  • Journal Title: World Journal of Hepatology Volume: 7 Pages: 2688-2695
  • DOI: 10.4254/wjh.v7.i26.2688.
  • Peer Reviewed / Open Access
• [Journal Article] The association between objective tongue color and endoscopic findings: results from the Kyushu and Okinawa population study (KOPS). (2015)
  • Author(s): Kainuma M, Furusyo N, Urita Y, Nagata M, Ihara T, Oji T, Nakaguchi T, Namiki T, Hayashi J.
  • Journal Title: BMC Complementary and Alternative Medicine Volume: 15 Pages: 372
  • DOI: 10.1186/s12906-015-0904-0.
  • Peer Reviewed / Open Access
• [Journal Article] Epigenome-wide association study suggests that SNPs in the promoter region of RETN influence plasma resistin level via effects on DNA methylation at neighbouring sites (2015)
  • Author(s): Nakatochi M, Ichihara S, Yamamoto K, Ohnaka K, Kato Y, Yokota S, Hirashiki A, Naruse K, Asano H, Izawa H, Matsubara T, Yokota M.
  • Journal Title: Diabetologia Volume: 58(12) Pages: 2781-2790
  • DOI: 10.1007/s00125-015-3763-9
  • Peer Reviewed / Open Access
• [Journal Article] Inter- and intra-individual variations in seasonal and daily stabilities of the human gut microbiota in Japanese. (2015)
  • Author(s): Hisada T, Endoh K, Kuriki K.
  • Journal Title: Arch Microbiol. Volume: 197 Pages: 919-34
  • DOI: 10.1007/s00203-015-1125-0.
  • Peer Reviewed / Open Access
• [Journal Article] Interactions between Psychological Stress and Drinking Status in Relation to Diet among Middle-Aged Men and Women: A Large-Scale Cross-Sectional Study in Japan. (2015)
  • Author(s): Endoh K, Kuriki K, Kasezawa N, Tohyama K, Goda T.
  • Journal Title: J Nutr Sci Vitaminol (Tokyo) Volume: 61 Pages: 64-72
  • DOI: 10.3177/jnsv.61.64.
  • Peer Reviewed / Open Access
• [Journal Article] Association between Smoking Status and Food and Nutrient Consumption in Japanese: a Large-Scale Cross-Sectional Study. (2015)
  • Author(s): Endoh K, Kuriki K, Kasezawa N, Tohyama K, Goda T.
  • Journal Title: Asian Pac J Cancer Prev. Volume: 16(15) Pages: 6527-34
  • Peer Reviewed / Open Access
• [Journal Article] The A Allele at rs13419896 of EPAS1 Is Associated with Enhanced Expression and Poor Prognosis for Non-Small Cell Lung Cancer. (2015)
  • Author(s): Putra AC, Eguchi H, Lee KL, Yamane Y, Gustine E, Isobe T, Nishiyama M, Hiyama K, Poellinger L, Tanimoto K.
  • Journal Title: PLoS One. Volume: 10 Pages: e0134496.
  • DOI: 10.1371/journal.pone.0134496
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Association of hair dye use with circulating levels of sex hormones in premenopausal Japanese women. (2015)
  • Author(s): Nagata C, Wada K, Tsuji M, Hayashi M, Takeda N, Yasuda K.
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  • DOI: 10.1093/eurpub/ckv020.
  • Peer Reviewed
• [Journal Article] Establishiment of Tsc2-deficient rat embryonic stem cells. (2015)
  • Author(s): Ito Y., Kawano H., Kanai F., Nakamura E., Tada N., Takai S., Horie S., Arai H., Kobayashi T. & Hino O
  • Journal Title: Int. J. Oncology Volume: 46 Pages: 1944-1952
  • DOI: 10.3892/ijo.2015.2913
  • Peer Reviewed
• [Journal Article] Environmental carcinognensis-100th anniversary of creating cancer. (2015)
  • Author(s): Imai M. and Hino O
  • Journal Title: Cancer Science Volume: 106 Pages: 1483-1485
  • DOI: 10.1111/cas.12798
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• [Journal Article] Telomere G-tail Length is a Promising Biomarker Related to White Matter Lesions and Endothelial Dysfunction in Patients With Cardiovascular Risk: A Cross-sectional Study. (2015)
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  • Journal Title: EBioMedicine. Volume: 2(8) Pages: 958-65.
  • DOI: 10.1016/j.ebiom.2015.05.025.
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Mutations in the gene encoding the E2 conjugating enzyme UBE2T cause Fanconi anemia. (2015)
  • Author(s): Hira A, Yoshida K, Sato K, Okuno Y, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Shimamoto A, Tahara H, Ito E, Kojima S, Kurumizaka H, Ogawa S, Takata M, Yabe H, Yabe M.
  • Journal Title: Am J Hum Genet. Volume: 96(6) Pages: 1001-7.
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• [Journal Article] "Werner Syndrome-specific induced pluripotent stem cells: recovery of telomere function by reprogramming. " (2015)
  • Author(s): Shimamoto A, Yokote K, Tahara H.
  • Journal Title: Front Genet. Volume: 6 Pages: 10
  • DOI: 10.3389/fgene.2015.00010.
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] A potential function for neuronal exosomes: sequestering intracerebral amyloid-β peptide. (2015)
  • Author(s): Yuyama K, Sun H, Usuki S, Sakai S, Hanamatsu H, Mioka T, Kimura N, Okada M, Tahara H, Furukawa J, Fujitani N, Shinohara Y, Igarashi Y.
  • Journal Title: FEBS Lett. Volume: 589(1) Pages: 84-8.
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• [Journal Article] EVpedia: a community web portal for extracellular vesicles research. (2015)
  • Author(s): Kim DK, Lee J, Kim SR, Choi DS, Yoon YJ, Kim JH, Go G, Nhung D, Hong K, Jang SC, Kim SH, Park KS, Kim OY, Park HT, Seo JH, Soekmadji C, Stahl P, Stensballe A, Stepien E, Tahara H, Trummer A, Valadi H, Vella LJ, Wai SN, Witwer K, Yanez-Mo, M, Youn H, Zeidler R, Gho YS.
  • Journal Title: Bioinformatics. Volume: 31(6) Pages: 933-9.
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  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Geographic particularities in incidence and etiopathogenesis of sporadic gastric cancer. (2015)
  • Author(s): Kadar Z, Jung I, Orlowska J, Szentirmay Z, Sugimura H, Turdean S, Simona G.
  • Journal Title: Pol J Pathol. Volume: 66（3） Pages: 254-259
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Clinicopathological and Survival Analysis of Japanese Patients with Resected Non-Small-Cell Lung Cancer Harboring NKX2-1, SETDB1, MET, HER2, SOX2, FGFR1, or PIK3CA Gene Amplification. (2015)
  • Author(s): Inoue Y, Matsuura S, Kurabe N, Kahyo T, Mori H, Kawase A, Karayama M, Inui N, Funai K, Shinmura K, Suda T, Sugimura H.
  • Journal Title: J Thorac Oncol. Volume: 10 Pages: 1590-1600
  • DOI: 10.1097/JTO.0000000000000685.
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] New Insights in Histogenetic Pathways of Gastric Cancer. (2015)
  • Author(s): Gurzu S, Sugimura H, Orlowska J, Szentirmay Z, Jung I.
  • Journal Title: Medicine(Baltimore) Volume: 94 Pages: e1810
  • DOI: 10.1097/MD.0000000000001810.
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Single skip metastasis in sentinel lymph node: In an early gastric cancer. (2015)
  • Author(s): Bara T Jr, Gurzu S, Jung I, Kadar Z, Sugimura H, Bara T.
  • Journal Title: World J Gastroenterol. Volume: 21 Pages: 9803-9807
  • DOI: 10.3748/wjg.v21.i33.9803.
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
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  • Author(s): Nakamura S, Kahyo T, Tao H, Shibata K, Kurabe N, Yamada H, Shinmura K, Ohnishi K, Sugimura H.
  • Journal Title: Sci Rep. Volume: 5 Pages: 13474
  • DOI: 10.1038/srep13474.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Associations between the orexin (hypocretin) receptor 2 gene polymorphism Val308Ile and nicotine dependence in genome-wide and subsequent association studies. (2015)
  • Author(s): Nishizawa D, Sugimura H, et al.
  • Journal Title: Mol Brain. Volume: 8 Pages: 50
  • DOI: 10.1186/s13041-015-0142-x.
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• [Journal Article] Hereditary diffuse gastric cancer--An overview. (2015)
  • Author(s): Gurzu S, Jung I, Orlowska J, Sugimura H, Kadar Z, Turdean S, Bara T Jr.
  • Journal Title: Pathol Res Pract. Volume: 211 Pages: 629-632
  • DOI: 10.1016/j.prp.2015.06.003.
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• [Journal Article] Association between AKT1 Gene Polymorphism rs2498794 and Smoking-Related Traits with reference to Cancer Susceptibility. (2015)
  • Author(s): Nishizawa D, Kasai S, Hasegawa J, Sato N, Tanioka F, Sugimura H, Ikeda K, Dobashi Y.
  • Journal Title: Biomed Res Int. Volume: 2015 Pages: 316829
  • DOI: 10.1155/2015/316829
  • Peer Reviewed / Open Access
• [Journal Article] Validity of Tissue Microarray by Immunohistochemistry. (2015)
  • Author(s): Fujita H, Takayama T, Takaoka N, Tan C, Igarashi H, Sugimura H, Ozono S.
  • Journal Title: Clin Lab. Volume: 61(5-6) Pages: 569-574
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] NEIL1 p.Gln282Stop variant is predominantly localized in the cytoplasm and exhibits reduced activity in suppressing mutations. (2015)
  • Author(s): Shinmura K, Kato H, Kawanishi Y, Goto M, Tao H, Inoue Y, Nakamura S, Sugimura H.
  • Journal Title: Gene. Volume: 571 Pages: 33-42
  • DOI: 10.1016/j.gene.2015.06.043.
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] CYP2A6 genetic polymorphism is associated with decreased susceptibility to squamous cell lung cancer in Japanese smokers. (2015)
  • Author(s): Hosono H, Kumondai M, Arai T, Sugimura H, Sasaki T, Hirasawa N, Hiratsuka M.
  • Journal Title: Drug Metab Pharmacokinet. Volume: 30 Pages: 263-268
  • DOI: 10.1016/j.dmpk.2015.04.002.
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• [Journal Article] BSND and ATP6V1G3: Novel Immunohistochemical Markers for Chromophobe Renal Cell Carcinoma. (2015)
  • Author(s): Shinmura K, Igarashi H, Kato H, Koda K, Ogawa H, Takahashi S, Otsuki Y, Yoneda T, Kawanishi Y, Funai K, Takayama T, Ozono S, Sugimura H.
  • Journal Title: Medicine(Baltimore) Volume: 94(24) Pages: e989
  • DOI: 10.1097/MD.0000000000000989.
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• [Journal Article] Maspin-related Orchestration of Aggressiveness of Gastric Cancer. (2015)
  • Author(s): Gurzu S, Kadar Z, Sugimura H, Orlowska J, Bara T, Bara T Jr, Szederjesi J, Jung I.
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  • DOI: 10.1097/PAI.0000000000000189
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• [Journal Article] SASS6 overexpression is associated with mitotic chromosomal abnormalities and a poor prognosis in patients with colorectal cancer. (2015)
  • Author(s): Shinmura K, Kato H, Kawanishi Y, Nagura K, Kamo T, Okubo Y, Inoue Y, Kurabe N, Du C, Iwaizumi M, Kurachi K, Nakamura T, Sugimura H.
  • Journal Title: Oncol Rep. Volume: 34 Pages: 727-738
  • DOI: 10.3892/or.2015.4014.
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• [Journal Article] "Cytological Features of a Variant NUT Midline Carcinoma of the Lung Harboring the NSD3-NUT Fusion Gene: A Case Report and Literature Review. " (2015)
  • Author(s): Kuroda S, Suzuki S, Kurita A, Muraki M, Aoshima Y, Tanioka F, Sugimura H.
  • Journal Title: Case Rep Pathol. Volume: - Pages: 572951
  • DOI: 10.1155/2015/572951.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] CD44-SLC1A2 fusion transcripts in primary colorectal cancer. (2015)
  • Author(s): Shinmura K, Kato H, Igarashi H, Inoue Y, Nakamura S, Du C, Kurachi K, Nakamura T, Ogawa H, Tanahashi M, Niwa H, Sugimura H.
  • Journal Title: Pathol Oncol Res. Volume: 21 Pages: 759-764
  • DOI: 10.1007/s12253-014-9887-2.
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• [Journal Article] NSD3-NUT-expressing midline carcinoma of the lung: first characterization of primary cancer tissue. (2015)
  • Author(s): Suzuki S, Kurabe N, Ohnishi I, Yasuda K, Aoshima Y, Naito M, Tanioka F, Sugimura H.
  • Journal Title: Pathol Res Pract. Volume: 211 Pages: 404-408
  • DOI: 10.1016/j.prp.2014.
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] The inner centromere-shugoshin network prevents chromosomal instability. (2015)
  • Author(s): Tanno Y, Susumu H, Kawamura M, Sugimura H, Honda T, Watanabe Y.
  • Journal Title: Science Volume: 349 Pages: 1237-1240
  • DOI: 10.1126/science.aaa2655.
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• [Journal Article] Panitumumab for locally advanced head and neck squamouse-cell carcinoma (2015)
  • Author(s): Ishiki H, Iwase S, Shimada N, Chiba T, Imai K
  • Journal Title: Lancet Oncology Volume: 16 Issue: 4 Pages: e156
  • DOI: 10.1016/S1470-2045(15)70101-4
  • Peer Reviewed
• [Journal Article] Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis (2015)
  • Author(s): Mitsuhashi K, Nosho K, Sukawa Y, Matsunaga Y, Ito M, Kurihara H, Kanno S, Igarashi H, Naito T, Adachi Y, Tachibana M, Tanuma T, Maguchi H, Shinohara T, Hasegawa T, Imamura M, Kimura Y, Hirata K, Maruyama R, Suzuki H, Imai K, Yamamoto H, Shinomura Y
  • Journal Title: Oncotarget
  • Description: 【掲載確定】 in press
  • Peer Reviewed
• [Journal Article] Microsatellite instability : an update (2015)
  • Author(s): Yamamoto H, Imai K
  • Journal Title: Archives of Toxicology
  • Description: 【掲載確定】 in press
  • Peer Reviewed
• [Journal Article] Screening of drugs to treat 8p11 myeloproliferative syndrome using patient-derived induced pluripotent stem cells with fusion gene CEP110-FGFR1 (2015)
  • Author(s): Yamamoto S, Otsu M, Matsuzaka E, Konishi C, Takagi H, Hanada S, Mochizuki S, Nakauchi H, Imai K, Tsuji K, Ebihara Y
  • Journal Title: Plos One
  • Description: 【掲載確定】 in press
  • Peer Reviewed
• [Journal Article] Clinicopathological and molecular characteristics of serrated lesions in Japanese elderly patients (2015)
  • Author(s): Nosho K, Igarashi H, Ito M, Mitsuhashi K, Kurihara H, Kanno S, Yoshii S, Mikami M, Takahashi H, Kusumi T, Hosokawa M, Sukawa Y, Adachi Y, Hasegawa T, Okita K, Hirata K, Maruyama R, Suzuki H, Imai K, Yamamoto H, Shinomura Y
  • Journal Title: Digestion Volume: 91 Issue: 1 Pages: 57-63
  • DOI: 10.1159/000368820
  • Peer Reviewed
• [Journal Article] Contextual niche signals towards colorectal tumor progression by mesenchymal stem cell in the mouse xenograft model (2015)
  • Author(s): Nakagaki S, Arimura Y, Nagaishi K, Isshiki H, Nasuno M, Watanabe S, Idogawa M, Yamashita K, Naishiro Y, Adachi Y, Suzuki H, Fujimiya M, Imai K, Shinomura Y
  • Journal Title: J Gastroenterol
  • Description: 【掲載確定】 Epub ahead of print
  • Peer Reviewed
• [Journal Article] 抗体医薬 (2015)
  • Author(s): 安井寛, 今井浩三
  • Journal Title: DDS研究30年 Volume: PHARMA TECH JAPAN 臨時増刊号,31(2) Pages: 94-101
  • Peer Reviewed
• [Journal Article] 抗体治療 特集「DDSがもたらした新しい臨床の風景」 (2015)
  • Author(s): 佐々木茂, 篠村恭久, 今井浩三
  • Journal Title: Drug Delivery System Volume: 30 Issue: 1 Pages: 16-24
  • Peer Reviewed
• [Journal Article] CHF5074(CSP-1103)stabilizes human transthyretin in mice humanized at the transthyretin and retinol-binding protein loci (2015)
  • Author(s): Mu, Y., Jin, S., Shen, J., Sugano, A., Takaoka, Y., Qiang, L., Imbimbo, B.P., Yamamura, K. and Li, Z.
  • Journal Title: FEBS letters
  • DOI: 10.1016/j.febslet.2015.02.020
  • Description: in press
  • Peer Reviewed
• [Journal Article] Requirement of DLG1 for cardiovascular development and tissue elongation during cochlear, enteric, and skeletal development : possible role in convergent extension (2015)
  • Author(s): Iizuka-Kogo, A., Senda, T., Akiyama, T., Shimomura, A., Nomura, R., Hasegawa, Y., Yamamura, K., Kogo, H., Sawai, N. and Matsuzaki, T.
  • Journal Title: Plos One
  • Description: in press
  • Peer Reviewed
• [Journal Article] Determining c-Myb protein levels can isolate functional hematopoietic stem cell subtypes (2015)
  • Author(s): Sakamoto, H, Takeda, N, Arai, F, Hosokawa, K, Garcia, P, Suda, T, Frampton, J, Ogawa, M
  • Journal Title: Stem Cells Volume: 2 Pages: 479-490
  • DOI: 10.1002/stem.1855
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• [Journal Article] Cysteine analogs with a free thiol group promote fertilization by reducing disulfide bonds in the Zona Pellucida of mice (2015)
  • Author(s): Takeo, T., Horikoshi, Y., Nakao, S., Sakoh, K., Ishizuka, Y., Tsutsumi, A., Fukumoto, K., Kondo, T., Haruguchi, Y., Takeshita, Y., Nakamuta, Y., Tsuchiyama, S. and Nakagata, N.
  • Journal Title: Biol. Reprod. Volume: 92(4)90 Pages: 1-7
  • DOI: 10.1095/biolreprod.114.125443
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• [Journal Article] Minimal inflammogenicity of pristine single-wall carbon nanotubes (2015)
  • Author(s): Toyokuni, S, Jiang, L, Kitaura, R and Shinohara, S
  • Journal Title: Nagoya J Med Sci Volume: 77 Pages: 195-202
  • DOI: 10.3389/fphar.2014.00200
  • Peer Reviewed
• [Journal Article] Percutaneous Carbon Dioxide Treatment using a Gas Mist Generator Enhances the Collateral Blood Flow in the Ischemic Hindlimb (2015)
  • Author(s): Izumi, Y, Yamaguchi, T, Yamazaki, T, Yamashita, N, Nakamura, Y, Shiota, M, Tanaka, M, Sano, S, Osada-Oka, M, Shimada, K, Wanibuchi, H, Miura, K, Yoshiyama, M, Iwao, H
  • Journal Title: J Atheroscler Thromb Volume: 22 Pages: 38-51
  • DOI: 10.5551/jat.23770
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• [Journal Article] Paraneoplastic Ma Antigen-Like 1 as a Potential Prognostic Biomarker in Human Pancreatic Ductal Adenocarcinoma (2015)
  • Author(s): Kuwae, Y, Kakehashi, A, Wakasa, K, Wei, M, Yamano, S, Ishii, N, Ohsawa, M, Wanibuchi, H
  • Journal Title: Pancreas Volume: 44 Pages: 106-115
  • Peer Reviewed
• [Journal Article] Determination of Hepatotoxicity and Its Underlying Metabolic Basis of 1,2-dichloropropane in Male Syrian Hamsters and B6C3F1 Mice (2015)
  • Author(s): Wei, M, Fujioka, M, Yamano, S, Shimomura, E, Ishii, N, Kakehashi, A, Takeshita, M, Wanibuchi, H
  • Journal Title: Toxicol. Sci
  • Description: in press
  • Peer Reviewed
• [Journal Article] Inhibition of β-catenin and STAT3 with curcumin analog suppresses gastric carcinogenesis in vivo : a novel candidate for gastric cancer treatment (2015)
  • Author(s): Uehara, Y., Inoue, M., Fukuda, K., Yamakoshi, H., Hosoi, Y., Kanda, H., Oshima, M., Iwabuchi, Y., Shibata, H.
  • Journal Title: Gastric Cancer
  • DOI: 10.1007/s10120-014-0434-3
  • Description: in press
  • Peer Reviewed
• [Journal Article] NPT1/SLC17A1 is a renal urate exporter in humans and its common gain-of-function variant decreases the risk of renal underexcretion gout (2015)
  • Author(s): Chiba, T., Matsuo H., Kawamura Y., Nagamori S., Nishiyama T., Wei L., Nakayama A., Nakamura T., Sakiyama M., Takada T., Taketani Y., Suma S., Naito M., Oda T., Kumagai H., Moriyama Y., Ichida K., Shimizu T., Kanai Y. and Shinomiya N.
  • Journal Title: Arthritis Rheumatol Volume: 67 Pages: 281-287
  • DOI: 10.1002/art.38884
  • Peer Reviewed
• [Journal Article] Common variant of ALPK1 is not associated with gout : a replication study (2015)
  • Author(s): Chiba, T., Matsuo H., Sakiyama M., Nakayama A., Shimizu S., Wakai K., Suma S., Nakashima H., Sakurai Y., Shimizu T., Ichida K. and Shinomiya N.
  • Journal Title: Hum Cell Volume: 28 Pages: 1-4
  • DOI: 10.1007/s13577-014-0103-1
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• [Journal Article] HLA-A SNPs and amino acid variants are associated with nasopharyngeal carcinoma in Malaysian Chinese (2015)
  • Author(s): Chin, Y.M., Mushiroda T., Takahashi A., Kubo M., Krishnan G., Yap L.F., Teo S.H., Lim P.V., Yap Y.Y., Pua K.C., Kamatani N., Nakamura Y., Sam C.K., Khoo A.S., Malaysian N.P.C.S.G. and Ng C.C.
  • Journal Title: Int J Cancer Volume: 136 Pages: 678-687
  • DOI: 10.1002/ijc.29035
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• [Journal Article] Syndecan-1 responsive microRNA-126 and 149 regulate cell proliferation in prostate cancer (2015)
  • Author(s): Fujii, T., Shimada K., Tatsumi Y., Fujimoto K. and Konishi N.
  • Journal Title: Biochem Biophys Res Commun Volume: 456 Pages: 183-189
  • DOI: 10.1016/j.bbrc.2014.11.056
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• [Journal Article] Fine-Scale Mapping of the 5q11.2 Breast Cancer Locus Reveals at Least Three Independent Risk Variants Regulating MAP3K1 (2015)
  • Author(s): Glubb, D.M., Maranian M.J., Michailidou K., Pooley K.A., Meyer K.B., Kar S., Carlebur S., O'Reilly M., Betts J.A., Hillman K.M., Kaufmann S., Beesley J., Hopper J.L., Southey M.C., Apicella C., Schmidt M.K., Matsuo K., Ito H., Iwata H., Tanaka H., et al.
  • Journal Title: Am J Hum Genet Volume: 96 Pages: 5-20
  • DOI: 10.1016/j.ajhg.2014.11.009
  • Peer Reviewed
• [Journal Article] Gastric cancer in young vs old Romanian patients : immunoprofile with emphasis on maspin and mena protein reactivity (2015)
  • Author(s): Gurzu, S., Kadar Z., Sugimura H., Bara T., Bara T., Jr., Halmaciu I. and Jung I.
  • Journal Title: APMIS Volume: 123 Pages: 223-233
  • DOI: 10.1111/apm.12347
  • Peer Reviewed
• [Journal Article] Factors Associated With Non-participation in a Face-to-Face Second Survey Conducted 5 Years After the Baseline Survey (2015)
  • Author(s): Hara, M., Shimanoe C., Otsuka Y., Nishida Y., Nanri H., Horita M., Yasukata J., Miyoshi N., Yamada Y., Higaki Y. and Tanaka K.
  • Journal Title: J Epidemiol Volume: 25 Pages: 117-125
  • DOI: 10.2188/jea.JE20140116
  • Peer Reviewed
• [Journal Article] Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci (2015)
  • Author(s): He, M., Xu M., Zhang B., Liang J., Chen P., Lee J.Y., Kubo M., A., Li H., Yang X., Dai J., Liang L., Gui L., Qi Q., Huang J., Okada Y., Takeuchi F., Tanaka T., Yamamoto K., Yokota M., Kato N., et al.
  • Journal Title: Hum Mol Genet Volume: 24 Pages: 1791-1800
  • DOI: 10.1093/hmg/ddu583
  • Peer Reviewed
• [Journal Article] A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese (2015)
  • Author(s): Hirokawa, M., Morita H., Tajima T., Takahashi A., Ashikawa K., Miya F., Shigemizu D., Ozaki K., Sakata Y., Nakatani D., Suna S., Imai Y., Tanaka T., Tsunoda T., Matsuda K., Kadowaki T., Nakamura Y., Nagai R., Komuro I. and Kubo M.
  • Journal Title: Eur J Hum Genet Volume: 23 Pages: 374-380
  • DOI: 10.1038/ejhg.2014.110
  • Peer Reviewed
• [Journal Article] Low FOXA1 expression predicts good response to neo-adjuvant chemotherapy resulting in good outcomes for luminal HER2-negative breast cancer cases (2015)
  • Author(s): Horimoto, Y., Arakawa A., Harada-Shoji N., Sonoue H., Yoshida Y., Himuro T., Igari F., Tokuda E., Mamat O., Tanabe M., Hino O. and Saito M.
  • Journal Title: Br J Cancer Volume: 112 Pages: 345-351
  • DOI: 10.1038/bjc.2014.595
  • Peer Reviewed
• [Journal Article] Genome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians (2015)
  • Author(s): Hwang, J.Y., Sim X., Wu Y., Liang J., Tabara Y., Hu C., Hara K., Takeuchi F., Ong R.T., Ohkubo T., Kim Y.J., Zhang R., Yamauchi T., Katsuya T., Umemura S., Maeda S., Kita Y., Takashima N., Osawa H., Kato N., et al.
  • Journal Title: Diabetes Volume: 64 Pages: 291-298
  • DOI: 10.2337/db14-0563
  • Peer Reviewed
• [Journal Article] Circulating Pigment Epithelium-derived Factor (PEDF) Is Associated with Pathological Grade of Prostate Cancer (2015)
  • Author(s): Ide, H., Yamagishi S., Lu Y., Sakamaki K., Nakajima A., Horiuchi A., Kitamura K., Hisasue S., Muto S., Yamaguchi R. and Horie S.
  • Journal Title: Anticancer Res Volume: 35 Pages: 1703-1708
  • Peer Reviewed
• [Journal Article] B-RAF mutation and accumulated gene methylation in aberrant crypt foci (ACF), sessile serrated adenoma/polyp (SSA/P) and cancer in SSA/P (2015)
  • Author(s): Inoue, A., Okamoto K., Fujino Y., Nakagawa T., Muguruma N., Sannomiya K., Mitsui Y., Takaoka T., Kitamura S., Miyamoto H., Okahisa T., Fujimori T., Imoto I. and Takayama T.
  • Journal Title: Br J Cancer Volume: 112 Pages: 403-412
  • DOI: 10.1038/bjc.2014.545
  • Peer Reviewed
• [Journal Article] Establishment of Tsc2-deficient rat embryonic stem cells (2015)
  • Author(s): Ito, Y., Kawano H., Kanai F., Nakamura E., Tada N., Takai S., Horie S., Arai H., Kobayashi T. and Hino O.
  • Journal Title: Int J Oncol Volume: 46 Pages: 1944-1952
  • DOI: 10.3892/ijo.2015.2913
  • Peer Reviewed
• [Journal Article] Comparison of plasma levels of nutrient-related biomarkers among Japanese populations in Tokyo, Japan, Sao Paulo, Brazil, and Hawaii, USA (2015)
  • Author(s): Iwasaki, M., Franke A.A., Hamada G.S., Miyajima N.T., Sharma S., Ishihara J., Takachi R., Tsugane S. and Le Marchand L.
  • Journal Title: Eur J Cancer Prev Volume: 24 Pages: 155-161
  • DOI: 10.1097/CEJ.0000000000000136
  • Peer Reviewed
• [Journal Article] Comparison of plasma levels of obesity-related biomarkers among Japanese populations in Tokyo, Japan, Sao Paulo, Brazil, and Hawaii, USA (2015)
  • Author(s): Iwasaki, M., Le Marchand L., Franke A.A., Hamada G.S., Miyajima N.T., Sharma S., Yamaji T. and Tsugane S.
  • Journal Title: Eur J Cancer Prev
  • DOI: 10.1097/CEJ.0000000000000123
  • Description: Epub ahead of print
  • Peer Reviewed
• [Journal Article] EVpedia : a community web portal for extracellular vesicles research (2015)
  • Author(s): Kim, D.K., Lee J., Kim S.R., Choi D.S., Yoon Y.J., Kim J.H., Go G., Nhung D., Hong K., Jang S.C., Kim S.H., Park K.S., Kim O.Y., Park H.T., Seo J.H., Aikawa E., Baj-Krzyworzeka M., van Balkom B.W., Tahara H., Youn H., et al.
  • Journal Title: Bioinformatics Volume: 31 Pages: 933-939
  • DOI: 10.1093/bioinformatics/btu741
  • Peer Reviewed
• [Journal Article] Cytological Features of a Variant NUT Midline Carcinoma of the Lung Harboring the NSD3-NUT Fusion Gene : A Case Report and Literature Review (2015)
  • Author(s): Kuroda, S., Suzuki S., Kurita A., Muraki M., Aoshima Y., Tanioka F. and Sugimura H.
  • Journal Title: Case Rep Pathol Volume: 2015 Pages: 572951
  • DOI: 10.1155/2015/572951
  • Peer Reviewed
• [Journal Article] Genome-wide association study identified SNP on 15q24 associated with bladder cancer risk in Japanese population (2015)
  • Author(s): Matsuda, K., Takahashi A., Obara W., Nasu Y., Inoue K., Tamura K., Yamasaki I., Naya Y., Tanikawa C., Namiki M., Tomita Y., Nishiyama H., Kohri K., Deguchi T., Nakagawa M., Yokoyama M., Miki T., Kumon H., Fujioka T., Kubo M., et al.
  • Journal Title: Hum Mol Genet Volume: 24 Pages: 1177-1184
  • DOI: 10.1093/hmg/ddu512
  • Peer Reviewed
• [Journal Article] Serologically Determined Gastric Mucosal Condition Is a Predictive Factor for Osteoporosis in Japanese Men (2015)
  • Author(s): Mizuno, S., Matsui D., Watanabe I., Ozaki E., Kuriyama N. and Watanabe Y.
  • Journal Title: Dig Dis Sci
  • DOI: 10.1007/s10620-015-3576-1
  • Description: Epub ahead of print
  • Peer Reviewed
• [Journal Article] Validity of the food frequency questionnaire in a population with high alcohol consumption in Japan (2015)
  • Author(s): Nakahata, T.N., Takada N.A., Imaeda N., Goto C., Kuwabara H.K., Niimura H., Arai H., Yoshita Y. and Takezaki T.K.
  • Journal Title: Asia Pac J Clin Nutr
  • Description: in press
  • Peer Reviewed
• [Journal Article] Dietary Patterns and Serum Gamma-Glutamyl Transferase in Japanese Men and Women (2015)
  • Author(s): Nanri, H., Hara M., Nishida Y., Shimanoe C., Nakamura K., Higaki Y., Imaizumi T., Taguchi N., Sakamoto T., Horita M., Shinchi K., Kokaze A. and Tanaka K.
  • Journal Title: J Epidemiol
  • DOI: 10.2188/jea.JE20140158
  • Description: in press
  • Peer Reviewed
• [Journal Article] CD44-expressing undifferentiated carcinoma with rhabdoid features of the pancreas : Molecular analysis of aggressive invasion and metastasis (2015)
  • Author(s): Ohmoto, T., Yoshitani N., Nishitsuji K., Takayama T., Yanagisawa Y., Takeya M. and Sakashita N.
  • Journal Title: Pathol Int
  • DOI: 10.1111/pin.12283
  • Description: Epub ahead of print
  • Peer Reviewed
• [Journal Article] Peretinoin after curative therapy of hepatitis C-related hepatocellular carcinoma : a randomized double-blind placebo-controlled study (2015)
  • Author(s): Okita, K., Izumi N., Matsui O., Tanaka K., Kaneko S., Moriwaki H., Ikeda K., Osaki Y., Numata K., Nakachi K., Kokudo N., Imanaka K., Nishiguchi S., Okusaka T., Nishigaki Y., Shiomi S., Kudo M., Ido K., Karino Y., Hayashi N., et al.
  • Journal Title: J Gastroenterol Volume: 50 Pages: 191-202
  • DOI: 10.1007/s00535-014-0956-9
  • Peer Reviewed
• [Journal Article] Cotyledonoid dissecting leiomyoma of the uterus : report of two cases (2015)
  • Author(s): Saeki, H., Suzuki C., Yamasaki S., Hashizume A., Izumi H., Suzuki F., Ishi K., Nojima M. and Hino O.
  • Journal Title: Arch Gynecol Obstet Volume: 291 Pages: 357-361
  • DOI: 10.1007/s00404-014-3406-2
  • Peer Reviewed
• [Journal Article] Association between endometriosis and the interleukin 1A (IL1A) locus (2015)
  • Author(s): Sapkota, Y., Low S.K., Attia J., Gordon S.D., Henders A.K., Holliday E.G., MacGregor S., Martin N.G., McEvoy M., Morris A.P., Takahashi A., Scott R.J., Kubo M., Zondervan K.T., Montgomery G.W. and Nyholt D.R.
  • Journal Title: Hum Reprod Volume: 30 Pages: 239-248
  • DOI: 10.1093/humrep/deu267
  • Peer Reviewed
• [Journal Article] Werner Syndrome-specific induced pluripotent stem cells : recovery of telomere function by reprogramming (2015)
  • Author(s): Shimamoto, A., Yokote K. and Tahara H.
  • Journal Title: Front Genet Volume: 6 Pages: 10
  • DOI: 10.3389/fgene.2015.00010
  • Peer Reviewed
• [Journal Article] Perceived stress and coping strategies in relation to body mass index : cross-sectional study of 12,045 Japanese men and women (2015)
  • Author(s): Shimanoe, C., Hara M., Nishida Y., Nanri H., Otsuka Y., Nakamura K., Higaki Y., Imaizumi T., Taguchi N., Sakamoto T., Horita M., Shinchi K. and Tanaka K.
  • Journal Title: PLoS One Volume: 10 Pages: e0118105
  • DOI: 10.1371/journal.pone.0118105
  • Peer Reviewed
• [Journal Article] The oncological outcome and validation of Japan Cancer of the Prostate Risk Assessment score among men treated with primary androgen-deprivation therapy (2015)
  • Author(s): Shiota, M., Yokomizo A., Takeuchi A., Imada K., Kiyoshima K., Inokuchi J., Tatsugami K. and Naito S.
  • Journal Title: J Cancer Res Clin Oncol Volume: 141 Pages: 495-503
  • DOI: 10.1007/s00432-014-1828-7
  • Peer Reviewed
• [Journal Article] Associations between polymorphisms of interleukin-6 and related cytokine genes and serum liver damage markers : a cross-sectional study in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study (2015)
  • Author(s): Sugimoto, Y., Wakai K., Nakagawa H., Suma S., Sasakabe T., Sakamoto T., Takashima N., Suzuki S., Ogawa S., Ohnaka K., Kuriyama N., Arisawa K., Mikami H., Kubo M., Hosono S., Hamajima N., Tanaka H. and J-Micc Study Group
  • Journal Title: Gene Volume: 557 Pages: 158-162
  • DOI: 10.1016/j.gene.2014.12.025
  • Peer Reviewed
• [Journal Article] Rheb actvation disrupts spine synapse formation through accumulation of syntenin in tuberous sclerosis complex (2015)
  • Author(s): Sugiura H., Y.S., Katsurabayashi S., Kawano H., Endo K., Takasaki K., Iwasaki K., Ichikawa M., Kobayashi T., Hino O. and Yamagata K.
  • Journal Title: Nature Communications Volume: 6 Pages: 6842
  • DOI: 10.1038/ncomms7842
  • Peer Reviewed
• [Journal Article] Urethral toxicity after LDR brachytherapy : experience in Japan (2015)
  • Author(s): Tanaka, N., Asakawa I., Hasegawa M. and Fujimoto K.
  • Journal Title: Brachytherapy Volume: 14 Pages: 131-135
  • DOI: 10.1016/j.brachy.2014.09.009
  • Peer Reviewed
• [Journal Article] A potential function for neuronal exosomes : sequestering intracerebral amyloid-beta peptide (2015)
  • Author(s): Yuyama, K. Sun H., Usuki S. Sakai S. Hanamatsu H., Mioka T. Kimura N. Okada N. Tahara H. Furukawa J. Fujitani N. Shinohara Y. and Igarashi Y.
  • Journal Title: FEBS Lett Volume: 589 Pages: 84-88
  • DOI: 10.1016/j.febslet.2014.11.027
  • Peer Reviewed
• [Journal Article] Clinical outcomes of a novel therapeutic vaccine with Tax peptide-pulsed dendritic cells for adult T cell leukaemia/lymphoma in a pilot study. (2015)
  • Author(s): Suehiro, Y., Hasegawa, A., Iino, T., Sasada, A., Watanabe, N., Matsuoka, M., Takamori, A., Tanosaki, R., Utsunomiya, A., Choi, I., Fukuda, T., Miura, O., Takaishi, S., Teshima, T., Akashi, K., Kannagi, M., Uike, N., Okamura, J.
  • Journal Title: British journal of haematology
  • DOI: 10.1111/bjh.13302
  • Description: 印刷中
  • Peer Reviewed
• [Journal Article] Involvement of double-stranded RNA-dependent protein kinase and antisenseviral RNA in the constitutive NFkappaB activation in adult T-cell leukemia/lymphoma cells (2015)
  • Author(s): Kinpara, S., Ito, S., Takahata, T., Saitoh, Y., Hasegawa, A., Kijiyama, M., Utsunomiya, A., Masuda, M., Miyazaki, Y., Matsuoka, M., Nakamura, M., Yamaoka, S., Masuda, T., Kannagi, M.
  • Journal Title: Leukemia
  • DOI: 10.1038/leu.2015.1
  • Description: 印刷中
  • Peer Reviewed
• [Journal Article] Fatal reactivation of hepatitis B virus infection in a patient with adult T-cell leukemia-lymphoma receiving the anti-CC chemokine receptor 4 antibody mogamulizumab (2015)
  • Author(s): Ifuku, H., Kusumoto, S., Tanaka, Y., Totani, H., Ishida, T., Okada, M., Murakami, S., Mizokami, M., Ueda, R. & lida, S.
  • Journal Title: Hepatology research : the official journal of the Japan Society of Hepatology
  • DOI: 10.1111/hepr.12513
  • Description: 印刷中
  • Peer Reviewed
• [Journal Article] Dose-intensified chemotherapy alone or in combination with mogamulizumab in newly diagnosed aggressive adult T-cell leukaemia-lymphoma : a randomized phase II study (2015)
  • Author(s): Ishida, T., Jo, T., Takemoto, S., Suzushima, H., Uozumi, K., Yamamoto, K., Uike, N., Saburi, Y., Nosaka, K., Utsunomiya, A., Tobinai, K., Fujiwara, H., Ishitsuka, K., Yoshida, S., Taira, N., Moriuchi, Y., Imada, K., Miyamoto, T., Akinaga, S., Tomonaga, M. & Ueda, R.
  • Journal Title: British journal of haematology
  • DOI: 10.1111/bjh.13338
  • Description: 印刷中
  • Peer Reviewed
• [Journal Article] Prognostic significance of tryptophan catabolism in adult T-cell leukemia/lymphoma (2015)
  • Author(s): Masaki, A., Ishida, T., Maeda, Y., Suzuki, S., Ito, A., Takino, H., Ogura, H., Totani, H., Yoshida, T., Kinoshita, S., Narita, T., Ri, M., Kusumoto, S., Inagaki, A., Komatsu, H., Niimi, A., Ueda, R., Utsunomiya, A., Inagaki, H. & Iida, S.
  • Journal Title: Clinical cancer research : an official journal of the American Association for Cancer Research
  • DOI: 10.1158/1078-0432.CCR-14-2275
  • Description: 印刷中
  • Peer Reviewed
• [Journal Article] CD30-positive primary bone marrow lymphoma mimicking Hodgkin lymphoma (2015)
  • Author(s): Suzuki T, Kusumoto S, Masaki A, Ishida T, Inagaki H, Iida S, Mori F
  • Journal Title: Int J Hematol Volume: 101 Issue: 2 Pages: 109-11
  • DOI: 10.1007/s12185-014-1714-8
  • Peer Reviewed
• [Journal Article] Reactivation of hepatitis B virus (HBV) infection in adult T-cell leukemia-lymphoma patients with resolved HBV infection following systemic chemotherapy (2015)
  • Author(s): Totani, H., Kusumoto, S., Ishida, T., Masuda, A., Yoshida, T., Ito, A., Ri, M., Komatsu, H., Murakami, S., Mizokami, M., Ueda, R., Niimi, A., Inagaki, H., Tanaka, Y. & Iida, S.
  • Journal Title: International journal of hematology Volume: 101 Pages: 398-404
  • DOI: 10.1007/s12185-015-1750-z
  • Peer Reviewed
• [Journal Article] TCFl and LEFl act as T-cell intrinsic HTLV-1 antagonists by targeting Tax (2015)
  • Author(s): Ma G, Yasunaga J-I, Akari H, Matsuoka M
  • Journal Title: Proc. Natl. Acad. Sci. U.S.A. Volume: 112 Pages: 2216-2221
  • DOI: 10.1073/pnas.1419198112
  • Peer Reviewed
• [Journal Article] Human T-cell leukemia virus type 1 Tax oncoprotein represses the expression of the BCL11B tumor suppressor in T-cells (2015)
  • Author(s): Takachi T, Takahashi M, Takahashi-Yoshita M, Higuchi M, Obata M, Mishima Y, Okuda S, Tanaka Y, Matsuoka M, Saitoh A, Green P, Fujii M
  • Journal Title: Cancer Sci
  • DOI: 10.1111/cas.12618
  • Description: in press
  • Peer Reviewed
• [Journal Article] Re-evaluation of screening of plasma positive for human T-cell leukemia virus type 1 using a luciferase immunoprecipitation system in blood donors (2015)
  • Author(s): Furuta RA, Ma G, Matsuoka M, Otani S, Matsukura H, Hirayama F
  • Journal Title: Transfusion
  • DOI: 10.1111/trf.12911
  • Description: in press
  • Peer Reviewed
• [Journal Article] Visualization of HTLV-1-specific cytotoxic T lymphocytes in the spinal cords of patients with HTLV-1-associated myelopathy/tropical spastic paraparesis (2015)
  • Author(s): Matsuura E, Kubota R, Tanaka Y, Takashima H, Izumo S
  • Journal Title: J Neuropathol Exp Neurol Volume: 74 Issue: 1 Pages: 2-14
  • DOI: 10.1097/NEN.0000000000000141
  • Peer Reviewed
• [Journal Article] Separate cellular localizations of human T-lymphotropic virus 1 (HTLV-1) Env and glucose transporter type 1 (GLUT1) are required for HTLV-1 Env-mediated fusion and infection (2015)
  • Author(s): Maeda Y, Terasawa H, Tanaka Y, Mitsuura C, Nakashima K, Yusa K, Harada S
  • Journal Title: J Virol Volume: 89 Issue: 1 Pages: 502-11
  • DOI: 10.1128/JVI.02686-14
  • Peer Reviewed
• [Journal Article] Mogamulizumab, an anti-CCR4 antibody, targets human T-lymphotropic virus type 1-infected CD8+ and CD4+ T cells to treat associated myelopathy (2015)
  • Author(s): Yamauchi J, Coler-Reilly A, Sato T, Araya N, Yagishita N, Ando H, Kunitomo Y, Takahashi K, Tanaka Y, Shibagaki Y, Nishioka K, Nakajima T, Hasegawa Y, Utsunomiya A, Kimura K, Yamano Y
  • Journal Title: J Infect Dis Volume: 211 Issue: 2 Pages: 238-48
  • DOI: 10.1093/infdis/jiu438
  • Peer Reviewed
• [Journal Article] Advanced HTLV-1 carriers and early-stage indolent ATLs are indistinguishable based on CADM1 positivity in flow cytometry (2015)
  • Author(s): Kobayashi S, Watanabe E, Ishigaki T, Ohno N, Yuji K, Nakano K, Yamochi T, Watanabe N, Tojo A, Watanabe T, Uchimaru K
  • Journal Title: Cancer Sci
  • DOI: 10.1111/cas.12639
  • Description: Epub ahead of print
  • Peer Reviewed
• [Journal Article] Identification of TL-Oml, an ATL Cell Line, as a Reference Material for Human T-Lymphotropic Virus 1 Quantitative PCR (2015)
  • Author(s): Kuramitsu M, Okuma K, Yamagishi M, Yamochi T, Firouzi S, Momose H, Mizukami T, Takizawa K, Araki K, Sugamura K, Yamaguchi K, Watanabe T, Hamaguchi I
  • Journal Title: J Clin Microbiol Volume: 53 Issue: 2 Pages: 587-596
  • DOI: 10.1128/JCM.02254-14
  • Peer Reviewed
• [Journal Article] Epigenetic Heterogeneity in HIV-1 Latency Establishment (2015)
  • Author(s): Matsuda Y, Kobayashi-Ishihara M, Fujikawa D, Ishida T, Watanabe T, Yamagishi M
  • Journal Title: Sci Rep Volume: 5 Pages: 7701
  • DOI: 10.1038/srep07701
  • Peer Reviewed
• [Journal Article] SMK-17, a MEK1/2-specific inhibitor, selectively induces apoptosis in β-catenin-mutated tumors. (2015)
  • Author(s): Kiga M, Nakayama A, Shikata Y, Sasazawa Y, Murakami R, Nakanishi T, Tashiro E, Imoto M.
  • Journal Title: Sci Rep. Volume: 5 Pages: 8155
  • DOI: 10.1038/srep08155
  • Peer Reviewed
• [Journal Article] Basal expression of insulin-like growth factor l receptor determines intrinsic resistance of cancer cells to a phosphatidylinositol 3-kinase inhibitor ZSTK474 (2015)
  • Author(s): Isoyama S, Kajiwara G, Tamaki N, Okamura M, Yoshimi H, Nakamura N, Kawamura K, Nishimura Y, Namatame N, Yamori T, Dan S
  • Journal Title: Cancer Sci Volume: 106 Issue: 2 Pages: 171-178
  • DOI: 10.1111/cas.12582
  • Peer Reviewed
• [Journal Article] Design, synthesis and structure-activity relationships of 1-ethylpyrazole-3-carboxamide as novel HIF-1 inhibitors (2015)
  • Author(s): Yasuda Y, Arakawa T, Nawata Y, Shimada S, Oishi S, Fujii N, Nishimura S, Hattori A, Kakeya H
  • Journal Title: Bioorg. Med. Chem. Volume: 23 Pages: 1776-1787
  • DOI: 10.1016/j.bmc.2015.02.038
  • Peer Reviewed
• [Journal Article] Association of microRNA-31-5p with clinical efficacy of anti-EGFR therapy in patients with metastatic colorectal cancer (2015)
  • Author(s): Igarashi H, Kurihara H, Mitsuhashi K, Ito M, Okuda H, Kanno S, Naito T, Yoshii S, Takahashi H, Kusumi T, Hasegawa T, Sukawa Y, Adachi Y, Okita K, Hirata K, Imamura Y, Baba Y, Imai K, Suzuki H, Yamamoto H, Nosho K, Shinomura Y
  • Journal Title: Ann Surg Oncol
  • DOI: 10.1245/s10434-014-4264-7
  • Description: Epub ahead of print
  • Peer Reviewed
• [Journal Article] Mesenchymal stem cells cancel azoxymethane-induced tumor initiation (2014)
  • Author(s): Nasuno M, Arimura Y, Nagaishi K, Isshiki H, Onodera K, Nakagaki S, Watanabe S, Idogawa M, Yamashita K, Naishiro Y, Adachi Y, Suzuki H, Fujimiya M, Imai K, Shinomura Y
  • Journal Title: STEM CELLS Volume: 32 Issue: 4 Pages: 913-25
  • DOI: 10.1002/stem.1594
  • Peer Reviewed
• [Journal Article] MicroRNA-31 expression in relation to BRAF mutation, CpG island methylation and colorectal continuum in serrated lesions (2014)
  • Author(s): Ito M, Mitsuhashi K, Igarashi H, Nosho K, Naito T, Yoshii S, Takahashi H, Fujita M, Sukawa Y, Yamamoto E, Takahashi T, Adachi Y, Nojima M, Sasaki Y, Tokino T, Baba Y, Maruyama R, Suzuki H, Imai K, Yamamoto H, Shinomura Y
  • Journal Title: Int J Cancer Volume: 135 Issue: 11 Pages: 2507-15
  • DOI: 10.1002/ijc.28920
  • Peer Reviewed
• [Journal Article] The effect of IGF-I receptor blockade for human esophageal squamous cell carcinoma and adenocarcinoma (2014)
  • Author(s): Adachi Y, Ohashi H, Imsumran A, Yamamoto H, Matsunaga Y, Taniguchi H, Nosho K, Suzuki H, Sasaki Y, Arimura Y, Carbone DP, Imai K, Shinomura Y
  • Journal Title: Tumor Biol Volume: 35 Issue: 2 Pages: 973-85
  • DOI: 10.1007/s13277-013-1131-2
  • Peer Reviewed
• [Journal Article] Analysis of DNA methylation in bowel lavage fluid for detection of colorectal cancer (2014)
  • Author(s): Harada T, Yamamoto E, Yamano H, Nojima M, Maruyama R, Kumegawa K, Ashida M, Yoshikawa K, Kimura T, Harada E, Takagi R, Tanaka Y, Aoki H, Nishizono M, Nakaoka M, Tuyada A, Niinuma T, Kai M, Shimoda K, Shinomura Y, Sugai T, Imai K, Suzuki H
  • Journal Title: Cancer Prevention Research (Philadelphia, Pa.) Volume: 7 Issue: 10 Pages: 1002-10
  • DOI: 10.1158/1940-6207.CAPR-14-0162
  • Peer Reviewed
• [Journal Article] Overview and Future prospect of “Promotion plan for the platform of human resource development for cancer” (2014)
  • Author(s): Imai K.
  • Journal Title: Juntendo Medical Journal Volume: 60 Issue: 3 Pages: 234-237
  • Peer Reviewed
• [Journal Article] IGF2 differentially methylated region hypomethylation in relation to pathological and molecular features of serrated lesions (2014)
  • Author(s): Naito T, Nosho K, Ito M, Igarashi H, Mitsuhashi K, Yoshii S, Aoki H, Nomura M, Sukawa Y, Yamamoto E, Adachi Y, Takahashi H, Hosokawa M, Fujita M, Takenouchi T, Maruyama R, Suzuki H, Baba Y, Imai K, Yamamoto H, Ogino S, Shinomura Y
  • Journal Title: World J Gastroenterol Volume: 20 Issue: 29 Pages: 10050-61
  • DOI: 10.3748/wjg.v20.i29.10050
  • Peer Reviewed
• [Journal Article] DNA synthesis inhibitors for the treatment of gastrointestinal cancer (2014)
  • Author(s): Yasui H, Tsurita G, Imai K
  • Journal Title: Expert Opin Pharmacother Volume: 15 Issue: 16 Pages: 2361-72
  • DOI: 10.1517/14656566.2014.958074
  • Peer Reviewed
• [Journal Article] The Use of Bone Marrow Stromal Cells (Bone Marrow-Derived Multipotent Mesenchymal Stromal Cells) for Alveolar Bone Tissue Engineering : Basic Science to Clinical Translation (2014)
  • Author(s): Kagami H, Agata H, Inoue M, Asahina I, Tojo A, Yamashita N, Imai K
  • Journal Title: Tissue Engineering Part B : Reviews Volume: 20 Issue: 3 Pages: 229-232
  • DOI: 10.1089/ten.TEB.2013.0578
  • Peer Reviewed
• [Journal Article] Association of microRNA-31-5p with clinical efficacy of anti-EGFR therapy in patients with metastatic colorectal cancer (2014)
  • Author(s): Igarashi H, Kurihara H, Mitsuhashi K, Ito M, Okuda H, Kanno S, Naito T, Yoshii S, Takahashi H, Kusumi T, Hasegawa T, Sukawa Y, Adachi Y, Okita K, Hirata K, Imamura Y, Baba Y, Imai K, Suzuki H, Yamamoto H, Nosho K, Shinomura Y
  • Journal Title: Annals of Surgical Oncology
  • Description: Epub ahead of print
  • Peer Reviewed
• [Journal Article] 総説 橋渡し研究の展開と我が国の医療 (2014)
  • Author(s): 今井浩三
  • Journal Title: 東京都病院薬剤師会雑誌 Volume: 63 Issue: 2 Pages: 5-8
  • Peer Reviewed
• [Journal Article] 人口動態に基づいた日本医療の未来予測-高齢多死社会の到来, 特集「超高齢者に対する外科治療の問題点」 (2014)
  • Author(s): 湯地晃一郎, 井元清哉, 山口類, 宮野悟, 上昌広, 今井浩三
  • Journal Title: 南江堂臨床雑誌「外科」 Volume: 76 Issue: 5 Pages: 457-463
  • Peer Reviewed
• [Journal Article] 大規模コホートを用いた大腸癌のノンコーディングRNA発現異常と生活習慣の分子疫学的解析 (2014)
  • Author(s): 能正勝彦, 五十嵐央祥, 伊藤美樹, 三橋慧, 栗原弘義, 菅野伸一, 内藤崇史, 須河安恭敬, 松永康孝, 足立靖, 野島正寛, 今井浩三, 丸山玲緒, 鈴木拓, 山本博幸, 篠村恭久
  • Journal Title: 日本癌病態治療研究会誌 Volume: 20 Issue: 1 Pages: 60-63
  • Peer Reviewed
• [Journal Article] がんエピゲノム異常を理解し、応用し、そして制御するために (2014)
  • Author(s): 鈴木拓, 今井浩三
  • Journal Title: 実験医学 Volume: 32 Issue: 19 Pages: 3024-3029
  • Peer Reviewed
• [Journal Article] Generation and analysis of serine protease inhibitor Kazal type 3-cre driver mice (2014)
  • Author(s): Sakata, K., Ohmuraya, M., Araki, K., Suzuki, C., Ida, S., Hashimoto, D., Wang, J., Uchiyama, Y., Baba, H. and Yamamura, K.
  • Journal Title: Exp. Anim. Volume: 63 Pages: 45-53
  • Peer Reviewed
• [Journal Article] Autophagy regulation in the pancreatic acinar cells is independent of epidermal growth factor receptor signaling (2014)
  • Author(s): Ozaki, N., Fukuchi, Y., Tomiyoshi, S., Ueharal, H., Ida, S., Wang, J., Kimi Araki, K., Sibilia, M., Baba, H., Yamamura, K. and Ohmuraya, M
  • Journal Title: Biochem. Biophysic. Res. Comm. Volume: 446 Pages: 224-230
  • DOI: 10.1016/j.bbrc.2014.02.111
  • Peer Reviewed
• [Journal Article] Low serum level of high-sensitivity C-reactive protein in a Japanese subject with MODY3 (2014)
  • Author(s): Ohki T, Utsu Y, Morita S, Karim M.F., Sato Y, Yoshizawa T, Yamamura K, Yamada K, Kasayama S, Yamagata K
  • Journal Title: J. Diabetes Invest Volume: 5 Pages: 513-516
  • DOI: 10.1111/jdi.12237
  • Peer Reviewed
• [Journal Article] Genetic analysis of the role of Alx4 in the coordination of lower body and external genitalia formation (2014)
  • Author(s): Matsumaru, D., Haraguchi, R., Moon, A.M., Satoh, Y., Nakagata, N., Yamamura, K., Takahashi, N., Kitazawa, S. and Yamada, G.
  • Journal Title: Eur. J. Human Genet Volume: 22 Pages: 350-357
  • DOI: 10.1038/ejhg.2013.160
  • Peer Reviewed
• [Journal Article] mTORCl controls the cell cycle of the earliest T-lineage-committed cells and its inactivation eradicates acute Iymphoblastic T-cell leukemia in mice (2014)
  • Author(s): Hoshii, T., Kasada, A., Hatakeyama, N., Ohtani, M., Tadokoro, Y., Naka, K., Ikenoue, T., Ikawa, T., Kawamoto, H., Araki, K., Yamamura, K., Matsuda, S. and Hirao, A.
  • Journal Title: Proc. Natl. Acad. Sci. USA Volume: 111 Pages: 3805-3810
  • DOI: 10.1073/pnas.1320265111
  • Peer Reviewed
• [Journal Article] Circulating AIM prevents hepatocellular carcinoma through complement activation (2014)
  • Author(s): Maehara, N., Arai, S., Mori, M., Iwamura, Y., Kurokawa, J., Kai, T., Kusunoki, S., Taniguchi, K., Ikeda, K., Ohara, O., Yamamura, K. and Miyazaki, T.
  • Journal Title: Cell Report Volume: 9 Pages: 1-14
  • DOI: 10.1016/j.celrep.2014.08.058
  • Peer Reviewed
• [Journal Article] Disruption of dystonin protein containing actin-binding domain cause dystonia musculorum in mice (2014)
  • Author(s): Horie, M., Watanabe, K., Bepari, A.K., Nashimoto, J., Araki, K., Sano, H., Chiken, S., Nambu, A., Ono, K., Ikenaka, K., Kakita, A., Yamamura, K. and Takebayashi, H.
  • Journal Title: Eur. J. Neurocsi Volume: 40 Pages: 3458-3471
  • DOI: 10.1111/ejn.12711
  • Peer Reviewed
• [Journal Article] Circulating AIM as an indicator of liver damage and hepatocellular carcinoma in humans (2014)
  • Author(s): Yamazaki, T., Mori, M., Arai, S., Tateishi, R., Abe, M., Ban, M., Nishijima, A., Maeda, M., Asano, T., Kai, T., Izumino, K., Takahashi, J., Aoyama, K., Harada, S., Takebayashi, T., Gunji, T, Ohnishi, S., Seto, S., Yoshida, Y., Hiasa, Y., Koike, K., Yamamura, K., Inoue, K. & Miyazaki, T.
  • Journal Title: Plos One Volume: 9 Pages: e109123
  • DOI: 10.1371/journal.pone.0109123
  • Peer Reviewed
• [Journal Article] Database for exchangeable gene trap clones : Pathway and gene ontology analysis of exchangeable genetrap clone mouse lines (2014)
  • Author(s): Araki, M., Nakahara, M., Muta, M., Itou, M., Yanai, C., Yamazoe, F., Miyake, M., Morita, A., Araki, M., Okamoto, Y., Nakagata, M., Yoshinobu, K., Yamamura, K. and Araki, K.
  • Journal Title: Develop. Growth Differ Volume: 56 Pages: 161-174
  • DOI: 10.1111/dgd.12116
  • Peer Reviewed
• [Journal Article] Screening Methods to Identify TALEN-Mediated Knockout Mice (2014)
  • Author(s): Nakagawa, Y., Yamamoto, T., Suzuki, K., Araki, K., Takeda, N., Ohmuraya, M. and Sakuma, T.
  • Journal Title: Exp. Anim. Volume: 63 Pages: 79-84
  • Peer Reviewed
• [Journal Article] Role of blood ribosomal protein S19 in coagulum resorption : a study using Gln137Glu-ribosomal protein S19 gene knock-in mouse (2014)
  • Author(s): Chen, J., Fujino, R., Zhao, R., Semba, U., Araki, K. and Yamamoto, T.
  • Journal Title: Pathol. Int. Volume: 64 Pages: 543-550
  • DOI: 10.1111/pin.12208
  • Peer Reviewed
• [Journal Article] Conformational Change in Transfer RNA Is an Early Indicator of Acute Cellular Damage (2014)
  • Author(s): Mishima, E., Inoue, C., Saigusa, D., Inoue, R., Ito, K., Suzuki, Y., Jinno, D., Tsukui, Y., Akamatsu, Y., Araki, M., Araki, K., Shimizu, R., Shinke, H., Suzuki, T., Takeuchi, Y., Shima, H., Akiyama, Y., Yamamura, K., et al.
  • Journal Title: J. Am. Soc. Nephrol Volume: 25 Pages: 2316-2326
  • DOI: 10.1681/ASN.2013091001
  • Peer Reviewed
• [Journal Article] Impaired degradation of WNK1 and WNK4 kinases causes PHAII in mutant KLHL3 knock-in mice (2014)
  • Author(s): Susa, K, Sohara, E, Rai, T, Zeniya, M, Mori, Y, Mori, T, Chiga, M, Nomura, N, Nishida, H, Takahashi, D, Isobe, K, Inoue, Y, Takeishi, K, Takeda, N, Sasaki, S, Uchida, S
  • Journal Title: Hum Mol Genet Volume: 23 Pages: 5052-5060
  • DOI: 10.1093/hmg/ddu217
  • Peer Reviewed
• [Journal Article] Novel retinoblastoma mutation abrogating the interaction to E2F2/3, but not E2F1, led to selective suppression of thyroid tumors (2014)
  • Author(s): Toki, H., Inoue, M., Minowa, O., Motegi, H., Saiki, Y., Wakana, S., Masuya, H., Gondo, Y., Shiroishi, T., Yao, R. & Noda, T.
  • Journal Title: Cancer Sci Volume: 105 Pages: 1360-1368
  • DOI: 10.1111/cas.12495
  • Peer Reviewed
• [Journal Article] Deficiency of Transcription Factor Brn4 Disrupts Cochlear Gap Junction Plaques in a Model of DFN3 Non-Syndromic Deafness (2014)
  • Author(s): Kidokoro Y, Karasawa K, Minowa O, Sugitani Y., Noda T, Ikeda K, Kamiya K.
  • Journal Title: PLoS One Volume: 9 Issue: 9 Pages: e108216
  • DOI: 10.1371/journal.pone.0108216
  • Peer Reviewed
• [Journal Article] Assembly of the cochlear gap junction macromolecular complex requires connexin 26 (2014)
  • Author(s): Kamiya K, Yum SW, Kurebayashi N, Muraki M, Ogawa K, Karasawa K, Miwa A, Guo X, Gotoh S, Sugitani Y., Yamanaka H, Ito-Kawashima S, Iizuka T, Sakurai T, Noda T, Minowa O, Ikeda K.
  • Journal Title: J. Clin. Invest. Volume: 124 Issue: 4 Pages: 1598-1607
  • DOI: 10.1172/JCI67621
  • Peer Reviewed
• [Journal Article] Identification of genomic locus responsible for experimentally induced testicular teratoma 1 (ettl) on mouse Chr 18 (2014)
  • Author(s): Miyazaki, T., Ikeda, Y., Kubo, I., Suganuma, S., Fujita, N., Itakura, M., Hayashi, T., Takabayashi, S., Katoh, H., Ohira, Y., Sato, M., Noguchi, M., Tokumoto, T.
  • Journal Title: Mammalian Genome Volume: 25 Pages: 317-326
  • DOI: 10.1007/s00335-014-9529-8
  • Peer Reviewed
• [Journal Article] Contemporary techniques for freezing mouse spermatozoa (2014)
  • Author(s): Guan, M., Bogani D., Marschall, S., Raspa M., Takeo, T., Nakagata, N., Taft, R. and Fray, M.
  • Journal Title: Curr Protoc Mouse Biol Volume: 4 Issue: 3 Pages: 85-104
  • DOI: 10.1002/9780470942390.mo140065
  • Peer Reviewed
• [Journal Article] In vitro fertilization in mice using the MBCD-GSH protocol (2014)
  • Author(s): Guan, M., Bogani, D., Marschall, S., Raspa, M., Takeo, T., Nakagata, N. and Fray, M.
  • Journal Title: Curr Protoc Mouse Biol Volume: 4 Issue: 2 Pages: 67-83
  • DOI: 10.1002/9780470942390.mo140059
  • Peer Reviewed
• [Journal Article] Transporting mouse embryos and germplasm as frozen or unfrozen materials (2014)
  • Author(s): Kenyon, J., Guan, M., Bogani, D., Marschall, S., Raspa, M., Pickard, A., Takeo, T., Nakagata, N. and Fray, M.
  • Journal Title: Curr Protoc Mouse Biol Volume: 4 Issue: 2 Pages: 47-65
  • DOI: 10.1002/9780470942390.mo140064
  • Peer Reviewed
• [Journal Article] Conservation of mouse models through embryo freezing (2014)
  • Author(s): Guan, M, Bogani, D, Marschall, S, Raspa, M, Takeo, T, Nakagata, N, Fray, M
  • Journal Title: Curr Protoc Mouse Biol Volume: 4 Issue: 4 Pages: 205-227
  • DOI: 10.1002/9780470942390.mo140082
  • Peer Reviewed
• [Journal Article] Rescue in vitro fertilization method for legacy stock of frozen mouse sperm (2014)
  • Author(s): Nakagata, N, Takeo, T, Fukumoto, K, Haruguchi, Y, Kondo, T, Takeshita, Y, Nakamuta, Y, Umeno, T, Tsuchiyama, S
  • Journal Title: J Reprod Dev Volume: 60 Issue: 2 Pages: 168-171
  • Peer Reviewed
• [Journal Article] Application of oocyte cryopreservation technology in TALEN-mediated mouse genome editing (2014)
  • Author(s): Nakagawa, Y., Sakuma, T., Nakagata, N., Yamasaki, S., Takeda, N., Ohmuraya, M. and Yamamoto, T.
  • Journal Title: Exp Anim Volume: 63 Issue: 3 Pages: 349-355
  • Peer Reviewed
• [Journal Article] Histological detection of catalytic ferrous iron with the selective turn-on fluorescent probe RhoNox-1 in a Fenton reaction-based rat renal carcinogenesis model (2014)
  • Author(s): Mukaide, T, Hatori, Y, Misawa, N, Funahashi, S, Jiang, L, Hirayama, T, Nagasawa, H and Toyokuni, S
  • Journal Title: Free Radic Res Volume: 48 Pages: 990-995
  • DOI: 10.3109/10715762.2014.898844
  • Peer Reviewed
• [Journal Article] Connective tissue growth factor and β-catenin constitute an autocrine loop for activation in rat sarcomatoid mesothelioma (2014)
  • Author(s): Jiang, L, Yamashita, Y, Chew, SH, AKatsuka, S, Ukai, S, Wang, S, Nagai, H, Okazaki, Y, Takahashi, T and Toyokuni, S
  • Journal Title: J Pathol Volume: 233 Pages: 402-414
  • DOI: 10.1002/path.4377
  • Peer Reviewed
• [Journal Article] Iron and thiols as two major players in carcinogenesis : friends or foes? (2014)
  • Author(s): Toyokuni, S.
  • Journal Title: Front Pharmacol Volume: 5 Pages: 200
  • DOI: 10.3389/fphar.2014.00200
  • Peer Reviewed
• [Journal Article] Hsc70 contributes to cancer cell survival by preventing RablA degradation under stress conditions (2014)
  • Author(s): Tanaka, M, Mun, S, Harada, A, Ohkawa, Y, Inagaki, A, Sano, S, Takahashi, K, Izumi, Y, Osada-Oka, M, Wanibuchi, H, Yamagata, M, Yukimura, T, Miura, K, Shiota, M, Iwao, H
  • Journal Title: PLoS One Volume: 9 Pages: e96785
  • DOI: 10.1371/journal.pone.0096785
  • Peer Reviewed
• [Journal Article] Inhibitory effect of raphanobrassica on Helicobacter pylori-induced gastritis in Mongolian gerbils (2014)
  • Author(s): Yamada, T, Wei, M, Toyoda, T, Yamano, S, Wanibuchi, H
  • Journal Title: Food Chem Toxicol Volume: 70 Pages: 107-113
  • DOI: 10.1016/j.fct.2014.04.037
  • Peer Reviewed
• [Journal Article] Genotoxicity and subacute toxicity studies of a new astaxanthin-containing Phaffia rhodozyma extract (2014)
  • Author(s): Tago, Y, Fujii, T, Wada, J, Kato, M, Wei, M, Wanibuchi, H, Kitano, M
  • Journal Title: J Toxicol Sci Volume: 39 Pages: 373-382
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• [Journal Article] Vascular endothelial growth factor mRNA levels as a biomarker for short-term N-butyl-N-(4-hydroxybutyl) nitrosamine-induced rat bladder carcinogenesis bioassay (2014)
  • Author(s): Wakui, S, Mutou, T, Takahashi, H, Ikegami, M, Wanibuchi, H, Fukushima, S
  • Journal Title: J Appl Toxicol Volume: 35 Issue: 2 Pages: 181-190
  • DOI: 10.1002/jat.3021
  • Peer Reviewed
• [Journal Article] Valerian inhibits rat hepatocarcinogenesis by activating GABA(A) receptor-mediated signaling (2014)
  • Author(s): Kakehashi, A, Kato, A, Ishii, N, Wei, M, Morimura, K, Fukushima, S, Wanibuchi, H
  • Journal Title: PLoS One Volume: 9 Pages: e113610
  • DOI: 10.1371/journal.pone.0113610
  • Peer Reviewed
• [Journal Article] Establishment of neutralizing rat monoclonal antibodies for fibroblast growth factor-2 (2014)
  • Author(s): Tanaka, M, Yamaguchi, M, Shiota, M, Kawamoto, Y, Takahashi, K, Inagaki, A, Osada-Oka, M, Harada, A., Wanibuchi, H, Izumi, Y, Miura, K, Iwao, H, Ohkawa, Y
  • Journal Title: Monoclon Antib Immunodiagn Immunother Volume: 33 Pages: 261-269
  • DOI: 10.1089/mab.2013.0085
  • Peer Reviewed
• [Journal Article] Comparative proteomics analysis of gastric cancer stem cells (2014)
  • Author(s): Morisaki, T, Yashiro, M, Kakehashi, A, Inagaki, A, Kinoshita, H, Fukuoka, T, Kasashima, H, Masuda, G, Sakurai, K, Kubo, N, Muguruma, K, Ohira, M., Wanibuchi, H, Hirakawa, K
  • Journal Title: PLoS One Volume: 9 Pages: e110736
  • DOI: 10.1371/journal.pone.0110736
  • Peer Reviewed
• [Journal Article] Nanosized zinc oxide particles do not promote DHPN-induced lung carcinogenesis but cause reversible epithelial hyperplasia of terminal bronchioles (2014)
  • Author(s): Xu, J., Futakuchi, M., Alexander, D.B., Fukamachi, K., Numano, T., Suzui, M., Shimizu, H., Omori, T., Kanno, J., Hirose, A., and Tsuda, H
  • Journal Title: Archives of toxicology Volume: 88 Pages: 65-75
  • DOI: 10.1007/s00204-013-1086-5
  • Peer Reviewed
• [Journal Article] Size-and shape-dependent pleural translocation, deposition, fibrogenesis, and mesothelial proliferation by multiwalled carbon nanotubes (2014)
  • Author(s): Xu, J., Alexander, D.B., Futakuchi, M., Numano, T., Fukamachi, K., Suzui, M., Omori, T., Kanno, J., Hirose, A., and Tsuda, H
  • Journal Title: Cancer Sci Volume: 105 Pages: 763-769
  • DOI: 10.1111/cas.12437
  • Peer Reviewed
• [Journal Article] Comparative study of toxic effects of anatase and rutile type nanosized titanium dioxide particles in vivo and in vitro (2014)
  • Author(s): Numano, T., Xu, J., Futakuchi, M., Fukamachi, K., Alexander, D.B., Furukawa, F., Kanno, J., Hirose, A., Tsuda, H., and Suzui, M
  • Journal Title: Asian Pacific J Cancer Prev Volume: 15 Pages: 929-935
  • Peer Reviewed
• [Journal Article] Rat N-ERC/mesothelin as a marker for in vivo screening of drugs against pancreas cancer (2014)
  • Author(s): Fukamachi, K., Iigo, M., Hagiwara, Y., Shibata, K., Futakuchi, M., Alexander, D.B., Hino, O., Suzui, M., and Tsuda, H
  • Journal Title: Plos One Volume: 9 Pages: e111481
  • DOI: 10.1371/journal.pone.0111481
  • Peer Reviewed
• [Journal Article] Murine Herc6 plays a critical role in protein ISGylation in vivo and has an ISGylation independent function in seminal vesicles (2014)
  • Author(s): Arimoto, K.-i., Hishiki, T., Kiyonari, H., Abe, T., Cheng, C., Yan, M., Fan, J.-B., Futakuchi, M., Tsuda, H., Murakami, Y., Suzuki, H., Zhang, D.-E., and Shimotohno, K.
  • Journal Title: J. Interferon & Cytokine Res
  • DOI: 10.1089/jir.2014.0113
  • Peer Reviewed
• [Journal Article] Significance of the progesterone receptor and epidermal growth factor receptor, but not the estrogen receptor, in chemically induced lung carcinogenesis in female A/J mice (2014)
  • Author(s): Kishi S, Yokohira M, Yamakawa K, Saoo K, Imaida K
  • Journal Title: Oncol. Lett Volume: 8 Pages: 2379-2386
  • Peer Reviewed
• [Journal Article] Napsin A is possibly useful marker to predict the tumorigenic potential of lung bronchiolo-alveolar hyperplasia in F344 rats (2014)
  • Author(s): Yokohira M, Kishi S, Yamakawa K, Nakano Y, Ninomiya F, Kinouch s, Tanizawa J, Saoo K, Imaida K
  • Journal Title: Exp. Toxicol. Pathol Volume: 66 Pages: 117-123
  • DOI: 10.1016/j.etp.2013.11.002
  • Peer Reviewed
• [Journal Article] The peroxisome proliferator-activated receptor(PPAR)a agonist fenofibrate suppresses chemically induced lung alveolar proliferative lesions in male obese hyperlipidemic mice (2014)
  • Author(s): Kuno T, Hata K, Takamatsu M, Hara A, Hirose Y, Takahashi S, Imaida K, Tanaka T
  • Journal Title: Int. J. Mol. Sci Volume: 15 Pages: 9160-9172
  • DOI: 10.3390/ijms15059160
  • Peer Reviewed
• [Journal Article] Immunohistochemical characteristics of surfactant proteins-A, -B, -C and -D in inflammatory and tumorigenic lung lesions of F344 rats (2014)
  • Author(s): Yokohira M, Yamakawa K, Nakano Y, Numano T, Furukawa F, Kishi S, Ninomiya F, Kanie S, Hitotsumachi H, Saoo K, Imaida K
  • Journal Title: J. Toxicol. Pathol Volume: 27 Pages: 175-182
  • DOI: 10.1293/tox.2014-0020
  • Peer Reviewed
• [Journal Article] Rat strain differences in levels and effects of chronic inflammation due to intratracheal instillation of quartz on lung tumorigenesis induced by DHPN (2014)
  • Author(s): Nakano Y, Yokohira M, Hashimoto N, Yamakawa K, Kishi S, Ninomiya F, Kanie S, Saoo K, Imaida K
  • Journal Title: Exp. Toxicol. Pathol Volume: 66 Pages: 391-401
  • DOI: 10.1016/j.etp.2014.06.002
  • Peer Reviewed
• [Journal Article] Hepatoid giant cell tumor of tendon sheath-A rare morphologic variant case report (2014)
  • Author(s): Yoshimoto, T., Motoi, N., Kanda, H., Tanizawa, T., Shimoji, T., Matsumoto, S., Mukai, H., Ishikawa, Y., Machinami, R.
  • Journal Title: Pathology Res. Practice Volume: 14 Pages: 167-168
  • DOI: 10.1016/j.prp.2014.05.012
  • Peer Reviewed
• [Journal Article] FFT法と領域法を組み合わせたDNA ploidy解析によるがん診断法の研究 (2014)
  • Author(s): 日向奈恵、神田浩明、塩山高広、鈴木あかね、武田朴、石川雄一、山口俊晴、加藤洋
  • Journal Title: 生体医工学 Volume: 52 Pages: 136-144
  • DOI: 10.11239/jsmbe.52.136
  • Peer Reviewed
• [Journal Article] Premature termination of reprogramming in vivo leads to cancer development through altered epigenetic regulation (2014)
  • Author(s): Ohnishi K., Semi K., Yamamoto T., Shimizu M., Tanaka A., Mitsunaga K., Okita K., Osafune K., Arioka Y., Maeda T., Soejima H., Moriwaki H., Yamanaka S., Woltjen K., Yamada Y.
  • Journal Title: Cell Volume: 156 Pages: 663-77
  • DOI: 10.1016/j.cell.2014.01.005
  • Peer Reviewed
• [Journal Article] A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer (2014)
  • Author(s): Al Olama, A.A., Kote-Jarai Z., Bemdt S.I., Conti D.V., Schumacher F., Han Y., Benlloch S., Hazelett D.J., Wang Z., Saunders E., Leongamornlert D., Lindstrom S., Jugurnauth-Little S., Dadaev T., Tymrakiewicz M., Stram D.O., Rand K., Wan P., Stram A., Kubo M., et al.
  • Journal Title: Nat Genet Volume: 46 Pages: 1103-1109
  • DOI: 10.1038/ng.3094
  • Peer Reviewed
• [Journal Article] Infection with Porphyromonas gingivalis exacerbates endothelial injury in obese mice (2014)
  • Author(s): Ao, M., Miyauchi M., Inubushi T., Kitagawa M., Furusho H., Ando T., Ayuningtyas N.F., Nagasaki A., Ishihara K., Tahara H., Kozai K. and Takata T.
  • Journal Title: PLoS One Volume: 9 Pages: e110519
  • DOI: 10.1371/journal.pone.0110519
  • Peer Reviewed
• [Journal Article] Development of a SNP set for human identification : A set with high powers of discrimination which yields high genetic information from naturally degraded DNA samples in the Thai population (2014)
  • Author(s): Boonyarit, H., Mahasirimongkol S., Chavalvechakul N., Aoki M., Amitani H., Hosono N., Kamatani N., Kubo M. and Lertrit P.
  • Journal Title: Forensic Sci Int Genet Volume: 11 Pages: 166-173
  • DOI: 10.1016/j.fsigen.2014.03.010
  • Peer Reviewed
• [Journal Article] Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1,5q14.3 and 15q26.1 (2014)
  • Author(s): Cai, Q., Zhang B., Sung H., Low S.K., Kweon S.S., Shen C.Y., Matsuo K., Teo S.H., Kim M.K., Iwasaki M., Hartman M., Takahashi A., Ashikawa K., Matsuda K., Ito H., Kasuga Y., Iwata H., Tsugane S., Nakamura Y., Kubo M., et al.
  • Journal Title: Nat Genet Volume: 46 Pages: 886-890
  • DOI: 10.1038/ng.3041
  • Peer Reviewed
• [Journal Article] Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians (2014)
  • Author(s): Chen, P., Takeuchi F., Lee J.Y., Li H., Wu J.Y., Tabara Y., Goodarzi M.O., Pereira M.A., Kim Y.J., Go M.J., Stram D.O., Vithana E., Isono M., Yamamoto K., Ohnaka K., Takayanagi R., Kita Y., Ueshima H., Okada Y., Kubo M., et al.
  • Journal Title: Diabetes Volume: 63 Pages: 2551-2562
  • DOI: 10.2337/db13-1815
  • Peer Reviewed
• [Journal Article] Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101(Alliance) (2014)
  • Author(s): Chhibber, A., Mefford J., Stahl E.A., Pendergrass S.A., Baldwin R.M., Owzar K., Li M., Winer E.P., Hudis C.A., Zembutsu H., Kubo M., Nakamura Y., McLeod H.L., Ratain M.J., Shulman L.N., Ritchie M.D., Plenge R.M., Witte J.S. and Kroetz D.L.
  • Journal Title: Pharmacogenomics J Volume: 14 Pages: 336-342
  • DOI: 10.1038/tpj.2014.2
  • Peer Reviewed
• [Journal Article] Establishment of CYP2D6 reference samples by multiple validated genotyping platforms (2014)
  • Author(s): Fang, H., Liu X., Ramirez J., Choudhury N., Kubo M., Im H.K., Konkashbaev A., Cox N.J., Ratain M.J., Nakamura Y. and O'Donnell P.H.
  • Journal Title: Pharmacogenomics J Volume: 14 Pages: 564-572
  • DOI: 10.1038/tpj.2014.27
  • Peer Reviewed
• [Journal Article] Genetic variants in transcription factors are associated with the pharmacokinetics and pharmacodynamics of metformin (2014)
  • Author(s): Goswami, S., Yee S.W., Stocker S., Mosley J.D., Kubo M., Castro R., Mefford J.A., Wen C., Liang X., Witte J., Brett C., Maeda S., Simpson M.D., Hedderson M.M., Davis R.L., Roden D.M., Giacomini K.M. and Savic R.M.
  • Journal Title: Clin Pharmacol Ther Volume: 96 Pages: 370-379
  • DOI: 10.1038/clpt.2014.109
  • Peer Reviewed
• [Journal Article] A novel RET rearrangement (ACBD5/RET) by pericentric inversion, inv(10)(p12.1 ; q11.2), in papillary thyroid cancer from an atomic bomb survivor exposed to high-dose radiation (2014)
  • Author(s): Hamatani, K., Eguchi H., Koyama K., Mukai M., Nakachi K. and Kusunoki Y.
  • Journal Title: Oncol Rep Volume: 32 Pages: 1809-1814
  • DOI: 10.3892/or.2014.3449
  • Peer Reviewed
• [Journal Article] Associations between hOGG1 Ser326Cys polymorphism and increased body mass index and fasting glucose level in the Japanese general population (2014)
  • Author(s): Hara, M., Nakamura K., Nanri H., Nishida Y., Hishida A., Kawai S., Hamajima N., Kita Y., Suzuki S., Mantjoro E.M., Ohnaka K., Uemura H., Matsui D., Oze I., Mikami H., Kubo M., Tanaka H. and Japan Multi-Institutional Collaborative Cohort Study Group
  • Journal Title: J Epidemiol Volume: 24 Pages: 379-384
  • Peer Reviewed
• [Journal Article] Cancer Philosophy～Thinking“Cancer Cells”Deeply (2014)
  • Author(s): Hino, O
  • Journal Title: Juntendo Medical Journal Volume: 60 Pages: 200-209
  • Peer Reviewed
• [Journal Article] Telomeric g-tail length and hospitalization for cardiovascular events in hemodialysis patients (2014)
  • Author(s): Hirashio, S., Nakashima A., Doi S., Anno K., Aoki E., Shimamoto A., Yorioka N., Kohno N., Masaki T. and Tahara H
  • Journal Title: Clin J Am Soc Nephrol Volume: 9 Pages: 2117-2122
  • DOI: 10.2215/CJN.10010913
  • Peer Reviewed
• [Journal Article] Retrospective analysis of large-scale research screening of construction workers for the early diagnosis of mesothelioma (2014)
  • Author(s): Hirohashi, T., Igarashi K., Abe M., Maeda M. and Hino O.
  • Journal Title: Mol Clin Oncol Volume: 2 Pages: 26-30
  • DOI: 10.3892/mco.2013.197
  • Peer Reviewed
• [Journal Article] CBP-93872 inhibits NBS1-mediated ATR activation, abrogating maintenance of the DNA double-strand break-specific G2 checkpoint (2014)
  • Author(s): Hirokawa, T., Shiotani B., Shimada M., Murata K., Johmura Y., Haruta M., Tahara H., Takeyama H. and Nakanishi M.
  • Journal Title: Cancer Res Volume: 74 Pages: 3880-3889
  • DOI: 10.1158/0008-5472.CAN-13-3604
  • Peer Reviewed
• [Journal Article] GCK, GCKR polymorphisms and risk of chronic kidney disease in Japanese individuals : data from the J-MICC Study (2014)
  • Author(s): Hishida, A., Takashima N., Turin T.C., Kawai S., Wakai K., Hamajima N., Hosono S., Nishida Y., Suzuki S., Nakahata N., Mikami H., Ohnaka K., Matsui D., Katsuura-Kamano S., Kubo M., Tanaka H. and Kita Y.
  • Journal Title: J Nephrol Volume: 27 Pages: 143-149
  • DOI: 10.1007/s40620-013-0025-0
  • Peer Reviewed
• [Journal Article] Polymorphisms of genes involved in lipid metabolism and risk of chronic kidney disease in Japanese-cross-sectional data from the J-MICC study (2014)
  • Author(s): Hishida, A., Wakai K., Naito M., Suma S., Sasakabe T., Hamajima N., Hosono S., Horita M., Turin T.C., Suzuki S., Kairupan T.S., Mikami H., Ohnaka K., Watanabe I., Uemura H., Kubo M., Tanaka H, and J-Micc Study Group
  • Journal Title: Lipids Health Dis Volume: 13 Pages: 162
  • DOI: 10.1186/1476-511X-13-162
  • Peer Reviewed
• [Journal Article] TERT attenuated ER stress-induced cell death (2014)
  • Author(s): Hosoi, T., Inoue Y., Nakatsu K., Matsushima N., Kiyose N., Shimamoto A., Tahara H. and Ozawa K.
  • Journal Title: Biochem Biophys Res Commun Volume: 447 Pages: 378-382
  • DOI: 10.1016/j.bbrc.2014.04.034
  • Peer Reviewed
• [Journal Article] Circulating tumor cell count during zoledronic acid treatment in men with metastatic prostate cancer : a pilot study (2014)
  • Author(s): Ide, H., Lu Y., Tanaka T., Wakumoto Y., Kitamura K., Muto S., Yamaguchi R., Masumori N. and Horie S.
  • Journal Title: Prostate Int Volume: 2 Pages: 147-151
  • DOI: 10.12954/PI.14056
  • Peer Reviewed
• [Journal Article] Asbestos-related mesothelioma : Prevention, early detection, treatment (2014)
  • Author(s): Imai, M. and Hino O.
  • Journal Title: JSM Clinical Oncology and Research Volume: 2 Issue: 3 Pages: 1018
  • Peer Reviewed
• [Journal Article] ERC/mesothelin is expressed in human gastric cancer tissues and cell lines (2014)
  • Author(s): Ito, T., Kajino K., Abe M., Sato K., Maekawa H., Sakurada M., Orita H., Wada R., Kajiyama Y. and Hino O.
  • Journal Title: Oncol Rep Volume: 31 Pages: 27-33
  • DOI: 10.3892/or.2013.2803
  • Peer Reviewed
• [Journal Article] Association of EPAS1 gene rs4953354 polymorphism with susceptibility to lung adenocarcinoma in female Japanese non-smokers (2014)
  • Author(s): Iwamoto, S., Tanimoto K., Nishio Y., Putra A.C., Fuchita H., Ohe M., Sutani A., Kuraki T., Hiyama K., Murakami I., Eguchi H. and Isobe T.
  • Journal Title: J Thorac Oncol Volume: 9 Pages: 1709-1713
  • DOI: 10.1097/JTO.0000000000000309
  • Peer Reviewed
• [Journal Article] Citalopram and escitalopram plasma drug and metabolite concentrations : genome-wide associations (2014)
  • Author(s): Ji, Y., Schaid D.J., Desta Z., Kubo M., Batzler A.J., Snyder K., Mushiroda T., Kamatani N., Ogburn E., Hall-Flavin D., Flockhart D., Nakamura Y., Mrazek D.A. and Weinshilboum R.M.
  • Journal Title: Br J Clin Pharmacol Volume: 78 Pages: 373-383
  • DOI: 10.1111/bcp.12348
  • Peer Reviewed
• [Journal Article] EP2 signaling mediates suppressive effects of celecoxib on androgen receptor expression and cell proliferation in prostate cancer (2014)
  • Author(s): Kashiwagi, E., Shiota M., Yokomizo A., Inokuchi J., Uchiumi T. and Naito S.
  • Journal Title: Prostate Cancer Prostatic Dis Volume: 17 Pages: 10-17
  • DOI: 10.1038/pcan.2013.53
  • Peer Reviewed
• [Journal Article] A polymorphism near MC4R gene (rs17782313) is associated with serum triglyceride levels in the general Japanese population : the J-MICC Study (2014)
  • Author(s): Katsuura-Kamano, S., Uemura H., Arisawa K., Yamaguchi M., Hamajima N., Wakai K., Okada R., Suzuki S., Taguchi N., Kita Y., Ohnaka K., Kairupan T.S., Matsui D., Oze I., Mikami H., Kubo M. and Tanaka H.
  • Journal Title: Endocrine Volume: 47 Pages: 81-89
  • DOI: 10.1007/s12020-014-0306-y
  • Peer Reviewed
• [Journal Article] Trans-ethnic meta-analysis of white blood cell phenotypes (2014)
  • Author(s): Keller, M.F., Reiner A.P., Okada Y., van Rooij F.J., Johnson A.D., Chen M.H., Smith A.V., Morris A.P., Tanaka T., Ferrucci L., Zonderman A.B., Lettre G., Kamatani Y., Matsuda K., Kamatani N., Nakamura Y., Kubo M., Takahashi A., Wilson J.G., BioBank Japan Project Working Groups, et al.
  • Journal Title: Hum Mol Genet Volume: 23 Pages: 6944-6960
  • DOI: 10.1093/hmg/ddu401
  • Peer Reviewed
• [Journal Article] SOD3 acts as a tumor suppressor in PC-3 prostate cancer cells via hydrogen peroxide accumulation (2014)
  • Author(s): Kim, J., Mizokami A., Shin M., Izumi K., Konaka H., Kadono Y., Kitagawa Y., Keller E.T., Zhang J. and Namiki M.
  • Journal Title: Anticancer Res Volume: 34 Pages: 2821-2831
  • Peer Reviewed
• [Journal Article] A genome-wide association study to identify genomic modulators of rate control therapy in patients with atrial fibrillation (2014)
  • Author(s): Kolek, M.J., Edwards T.L., Muhammad R., Balouch A., Shoemaker M.B., Blair M.A., Kor K.C., Takahashi A., Kubo M., Roden D.M., Tanaka T. and Darbar D.
  • Journal Title: Am J Cardiol Volume: 114 Pages: 593-600
  • DOI: 10.1016/j.amjcard.2014.05.040
  • Peer Reviewed
• [Journal Article] Combination of bevacizumab and acyclic retinoid inhibits the growth of hepatocellular carcinoma xenografts (2014)
  • Author(s): Kubota, M., Shimizu M., Baba A., Ohno T., Kochi T., Shirakami Y. and Moriwaki H.
  • Journal Title: J Nutr Sci Vitaminol (Tokyo) Volume: 60 Pages: 357-362
  • DOI: 10.3177/jnsv.60.357
  • Peer Reviewed
• [Journal Article] Aromatase inhibitor-associated bone fractures : a case-cohort GWAS and functional genomics (2014)
  • Author(s): Liu, M., Goss P.E., Ingle J.N., Kubo M., Furukawa Y., Batzler A., Jenkins G.D., Carlson E.E., Nakamura Y., Schaid D.J., Chapman J.A., Shepherd L.E., Ellis M.J., Khosla S., Wang L. and Weinshilboum R.M.
  • Journal Title: Mol Endocrinol Volume: 28 Pages: 1740-1751
  • DOI: 10.1210/me.2014-1147
  • Peer Reviewed
• [Journal Article] Minimal experimental requirements for definition of extracellular vesicles and their functions : a position statement from the International Society for Extracellular Vesicles (2014)
  • Author(s): Lotvall, J., Hill A.F., Hochberg F., Buzas E.I., Di Vizio D., Gardiner C., Gho Y.S., Kurochkin I.V., Mathivanan S., Quesenberry P., Sahoo S., Tahara H., Wauben M.H., Witwer K.W. and Thery C.
  • Journal Title: J Extracell Vesicles Volume: 3 Pages: 26913
  • DOI: 10.3402/jev.v3.26913
  • Peer Reviewed
• [Journal Article] Genome-wide association study : a useful tool to identify common genetic variants associated with drugtoxicity and efficacy in cancer pharmacogenomics (2014)
  • Author(s): Low, S.K., Takahashi A., Mushiroda T. and Kubo M.
  • Journal Title: Clin Cancer Res Volume: 20 Pages: 2541-2552
  • DOI: 10.1158/1078-0432.CCR-13-2755
  • Peer Reviewed
• [Journal Article] Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese (2014)
  • Author(s): Lubitz, S.A., Lunetta K.L., Lin H., Arking D.E., Trompet S., Li G., Krijthe B.P., Chasman D.I., Barnard J., Kleber M.E., Dorr M., Ozaki K., Smith A.V., Muller-Nurasyid M., Walter S., Agarwal S.K., Kubo M., Tanaka T., Heckbert S.R., Jukema J.W., et al.
  • Journal Title: J Am Coll Cardiol Volume: 63 Pages: 1200-1210
  • DOI: 10.1016/j.jacc.2013.12.015
  • Peer Reviewed
• [Journal Article] Ethical challenges for the design and conduct of mega-biobanking from Great East Japan Earthquake victims (2014)
  • Author(s): Matsui, K. and Tashiro S.
  • Journal Title: BMC Med Ethics Volume: 15 Pages: 55
  • DOI: 10.1186/1472-6939-15-55
  • Peer Reviewed
• [Journal Article] DSE-FRET : A new anticancer drug screening assay for DNA binding proteins (2014)
  • Author(s): Miyagi, T., Shiotani B., Miyoshi R., Yamamoto T., Oka T., Umezawa K., Ochiya T., Takano M. and Tahara H.
  • Journal Title: Cancer Sci Volume: 105 Pages: 870-874
  • DOI: 10.1111/cas.12420
  • Peer Reviewed
• [Journal Article] Proposed salvage treatment strategy for biochemical failure after radical prostatectomy in patients with prostate cancer : a retrospective study (2014)
  • Author(s): Miyake, M., Tanaka N., Asakawa I., Morizawa Y., Anai S., Torimoto K., Aoki K., Yoneda T., Hasegawa M., Konishi N. and Fujimoto K.
  • Journal Title: Radiat Oncol Volume: 9 Pages: 208
  • DOI: 10.1186/1748-717X-9-208
  • Peer Reviewed
• [Journal Article] Photodynamic diagnosis of shed prostate cancer cells in voided urine treated with 5-aminolevulinic acid (2014)
  • Author(s): Nakai, Y., Anai S., Kuwada M., Miyake M., Chihara Y., Tanaka N., Hirayama A., Yoshida K., Hirao Y. and Fujimoto K.
  • Journal Title: BMC Urol Volume: 14 Pages: 59
  • DOI: 10.1186/1471-2490-14-59
  • Peer Reviewed
• [Journal Article] A genome-wide association study identifies susceptibility loci for ossification of the posterior longitudinal ligament of the spine (2014)
  • Author(s): Nakajima, M., Takahashi A., Tsuji T., Karasugi T., Baba H., Uchida K., Kawabata S., Okawa A., Shindo S., Takeuchi K., Taniguchi Y., Maeda S., Kashii M., Seichi A., Nakajima H., Kawaguchi Y., Fujibayashi S., Takahata M., Tanaka T., Kubo M., et al.
  • Journal Title: Nat Genet Volume: 46 Pages: 1012-1016
  • DOI: 10.1038/ng.3045
  • Peer Reviewed
• [Journal Article] Common dysfunctional variants of ABCG2 have stronger impact on hyperuricemia progression than typical environmental risk factors (2014)
  • Author(s): Nakayama, A., Matsuo H., Nakaoka H., Nakamura T., Nakashima H., Takada Y., Oikawa Y., Takada T., Sakiyama M., Shimizu S., Kawamura Y., Chiba T., Abe J., Wakai K., Kawai S., Okada R., Tamura T., Shichijo Y., Akashi A., Suzuki H., et al.
  • Journal Title: Sci Rep Volume: 4 Pages: 5227
  • DOI: 10.1038/srep05227
  • Peer Reviewed
• [Journal Article] Objectively measured physical activity and inflammatory cytokine levels in middle-aged Japanese people (2014)
  • Author(s): Nishida, Y., Higaki Y., Taguchi N., Hara M., Nakamura K., Nanri H., Imaizumi T., Sakamoto T., Horita M., Shinchi K. and Tanaka K.
  • Journal Title: Prev Med Volume: 64 Pages: 81-87
  • DOI: 10.1016/j.ypmed.2014.04.004
  • Peer Reviewed
• [Journal Article] Association between KCNJ6 (GIRK2) gene polymorphism rs2835859 and post-operative analgesia, pain sensitivity, and nicotine dependence (2014)
  • Author(s): Nishizawa, D., Fukuda K., Kasai S., Ogai Y., Hasegawa J., Sato N., Yamada H., Tanioka F., Sugimura H., Hayashida M. and Ikeda K.
  • Journal Title: J Pharmacol Sci Volume: 126 Pages: 253-263
  • Peer Reviewed
• [Journal Article] Pyrrole-imidazole polyamide targeted to break fusion sites in TMPRSS2 and ERG gene fusion represses prostate tumor growth (2014)
  • Author(s): Obinata, D., Ito A., Fujiwara K., Takayama K., Ashikari D., Murata Y., Yamaguchi K., Urano T., Fujimura T., Fukuda N., Soma M., Watanabe T., Nagase H., Inoue S. and Takahashi S.
  • Journal Title: Cancer Sci Volume: 105 Pages: 1272-1278
  • DOI: 10.1111/cas.12493
  • Peer Reviewed
• [Journal Article] IFNL4/IL-28B haplotype structure and its impact on susceptibility to hepatitis C virus and treatment response in the Japanese population (2014)
  • Author(s): Ochi, H., Miki D., Hayes C.N., Abe H., Hayashida Y., Kubo M. and Chayama K.
  • Journal Title: J Gen Virol Volume: 95 Pages: 1297-1306
  • DOI: 10.1099/vir.0.060103-0
  • Peer Reviewed
• [Journal Article] Genetics of rheumatoid arthritis contributes to biology and drug discovery (2014)
  • Author(s): Okada, Y., Wu D., Trynka G., Raj T., Terao C., Ikari K., Kochi Y., Ohmura K., Suzuki A., Yoshida S., Graham R.R., Bhangale T., Denny J.C., Carroll R.J., Eyler A.E., Kawaguchi T., Kamatani Y., Taniguchi A., Yamada R., Kubo M., et al.
  • Journal Title: Nature Volume: 506 Pages: 376-381
  • DOI: 10.1038/nature12873
  • Peer Reviewed
• [Journal Article] Survey of survival among patients with hepatitis C virus-related hepatocellular carcinoma treated with peretinoin, an acyclic retinoid, after the completion of a randomized, placebo-controlled trial (2014)
  • Author(s): Okita, K., Izumi N., Ikeda K., Osaki Y., Numata K., Ikeda M., Kokudo N., Imanaka K., Nishiguchi S., Kondo S., Nishigaki Y., Shiomi S., Ueshima K., Isoda N., Karino Y., Kudo M., Tanaka K., Kaneko S., Moriwaki H., Makuuchi M., et al.
  • Journal Title: J Gastroenterol
  • DOI: 10.1007/s00535-014-0996-1
  • Description: Epub ahead of print
  • Peer Reviewed
• [Journal Article] Coffee and green tea consumption is associated with upper aerodigestive tractcancer in Japan (2014)
  • Author(s): Oze, I., Matsuo K., Kawakita D., Hosono S., Ito H., Watanabe M., Hatooka S., Hasegawa Y., Shinoda M., Tajima K. and Tanaka H.
  • Journal Title: Int J Cancer Volume: 135 Issue: 2 Pages: 391-400
  • DOI: 10.1002/ijc.28653
  • Peer Reviewed
• [Journal Article] Higher levels of antibodies to the tumour-associated antigen cyclin B1 in cancer-free individuals than in patients with breast cancer (2014)
  • Author(s): Pandey, J.P., Kistner-Griffin E., Namboodiri A.M., Iwasaki M., Kasuga Y., Hamada G.S. and Tsugane S.
  • Journal Title: Clin Exp Immunol Volume: 178 Pages: 75-78
  • DOI: 10.1111/cei.12385
  • Peer Reviewed
• [Journal Article] Genetic predictors associated with improvement of asthma symptoms in response to inhaled corticosteroids (2014)
  • Author(s): Park, H.W., Dahlin A., Tse S., Duan Q.L., Schuemann B., Martinez F.D., Peters S.P., Szefler S.J., Lima J.J., Kubo M., Tamari M. and Tantisira K.G.
  • Journal Title: J Allergy Clin Immunol Volume: 133 Pages: 664-669
  • DOI: 10.1016/j.jaci.2013.12.1042
  • Peer Reviewed
• [Journal Article] Acute case-fatality rates of stroke and acute myocardial infarction in a Japanese population : Takashima stroke and AMI registry, 1989-2005 (2014)
  • Author(s): Rumana, N., Kita Y., Turin T.C., Nakamura Y., Takashima N., Ichikawa M., Sugihara H., Morita Y., Hirose K., Kawakami K., Okayama A., Miura K. and Ueshima H.
  • Journal Title: Int J Stroke Volume: 9 Suppl A100 Pages: 69-75
  • DOI: 10.1111/ijs.12288
  • Peer Reviewed
• [Journal Article] A common variant of organic anion transporter 4(OAT4/SLC22A11) gene is associated with renal underexcretion type gout (2014)
  • Author(s): Sakiyama, M., Matsuo H., Shimizu S., Nakashima H., Nakayama A., Chiba T., Naito M., Takada T., Suzuki H., Hamajima N., Ichida K., Shimizu T. and Shinomiya N.
  • Journal Title: Drug Metab Pharmacokinet Volume: 29 Pages: 208-210
  • Peer Reviewed
• [Journal Article] Ethnic Differences in ATP-binding Cassette Transporter, Sub-family G, Member2 (ABCG2/BCRP) : Genotype Combinations and Estimated Functions (2014)
  • Author(s): Sakiyama, M., Matsuo H., Takada Y., Nakamura T., Nakayama A., Takada T., Kitajiri S., Wakai K., Suzuki H. and Shinomiya N.
  • Journal Title: Drug Metab Pharmacokinet Volume: 29 Pages: 490-492
  • DOI: 10.2133/dmpk.DMPK-14-SC-041
  • Peer Reviewed
• [Journal Article] Newly established ELISA for N-ERC/mesothelin improves diagnostic accuracy in patients with suspected pleural mesothelioma (2014)
  • Author(s): Sato, T., Suzuki Y., Mori T., Maeda M., Abe M., Hino O. and Takahashi K.
  • Journal Title: Cancer Med Volume: 3 Pages: 1377-1384
  • DOI: 10.1002/cam4.297
  • Peer Reviewed
• [Journal Article] The construction of risk prediction models using GWAS data and its application to a type 2 diabetes prospective cohort (2014)
  • Author(s): Shigemizu, D., Abe T., Morizono T., Johnson T.A., Boroevich K.A., Hirakawa Y., Ninomiya T., Kiyohara Y., Kubo M., Nakamura Y., Maeda S. and Tsunoda T.
  • Journal Title: PLoS One Volume: 9 Pages: e92549
  • DOI: 10.1371/journal.pone.0092549
  • Peer Reviewed
• [Journal Article] Reprogramming suppresses premature senescence phenotypes of Werner syndromecells and maintains chromosomal stability over long-term culture (2014)
  • Author(s): Shimamoto, A., Kagawa H., Zensho K., Sera Y., Kazuki Y., Osaki M., Oshimura M., Ishigaki Y., Hamasaki K., Kodama Y., Yuasa S., Fukuda K., Hirashima K., Seimiya H., Koyama H., Shimizu T., Takemoto M., Yokote K., Goto M. and Tahara H.
  • Journal Title: PLoS One Volume: 9 Pages: e112900
  • DOI: 10.1371/journal.pone.0112900
  • Peer Reviewed
• [Journal Article] Gender-specific associations of perceived stress and coping strategies with C-reactive protein in middle-aged and older men and women (2014)
  • Author(s): Shimanoe, C., Otsuka Y., Hara M., Nanri H., Nishida Y., Nakamura K., Higaki Y., Imaizumi T., Taguchi N., Sakamoto T., Horita M., Shinchi K. and Tanaka K.
  • Journal Title: Int J Behav Med Volume: 21 Pages: 821-832
  • DOI: 10.1007/s12529-013-9341-y
  • Peer Reviewed
• [Journal Article] Pharmaceutical and nutraceutical approaches for preventing liver carcinogenesis : chemoprevention of hepatocellular carcinoma using acyclic retinoid and branched-chain amino acids (2014)
  • Author(s): Shimizu, M., Shirakami Y., Hanai T., Imai K., Suetsugu A., Takai K., Shiraki M. and Moriwaki H.
  • Journal Title: Mol Nutr Food Res Volume: 58 Pages: 124-135
  • DOI: 10.1002/mnfr.201300538
  • Peer Reviewed
• [Journal Article] Impaired 8-hydroxyguanine repair activity of MUTYH variant p. Arg109Trp found in a Japanese patient with early-onset colorectal cancer (2014)
  • Author(s): Shinmura, K., Goto M., Tao H., Kato H., Suzuki R., Nakamura S., Matsuda T., Yin G., Morita M., Kono S. and Sugimura H.
  • Journal Title: Oxid Med Cell Longev Volume: 2014 Pages: 617351
  • DOI: 10.1155/2014/617351
  • Peer Reviewed
• [Journal Article] RSPO fusion transcripts in colorectal cancer in Japanese population (2014)
  • Author(s): Shinmura, K., Kahyo T., Kato H., Igarashi H., Matsuura S., Nakamura S., Kurachi K., Nakamura T., Ogawa H., Funai K., Tanahashi M., Niwa H. and Sugimura H.
  • Journal Title: Mol Biol Rep Volume: 41 Pages: 5375-5384
  • DOI: 10.1007/s11033-014-3409-x
  • Peer Reviewed
• [Journal Article] PLK4 overexpression and its effect on centrosome regulation and chromosome stability in human gastric cancer (2014)
  • Author(s): Shinmura, K., Kurabe N., Goto M., Yamada H., Natsume H., Konno H. and Sugimura H.
  • Journal Title: Mol Biol Rep Volume: 41 Pages: 6635-6644
  • DOI: 10.1007/s11033-014-3546-2
  • Peer Reviewed
• [Journal Article] Transgenic expression of the N525S-tuberin variant in Tsc2 mutant (Eker) rats causes dominant embryonic lethality (2014)
  • Author(s): Shiono, M., Kobayashi T., Takahashi R., Ueda M., Ishioka C. and Hino O
  • Journal Title: Sci Rep Volume: 4 Pages: 5927
  • DOI: 10.1038/srep05927
  • Peer Reviewed
• [Journal Article] The oncological outcomes and risk stratification in docetaxel chemotherapy for castration-resistant prostate cancer (2014)
  • Author(s): Shiota, M., Yokomizo A., Adachi T., Koga H., Yamaguchi A., Imada K., Takeuchi A., Kiyoshima K., Inokuchi J., Tatsugami K. and Naito S.
  • Journal Title: Jpn J Clin Oncol Volume: 44 Pages: 860-867
  • DOI: 10.1093/jjco/hyu081
  • Peer Reviewed
• [Journal Article] The feature of metabolic syndrome is a risk factor for biochemical recurrence after radical prostatectomy (2014)
  • Author(s): Shiota, M., Yokomizo A., Takeuchi A., Imada K., Kiyoshima K., Inokuchi J., Tatsugami K. and Naito S.
  • Journal Title: J Surg Oncol Volume: 110 Pages: 476-481
  • DOI: 10.1002/jso.23677
  • Peer Reviewed
• [Journal Article] Risk factors for febrile neutropenia in patients receiving docetaxel chemotherapy for castration-resistant prostate cancer (2014)
  • Author(s): Shiota, M., Yokomizo A., Takeuchi A., Imada K., Kiyoshima K., Inokuchi J., Tatsugami K. and Naito S.
  • Journal Title: Support Care Cancer Volume: 22 Pages: 3219-3226
  • DOI: 10.1007/s00520-014-2328-7
  • Peer Reviewed
• [Journal Article] Integrated analysis of whole genome and transcriptome sequencing reveals diverse transcriptomic aberrations driven by somatic genomic changes in liver cancers (2014)
  • Author(s): Shiraishi, Y., Fujimoto A., Furuta M., Tanaka H., Chiba K., Boroevich K.A., Abe T., Kawakami Y., Ueno M., Gotoh K., Ariizumi S., Shibuya T., Nakano K., Sasaki A., Maejima K., Kitada R., Hayami S., Shigekawa Y., Marubashi S., Yamada T., et al.
  • Journal Title: PLoS One Volume: 9 Pages: e114263
  • DOI: 10.1371/journal.pone.0114263
  • Peer Reviewed
• [Journal Article] Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation (2014)
  • Author(s): Sinner, M.F., Tucker N.R., Lunetta K.L., Ozaki K., Smith J.G., Trompet S., Bis J.C., Lin H., Chung M.K., Nielsen J.B., Lubitz S.A., Krijthe B.P., Magnani J.W., Ye J., Tsunoda T., Kubo M., Ebana Y., Furukawa T., Isobe M., Tanaka T., et al.
  • Journal Title: Circulation Volume: 130 Pages: 1225-1235
  • DOI: 10.1161/CIRCULATIONAHA.114.009892
  • Peer Reviewed
• [Journal Article] Subtypes of metabolic syndrome and of other risk factors in Japanese women with erosive esophagitis (2014)
  • Author(s): Sogabe, M., Okahisa T., Yamanoi A. and Takayama T.
  • Journal Title: Medicine (Baltimore) Volume: 93 Pages: e276
  • DOI: 10.1097/MD.0000000000000276
  • Peer Reviewed
• [Journal Article] TCGA output and practice of gastric cancer (2014)
  • Author(s): Sugimura, H
  • Journal Title: Translational Gastrointestinal Cancer
  • Description: Publish Ahead of Print
  • Peer Reviewed
• [Journal Article] Counts of Slackia sp. strain NATTS in intestinal flora are correlated to serum concentrations of equol both in prostate cancer cases and controls in Japanese men (2014)
  • Author(s): Sugiyama, Y., Nagata Y., Fukuta F., Takayanagi A., Masumori N., Tsukamoto T., Akasaka H., Ohnishi H., Saito S., Miura T., Moriyama K., Tsuji H., Akaza H. and Mori M.
  • Journal Title: Asian Pac J Cancer Prev Volume: 15 Pages: 2693-2697
  • Peer Reviewed
• [Journal Article] A rare Japanese case with a NUT midline carcinoma in the nasal cavity : a case report with immunohistochemical and genetic analyses (2014)
  • Author(s): Suzuki, S., Kurabe N., Minato H., Ohkubo A., Ohnishi I., Tanioka F. and Sugimura H.
  • Journal Title: Pathol Res Pract Volume: 210 Pages: 383-388
  • DOI: 10.1016/j.prp.2014.01.013
  • Peer Reviewed
• [Journal Article] NSD3-NUT-expressing midline carcinoma of the lung : First characterization of primary cancer tissue (2014)
  • Author(s): Suzuki, S., Kurabe N., Ohnishi I., Yasuda K., Aoshima Y., Naito M., Tanioka F. and Sugimura H.
  • Journal Title: Pathol Res Pract
  • DOI: 10.1016/j.prp.2014.10.013
  • Description: Epub ahead of print
  • Peer Reviewed
• [Journal Article] Extensive goblet cell metaplasia of the peripheral lung may harbor precancerous molecular changes : comparison of two cases (2014)
  • Author(s): Tajima, S., Kurabe N., Okudela K., Yajima K., Takahashi T., Neyatani H., Sugimura H. and Koda K.
  • Journal Title: Pathol Int Volume: 64 Pages: 533-538
  • DOI: 10.1111/pin.12204
  • Peer Reviewed
• [Journal Article] Radiation-induced breast angiosarcoma with a confirmative feature of c-MYC amplification (2014)
  • Author(s): Tajima, S., Mochizuki R., Sugimura H. and Hoshi S.
  • Journal Title: Jpn J Clin Oncol Volume: 44 Pages: 702-703
  • DOI: 10.1093/jjco/hyu064
  • Peer Reviewed
• [Journal Article] Advances in cancer epidemiology in Japan (2014)
  • Author(s): Tanaka, H.
  • Journal Title: Int J Cancer Volume: 134 Pages: 747-754
  • DOI: 10.1002/ijc.28519
  • Peer Reviewed
• [Journal Article] The biochemical recurrence-free rate in patients who underwent prostate low-dose-rate brachytherapy, using two different definitions (2014)
  • Author(s): Tanaka, N., Asakawa I., Katayama E., Hirayama A., Hasegawa M., Konishi N. and Fujimoto K.
  • Journal Title: Radiat Oncol Volume: 9 Pages: 107
  • DOI: 10.1186/1748-717X-9-107
  • Peer Reviewed
• [Journal Article] Use of alpha-1 adrenoceptor antagonists in patients who underwent low-dose-rate brachytherapy for prostate cancer-a randomized controlled trial of silodosin versus naftopidil (2014)
  • Author(s): Tanaka, N., Torimoto K., Asakawa I., Miyake M., Anai S., Hirayama A., Hasegawa M., Konishi N. and Fujimoto K.
  • Journal Title: Radiat Oncol Volume: 9 Pages: 1163
  • DOI: 10.1186/s13014-014-0302-7
  • Peer Reviewed
• [Journal Article] Nadir PSA level and time to nadir PSA are prognostic factors in patients with metastatic prostate cancer (2014)
  • Author(s): Tomioka, A., Tanaka N., Yoshikawa M., Miyake M., Anai S., Chihara Y., Okajima E., Hirayama A., Hirao Y. and Fujimoto K.
  • Journal Title: BMC Urol Volume: 14 Pages: 33
  • DOI: 10.1186/1471-2490-14-33
  • Peer Reviewed
• [Journal Article] Utility of PAX8 mouse monoclonal antibody in the diagnosis of thyroid, thymic, pleural and lung tumours : a comparison with polyclonal PAX8 antibody (2014)
  • Author(s): Toriyama, A., Mori T., Sekine S., Yoshida A., Hino O. and Tsuta K.
  • Journal Title: Histopathology Volume: 65 Pages: 465-472
  • DOI: 10.1111/his.12405
  • Peer Reviewed
• [Journal Article] Body mass index and breast cancer risk in Japan : a pooled analysis of eight population-based cohort studies (2014)
  • Author(s): Wada, K., Nagata C., Tamakoshi A., Matsuo K., Oze I., Wakai K., Tsuji I., Sugawara Y., Mizoue T., Tanaka K., Iwasaki M., Inoue M., Tsugane S., Sasazuki S., Research Group for the D. and Evaluation of Cancer Prevention Strategies in Japan
  • Journal Title: Ann Oncol Volume: 25 Pages: 519-524
  • DOI: 10.1093/annonc/mdt542
  • Peer Reviewed
• [Journal Article] Sugars, sucrose and colorectal cancer risk : the Fukuoka colorectal cancer study (2014)
  • Author(s): Wang, Z., Uchida K., Ohnaka K., Morita M., Toyomura K., Kono S., Ueki T., Tanaka M., Kakeji Y., Maehara Y., Okamura T., Ikejiri K., Futami K., Maekawa T., YasunamiY., Takenaka K., Ichimiya H. and Terasaka R.
  • Journal Title: Scand J Gastroenterol Volume: 49 Pages: 581-588
  • DOI: 10.3109/00365521.2013.822091
  • Peer Reviewed
• [Journal Article] Imputation and subset-based association analysis across different cancertypes identifies multiple independent risk loci in the TERT-CLPTMIL region onchromosome 5p15.33 (2014)
  • Author(s): Wang, Z., Zhu B., Zhang M., Parikh H., Jia J., Chung C.C., Sampson J.N., Hoskins J.W., Hutchinson A., Burdette L., Ibrahim A., Ito H., Kitahara C.M., Kohno T., Kunitoh H., Matsuo K., Niwa S., Shiraishi K., Tanaka H., Yatabe Y., et al.
  • Journal Title: Hum Mol Genet Volume: 23 Pages: 6616-6633
  • DOI: 10.1093/hmg/ddu363
  • Peer Reviewed
• [Journal Article] Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index (2014)
  • Author(s): Wen, W., Zheng W., Okada Y., Takeuchi F., Tabara Y., Hwang J.Y., Dorajoo R., Li H., Tsai F.J., Kubo M., Yamamoto K., Ohkubo T., Tsunoda T., Akiyama K., Takashima N., Isomura M., Umemura S., Isono M., Takayanagi R., Kang D.H., et al.
  • Journal Title: Hum Mol Genet Volume: 23 Pages: 5492-5504
  • DOI: 10.1093/hmg/ddu248
  • Peer Reviewed
• [Journal Article] Sexy Small Copy Numbers in Hereditary Gastric Carcinogenesis (2014)
  • Author(s): Yamada, H., Sakamoto H. and Sugimura H.
  • Journal Title: J of Gastrointestinal & Digestive System Volume: 4 Pages: 205
  • DOI: 10.4172/2161-069X.1000205
  • Peer Reviewed
• [Journal Article] A rare polymorphic variant of NBS1 reduces DNA repair activity and elevates chromosomal instability (2014)
  • Author(s): Yamamoto, Y., Miyamoto M., Tatsuda D., Kubo M., Nakagama H., Nakamura Y., Satoh H., Matsuda K., Watanabe T. and Ohta T.
  • Journal Title: Cancer Res Volume: 74 Pages: 3707-3715
  • DOI: 10.1158/0008-5472.CAN-13-3037
  • Peer Reviewed
• [Journal Article] Generation of human induced pluripotent stem (Ips) cells in serum- and feeder-free defined culture and TGF-Betal regulation of pluripotency (2014)
  • Author(s): Yamasaki, S., Taguchi Y., Shimamoto A., Mukasa H., Tahara H. and Okamoto T.
  • Journal Title: PLoS One Volume: 9 Pages: e87151
  • DOI: 10.1371/journal.pone.0087151
  • Peer Reviewed
• [Journal Article] Activation of Rheb, but not of mTORC1, impairs spine synapse morphogenesis in tuberous sclerosis complex (2014)
  • Author(s): Yasuda, S., Sugiura H., Katsurabayashi S., Shimada T., Tanaka H., Takasaki K., Iwasaki K., Kobayashi T., Hino O. and Yamagata K.
  • Journal Title: Sci Rep Volume: 4 Pages: 5155
  • DOI: 10.1038/srep05155
  • Peer Reviewed
• [Journal Article] Decreased amyloid-beta Pathologies by intracerebral loading of glycosphingolipid-enriched exosomes in Alzheimer model mice (2014)
  • Author(s): Yuyama, K., Sun H., Sakai S., Mitsutake S., Okada M., Tahara H., Furukawa J., Fujitani N., Shinohara Y. and Igarashi Y.
  • Journal Title: J Biol Chem Volume: 289 Pages: 24488-24498
  • DOI: 10.1074/jbc.M114.577213
  • Peer Reviewed
• [Journal Article] Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk (2014)
  • Author(s): Zhang, B., Jia W.H., Matsuda K., Kweon S.S., Matsuo K., Xiang Y.B., Shin A., Jee S.H., Kim D.H., Cai Q., Long J., Shi J., Wen W., Takahashi A., Matsuda F., Genetics, Epidemiology of Colorectal Cancer Consortium, Colorectal Transdisciplinary Study, Colon Cancer Family Registry, Hosono S., et al.
  • Journal Title: Nat Genet Volume: 46 Pages: 533-542
  • DOI: 10.1038/ng.2985
  • Peer Reviewed
• [Journal Article] Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians (2014)
  • Author(s): Zhang, B., Jia W.H., Matsuo K., Shin A., Xiang Y.B., Matsuda K., Jee S.H., Kim D.H., Cheah P.Y., Ren Z., Cai Q., Long J., Shi J., Wen W., Yang G., Ji B.T., Pan Z.Z., Matsuda F., Kubo M., Hosono S., et al.
  • Journal Title: Int J Cancer Volume: 135 Pages: 948-955
  • DOI: 10.1002/ijc.28733
  • Peer Reviewed
• [Journal Article] Burden of total and cause-specific mortality related to tobacco smoking among adults aged ≥ 45 years in Asia : a pooled analysis of 21 cohorts (2014)
  • Author(s): Zheng, W., McLerran D.F., Rolland B.A., Fu Z., Boffetta P., Tsugane S., Irie F., Tamakoshi A., Shu X.O., Ozasa K., Nishino Y., Tsuji I., Tanaka H., Sawada N., Ohishi W., Kakizaki M., Watanabe T., Oze I., Sugawara Y., Matsuo K., et al.
  • Journal Title: PLoS Med Volume: 11 Pages: e1001631
  • DOI: 10.1371/journal.Pmed.1001631
  • Peer Reviewed
• [Journal Article] クルクミンによるaryl hydrocarbon receptor(AhR)を介した発癌抑制機構 (2014)
  • Author(s): 井手久満、陸彦、杉浦正一郎、堀内明、古謝将之、中島晶子、井上正浩、野間康央、北村香介、常盤紫野、斎藤恵介、吉井隆、磯谷周治、山口雷藏、武藤智、堀江重郎
  • Journal Title: 日本腎泌尿器科疾患予防医学研究会誌 Volume: 22 Pages: 35-37
• [Journal Article] 統計家の行動基準の策定-背景と今後の課題 (2014)
  • Author(s): 佐藤恵子、岩崎学、菅波秀規、佐藤俊哉、椿広計
  • Journal Title: 計量生物学 Volume: 35 Pages: 37-53
  • DOI: 10.5691/jjb.35.37
  • Peer Reviewed
• [Journal Article] バイオバンクにおける同意撤回の自由と不帰投点(Point of No Return) (2014)
  • Author(s): 松井健志、會澤久仁子、玉腰暁子
  • Journal Title: 臨床薬理 Volume: 45 Pages: 17-23
  • DOI: 10.3999/jscpt.45.17
  • Peer Reviewed
• [Journal Article] 前立腺癌におけるがん幹細胞研究(特集去勢抵抗性前立腺癌 : 基礎と臨床の最新研究動向)--(前立腺癌の最新情報) (2014)
  • Author(s): 西田幸代、舛森直哉
  • Journal Title: 日本臨床 Volume: 72 Pages: 2229-2233
• [Journal Article] バイオバンク (2014)
  • Author(s): 増井徹
  • Journal Title: シリーズ生命倫理学 Volume: 11「遺伝子と医療」 Pages: 188-203
  • Description: (丸善出版)
• [Journal Article] ヒトゲノム研究の規制について : ゲノム情報の利用に焦点をあてて (2014)
  • Author(s): 増井徹
  • Journal Title: Organ Biology Volume: 21 Pages: 16-23
  • DOI: 10.11378/organbio.21.16
• [Journal Article] 遺伝子診断の未来と罠 (2014)
  • Author(s): 増井徹、齋藤加代子、菅野純夫
  • Journal Title: こころの科学 Volume: 増刊 Pages: 1-156
  • Description: (日本評論社)
• [Journal Article] 日本人閉経女性における肥満と骨質に関する検討(第15回日本骨粗鬆症学会) (2014)
  • Author(s): 尾崎悦子、栗山長門、松井大輔
  • Journal Title: オステオポローシスジャパン : 日本骨粗鬆症学会雑誌 Volume: 22 Pages: 465-468
  • Peer Reviewed
• [Journal Article] HTLV-1 induces a Thl-like state in CD4+CCR4+T cells (2014)
  • Author(s): N. Araya, T. Sato, H. Ando, U. Tomaru, M. Yoshida, A. Coler-Reilly, N. Yagishita, J. Yamauchi, A. Hasegawa, M. Kannagi, Y. Hasegawa, K. Takahashi, Y. Kunitomo, Y. Tanaka, T. Nakajima, K. Nishioka, A. Utsunomiya, S. Jacobson, Y. Yamano
  • Journal Title: J Clin Invest Volume: 124 Issue: 8 Pages: 3431-42
  • DOI: 10.1172/JCI75250
  • Peer Reviewed
• [Journal Article] Antitumor effects of bevacizumab in a microenvironment-dependent human adult T-cell leukemia/lymphoma mouse model (2014)
  • Author(s): Mori, F., Ishida, T., Ito, A., Sato, F., Masaki, A., Narita, T., Suzuki, S., Yamada, T., Takino, H., Ri, M., Kusumoto, S., Komatsu, H., Hishizawa, M., Imada, K., Takaori-Kondo, A., Niimi, A., Ueda, R., Inagaki, H. & Iida, S.
  • Journal Title: European journal of haematology Volume: 92 Pages: 219-228
  • DOI: 10.1111/ejh.12231
  • Peer Reviewed
• [Journal Article] Reactivation of hepatitis B virus in a patient with adult T-cell leukemia-lymphoma receiving the anti-CC chemokine receptor 4 antibody mogamulizumab (2014)
  • Author(s): Nakano, N., Kusumoto, S., Tanaka, Y., Ishida, T., Takeuchi, S., Takatsuka, Y., Akinaga, S., Mizokami, M., Ueda, R. & Utsunomiya, A.
  • Journal Title: Hepatology research : the official journal of the Japan Society of Hepatology Volume: 44 Pages: 354-357
  • DOI: 10.1111/hepr.12117
  • Peer Reviewed
• [Journal Article] HTLV-1 bZIP factor-specific CD4 T cell responses in adult T cell leukemia/lymphoma patients after allogeneic hematopoietic stem cell transplantation (2014)
  • Author(s): Narita, T., Ishida, T., Masaki, A., Suzuki, S., Ito, A., Mori, F., Yamada, T., Ri, M., Kusumoto, S., Komatsu, H., Miyazaki, Y., Takatsuka, Y., Utsunomiya, A., Niimi, A., Iida, S. & Ueda, R.
  • Journal Title: Journal of immunology Volume: 192 Pages: 940-947
  • DOI: 10.4049/jimmunol.1301952
  • Peer Reviewed
• [Journal Article] Prognostic impact of microRNA-145 down-regulation in adult T-cell leukemia/lymphoma (2014)
  • Author(s): Xia, H., Yamada, S., Aoyama, M., Sato, F., Masaki, A., Ge, Y., Ri, M., Ishida, T., Ueda, R., Utsunomiya, A., Asai, K. & Inagaki, H.
  • Journal Title: Human pathology Volume: 45 Pages: 1192-1198
  • DOI: 10.1016/j.humpath.2014.01.017
  • Peer Reviewed
• [Journal Article] HTLV-1 proviral integration sites differ between asymptomatic carriers and patients with HAM/TSP (2014)
  • Author(s): Niederer HA, Laydon DJ, Melamed A, Elemans M, Asquith B, Matsuoka M, Bangham CR
  • Journal Title: Virology J Volume: 11 Pages: 172
  • DOI: 10.1186/1743-422X-11-172
  • Peer Reviewed
• [Journal Article] A critical role for IL-17RB signaling in HTLV-1 Tax-induced NF-κB activation and T-cell transformation (2014)
  • Author(s): Lavorgna A, Matsuoka M, Harhaj EW
  • Journal Title: PLoS Pathogens Volume: 10 Pages: e1004418
  • DOI: 10.1371/journal.ppat.1004418
  • Peer Reviewed
• [Journal Article] The role of HTLV-1 clonality, proviral structure and genomic integration site in adult T cell leukemia/lymphoma (2014)
  • Author(s): Cook LB, Melamed A, Niederer H, Valganon M, Laydon D, Foroni L, Taylor GP, Matsuoka M, Bangham CR
  • Journal Title: Blood Volume: 123 Pages: 3925-3931
  • DOI: 10.1182/blood-2014-02-553602
  • Peer Reviewed
• [Journal Article] Development of T cell lymphoma in HTLV-1 bZIP factor and Tax double transgenic mice (2014)
  • Author(s): Zhao, T, Satou Y and Matsuoka M
  • Journal Title: Arch Virol Volume: 159 Pages: 1849-1856
  • DOI: 10.1007/s00705-014-2099-y
  • Peer Reviewed
• [Journal Article] Controlling leucine-zipper partner recognition in cells through modifications of a-g interactions (2014)
  • Author(s): Azuma Y, Kukenshöner T, Ma G, Yasunaga JI, Imanishi M, Arndt KM, Matsuoka M, and Futaki S
  • Journal Title: Chem. Commun. Volume: 50 Pages: 6364-6367
  • DOI: 10.1039/c4cc00555d
  • Peer Reviewed
• [Journal Article] HTLV-1 bZIP factor suppresses apoptosis by attenuating the function of Fox03a and altering its localization (2014)
  • Author(s): Tanaka-Nakanishi A, Yasunaga J-I, Takai K and Matsuoka M
  • Journal Title: Cancer Res Volume: 74 Pages: 188-200
  • DOI: 10.1158/0008-5472.CAN-13-0436
  • Peer Reviewed
• [Journal Article] Human T-cell leukemia virus type 1 and Foxp3 expression : viral strategy in vivo (2014)
  • Author(s): Miyazato P and Matsuoka M
  • Journal Title: Int Immunol Volume: 26 Pages: 419-425
  • DOI: 10.1093/intimm/dxu048
  • Peer Reviewed
• [Journal Article] Cytotoxic T lymphocyte lysis of HTLV-1 infected cells is limited by weak HBZ protein expression, but non-specifically enhanced on induction of Tax expression (2014)
  • Author(s): Rowan AG, Suemori K, Fujiwara H, Yasukawa M, Tanaka Y, Taylor GP, Bangham C
  • Journal Title: Retrovirology Volume: 11 Issue: 1 Pages: 116
  • DOI: 10.1186/s12977-014-0116-6
  • Peer Reviewed
• [Journal Article] Downregulation of proapoptotic Bim augments IL-2-independent T-cell transformation by human T-cell leukemia virus type-1 Tax (2014)
  • Author(s): Higuchi M, Takahashi M, Tanaka Y, Fujii M
  • Journal Title: Cancer Med Volume: 3 Issue: 6 Pages: 1605-14
  • DOI: 10.1002/cam4.329
  • Peer Reviewed
• [Journal Article] The neutralizing function of the anti-HTLV-1 antibody is essential in preventing in vivo transmission of HTLV-1 to human T cells in NOD-SCID/gammac null (NOG) mice (2014)
  • Author(s): Saito M, Tanaka R, Fujii H, Kodama A, Takahashi Y, Matsuzaki T, Takashima H, Tanaka Y
  • Journal Title: Retrovirology Volume: 11 Issue: 1 Pages: 74
  • DOI: 10.1186/s12977-014-0074-z
  • Peer Reviewed
• [Journal Article] Epigenetic deregulation of Ellis Van Creveld confers robust Hedgehog signaling in adult T-cell leukemia (2014)
  • Author(s): Takahashi R, Yamagishi M, Nakano K, Yamochi T, Yamochi T, Fujikawa D, Nakashima M, Tanaka Y, Uchimaru K, Utsunomiya A, Watanabe T
  • Journal Title: Cancer Sci Volume: 105 Issue: 9 Pages: 1160-9
  • DOI: 10.1111/cas.12480
  • Peer Reviewed
• [Journal Article] Epigenetic modification of the FoxP3 TSDR in HAM/TSP decreases the functional suppression of Tregs (2014)
  • Author(s): Anderson MR, Enose-Akahata Y, Massoud R, Ngouth N, Tanaka Y, Oh U, Jacobson S
  • Journal Title: J Neuroimmune Pharmacol Volume: 9 Issue: 4 Pages: 522-32
  • DOI: 10.1007/s11481-014-9547-z
  • Peer Reviewed
• [Journal Article] Elimination of human T cell leukemia virus type-l-infected cells by neutralizing and antibody-dependent cellular cytotoxicity-inducing antibodies against human t cell leukemia virus type-1 envelope gp46 (2014)
  • Author(s): Tanaka Y, Takahashi Y, Tanaka R, Kodama A, Fujii H, Hasegawa A, Kannagi M, Ansari AA, Saito M
  • Journal Title: AIDS Res Hum Retroviruses Volume: 30 Issue: 6 Pages: 542-52
  • DOI: 10.1089/AID.2013.0214
  • Peer Reviewed
• [Journal Article] HTLV-1キャリアが産生するウイルス構造蛋白質に対する抗体と末梢血中のプロウイルス量に関する解析 (2014)
  • Author(s): 井上由紀子, 守田麻衣子, 後藤信代, 相良康子, 入田和男, 矢持忠徳, 渡邉俊樹, 岩永正子, 浜口功, 清川博之
  • Journal Title: 日本輸血細胞治療学会誌 Volume: 60 Issue: 6 Pages: 592-599
  • Peer Reviewed
• [Journal Article] Development and validation of a new high-throughput method to investigate the clonality of HTLV-l-infected cells based on provirus integration sites (2014)
  • Author(s): Firouzi S, Lopez Y, Suzuki Y, Nakai K, Sugano S, Yamochi T, Watanabe T
  • Journal Title: Genome Med Volume: 6 Issue: 6 Pages: 46
  • DOI: 10.1186/gm568
  • Peer Reviewed
• [Journal Article] CADM1 expression and stepwise downregulation of CD7 are closely associated with clonal expansion of HTLV-1-infected cells in adult T-cell leukemia/lymphoma (2014)
  • Author(s): Kobayashi S, Nakano K, Watanabe E, Ishigaki T, Ohno N, Yuji K, Oyaizu N, Asanuma S, Yamagishi M, Yamochi T, Watanabe N, Tojo A, Watanabe T, Uchimaru K
  • Journal Title: Clin Cancer Res Volume: 20 Issue: 11 Pages: 2851-2861
  • DOI: 10.1158/1078-0432.CCR-13-3169
  • Peer Reviewed
• [Journal Article] High level of serum soluble interleukin-2 receptor at transplantation predicts poor outcome of allogeneic stem cell transplantation for adult T-cell leukemia (2014)
  • Author(s): Shigematsu A, Kobayashi N, Yasui H, Shindo M, Kakinoki Y, Koda K, Iyama S, Kuroda H, Tsutsumi Y, Imamura M, Teshima T
  • Journal Title: Biol Blood Marrow Transplant Volume: 20 Pages: 801-805
  • DOI: 10.1016/j.bbmt.2014.02.014
  • Peer Reviewed
• [Journal Article] Epstein-Barr virus-infected cells in IgG4-related lymphadenopathy with comparison to extranodal IgG4-related disease (2014)
  • Author(s): Takeuchi M, Sato Y, Yasui H, Ozawa H, Ohno K, Takata K, Iwaki N, Orita Y, Asano N, Nakamura S, Swerdlow SH, Yoshino T
  • Journal Title: Am J Surg Pathol Volume: 38 Pages: 946-955
  • DOI: 10.1097/PAS.0000000000000206
  • Peer Reviewed
• [Journal Article] Cancer-associated fibroblast-targeted strategy enhances antitumor immune responses in the dendritic cell-based vaccine (2014)
  • Author(s): Ohshio Y, Teramoto K, Hanaoka J, Tezuka N, Itoh Y, Asai T, Daigo Y, Ogasawara K
  • Journal Title: Cancer Sci
  • DOI: 10.1111/cas.12584
  • Description: [Epub ahead of print]
  • Peer Reviewed
• [Journal Article] Clinicopathological features and EGFR gene mutation status in elderly patients with resected non-small-cell lung cancer (2014)
  • Author(s): Nishii T, Yokose T, Miyagi Y, Daigo Y, Ito H, Isaka T, Imai K, Murakami S, Kondo T, Saito H, Oshita F, Yamada K, Matsukuma S, Tsuboi M, Nakayama H, Masuda M
  • Journal Title: BMC Cancer Volume: 14 Pages: 610
  • DOI: 10.1186/1471-2407-14-610
  • Peer Reviewed
• [Journal Article] Identification of a nuclear protein LRRC42 involved in lung pulmonary carcinogenesis (2014)
  • Author(s): Fujitomo T, Daigo Y, Matsuda K, Ueda K, Nakamura Y
  • Journal Title: Int J Oncol Volume: 45 Pages: 147-56
  • DOI: 10.3892/ijo.2014.2418
  • Peer Reviewed
• [Journal Article] Identification of immunogenic LY6K long peptide encompassing both CD4+ and CD8+ T-cell epitopes and eliciting CD4+ T-cell immunity in patients with malignant disease (2014)
  • Author(s): Tomita Y, Yuno A, Tsukamoto H, Senju S, Kuroda Y, Hirayama M, Imamura Y, Yatsuda J, Mohammad Abu Sayem, Irie A, Hamada A, Jono H, Yoshida K, Tsunoda T, Daigo Y, Kohrogi H, Yoshitake Y, Nakamura Y, Shinohara M, Nishimura Y.
  • Journal Title: Oncoimmunology Volume: 3 Pages: e28100
  • DOI: 10.4161/onci.28100
  • Peer Reviewed
• [Journal Article] Cell division cycle-associated protein 1 overexpression is essential for the malignant potential of colorectal cancers. (2014)
  • Author(s): Kobayashi Y, Takano A, Miyagi Y, Tsuchiya E, Sonoda H, Shimizu T, Okabe H, Tani T, Fujiyama Y, Daigo Y.
  • Journal Title: Int J Oncol Volume: 44 Pages: 69-77
  • DOI: 10.3892/ijo.2013.2177
  • Peer Reviewed
• [Journal Article] Proteomic Analysis of Proteins Related to Prognosis of Lung Adenocarcinoma. (2014)
  • Author(s): Okayama A, Miyagi Y, Oshita F, Nishi M, Nakamura Y, Nagashima Y, Akimoto K, Ryo A, Hirano H.
  • Journal Title: J Proteome Res Volume: 13 Issue: 11 Pages: 4686-94
  • DOI: 10.1021/pr4012969
  • Peer Reviewed
• [Journal Article] SIRT1 expression is associated with a poor prognosis, whereas DBC1 is associated with favorable outcomes in gastric cancer (2014)
  • Author(s): Noguchi A, Kikuchi K, Zheng H, Takahashi H, Miyagi Y, Aoki I, Takano Y.
  • Journal Title: Cancer Med Volume: 3 Issue: 6 Pages: 1553-61
  • DOI: 10.1002/cam4.310
  • Peer Reviewed
• [Journal Article] Angiomodulin, a marker of cancer vasculature, is upregulated by vascular endothelial growth factor and increases vascular permeability as a ligand of integrin αvβ3 (2014)
  • Author(s): Komiya E, Sato H, Watanabe N, Ise M, Higashi S, Miyagi Y, Miyazaki K
  • Journal Title: Cancer Med Volume: 3 Issue: 3 Pages: 537-49
  • DOI: 10.1002/cam4.216
  • Peer Reviewed
• [Journal Article] Lung adenocarcinoma subtypes definable by lung development-related miRNA expression profiles in association with clinicopathologic features (2014)
  • Author(s): Arima C, Kajino T, Tamada Y, Imoto S, ShimadaY, Nakatochi, M, Suzuki M, Isomura H, Yatabe Y, Yamaguchi T, Yanagisawa K, Miyano S, Takahashi T.
  • Journal Title: Carcinogenesis Volume: 35 Pages: 2224-2231
  • DOI: 10.1093/carcin/bgu127
  • Peer Reviewed
• [Journal Article] Expression of chromobox homolog 7 (CBX7) is associated with poor prognosis in ovarian clear cell adenocarcinoma via TRAIL-induced apoptotic pathway regulation. (2014)
  • Author(s): Shinjo K, Yamashita Y, Yamamoto E, Akatsuka S, Uno N, Kamiya A, Niimi K, Sakaguchi Y, Nagasaka T, Takahashi T, Shibata K, Kajiyama H, Kikkawa F, Toyokuni S.
  • Journal Title: Int J Cancer Volume: 135 Pages: 308-318
  • DOI: 10.1002/ijc.28692
  • Peer Reviewed
• [Journal Article] Tumor-derived Interleukin-1 promotes lymphangiogenesis and lymph node metastasis through M2-type macrophages (2014)
  • Author(s): Watari K, Shibata T, Kawahara A, Sata K, Nabeshima H, Shinoda A, Abe H, Azuma K, Murakami Y, Izumi, H, Takahashi T, Kage M, Kuwano M, Ono M.
  • Journal Title: PLoS ONE Volume: 9 Pages: e999568
  • DOI: 10.1371/journal.pone.0099568
  • Peer Reviewed
• [Journal Article] Cancer-promoting role of adipocytes in asbestos-induced mesothelial carcinogenesis through dysregulated adipocytokine production (2014)
  • Author(s): Chew SH, Okazaki Y, Nagai H, Misawa N, Akatsuka S, Yamashita K, Jiang L, Yamashita Y, Noguchi M, Hosoda K, Sekido Y, Takahashi T, Toyokuni S
  • Journal Title: Carcinogenesis Volume: 35 Pages: 164-172
  • DOI: 10.1093/carcin/bgt267
  • Peer Reviewed
• [Journal Article] Multimodal Effects of Small Molecule ROCK and LIMK Inhibitors on Mitosis, and Their Implication as Anti-Leukemia Agents (2014)
  • Author(s): Oku Y, Tareyanagi C, Takaya S, Osaka S, Ujiie H, Yoshida K, Nishiya N, Uehara Y.
  • Journal Title: PLoS One Volume: 9 Pages: e92402
  • DOI: 10.1371/journal.pone.0092402
  • Peer Reviewed
• [Journal Article] A zebrafish chemical suppressor screening identifies small molecule inhibitors of the Wnt/β-catenin pathway (2014)
  • Author(s): Nishiya N, Oku Y, Kumagai Y, Sato Y, Yamaguchi E, Sasaki A, Shoji M, Ohnishi Y, Okamoto H, Uehara Y.
  • Journal Title: Chemistry & Biology Volume: 12 Pages: 530-540
  • DOI: 10.1016/j.chembiol.2014.02.015
  • Peer Reviewed
• [Journal Article] Total synthesis of burkholdacs A and B and 5, 6, 20-tri-epi-burkholdac A : HDAC inhibition and antiproliferative activity (2014)
  • Author(s): Fukui Y, Narita K, Dan S, Yamori T, Ito A, Yoshida M, Katoh T
  • Journal Title: Eur. J. Med. Chem. Volume: 76 Pages: 301-313
  • DOI: 10.1016/j.ejmech.2014.02.044
  • Peer Reviewed
• [Journal Article] 5-Lipoxygenase and CysLTl regulate EGF-induced cell migration through Tiaml upregulation and Racl activation (2014)
  • Author(s): Magi S, Takemoto Y, Kobayashi H, Kasamatsu M, Akita T, Tanaka A, Takano K, Tashiro E, Igarashi Y, Imoto M
  • Journal Title: Cancer Sci Volume: 105 Pages: 290-296
  • DOI: 10.1111/cas.12340
  • Peer Reviewed
• [Journal Article] TRIBl supports prostate tumorigenesis and tumor-propagating cell survival by regulation of endoplasmic reticulum chaperone expression (2014)
  • Author(s): Mashima T, Soma-Nagae T, Migita T, Kinoshita R, Iwamoto A, Yuasa T, Yonese J, Ishikawa Y, Seimiya H
  • Journal Title: Cancer Res Volume: 74 Pages: 4888-4897
  • DOI: 10.1158/0008-5472.CAN-13-3718
  • Peer Reviewed
• [Journal Article] Inhibition of ATP citrate lyase induces triglyceride accumulation with altered fatty acid composition in cancer cells (2014)
  • Author(s): Migita T, Okabe S, Ikeda K, Igarashi S, Sugawara S, Tomida A, Soga T, Taguchi R, Seimiya H
  • Journal Title: Int J Cancer Volume: 135 Pages: 37-47
  • DOI: 10.1002/ijc.28652
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• [Journal Article] Xanthohumol suppresses oestrogen-signalling in breast cancer through the inhibition of BIG3-PHB2 interactions (2014)
  • Author(s): Yoshimaru T, Komatsu M, Tashiro E, Imoto M, Osada H, Miyoshi Y, Honda J, Sasa M, Katagiri T
  • Journal Title: Sci Rep Volume: 4 Pages: 7355
  • DOI: 10.1038/srep07355
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• [Journal Article] A small compound targeting TACC3 revealed its different spatiotemporal contributions for spindle assembly in cancer cells (2014)
  • Author(s): Yao R, Kondoh Y, Natsume Y, Yamanaka H, Inoue M, Toki H, Takagi R, Shimizu T, Yamori T, Osada H, Noda T
  • Journal Title: Oncogene Volume: 33 Issue: 33 Pages: 4242-4252
  • DOI: 10.1038/onc.2013.382
  • Peer Reviewed
• [Journal Article] Regulation of Tissue Factor Pathway Inhibitor-2 (TFPI-2) Expression by Lysine-Specific Demethylase 1 and 2 (LSD1 and LSD2) (2014)
  • Author(s): Mino K, Nishimura S, Ninomiya S, Tujii H, Matsumori Y, Tsuchida M, Hosoi M, Koseki K, Wada S, Hasegawa M, Sasaki R, Murakami-Yamaguchi Y, Narita H, Suzuki T, Miyata N, Mizukami T
  • Journal Title: Biosci Biotechnol Biochem Volume: 78 Issue: 6 Pages: 1010-1017
  • DOI: 10.1080/09168451.2014.910104
  • Peer Reviewed
• [Journal Article] Array-based genome-wide RNAi screening to identify shRNAs that enhance p53-related apoptosis in human cancer cells (2014)
  • Author(s): Idogawa M, Ohashi T, Sugisaka J, Sasaki Y, Suzuki H, Tokino T
  • Journal Title: Oncotarget Volume: 5 Issue: 17 Pages: 7540-7548
  • Peer Reviewed
• [Journal Article] Forkhead transcription factor FOXF1 is a novel target gene of the p53 family and regulates cancer cell migration and invasiveness (2014)
  • Author(s): Tamura M, Sasaki Y, Koyama R, Takeda K, Idogawa M, Tokino T
  • Journal Title: Oncogene Volume: 33 Issue: 40 Pages: 4837-4846
  • DOI: 10.1038/onc.2013.427
  • Peer Reviewed
• [Journal Article] Identification and analysis of large non-coding RNAs regulated by p53 family members through a genome-wide analysis of p53-binding sites (2014)
  • Author(s): Idogawa M, Ohashi T, Sasaki Y, Maruyama R, Kashima L, Suzuki H, Tokino T
  • Journal Title: Human Molecular Genetics Volume: 23 Issue: 11 Pages: 2847-2857
  • DOI: 10.1093/hmg/ddt673
  • Peer Reviewed
• [Journal Article] Silencing of microRNA-122 is an early event during hepatocarcinogenesis from non-alcoholic steatohepatitis (2014)
  • Author(s): Takaki Y, Saito Y, Takasugi A, Toshimitsu K, Yamada S, Muramatsu T, Kimura M, Sugiyama K, Suzuki H, Arai E, Ojima H, Kanai Y, Saito H
  • Journal Title: Cancer Sci Volume: 105 Pages: 1254-1260
  • DOI: 10.1111/cas.12498
  • Peer Reviewed
• [Journal Article] Mesenchymal stem cells cancel azoxymethane-induced tumor initiation. (2014)
  • Author(s): Nasuno M, Arimura Y, Nagaishi K, Isshiki H, Onodera K, Nakagaki S, Watanabe S, Idogawa M, Yamashita K, Naishiro Y, Adachi Y, Suzuki H, Fujimiya M, Imai K, Shinomura Y.
  • Journal Title: STEM CELLS Volume: 32(4) Pages: 913-925
  • DOI: 10.1002/stem.1594.
  • Peer Reviewed
• [Journal Article] Low serum level of high-sensitivity C-reactive protein in a Japanese subject with MODY3. (2014)
  • Author(s): Ohki T, Utsu Y, Morita S, Karim M.F., Sato Y, Yoshizawa T, Yamamura K, Yamada K, Kasayama S, Yamagata K.
  • Journal Title: J. Diabetes Invest. Volume: in press. Pages: －
  • Peer Reviewed
• [Journal Article] Autophagy regulation in the pancreatic acinar cells is independent of epidermal growth factor receptor signaling. (2014)
  • Author(s): Ozaki, N., Fukuchi, Y., Tomiyoshi, S., Uehara1, H., Ida, S., Wang, J., Kimi Araki, K., Sibilia, M., Baba, H., and Yamamura, K., and Ohmuraya, M.
  • Journal Title: Biochem. Biophysic. Res. Comm. Volume: in press. Pages: －
  • Peer Reviewed
• [Journal Article] mTORC1 controls the cell cycle of the earliest T-lineage-committed cells and its inactivation eradicates acute lymphoblastic T-cell leukemia in mice. (2014)
  • Author(s): Hoshii, T., Kasada, A., Hatakeyama, N., Ohtani,M., Tadokoro, Y., Naka, K., Ikenoue, T., Ikawa, T., Kawamoto, H., Araki, K., Yamamura, K., Matsuda, S. and Hirao, A.
  • Journal Title: Proc. Natl. Acad. Sci. USA. Volume: in press. Pages: －
  • Peer Reviewed
• [Journal Article] Rescue In Vitro Fertilization Method for Legacy Stock of Frozen Mouse Sperm. (2014)
  • Author(s): Nakagata, N., Takeo, T., Fukumoto, K., Haruguchi, Y., Kondo, T., Takeshita, Y., Nakamuta, Y., Umeno, T. and Tsuchiyama, S.
  • Journal Title: J Reprod Dev Volume: 60 Pages: 167-170
  • Peer Reviewed
• [Journal Article] Preclinical evaluation of an O(6)-methylguanine-DNA methyltransferase-siRNA/liposome complex administered by convection-enhanced delivery to rat and porcine brains. (2014)
  • Author(s): Tsujiuchi T., Natsume A., Motomura K., Kondo G., Ranjit M., Hachisu R., Sugimura I., Tomita S., Takehara I., Woolley M., Barua N.U., Gill S.S., Bienemann A.S., Yamashita Y., Toyokuni S., Wakabayashi T.
  • Journal Title: Am J Transl Res. eCollection 2014 Volume: 6 Pages: 169-78
  • Peer Reviewed
• [Journal Article] A Novel Transgenic Mouse Model Carrying Human Tribbles Related Protein 3 (TRB3) Gene and Its Site Specific Phenotype. (2014)
  • Author(s): Y. Sakai, K. Fukamachi, M. Futakuchi, I. Miyoshi, H. Tsuda, M. Suzui, H. Hayashi.
  • Journal Title: Biol. Pharm. Bull. Volume: in press. Pages: -
  • Peer Reviewed
• [Journal Article] Importance of the progesterone receptor (PR) and the epidermal growth factor receptor (EGFR), but not the estrogen receptor (ER), for chemically induced lung carcinogenesis in female A/J mice. (2014)
  • Author(s): Kishi S., Yokohira M., Yamakawa K., Saoo K., Imaida K.
  • Journal Title: Oncol. Lett. Volume: in press Pages: －
  • Peer Reviewed
• [Journal Article] Cross-boundary Cancer Studies at the University of Tokyo: View from the world of science and reason. (2014)
  • Author(s): Akaza H.
  • Journal Title: Japanese journal of clinical oncology Volume: 44 Suppl 1 Pages: i3-5
  • DOI: 10.1093/jjco/hyt228
  • Peer Reviewed
• [Journal Article] Cross-boundary cancer studies at the University of Tokyo: Surviving cancer in Asia: introduction. (2014)
  • Author(s): Akaza H, Kawahara N.
  • Journal Title: Japanese journal of clinical oncology Volume: 44 Suppl 1 Pages: i1-2
  • DOI: 10.1093/jjco/hyt231
  • Peer Reviewed
• [Journal Article] Japanese Cancer Association Meeting UICC International session--what is cost-effectiveness in cancer treatment? (2014)
  • Author(s): Akaza H, Kawahara N, Roh JK et al.
  • Journal Title: Asian Pacific journal of cancer prevention : APJCP Volume: 15 Pages: 3-10
  • DOI: 10.7314/APJCP.2014.15.1.3
  • Peer Reviewed
• [Journal Article] Associations of dietary patterns with metabolic syndrome and insulin resistance: a cross-sectional study in a Japanese population. (2014)
  • Author(s): Arisawa K, Uemura H, Yamaguchi M et al.
  • Journal Title: J Med Invest Volume: in press Pages: -
  • Peer Reviewed
• [Journal Article] Associations between hOGG1 Ser326Cys polymorphism and increased body mass index and fasting glucose in the Japanese general population. (2014)
  • Author(s): Hara M, Nakamura K, Nanri H, KIta Y, Suzuki S, Ohnaka K, Mikami H, Kubo M, Tanaka H et al.
  • Journal Title: Journal of epidemiology / Japan Epidemiological Association Volume: in press Pages: -
  • Peer Reviewed
• [Journal Article] Retrospective analysis of large-scale research screening of construction workers for the early diagnosis of mesothelioma. (2014)
  • Author(s): Hirohashi T, Igarashi K, Abe M, Hino O et al.
  • Journal Title: Molecular and clinical oncology Volume: 2 Pages: 26-30
  • DOI: 10.3892/mco.2013.197
  • Peer Reviewed
• [Journal Article] GCK, GCKR polymorphisms and risk of chronic kidney disease in Japanese individuals: data from the J-MICC Study. (2014)
  • Author(s): Hishida A, Takashima N, Turin TC, Wakai K, Suzuki S, Mikami H, Ohnaka K, Kubo M, Tanaka H, Kita Y et al.
  • Journal Title: Journal of nephrology Volume: 27 Pages: 143-149
  • DOI: 10.1007/s40620-013-0025-0
  • Peer Reviewed
• [Journal Article] ERC/mesothelin is expressed in human gastric cancer tissues and cell lines. (2014)
  • Author(s): Ito T, Kajino K, Abe M, Hino O et al.
  • Journal Title: Oncology reports Volume: 31 Pages: 27-33
  • DOI: 10.3892/or.2013.2803
  • Peer Reviewed
• [Journal Article] Comparison of plasma levels of nutrients-related biomarkers among Japanese populations in Tokyo, Japan, in Sao Paulo, Brazil, and in Hawaii, USA. (2014)
  • Author(s): Iwasaki M, Franke A, Hamada G, Tsugane S et al.
  • Journal Title: European Journal of Cancer Prevention Volume: in press Pages: in press
  • Peer Reviewed
• [Journal Article] C-ERC/mesothelin provokes lymphatic invasion of colorectal adenocarcinoma. (2014)
  • Author(s): Kawamata F, Homma S, Kamachi H, Hino O et al.
  • Journal Title: Journal of gastroenterology Volume: 49 Pages: 81-92
  • DOI: 10.1007/s00535-013-0773-6
  • Peer Reviewed
• [Journal Article] ABCG2 dysfunction causes hyperuricemia due to both renal urate underexcretion and renal urate overload. (2014)
  • Author(s): Matsuo H, Nakayama A, Sakiyama M, Wakai K et al.
  • Journal Title: Scientific reports Volume: 4 Pages: 3755
  • DOI: 10.1038/srep03755
  • Peer Reviewed
• [Journal Article] Plasma amino acid profiles are associated with biomarkers of breast cancer risk in premenopausal Japanese women. (2014)
  • Author(s): Nagata C, Wada K, Tsuji M et al.
  • Journal Title: Cancer causes & control : CCC Volume: 25 Pages: 143-149