がん研究分野の特性等を踏まえた支援活動

2014 Fiscal Year Annual Research Report

• Project Area: がん研究分野の特性等を踏まえた支援活動
• Project/Area Number: 221S0001
• Research Institution: The University of Tokyo
• Principal Investigator: 今井 浩三 東京大学, 医科学研究所, 特任教授 (60117603)
• Co-Investigator(Kenkyū-buntansha): 中村 卓郎 公益財団法人がん研究会, がん研究所・発がん研究部, 副所長 (00180373) ; 山村 研一 熊本大学, 生命資源研究・支援センター, シニア教授 (90115197) ; 田中 英夫 愛知県がんセンター(研究所), ・疫学・予防部, 部長 (60470168) ; 神奈木 真理 東京医科歯科大学, 大学院医歯学総合研究科, 教授 (80202034) ; 醍醐 弥太郎 東京大学, 医科学研究所, 特任教授 (30345029)
• Project Period (FY): 2010-04-01 – 2016-03-31
• Keywords: 若手支援 / 国際研究者交流 / 遺伝子改変マウス / 病理形態学 / ゲノムコーホート研究 / 個別化がん予防 / 次世代分子解析技術 / アカデミア創薬

Outline of Annual Research Achievements

総括支援 : 公開シンポジウム、ワークショップ(日独、日韓、がん若手 : 82名参加・発表)、青少年市民公開講座開催。がん研究読本④・⑤をネット出版。
個体レベルでのがん研究支援 : Tg作製4件、ゲノム編集関連61件、ES関連103件、個体でのアレル変換42件、微生物モニタリング427検体、遺伝モニタリング2732検体、凍結保存50系統、病理形態学31件、ワークショップ1回支援した。
がん疫学・予防研究支援 : 10万1千名の研究者提供生体試料を用いた研究支援。テロメア長測定支援5、aberrant crypt fosiをバイオマーカーとした大腸癌予防介入試験支援6、肥満と肝発癌関連実験モデル作成等がん予防への研究支援を行った。HTLV-1研究支援 : 患者検体の免疫解析、プロウイルス量測定、抗ATLワクチン療法や抗CCR4抗体療法の後方支援、HTLV-1関連単クロン抗体の製造管理・供与、患者登録システムJSPFAD(9000検体以上)の維持運営、検体供与を行った。
臨床診断研究支援 : 組織・FFPE975、血清・DNA1583のがん試料収集、4研究者に計379を提供した。膵臓がん258例からなる組織アレイを構築。各種診断法検証支援で論文13編に貢献した。組織バンク、技術支援と啓蒙講演を実施した。
化学療法基盤支援 : 依頼化合物102点の作用機序・分子標的阻害活性評価、延べ714件。阻害剤キット・化合物ライブラリー整備拡充・提供227枚。薬効関連遺伝子発現・新薬開発情報等のDB整備を拡充し公開した。創薬関連シンポジウムを2回開催した。
ゲノム・エピゲノム解析支援 : がん関連の409遺伝子変異等について17研究者から376検体を解析、DNAメチル化解析等について7研究者から延べ1490検体の解析、マイクロRNA発現解析等について4研究者から延べ270検体の解析を行った。

Current Status of Research Progress

1: Research has progressed more than it was originally planned.

Reason

各支援活動とも、計画に沿って順調に支援を続けているが、以下の活動では計画以上の進展を示した。若手研究者支援では、「がん特定領域研究」時代以来の継続による積極的取組が功を奏し、がん研究を初めとする医学生物学系においてリーダーとなる人材が輩出するようになってきたが、本年度もこの流れは継続している。国際交流活動ではフランス、韓国、ドイツとの二国間ワークショッップを本年度実施する等、相互交流がより活発となり、共同研究や人材交流が一層盛んになっている。広報活動として、がん研究の現状を一般にわかりやすく解説したネット出版物「がん研究読本」も巻を5まで重ね、好評を得ている。また、高校生を対象としたキャンサーセミナーを盛岡市にて実施した。がん疫学・予防支援活動では、多施設共同コホート研究で10万人のリクルートを達成した。
一方、研究者のネットワーク構築を背景として、臨床診断研究支援を初めとするがん研究者への支援から世界をリードするがん研究の論文成果が着実に挙げられている。さらに、脳・ゲノム支援活動との連携促進による生命科学系3分野としての活動が着実に進行し、これまでに3回の合同シンポジウムを開催した。特にモデル動物に関する情報交換を行って共通のデータベース立ち上げへの道を開くとともに、技術面での意見交換も行った。平成24年度から追加されたゲノム・エピゲノム解析支援も活動が進展し、患者サンプル及びモデル動物の遺伝子異常解析支援が順調に行われている。

Strategy for Future Research Activity

平成22～26年度の支援活動をより強固に継続するとともに、若手研究者を中心として、科研費採択課題に対する、より広い分野の研究を対象とした積極的な支援を行う。がん若手研究シンポジウム及び、日仏・日韓の2国間がんワークショップは本年も開催を予定しているが、今後の発展を見据えて育成・交流の成果を挙げたい。個体レベルの研究支援においては、CRISPR/Cas9に代表される最新テクノロジーを利用したモデル動物開発を既に開始しているので、その成績を見極めるとともに、がんと再生・幹細胞研究、脳研究との連携を推進する。また、個体レベルのがん研究ワークショップを引き続き開催して、支援の成果を公表する。がん疫学・予防支援では、コホート研究で得られた試料のがん研究への利用を倫理面での評価を行いながら更に推進する。臨床診断研究支援では、プロテオーム解析や組織アレイのさらなる充実化を図り、がん研究者へのヒト検体を用いた解析を支援することで、世界レベルの研究成果の増産を目指す。化学療法基盤支援活動では、がん研究分野以外への支援も視野に入れた化合物の評価・スクリーニングを進める。がんゲノム・エピゲノム解析支援活動では、上述のように支援体制が整備されたので、ヒト検体・モデル動物検体に対する、遺伝子変異パネルの解析を推進する。
また、生命科学系3分野間の連携を一層促進し、今後の自然科学系の具体的な推進策を立案する。特に、本支援活動が、ボトムアップ支援と最先端技術を開発と一体化した体制を構築するよう検討を進める。

Research Products

• [Journal Article] Impact of metallothionein gene polymorphisms on the risk of lung cancer in a Japanese population (2016)
  • Author(s): Nakane H, Hirano M, Ito H, Hosono S, Oze I, Matsuda F, Tanaka H, Matsuo K.
  • Journal Title: Mol Carcinog Volume: 54(S1) Pages: E122-E128
  • DOI: 10.1002/mc.22198
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes (2016)
  • Author(s): Matsuo H, Yamamoto K, Nakaoka H, Nakayama A, Sakiyama M, Chiba T, Takahashi A, Nakamura T, Nakashima H, Takada Y, Danjoh I, Shimizu S, Abe J, Kawamura Y, Terashige S, Ogata H, Tatsukawa S, Yin G, Okada R, Morita E, Naito M, Tokumasu A, et al.
  • Journal Title: Ann Rheum Dis Volume: 75 Pages: 652-659
  • DOI: 10.1136/annrheumdis-2014-206191
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Schwann cells contribute to neurodegeneration of transthyretin amyloidosis. (2015)
  • Author(s): Murakami, T., Sango, K., Watabe, K., Niimi, N., Takaku, S., Li, Z, Yamamura, K., Sunada, Y.
  • Journal Title: J. Neurochem. Volume: 134 Pages: 66-74
  • DOI: 10.1111/jnc.13068
  • Peer Reviewed
• [Journal Article] Roles of hepatic glucokinase in intertissue metabolic communication: examination of novel liver-specific glucokinase knockout mice. (2015)
  • Author(s): Hayashi, H., Sato, Y., Li, Z., Yamamura, K, Yoshizawa, T. and Yamagata, K.
  • Journal Title: Biochem. Biophys. Res. Commun. Volume: 460 Pages: 727-732
  • DOI: 10.1016/j.bbrc.2015.03.097
  • Peer Reviewed
• [Journal Article] Meikin is a conserved regulator of meiosis-I-specific kinetochore function. (2015)
  • Author(s): Kim, J., Ishiguro, K., Nambu, A., Akiyoshi, B., Yokobayashi, S., Kagami, A., Ishiguro, T., Pendas, AM., Takeda, N., Sakakibara, Y., Kitajima, TS., Tanno, Y., Sakuno, T. and Watanabe, Y.
  • Journal Title: Nature Volume: 517 Pages: 466-471
  • DOI: 10.1038/nature14097
  • Peer Reviewed
• [Journal Article] Cigarette smoke inhalation and risk of lung cancer: a case-control study in a large Japanese population. (2015)
  • Author(s): Fukumoto K, Ito H, Matsuo K, Tanaka H, Yokoi K, Tajima K, Takezaki T.
  • Journal Title: Eur J Cancer Prev Volume: 24(3) Pages: 195-200
  • DOI: 10.1097/CEJ.0000000000000034
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Panitumumab for locally advanced head and neck squamouse-cell carcinoma (2015)
  • Author(s): Ishiki H, Iwase S, Shimada N, Chiba T, Imai K
  • Journal Title: Lancet Oncology Volume: 16 Issue: 4 Pages: e156
  • DOI: 10.1016/S1470-2045(15)70101-4
  • Peer Reviewed
• [Journal Article] Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis (2015)
  • Author(s): Mitsuhashi K, Nosho K, Sukawa Y, Matsunaga Y, Ito M, Kurihara H, Kanno S, Igarashi H, Naito T, Adachi Y, Tachibana M, Tanuma T, Maguchi H, Shinohara T, Hasegawa T, Imamura M, Kimura Y, Hirata K, Maruyama R, Suzuki H, Imai K, Yamamoto H, Shinomura Y
  • Journal Title: Oncotarget
  • Description: 【掲載確定】 in press
  • Peer Reviewed
• [Journal Article] Microsatellite instability : an update (2015)
  • Author(s): Yamamoto H, Imai K
  • Journal Title: Archives of Toxicology
  • Description: 【掲載確定】 in press
  • Peer Reviewed
• [Journal Article] Screening of drugs to treat 8p11 myeloproliferative syndrome using patient-derived induced pluripotent stem cells with fusion gene CEP110-FGFR1 (2015)
  • Author(s): Yamamoto S, Otsu M, Matsuzaka E, Konishi C, Takagi H, Hanada S, Mochizuki S, Nakauchi H, Imai K, Tsuji K, Ebihara Y
  • Journal Title: Plos One
  • Description: 【掲載確定】 in press
  • Peer Reviewed
• [Journal Article] Clinicopathological and molecular characteristics of serrated lesions in Japanese elderly patients (2015)
  • Author(s): Nosho K, Igarashi H, Ito M, Mitsuhashi K, Kurihara H, Kanno S, Yoshii S, Mikami M, Takahashi H, Kusumi T, Hosokawa M, Sukawa Y, Adachi Y, Hasegawa T, Okita K, Hirata K, Maruyama R, Suzuki H, Imai K, Yamamoto H, Shinomura Y
  • Journal Title: Digestion Volume: 91 Issue: 1 Pages: 57-63
  • DOI: 10.1159/000368820
  • Peer Reviewed
• [Journal Article] Contextual niche signals towards colorectal tumor progression by mesenchymal stem cell in the mouse xenograft model (2015)
  • Author(s): Nakagaki S, Arimura Y, Nagaishi K, Isshiki H, Nasuno M, Watanabe S, Idogawa M, Yamashita K, Naishiro Y, Adachi Y, Suzuki H, Fujimiya M, Imai K, Shinomura Y
  • Journal Title: J Gastroenterol
  • Description: 【掲載確定】 Epub ahead of print
  • Peer Reviewed
• [Journal Article] 抗体医薬 (2015)
  • Author(s): 安井寛, 今井浩三
  • Journal Title: DDS研究30年 Volume: PHARMA TECH JAPAN 臨時増刊号,31(2) Pages: 94-101
  • Peer Reviewed
• [Journal Article] 抗体治療 特集「DDSがもたらした新しい臨床の風景」 (2015)
  • Author(s): 佐々木茂, 篠村恭久, 今井浩三
  • Journal Title: Drug Delivery System Volume: 30 Issue: 1 Pages: 16-24
  • Peer Reviewed
• [Journal Article] CHF5074(CSP-1103)stabilizes human transthyretin in mice humanized at the transthyretin and retinol-binding protein loci (2015)
  • Author(s): Mu, Y., Jin, S., Shen, J., Sugano, A., Takaoka, Y., Qiang, L., Imbimbo, B.P., Yamamura, K. and Li, Z.
  • Journal Title: FEBS letters
  • DOI: 10.1016/j.febslet.2015.02.020
  • Description: in press
  • Peer Reviewed
• [Journal Article] Requirement of DLG1 for cardiovascular development and tissue elongation during cochlear, enteric, and skeletal development : possible role in convergent extension (2015)
  • Author(s): Iizuka-Kogo, A., Senda, T., Akiyama, T., Shimomura, A., Nomura, R., Hasegawa, Y., Yamamura, K., Kogo, H., Sawai, N. and Matsuzaki, T.
  • Journal Title: Plos One
  • Description: in press
  • Peer Reviewed
• [Journal Article] Determining c-Myb protein levels can isolate functional hematopoietic stem cell subtypes (2015)
  • Author(s): Sakamoto, H, Takeda, N, Arai, F, Hosokawa, K, Garcia, P, Suda, T, Frampton, J, Ogawa, M
  • Journal Title: Stem Cells Volume: 2 Pages: 479-490
  • DOI: 10.1002/stem.1855
  • Peer Reviewed
• [Journal Article] Cysteine analogs with a free thiol group promote fertilization by reducing disulfide bonds in the Zona Pellucida of mice (2015)
  • Author(s): Takeo, T., Horikoshi, Y., Nakao, S., Sakoh, K., Ishizuka, Y., Tsutsumi, A., Fukumoto, K., Kondo, T., Haruguchi, Y., Takeshita, Y., Nakamuta, Y., Tsuchiyama, S. and Nakagata, N.
  • Journal Title: Biol. Reprod. Volume: 92(4)90 Pages: 1-7
  • DOI: 10.1095/biolreprod.114.125443
  • Peer Reviewed
• [Journal Article] Minimal inflammogenicity of pristine single-wall carbon nanotubes (2015)
  • Author(s): Toyokuni, S, Jiang, L, Kitaura, R and Shinohara, S
  • Journal Title: Nagoya J Med Sci Volume: 77 Pages: 195-202
  • DOI: 10.3389/fphar.2014.00200
  • Peer Reviewed
• [Journal Article] Percutaneous Carbon Dioxide Treatment using a Gas Mist Generator Enhances the Collateral Blood Flow in the Ischemic Hindlimb (2015)
  • Author(s): Izumi, Y, Yamaguchi, T, Yamazaki, T, Yamashita, N, Nakamura, Y, Shiota, M, Tanaka, M, Sano, S, Osada-Oka, M, Shimada, K, Wanibuchi, H, Miura, K, Yoshiyama, M, Iwao, H
  • Journal Title: J Atheroscler Thromb Volume: 22 Pages: 38-51
  • DOI: 10.5551/jat.23770
  • Peer Reviewed
• [Journal Article] Paraneoplastic Ma Antigen-Like 1 as a Potential Prognostic Biomarker in Human Pancreatic Ductal Adenocarcinoma (2015)
  • Author(s): Kuwae, Y, Kakehashi, A, Wakasa, K, Wei, M, Yamano, S, Ishii, N, Ohsawa, M, Wanibuchi, H
  • Journal Title: Pancreas Volume: 44 Pages: 106-115
  • Peer Reviewed
• [Journal Article] Determination of Hepatotoxicity and Its Underlying Metabolic Basis of 1,2-dichloropropane in Male Syrian Hamsters and B6C3F1 Mice (2015)
  • Author(s): Wei, M, Fujioka, M, Yamano, S, Shimomura, E, Ishii, N, Kakehashi, A, Takeshita, M, Wanibuchi, H
  • Journal Title: Toxicol. Sci
  • Description: in press
  • Peer Reviewed
• [Journal Article] Inhibition of β-catenin and STAT3 with curcumin analog suppresses gastric carcinogenesis in vivo : a novel candidate for gastric cancer treatment (2015)
  • Author(s): Uehara, Y., Inoue, M., Fukuda, K., Yamakoshi, H., Hosoi, Y., Kanda, H., Oshima, M., Iwabuchi, Y., Shibata, H.
  • Journal Title: Gastric Cancer
  • DOI: 10.1007/s10120-014-0434-3
  • Description: in press
  • Peer Reviewed
• [Journal Article] NPT1/SLC17A1 is a renal urate exporter in humans and its common gain-of-function variant decreases the risk of renal underexcretion gout (2015)
  • Author(s): Chiba, T., Matsuo H., Kawamura Y., Nagamori S., Nishiyama T., Wei L., Nakayama A., Nakamura T., Sakiyama M., Takada T., Taketani Y., Suma S., Naito M., Oda T., Kumagai H., Moriyama Y., Ichida K., Shimizu T., Kanai Y. and Shinomiya N.
  • Journal Title: Arthritis Rheumatol Volume: 67 Pages: 281-287
  • DOI: 10.1002/art.38884
  • Peer Reviewed
• [Journal Article] Common variant of ALPK1 is not associated with gout : a replication study (2015)
  • Author(s): Chiba, T., Matsuo H., Sakiyama M., Nakayama A., Shimizu S., Wakai K., Suma S., Nakashima H., Sakurai Y., Shimizu T., Ichida K. and Shinomiya N.
  • Journal Title: Hum Cell Volume: 28 Pages: 1-4
  • DOI: 10.1007/s13577-014-0103-1
  • Peer Reviewed
• [Journal Article] HLA-A SNPs and amino acid variants are associated with nasopharyngeal carcinoma in Malaysian Chinese (2015)
  • Author(s): Chin, Y.M., Mushiroda T., Takahashi A., Kubo M., Krishnan G., Yap L.F., Teo S.H., Lim P.V., Yap Y.Y., Pua K.C., Kamatani N., Nakamura Y., Sam C.K., Khoo A.S., Malaysian N.P.C.S.G. and Ng C.C.
  • Journal Title: Int J Cancer Volume: 136 Pages: 678-687
  • DOI: 10.1002/ijc.29035
  • Peer Reviewed
• [Journal Article] Syndecan-1 responsive microRNA-126 and 149 regulate cell proliferation in prostate cancer (2015)
  • Author(s): Fujii, T., Shimada K., Tatsumi Y., Fujimoto K. and Konishi N.
  • Journal Title: Biochem Biophys Res Commun Volume: 456 Pages: 183-189
  • DOI: 10.1016/j.bbrc.2014.11.056
  • Peer Reviewed
• [Journal Article] Fine-Scale Mapping of the 5q11.2 Breast Cancer Locus Reveals at Least Three Independent Risk Variants Regulating MAP3K1 (2015)
  • Author(s): Glubb, D.M., Maranian M.J., Michailidou K., Pooley K.A., Meyer K.B., Kar S., Carlebur S., O'Reilly M., Betts J.A., Hillman K.M., Kaufmann S., Beesley J., Hopper J.L., Southey M.C., Apicella C., Schmidt M.K., Matsuo K., Ito H., Iwata H., Tanaka H., et al.
  • Journal Title: Am J Hum Genet Volume: 96 Pages: 5-20
  • DOI: 10.1016/j.ajhg.2014.11.009
  • Peer Reviewed
• [Journal Article] Gastric cancer in young vs old Romanian patients : immunoprofile with emphasis on maspin and mena protein reactivity (2015)
  • Author(s): Gurzu, S., Kadar Z., Sugimura H., Bara T., Bara T., Jr., Halmaciu I. and Jung I.
  • Journal Title: APMIS Volume: 123 Pages: 223-233
  • DOI: 10.1111/apm.12347
  • Peer Reviewed
• [Journal Article] Factors Associated With Non-participation in a Face-to-Face Second Survey Conducted 5 Years After the Baseline Survey (2015)
  • Author(s): Hara, M., Shimanoe C., Otsuka Y., Nishida Y., Nanri H., Horita M., Yasukata J., Miyoshi N., Yamada Y., Higaki Y. and Tanaka K.
  • Journal Title: J Epidemiol Volume: 25 Pages: 117-125
  • DOI: 10.2188/jea.JE20140116
  • Peer Reviewed
• [Journal Article] Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci (2015)
  • Author(s): He, M., Xu M., Zhang B., Liang J., Chen P., Lee J.Y., Kubo M., A., Li H., Yang X., Dai J., Liang L., Gui L., Qi Q., Huang J., Okada Y., Takeuchi F., Tanaka T., Yamamoto K., Yokota M., Kato N., et al.
  • Journal Title: Hum Mol Genet Volume: 24 Pages: 1791-1800
  • DOI: 10.1093/hmg/ddu583
  • Peer Reviewed
• [Journal Article] A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese (2015)
  • Author(s): Hirokawa, M., Morita H., Tajima T., Takahashi A., Ashikawa K., Miya F., Shigemizu D., Ozaki K., Sakata Y., Nakatani D., Suna S., Imai Y., Tanaka T., Tsunoda T., Matsuda K., Kadowaki T., Nakamura Y., Nagai R., Komuro I. and Kubo M.
  • Journal Title: Eur J Hum Genet Volume: 23 Pages: 374-380
  • DOI: 10.1038/ejhg.2014.110
  • Peer Reviewed
• [Journal Article] Low FOXA1 expression predicts good response to neo-adjuvant chemotherapy resulting in good outcomes for luminal HER2-negative breast cancer cases (2015)
  • Author(s): Horimoto, Y., Arakawa A., Harada-Shoji N., Sonoue H., Yoshida Y., Himuro T., Igari F., Tokuda E., Mamat O., Tanabe M., Hino O. and Saito M.
  • Journal Title: Br J Cancer Volume: 112 Pages: 345-351
  • DOI: 10.1038/bjc.2014.595
  • Peer Reviewed
• [Journal Article] Genome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians (2015)
  • Author(s): Hwang, J.Y., Sim X., Wu Y., Liang J., Tabara Y., Hu C., Hara K., Takeuchi F., Ong R.T., Ohkubo T., Kim Y.J., Zhang R., Yamauchi T., Katsuya T., Umemura S., Maeda S., Kita Y., Takashima N., Osawa H., Kato N., et al.
  • Journal Title: Diabetes Volume: 64 Pages: 291-298
  • DOI: 10.2337/db14-0563
  • Peer Reviewed
• [Journal Article] Circulating Pigment Epithelium-derived Factor (PEDF) Is Associated with Pathological Grade of Prostate Cancer (2015)
  • Author(s): Ide, H., Yamagishi S., Lu Y., Sakamaki K., Nakajima A., Horiuchi A., Kitamura K., Hisasue S., Muto S., Yamaguchi R. and Horie S.
  • Journal Title: Anticancer Res Volume: 35 Pages: 1703-1708
  • Peer Reviewed
• [Journal Article] B-RAF mutation and accumulated gene methylation in aberrant crypt foci (ACF), sessile serrated adenoma/polyp (SSA/P) and cancer in SSA/P (2015)
  • Author(s): Inoue, A., Okamoto K., Fujino Y., Nakagawa T., Muguruma N., Sannomiya K., Mitsui Y., Takaoka T., Kitamura S., Miyamoto H., Okahisa T., Fujimori T., Imoto I. and Takayama T.
  • Journal Title: Br J Cancer Volume: 112 Pages: 403-412
  • DOI: 10.1038/bjc.2014.545
  • Peer Reviewed
• [Journal Article] Establishment of Tsc2-deficient rat embryonic stem cells (2015)
  • Author(s): Ito, Y., Kawano H., Kanai F., Nakamura E., Tada N., Takai S., Horie S., Arai H., Kobayashi T. and Hino O.
  • Journal Title: Int J Oncol Volume: 46 Pages: 1944-1952
  • DOI: 10.3892/ijo.2015.2913
  • Peer Reviewed
• [Journal Article] Comparison of plasma levels of nutrient-related biomarkers among Japanese populations in Tokyo, Japan, Sao Paulo, Brazil, and Hawaii, USA (2015)
  • Author(s): Iwasaki, M., Franke A.A., Hamada G.S., Miyajima N.T., Sharma S., Ishihara J., Takachi R., Tsugane S. and Le Marchand L.
  • Journal Title: Eur J Cancer Prev Volume: 24 Pages: 155-161
  • DOI: 10.1097/CEJ.0000000000000136
  • Peer Reviewed
• [Journal Article] Comparison of plasma levels of obesity-related biomarkers among Japanese populations in Tokyo, Japan, Sao Paulo, Brazil, and Hawaii, USA (2015)
  • Author(s): Iwasaki, M., Le Marchand L., Franke A.A., Hamada G.S., Miyajima N.T., Sharma S., Yamaji T. and Tsugane S.
  • Journal Title: Eur J Cancer Prev
  • DOI: 10.1097/CEJ.0000000000000123
  • Description: Epub ahead of print
  • Peer Reviewed
• [Journal Article] EVpedia : a community web portal for extracellular vesicles research (2015)
  • Author(s): Kim, D.K., Lee J., Kim S.R., Choi D.S., Yoon Y.J., Kim J.H., Go G., Nhung D., Hong K., Jang S.C., Kim S.H., Park K.S., Kim O.Y., Park H.T., Seo J.H., Aikawa E., Baj-Krzyworzeka M., van Balkom B.W., Tahara H., Youn H., et al.
  • Journal Title: Bioinformatics Volume: 31 Pages: 933-939
  • DOI: 10.1093/bioinformatics/btu741
  • Peer Reviewed
• [Journal Article] Cytological Features of a Variant NUT Midline Carcinoma of the Lung Harboring the NSD3-NUT Fusion Gene : A Case Report and Literature Review (2015)
  • Author(s): Kuroda, S., Suzuki S., Kurita A., Muraki M., Aoshima Y., Tanioka F. and Sugimura H.
  • Journal Title: Case Rep Pathol Volume: 2015 Pages: 572951
  • DOI: 10.1155/2015/572951
  • Peer Reviewed
• [Journal Article] Genome-wide association study identified SNP on 15q24 associated with bladder cancer risk in Japanese population (2015)
  • Author(s): Matsuda, K., Takahashi A., Obara W., Nasu Y., Inoue K., Tamura K., Yamasaki I., Naya Y., Tanikawa C., Namiki M., Tomita Y., Nishiyama H., Kohri K., Deguchi T., Nakagawa M., Yokoyama M., Miki T., Kumon H., Fujioka T., Kubo M., et al.
  • Journal Title: Hum Mol Genet Volume: 24 Pages: 1177-1184
  • DOI: 10.1093/hmg/ddu512
  • Peer Reviewed
• [Journal Article] Serologically Determined Gastric Mucosal Condition Is a Predictive Factor for Osteoporosis in Japanese Men (2015)
  • Author(s): Mizuno, S., Matsui D., Watanabe I., Ozaki E., Kuriyama N. and Watanabe Y.
  • Journal Title: Dig Dis Sci
  • DOI: 10.1007/s10620-015-3576-1
  • Description: Epub ahead of print
  • Peer Reviewed
• [Journal Article] Validity of the food frequency questionnaire in a population with high alcohol consumption in Japan (2015)
  • Author(s): Nakahata, T.N., Takada N.A., Imaeda N., Goto C., Kuwabara H.K., Niimura H., Arai H., Yoshita Y. and Takezaki T.K.
  • Journal Title: Asia Pac J Clin Nutr
  • Description: in press
  • Peer Reviewed
• [Journal Article] Dietary Patterns and Serum Gamma-Glutamyl Transferase in Japanese Men and Women (2015)
  • Author(s): Nanri, H., Hara M., Nishida Y., Shimanoe C., Nakamura K., Higaki Y., Imaizumi T., Taguchi N., Sakamoto T., Horita M., Shinchi K., Kokaze A. and Tanaka K.
  • Journal Title: J Epidemiol
  • DOI: 10.2188/jea.JE20140158
  • Description: in press
  • Peer Reviewed
• [Journal Article] CD44-expressing undifferentiated carcinoma with rhabdoid features of the pancreas : Molecular analysis of aggressive invasion and metastasis (2015)
  • Author(s): Ohmoto, T., Yoshitani N., Nishitsuji K., Takayama T., Yanagisawa Y., Takeya M. and Sakashita N.
  • Journal Title: Pathol Int
  • DOI: 10.1111/pin.12283
  • Description: Epub ahead of print
  • Peer Reviewed
• [Journal Article] Peretinoin after curative therapy of hepatitis C-related hepatocellular carcinoma : a randomized double-blind placebo-controlled study (2015)
  • Author(s): Okita, K., Izumi N., Matsui O., Tanaka K., Kaneko S., Moriwaki H., Ikeda K., Osaki Y., Numata K., Nakachi K., Kokudo N., Imanaka K., Nishiguchi S., Okusaka T., Nishigaki Y., Shiomi S., Kudo M., Ido K., Karino Y., Hayashi N., et al.
  • Journal Title: J Gastroenterol Volume: 50 Pages: 191-202
  • DOI: 10.1007/s00535-014-0956-9
  • Peer Reviewed
• [Journal Article] Cotyledonoid dissecting leiomyoma of the uterus : report of two cases (2015)
  • Author(s): Saeki, H., Suzuki C., Yamasaki S., Hashizume A., Izumi H., Suzuki F., Ishi K., Nojima M. and Hino O.
  • Journal Title: Arch Gynecol Obstet Volume: 291 Pages: 357-361
  • DOI: 10.1007/s00404-014-3406-2
  • Peer Reviewed
• [Journal Article] Association between endometriosis and the interleukin 1A (IL1A) locus (2015)
  • Author(s): Sapkota, Y., Low S.K., Attia J., Gordon S.D., Henders A.K., Holliday E.G., MacGregor S., Martin N.G., McEvoy M., Morris A.P., Takahashi A., Scott R.J., Kubo M., Zondervan K.T., Montgomery G.W. and Nyholt D.R.
  • Journal Title: Hum Reprod Volume: 30 Pages: 239-248
  • DOI: 10.1093/humrep/deu267
  • Peer Reviewed
• [Journal Article] Werner Syndrome-specific induced pluripotent stem cells : recovery of telomere function by reprogramming (2015)
  • Author(s): Shimamoto, A., Yokote K. and Tahara H.
  • Journal Title: Front Genet Volume: 6 Pages: 10
  • DOI: 10.3389/fgene.2015.00010
  • Peer Reviewed
• [Journal Article] Perceived stress and coping strategies in relation to body mass index : cross-sectional study of 12,045 Japanese men and women (2015)
  • Author(s): Shimanoe, C., Hara M., Nishida Y., Nanri H., Otsuka Y., Nakamura K., Higaki Y., Imaizumi T., Taguchi N., Sakamoto T., Horita M., Shinchi K. and Tanaka K.
  • Journal Title: PLoS One Volume: 10 Pages: e0118105
  • DOI: 10.1371/journal.pone.0118105
  • Peer Reviewed
• [Journal Article] The oncological outcome and validation of Japan Cancer of the Prostate Risk Assessment score among men treated with primary androgen-deprivation therapy (2015)
  • Author(s): Shiota, M., Yokomizo A., Takeuchi A., Imada K., Kiyoshima K., Inokuchi J., Tatsugami K. and Naito S.
  • Journal Title: J Cancer Res Clin Oncol Volume: 141 Pages: 495-503
  • DOI: 10.1007/s00432-014-1828-7
  • Peer Reviewed
• [Journal Article] Associations between polymorphisms of interleukin-6 and related cytokine genes and serum liver damage markers : a cross-sectional study in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study (2015)
  • Author(s): Sugimoto, Y., Wakai K., Nakagawa H., Suma S., Sasakabe T., Sakamoto T., Takashima N., Suzuki S., Ogawa S., Ohnaka K., Kuriyama N., Arisawa K., Mikami H., Kubo M., Hosono S., Hamajima N., Tanaka H. and J-Micc Study Group
  • Journal Title: Gene Volume: 557 Pages: 158-162
  • DOI: 10.1016/j.gene.2014.12.025
  • Peer Reviewed
• [Journal Article] Rheb actvation disrupts spine synapse formation through accumulation of syntenin in tuberous sclerosis complex (2015)
  • Author(s): Sugiura H., Y.S., Katsurabayashi S., Kawano H., Endo K., Takasaki K., Iwasaki K., Ichikawa M., Kobayashi T., Hino O. and Yamagata K.
  • Journal Title: Nature Communications Volume: 6 Pages: 6842
  • DOI: 10.1038/ncomms7842
  • Peer Reviewed
• [Journal Article] Urethral toxicity after LDR brachytherapy : experience in Japan (2015)
  • Author(s): Tanaka, N., Asakawa I., Hasegawa M. and Fujimoto K.
  • Journal Title: Brachytherapy Volume: 14 Pages: 131-135
  • DOI: 10.1016/j.brachy.2014.09.009
  • Peer Reviewed
• [Journal Article] A potential function for neuronal exosomes : sequestering intracerebral amyloid-beta peptide (2015)
  • Author(s): Yuyama, K. Sun H., Usuki S. Sakai S. Hanamatsu H., Mioka T. Kimura N. Okada N. Tahara H. Furukawa J. Fujitani N. Shinohara Y. and Igarashi Y.
  • Journal Title: FEBS Lett Volume: 589 Pages: 84-88
  • DOI: 10.1016/j.febslet.2014.11.027
  • Peer Reviewed
• [Journal Article] Clinical outcomes of a novel therapeutic vaccine with Tax peptide-pulsed dendritic cells for adult T cell leukaemia/lymphoma in a pilot study. (2015)
  • Author(s): Suehiro, Y., Hasegawa, A., Iino, T., Sasada, A., Watanabe, N., Matsuoka, M., Takamori, A., Tanosaki, R., Utsunomiya, A., Choi, I., Fukuda, T., Miura, O., Takaishi, S., Teshima, T., Akashi, K., Kannagi, M., Uike, N., Okamura, J.
  • Journal Title: British journal of haematology
  • DOI: 10.1111/bjh.13302
  • Description: 印刷中
  • Peer Reviewed
• [Journal Article] Involvement of double-stranded RNA-dependent protein kinase and antisenseviral RNA in the constitutive NFkappaB activation in adult T-cell leukemia/lymphoma cells (2015)
  • Author(s): Kinpara, S., Ito, S., Takahata, T., Saitoh, Y., Hasegawa, A., Kijiyama, M., Utsunomiya, A., Masuda, M., Miyazaki, Y., Matsuoka, M., Nakamura, M., Yamaoka, S., Masuda, T., Kannagi, M.
  • Journal Title: Leukemia
  • DOI: 10.1038/leu.2015.1
  • Description: 印刷中
  • Peer Reviewed
• [Journal Article] Fatal reactivation of hepatitis B virus infection in a patient with adult T-cell leukemia-lymphoma receiving the anti-CC chemokine receptor 4 antibody mogamulizumab (2015)
  • Author(s): Ifuku, H., Kusumoto, S., Tanaka, Y., Totani, H., Ishida, T., Okada, M., Murakami, S., Mizokami, M., Ueda, R. & lida, S.
  • Journal Title: Hepatology research : the official journal of the Japan Society of Hepatology
  • DOI: 10.1111/hepr.12513
  • Description: 印刷中
  • Peer Reviewed
• [Journal Article] Dose-intensified chemotherapy alone or in combination with mogamulizumab in newly diagnosed aggressive adult T-cell leukaemia-lymphoma : a randomized phase II study (2015)
  • Author(s): Ishida, T., Jo, T., Takemoto, S., Suzushima, H., Uozumi, K., Yamamoto, K., Uike, N., Saburi, Y., Nosaka, K., Utsunomiya, A., Tobinai, K., Fujiwara, H., Ishitsuka, K., Yoshida, S., Taira, N., Moriuchi, Y., Imada, K., Miyamoto, T., Akinaga, S., Tomonaga, M. & Ueda, R.
  • Journal Title: British journal of haematology
  • DOI: 10.1111/bjh.13338
  • Description: 印刷中
  • Peer Reviewed
• [Journal Article] Prognostic significance of tryptophan catabolism in adult T-cell leukemia/lymphoma (2015)
  • Author(s): Masaki, A., Ishida, T., Maeda, Y., Suzuki, S., Ito, A., Takino, H., Ogura, H., Totani, H., Yoshida, T., Kinoshita, S., Narita, T., Ri, M., Kusumoto, S., Inagaki, A., Komatsu, H., Niimi, A., Ueda, R., Utsunomiya, A., Inagaki, H. & Iida, S.
  • Journal Title: Clinical cancer research : an official journal of the American Association for Cancer Research
  • DOI: 10.1158/1078-0432.CCR-14-2275
  • Description: 印刷中
  • Peer Reviewed
• [Journal Article] CD30-positive primary bone marrow lymphoma mimicking Hodgkin lymphoma (2015)
  • Author(s): Suzuki T, Kusumoto S, Masaki A, Ishida T, Inagaki H, Iida S, Mori F
  • Journal Title: Int J Hematol Volume: 101 Issue: 2 Pages: 109-11
  • DOI: 10.1007/s12185-014-1714-8
  • Peer Reviewed
• [Journal Article] Reactivation of hepatitis B virus (HBV) infection in adult T-cell leukemia-lymphoma patients with resolved HBV infection following systemic chemotherapy (2015)
  • Author(s): Totani, H., Kusumoto, S., Ishida, T., Masuda, A., Yoshida, T., Ito, A., Ri, M., Komatsu, H., Murakami, S., Mizokami, M., Ueda, R., Niimi, A., Inagaki, H., Tanaka, Y. & Iida, S.
  • Journal Title: International journal of hematology Volume: 101 Pages: 398-404
  • DOI: 10.1007/s12185-015-1750-z
  • Peer Reviewed
• [Journal Article] TCFl and LEFl act as T-cell intrinsic HTLV-1 antagonists by targeting Tax (2015)
  • Author(s): Ma G, Yasunaga J-I, Akari H, Matsuoka M
  • Journal Title: Proc. Natl. Acad. Sci. U.S.A. Volume: 112 Pages: 2216-2221
  • DOI: 10.1073/pnas.1419198112
  • Peer Reviewed
• [Journal Article] Human T-cell leukemia virus type 1 Tax oncoprotein represses the expression of the BCL11B tumor suppressor in T-cells (2015)
  • Author(s): Takachi T, Takahashi M, Takahashi-Yoshita M, Higuchi M, Obata M, Mishima Y, Okuda S, Tanaka Y, Matsuoka M, Saitoh A, Green P, Fujii M
  • Journal Title: Cancer Sci
  • DOI: 10.1111/cas.12618
  • Description: in press
  • Peer Reviewed
• [Journal Article] Re-evaluation of screening of plasma positive for human T-cell leukemia virus type 1 using a luciferase immunoprecipitation system in blood donors (2015)
  • Author(s): Furuta RA, Ma G, Matsuoka M, Otani S, Matsukura H, Hirayama F
  • Journal Title: Transfusion
  • DOI: 10.1111/trf.12911
  • Description: in press
  • Peer Reviewed
• [Journal Article] Visualization of HTLV-1-specific cytotoxic T lymphocytes in the spinal cords of patients with HTLV-1-associated myelopathy/tropical spastic paraparesis (2015)
  • Author(s): Matsuura E, Kubota R, Tanaka Y, Takashima H, Izumo S
  • Journal Title: J Neuropathol Exp Neurol Volume: 74 Issue: 1 Pages: 2-14
  • DOI: 10.1097/NEN.0000000000000141
  • Peer Reviewed
• [Journal Article] Separate cellular localizations of human T-lymphotropic virus 1 (HTLV-1) Env and glucose transporter type 1 (GLUT1) are required for HTLV-1 Env-mediated fusion and infection (2015)
  • Author(s): Maeda Y, Terasawa H, Tanaka Y, Mitsuura C, Nakashima K, Yusa K, Harada S
  • Journal Title: J Virol Volume: 89 Issue: 1 Pages: 502-11
  • DOI: 10.1128/JVI.02686-14
  • Peer Reviewed
• [Journal Article] Mogamulizumab, an anti-CCR4 antibody, targets human T-lymphotropic virus type 1-infected CD8+ and CD4+ T cells to treat associated myelopathy (2015)
  • Author(s): Yamauchi J, Coler-Reilly A, Sato T, Araya N, Yagishita N, Ando H, Kunitomo Y, Takahashi K, Tanaka Y, Shibagaki Y, Nishioka K, Nakajima T, Hasegawa Y, Utsunomiya A, Kimura K, Yamano Y
  • Journal Title: J Infect Dis Volume: 211 Issue: 2 Pages: 238-48
  • DOI: 10.1093/infdis/jiu438
  • Peer Reviewed
• [Journal Article] Advanced HTLV-1 carriers and early-stage indolent ATLs are indistinguishable based on CADM1 positivity in flow cytometry (2015)
  • Author(s): Kobayashi S, Watanabe E, Ishigaki T, Ohno N, Yuji K, Nakano K, Yamochi T, Watanabe N, Tojo A, Watanabe T, Uchimaru K
  • Journal Title: Cancer Sci
  • DOI: 10.1111/cas.12639
  • Description: Epub ahead of print
  • Peer Reviewed
• [Journal Article] Identification of TL-Oml, an ATL Cell Line, as a Reference Material for Human T-Lymphotropic Virus 1 Quantitative PCR (2015)
  • Author(s): Kuramitsu M, Okuma K, Yamagishi M, Yamochi T, Firouzi S, Momose H, Mizukami T, Takizawa K, Araki K, Sugamura K, Yamaguchi K, Watanabe T, Hamaguchi I
  • Journal Title: J Clin Microbiol Volume: 53 Issue: 2 Pages: 587-596
  • DOI: 10.1128/JCM.02254-14
  • Peer Reviewed
• [Journal Article] Epigenetic Heterogeneity in HIV-1 Latency Establishment (2015)
  • Author(s): Matsuda Y, Kobayashi-Ishihara M, Fujikawa D, Ishida T, Watanabe T, Yamagishi M
  • Journal Title: Sci Rep Volume: 5 Pages: 7701
  • DOI: 10.1038/srep07701
  • Peer Reviewed
• [Journal Article] SMK-17, a MEK1/2-specific inhibitor, selectively induces apoptosis in β-catenin-mutated tumors. (2015)
  • Author(s): Kiga M, Nakayama A, Shikata Y, Sasazawa Y, Murakami R, Nakanishi T, Tashiro E, Imoto M.
  • Journal Title: Sci Rep. Volume: 5 Pages: 8155
  • DOI: 10.1038/srep08155
  • Peer Reviewed
• [Journal Article] Basal expression of insulin-like growth factor l receptor determines intrinsic resistance of cancer cells to a phosphatidylinositol 3-kinase inhibitor ZSTK474 (2015)
  • Author(s): Isoyama S, Kajiwara G, Tamaki N, Okamura M, Yoshimi H, Nakamura N, Kawamura K, Nishimura Y, Namatame N, Yamori T, Dan S
  • Journal Title: Cancer Sci Volume: 106 Issue: 2 Pages: 171-178
  • DOI: 10.1111/cas.12582
  • Peer Reviewed
• [Journal Article] Design, synthesis and structure-activity relationships of 1-ethylpyrazole-3-carboxamide as novel HIF-1 inhibitors (2015)
  • Author(s): Yasuda Y, Arakawa T, Nawata Y, Shimada S, Oishi S, Fujii N, Nishimura S, Hattori A, Kakeya H
  • Journal Title: Bioorg. Med. Chem. Volume: 23 Pages: 1776-1787
  • DOI: 10.1016/j.bmc.2015.02.038
  • Peer Reviewed
• [Journal Article] Association of microRNA-31-5p with clinical efficacy of anti-EGFR therapy in patients with metastatic colorectal cancer (2015)
  • Author(s): Igarashi H, Kurihara H, Mitsuhashi K, Ito M, Okuda H, Kanno S, Naito T, Yoshii S, Takahashi H, Kusumi T, Hasegawa T, Sukawa Y, Adachi Y, Okita K, Hirata K, Imamura Y, Baba Y, Imai K, Suzuki H, Yamamoto H, Nosho K, Shinomura Y
  • Journal Title: Ann Surg Oncol
  • DOI: 10.1245/s10434-014-4264-7
  • Description: Epub ahead of print
  • Peer Reviewed
• [Journal Article] Mesenchymal stem cells cancel azoxymethane-induced tumor initiation (2014)
  • Author(s): Nasuno M, Arimura Y, Nagaishi K, Isshiki H, Onodera K, Nakagaki S, Watanabe S, Idogawa M, Yamashita K, Naishiro Y, Adachi Y, Suzuki H, Fujimiya M, Imai K, Shinomura Y
  • Journal Title: STEM CELLS Volume: 32 Issue: 4 Pages: 913-25
  • DOI: 10.1002/stem.1594
  • Peer Reviewed
• [Journal Article] MicroRNA-31 expression in relation to BRAF mutation, CpG island methylation and colorectal continuum in serrated lesions (2014)
  • Author(s): Ito M, Mitsuhashi K, Igarashi H, Nosho K, Naito T, Yoshii S, Takahashi H, Fujita M, Sukawa Y, Yamamoto E, Takahashi T, Adachi Y, Nojima M, Sasaki Y, Tokino T, Baba Y, Maruyama R, Suzuki H, Imai K, Yamamoto H, Shinomura Y
  • Journal Title: Int J Cancer Volume: 135 Issue: 11 Pages: 2507-15
  • DOI: 10.1002/ijc.28920
  • Peer Reviewed
• [Journal Article] The effect of IGF-I receptor blockade for human esophageal squamous cell carcinoma and adenocarcinoma (2014)
  • Author(s): Adachi Y, Ohashi H, Imsumran A, Yamamoto H, Matsunaga Y, Taniguchi H, Nosho K, Suzuki H, Sasaki Y, Arimura Y, Carbone DP, Imai K, Shinomura Y
  • Journal Title: Tumor Biol Volume: 35 Issue: 2 Pages: 973-85
  • DOI: 10.1007/s13277-013-1131-2
  • Peer Reviewed
• [Journal Article] Analysis of DNA methylation in bowel lavage fluid for detection of colorectal cancer (2014)
  • Author(s): Harada T, Yamamoto E, Yamano H, Nojima M, Maruyama R, Kumegawa K, Ashida M, Yoshikawa K, Kimura T, Harada E, Takagi R, Tanaka Y, Aoki H, Nishizono M, Nakaoka M, Tuyada A, Niinuma T, Kai M, Shimoda K, Shinomura Y, Sugai T, Imai K, Suzuki H
  • Journal Title: Cancer Prevention Research (Philadelphia, Pa.) Volume: 7 Issue: 10 Pages: 1002-10
  • DOI: 10.1158/1940-6207.CAPR-14-0162
  • Peer Reviewed
• [Journal Article] Overview and Future prospect of “Promotion plan for the platform of human resource development for cancer” (2014)
  • Author(s): Imai K.
  • Journal Title: Juntendo Medical Journal Volume: 60 Issue: 3 Pages: 234-237
  • Peer Reviewed
• [Journal Article] IGF2 differentially methylated region hypomethylation in relation to pathological and molecular features of serrated lesions (2014)
  • Author(s): Naito T, Nosho K, Ito M, Igarashi H, Mitsuhashi K, Yoshii S, Aoki H, Nomura M, Sukawa Y, Yamamoto E, Adachi Y, Takahashi H, Hosokawa M, Fujita M, Takenouchi T, Maruyama R, Suzuki H, Baba Y, Imai K, Yamamoto H, Ogino S, Shinomura Y
  • Journal Title: World J Gastroenterol Volume: 20 Issue: 29 Pages: 10050-61
  • DOI: 10.3748/wjg.v20.i29.10050
  • Peer Reviewed
• [Journal Article] DNA synthesis inhibitors for the treatment of gastrointestinal cancer (2014)
  • Author(s): Yasui H, Tsurita G, Imai K
  • Journal Title: Expert Opin Pharmacother Volume: 15 Issue: 16 Pages: 2361-72
  • DOI: 10.1517/14656566.2014.958074
  • Peer Reviewed
• [Journal Article] The Use of Bone Marrow Stromal Cells (Bone Marrow-Derived Multipotent Mesenchymal Stromal Cells) for Alveolar Bone Tissue Engineering : Basic Science to Clinical Translation (2014)
  • Author(s): Kagami H, Agata H, Inoue M, Asahina I, Tojo A, Yamashita N, Imai K
  • Journal Title: Tissue Engineering Part B : Reviews Volume: 20 Issue: 3 Pages: 229-232
  • DOI: 10.1089/ten.TEB.2013.0578
  • Peer Reviewed
• [Journal Article] Association of microRNA-31-5p with clinical efficacy of anti-EGFR therapy in patients with metastatic colorectal cancer (2014)
  • Author(s): Igarashi H, Kurihara H, Mitsuhashi K, Ito M, Okuda H, Kanno S, Naito T, Yoshii S, Takahashi H, Kusumi T, Hasegawa T, Sukawa Y, Adachi Y, Okita K, Hirata K, Imamura Y, Baba Y, Imai K, Suzuki H, Yamamoto H, Nosho K, Shinomura Y
  • Journal Title: Annals of Surgical Oncology
  • Description: Epub ahead of print
  • Peer Reviewed
• [Journal Article] 総説 橋渡し研究の展開と我が国の医療 (2014)
  • Author(s): 今井浩三
  • Journal Title: 東京都病院薬剤師会雑誌 Volume: 63 Issue: 2 Pages: 5-8
  • Peer Reviewed
• [Journal Article] 人口動態に基づいた日本医療の未来予測-高齢多死社会の到来, 特集「超高齢者に対する外科治療の問題点」 (2014)
  • Author(s): 湯地晃一郎, 井元清哉, 山口類, 宮野悟, 上昌広, 今井浩三
  • Journal Title: 南江堂臨床雑誌「外科」 Volume: 76 Issue: 5 Pages: 457-463
  • Peer Reviewed
• [Journal Article] 大規模コホートを用いた大腸癌のノンコーディングRNA発現異常と生活習慣の分子疫学的解析 (2014)
  • Author(s): 能正勝彦, 五十嵐央祥, 伊藤美樹, 三橋慧, 栗原弘義, 菅野伸一, 内藤崇史, 須河安恭敬, 松永康孝, 足立靖, 野島正寛, 今井浩三, 丸山玲緒, 鈴木拓, 山本博幸, 篠村恭久
  • Journal Title: 日本癌病態治療研究会誌 Volume: 20 Issue: 1 Pages: 60-63
  • Peer Reviewed
• [Journal Article] がんエピゲノム異常を理解し、応用し、そして制御するために (2014)
  • Author(s): 鈴木拓, 今井浩三
  • Journal Title: 実験医学 Volume: 32 Issue: 19 Pages: 3024-3029
  • Peer Reviewed
• [Journal Article] Generation and analysis of serine protease inhibitor Kazal type 3-cre driver mice (2014)
  • Author(s): Sakata, K., Ohmuraya, M., Araki, K., Suzuki, C., Ida, S., Hashimoto, D., Wang, J., Uchiyama, Y., Baba, H. and Yamamura, K.
  • Journal Title: Exp. Anim. Volume: 63 Pages: 45-53
  • Peer Reviewed
• [Journal Article] Autophagy regulation in the pancreatic acinar cells is independent of epidermal growth factor receptor signaling (2014)
  • Author(s): Ozaki, N., Fukuchi, Y., Tomiyoshi, S., Ueharal, H., Ida, S., Wang, J., Kimi Araki, K., Sibilia, M., Baba, H., Yamamura, K. and Ohmuraya, M
  • Journal Title: Biochem. Biophysic. Res. Comm. Volume: 446 Pages: 224-230
  • DOI: 10.1016/j.bbrc.2014.02.111
  • Peer Reviewed
• [Journal Article] Low serum level of high-sensitivity C-reactive protein in a Japanese subject with MODY3 (2014)
  • Author(s): Ohki T, Utsu Y, Morita S, Karim M.F., Sato Y, Yoshizawa T, Yamamura K, Yamada K, Kasayama S, Yamagata K
  • Journal Title: J. Diabetes Invest Volume: 5 Pages: 513-516
  • DOI: 10.1111/jdi.12237
  • Peer Reviewed
• [Journal Article] Genetic analysis of the role of Alx4 in the coordination of lower body and external genitalia formation (2014)
  • Author(s): Matsumaru, D., Haraguchi, R., Moon, A.M., Satoh, Y., Nakagata, N., Yamamura, K., Takahashi, N., Kitazawa, S. and Yamada, G.
  • Journal Title: Eur. J. Human Genet Volume: 22 Pages: 350-357
  • DOI: 10.1038/ejhg.2013.160
  • Peer Reviewed
• [Journal Article] mTORCl controls the cell cycle of the earliest T-lineage-committed cells and its inactivation eradicates acute Iymphoblastic T-cell leukemia in mice (2014)
  • Author(s): Hoshii, T., Kasada, A., Hatakeyama, N., Ohtani, M., Tadokoro, Y., Naka, K., Ikenoue, T., Ikawa, T., Kawamoto, H., Araki, K., Yamamura, K., Matsuda, S. and Hirao, A.
  • Journal Title: Proc. Natl. Acad. Sci. USA Volume: 111 Pages: 3805-3810
  • DOI: 10.1073/pnas.1320265111
  • Peer Reviewed
• [Journal Article] Circulating AIM prevents hepatocellular carcinoma through complement activation (2014)
  • Author(s): Maehara, N., Arai, S., Mori, M., Iwamura, Y., Kurokawa, J., Kai, T., Kusunoki, S., Taniguchi, K., Ikeda, K., Ohara, O., Yamamura, K. and Miyazaki, T.
  • Journal Title: Cell Report Volume: 9 Pages: 1-14
  • DOI: 10.1016/j.celrep.2014.08.058
  • Peer Reviewed
• [Journal Article] Disruption of dystonin protein containing actin-binding domain cause dystonia musculorum in mice (2014)
  • Author(s): Horie, M., Watanabe, K., Bepari, A.K., Nashimoto, J., Araki, K., Sano, H., Chiken, S., Nambu, A., Ono, K., Ikenaka, K., Kakita, A., Yamamura, K. and Takebayashi, H.
  • Journal Title: Eur. J. Neurocsi Volume: 40 Pages: 3458-3471
  • DOI: 10.1111/ejn.12711
  • Peer Reviewed
• [Journal Article] Circulating AIM as an indicator of liver damage and hepatocellular carcinoma in humans (2014)
  • Author(s): Yamazaki, T., Mori, M., Arai, S., Tateishi, R., Abe, M., Ban, M., Nishijima, A., Maeda, M., Asano, T., Kai, T., Izumino, K., Takahashi, J., Aoyama, K., Harada, S., Takebayashi, T., Gunji, T, Ohnishi, S., Seto, S., Yoshida, Y., Hiasa, Y., Koike, K., Yamamura, K., Inoue, K. & Miyazaki, T.
  • Journal Title: Plos One Volume: 9 Pages: e109123
  • DOI: 10.1371/journal.pone.0109123
  • Peer Reviewed
• [Journal Article] Database for exchangeable gene trap clones : Pathway and gene ontology analysis of exchangeable genetrap clone mouse lines (2014)
  • Author(s): Araki, M., Nakahara, M., Muta, M., Itou, M., Yanai, C., Yamazoe, F., Miyake, M., Morita, A., Araki, M., Okamoto, Y., Nakagata, M., Yoshinobu, K., Yamamura, K. and Araki, K.
  • Journal Title: Develop. Growth Differ Volume: 56 Pages: 161-174
  • DOI: 10.1111/dgd.12116
  • Peer Reviewed
• [Journal Article] Screening Methods to Identify TALEN-Mediated Knockout Mice (2014)
  • Author(s): Nakagawa, Y., Yamamoto, T., Suzuki, K., Araki, K., Takeda, N., Ohmuraya, M. and Sakuma, T.
  • Journal Title: Exp. Anim. Volume: 63 Pages: 79-84
  • Peer Reviewed
• [Journal Article] Role of blood ribosomal protein S19 in coagulum resorption : a study using Gln137Glu-ribosomal protein S19 gene knock-in mouse (2014)
  • Author(s): Chen, J., Fujino, R., Zhao, R., Semba, U., Araki, K. and Yamamoto, T.
  • Journal Title: Pathol. Int. Volume: 64 Pages: 543-550
  • DOI: 10.1111/pin.12208
  • Peer Reviewed
• [Journal Article] Conformational Change in Transfer RNA Is an Early Indicator of Acute Cellular Damage (2014)
  • Author(s): Mishima, E., Inoue, C., Saigusa, D., Inoue, R., Ito, K., Suzuki, Y., Jinno, D., Tsukui, Y., Akamatsu, Y., Araki, M., Araki, K., Shimizu, R., Shinke, H., Suzuki, T., Takeuchi, Y., Shima, H., Akiyama, Y., Yamamura, K., et al.
  • Journal Title: J. Am. Soc. Nephrol Volume: 25 Pages: 2316-2326
  • DOI: 10.1681/ASN.2013091001
  • Peer Reviewed
• [Journal Article] Impaired degradation of WNK1 and WNK4 kinases causes PHAII in mutant KLHL3 knock-in mice (2014)
  • Author(s): Susa, K, Sohara, E, Rai, T, Zeniya, M, Mori, Y, Mori, T, Chiga, M, Nomura, N, Nishida, H, Takahashi, D, Isobe, K, Inoue, Y, Takeishi, K, Takeda, N, Sasaki, S, Uchida, S
  • Journal Title: Hum Mol Genet Volume: 23 Pages: 5052-5060
  • DOI: 10.1093/hmg/ddu217
  • Peer Reviewed
• [Journal Article] Novel retinoblastoma mutation abrogating the interaction to E2F2/3, but not E2F1, led to selective suppression of thyroid tumors (2014)
  • Author(s): Toki, H., Inoue, M., Minowa, O., Motegi, H., Saiki, Y., Wakana, S., Masuya, H., Gondo, Y., Shiroishi, T., Yao, R. & Noda, T.
  • Journal Title: Cancer Sci Volume: 105 Pages: 1360-1368
  • DOI: 10.1111/cas.12495
  • Peer Reviewed
• [Journal Article] Deficiency of Transcription Factor Brn4 Disrupts Cochlear Gap Junction Plaques in a Model of DFN3 Non-Syndromic Deafness (2014)
  • Author(s): Kidokoro Y, Karasawa K, Minowa O, Sugitani Y., Noda T, Ikeda K, Kamiya K.
  • Journal Title: PLoS One Volume: 9 Issue: 9 Pages: e108216
  • DOI: 10.1371/journal.pone.0108216
  • Peer Reviewed
• [Journal Article] Assembly of the cochlear gap junction macromolecular complex requires connexin 26 (2014)
  • Author(s): Kamiya K, Yum SW, Kurebayashi N, Muraki M, Ogawa K, Karasawa K, Miwa A, Guo X, Gotoh S, Sugitani Y., Yamanaka H, Ito-Kawashima S, Iizuka T, Sakurai T, Noda T, Minowa O, Ikeda K.
  • Journal Title: J. Clin. Invest. Volume: 124 Issue: 4 Pages: 1598-1607
  • DOI: 10.1172/JCI67621
  • Peer Reviewed
• [Journal Article] Identification of genomic locus responsible for experimentally induced testicular teratoma 1 (ettl) on mouse Chr 18 (2014)
  • Author(s): Miyazaki, T., Ikeda, Y., Kubo, I., Suganuma, S., Fujita, N., Itakura, M., Hayashi, T., Takabayashi, S., Katoh, H., Ohira, Y., Sato, M., Noguchi, M., Tokumoto, T.
  • Journal Title: Mammalian Genome Volume: 25 Pages: 317-326
  • DOI: 10.1007/s00335-014-9529-8
  • Peer Reviewed
• [Journal Article] Contemporary techniques for freezing mouse spermatozoa (2014)
  • Author(s): Guan, M., Bogani D., Marschall, S., Raspa M., Takeo, T., Nakagata, N., Taft, R. and Fray, M.
  • Journal Title: Curr Protoc Mouse Biol Volume: 4 Issue: 3 Pages: 85-104
  • DOI: 10.1002/9780470942390.mo140065
  • Peer Reviewed
• [Journal Article] In vitro fertilization in mice using the MBCD-GSH protocol (2014)
  • Author(s): Guan, M., Bogani, D., Marschall, S., Raspa, M., Takeo, T., Nakagata, N. and Fray, M.
  • Journal Title: Curr Protoc Mouse Biol Volume: 4 Issue: 2 Pages: 67-83
  • DOI: 10.1002/9780470942390.mo140059
  • Peer Reviewed
• [Journal Article] Transporting mouse embryos and germplasm as frozen or unfrozen materials (2014)
  • Author(s): Kenyon, J., Guan, M., Bogani, D., Marschall, S., Raspa, M., Pickard, A., Takeo, T., Nakagata, N. and Fray, M.
  • Journal Title: Curr Protoc Mouse Biol Volume: 4 Issue: 2 Pages: 47-65
  • DOI: 10.1002/9780470942390.mo140064
  • Peer Reviewed
• [Journal Article] Conservation of mouse models through embryo freezing (2014)
  • Author(s): Guan, M, Bogani, D, Marschall, S, Raspa, M, Takeo, T, Nakagata, N, Fray, M
  • Journal Title: Curr Protoc Mouse Biol Volume: 4 Issue: 4 Pages: 205-227
  • DOI: 10.1002/9780470942390.mo140082
  • Peer Reviewed
• [Journal Article] Rescue in vitro fertilization method for legacy stock of frozen mouse sperm (2014)
  • Author(s): Nakagata, N, Takeo, T, Fukumoto, K, Haruguchi, Y, Kondo, T, Takeshita, Y, Nakamuta, Y, Umeno, T, Tsuchiyama, S
  • Journal Title: J Reprod Dev Volume: 60 Issue: 2 Pages: 168-171
  • Peer Reviewed
• [Journal Article] Application of oocyte cryopreservation technology in TALEN-mediated mouse genome editing (2014)
  • Author(s): Nakagawa, Y., Sakuma, T., Nakagata, N., Yamasaki, S., Takeda, N., Ohmuraya, M. and Yamamoto, T.
  • Journal Title: Exp Anim Volume: 63 Issue: 3 Pages: 349-355
  • Peer Reviewed
• [Journal Article] Histological detection of catalytic ferrous iron with the selective turn-on fluorescent probe RhoNox-1 in a Fenton reaction-based rat renal carcinogenesis model (2014)
  • Author(s): Mukaide, T, Hatori, Y, Misawa, N, Funahashi, S, Jiang, L, Hirayama, T, Nagasawa, H and Toyokuni, S
  • Journal Title: Free Radic Res Volume: 48 Pages: 990-995
  • DOI: 10.3109/10715762.2014.898844
  • Peer Reviewed
• [Journal Article] Connective tissue growth factor and β-catenin constitute an autocrine loop for activation in rat sarcomatoid mesothelioma (2014)
  • Author(s): Jiang, L, Yamashita, Y, Chew, SH, AKatsuka, S, Ukai, S, Wang, S, Nagai, H, Okazaki, Y, Takahashi, T and Toyokuni, S
  • Journal Title: J Pathol Volume: 233 Pages: 402-414
  • DOI: 10.1002/path.4377
  • Peer Reviewed
• [Journal Article] Iron and thiols as two major players in carcinogenesis : friends or foes? (2014)
  • Author(s): Toyokuni, S.
  • Journal Title: Front Pharmacol Volume: 5 Pages: 200
  • DOI: 10.3389/fphar.2014.00200
  • Peer Reviewed
• [Journal Article] Hsc70 contributes to cancer cell survival by preventing RablA degradation under stress conditions (2014)
  • Author(s): Tanaka, M, Mun, S, Harada, A, Ohkawa, Y, Inagaki, A, Sano, S, Takahashi, K, Izumi, Y, Osada-Oka, M, Wanibuchi, H, Yamagata, M, Yukimura, T, Miura, K, Shiota, M, Iwao, H
  • Journal Title: PLoS One Volume: 9 Pages: e96785
  • DOI: 10.1371/journal.pone.0096785
  • Peer Reviewed
• [Journal Article] Inhibitory effect of raphanobrassica on Helicobacter pylori-induced gastritis in Mongolian gerbils (2014)
  • Author(s): Yamada, T, Wei, M, Toyoda, T, Yamano, S, Wanibuchi, H
  • Journal Title: Food Chem Toxicol Volume: 70 Pages: 107-113
  • DOI: 10.1016/j.fct.2014.04.037
  • Peer Reviewed
• [Journal Article] Genotoxicity and subacute toxicity studies of a new astaxanthin-containing Phaffia rhodozyma extract (2014)
  • Author(s): Tago, Y, Fujii, T, Wada, J, Kato, M, Wei, M, Wanibuchi, H, Kitano, M
  • Journal Title: J Toxicol Sci Volume: 39 Pages: 373-382
  • Peer Reviewed
• [Journal Article] Vascular endothelial growth factor mRNA levels as a biomarker for short-term N-butyl-N-(4-hydroxybutyl) nitrosamine-induced rat bladder carcinogenesis bioassay (2014)
  • Author(s): Wakui, S, Mutou, T, Takahashi, H, Ikegami, M, Wanibuchi, H, Fukushima, S
  • Journal Title: J Appl Toxicol Volume: 35 Issue: 2 Pages: 181-190
  • DOI: 10.1002/jat.3021
  • Peer Reviewed
• [Journal Article] Valerian inhibits rat hepatocarcinogenesis by activating GABA(A) receptor-mediated signaling (2014)
  • Author(s): Kakehashi, A, Kato, A, Ishii, N, Wei, M, Morimura, K, Fukushima, S, Wanibuchi, H
  • Journal Title: PLoS One Volume: 9 Pages: e113610
  • DOI: 10.1371/journal.pone.0113610
  • Peer Reviewed
• [Journal Article] Establishment of neutralizing rat monoclonal antibodies for fibroblast growth factor-2 (2014)
  • Author(s): Tanaka, M, Yamaguchi, M, Shiota, M, Kawamoto, Y, Takahashi, K, Inagaki, A, Osada-Oka, M, Harada, A., Wanibuchi, H, Izumi, Y, Miura, K, Iwao, H, Ohkawa, Y
  • Journal Title: Monoclon Antib Immunodiagn Immunother Volume: 33 Pages: 261-269
  • DOI: 10.1089/mab.2013.0085
  • Peer Reviewed
• [Journal Article] Comparative proteomics analysis of gastric cancer stem cells (2014)
  • Author(s): Morisaki, T, Yashiro, M, Kakehashi, A, Inagaki, A, Kinoshita, H, Fukuoka, T, Kasashima, H, Masuda, G, Sakurai, K, Kubo, N, Muguruma, K, Ohira, M., Wanibuchi, H, Hirakawa, K
  • Journal Title: PLoS One Volume: 9 Pages: e110736
  • DOI: 10.1371/journal.pone.0110736
  • Peer Reviewed
• [Journal Article] Nanosized zinc oxide particles do not promote DHPN-induced lung carcinogenesis but cause reversible epithelial hyperplasia of terminal bronchioles (2014)
  • Author(s): Xu, J., Futakuchi, M., Alexander, D.B., Fukamachi, K., Numano, T., Suzui, M., Shimizu, H., Omori, T., Kanno, J., Hirose, A., and Tsuda, H
  • Journal Title: Archives of toxicology Volume: 88 Pages: 65-75
  • DOI: 10.1007/s00204-013-1086-5
  • Peer Reviewed
• [Journal Article] Size-and shape-dependent pleural translocation, deposition, fibrogenesis, and mesothelial proliferation by multiwalled carbon nanotubes (2014)
  • Author(s): Xu, J., Alexander, D.B., Futakuchi, M., Numano, T., Fukamachi, K., Suzui, M., Omori, T., Kanno, J., Hirose, A., and Tsuda, H
  • Journal Title: Cancer Sci Volume: 105 Pages: 763-769
  • DOI: 10.1111/cas.12437
  • Peer Reviewed
• [Journal Article] Comparative study of toxic effects of anatase and rutile type nanosized titanium dioxide particles in vivo and in vitro (2014)
  • Author(s): Numano, T., Xu, J., Futakuchi, M., Fukamachi, K., Alexander, D.B., Furukawa, F., Kanno, J., Hirose, A., Tsuda, H., and Suzui, M
  • Journal Title: Asian Pacific J Cancer Prev Volume: 15 Pages: 929-935
  • Peer Reviewed
• [Journal Article] Rat N-ERC/mesothelin as a marker for in vivo screening of drugs against pancreas cancer (2014)
  • Author(s): Fukamachi, K., Iigo, M., Hagiwara, Y., Shibata, K., Futakuchi, M., Alexander, D.B., Hino, O., Suzui, M., and Tsuda, H
  • Journal Title: Plos One Volume: 9 Pages: e111481
  • DOI: 10.1371/journal.pone.0111481
  • Peer Reviewed
• [Journal Article] Murine Herc6 plays a critical role in protein ISGylation in vivo and has an ISGylation independent function in seminal vesicles (2014)
  • Author(s): Arimoto, K.-i., Hishiki, T., Kiyonari, H., Abe, T., Cheng, C., Yan, M., Fan, J.-B., Futakuchi, M., Tsuda, H., Murakami, Y., Suzuki, H., Zhang, D.-E., and Shimotohno, K.
  • Journal Title: J. Interferon & Cytokine Res
  • DOI: 10.1089/jir.2014.0113
  • Peer Reviewed
• [Journal Article] Significance of the progesterone receptor and epidermal growth factor receptor, but not the estrogen receptor, in chemically induced lung carcinogenesis in female A/J mice (2014)
  • Author(s): Kishi S, Yokohira M, Yamakawa K, Saoo K, Imaida K
  • Journal Title: Oncol. Lett Volume: 8 Pages: 2379-2386
  • Peer Reviewed
• [Journal Article] Napsin A is possibly useful marker to predict the tumorigenic potential of lung bronchiolo-alveolar hyperplasia in F344 rats (2014)
  • Author(s): Yokohira M, Kishi S, Yamakawa K, Nakano Y, Ninomiya F, Kinouch s, Tanizawa J, Saoo K, Imaida K
  • Journal Title: Exp. Toxicol. Pathol Volume: 66 Pages: 117-123
  • DOI: 10.1016/j.etp.2013.11.002
  • Peer Reviewed
• [Journal Article] The peroxisome proliferator-activated receptor(PPAR)a agonist fenofibrate suppresses chemically induced lung alveolar proliferative lesions in male obese hyperlipidemic mice (2014)
  • Author(s): Kuno T, Hata K, Takamatsu M, Hara A, Hirose Y, Takahashi S, Imaida K, Tanaka T
  • Journal Title: Int. J. Mol. Sci Volume: 15 Pages: 9160-9172
  • DOI: 10.3390/ijms15059160
  • Peer Reviewed
• [Journal Article] Immunohistochemical characteristics of surfactant proteins-A, -B, -C and -D in inflammatory and tumorigenic lung lesions of F344 rats (2014)
  • Author(s): Yokohira M, Yamakawa K, Nakano Y, Numano T, Furukawa F, Kishi S, Ninomiya F, Kanie S, Hitotsumachi H, Saoo K, Imaida K
  • Journal Title: J. Toxicol. Pathol Volume: 27 Pages: 175-182
  • DOI: 10.1293/tox.2014-0020
  • Peer Reviewed
• [Journal Article] Rat strain differences in levels and effects of chronic inflammation due to intratracheal instillation of quartz on lung tumorigenesis induced by DHPN (2014)
  • Author(s): Nakano Y, Yokohira M, Hashimoto N, Yamakawa K, Kishi S, Ninomiya F, Kanie S, Saoo K, Imaida K
  • Journal Title: Exp. Toxicol. Pathol Volume: 66 Pages: 391-401
  • DOI: 10.1016/j.etp.2014.06.002
  • Peer Reviewed
• [Journal Article] Hepatoid giant cell tumor of tendon sheath-A rare morphologic variant case report (2014)
  • Author(s): Yoshimoto, T., Motoi, N., Kanda, H., Tanizawa, T., Shimoji, T., Matsumoto, S., Mukai, H., Ishikawa, Y., Machinami, R.
  • Journal Title: Pathology Res. Practice Volume: 14 Pages: 167-168
  • DOI: 10.1016/j.prp.2014.05.012
  • Peer Reviewed
• [Journal Article] FFT法と領域法を組み合わせたDNA ploidy解析によるがん診断法の研究 (2014)
  • Author(s): 日向奈恵、神田浩明、塩山高広、鈴木あかね、武田朴、石川雄一、山口俊晴、加藤洋
  • Journal Title: 生体医工学 Volume: 52 Pages: 136-144
  • DOI: 10.11239/jsmbe.52.136
  • Peer Reviewed
• [Journal Article] Premature termination of reprogramming in vivo leads to cancer development through altered epigenetic regulation (2014)
  • Author(s): Ohnishi K., Semi K., Yamamoto T., Shimizu M., Tanaka A., Mitsunaga K., Okita K., Osafune K., Arioka Y., Maeda T., Soejima H., Moriwaki H., Yamanaka S., Woltjen K., Yamada Y.
  • Journal Title: Cell Volume: 156 Pages: 663-77
  • DOI: 10.1016/j.cell.2014.01.005
  • Peer Reviewed
• [Journal Article] A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer (2014)
  • Author(s): Al Olama, A.A., Kote-Jarai Z., Bemdt S.I., Conti D.V., Schumacher F., Han Y., Benlloch S., Hazelett D.J., Wang Z., Saunders E., Leongamornlert D., Lindstrom S., Jugurnauth-Little S., Dadaev T., Tymrakiewicz M., Stram D.O., Rand K., Wan P., Stram A., Kubo M., et al.
  • Journal Title: Nat Genet Volume: 46 Pages: 1103-1109
  • DOI: 10.1038/ng.3094
  • Peer Reviewed
• [Journal Article] Infection with Porphyromonas gingivalis exacerbates endothelial injury in obese mice (2014)
  • Author(s): Ao, M., Miyauchi M., Inubushi T., Kitagawa M., Furusho H., Ando T., Ayuningtyas N.F., Nagasaki A., Ishihara K., Tahara H., Kozai K. and Takata T.
  • Journal Title: PLoS One Volume: 9 Pages: e110519
  • DOI: 10.1371/journal.pone.0110519
  • Peer Reviewed
• [Journal Article] Development of a SNP set for human identification : A set with high powers of discrimination which yields high genetic information from naturally degraded DNA samples in the Thai population (2014)
  • Author(s): Boonyarit, H., Mahasirimongkol S., Chavalvechakul N., Aoki M., Amitani H., Hosono N., Kamatani N., Kubo M. and Lertrit P.
  • Journal Title: Forensic Sci Int Genet Volume: 11 Pages: 166-173
  • DOI: 10.1016/j.fsigen.2014.03.010
  • Peer Reviewed
• [Journal Article] Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1,5q14.3 and 15q26.1 (2014)
  • Author(s): Cai, Q., Zhang B., Sung H., Low S.K., Kweon S.S., Shen C.Y., Matsuo K., Teo S.H., Kim M.K., Iwasaki M., Hartman M., Takahashi A., Ashikawa K., Matsuda K., Ito H., Kasuga Y., Iwata H., Tsugane S., Nakamura Y., Kubo M., et al.
  • Journal Title: Nat Genet Volume: 46 Pages: 886-890
  • DOI: 10.1038/ng.3041
  • Peer Reviewed
• [Journal Article] Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians (2014)
  • Author(s): Chen, P., Takeuchi F., Lee J.Y., Li H., Wu J.Y., Tabara Y., Goodarzi M.O., Pereira M.A., Kim Y.J., Go M.J., Stram D.O., Vithana E., Isono M., Yamamoto K., Ohnaka K., Takayanagi R., Kita Y., Ueshima H., Okada Y., Kubo M., et al.
  • Journal Title: Diabetes Volume: 63 Pages: 2551-2562
  • DOI: 10.2337/db13-1815
  • Peer Reviewed
• [Journal Article] Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101(Alliance) (2014)
  • Author(s): Chhibber, A., Mefford J., Stahl E.A., Pendergrass S.A., Baldwin R.M., Owzar K., Li M., Winer E.P., Hudis C.A., Zembutsu H., Kubo M., Nakamura Y., McLeod H.L., Ratain M.J., Shulman L.N., Ritchie M.D., Plenge R.M., Witte J.S. and Kroetz D.L.
  • Journal Title: Pharmacogenomics J Volume: 14 Pages: 336-342
  • DOI: 10.1038/tpj.2014.2
  • Peer Reviewed
• [Journal Article] Establishment of CYP2D6 reference samples by multiple validated genotyping platforms (2014)
  • Author(s): Fang, H., Liu X., Ramirez J., Choudhury N., Kubo M., Im H.K., Konkashbaev A., Cox N.J., Ratain M.J., Nakamura Y. and O'Donnell P.H.
  • Journal Title: Pharmacogenomics J Volume: 14 Pages: 564-572
  • DOI: 10.1038/tpj.2014.27
  • Peer Reviewed
• [Journal Article] Genetic variants in transcription factors are associated with the pharmacokinetics and pharmacodynamics of metformin (2014)
  • Author(s): Goswami, S., Yee S.W., Stocker S., Mosley J.D., Kubo M., Castro R., Mefford J.A., Wen C., Liang X., Witte J., Brett C., Maeda S., Simpson M.D., Hedderson M.M., Davis R.L., Roden D.M., Giacomini K.M. and Savic R.M.
  • Journal Title: Clin Pharmacol Ther Volume: 96 Pages: 370-379
  • DOI: 10.1038/clpt.2014.109
  • Peer Reviewed
• [Journal Article] A novel RET rearrangement (ACBD5/RET) by pericentric inversion, inv(10)(p12.1 ; q11.2), in papillary thyroid cancer from an atomic bomb survivor exposed to high-dose radiation (2014)
  • Author(s): Hamatani, K., Eguchi H., Koyama K., Mukai M., Nakachi K. and Kusunoki Y.
  • Journal Title: Oncol Rep Volume: 32 Pages: 1809-1814
  • DOI: 10.3892/or.2014.3449
  • Peer Reviewed
• [Journal Article] Associations between hOGG1 Ser326Cys polymorphism and increased body mass index and fasting glucose level in the Japanese general population (2014)
  • Author(s): Hara, M., Nakamura K., Nanri H., Nishida Y., Hishida A., Kawai S., Hamajima N., Kita Y., Suzuki S., Mantjoro E.M., Ohnaka K., Uemura H., Matsui D., Oze I., Mikami H., Kubo M., Tanaka H. and Japan Multi-Institutional Collaborative Cohort Study Group
  • Journal Title: J Epidemiol Volume: 24 Pages: 379-384
  • Peer Reviewed
• [Journal Article] Cancer Philosophy～Thinking“Cancer Cells”Deeply (2014)
  • Author(s): Hino, O
  • Journal Title: Juntendo Medical Journal Volume: 60 Pages: 200-209
  • Peer Reviewed
• [Journal Article] Telomeric g-tail length and hospitalization for cardiovascular events in hemodialysis patients (2014)
  • Author(s): Hirashio, S., Nakashima A., Doi S., Anno K., Aoki E., Shimamoto A., Yorioka N., Kohno N., Masaki T. and Tahara H
  • Journal Title: Clin J Am Soc Nephrol Volume: 9 Pages: 2117-2122
  • DOI: 10.2215/CJN.10010913
  • Peer Reviewed
• [Journal Article] Retrospective analysis of large-scale research screening of construction workers for the early diagnosis of mesothelioma (2014)
  • Author(s): Hirohashi, T., Igarashi K., Abe M., Maeda M. and Hino O.
  • Journal Title: Mol Clin Oncol Volume: 2 Pages: 26-30
  • DOI: 10.3892/mco.2013.197
  • Peer Reviewed
• [Journal Article] CBP-93872 inhibits NBS1-mediated ATR activation, abrogating maintenance of the DNA double-strand break-specific G2 checkpoint (2014)
  • Author(s): Hirokawa, T., Shiotani B., Shimada M., Murata K., Johmura Y., Haruta M., Tahara H., Takeyama H. and Nakanishi M.
  • Journal Title: Cancer Res Volume: 74 Pages: 3880-3889
  • DOI: 10.1158/0008-5472.CAN-13-3604
  • Peer Reviewed
• [Journal Article] GCK, GCKR polymorphisms and risk of chronic kidney disease in Japanese individuals : data from the J-MICC Study (2014)
  • Author(s): Hishida, A., Takashima N., Turin T.C., Kawai S., Wakai K., Hamajima N., Hosono S., Nishida Y., Suzuki S., Nakahata N., Mikami H., Ohnaka K., Matsui D., Katsuura-Kamano S., Kubo M., Tanaka H. and Kita Y.
  • Journal Title: J Nephrol Volume: 27 Pages: 143-149
  • DOI: 10.1007/s40620-013-0025-0
  • Peer Reviewed
• [Journal Article] Polymorphisms of genes involved in lipid metabolism and risk of chronic kidney disease in Japanese-cross-sectional data from the J-MICC study (2014)
  • Author(s): Hishida, A., Wakai K., Naito M., Suma S., Sasakabe T., Hamajima N., Hosono S., Horita M., Turin T.C., Suzuki S., Kairupan T.S., Mikami H., Ohnaka K., Watanabe I., Uemura H., Kubo M., Tanaka H, and J-Micc Study Group
  • Journal Title: Lipids Health Dis Volume: 13 Pages: 162
  • DOI: 10.1186/1476-511X-13-162
  • Peer Reviewed
• [Journal Article] TERT attenuated ER stress-induced cell death (2014)
  • Author(s): Hosoi, T., Inoue Y., Nakatsu K., Matsushima N., Kiyose N., Shimamoto A., Tahara H. and Ozawa K.
  • Journal Title: Biochem Biophys Res Commun Volume: 447 Pages: 378-382
  • DOI: 10.1016/j.bbrc.2014.04.034
  • Peer Reviewed
• [Journal Article] Circulating tumor cell count during zoledronic acid treatment in men with metastatic prostate cancer : a pilot study (2014)
  • Author(s): Ide, H., Lu Y., Tanaka T., Wakumoto Y., Kitamura K., Muto S., Yamaguchi R., Masumori N. and Horie S.
  • Journal Title: Prostate Int Volume: 2 Pages: 147-151
  • DOI: 10.12954/PI.14056
  • Peer Reviewed
• [Journal Article] Asbestos-related mesothelioma : Prevention, early detection, treatment (2014)
  • Author(s): Imai, M. and Hino O.
  • Journal Title: JSM Clinical Oncology and Research Volume: 2 Issue: 3 Pages: 1018
  • Peer Reviewed
• [Journal Article] ERC/mesothelin is expressed in human gastric cancer tissues and cell lines (2014)
  • Author(s): Ito, T., Kajino K., Abe M., Sato K., Maekawa H., Sakurada M., Orita H., Wada R., Kajiyama Y. and Hino O.
  • Journal Title: Oncol Rep Volume: 31 Pages: 27-33
  • DOI: 10.3892/or.2013.2803
  • Peer Reviewed
• [Journal Article] Association of EPAS1 gene rs4953354 polymorphism with susceptibility to lung adenocarcinoma in female Japanese non-smokers (2014)
  • Author(s): Iwamoto, S., Tanimoto K., Nishio Y., Putra A.C., Fuchita H., Ohe M., Sutani A., Kuraki T., Hiyama K., Murakami I., Eguchi H. and Isobe T.
  • Journal Title: J Thorac Oncol Volume: 9 Pages: 1709-1713
  • DOI: 10.1097/JTO.0000000000000309
  • Peer Reviewed
• [Journal Article] Citalopram and escitalopram plasma drug and metabolite concentrations : genome-wide associations (2014)
  • Author(s): Ji, Y., Schaid D.J., Desta Z., Kubo M., Batzler A.J., Snyder K., Mushiroda T., Kamatani N., Ogburn E., Hall-Flavin D., Flockhart D., Nakamura Y., Mrazek D.A. and Weinshilboum R.M.
  • Journal Title: Br J Clin Pharmacol Volume: 78 Pages: 373-383
  • DOI: 10.1111/bcp.12348
  • Peer Reviewed
• [Journal Article] EP2 signaling mediates suppressive effects of celecoxib on androgen receptor expression and cell proliferation in prostate cancer (2014)
  • Author(s): Kashiwagi, E., Shiota M., Yokomizo A., Inokuchi J., Uchiumi T. and Naito S.
  • Journal Title: Prostate Cancer Prostatic Dis Volume: 17 Pages: 10-17
  • DOI: 10.1038/pcan.2013.53
  • Peer Reviewed
• [Journal Article] A polymorphism near MC4R gene (rs17782313) is associated with serum triglyceride levels in the general Japanese population : the J-MICC Study (2014)
  • Author(s): Katsuura-Kamano, S., Uemura H., Arisawa K., Yamaguchi M., Hamajima N., Wakai K., Okada R., Suzuki S., Taguchi N., Kita Y., Ohnaka K., Kairupan T.S., Matsui D., Oze I., Mikami H., Kubo M. and Tanaka H.
  • Journal Title: Endocrine Volume: 47 Pages: 81-89
  • DOI: 10.1007/s12020-014-0306-y
  • Peer Reviewed
• [Journal Article] Trans-ethnic meta-analysis of white blood cell phenotypes (2014)
  • Author(s): Keller, M.F., Reiner A.P., Okada Y., van Rooij F.J., Johnson A.D., Chen M.H., Smith A.V., Morris A.P., Tanaka T., Ferrucci L., Zonderman A.B., Lettre G., Kamatani Y., Matsuda K., Kamatani N., Nakamura Y., Kubo M., Takahashi A., Wilson J.G., BioBank Japan Project Working Groups, et al.
  • Journal Title: Hum Mol Genet Volume: 23 Pages: 6944-6960
  • DOI: 10.1093/hmg/ddu401
  • Peer Reviewed
• [Journal Article] SOD3 acts as a tumor suppressor in PC-3 prostate cancer cells via hydrogen peroxide accumulation (2014)
  • Author(s): Kim, J., Mizokami A., Shin M., Izumi K., Konaka H., Kadono Y., Kitagawa Y., Keller E.T., Zhang J. and Namiki M.
  • Journal Title: Anticancer Res Volume: 34 Pages: 2821-2831
  • Peer Reviewed
• [Journal Article] A genome-wide association study to identify genomic modulators of rate control therapy in patients with atrial fibrillation (2014)
  • Author(s): Kolek, M.J., Edwards T.L., Muhammad R., Balouch A., Shoemaker M.B., Blair M.A., Kor K.C., Takahashi A., Kubo M., Roden D.M., Tanaka T. and Darbar D.
  • Journal Title: Am J Cardiol Volume: 114 Pages: 593-600
  • DOI: 10.1016/j.amjcard.2014.05.040
  • Peer Reviewed
• [Journal Article] Combination of bevacizumab and acyclic retinoid inhibits the growth of hepatocellular carcinoma xenografts (2014)
  • Author(s): Kubota, M., Shimizu M., Baba A., Ohno T., Kochi T., Shirakami Y. and Moriwaki H.
  • Journal Title: J Nutr Sci Vitaminol (Tokyo) Volume: 60 Pages: 357-362
  • DOI: 10.3177/jnsv.60.357
  • Peer Reviewed
• [Journal Article] Aromatase inhibitor-associated bone fractures : a case-cohort GWAS and functional genomics (2014)
  • Author(s): Liu, M., Goss P.E., Ingle J.N., Kubo M., Furukawa Y., Batzler A., Jenkins G.D., Carlson E.E., Nakamura Y., Schaid D.J., Chapman J.A., Shepherd L.E., Ellis M.J., Khosla S., Wang L. and Weinshilboum R.M.
  • Journal Title: Mol Endocrinol Volume: 28 Pages: 1740-1751
  • DOI: 10.1210/me.2014-1147
  • Peer Reviewed
• [Journal Article] Minimal experimental requirements for definition of extracellular vesicles and their functions : a position statement from the International Society for Extracellular Vesicles (2014)
  • Author(s): Lotvall, J., Hill A.F., Hochberg F., Buzas E.I., Di Vizio D., Gardiner C., Gho Y.S., Kurochkin I.V., Mathivanan S., Quesenberry P., Sahoo S., Tahara H., Wauben M.H., Witwer K.W. and Thery C.
  • Journal Title: J Extracell Vesicles Volume: 3 Pages: 26913
  • DOI: 10.3402/jev.v3.26913
  • Peer Reviewed
• [Journal Article] Genome-wide association study : a useful tool to identify common genetic variants associated with drugtoxicity and efficacy in cancer pharmacogenomics (2014)
  • Author(s): Low, S.K., Takahashi A., Mushiroda T. and Kubo M.
  • Journal Title: Clin Cancer Res Volume: 20 Pages: 2541-2552
  • DOI: 10.1158/1078-0432.CCR-13-2755
  • Peer Reviewed
• [Journal Article] Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese (2014)
  • Author(s): Lubitz, S.A., Lunetta K.L., Lin H., Arking D.E., Trompet S., Li G., Krijthe B.P., Chasman D.I., Barnard J., Kleber M.E., Dorr M., Ozaki K., Smith A.V., Muller-Nurasyid M., Walter S., Agarwal S.K., Kubo M., Tanaka T., Heckbert S.R., Jukema J.W., et al.
  • Journal Title: J Am Coll Cardiol Volume: 63 Pages: 1200-1210
  • DOI: 10.1016/j.jacc.2013.12.015
  • Peer Reviewed
• [Journal Article] Ethical challenges for the design and conduct of mega-biobanking from Great East Japan Earthquake victims (2014)
  • Author(s): Matsui, K. and Tashiro S.
  • Journal Title: BMC Med Ethics Volume: 15 Pages: 55
  • DOI: 10.1186/1472-6939-15-55
  • Peer Reviewed
• [Journal Article] DSE-FRET : A new anticancer drug screening assay for DNA binding proteins (2014)
  • Author(s): Miyagi, T., Shiotani B., Miyoshi R., Yamamoto T., Oka T., Umezawa K., Ochiya T., Takano M. and Tahara H.
  • Journal Title: Cancer Sci Volume: 105 Pages: 870-874
  • DOI: 10.1111/cas.12420
  • Peer Reviewed
• [Journal Article] Proposed salvage treatment strategy for biochemical failure after radical prostatectomy in patients with prostate cancer : a retrospective study (2014)
  • Author(s): Miyake, M., Tanaka N., Asakawa I., Morizawa Y., Anai S., Torimoto K., Aoki K., Yoneda T., Hasegawa M., Konishi N. and Fujimoto K.
  • Journal Title: Radiat Oncol Volume: 9 Pages: 208
  • DOI: 10.1186/1748-717X-9-208
  • Peer Reviewed
• [Journal Article] Photodynamic diagnosis of shed prostate cancer cells in voided urine treated with 5-aminolevulinic acid (2014)
  • Author(s): Nakai, Y., Anai S., Kuwada M., Miyake M., Chihara Y., Tanaka N., Hirayama A., Yoshida K., Hirao Y. and Fujimoto K.
  • Journal Title: BMC Urol Volume: 14 Pages: 59
  • DOI: 10.1186/1471-2490-14-59
  • Peer Reviewed
• [Journal Article] A genome-wide association study identifies susceptibility loci for ossification of the posterior longitudinal ligament of the spine (2014)
  • Author(s): Nakajima, M., Takahashi A., Tsuji T., Karasugi T., Baba H., Uchida K., Kawabata S., Okawa A., Shindo S., Takeuchi K., Taniguchi Y., Maeda S., Kashii M., Seichi A., Nakajima H., Kawaguchi Y., Fujibayashi S., Takahata M., Tanaka T., Kubo M., et al.
  • Journal Title: Nat Genet Volume: 46 Pages: 1012-1016
  • DOI: 10.1038/ng.3045
  • Peer Reviewed
• [Journal Article] Common dysfunctional variants of ABCG2 have stronger impact on hyperuricemia progression than typical environmental risk factors (2014)
  • Author(s): Nakayama, A., Matsuo H., Nakaoka H., Nakamura T., Nakashima H., Takada Y., Oikawa Y., Takada T., Sakiyama M., Shimizu S., Kawamura Y., Chiba T., Abe J., Wakai K., Kawai S., Okada R., Tamura T., Shichijo Y., Akashi A., Suzuki H., et al.
  • Journal Title: Sci Rep Volume: 4 Pages: 5227
  • DOI: 10.1038/srep05227
  • Peer Reviewed
• [Journal Article] Objectively measured physical activity and inflammatory cytokine levels in middle-aged Japanese people (2014)
  • Author(s): Nishida, Y., Higaki Y., Taguchi N., Hara M., Nakamura K., Nanri H., Imaizumi T., Sakamoto T., Horita M., Shinchi K. and Tanaka K.
  • Journal Title: Prev Med Volume: 64 Pages: 81-87
  • DOI: 10.1016/j.ypmed.2014.04.004
  • Peer Reviewed
• [Journal Article] Association between KCNJ6 (GIRK2) gene polymorphism rs2835859 and post-operative analgesia, pain sensitivity, and nicotine dependence (2014)
  • Author(s): Nishizawa, D., Fukuda K., Kasai S., Ogai Y., Hasegawa J., Sato N., Yamada H., Tanioka F., Sugimura H., Hayashida M. and Ikeda K.
  • Journal Title: J Pharmacol Sci Volume: 126 Pages: 253-263
  • Peer Reviewed
• [Journal Article] Pyrrole-imidazole polyamide targeted to break fusion sites in TMPRSS2 and ERG gene fusion represses prostate tumor growth (2014)
  • Author(s): Obinata, D., Ito A., Fujiwara K., Takayama K., Ashikari D., Murata Y., Yamaguchi K., Urano T., Fujimura T., Fukuda N., Soma M., Watanabe T., Nagase H., Inoue S. and Takahashi S.
  • Journal Title: Cancer Sci Volume: 105 Pages: 1272-1278
  • DOI: 10.1111/cas.12493
  • Peer Reviewed
• [Journal Article] IFNL4/IL-28B haplotype structure and its impact on susceptibility to hepatitis C virus and treatment response in the Japanese population (2014)
  • Author(s): Ochi, H., Miki D., Hayes C.N., Abe H., Hayashida Y., Kubo M. and Chayama K.
  • Journal Title: J Gen Virol Volume: 95 Pages: 1297-1306
  • DOI: 10.1099/vir.0.060103-0
  • Peer Reviewed
• [Journal Article] Genetics of rheumatoid arthritis contributes to biology and drug discovery (2014)
  • Author(s): Okada, Y., Wu D., Trynka G., Raj T., Terao C., Ikari K., Kochi Y., Ohmura K., Suzuki A., Yoshida S., Graham R.R., Bhangale T., Denny J.C., Carroll R.J., Eyler A.E., Kawaguchi T., Kamatani Y., Taniguchi A., Yamada R., Kubo M., et al.
  • Journal Title: Nature Volume: 506 Pages: 376-381
  • DOI: 10.1038/nature12873
  • Peer Reviewed
• [Journal Article] Survey of survival among patients with hepatitis C virus-related hepatocellular carcinoma treated with peretinoin, an acyclic retinoid, after the completion of a randomized, placebo-controlled trial (2014)
  • Author(s): Okita, K., Izumi N., Ikeda K., Osaki Y., Numata K., Ikeda M., Kokudo N., Imanaka K., Nishiguchi S., Kondo S., Nishigaki Y., Shiomi S., Ueshima K., Isoda N., Karino Y., Kudo M., Tanaka K., Kaneko S., Moriwaki H., Makuuchi M., et al.
  • Journal Title: J Gastroenterol
  • DOI: 10.1007/s00535-014-0996-1
  • Description: Epub ahead of print
  • Peer Reviewed
• [Journal Article] Coffee and green tea consumption is associated with upper aerodigestive tractcancer in Japan (2014)
  • Author(s): Oze, I., Matsuo K., Kawakita D., Hosono S., Ito H., Watanabe M., Hatooka S., Hasegawa Y., Shinoda M., Tajima K. and Tanaka H.
  • Journal Title: Int J Cancer Volume: 135 Issue: 2 Pages: 391-400
  • DOI: 10.1002/ijc.28653
  • Peer Reviewed
• [Journal Article] Higher levels of antibodies to the tumour-associated antigen cyclin B1 in cancer-free individuals than in patients with breast cancer (2014)
  • Author(s): Pandey, J.P., Kistner-Griffin E., Namboodiri A.M., Iwasaki M., Kasuga Y., Hamada G.S. and Tsugane S.
  • Journal Title: Clin Exp Immunol Volume: 178 Pages: 75-78
  • DOI: 10.1111/cei.12385
  • Peer Reviewed
• [Journal Article] Genetic predictors associated with improvement of asthma symptoms in response to inhaled corticosteroids (2014)
  • Author(s): Park, H.W., Dahlin A., Tse S., Duan Q.L., Schuemann B., Martinez F.D., Peters S.P., Szefler S.J., Lima J.J., Kubo M., Tamari M. and Tantisira K.G.
  • Journal Title: J Allergy Clin Immunol Volume: 133 Pages: 664-669
  • DOI: 10.1016/j.jaci.2013.12.1042
  • Peer Reviewed
• [Journal Article] Acute case-fatality rates of stroke and acute myocardial infarction in a Japanese population : Takashima stroke and AMI registry, 1989-2005 (2014)
  • Author(s): Rumana, N., Kita Y., Turin T.C., Nakamura Y., Takashima N., Ichikawa M., Sugihara H., Morita Y., Hirose K., Kawakami K., Okayama A., Miura K. and Ueshima H.
  • Journal Title: Int J Stroke Volume: 9 Suppl A100 Pages: 69-75
  • DOI: 10.1111/ijs.12288
  • Peer Reviewed
• [Journal Article] A common variant of organic anion transporter 4(OAT4/SLC22A11) gene is associated with renal underexcretion type gout (2014)
  • Author(s): Sakiyama, M., Matsuo H., Shimizu S., Nakashima H., Nakayama A., Chiba T., Naito M., Takada T., Suzuki H., Hamajima N., Ichida K., Shimizu T. and Shinomiya N.
  • Journal Title: Drug Metab Pharmacokinet Volume: 29 Pages: 208-210
  • Peer Reviewed
• [Journal Article] Ethnic Differences in ATP-binding Cassette Transporter, Sub-family G, Member2 (ABCG2/BCRP) : Genotype Combinations and Estimated Functions (2014)
  • Author(s): Sakiyama, M., Matsuo H., Takada Y., Nakamura T., Nakayama A., Takada T., Kitajiri S., Wakai K., Suzuki H. and Shinomiya N.
  • Journal Title: Drug Metab Pharmacokinet Volume: 29 Pages: 490-492
  • DOI: 10.2133/dmpk.DMPK-14-SC-041
  • Peer Reviewed
• [Journal Article] Newly established ELISA for N-ERC/mesothelin improves diagnostic accuracy in patients with suspected pleural mesothelioma (2014)
  • Author(s): Sato, T., Suzuki Y., Mori T., Maeda M., Abe M., Hino O. and Takahashi K.
  • Journal Title: Cancer Med Volume: 3 Pages: 1377-1384
  • DOI: 10.1002/cam4.297
  • Peer Reviewed
• [Journal Article] The construction of risk prediction models using GWAS data and its application to a type 2 diabetes prospective cohort (2014)
  • Author(s): Shigemizu, D., Abe T., Morizono T., Johnson T.A., Boroevich K.A., Hirakawa Y., Ninomiya T., Kiyohara Y., Kubo M., Nakamura Y., Maeda S. and Tsunoda T.
  • Journal Title: PLoS One Volume: 9 Pages: e92549
  • DOI: 10.1371/journal.pone.0092549
  • Peer Reviewed
• [Journal Article] Reprogramming suppresses premature senescence phenotypes of Werner syndromecells and maintains chromosomal stability over long-term culture (2014)
  • Author(s): Shimamoto, A., Kagawa H., Zensho K., Sera Y., Kazuki Y., Osaki M., Oshimura M., Ishigaki Y., Hamasaki K., Kodama Y., Yuasa S., Fukuda K., Hirashima K., Seimiya H., Koyama H., Shimizu T., Takemoto M., Yokote K., Goto M. and Tahara H.
  • Journal Title: PLoS One Volume: 9 Pages: e112900
  • DOI: 10.1371/journal.pone.0112900
  • Peer Reviewed
• [Journal Article] Gender-specific associations of perceived stress and coping strategies with C-reactive protein in middle-aged and older men and women (2014)
  • Author(s): Shimanoe, C., Otsuka Y., Hara M., Nanri H., Nishida Y., Nakamura K., Higaki Y., Imaizumi T., Taguchi N., Sakamoto T., Horita M., Shinchi K. and Tanaka K.
  • Journal Title: Int J Behav Med Volume: 21 Pages: 821-832
  • DOI: 10.1007/s12529-013-9341-y
  • Peer Reviewed
• [Journal Article] Pharmaceutical and nutraceutical approaches for preventing liver carcinogenesis : chemoprevention of hepatocellular carcinoma using acyclic retinoid and branched-chain amino acids (2014)
  • Author(s): Shimizu, M., Shirakami Y., Hanai T., Imai K., Suetsugu A., Takai K., Shiraki M. and Moriwaki H.
  • Journal Title: Mol Nutr Food Res Volume: 58 Pages: 124-135
  • DOI: 10.1002/mnfr.201300538
  • Peer Reviewed
• [Journal Article] Impaired 8-hydroxyguanine repair activity of MUTYH variant p. Arg109Trp found in a Japanese patient with early-onset colorectal cancer (2014)
  • Author(s): Shinmura, K., Goto M., Tao H., Kato H., Suzuki R., Nakamura S., Matsuda T., Yin G., Morita M., Kono S. and Sugimura H.
  • Journal Title: Oxid Med Cell Longev Volume: 2014 Pages: 617351
  • DOI: 10.1155/2014/617351
  • Peer Reviewed
• [Journal Article] RSPO fusion transcripts in colorectal cancer in Japanese population (2014)
  • Author(s): Shinmura, K., Kahyo T., Kato H., Igarashi H., Matsuura S., Nakamura S., Kurachi K., Nakamura T., Ogawa H., Funai K., Tanahashi M., Niwa H. and Sugimura H.
  • Journal Title: Mol Biol Rep Volume: 41 Pages: 5375-5384
  • DOI: 10.1007/s11033-014-3409-x
  • Peer Reviewed
• [Journal Article] PLK4 overexpression and its effect on centrosome regulation and chromosome stability in human gastric cancer (2014)
  • Author(s): Shinmura, K., Kurabe N., Goto M., Yamada H., Natsume H., Konno H. and Sugimura H.
  • Journal Title: Mol Biol Rep Volume: 41 Pages: 6635-6644
  • DOI: 10.1007/s11033-014-3546-2
  • Peer Reviewed
• [Journal Article] Transgenic expression of the N525S-tuberin variant in Tsc2 mutant (Eker) rats causes dominant embryonic lethality (2014)
  • Author(s): Shiono, M., Kobayashi T., Takahashi R., Ueda M., Ishioka C. and Hino O
  • Journal Title: Sci Rep Volume: 4 Pages: 5927
  • DOI: 10.1038/srep05927
  • Peer Reviewed
• [Journal Article] The oncological outcomes and risk stratification in docetaxel chemotherapy for castration-resistant prostate cancer (2014)
  • Author(s): Shiota, M., Yokomizo A., Adachi T., Koga H., Yamaguchi A., Imada K., Takeuchi A., Kiyoshima K., Inokuchi J., Tatsugami K. and Naito S.
  • Journal Title: Jpn J Clin Oncol Volume: 44 Pages: 860-867
  • DOI: 10.1093/jjco/hyu081
  • Peer Reviewed
• [Journal Article] The feature of metabolic syndrome is a risk factor for biochemical recurrence after radical prostatectomy (2014)
  • Author(s): Shiota, M., Yokomizo A., Takeuchi A., Imada K., Kiyoshima K., Inokuchi J., Tatsugami K. and Naito S.
  • Journal Title: J Surg Oncol Volume: 110 Pages: 476-481
  • DOI: 10.1002/jso.23677
  • Peer Reviewed
• [Journal Article] Risk factors for febrile neutropenia in patients receiving docetaxel chemotherapy for castration-resistant prostate cancer (2014)
  • Author(s): Shiota, M., Yokomizo A., Takeuchi A., Imada K., Kiyoshima K., Inokuchi J., Tatsugami K. and Naito S.
  • Journal Title: Support Care Cancer Volume: 22 Pages: 3219-3226
  • DOI: 10.1007/s00520-014-2328-7
  • Peer Reviewed
• [Journal Article] Integrated analysis of whole genome and transcriptome sequencing reveals diverse transcriptomic aberrations driven by somatic genomic changes in liver cancers (2014)
  • Author(s): Shiraishi, Y., Fujimoto A., Furuta M., Tanaka H., Chiba K., Boroevich K.A., Abe T., Kawakami Y., Ueno M., Gotoh K., Ariizumi S., Shibuya T., Nakano K., Sasaki A., Maejima K., Kitada R., Hayami S., Shigekawa Y., Marubashi S., Yamada T., et al.
  • Journal Title: PLoS One Volume: 9 Pages: e114263
  • DOI: 10.1371/journal.pone.0114263
  • Peer Reviewed
• [Journal Article] Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation (2014)
  • Author(s): Sinner, M.F., Tucker N.R., Lunetta K.L., Ozaki K., Smith J.G., Trompet S., Bis J.C., Lin H., Chung M.K., Nielsen J.B., Lubitz S.A., Krijthe B.P., Magnani J.W., Ye J., Tsunoda T., Kubo M., Ebana Y., Furukawa T., Isobe M., Tanaka T., et al.
  • Journal Title: Circulation Volume: 130 Pages: 1225-1235
  • DOI: 10.1161/CIRCULATIONAHA.114.009892
  • Peer Reviewed
• [Journal Article] Subtypes of metabolic syndrome and of other risk factors in Japanese women with erosive esophagitis (2014)
  • Author(s): Sogabe, M., Okahisa T., Yamanoi A. and Takayama T.
  • Journal Title: Medicine (Baltimore) Volume: 93 Pages: e276
  • DOI: 10.1097/MD.0000000000000276
  • Peer Reviewed
• [Journal Article] TCGA output and practice of gastric cancer (2014)
  • Author(s): Sugimura, H
  • Journal Title: Translational Gastrointestinal Cancer
  • Description: Publish Ahead of Print
  • Peer Reviewed
• [Journal Article] Counts of Slackia sp. strain NATTS in intestinal flora are correlated to serum concentrations of equol both in prostate cancer cases and controls in Japanese men (2014)
  • Author(s): Sugiyama, Y., Nagata Y., Fukuta F., Takayanagi A., Masumori N., Tsukamoto T., Akasaka H., Ohnishi H., Saito S., Miura T., Moriyama K., Tsuji H., Akaza H. and Mori M.
  • Journal Title: Asian Pac J Cancer Prev Volume: 15 Pages: 2693-2697
  • Peer Reviewed
• [Journal Article] A rare Japanese case with a NUT midline carcinoma in the nasal cavity : a case report with immunohistochemical and genetic analyses (2014)
  • Author(s): Suzuki, S., Kurabe N., Minato H., Ohkubo A., Ohnishi I., Tanioka F. and Sugimura H.
  • Journal Title: Pathol Res Pract Volume: 210 Pages: 383-388
  • DOI: 10.1016/j.prp.2014.01.013
  • Peer Reviewed
• [Journal Article] NSD3-NUT-expressing midline carcinoma of the lung : First characterization of primary cancer tissue (2014)
  • Author(s): Suzuki, S., Kurabe N., Ohnishi I., Yasuda K., Aoshima Y., Naito M., Tanioka F. and Sugimura H.
  • Journal Title: Pathol Res Pract
  • DOI: 10.1016/j.prp.2014.10.013
  • Description: Epub ahead of print
  • Peer Reviewed
• [Journal Article] Extensive goblet cell metaplasia of the peripheral lung may harbor precancerous molecular changes : comparison of two cases (2014)
  • Author(s): Tajima, S., Kurabe N., Okudela K., Yajima K., Takahashi T., Neyatani H., Sugimura H. and Koda K.
  • Journal Title: Pathol Int Volume: 64 Pages: 533-538
  • DOI: 10.1111/pin.12204
  • Peer Reviewed
• [Journal Article] Radiation-induced breast angiosarcoma with a confirmative feature of c-MYC amplification (2014)
  • Author(s): Tajima, S., Mochizuki R., Sugimura H. and Hoshi S.
  • Journal Title: Jpn J Clin Oncol Volume: 44 Pages: 702-703
  • DOI: 10.1093/jjco/hyu064
  • Peer Reviewed
• [Journal Article] Advances in cancer epidemiology in Japan (2014)
  • Author(s): Tanaka, H.
  • Journal Title: Int J Cancer Volume: 134 Pages: 747-754
  • DOI: 10.1002/ijc.28519
  • Peer Reviewed
• [Journal Article] The biochemical recurrence-free rate in patients who underwent prostate low-dose-rate brachytherapy, using two different definitions (2014)
  • Author(s): Tanaka, N., Asakawa I., Katayama E., Hirayama A., Hasegawa M., Konishi N. and Fujimoto K.
  • Journal Title: Radiat Oncol Volume: 9 Pages: 107
  • DOI: 10.1186/1748-717X-9-107
  • Peer Reviewed
• [Journal Article] Use of alpha-1 adrenoceptor antagonists in patients who underwent low-dose-rate brachytherapy for prostate cancer-a randomized controlled trial of silodosin versus naftopidil (2014)
  • Author(s): Tanaka, N., Torimoto K., Asakawa I., Miyake M., Anai S., Hirayama A., Hasegawa M., Konishi N. and Fujimoto K.
  • Journal Title: Radiat Oncol Volume: 9 Pages: 1163
  • DOI: 10.1186/s13014-014-0302-7
  • Peer Reviewed
• [Journal Article] Nadir PSA level and time to nadir PSA are prognostic factors in patients with metastatic prostate cancer (2014)
  • Author(s): Tomioka, A., Tanaka N., Yoshikawa M., Miyake M., Anai S., Chihara Y., Okajima E., Hirayama A., Hirao Y. and Fujimoto K.
  • Journal Title: BMC Urol Volume: 14 Pages: 33
  • DOI: 10.1186/1471-2490-14-33
  • Peer Reviewed
• [Journal Article] Utility of PAX8 mouse monoclonal antibody in the diagnosis of thyroid, thymic, pleural and lung tumours : a comparison with polyclonal PAX8 antibody (2014)
  • Author(s): Toriyama, A., Mori T., Sekine S., Yoshida A., Hino O. and Tsuta K.
  • Journal Title: Histopathology Volume: 65 Pages: 465-472
  • DOI: 10.1111/his.12405
  • Peer Reviewed
• [Journal Article] Body mass index and breast cancer risk in Japan : a pooled analysis of eight population-based cohort studies (2014)
  • Author(s): Wada, K., Nagata C., Tamakoshi A., Matsuo K., Oze I., Wakai K., Tsuji I., Sugawara Y., Mizoue T., Tanaka K., Iwasaki M., Inoue M., Tsugane S., Sasazuki S., Research Group for the D. and Evaluation of Cancer Prevention Strategies in Japan
  • Journal Title: Ann Oncol Volume: 25 Pages: 519-524
  • DOI: 10.1093/annonc/mdt542
  • Peer Reviewed
• [Journal Article] Sugars, sucrose and colorectal cancer risk : the Fukuoka colorectal cancer study (2014)
  • Author(s): Wang, Z., Uchida K., Ohnaka K., Morita M., Toyomura K., Kono S., Ueki T., Tanaka M., Kakeji Y., Maehara Y., Okamura T., Ikejiri K., Futami K., Maekawa T., YasunamiY., Takenaka K., Ichimiya H. and Terasaka R.
  • Journal Title: Scand J Gastroenterol Volume: 49 Pages: 581-588
  • DOI: 10.3109/00365521.2013.822091
  • Peer Reviewed
• [Journal Article] Imputation and subset-based association analysis across different cancertypes identifies multiple independent risk loci in the TERT-CLPTMIL region onchromosome 5p15.33 (2014)
  • Author(s): Wang, Z., Zhu B., Zhang M., Parikh H., Jia J., Chung C.C., Sampson J.N., Hoskins J.W., Hutchinson A., Burdette L., Ibrahim A., Ito H., Kitahara C.M., Kohno T., Kunitoh H., Matsuo K., Niwa S., Shiraishi K., Tanaka H., Yatabe Y., et al.
  • Journal Title: Hum Mol Genet Volume: 23 Pages: 6616-6633
  • DOI: 10.1093/hmg/ddu363
  • Peer Reviewed
• [Journal Article] Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index (2014)
  • Author(s): Wen, W., Zheng W., Okada Y., Takeuchi F., Tabara Y., Hwang J.Y., Dorajoo R., Li H., Tsai F.J., Kubo M., Yamamoto K., Ohkubo T., Tsunoda T., Akiyama K., Takashima N., Isomura M., Umemura S., Isono M., Takayanagi R., Kang D.H., et al.
  • Journal Title: Hum Mol Genet Volume: 23 Pages: 5492-5504
  • DOI: 10.1093/hmg/ddu248
  • Peer Reviewed
• [Journal Article] Sexy Small Copy Numbers in Hereditary Gastric Carcinogenesis (2014)
  • Author(s): Yamada, H., Sakamoto H. and Sugimura H.
  • Journal Title: J of Gastrointestinal & Digestive System Volume: 4 Pages: 205
  • DOI: 10.4172/2161-069X.1000205
  • Peer Reviewed
• [Journal Article] A rare polymorphic variant of NBS1 reduces DNA repair activity and elevates chromosomal instability (2014)
  • Author(s): Yamamoto, Y., Miyamoto M., Tatsuda D., Kubo M., Nakagama H., Nakamura Y., Satoh H., Matsuda K., Watanabe T. and Ohta T.
  • Journal Title: Cancer Res Volume: 74 Pages: 3707-3715
  • DOI: 10.1158/0008-5472.CAN-13-3037
  • Peer Reviewed
• [Journal Article] Generation of human induced pluripotent stem (Ips) cells in serum- and feeder-free defined culture and TGF-Betal regulation of pluripotency (2014)
  • Author(s): Yamasaki, S., Taguchi Y., Shimamoto A., Mukasa H., Tahara H. and Okamoto T.
  • Journal Title: PLoS One Volume: 9 Pages: e87151
  • DOI: 10.1371/journal.pone.0087151
  • Peer Reviewed
• [Journal Article] Activation of Rheb, but not of mTORC1, impairs spine synapse morphogenesis in tuberous sclerosis complex (2014)
  • Author(s): Yasuda, S., Sugiura H., Katsurabayashi S., Shimada T., Tanaka H., Takasaki K., Iwasaki K., Kobayashi T., Hino O. and Yamagata K.
  • Journal Title: Sci Rep Volume: 4 Pages: 5155
  • DOI: 10.1038/srep05155
  • Peer Reviewed
• [Journal Article] Decreased amyloid-beta Pathologies by intracerebral loading of glycosphingolipid-enriched exosomes in Alzheimer model mice (2014)
  • Author(s): Yuyama, K., Sun H., Sakai S., Mitsutake S., Okada M., Tahara H., Furukawa J., Fujitani N., Shinohara Y. and Igarashi Y.
  • Journal Title: J Biol Chem Volume: 289 Pages: 24488-24498
  • DOI: 10.1074/jbc.M114.577213
  • Peer Reviewed
• [Journal Article] Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk (2014)
  • Author(s): Zhang, B., Jia W.H., Matsuda K., Kweon S.S., Matsuo K., Xiang Y.B., Shin A., Jee S.H., Kim D.H., Cai Q., Long J., Shi J., Wen W., Takahashi A., Matsuda F., Genetics, Epidemiology of Colorectal Cancer Consortium, Colorectal Transdisciplinary Study, Colon Cancer Family Registry, Hosono S., et al.
  • Journal Title: Nat Genet Volume: 46 Pages: 533-542
  • DOI: 10.1038/ng.2985
  • Peer Reviewed
• [Journal Article] Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians (2014)
  • Author(s): Zhang, B., Jia W.H., Matsuo K., Shin A., Xiang Y.B., Matsuda K., Jee S.H., Kim D.H., Cheah P.Y., Ren Z., Cai Q., Long J., Shi J., Wen W., Yang G., Ji B.T., Pan Z.Z., Matsuda F., Kubo M., Hosono S., et al.
  • Journal Title: Int J Cancer Volume: 135 Pages: 948-955
  • DOI: 10.1002/ijc.28733
  • Peer Reviewed
• [Journal Article] Burden of total and cause-specific mortality related to tobacco smoking among adults aged ≥ 45 years in Asia : a pooled analysis of 21 cohorts (2014)
  • Author(s): Zheng, W., McLerran D.F., Rolland B.A., Fu Z., Boffetta P., Tsugane S., Irie F., Tamakoshi A., Shu X.O., Ozasa K., Nishino Y., Tsuji I., Tanaka H., Sawada N., Ohishi W., Kakizaki M., Watanabe T., Oze I., Sugawara Y., Matsuo K., et al.
  • Journal Title: PLoS Med Volume: 11 Pages: e1001631
  • DOI: 10.1371/journal.Pmed.1001631
  • Peer Reviewed
• [Journal Article] クルクミンによるaryl hydrocarbon receptor(AhR)を介した発癌抑制機構 (2014)
  • Author(s): 井手久満、陸彦、杉浦正一郎、堀内明、古謝将之、中島晶子、井上正浩、野間康央、北村香介、常盤紫野、斎藤恵介、吉井隆、磯谷周治、山口雷藏、武藤智、堀江重郎
  • Journal Title: 日本腎泌尿器科疾患予防医学研究会誌 Volume: 22 Pages: 35-37
• [Journal Article] 統計家の行動基準の策定-背景と今後の課題 (2014)
  • Author(s): 佐藤恵子、岩崎学、菅波秀規、佐藤俊哉、椿広計
  • Journal Title: 計量生物学 Volume: 35 Pages: 37-53
  • DOI: 10.5691/jjb.35.37
  • Peer Reviewed
• [Journal Article] バイオバンクにおける同意撤回の自由と不帰投点(Point of No Return) (2014)
  • Author(s): 松井健志、會澤久仁子、玉腰暁子
  • Journal Title: 臨床薬理 Volume: 45 Pages: 17-23
  • DOI: 10.3999/jscpt.45.17
  • Peer Reviewed
• [Journal Article] 前立腺癌におけるがん幹細胞研究(特集去勢抵抗性前立腺癌 : 基礎と臨床の最新研究動向)--(前立腺癌の最新情報) (2014)
  • Author(s): 西田幸代、舛森直哉
  • Journal Title: 日本臨床 Volume: 72 Pages: 2229-2233
• [Journal Article] バイオバンク (2014)
  • Author(s): 増井徹
  • Journal Title: シリーズ生命倫理学 Volume: 11「遺伝子と医療」 Pages: 188-203
  • Description: (丸善出版)
• [Journal Article] ヒトゲノム研究の規制について : ゲノム情報の利用に焦点をあてて (2014)
  • Author(s): 増井徹
  • Journal Title: Organ Biology Volume: 21 Pages: 16-23
  • DOI: 10.11378/organbio.21.16
• [Journal Article] 遺伝子診断の未来と罠 (2014)
  • Author(s): 増井徹、齋藤加代子、菅野純夫
  • Journal Title: こころの科学 Volume: 増刊 Pages: 1-156
  • Description: (日本評論社)
• [Journal Article] 日本人閉経女性における肥満と骨質に関する検討(第15回日本骨粗鬆症学会) (2014)
  • Author(s): 尾崎悦子、栗山長門、松井大輔
  • Journal Title: オステオポローシスジャパン : 日本骨粗鬆症学会雑誌 Volume: 22 Pages: 465-468
  • Peer Reviewed
• [Journal Article] HTLV-1 induces a Thl-like state in CD4+CCR4+T cells (2014)
  • Author(s): N. Araya, T. Sato, H. Ando, U. Tomaru, M. Yoshida, A. Coler-Reilly, N. Yagishita, J. Yamauchi, A. Hasegawa, M. Kannagi, Y. Hasegawa, K. Takahashi, Y. Kunitomo, Y. Tanaka, T. Nakajima, K. Nishioka, A. Utsunomiya, S. Jacobson, Y. Yamano
  • Journal Title: J Clin Invest Volume: 124 Issue: 8 Pages: 3431-42
  • DOI: 10.1172/JCI75250
  • Peer Reviewed
• [Journal Article] Antitumor effects of bevacizumab in a microenvironment-dependent human adult T-cell leukemia/lymphoma mouse model (2014)
  • Author(s): Mori, F., Ishida, T., Ito, A., Sato, F., Masaki, A., Narita, T., Suzuki, S., Yamada, T., Takino, H., Ri, M., Kusumoto, S., Komatsu, H., Hishizawa, M., Imada, K., Takaori-Kondo, A., Niimi, A., Ueda, R., Inagaki, H. & Iida, S.
  • Journal Title: European journal of haematology Volume: 92 Pages: 219-228
  • DOI: 10.1111/ejh.12231
  • Peer Reviewed
• [Journal Article] Reactivation of hepatitis B virus in a patient with adult T-cell leukemia-lymphoma receiving the anti-CC chemokine receptor 4 antibody mogamulizumab (2014)
  • Author(s): Nakano, N., Kusumoto, S., Tanaka, Y., Ishida, T., Takeuchi, S., Takatsuka, Y., Akinaga, S., Mizokami, M., Ueda, R. & Utsunomiya, A.
  • Journal Title: Hepatology research : the official journal of the Japan Society of Hepatology Volume: 44 Pages: 354-357
  • DOI: 10.1111/hepr.12117
  • Peer Reviewed
• [Journal Article] HTLV-1 bZIP factor-specific CD4 T cell responses in adult T cell leukemia/lymphoma patients after allogeneic hematopoietic stem cell transplantation (2014)
  • Author(s): Narita, T., Ishida, T., Masaki, A., Suzuki, S., Ito, A., Mori, F., Yamada, T., Ri, M., Kusumoto, S., Komatsu, H., Miyazaki, Y., Takatsuka, Y., Utsunomiya, A., Niimi, A., Iida, S. & Ueda, R.
  • Journal Title: Journal of immunology Volume: 192 Pages: 940-947
  • DOI: 10.4049/jimmunol.1301952
  • Peer Reviewed
• [Journal Article] Prognostic impact of microRNA-145 down-regulation in adult T-cell leukemia/lymphoma (2014)
  • Author(s): Xia, H., Yamada, S., Aoyama, M., Sato, F., Masaki, A., Ge, Y., Ri, M., Ishida, T., Ueda, R., Utsunomiya, A., Asai, K. & Inagaki, H.
  • Journal Title: Human pathology Volume: 45 Pages: 1192-1198
  • DOI: 10.1016/j.humpath.2014.01.017
  • Peer Reviewed
• [Journal Article] HTLV-1 proviral integration sites differ between asymptomatic carriers and patients with HAM/TSP (2014)
  • Author(s): Niederer HA, Laydon DJ, Melamed A, Elemans M, Asquith B, Matsuoka M, Bangham CR
  • Journal Title: Virology J Volume: 11 Pages: 172
  • DOI: 10.1186/1743-422X-11-172
  • Peer Reviewed
• [Journal Article] A critical role for IL-17RB signaling in HTLV-1 Tax-induced NF-κB activation and T-cell transformation (2014)
  • Author(s): Lavorgna A, Matsuoka M, Harhaj EW
  • Journal Title: PLoS Pathogens Volume: 10 Pages: e1004418
  • DOI: 10.1371/journal.ppat.1004418
  • Peer Reviewed
• [Journal Article] The role of HTLV-1 clonality, proviral structure and genomic integration site in adult T cell leukemia/lymphoma (2014)
  • Author(s): Cook LB, Melamed A, Niederer H, Valganon M, Laydon D, Foroni L, Taylor GP, Matsuoka M, Bangham CR
  • Journal Title: Blood Volume: 123 Pages: 3925-3931
  • DOI: 10.1182/blood-2014-02-553602
  • Peer Reviewed
• [Journal Article] Development of T cell lymphoma in HTLV-1 bZIP factor and Tax double transgenic mice (2014)
  • Author(s): Zhao, T, Satou Y and Matsuoka M
  • Journal Title: Arch Virol Volume: 159 Pages: 1849-1856
  • DOI: 10.1007/s00705-014-2099-y
  • Peer Reviewed
• [Journal Article] Controlling leucine-zipper partner recognition in cells through modifications of a-g interactions (2014)
  • Author(s): Azuma Y, Kukenshöner T, Ma G, Yasunaga JI, Imanishi M, Arndt KM, Matsuoka M, and Futaki S
  • Journal Title: Chem. Commun. Volume: 50 Pages: 6364-6367
  • DOI: 10.1039/c4cc00555d
  • Peer Reviewed
• [Journal Article] HTLV-1 bZIP factor suppresses apoptosis by attenuating the function of Fox03a and altering its localization (2014)
  • Author(s): Tanaka-Nakanishi A, Yasunaga J-I, Takai K and Matsuoka M
  • Journal Title: Cancer Res Volume: 74 Pages: 188-200
  • DOI: 10.1158/0008-5472.CAN-13-0436
  • Peer Reviewed
• [Journal Article] Human T-cell leukemia virus type 1 and Foxp3 expression : viral strategy in vivo (2014)
  • Author(s): Miyazato P and Matsuoka M
  • Journal Title: Int Immunol Volume: 26 Pages: 419-425
  • DOI: 10.1093/intimm/dxu048
  • Peer Reviewed
• [Journal Article] Cytotoxic T lymphocyte lysis of HTLV-1 infected cells is limited by weak HBZ protein expression, but non-specifically enhanced on induction of Tax expression (2014)
  • Author(s): Rowan AG, Suemori K, Fujiwara H, Yasukawa M, Tanaka Y, Taylor GP, Bangham C
  • Journal Title: Retrovirology Volume: 11 Issue: 1 Pages: 116
  • DOI: 10.1186/s12977-014-0116-6
  • Peer Reviewed
• [Journal Article] Downregulation of proapoptotic Bim augments IL-2-independent T-cell transformation by human T-cell leukemia virus type-1 Tax (2014)
  • Author(s): Higuchi M, Takahashi M, Tanaka Y, Fujii M
  • Journal Title: Cancer Med Volume: 3 Issue: 6 Pages: 1605-14
  • DOI: 10.1002/cam4.329
  • Peer Reviewed
• [Journal Article] The neutralizing function of the anti-HTLV-1 antibody is essential in preventing in vivo transmission of HTLV-1 to human T cells in NOD-SCID/gammac null (NOG) mice (2014)
  • Author(s): Saito M, Tanaka R, Fujii H, Kodama A, Takahashi Y, Matsuzaki T, Takashima H, Tanaka Y
  • Journal Title: Retrovirology Volume: 11 Issue: 1 Pages: 74
  • DOI: 10.1186/s12977-014-0074-z
  • Peer Reviewed
• [Journal Article] Epigenetic deregulation of Ellis Van Creveld confers robust Hedgehog signaling in adult T-cell leukemia (2014)
  • Author(s): Takahashi R, Yamagishi M, Nakano K, Yamochi T, Yamochi T, Fujikawa D, Nakashima M, Tanaka Y, Uchimaru K, Utsunomiya A, Watanabe T
  • Journal Title: Cancer Sci Volume: 105 Issue: 9 Pages: 1160-9
  • DOI: 10.1111/cas.12480
  • Peer Reviewed
• [Journal Article] Epigenetic modification of the FoxP3 TSDR in HAM/TSP decreases the functional suppression of Tregs (2014)
  • Author(s): Anderson MR, Enose-Akahata Y, Massoud R, Ngouth N, Tanaka Y, Oh U, Jacobson S
  • Journal Title: J Neuroimmune Pharmacol Volume: 9 Issue: 4 Pages: 522-32
  • DOI: 10.1007/s11481-014-9547-z
  • Peer Reviewed
• [Journal Article] Elimination of human T cell leukemia virus type-l-infected cells by neutralizing and antibody-dependent cellular cytotoxicity-inducing antibodies against human t cell leukemia virus type-1 envelope gp46 (2014)
  • Author(s): Tanaka Y, Takahashi Y, Tanaka R, Kodama A, Fujii H, Hasegawa A, Kannagi M, Ansari AA, Saito M
  • Journal Title: AIDS Res Hum Retroviruses Volume: 30 Issue: 6 Pages: 542-52
  • DOI: 10.1089/AID.2013.0214
  • Peer Reviewed
• [Journal Article] HTLV-1キャリアが産生するウイルス構造蛋白質に対する抗体と末梢血中のプロウイルス量に関する解析 (2014)
  • Author(s): 井上由紀子, 守田麻衣子, 後藤信代, 相良康子, 入田和男, 矢持忠徳, 渡邉俊樹, 岩永正子, 浜口功, 清川博之
  • Journal Title: 日本輸血細胞治療学会誌 Volume: 60 Issue: 6 Pages: 592-599
  • Peer Reviewed
• [Journal Article] Development and validation of a new high-throughput method to investigate the clonality of HTLV-l-infected cells based on provirus integration sites (2014)
  • Author(s): Firouzi S, Lopez Y, Suzuki Y, Nakai K, Sugano S, Yamochi T, Watanabe T
  • Journal Title: Genome Med Volume: 6 Issue: 6 Pages: 46
  • DOI: 10.1186/gm568
  • Peer Reviewed
• [Journal Article] CADM1 expression and stepwise downregulation of CD7 are closely associated with clonal expansion of HTLV-1-infected cells in adult T-cell leukemia/lymphoma (2014)
  • Author(s): Kobayashi S, Nakano K, Watanabe E, Ishigaki T, Ohno N, Yuji K, Oyaizu N, Asanuma S, Yamagishi M, Yamochi T, Watanabe N, Tojo A, Watanabe T, Uchimaru K
  • Journal Title: Clin Cancer Res Volume: 20 Issue: 11 Pages: 2851-2861
  • DOI: 10.1158/1078-0432.CCR-13-3169
  • Peer Reviewed
• [Journal Article] High level of serum soluble interleukin-2 receptor at transplantation predicts poor outcome of allogeneic stem cell transplantation for adult T-cell leukemia (2014)
  • Author(s): Shigematsu A, Kobayashi N, Yasui H, Shindo M, Kakinoki Y, Koda K, Iyama S, Kuroda H, Tsutsumi Y, Imamura M, Teshima T
  • Journal Title: Biol Blood Marrow Transplant Volume: 20 Pages: 801-805
  • DOI: 10.1016/j.bbmt.2014.02.014
  • Peer Reviewed
• [Journal Article] Epstein-Barr virus-infected cells in IgG4-related lymphadenopathy with comparison to extranodal IgG4-related disease (2014)
  • Author(s): Takeuchi M, Sato Y, Yasui H, Ozawa H, Ohno K, Takata K, Iwaki N, Orita Y, Asano N, Nakamura S, Swerdlow SH, Yoshino T
  • Journal Title: Am J Surg Pathol Volume: 38 Pages: 946-955
  • DOI: 10.1097/PAS.0000000000000206
  • Peer Reviewed
• [Journal Article] Cancer-associated fibroblast-targeted strategy enhances antitumor immune responses in the dendritic cell-based vaccine (2014)
  • Author(s): Ohshio Y, Teramoto K, Hanaoka J, Tezuka N, Itoh Y, Asai T, Daigo Y, Ogasawara K
  • Journal Title: Cancer Sci
  • DOI: 10.1111/cas.12584
  • Description: [Epub ahead of print]
  • Peer Reviewed
• [Journal Article] Clinicopathological features and EGFR gene mutation status in elderly patients with resected non-small-cell lung cancer (2014)
  • Author(s): Nishii T, Yokose T, Miyagi Y, Daigo Y, Ito H, Isaka T, Imai K, Murakami S, Kondo T, Saito H, Oshita F, Yamada K, Matsukuma S, Tsuboi M, Nakayama H, Masuda M
  • Journal Title: BMC Cancer Volume: 14 Pages: 610
  • DOI: 10.1186/1471-2407-14-610
  • Peer Reviewed
• [Journal Article] Identification of a nuclear protein LRRC42 involved in lung pulmonary carcinogenesis (2014)
  • Author(s): Fujitomo T, Daigo Y, Matsuda K, Ueda K, Nakamura Y
  • Journal Title: Int J Oncol Volume: 45 Pages: 147-56
  • DOI: 10.3892/ijo.2014.2418
  • Peer Reviewed
• [Journal Article] Identification of immunogenic LY6K long peptide encompassing both CD4+ and CD8+ T-cell epitopes and eliciting CD4+ T-cell immunity in patients with malignant disease (2014)
  • Author(s): Tomita Y, Yuno A, Tsukamoto H, Senju S, Kuroda Y, Hirayama M, Imamura Y, Yatsuda J, Mohammad Abu Sayem, Irie A, Hamada A, Jono H, Yoshida K, Tsunoda T, Daigo Y, Kohrogi H, Yoshitake Y, Nakamura Y, Shinohara M, Nishimura Y.
  • Journal Title: Oncoimmunology Volume: 3 Pages: e28100
  • DOI: 10.4161/onci.28100
  • Peer Reviewed
• [Journal Article] Cell division cycle-associated protein 1 overexpression is essential for the malignant potential of colorectal cancers. (2014)
  • Author(s): Kobayashi Y, Takano A, Miyagi Y, Tsuchiya E, Sonoda H, Shimizu T, Okabe H, Tani T, Fujiyama Y, Daigo Y.
  • Journal Title: Int J Oncol Volume: 44 Pages: 69-77
  • DOI: 10.3892/ijo.2013.2177
  • Peer Reviewed
• [Journal Article] Proteomic Analysis of Proteins Related to Prognosis of Lung Adenocarcinoma. (2014)
  • Author(s): Okayama A, Miyagi Y, Oshita F, Nishi M, Nakamura Y, Nagashima Y, Akimoto K, Ryo A, Hirano H.
  • Journal Title: J Proteome Res Volume: 13 Issue: 11 Pages: 4686-94
  • DOI: 10.1021/pr4012969
  • Peer Reviewed
• [Journal Article] SIRT1 expression is associated with a poor prognosis, whereas DBC1 is associated with favorable outcomes in gastric cancer (2014)
  • Author(s): Noguchi A, Kikuchi K, Zheng H, Takahashi H, Miyagi Y, Aoki I, Takano Y.
  • Journal Title: Cancer Med Volume: 3 Issue: 6 Pages: 1553-61
  • DOI: 10.1002/cam4.310
  • Peer Reviewed
• [Journal Article] Angiomodulin, a marker of cancer vasculature, is upregulated by vascular endothelial growth factor and increases vascular permeability as a ligand of integrin αvβ3 (2014)
  • Author(s): Komiya E, Sato H, Watanabe N, Ise M, Higashi S, Miyagi Y, Miyazaki K
  • Journal Title: Cancer Med Volume: 3 Issue: 3 Pages: 537-49
  • DOI: 10.1002/cam4.216
  • Peer Reviewed
• [Journal Article] Lung adenocarcinoma subtypes definable by lung development-related miRNA expression profiles in association with clinicopathologic features (2014)
  • Author(s): Arima C, Kajino T, Tamada Y, Imoto S, ShimadaY, Nakatochi, M, Suzuki M, Isomura H, Yatabe Y, Yamaguchi T, Yanagisawa K, Miyano S, Takahashi T.
  • Journal Title: Carcinogenesis Volume: 35 Pages: 2224-2231
  • DOI: 10.1093/carcin/bgu127
  • Peer Reviewed
• [Journal Article] Expression of chromobox homolog 7 (CBX7) is associated with poor prognosis in ovarian clear cell adenocarcinoma via TRAIL-induced apoptotic pathway regulation. (2014)
  • Author(s): Shinjo K, Yamashita Y, Yamamoto E, Akatsuka S, Uno N, Kamiya A, Niimi K, Sakaguchi Y, Nagasaka T, Takahashi T, Shibata K, Kajiyama H, Kikkawa F, Toyokuni S.
  • Journal Title: Int J Cancer Volume: 135 Pages: 308-318
  • DOI: 10.1002/ijc.28692
  • Peer Reviewed
• [Journal Article] Tumor-derived Interleukin-1 promotes lymphangiogenesis and lymph node metastasis through M2-type macrophages (2014)
  • Author(s): Watari K, Shibata T, Kawahara A, Sata K, Nabeshima H, Shinoda A, Abe H, Azuma K, Murakami Y, Izumi, H, Takahashi T, Kage M, Kuwano M, Ono M.
  • Journal Title: PLoS ONE Volume: 9 Pages: e999568
  • DOI: 10.1371/journal.pone.0099568
  • Peer Reviewed
• [Journal Article] Cancer-promoting role of adipocytes in asbestos-induced mesothelial carcinogenesis through dysregulated adipocytokine production (2014)
  • Author(s): Chew SH, Okazaki Y, Nagai H, Misawa N, Akatsuka S, Yamashita K, Jiang L, Yamashita Y, Noguchi M, Hosoda K, Sekido Y, Takahashi T, Toyokuni S
  • Journal Title: Carcinogenesis Volume: 35 Pages: 164-172
  • DOI: 10.1093/carcin/bgt267
  • Peer Reviewed
• [Journal Article] Multimodal Effects of Small Molecule ROCK and LIMK Inhibitors on Mitosis, and Their Implication as Anti-Leukemia Agents (2014)
  • Author(s): Oku Y, Tareyanagi C, Takaya S, Osaka S, Ujiie H, Yoshida K, Nishiya N, Uehara Y.
  • Journal Title: PLoS One Volume: 9 Pages: e92402
  • DOI: 10.1371/journal.pone.0092402
  • Peer Reviewed
• [Journal Article] A zebrafish chemical suppressor screening identifies small molecule inhibitors of the Wnt/β-catenin pathway (2014)
  • Author(s): Nishiya N, Oku Y, Kumagai Y, Sato Y, Yamaguchi E, Sasaki A, Shoji M, Ohnishi Y, Okamoto H, Uehara Y.
  • Journal Title: Chemistry & Biology Volume: 12 Pages: 530-540
  • DOI: 10.1016/j.chembiol.2014.02.015
  • Peer Reviewed
• [Journal Article] Total synthesis of burkholdacs A and B and 5, 6, 20-tri-epi-burkholdac A : HDAC inhibition and antiproliferative activity (2014)
  • Author(s): Fukui Y, Narita K, Dan S, Yamori T, Ito A, Yoshida M, Katoh T
  • Journal Title: Eur. J. Med. Chem. Volume: 76 Pages: 301-313
  • DOI: 10.1016/j.ejmech.2014.02.044
  • Peer Reviewed
• [Journal Article] 5-Lipoxygenase and CysLTl regulate EGF-induced cell migration through Tiaml upregulation and Racl activation (2014)
  • Author(s): Magi S, Takemoto Y, Kobayashi H, Kasamatsu M, Akita T, Tanaka A, Takano K, Tashiro E, Igarashi Y, Imoto M
  • Journal Title: Cancer Sci Volume: 105 Pages: 290-296
  • DOI: 10.1111/cas.12340
  • Peer Reviewed
• [Journal Article] TRIBl supports prostate tumorigenesis and tumor-propagating cell survival by regulation of endoplasmic reticulum chaperone expression (2014)
  • Author(s): Mashima T, Soma-Nagae T, Migita T, Kinoshita R, Iwamoto A, Yuasa T, Yonese J, Ishikawa Y, Seimiya H
  • Journal Title: Cancer Res Volume: 74 Pages: 4888-4897
  • DOI: 10.1158/0008-5472.CAN-13-3718
  • Peer Reviewed
• [Journal Article] Inhibition of ATP citrate lyase induces triglyceride accumulation with altered fatty acid composition in cancer cells (2014)
  • Author(s): Migita T, Okabe S, Ikeda K, Igarashi S, Sugawara S, Tomida A, Soga T, Taguchi R, Seimiya H
  • Journal Title: Int J Cancer Volume: 135 Pages: 37-47
  • DOI: 10.1002/ijc.28652
  • Peer Reviewed
• [Journal Article] Xanthohumol suppresses oestrogen-signalling in breast cancer through the inhibition of BIG3-PHB2 interactions (2014)
  • Author(s): Yoshimaru T, Komatsu M, Tashiro E, Imoto M, Osada H, Miyoshi Y, Honda J, Sasa M, Katagiri T
  • Journal Title: Sci Rep Volume: 4 Pages: 7355
  • DOI: 10.1038/srep07355
  • Peer Reviewed
• [Journal Article] A small compound targeting TACC3 revealed its different spatiotemporal contributions for spindle assembly in cancer cells (2014)
  • Author(s): Yao R, Kondoh Y, Natsume Y, Yamanaka H, Inoue M, Toki H, Takagi R, Shimizu T, Yamori T, Osada H, Noda T
  • Journal Title: Oncogene Volume: 33 Issue: 33 Pages: 4242-4252
  • DOI: 10.1038/onc.2013.382
  • Peer Reviewed
• [Journal Article] Regulation of Tissue Factor Pathway Inhibitor-2 (TFPI-2) Expression by Lysine-Specific Demethylase 1 and 2 (LSD1 and LSD2) (2014)
  • Author(s): Mino K, Nishimura S, Ninomiya S, Tujii H, Matsumori Y, Tsuchida M, Hosoi M, Koseki K, Wada S, Hasegawa M, Sasaki R, Murakami-Yamaguchi Y, Narita H, Suzuki T, Miyata N, Mizukami T
  • Journal Title: Biosci Biotechnol Biochem Volume: 78 Issue: 6 Pages: 1010-1017
  • DOI: 10.1080/09168451.2014.910104
  • Peer Reviewed
• [Journal Article] Array-based genome-wide RNAi screening to identify shRNAs that enhance p53-related apoptosis in human cancer cells (2014)
  • Author(s): Idogawa M, Ohashi T, Sugisaka J, Sasaki Y, Suzuki H, Tokino T
  • Journal Title: Oncotarget Volume: 5 Issue: 17 Pages: 7540-7548
  • Peer Reviewed
• [Journal Article] Forkhead transcription factor FOXF1 is a novel target gene of the p53 family and regulates cancer cell migration and invasiveness (2014)
  • Author(s): Tamura M, Sasaki Y, Koyama R, Takeda K, Idogawa M, Tokino T
  • Journal Title: Oncogene Volume: 33 Issue: 40 Pages: 4837-4846
  • DOI: 10.1038/onc.2013.427
  • Peer Reviewed
• [Journal Article] Identification and analysis of large non-coding RNAs regulated by p53 family members through a genome-wide analysis of p53-binding sites (2014)
  • Author(s): Idogawa M, Ohashi T, Sasaki Y, Maruyama R, Kashima L, Suzuki H, Tokino T
  • Journal Title: Human Molecular Genetics Volume: 23 Issue: 11 Pages: 2847-2857
  • DOI: 10.1093/hmg/ddt673
  • Peer Reviewed
• [Journal Article] Silencing of microRNA-122 is an early event during hepatocarcinogenesis from non-alcoholic steatohepatitis (2014)
  • Author(s): Takaki Y, Saito Y, Takasugi A, Toshimitsu K, Yamada S, Muramatsu T, Kimura M, Sugiyama K, Suzuki H, Arai E, Ojima H, Kanai Y, Saito H
  • Journal Title: Cancer Sci Volume: 105 Pages: 1254-1260
  • DOI: 10.1111/cas.12498
  • Peer Reviewed
• [Presentation] マイクロRNAを用いたバイオマーカーおよび核酸医薬の開発 (2015)
  • Author(s): 田原栄俊
  • Organizer: 第59回分子病態医学セミナー&TRCセミナー合同セミナー
  • Place of Presentation: 愛媛大学(愛媛県・松山市)
  • Year and Date: 2015-04-03
• [Presentation] microRNAが切り拓く創薬研究の新展開について (2015)
  • Author(s): 田原栄俊
  • Organizer: 日本薬学会第135年会
  • Place of Presentation: 神戸学院大学(兵庫県・神戸市)
  • Year and Date: 2015-03-27
  • Invited
• [Presentation] テロメア・マイクロRNAを用いた疾患の予防と早期診断 (2015)
  • Author(s): 田原栄俊
  • Organizer: 第40回日本脳卒中学会総会
  • Place of Presentation: リーガロイヤルホテル広島(広島県・広島市)
  • Year and Date: 2015-03-27
  • Invited
• [Presentation] Clock遺伝子多型と糖尿病有病との関連について : J-MICC Studyより (2015)
  • Author(s): 上村浩一、山口美輪、釜野桜子、有澤孝吉、J-MICC Study Group
  • Organizer: 第85回日本衛生学会学術総会
  • Place of Presentation: 和歌山県民文化会館(和歌山県・和歌山市)
  • Year and Date: 2015-03-26 – 2015-03-28
• [Presentation] 細菌型チロシンキナーゼ阻害剤探索系の開発 (2015)
  • Author(s): 深澤秀輔、益見厚子
  • Organizer: 日本薬学会第135年会
  • Place of Presentation: 兵庫医療大学(兵庫県・神戸市)
  • Year and Date: 2015-03-26
• [Presentation] 遺伝子型cnmを有するS. mutans感染と脳内微小出血が関連する-歯科領域との新しい連携の可能性- (2015)
  • Author(s): 栗山長門, 水野敏樹、山田恵、渡邊能行
  • Organizer: 第40回脳卒中学会
  • Place of Presentation: リーガロイヤルホテル広島(広島県・広島市)
  • Year and Date: 2015-03-25
• [Presentation] Circulating miRNAs as liquid biopsy in Alzheimer's disease and pancreatic cancer toward application for the diagnosis (2015)
  • Author(s): Yu Ninose, Sayaka Okamoto, Ikuko Takeda, Tetsuya Takahashi, Masayasu Matsumoto
  • Organizer: Extracellular Biomarkers Summit
  • Place of Presentation: Hyatt Regency Cambridge, Boston, U.S.A.
  • Year and Date: 2015-03-16
• [Presentation] マイクロRNA・細胞外小胞がもたらす脳神経内科の未来 (2015)
  • Author(s): 田原栄俊
  • Organizer: 第13回脳神経内科ジョイントミーティング
  • Place of Presentation: リーガロイヤルホテル広島(広島県・広島市)
  • Year and Date: 2015-03-03
  • Invited
• [Presentation] 日本人non-CKDにおける血清FGF23濃度の決定因子と尿中アルブミン排泄(ACR)について」 (2015)
  • Author(s): 尾﨑悦子、稲葉雅章、山田真介、栗山長門、松井大輔、渡邉功、小山晃英、渡邊能行
  • Organizer: 第26回日本腎性骨症研究会
  • Place of Presentation: 品川プリンスホテル(東京)
  • Year and Date: 2015-02-21
• [Presentation] 腎細胞癌肺転移新規モデルの構築及び評価 (2015)
  • Author(s): 三島胡桃、山野荘太郎、山田健二、藤岡正喜、魏民、鰐渕英機
  • Organizer: 第14回分子予防環境医学研究会
  • Place of Presentation: 大阪市立大学(大阪府・大阪市)
  • Year and Date: 2015-02-13 – 2015-02-14
• [Presentation] 1,2-DCP投与によるハムスターおよびマウスの肝毒性メカニズムの検討 (2015)
  • Author(s): 下村衣里、魏民、藤岡正喜、山野荘太郎、梯アンナ、鰐渕英機
  • Organizer: 第14回分子予防環境医学研究会
  • Place of Presentation: 大阪市立大学(大阪府・大阪市)
  • Year and Date: 2015-02-13 – 2015-02-14
• [Presentation] 成人T細胞白血病の成り立ちと免疫療法 (2015)
  • Author(s): 神奈木真理
  • Organizer: 第64回日本輸血・細胞治療学会東海支部例会
  • Place of Presentation: 桑山ビル(愛知県・名古屋市)
  • Year and Date: 2015-02-07
  • Invited
• [Presentation] 腎発がんモデルを用いた発がん機構の解明及び転移モデルへの応用 (2015)
  • Author(s): 山野荘太郎、三島胡桃、山田健二、平山幸良、藤岡正喜、魏民、鰐渕英機
  • Organizer: 平成26年度「個体レベルでのがん研究支援活動」ワークショップ
  • Place of Presentation: 琵琶湖ホテル(滋賀県・大津市)
  • Year and Date: 2015-02-05 – 2015-02-06
• [Presentation] 肝微小環境が及ぼす転移性腎癌への影響 (2015)
  • Author(s): 平山幸良、山野荘太郎、山田健二、藤岡正喜、魏民、三島胡桃、鰐渕英機
  • Organizer: 平成26年度「個体レベルでのがん研究支援活動」ワークショップ
  • Place of Presentation: 琵琶湖ホテル(滋賀県・大津市)
  • Year and Date: 2015-02-05 – 2015-02-06
• [Presentation] 肺発がんの発育進展に関与する発がん促進・抑制作用について (2015)
  • Author(s): 今井田克己
  • Organizer: 平成26年度「個体レベルでのがん研究支援活動」ワークショップ
  • Place of Presentation: 琵琶湖ホテル(大津市・滋賀県)
  • Year and Date: 2015-02-05 – 2015-02-06
  • Invited
• [Presentation] ハムスターBOP二段階膵胆管発がんモデルを用いた1,2-dichloropropane(1,2-DCP)の発がん修飾作用の検討 (2015)
  • Author(s): 下村衣里、魏民、藤岡正喜、山野荘太郎、梯アンナ、鰐渕英機
  • Organizer: 第31回日本毒性病理学会学術総会及び学術集会
  • Place of Presentation: タワーホール船堀(東京)
  • Year and Date: 2015-01-29 – 2015-01-30
• [Presentation] CNPY2 and CACHD1 as novel molecular markers of hepatocellular carcinoma (2015)
  • Author(s): Anna Kakehashi, Naomi Ishii, Min Gi, Masaki Fujioka, Hideki Wanibuchi
  • Organizer: 第31回日本毒性病理学会学術総会及び学術集会
  • Place of Presentation: タワーホール船堀(東京)
  • Year and Date: 2015-01-29 – 2015-01-30
• [Presentation] 非遺伝毒性肝発がん物質ダンマル樹脂の発がんメカニズムの検討 (2015)
  • Author(s): 藤岡正喜、魏民、山野荘太郎、下村衣里、三島胡桃、鰐渕英機
  • Organizer: 第31回日本毒性病理学会学術総会及び学術集会
  • Place of Presentation: タワーホール船堀(東京)
  • Year and Date: 2015-01-29 – 2015-01-30
• [Presentation] ラット同所同種移植による新規腎癌肺転移モデルの確立及び評価 (2015)
  • Author(s): 三島胡桃、山野荘太郎、魏民、鰐渕英機
  • Organizer: 第31回日本毒性病理学会学術総会及び学術集会
  • Place of Presentation: タワーホール船堀(東京)
  • Year and Date: 2015-01-29 – 2015-01-30
• [Presentation] Comparison of dietary record procedures in calibration studies for two large cohort studies (2015)
  • Author(s): Imaeda N, Ishihara J, Takachi R, Goto C, Ishii Y, Kojima S, Nanri H, Nakamura K, Yamaguchi M, Tanaka J, Fukuda N, Iso H, Hosono S, Shimazu T, Miyagawa N, Sawada N, Wakai K, Sasazuki S, Tanaka H, Tsugane S
  • Organizer: 第25回日本疫学会学術総会
  • Place of Presentation: ウインクあいち(愛知県・名古屋市)
  • Year and Date: 2015-01-23
• [Presentation] ABCG2 gysfunction causes not only renal urate overload hyperuricemia but also renal-urate underexcretion hyperuricemia (2015)
  • Author(s): Matsuo H, Nakayama A, Sakiyama M, Chiba T, Shimazu S, Nakashima H, Nakamura T, Takada Y, Takada T, Nakaoka H, Wakai K, Kawai S, Tin G, Nakagawa H, Ito T, Yamamoto K, Sakurai Y, Ichida K, Shimizu T, Shinomiya N
  • Organizer: 第25回日本疫学会学術総会
  • Place of Presentation: ウインクあいち(愛知県・名古屋市)
  • Year and Date: 2015-01-23
• [Presentation] Genefic effect by dysfunctional variants of ABCG2 is tronger than environmental effects for hyperuricemia (2015)
  • Author(s): Nakayama A, Matsuo H, Nakaoka H, Nakamura T, Nakashima H, Takada Y, Oikawa Y, Takada T, Sakiyama M, Shimizu S, Chiba T, Wakai K, Kawai S, Okada R, Tamura T, Shichijo Y, Akashi A, Sakurai Y, Ichida K, Shinomiya N
  • Organizer: 第25回日本疫学会学術総会
  • Place of Presentation: ウインクあいち(愛知県・名古屋市)
  • Year and Date: 2015-01-23
• [Presentation] Clinical and Lifestyle Characteristics associated with HTLV-1 Carrier among General Population (2015)
  • Author(s): Tara Sefanya Kairupan, Rie Ibusuki, Eva Mariane Mantjoro, Hideshi Niimura, Kazuyo Kuwabara, Shin Ogawa, Noriko Nakahata, Yasuhito Nerome, Tetsuhiro Ohwaki, Ken Kusano, Toshiro Takezaki
  • Organizer: 第24回日本疫学会学術総会
  • Place of Presentation: ウインクあいち(愛知県・名古屋市)
  • Year and Date: 2015-01-23
• [Presentation] Association of an EPAS1 gene polymorphism with susceptibility to lung adenocarcinoma in female Japanese non-smokers (2015)
  • Author(s): Hidetaka Eguchi, Shinichi Iwamoto, Yumi Nishio, Andica Chandra Putra, Hiroshi Fuchita, Miki Ohe, Akihisa Sutani, Takashige Kuraki, Keiko Hiyama, Isao Murakami, Keiji Tanimoto, Takeshi Isobe
  • Organizer: 第25回日本疫学会学術総会
  • Place of Presentation: ウインクあいち(愛知県・名古屋市)
  • Year and Date: 2015-01-23
• [Presentation] SNP-set Kernet Association Test identifirld biological pathways associated with Japanese cedar and hinoki pollen allergy (2015)
  • Author(s): Hattori Y, Hishida A, Moirta E, Nakatochi M, Zhao N, Wu MC, Sasakabe T, Suma S, Okada R, Kawai S, Naito M, Hamajima N, Tanaka H, Wakai K
  • Organizer: 第25回日本疫学会学術総会
  • Place of Presentation: ウインクあいち(愛知県・名古屋市)
  • Year and Date: 2015-01-23
• [Presentation] A SNP-set Kernet Association Test detected genetic pathway involved in persistent Helicobacter pyloriinfection (2015)
  • Author(s): Hishida A, Zhao N, Wu MC, Nakatochi M, Naito M, Sasakabe T, Hattori Y, Suma S, Okada R, Kawai S, Morita E, Hamajima N, Tanaka H, Wakai K
  • Organizer: 第25回日本疫学会学術総会
  • Place of Presentation: ウインクあいち(愛知県・名古屋市)
  • Year and Date: 2015-01-23
• [Presentation] A20 interacts with Caspase-8 and FADD to protect adult T-cell leukemia cells (2015)
  • Author(s): 山岡昇司
  • Organizer: 2nd International Symposium on Protein Modefication in Pathogenic Dysregulation of Signaling
  • Place of Presentation: 東京大学医科学研究所(東京)
  • Year and Date: 2015-01-23
• [Presentation] Novel screening method for in vivo platelet activation in vascular dementia (2015)
  • Author(s): Kuriyama Nagato, Ozaki etsuko, Matsui Daisuke, Koyama Teruhide, Watanabe Isao, Watanabe Yoshiyuki
  • Organizer: 第25回日本疫学会
  • Place of Presentation: ウインクあいち(愛知県・名古屋市)
  • Year and Date: 2015-01-21 – 2015-01-23
• [Presentation] Association between moderate/vigorous intensity of physical activity and urinary levels of 8-hydroxydeoxyguanosine (2015)
  • Author(s): Hara M, Nishida Y, Shimanoe C, Otsuka Y, Nanri H, Higaki Y, Horita M, Kawai K, Li YS, Kasai J, Kasai H, Tanaka K
  • Organizer: 第25回日本疫学会学術総会
  • Place of Presentation: ウインクあいち(愛知県・名古屋市)
  • Year and Date: 2015-01-21 – 2015-01-23
• [Presentation] Significant interaction between ADIPOQ gene and higher BMI on HbAlc levels in a Japanese general population (2015)
  • Author(s): Shimanoe C, Higaki Y, Nishida Y, Hara M, Nanri H, Nakamura K, Imaizumi T, Sakamoto T, Taguchi N, Horita M, Shinchi K, Tanaka K, J-MICC Study Group
  • Organizer: 第25回日本疫学会学術総会
  • Place of Presentation: ウインクあいち(愛知県・名古屋市)
  • Year and Date: 2015-01-21 – 2015-01-23
• [Presentation] Association between objectively measured physical activity and serum adiponectin in the middle-agedpopulation (2015)
  • Author(s): Nishida Y, Higaki Y, Taguchi N, Hara M, Nakamura K, Nanri H, Imaizumi T, Sakamoto T, Shimanoe C, Horita M, Shinchi K, Tanaka K
  • Organizer: 第25回日本疫学会学術総会
  • Place of Presentation: ウインクあいち(愛知県・名古屋市)
  • Year and Date: 2015-01-21 – 2015-01-23
• [Presentation] HTLV-1の病原性発現機構とATLの発症機構 (2015)
  • Author(s): 渡邉俊樹
  • Organizer: 第5回病原微生物部門セミナー
  • Place of Presentation: 山口大学農学部(山口県・山口市)
  • Year and Date: 2015-01-20
  • Invited
• [Presentation] アスベスト誘発中皮腫発がんモデルの解析から予防および治療へ (2014)
  • Author(s): 豊國伸哉
  • Organizer: アスベスト関連疾患研究会
  • Place of Presentation: がん研究会がん研究所吉田富三記念講堂(東京)
  • Year and Date: 2014-12-27
  • Invited
• [Presentation] 骨転移巣を形成するがん細胞の悪性形質を規定するメカニズム (2014)
  • Author(s): 二口充
  • Organizer: 第28回骨代謝セミナー
  • Place of Presentation: 京王プラザホテル(東京)
  • Year and Date: 2014-12-19
  • Invited
• [Presentation] DNA adductomics in human tissue : a clue toward the origin of human cancer? (2014)
  • Author(s): Haruhiko Sugimura
  • Organizer: 4th Asian Conference on Environmental Mutagens
  • Place of Presentation: Kolkata, India
  • Year and Date: 2014-12-12
  • Invited
• [Presentation] Protection of newborns against human T cell leukemia virus type-1 (HTLV-1) infection by maternally-transmitted monoclonal anti-HTLV-1 gp46 antibody (2014)
  • Author(s): Fujii H, Shimizu M, Takahashi Y, Tanaka R, Tanaka Y
  • Organizer: 第43回日本免疫学会総会・学術集会
  • Place of Presentation: 国立京都国際会館(京都府・京都市)
  • Year and Date: 2014-12-11
• [Presentation] Evaluation of anti-gp46 neutralizing monoclonal antibody vaccine against primary HTLV-1 infection to rats (2014)
  • Author(s): Mukakami Y, Ando S, Tanaka Y, Tanaka R, Matsuda T, Kannagi M, Hasegawa A
  • Organizer: 第43回日本免疫学会総会・学術集会
  • Place of Presentation: 国立京都国際会館(京都府・京都市)
  • Year and Date: 2014-12-11
• [Presentation] CTL epitope peptide-pulsed dendritic cell vaccine has the potential torestore HTLV-1-specific CTLs to eliminate infected cells (2014)
  • Author(s): Ando S. Hasegawa A, Murakami Y, Takatsuka N, Maeda Y, Masuda T, Kannagi M
  • Organizer: 第43回日本免疫学会学術集会
  • Place of Presentation: 国立京都国際会館(京都府・京都市)
  • Year and Date: 2014-12-10 – 2014-12-12
• [Presentation] Evaluation of anti-gp46 neutralizing monoclonal antibody vaccine againstprimary HTLV-1 infection to rats (2014)
  • Author(s): Murakami Y, Ando S, Tanaka Y, Tanaka R, Masuda T, Kannagi M, Hasegawa A.
  • Organizer: 第43回日本免疫学会学術集会
  • Place of Presentation: 国立京都国際会館(京都府・京都市)
  • Year and Date: 2014-12-10 – 2014-12-12
• [Presentation] A link between HTLV-1 leukemogenesis and innate immunity ; involvement of PKR in the constitutive NFκB activation in adult T-cell leukemia cells (2014)
  • Author(s): Kinpara S, Saitoh Y, Hasegawa A, Nakamura M, Yamaoka S, Matsuoka M, Masuda T, Kannagi M.
  • Organizer: 第43回日本免疫学会学術集会
  • Place of Presentation: 国立京都国際会館、京都市
  • Year and Date: 2014-12-10 – 2014-12-12
• [Presentation] 閉経女性におけるカフェイン摂取と骨密度の検討 (2014)
  • Author(s): 尾﨑悦子、阪田亜実、弘田真央、瀬古千佳子、加藤里佳、渡邊能行
  • Organizer: 第13回日本栄養改善学会近畿地方会
  • Place of Presentation: 京都女子大学(京都府・京都市)
  • Year and Date: 2014-12-07
• [Presentation] Landscape of genetic alterations in adult T-cell leukemia/lymphoma (2014)
  • Author(s): Kataoka K, Nagata Y, Kitanaka A, Sato-Otsubo A, Totoki Y, Yasunaga J, Sanada M, Shiraishi Y, Chiba K, Tanaka H, Suzuki H, Sato Y, Shiozawa Y, Yoshizato T, Kon A, Yoshida K, Munakata W, Nakamura H, Hama N, Shide K, Kubuki Y, Hidaka T, Kameda T, Ishiyama K, Miyawaki S, Ishii R, Nureki 0, Nagae G, Aburatani H, Miyano S, Watanabe T, Matsuoka M, Shibata T, Shimoda K, Ogawa S.
  • Organizer: 56th of ASH Annual Meeting and Exposition
  • Place of Presentation: Moscone Center, San Francisco, U.S.A.
  • Year and Date: 2014-12-07
• [Presentation] Novel Biological Effects and Distinct Patterns of Rhoa Mutations in Adult T-Cell Leukemia/Lymphoma and Angioimmunoblastic T Cell Lymphoma (2014)
  • Author(s): Nagata Y, Enami T, Kontani K, Kataoka K, Sakata-Yanagimoto M, Kitanaka A, Sato A, Shiraishi Y, Chiba K, Tanaka H, Shiozawa Y, Yoshizato T, Kon A, Yoshida K, Sanada M, Ishiyama K, Miyawaki S, Ishii R, Nureki O, Miyano S, Shimoda K, Watanabe T, Katada T, Chiba S, Ogawa S
  • Organizer: 56th of ASH Annual Meeting and Exposition
  • Place of Presentation: Moscone Center, San Francisco, U.S.A.
  • Year and Date: 2014-12-07
• [Presentation] Rapidly changing causal factors of hepatocellular carcinoma(HCC)in Japan (2014)
  • Author(s): Hiroaki Kanda, Noriko Yamamoto, Akio Saiura, Yo Kato, Yuichi Ishikawa, Tomoyuki Kitagawa
  • Organizer: World cancer congress 2014
  • Place of Presentation: Melbourne, Australia
  • Year and Date: 2014-12-02 – 2014-12-07
• [Presentation] HTLV-1感染症に対する免疫療法 (2014)
  • Author(s): 神奈木真理
  • Organizer: 第4回沖縄ウイルス研究会
  • Place of Presentation: ANAクラウンプラザホテル(沖縄県・那覇市)
  • Year and Date: 2014-12-02
  • Invited
• [Presentation] Monitoring clonal composition of HTLV-1-infected cells based on provirus integration sites (2014)
  • Author(s): Sanaz Firouzi, Tadanori Yamochi, Osvany Lopez, Yutaka Suzuki, Kenta Nakai, Sumio Sugano, Toshiki Watanabe
  • Organizer: 第37回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-11-27
• [Presentation] アルツハイマー患者における血漿中マイクロRNAの解析と診断への応用, Analysis of circulating miRNAs in plasma from patients with Alzheimer's disease toward application for the diagnosis (2014)
  • Author(s): 二瀬由宇、岡田沙矢香、竹田育子、高橋哲也、松本昌泰、田原栄俊
  • Organizer: 第37回日本分子生物学会
  • Place of Presentation: パシフィコ横浜(神奈川県横浜市)
  • Year and Date: 2014-11-26
• [Presentation] 老化を調節するmicroRNAの膵臓がん細胞における機能解析, Analysis of senescence-associated miRNA that suppress pancreatic cancer (2014)
  • Author(s): 福永早央里、塩谷文章、嶋本顕、田原栄俊
  • Organizer: 第37回日本分子生物学会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-11-26
• [Presentation] microRNAによる細胞老化誘導機構の解明, Elucidation of mechanism underlying cellular senescence induced by miRNAs (2014)
  • Author(s): 山本佑樹、塩谷文章、嶋本顕、田原栄俊
  • Organizer: 第37回日本分子生物学会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-11-26
• [Presentation] Sirtuin 1選択的阻害活性をもつ新規2-hydroxy-1-naphthaldehyde誘導体とその抗がん活性 (2014)
  • Author(s): 瓦谷泰之、平田佳之、深田尚文、住吉孝明、長岡康夫、伊藤昭博、吉田稔、上里新一
  • Organizer: 第37回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-11-26
• [Presentation] MSM/Ms由来ES細胞を用いたc-MafトランスジェニックMSM/Msマウスラインの作出と解析 (2014)
  • Author(s): 昇地高雅, 舘山浩紀, 山村研一, 高橋智, 荒木喜美
  • Organizer: 第37回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-11-25 – 2014-11-27
• [Presentation] オートファジー不全と慢性膵炎発症メカニズムの解明 (2014)
  • Author(s): 大村谷昌樹, 坂田和也, 高城克暢, 松元美由紀, 荒木喜美, 山村研一
  • Organizer: 第37回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-11-25 – 2014-11-27
• [Presentation] CRISPR/Cas9による2本鎖切断・1本鎖切断を利用した場合のマウスES細胞における相同組換え効率の比較 (2014)
  • Author(s): 荒木喜美, 牟田真由美, 仙波圭, 竹田直樹, 仁木大輔, 松本健, 武田伊世, 山村研一, 大村谷昌樹, 荒木正健
  • Organizer: 第37回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-11-25 – 2014-11-27
• [Presentation] 大脳新皮質の細胞多様性の形成に必須なBrn転写因子の作用形式 (2014)
  • Author(s): 杉谷善信、杉谷玲子、中井茂康、美野輪治、小川正晴、野田哲生
  • Organizer: 第37回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-11-25
• [Presentation] 成人T細胞白血病におけるEZH2依存的エピジェネティック異常の包括的解析 (2014)
  • Author(s): 堀真琴、藤川大、中川翔太、田中勇悦、中野和民、渡邉俊樹、山岸誠
  • Organizer: 第37回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-11-25
• [Presentation] 心理ストレスおよび対処行動と血中バイオマーカーの関連 : J-MICC Study-SAGAによる疫学的検討 (2014)
  • Author(s): 島ノ江千里、原めぐみ、西田裕一郎、田中恵太郎
  • Organizer: 第21回日本行動医学会学術総会(シンポジウム)
  • Place of Presentation: 早稲田大学所沢キャンパス(埼玉県・所沢市)
  • Year and Date: 2014-11-22 – 2014-11-23
• [Presentation] 臨床診断研究支援活動によるがん研究支援と創薬に向けた展望 (2014)
  • Author(s): 醍醐弥太郎
  • Organizer: 第59回人類遺伝学会・第21回日本遺伝子診療学会合同大会シンボジウム
  • Place of Presentation: タワーホール船堀(東京)
  • Year and Date: 2014-11-22
• [Presentation] アスベストによる中皮腫発がん機構の解明からナノマテリアルのリスク評価ヘシンポジウム1 : 環境発がんのリスク評価における病理学の貢献 (2014)
  • Author(s): 豊國伸哉
  • Organizer: 第60回日本病理学会秋期特別総会
  • Place of Presentation: 国立劇場おきなわ(沖縄県・浦添市)
  • Year and Date: 2014-11-20 – 2014-11-21
  • Invited
• [Presentation] 環境発がんのリスク評価における病理学の貢献 (2014)
  • Author(s): 今井田克己
  • Organizer: 第60回日本病理学会秋期特別集会シンポジウム1
  • Place of Presentation: 国立劇場おきなわ(沖縄県・那覇市)
  • Year and Date: 2014-11-20 – 2014-11-21
  • Invited
• [Presentation] ヒ素の発がん機序の解明 (2014)
  • Author(s): 鰐渕英機、魏民
  • Organizer: 第60回日本病理学会秋期特別総会シンポジウム1
  • Place of Presentation: 国立劇場おきなわ(沖縄県・浦添市)
  • Year and Date: 2014-11-20
  • Invited
• [Presentation] ヒトiPSを活用した肝臓ヒト化マウスの作製と応用 (2014)
  • Author(s): 山村研一
  • Organizer: 日本人類遺伝学会第59回大会
  • Place of Presentation: タワーホール船堀(東京)
  • Year and Date: 2014-11-19 – 2014-11-22
  • Invited
• [Presentation] NPD926, a small molecule inducer of reactive oxygen species, kills cancer cells via glutathione depletion (2014)
  • Author(s): 河村達郎、近藤恭光、室井誠、川谷誠、長田裕之
  • Organizer: 26th EORTC-NCI-AACR Symposium on Molecular Targets & Cancer Therapeutics
  • Place of Presentation: Barcelona, Spain
  • Year and Date: 2014-11-19
• [Presentation] Human T-Lymphotropic Virus Type 1 Biomarkers in Patients with Rheumatoid Arthritis (2014)
  • Author(s): Okayama A, Iwanaga M, Sagara Y, Hidaka T, Umekita K, Nakano K, Watanabe T, Yamano Y, Horai Y, Nakamura H, Kawakami A
  • Organizer: ACR/ARHP Annual Meeting
  • Place of Presentation: Boston, U.S.A.
  • Year and Date: 2014-11-18
• [Presentation] Cold transport of mouse epididymides for distributing and archiving genetically engineered mice (2014)
  • Author(s): Takeo, T., Yoshimoto, H., Nakao, S., Ishizuka, Y., Horikoshi, Y., Takeuji, S., Hirose, Y., Mukunoki, A., Fukumoto, K., Kondo, T., Haruguchi, Y., Takeshita, Y., Nakamuta, Y., Tsuchiyama, S., Takahashi, F., Iwamoto, M., Shimizu, N., Li, M., Lloyd, K. and Nakagata, N.
  • Organizer: 第8回次世代を担う若手医療薬科学シンポジウム
  • Place of Presentation: 熊本大学薬学部(熊本県・熊本市)
  • Year and Date: 2014-11-15 – 2014-11-16
• [Presentation] Application of cold-storage of mouse sperm for shipping genetically engineered mice (2014)
  • Author(s): Takeuji, S., Yoshimoto, H., Nakao, S., Horikoshi, Y., Hirose, Y., Mukunoki, A., Shirakado, K., Takemoto, K., Takeo, T. and Nakagata, N.
  • Organizer: 第8回次世代を担う若手医療薬科学シンポジウム
  • Place of Presentation: 熊本大学薬学部(熊本県・熊本市)
  • Year and Date: 2014-11-15 – 2014-11-16
  • Invited
• [Presentation] 短時間睡眠における骨量低下リスクおよび自律神経活動 (2014)
  • Author(s): 栗山長門, 尾崎悦子, 松井大輔, 渡邊能行
  • Organizer: 第54回近畿産業衛生学会
  • Place of Presentation: 近畿大学東大阪キャンパス(大阪府・東大阪市)
  • Year and Date: 2014-11-15
• [Presentation] ATL発症機構の解析に基づく発症予防・新規治療法の探索 (2014)
  • Author(s): 渡邉俊樹
  • Organizer: 第13回さいたま血液勉強会、大日本住友製薬(株)主催
  • Place of Presentation: 大日本住友製薬(株)埼玉支店(埼玉県・さいたま市)
  • Year and Date: 2014-11-14
  • Invited
• [Presentation] Association between Fusobacterium expression and molecular feature using 391 Japanese patients with colorectal cancer (2014)
  • Author(s): 能正勝彦
  • Organizer: The 8th International Conference of the International Society of Gastroenterological Carcinogenesis
  • Place of Presentation: ホテル日航福岡(福岡県・福岡市)
  • Year and Date: 2014-11-14
• [Presentation] Characterization of Serine/Threonine phosphatase LAPP1 as a diagnostic and therapeutic target for lung cancer (2014)
  • Author(s): Daigo Y, Nakamura Y
  • Organizer: The 11th International Conference on Protein Phosphatase
  • Place of Presentation: 東北大学医学部艮陵会館(宮城県・仙台市)
  • Year and Date: 2014-11-13
• [Presentation] 大腸癌におけるmicroRNA-31とBRAF遺伝子変異や予後との関連 (2014)
  • Author(s): 五十嵐央祥
  • Organizer: 第25回消化器癌発生学会総会
  • Place of Presentation: ホテル日航福岡(福岡県・福岡市)
  • Year and Date: 2014-11-13
• [Presentation] HSP90阻害薬投与により変動するATL遺伝子群の探索 (2014)
  • Author(s): 池辺詠美, 緒方正男, 塚本善之, 手塚健太, Nichole Fife, 松本昂, 末岡栄三郎, 堀光雄, 長谷川寛雄, 森下和広, 田中勇悦, 藤澤順一, 守山正胤, 西園晃, 伊波英克
  • Organizer: 第62回日本ウイルス学会学術集会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-11-11
• [Presentation] HTLV-1gp46、OX40およびCD25を標的としたモノクローナル抗体によるHTLV-1感染細胞の制御 (2014)
  • Author(s): 高橋良明, 清水衡, 呂城拓也, 田中礼子, 國廣真里枝, 藤猪英樹, 田中勇悦
  • Organizer: 第62回日本ウイルス学会学術集会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-11-11
• [Presentation] HTLV-1 Tax抗原はT細胞表面にCD83を誘導する : Tax陽性細胞のlive cell sorting (2014)
  • Author(s): 藤猪英樹, 高橋良明, 田中礼子, 福島卓也, 友寄毅昭, 水口真理子, 中村正孝, 田中勇悦
  • Organizer: 第62回日本ウイルス学会学術集会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-11-11
• [Presentation] HTLV-1Env発現ウイルス産生細胞におけるHTLV-1受容体GLUT1の制御機構の解析 (2014)
  • Author(s): 前田洋助, 寺沢広美, 光浦智将, 中島詩織, 門出和精, 田中勇悦, 遊佐敬介, 原田信志
  • Organizer: 第62回日本ウイルス学会学術集会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-11-11
• [Presentation] Heat-ShockによるHTLV-1 Taxおよびgp46タンパクの発現増強と感染促進 (2014)
  • Author(s): 國廣真里枝, 藤猪英樹, 西連寺剛, 高橋良明, 田中礼子, 田中勇悦
  • Organizer: 第62回日本ウイルス学会学術集会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-11-11
• [Presentation] HTLV-1 PVLとHLA Class Ⅰ結合peptideの乖離時間との関連 (2014)
  • Author(s): 相良康子、井上由紀子、守田麻衣子、後藤信代、岩永正子、矢持忠徳、渡邉俊樹、浜口功、相良康弘、清川博之
  • Organizer: 第62回日本ウイルス学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-11-11
• [Presentation] The roles of acquired and innate immunity in HTLV1-infgection : Implacation for therapy and pathogenesis (2014)
  • Author(s): Mari Kannagi, Atsuhiko Hasegawa, Shuichi Kinpara, Youko Suehiro.
  • Organizer: 第62回日本ウイルス学会学術集会シンポジウム
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-11-10 – 2014-11-12
• [Presentation] HTLV-1 bZIP factorが惹起する炎症におけるIFNγの役割 (2014)
  • Author(s): 三田上侑生、安永純一朗、大島孝一、松岡雅雄
  • Organizer: 第62回日本ウイルス学会学術集会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-11-10 – 2014-11-12
• [Presentation] Anti-CCR4抗体はTregと感染細胞を同時に標的にする事で、STLV-1自然感染ニホンザルでのウイルス特異的免疫反応を活性化させる (2014)
  • Author(s): 菅田謙治、安永純一朗、三浦未知、明里宏文、小柳義夫、小原道法、松岡雅雄
  • Organizer: 第62回日本ウイルス学会学術集会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-11-10 – 2014-11-12
• [Presentation] 集団栄養調査における食事記録から算出した栄養摂取量の3日分と1日分の妥当性研究 (2014)
  • Author(s): 尾﨑悦子、弘田真央、瀬古千佳子、阪田亜実、加藤里佳、鍋島加名栄、宮谷史太郎、松井大輔、渡邉功、栗山長門、渡邊能行
  • Organizer: 第73回日本公衆衛生学会
  • Place of Presentation: 宇都宮東武グランドホテル(栃木県・宇都宮市)
  • Year and Date: 2014-11-07
• [Presentation] 唾液ストレスマーカーと口腔内状態との関連に関する検討 (2014)
  • Author(s): 松井大輔、渡邉功、宮谷史太郎、尾﨑悦子、弘田真央、瀬古千佳子、阪田亜実、栗山長門、渡邊能行
  • Organizer: 第73回日本公衆衛生学会
  • Place of Presentation: 宇都宮東武グランドホテル(栃木県・宇都宮市)
  • Year and Date: 2014-11-06
• [Presentation] Molecular mechanisms of leukemogenesis of adult T-cell leukemia (ATL) caused by HTLV-1 (2014)
  • Author(s): Watanabe T.
  • Organizer: 2d IARI Symposium
  • Place of Presentation: Lyon, France
  • Year and Date: 2014-11-03
• [Presentation] CD30 expressing cells in HTLV-1 carriers reveal abnormal nuclear morphology resembling flower cells (2014)
  • Author(s): Nakashima M, Yamochi T, Higashihara M, Watanabe T, Horie R
  • Organizer: 第76回日本血液学会学術集会
  • Place of Presentation: 大阪国際会議場(大阪府・大阪市)
  • Year and Date: 2014-11-01
• [Presentation] 全国医療機関における成人T細胞白血病・リンパ腫(ATL)患者の実態調査 2010年～2011年 (2014)
  • Author(s): 野坂生郷、岩永正子、石澤賢一、石田陽治、内丸薫、石塚賢治、天野正宏、石田高司、今泉芳孝、鵜池直邦、宇都宮與、大島孝一、河井一浩、田中淳司、戸倉新樹、飛内賢正、渡邉俊樹、塚崎邦弘
  • Organizer: 第76回日本血液学会学術集会
  • Place of Presentation: 大阪国際会議場(大阪府・大阪市)
  • Year and Date: 2014-11-01
• [Presentation] Tumor-specific gene expression leads to p38 and Hedgehog signaling activation in adult T cell leukemia (2014)
  • Author(s): Yamagishi M, Takahashi R, Sakai N, Fujikawa D, Nakagawa S, Yamochi T, Yamochi T, Nakano K, Uchimaru K, Utsunomiya A, Watanabe T
  • Organizer: 第76回日本血液学会学術集会
  • Place of Presentation: 大阪国際会議場(大阪府・大阪市)
  • Year and Date: 2014-11-01
• [Presentation] Distinct patterns of RHOA mutations in Adult T-Cell Leukemia/Lymphoma and peripheral T-Cell lymphomas (2014)
  • Author(s): Nagata Y, Enami T, Sakata-Yanagimoto M, Kataoka K, Kitanaka A, Sato A, Shiraishi Y, Chiba K, Tanaka H, Shiozawa Y, Yoshizato T, Kon A, Yoshida K, Sanada M, Ishiyama K, Miyawaki S, Ishii R, Nureki O, Miyano S, Shimoda K, Watanabe T, Chiba S, Ogawa S
  • Organizer: 第76回日本血液学会学術集会
  • Place of Presentation: 大阪国際会議場(大阪府・大阪市)
  • Year and Date: 2014-11-01
• [Presentation] Landscape of genetic alterations in adult T-cell leukemia/lymphoma (2014)
  • Author(s): Kataoka K, Nagata Y, Kitanaka A, Sato-Otsubo A, Totoki Y, Yasunaga J, Sanada M, Shiraishi Y, Chiba K, Tanaka H, Suzuki H, Sato Y, Shiozawa Y, Yoshizato T, Kon A, Yoshida K, Munakata W, Nakamura H, Hama N, Shide K, Kubuki Y, Hidaka T, Kameda T, Ishiyama K, Miyawaki S, Ishii R, Nureki 0, Nagae G, Aburatani H, Miyano S, Watanabe T, Matsuoka M, Shibata T, Shimoda K, Ogawa S
  • Organizer: 第76回日本血液学会学術集会
  • Place of Presentation: 大阪国際会議場(大阪府・大阪市)
  • Year and Date: 2014-11-01
• [Presentation] Dissecting cancer biology by studying induced pluripotency (2014)
  • Author(s): Yamada Y.
  • Organizer: Nature Conference, Nuclear Reprogramming and the Cancer Genome2014
  • Place of Presentation: Guangzhou, China
  • Year and Date: 2014-10-31 – 2014-11-02
  • Invited
• [Presentation] 睡眠者における安静および起立負荷時の心拍変動と骨量減少の関連 (2014)
  • Author(s): 栗山長門、鍋島加名栄、岩佐弘一
  • Organizer: 第67回日本自律神経学会総会
  • Place of Presentation: ラフレ埼玉(埼玉県・さいたま市)
  • Year and Date: 2014-10-31
• [Presentation] Suppressive effect of the farnesyltransferase inhibitor for aberrant crypt foci as a precursor of colorectal cancer (2014)
  • Author(s): Kimura T, Muguruma N, Takayama T.
  • Organizer: 第56回日本消化器病学会大会(JDDW2014)
  • Place of Presentation: 神戸国際会議場(兵庫県・神戸市)
  • Year and Date: 2014-10-25
• [Presentation] 60代女性における橈骨皮質骨および橈骨海綿骨骨密度の脆弱要因の検討 (2014)
  • Author(s): 尾﨑悦子、栗山長門、松井大輔、渡邉功、稲葉雅章、三島誉史、水野成人、弘田真央、米田勇太郎、渡邊能行
  • Organizer: 第16回日本骨粗鬆症学会
  • Place of Presentation: 京王プラザホテル(東京)
  • Year and Date: 2014-10-24
• [Presentation] 短時間睡眠者における骨量低下リスクおよび自律神経活動に関する横断的検討 (2014)
  • Author(s): 栗山長門、尾﨑悦子、稲葉雅章、堀井基行、水野成人、黒川正夫、岩佐弘一、松井大輔、米田勇太郎、渡邊能行
  • Organizer: 第16回日本骨粗鬆症学会
  • Place of Presentation: 京王プラザホテル(東京)
  • Year and Date: 2014-10-23
• [Presentation] Cryopreservation of mouse sperm (2014)
  • Author(s): Nakagata, N.
  • Organizer: AMMRA-AMPC STUDENT WORKSHOP
  • Place of Presentation: Canberra, Australia
  • Year and Date: 2014-10-22 – 2014-10-23
  • Invited
• [Presentation] Do you know how to maintain genetic quality of outbred colonies? (2014)
  • Author(s): Katoh H
  • Organizer: 65th AALAS National Meeting
  • Place of Presentation: San Antonio Convention Center, TX, U.S.A.
  • Year and Date: 2014-10-19 – 2014-10-23
  • Invited
• [Presentation] セリン・スレオニンフォスファターゼLAPP1の肺発がんにおける機能解析と診断・治療への応用 (2014)
  • Author(s): 醍醐弥太郎、中村祐輔
  • Organizer: 第87回日本生化学会大会シンポジウム
  • Place of Presentation: 国立京都国際会館・グランドプリンスホテル京都(京都府・京都市)
  • Year and Date: 2014-10-18
• [Presentation] Longitudinal relationships of perceived stress and coping strategies with C-reactive protein in middle-aged and older men and women (2014)
  • Author(s): Shimanoe C, Hara M, Nishida Y, Nanri H, Otsuka Y, Horita M, Yasukata J, Miyoshi N, Yamada Y, Higaki Y, Shinchi K, Tanaka K
  • Organizer: WPA Section on Epidemiology and Public Health Meeting
  • Place of Presentation: 奈良県新公会堂(奈良県・奈良市)
  • Year and Date: 2014-10-16 – 2014-10-18
• [Presentation] 酸素と鉄の親和性 : 鉄過剰と発がん (2014)
  • Author(s): 豊國伸哉
  • Organizer: レドックスシンポジウム : 酸素生物学の誕生
  • Place of Presentation: 名古屋大学ES総合館ESホール(愛知県・名古屋市)
  • Year and Date: 2014-10-11
  • Invited
• [Presentation] ATL発症機構の解析に基づく発症予防法と治療法の開発 (2014)
  • Author(s): 渡邉俊樹
  • Organizer: ATL学術集会、協和発酵キリン(株)主催
  • Place of Presentation: 盛岡グランドホテル(岩手県・盛岡市)
  • Year and Date: 2014-10-09
  • Invited
• [Presentation] Line up new enzyme-linked immune-sorbent assay (ELISA) kits for quantitation of HTLV-1(gp46, p24, Tax), Tax-related antigens (OX40, OX40L, CD25) and HIV-1 p24 (2014)
  • Author(s): Tanaka R, Kodama A, Tanaka Y.
  • Organizer: 4th World Congress on Virology
  • Place of Presentation: San Antonio, U.S.A.
  • Year and Date: 2014-10-07
• [Presentation] Control of infection with human T cell leukemia virus type-1 (HTLV-1) by humanized neutralizing anti-HTLV-1 gp46 antibody (2014)
  • Author(s): Tanaka Y
  • Organizer: 4th World Congress on Virology
  • Place of Presentation: San Antonio, U.S.A.
  • Year and Date: 2014-10-07
• [Presentation] Isolation and target identification of pyrrolizilactone (2014)
  • Author(s): 長田裕之
  • Organizer: 2014 Osong International Symposium
  • Place of Presentation: Osong, Korea
  • Year and Date: 2014-10-07
• [Presentation] Platinum TALENによる効率的な遺伝子改変マウスの作製 (2014)
  • Author(s): 中川佳子、佐久間哲史、中潟直己、大村谷昌樹、山本卓
  • Organizer: 第4回ゲノム編集研究会
  • Place of Presentation: 広島国際会議場(広島県・広島市)
  • Year and Date: 2014-10-06
• [Presentation] 老化誘導型核酸医薬の開発 (2014)
  • Author(s): 田原栄俊
  • Organizer: 新適塾「未来創薬への誘い」第28回会合
  • Place of Presentation: 千里ライフサイエンスセンター(大阪府・豊中市)
  • Year and Date: 2014-10-06
  • Invited
• [Presentation] HTLV-I感染細胞および上皮系腫瘍細胞においてユビキチン化修飾酵素A20はcaspase-8抑制因子として機能する (2014)
  • Author(s): 斉藤愛記、持田佳奈子、鶴山惠理、市川裕菜、大友悠太郎、掛谷綾香、深澤麻純、宇野雅哉、徳永文稔、宇都宮與、渡邉俊樹、山岡昇司
  • Organizer: 新学術領域研究「修飾シグナル病」若手ワークショップ
  • Place of Presentation: ホテルあかね(神奈川県・足柄下郡湯河原町)
  • Year and Date: 2014-09-30 – 2014-10-02
• [Presentation] テロメア検査、マイクロRNA検査を用いた健康管理への活用 (2014)
  • Author(s): 田原栄俊
  • Organizer: 第24回日本医療薬学会年会シンポジウム
  • Place of Presentation: 名古屋国際会議場(愛知県・名古屋市)
  • Year and Date: 2014-09-28
  • Invited
• [Presentation] Exploration of sensitivity/resistance-related genes for docetaxel, cisplatin and 5-fluorouracil used for the TPF treatment of hypopharyngeal cancer (2014)
  • Author(s): Yumiko Shimamura, Hidetaka Eguchi, Satoru Wada, Mitsuhiko Nakahira, Yasushi Okazaki, Testuya Yoda, Reidar Grenman, Masashi Sugasawa, Masahiko Nishimyama
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-27
• [Presentation] EGFR expression and efficacy of anti-EGFR antibody in colorectal cancer (2014)
  • Author(s): Okada Y, Tanaka H, Taniguchi T, Takayama T
  • Organizer: The 73rd annual meeting of the Japanese Cancer Association
  • Place of Presentation: Yokohama, Japan
  • Year and Date: 2014-09-27
• [Presentation] MicroRNA-31-5p expression in relation to BRAF mutation, CIMP status and colorectal continuum in serrated pathway (2014)
  • Author(s): 能正勝彦
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-27
• [Presentation] Cancer initiating cekk of lung squamous cell carcinoma in mice might be cerived from the bronchiolar alveolar stem cell (2014)
  • Author(s): Yamano S, Wei M, Fujioka M, Wanibuchi H
  • Organizer: 39th EAMO Congress
  • Place of Presentation: Madrid, Spain
  • Year and Date: 2014-09-26 – 2014-09-30
• [Presentation] Des-g-carboxy prothrombin is produced by elevated transcription of prothrombin gene in hepatocellular carcinoma (2014)
  • Author(s): Taniguchi T, Kagemoto K, Tanaka H, Tanaka T, Tomonari T, Sannomiya K, Miyamoto H, Muguruma N, Takayama T.
  • Organizer: The 73rd annual meeting of the Japanese Cancer Association
  • Place of Presentation: Yokohama, Japan
  • Year and Date: 2014-09-26
• [Presentation] CE-TOFMS法を用いたATL細胞の小分子量メタボライトのプロファイリング (2014)
  • Author(s): 伊波英克, 池辺詠美, 紙健次郎, 長谷川寛雄, 田中勇悦, 森下和広, 堀光雄
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-26
• [Presentation] HTLV-I感染中和及びADCC活性を持つヒト化ラット由来単クロン抗体 (2014)
  • Author(s): 田中勇悦
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-26
• [Presentation] 成人T細胞白血病/リンパ腫と他の末梢性T細胞性腫瘍におけるRHOAの特徴的な変異分布と生物学的機能の解析 (2014)
  • Author(s): 永田安伸、榎並輝和、坂田(柳元)麻実子、片岡圭亮、北中明、佐藤亜以子、白石友一、眞田昌、宮野悟、下田和哉、渡邉俊樹、千葉滋、小川誠司
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-26
• [Presentation] 神奈川県立がんセンターにおけるがん関連試料の収集と提供 (2014)
  • Author(s): 宮城洋平, 今井浩三
  • Organizer: 第73回日本癌学会学術総会シンポジウム
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-26
• [Presentation] SPINK1ノックインマウスではオートファジー機能不全により慢性膵炎が惹起される (2014)
  • Author(s): 坂田和也, 大村谷昌樹, 荒木喜美, 高城克暢, 橋本大輔, 近本亮, 山村研一, 馬場秀夫
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] CHOP欠損による慢性炎症からの膵線維化進展 (2014)
  • Author(s): 高城克暢, 大村谷昌樹, 橋本大輔, 東孝暁, 坂本慶太, 坂田和也, 新田英利, 林洋光, 近本亮, 別府透, 荒木喜美, 山村研一, 馬場秀夫
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] TACC3を標的とした低分子化合物の開発と応用 (2014)
  • Author(s): 八尾良司、長田裕之、吉田稔、野田哲生
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] オルガノイドを用いたTACC3阻害による消化管腫瘍抑制機構の解析 (2014)
  • Author(s): 小柳潤、八尾良司、野田哲生
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] 哺乳動物細胞の低用量ストレス応答におけるヒストンシャペロンHIRAの機能解析 (2014)
  • Author(s): 長垣良和、中條萌絵子、樽本雄介、八尾良司、石川冬木
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] 消化管腫瘍形成におけるAPC1309の機能解析 (2014)
  • Author(s): 高野洋、八尾良司、野田哲生
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] 小脳髄芽腫の散発性マウスモデルを用いた腫瘍微小環境の解析 (2014)
  • Author(s): 柳沼克幸
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] Molecular basis underlying the multi-step process in spontaneous medulloblastoma development (2014)
  • Author(s): Sugitani Y., Yaginuma K., Noda T.
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] シンポジウム : ゲノム制御から見た環境発がん : 中皮腫発癌機構解明とその予防への挑戦 (2014)
  • Author(s): 豊國伸哉
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25 – 2014-09-27
  • Invited
• [Presentation] ハムスター化学発がんモデルを用いた1,2-dichloropropaneの発がん修飾作用の検討 (2014)
  • Author(s): 魏民、下村衣里、藤岡正喜、山野荘太郎、梯アンナ、石井真美、武下正憲、房赫、鰐渕英機
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] ヒトNASH肝細胞癌におけるプロテオーム解析を用いた分枝メカニズムの検討 (2014)
  • Author(s): 石井真美、梯アンナ、桑江優子、大澤政彦、魏民、鰐渕英機
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] gpt deltaラットを用いた2-AAFの肝発がん性および変異原性の包括的評価モデルの検討 (2014)
  • Author(s): 藤岡正喜、魏民、山野荘太郎、梯アンナ、石井真美、下村衣里、三島胡桃、房赫、鰐渕英機
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] ヒト肝細胞癌における新治療ターゲットの検索 : CNPY2及びCACHD1 (2014)
  • Author(s): 梯アンナ、石井真美、桑江優子、房赫、藤岡正喜、魏民、鰐渕英機
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] ピロリ菌CagA発現マウス胃粘膜における粘液細胞化生(SPEM)の誘導 (2014)
  • Author(s): 柳谷公平、藤井裕美子、神田浩明、畠山昌則
  • Organizer: 第73回日本癌学会総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] ビスフォスフォネートあるいは抗RANKL抗体で治療した骨巨細胞腫の組織学的検討 (2014)
  • Author(s): 神田浩明、元井紀子、杉浦善弥、谷沢泰介、松本誠一、町並陸生、石川雄一
  • Organizer: 第73回日本癌学会総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] FNCLCCシステムを用いた、組織型組織亜型レベルでの軟部肉腫の予後解析 (2014)
  • Author(s): 杉浦善弥、元井紀子、神田浩明、岡田絵里奈、牛嶋大、松浦正明、松本誠一、中山淳、町並陸生、石川雄一
  • Organizer: 第73回日本癌学会総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] Immune control of the retrovirus-induced adult T-cell leukemia : fighting with invisible enemy (2014)
  • Author(s): Kannagi M.
  • Organizer: 第73回日本癌学会総会シンポジウム
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] Involvement of PKR and anti-sense HTLV-1 transcripts in the constitutive activation of NF κ B in ATL cells (2014)
  • Author(s): Shuichi Kinpara, Yasunori Saitoh, Atsuhiko Hasegawa, Atae Utsunomiya, Masato Masuda, Yasushi Miyazaki, Masao Matsuoka, Masataka Nakamura, Shoji Yamaoka, Takao Masuda, Mari Kannagi.
  • Organizer: 第73回日本癌学会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] HTLV-1による発がん機構 (2014)
  • Author(s): 松岡雅雄
  • Organizer: 第73回日本癌学会学術総会 シンホジウム
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] HTLV-1 bZIP factor(HBZ)はRbタンパクと相互作用し、E2F-1/Rb経路を改変する (2014)
  • Author(s): 川月章弘、安永純一朗、松岡雅雄
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] 転写因子TCF1、LEF1はHTLV-1 Taxを阻害し末梢Tリンパ球への感染指向性に関与する (2014)
  • Author(s): 安永純一朗、松岡雅雄
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] Elucidation of transcriptional regulatory circuitry involved in the molecular pathogenesis of lung cancer (2014)
  • Author(s): Takahashi T
  • Organizer: 第73回日本癌学会学術総会シンポジウム
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] A pivotal role of CERS6 on the sphingolipid metabolic pathways and tumor metastasis in lung cancer (2014)
  • Author(s): Suzuki M, Murate T, Kyogashima M, Takahashi T
  • Organizer: 第73回日本癌学会学術総会シンポジウム
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] ラットモデルにおけるHTLV-1新規感染に対する抗HTLV-1gp46中和抗体ワクチンの効果 (2014)
  • Author(s): 村上悠二, 安藤聡美, 田中勇悦, 田中礼子, 増田貴夫, 神奈木真理, 長谷川温彦
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25
• [Presentation] ATL細胞におけるEZH2依存的エビジェネティック異常の包括的解析 (2014)
  • Author(s): 藤川大, 山岸誠, 中川翔太, 黒川直也, 副島あい, 石田尚臣, 田中勇悦, 中野和民, 渡邉俊樹
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25
• [Presentation] 「ATL発症の基盤となるゲノム・エピゲノム異常の解析」、シンポジウム : 16. ATL発がん機構と治療の新展開 (2014)
  • Author(s): 渡邉俊樹、山岸誠
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25
  • Invited
• [Presentation] 「成人T細胞白血病/リンパ腫におけるゲノム異常の網羅的解析」、シンポジウム : 16. ATL発がん機構と治療の新展開 (2014)
  • Author(s): 片岡圭亮、永田安伸、北中明、佐藤亜以子、十時康、安永純一朗、油谷浩幸、宮野悟、渡邉俊樹、松岡雅雄、柴田龍弘、下田和哉、小川誠司
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25
• [Presentation] ATL細胞におけるEZH2依存的エピジェネティック異常の包括的解析 (2014)
  • Author(s): 藤川大、山岸誠、中川翔太、黒川直也、副島あい、石田尚臣、田中勇悦、中野和民、渡邉俊樹
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25
• [Presentation] Putative ATL tumor initiating cellsの解析 (2014)
  • Author(s): 矢持忠徳、守田陽平、矢持淑子、Sanaz Firouzi、佐々木陽介、渡辺信和、内丸薫、宇都宮與、渡邉俊樹
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25
• [Presentation] A new high-throughput method to investigate the clonality of HTLV-1-infected cells based on provirus integration sites (2014)
  • Author(s): Sanaz Firouzi, Tadanori Yamochi, Yosvany Lopez, Yutaka Suzuki, Kenta Nakai, Sumio Sugano, Toshiki Watanabe
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25
• [Presentation] DNAメチル化解析による肝芽腫の新規予後予測マーカーの確立 (2014)
  • Author(s): 本多昌平
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-09-25
• [Presentation] 生活習慣病の遺伝子環境交互作用の解明を目指して : 日本多施設共同コーホート研究-佐賀地区- (2014)
  • Author(s): 田中恵太郎
  • Organizer: 第17回日本運動疫学会学術総会
  • Place of Presentation: 長崎大学文教キャンパス(長崎県・長崎市)
  • Year and Date: 2014-09-18
• [Presentation] Optical Molecular Imaging and Assessment of Therapeutic Response of Colorectal Cancer Targeting Epidermal Growth Factor Receptor (2014)
  • Author(s): Muguruma N, Miyamoto Y, Fujimoto S, Fujino Y, Okada Y, Kitamura S, Kimura T, Okamoto K, Miyamoto H, Takayama T.
  • Organizer: The world Molecular Imaging Congress
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2014-09-17 – 2014-09-20
• [Presentation] シンポジウム1「鉄と腫瘍」過剰鉄による発がん機構の解明からその予防へ (2014)
  • Author(s): 豊國伸哉、蒋麗、岡崎泰昌、赤塚慎也
  • Organizer: 第38回日本鉄バイオサイエンス学会学術集会
  • Place of Presentation: 仙台国際センター(宮城県・仙台市)
  • Year and Date: 2014-09-06 – 2014-09-07
  • Invited
• [Presentation] 成人T細胞白血病ウイルス(HTLV-I)の感染予防ワクチン : ヒト化感染中和抗体 (2014)
  • Author(s): 田中勇悦, 清水衡, 高橋良明, 藤猪英樹, 田中礼子
  • Organizer: 第51回日本ウイルス学会九州支部総会
  • Place of Presentation: 城山観光ホテル(鹿児島県・鹿児島市)
  • Year and Date: 2014-09-06
• [Presentation] CTLエピトープペプチドパルス樹状細胞によるウイルス特異的T細胞の誘導および感染細胞の制御 (2014)
  • Author(s): 安藤聡美、長谷川温彦、村上悠二、神奈木真理
  • Organizer: 血液疾患免疫療法学会
  • Place of Presentation: 京都大学芝蘭会館(京都府・京都市)
  • Year and Date: 2014-09-05 – 2014-09-06
• [Presentation] HTLV-1 Tax抗原はT細胞表面にCD83を誘導する : Tax陽性細胞のlive cell sorting (2014)
  • Author(s): 藤猪英樹, 高橋良明, 田中礼子, 福島卓也, 友寄毅昭, 水口真理子, 中村正孝, 田中勇悦
  • Organizer: 第51回日本ウイルス学会九州支部総会
  • Place of Presentation: 城山観光ホテル(鹿児島県・鹿児島市)
  • Year and Date: 2014-09-05
• [Presentation] レクチンアレイによるATLバイオマーカーの探索 (2014)
  • Author(s): 池辺詠美, 緒方正男, 手塚健太, ファイフ ニコール, 松本昂, 末岡栄三郎, 堀光雄, 長谷川寛雄, 森下和広, 田中勇悦, 児玉大介, 出雲周二, 藤澤順一, 西園晃, 伊波英克
  • Organizer: 第51回日本ウイルス学会九州支部総会
  • Place of Presentation: 城山観光ホテル(鹿児島県・鹿児島市)
  • Year and Date: 2014-09-05
• [Presentation] 腎発がんモデルを用いた発がん機構の解明及び転移モデルへの応用 (2014)
  • Author(s): 山野荘太郎、三島胡桃、藤岡正喜、魏民、鰐渕英機
  • Organizer: 平成26年度がん若手研究者ワークショップ
  • Place of Presentation: 蓼科グランドホテル滝の湯(長野県・茅野市)
  • Year and Date: 2014-09-03 – 2014-09-06
• [Presentation] 細胞老化を誘導するmicroRNAの網羅的スクリーニング, High-content screening of senescence-associated microRNAs (2014)
  • Author(s): 山本佑樹、塩谷文章、嶋本顕、田原栄俊
  • Organizer: 平成26年度がん若手研究者ワークショップ
  • Place of Presentation: 蓼科グランドホテル滝の湯(長野県・茅野市)
  • Year and Date: 2014-09-03 – 2014-09-06
• [Presentation] ハムスターBOP二段階胆膵管発がんモデルを用いた1,2-dichloropropaneの発がん修飾作用の検討 (2014)
  • Author(s): 下村衣里、魏民、藤岡正喜、山野荘太郎、梯アンナ、三島胡桃、鰐渕英機
  • Organizer: 第29回発癌病理研究会
  • Place of Presentation: スパリゾートハワイアンズコンベンションセンター(福島県・いわき市)
  • Year and Date: 2014-09-01 – 2014-09-03
• [Presentation] EHEN誘発ラット腎発がんにおける発がん機序の解明PI3K/Akt/mTOR signaling pathway及びNADPH oxidaseの役割 (2014)
  • Author(s): 三島胡桃、山野荘太郎、藤岡正喜、魏民、下村衣里、鰐渕英機
  • Organizer: 第29回発癌病理研究会
  • Place of Presentation: スパリゾートハワイアンズコンベンションセンター(福島県・いわき市)
  • Year and Date: 2014-09-01 – 2014-09-03
• [Presentation] Connective tissue growth factor and beta-catenin consitute an autocrinne loop for activation in rat sarcomatoid mesothelioma (2014)
  • Author(s): Jiang L and Toyouni S
  • Organizer: 第6回日本CCNファミリー研究会 シンポジウム : CCNファミリー研究のフロンティア
  • Place of Presentation: 岡山大学(岡山県・岡山市)
  • Year and Date: 2014-08-30
  • Invited
• [Presentation] 細胞老化における細胞外小胞エクソソーム分泌の生物学的意義の探索, The analysis of biological significance of exosomes in replicative senescence (2014)
  • Author(s): 岡田恵、宗岡美紗、岡本沙矢香、二瀬由宇、塩谷文章、嶋本顕、田原栄俊
  • Organizer: 第6回日本RNAi研究会
  • Place of Presentation: グランドプリンスホテル広島(広島県・広島市)
  • Year and Date: 2014-08-29
• [Presentation] Direct detection of extracellular vesicles and exRNA, Direct detection of extracellular vesicles and exRNA (2014)
  • Author(s): 田原栄俊
  • Organizer: 第1回日本細胞外小胞学会
  • Place of Presentation: グランドプリンスホテル広島(広島県・広島市)
  • Year and Date: 2014-08-28
  • Invited
• [Presentation] 老化を調節するmicroRNAによる膵臓がん抑制機構の解析, Functional analysis of senescence-associated miRNA suppresses pancreatic cancer (2014)
  • Author(s): 福永早央里、塩谷文、嶋本顕、田原栄俊
  • Organizer: 第6回日本RNAi研究会
  • Place of Presentation: グランドプリンスホテル広島(広島県・広島市)
  • Year and Date: 2014-08-28
• [Presentation] 細胞老化を誘導するmicroRNAの網羅的スクリーニング, High-content screening of senescence-associated microRNAs (2014)
  • Author(s): 山本佑樹、塩谷文章、嶋本顕、田原栄俊
  • Organizer: 第6回日本RNAi研究会
  • Place of Presentation: グランドプリンスホテル広島(広島県・広島市)
  • Year and Date: 2014-08-28
• [Presentation] スペクトル型フローサイトメーターSP6800によるエクソソームの一粒子測定, Direct Detection of Exosome by SP6800 Spectral Analyzer (2014)
  • Author(s): 品末聡也、岡田恵、宗岡美紗、植田俊樹、佐古直紀、新田尚、田原栄俊
  • Organizer: 第6回日本RNAi研究会
  • Place of Presentation: グランドプリンスホテル広島(広島県・広島市)
  • Year and Date: 2014-08-28
• [Presentation] アルツハイマー患者における血漿中マイクロRNAの解析と診断への応用, Analysis of plasma miRNAs in patients with Alzheimer's disease as applied to the diagnosis (2014)
  • Author(s): 二瀬由宇、岡田沙矢香、竹田育子、高橋哲也、松本昌泰、田原栄俊
  • Organizer: 第6回日本RNAi研究会
  • Place of Presentation: グランドプリンスホテル広島(広島県・広島市)
  • Year and Date: 2014-08-28
• [Presentation] 抗HTLV-1gp46中和ADCC抗体によるin vivo HTLV-1感染制御 (2014)
  • Author(s): 藤猪英樹, 清水衡, 高橋良明, 田中礼子, 田中勇悦
  • Organizer: 第1回日本HTLV-1学会学術集会
  • Place of Presentation: 東京大学医科学研究所1号館講堂(東京)
  • Year and Date: 2014-08-24
• [Presentation] ATL細胞におけるEZH2依存的エピジェネティック異常の包括的解析 (2014)
  • Author(s): 藤川大, 山岸誠, 黒川直也, 副島あい, 中川翔太, 石田尚臣, 田中勇悦, 中野和民, 渡邉俊樹
  • Organizer: 第1回日本HTLV-1学会学術集会
  • Place of Presentation: 東京大学医科学研究所1号館講堂(東京)
  • Year and Date: 2014-08-24
• [Presentation] HTLV-1によるTh1-like CD4+CCR4+T細胞の発生機構の解析 (2014)
  • Author(s): 新谷奈津美, 佐藤知雄, 安藤仁, 外丸詩野, Ariella Coler-Reilly, 八木下尚子, 山内淳司, 長谷川温彦, 神奈木真理, 田中勇悦, 宇都宮與, 山野嘉久
  • Organizer: 第1回日本HTLV-1学会学術集会
  • Place of Presentation: 東京大学医科学研究所1号館講堂(東京)
  • Year and Date: 2014-08-24
• [Presentation] ATL細胞内NF-κB経路活性化に対するPKR分子とHTLV-I LTR領域由来転写産物の寄与 (2014)
  • Author(s): 金原秀一、斉藤愛記、長谷川温彦、宇都宮與、増田昌人、宮崎泰司、松岡雅雄、中村正孝、山岡昇司、増田貴夫、神奈木真理
  • Organizer: 2014HTLV-1学会
  • Place of Presentation: 東京大学医科学研究所(東京)
  • Year and Date: 2014-08-23 – 2014-08-24
• [Presentation] HTLV-1感染細胞における自然免疫応答の検討 (2014)
  • Author(s): 伊藤さやか、金原秀一、金井秀美、野上開、Sawada Leila, 永野佳子、長谷川温彦、神奈木真理
  • Organizer: 2014HTLV-1学会
  • Place of Presentation: 東京大学医科学研究所(東京)
  • Year and Date: 2014-08-23 – 2014-08-24
• [Presentation] HTLV-1感染細胞におけるA20はユビキチン化修飾酵素活性非依存的に細胞生存を支える (2014)
  • Author(s): 齋藤愛記、持田佳奈子、鶴山惠理、徳永文稔、山岡昇司
  • Organizer: 第1回日本HTLV-1学会学術集会
  • Place of Presentation: 東京大学医科学研究所1号館講堂(東京)
  • Year and Date: 2014-08-23
• [Presentation] 単鎖抗体(scFv)を用いたHTLV-1感染細胞特異的miRNA輸送システムの構築 (2014)
  • Author(s): 西田亜季, 長門石曉, 中野和民, 山岸誠, 矢持忠徳, 田中勇悦, 津本浩平, 渡邉俊樹
  • Organizer: 第1回日本HTLV-1学会学術集会
  • Place of Presentation: 東京大学医科学研究所1号館講堂(東京)
  • Year and Date: 2014-08-23
• [Presentation] 細胞外に排出するメタボライトの定量によるATLバイオマーカーの探索 (2014)
  • Author(s): 池辺詠美, 緒方正男, 手塚健太, ファイフ ニコール, 松本昂, 末岡栄三郎, 堀光雄, 長谷川寛雄, 森下和広, 田中勇悦, 藤澤順一, 西園晃, 伊波英克
  • Organizer: 第1回日本HTLV-1学会学術集会
  • Place of Presentation: 東京大学医科学研究所1号館講堂(東京)
  • Year and Date: 2014-08-23
• [Presentation] HTLV-1感染者の新鮮及び培養PBMCのTax抗原発現 : Tax抗原簡便フローサイトメトリー(Tax-FCM)を用いた解析 (2014)
  • Author(s): 田中勇悦, 高橋良明, 藤猪英樹, 宮城拓也, 田中礼子, 友寄毅昭, 福島卓也
  • Organizer: 第1回日本HTLV-1学会学術集会
  • Place of Presentation: 東京大学医科学研究所1号館講堂(東京)
  • Year and Date: 2014-08-23
• [Presentation] ATL細胞におけるCADM1高発現に必須なNF-κB活性化には、新規制御因子p47の発現低下が関係する (2014)
  • Author(s): 西片一朗, 市川朝永, 中畑新吾, 藤井雅寛, 伊波英克, 白神俊幸, 田中勇悦, 井上純一郎, 森下和広
  • Organizer: 第1回日本HTLV-1学会学術集会
  • Place of Presentation: 東京大学医科学研究所1号館講堂(東京)
  • Year and Date: 2014-08-23
• [Presentation] A new high-throughput method to investigate the clonality of HTLV-1-infected cells based on provirus integration sites (2014)
  • Author(s): Sanaz Firouzi, Tadanori Yamochi, Yosvany López, Yutaka Suzuki, Kenta Nakai, Sumio Sugano, Toshiki Watanabe
  • Organizer: 第1回日本HTLV-1学会学術集会
  • Place of Presentation: 東京大学医科学研究所1号館講堂(東京)
  • Year and Date: 2014-08-23
• [Presentation] CD30はHTLV-1キャリアにおける異常リンパ球に発現し、核の形態変化に関与する (2014)
  • Author(s): 中島誠、矢持忠徳、東原正明、渡邉俊樹、堀江良一
  • Organizer: 第1回日本HTLV-1学会学術集会
  • Place of Presentation: 東京大学医科学研究所1号館講堂(東京)
  • Year and Date: 2014-08-23
• [Presentation] 血中可溶型CADM1/TSLC1測定によるATL診断法の開発 (2014)
  • Author(s): 中武彩子、小林行治、中畑新吾、西片一朗、岩永正子、相良康子、北中明、天野正宏、前田宏一、末岡栄三朗、瀬戸山充、岡山昭彦、宇都宮與、下田和哉、渡邉俊樹、森下和広
  • Organizer: 第1回日本HTLV-1学会学術集会
  • Place of Presentation: 東京大学医科学研究所1号館講堂(東京)
  • Year and Date: 2014-08-23
• [Presentation] HTLV-1キャリアの可溶性CD30血中濃度と成人T細胞白血病発症リスク : 症例対照研究 (2014)
  • Author(s): 武本重毅、岩永正子、ポルンクナラティオン、相良康子、鵜澤耕治、守田和樹、渡邉俊樹
  • Organizer: 第1回日本HTLV-1学会学術集会
  • Place of Presentation: 東京大学医科学研究所1号館講堂(東京)
  • Year and Date: 2014-08-23
• [Presentation] 宿主F-boxタンパク質FBXL11はTaxとHBZのユビキチン化を誘導し機能を活性化する (2014)
  • Author(s): 安永純一朗、園直希、馬広勇、萩谷啓太、松岡雅雄
  • Organizer: 第1回日本HTLV-1学会学術集会
  • Place of Presentation: 東京大学医科学研究所1号館講堂(東京)
  • Year and Date: 2014-08-22 – 2014-08-24
• [Presentation] HTLVー1モデルマウスであるHBZ-Tgマウスにおける癌幹細胞の同定と機能解析 (2014)
  • Author(s): 栗林和華子、水上拓郎、滝澤和也、倉光球、浅田善久、岩間厚志、松岡雅雄、濵口功
  • Organizer: 第1回日本HTLV-1学会学術集会
  • Place of Presentation: 東京大学医科学研究所1号館講堂(東京)
  • Year and Date: 2014-08-22 – 2014-08-24
• [Presentation] HTLV-1 bZIP factorが惹起する炎症にはIFNγが重要な役割を果たす (2014)
  • Author(s): 三田上侑生、安永純一朗、大島孝一、松岡雅雄
  • Organizer: 第1回日本HTLV-1学会学術集会
  • Place of Presentation: 東京大学医科学研究所1号館講堂(東京)
  • Year and Date: 2014-08-22 – 2014-08-24
• [Presentation] TCF1/LEF1 are T-cell natural HTLV-1 Tax antagonists that restrict viralexpansion in thymus (2014)
  • Author(s): Guangyong Ma, Jun-ichiro Yasunaga, Masao Matsuoka
  • Organizer: The 1st Annual Meeting of the Japanese Society of HTLV-1and Associated Deceases
  • Place of Presentation: 東京大学医科学研究所1号館講堂(東京)
  • Year and Date: 2014-08-22 – 2014-08-24
• [Presentation] 京都府民における朝食の主食摂取別栄養摂取量および料理摂取頻度の検討 (2014)
  • Author(s): 弘田真央、尾﨑悦子、瀬古千佳子、加藤里佳、駒井実香、東あかね
  • Organizer: 第61回日本栄養改善学会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-08-22
• [Presentation] Helicobacter Pylori感染者における慢性萎縮性胃炎と摂取栄養素量との関連に関する検討 (2014)
  • Author(s): 瀬古千佳子、弘田真央、加藤里佳、尾﨑悦子
  • Organizer: 第61回日本栄養改善学会
  • Place of Presentation: パシフィコ横浜(神奈川県・横浜市)
  • Year and Date: 2014-08-22
• [Presentation] 老化誘導型核酸医薬の開発に向けて (2014)
  • Author(s): 田原栄俊
  • Organizer: 「がん研究分野の特性等を踏まえた支援活動」公開シンポジウム
  • Place of Presentation: 学術総合センター(東京)
  • Year and Date: 2014-08-21
  • Invited
• [Presentation] Significant associations of abdominal obesity with LYPLAL1 polymorphism (rs4846567) among a general Japanese population : a cross-sectional study (2014)
  • Author(s): Takashi T, Morita E, Kawai S, Sasakabe T, Fukuda N, Sugimoto Y, Suma S, Mokuno J, Nakagawa H, Hishida A, Okada R, Naito M, Hamajima N, Wakai K
  • Organizer: The 20th IEA World Congress of Epidemiology
  • Place of Presentation: Anchorage, Alaska, U.S.A.
  • Year and Date: 2014-08-19
• [Presentation] Dysphagia and dietary intake of Japanese adults : the Shizuoka area in a Japanese multi-institutional collaborative cohort study (2014)
  • Author(s): Naito M, Wakai K, Kawai S, Nakagawa H, Tamura T, Suma S, Sugimoto Y, Fukuda N, Sasakbe T, Okada R, Morita E, Asai Y, Mori A, Hamajima N
  • Organizer: The 20th IEA World Congress of Epidemiology
  • Place of Presentation: Anchorage, Alaska, U.S.A.
  • Year and Date: 2014-08-19
• [Presentation] The Correlation between Microbleeds And Cnm-positive Streptococcus Mutans : A Pilot Survey Study Based On Magnetic Resonance Imaging (2014)
  • Author(s): Nagato Kuriyama, Isao Watanabe, Fumitaro Miyatani, Daisuke Matsui, Etsuko Ozaki, Ryota Nomura, Kazuhiko Nakano and Yoshiyuki Watanabe
  • Organizer: The 20th IEA World Congress of Epidemiology
  • Place of Presentation: Anchorage, U.S.A.
  • Year and Date: 2014-08-17 – 2014-08-21
• [Presentation] Interaction between interleukin1-β gene polymorphism and cigarette smoking on HbA1c in a Japanese general population (2014)
  • Author(s): Nishida Y, Hara M, Nanri H, Nakamura K, Imaizumi T, Sakamoto T, Higaki Y, Taguchi N, Horita M, Shinchi K, Tanaka K
  • Organizer: 20th IEA World Congress of Epidemiology
  • Place of Presentation: Anchorage, U.S.A.
  • Year and Date: 2014-08-17 – 2014-08-21
• [Presentation] Perceived stress and coping strategies in relation to body mass index : cross-sectional study of 12,045 Japanese men and women (2014)
  • Author(s): Shimanoe C, Hara M, Nishida Y, Nanri H, Otsuka Y, Nakamura K, Higaki Y, Imaizumi T, Taguchi N, Sakamoto T, Horita M, Shinchi K, Tanaka K
  • Organizer: 20th IEA World Congress of Epidemiology
  • Place of Presentation: Anchorage, U.S.A.
  • Year and Date: 2014-08-17 – 2014-08-21
• [Presentation] The association of alcohol intake with serum lipid profile and its modification by ADH1B and ALDH2 polymorphisms : J-MICC Study (2014)
  • Author(s): Sasakabe T, Guang Y, Naito M, Morita E, Kawai S, Okada R, Tamura T, Nakagawa H, Suma S, Fukuda N, Sugimoto Y, Wakai K, Hamajima N
  • Organizer: The 20th IEA World Congress of Epidemiology
  • Place of Presentation: Anchorage, Alaska, U.S.A.
  • Year and Date: 2014-08-17
• [Presentation] Different functional modes of Brn factors contribute to generate diverse projection neurons and glial cells in neocortex (2014)
  • Author(s): Sugitani Y., Sugitani-Yoshida R., Nakai S., Ogawa M., Minowa O., Noda T.
  • Organizer: Gordon Research Conference, Neural Development 2014
  • Place of Presentation: Newport, U.S.A.
  • Year and Date: 2014-08-14
• [Presentation] Chemical biology for drug discovery and target identification (2014)
  • Author(s): 掛谷秀昭
  • Organizer: IUPAC2014 & 248th ACS National Meeting
  • Place of Presentation: San Francisco, U.S.A.
  • Year and Date: 2014-08-10
  • Invited
• [Presentation] ヒト肝細胞癌組織における癌幹細胞マーカーとしてのCD44v9の検討 (2014)
  • Author(s): 石井真美、梯アンナ、魏民、佐谷秀行、鰐渕英機
  • Organizer: 第11回日本病理学会カンファレンス
  • Place of Presentation: 六甲山ホテル(兵庫県・神戸市)
  • Year and Date: 2014-08-01 – 2014-08-02
• [Presentation] 成人T細胞白血病の基礎免疫研究から発症予防・治療ワクチンへ (2014)
  • Author(s): 神奈木真理
  • Organizer: 第18回日本がん免疫学会モーニングセミナー2(臨床)
  • Place of Presentation: ひめぎんホール(愛媛県、松山市)
  • Year and Date: 2014-08-01
• [Presentation] Mechanism of leukemogenesis by human T-cell leukemia virus type I (2014)
  • Author(s): Masao Matsuoka
  • Organizer: The l2th Annual Meeting of Japanese Society of Medical Oncology
  • Place of Presentation: 福岡サンパレス(福岡県・福岡市)
  • Year and Date: 2014-07-17 – 2014-07-19
  • Invited
• [Presentation] がん関連試料の収集・提供, 神奈川県立がんセンターの腫瘍組織センター事業 (2014)
  • Author(s): 宮城洋平
  • Organizer: 東京慈恵会医科大学・臨床研究セミナー
  • Place of Presentation: 東京慈恵医科大学(東京)
  • Year and Date: 2014-07-14
• [Presentation] 骨微小環境における乳がん細胞の増殖に関与するmicroRNAの同定とその機能解析 (2014)
  • Author(s): 二口充, 深町勝己, 酒々井眞澄
  • Organizer: 第23回日本がん転移学会学術総会シンポジウム
  • Place of Presentation: 金沢市文化ホール・金沢ニューグランドホテル(石川県・金沢市)
  • Year and Date: 2014-07-10
  • Invited
• [Presentation] ATLの病態と発症に関わる分子機構解明の現状 (2014)
  • Author(s): 渡邉俊樹
  • Organizer: HTLV-1セミナー、佐賀県地域医療再生計画事業主催
  • Place of Presentation: ホテルニューオータニ佐賀(佐賀県・佐賀市)
  • Year and Date: 2014-07-04
  • Invited
• [Presentation] 疫学研究での小型活動量計による睡眠時間の推計の可能性 (2014)
  • Author(s): 森田えみ、角谷寛、山田尚登、篠壁多恵、杉本裕香、福田奈菜、須磨紫乃、中川弘子、田村高志、川合紗世、岡田理恵子、菱田朝陽、内藤真理子、浜島信之、若井建志
  • Organizer: 日本睡眠学会第39回定期学術集会
  • Place of Presentation: あわぎんホール(徳島県・徳島市)
  • Year and Date: 2014-07-03
• [Presentation] 化学発がん物質のリスク評価における閾値問題 (2014)
  • Author(s): 福島昭治、魏民、梯アンナ、鰐渕英機
  • Organizer: 第41回日本毒性学会学術年会教育講演
  • Place of Presentation: 神戸コンベンションセンター(兵庫県・神戸市)
  • Year and Date: 2014-07-02 – 2014-07-04
  • Invited
• [Presentation] 小さな巨人「マイクロRNA」によるがん診断およびがん治療戦略 (2014)
  • Author(s): 田原栄俊
  • Organizer: NPO法人国際医科学研究会第8回フォーラム
  • Place of Presentation: フクラシア東京ステーション(東京)
  • Year and Date: 2014-06-29
• [Presentation] 生殖細胞の低温保存技術を利用した遺伝子改変マウス研究基盤の構築 (2014)
  • Author(s): 竹尾透、中潟直己
  • Organizer: 第59回低温生物工学会大会及びセミナー
  • Place of Presentation: 九州大学国際ホール(福岡県・福岡市)
  • Year and Date: 2014-06-28
• [Presentation] PARP阻害剤をめぐる最近の話題(Year in Review) (2014)
  • Author(s): 清宮啓之
  • Organizer: 第18回日本がん分子標的治療学会学術集会
  • Place of Presentation: 仙台市情報・産業プラザ(宮城県・仙台市)
  • Year and Date: 2014-06-27
  • Invited
• [Presentation] PI3K経路阻害剤(Year in Review) (2014)
  • Author(s): 旦慎吾
  • Organizer: 第18回日本がん分子標的治療学会学術集会
  • Place of Presentation: 仙台市情報・産業プラザ(宮城県・仙台市)
  • Year and Date: 2014-06-26
  • Invited
• [Presentation] Liquid Biopsyによる疾患の診断と核酸医薬の開発の現状 (2014)
  • Author(s): 田原栄俊
  • Organizer: PMDA職員研修会
  • Place of Presentation: 独立行政法人医薬品医療機器総合機構(東京)
  • Year and Date: 2014-06-17
  • Invited
• [Presentation] Identification and analysis of large intergenic non-coding RNAs regulated by p53 family members through a genome-wide analysis of p53 binding sites (2014)
  • Author(s): Idogawa M, Ohashi T, Sasaki Y, Tokio T
  • Organizer: 16th International p53 Workshop
  • Place of Presentation: Stockholm, Sweden
  • Year and Date: 2014-06-17
• [Presentation] Genome-based personalized medicine in oncology (2014)
  • Author(s): Tokino T
  • Organizer: The 18th International Congress of Personalized Medicine
  • Place of Presentation: 札幌コンベンションセンター(北海道・札幌市)
  • Year and Date: 2014-06-14
• [Presentation] トレモライトの中皮腫発がん性は高いがアンソフィライトの中皮腫発がん性は低い (2014)
  • Author(s): ディルノル・アルキン、岡崎泰昌、周珊瑚、王越、三澤伸明、豊國伸哉
  • Organizer: 第21回日本がん予防学会総会
  • Place of Presentation: 国立がんセンター研究所築地キャンパス(東京)
  • Year and Date: 2014-06-13 – 2014-06-14
• [Presentation] p53 family network and tumor suppression (2014)
  • Author(s): Sasaki Y, Tamura, M, Takeda K, Idogawa M, Maruyama R, Suzuki H, Shinomura Y, Tokino T
  • Organizer: The 3rd International Symposium on Genetic Regulation and Targeted Therapy of Cancer and 5th Symposium of A3 Foresight Program
  • Place of Presentation: Zhangjiajie, China
  • Year and Date: 2014-06-13
• [Presentation] 「地域住民コホートと老年病研究」(シンポジウム「老年病のコホート研究」) (2014)
  • Author(s): 大中佳三
  • Organizer: 第56回日本老年医学会学術集会
  • Place of Presentation: 福岡国際会議場(福岡県、福岡市)
  • Year and Date: 2014-06-12
• [Presentation] 軽度骨量減少者における動脈壁硬化度の評価とその意義-骨粗鬆症前段階からの骨・血管連関の危険性- (2014)
  • Author(s): 栗山長門、尾﨑悦子、松井大輔、渡邉功、渡邊能行
  • Organizer: 第14回臨床血圧脈波研究会
  • Place of Presentation: 品川インターシティホール(東京)
  • Year and Date: 2014-06-07
• [Presentation] Senescence-associated exosome, the mechanism of secretion and the function (2014)
  • Author(s): Hidetoshi Tahara
  • Organizer: KSEV2014(Korean Society for ExtracellularVesicles)
  • Place of Presentation: EwhaCampus Complex, EwhaWomansUniversity, Seoul, Korea
  • Year and Date: 2014-05-30
  • Invited
• [Presentation] Senescence-associated exosome, the mechanism of secretion and the function (2014)
  • Author(s): Hidetoshi Tahara
  • Organizer: Symposium on Extracellular Vesicles for Biomedical Applications
  • Place of Presentation: Clinical Lecture Hall 2, Seoul National Children's Hospital, Seoul, Korea
  • Year and Date: 2014-05-29
  • Invited
• [Presentation] Functional analysis of the TGF-β pathway in hepatoblasts during mouse hepatic histogenesis. (2014)
  • Author(s): Yokouchi, Y., Yoshii, D., Takeda, H., Suda, H., Inomata, Y., Yamamura, K.
  • Organizer: 第47回日本発生生物学会
  • Place of Presentation: ウインクあいち(愛知県・名古屋市)
  • Year and Date: 2014-05-27 – 2014-05-30
• [Presentation] 個体レベルのがん研究支援-in vivo解析の重要性- (2014)
  • Author(s): 山村研一
  • Organizer: 平成26年度 文部科学省新学術領域研究生命科学系3分野がん・ゲノム・脳支援活動合同シンポジウム
  • Place of Presentation: 一橋大学一橋講堂学術総合センター2F(東京)
  • Year and Date: 2014-05-27
  • Invited
• [Presentation] HTLV-1感染が仕掛ける巧妙な罠 : HBZタンパク質 : 成人T細胞白血病(ATL)と原因ウイルス(HTLV-1)「ATL細胞の培養から始まったHTLV-1研究 (2014)
  • Author(s): 松岡雅雄
  • Organizer: ATLシンポジウム
  • Place of Presentation: 高新文化ホール(高知県・高知市)
  • Year and Date: 2014-05-24
  • Invited
• [Presentation] ATL発症に伴う分子異常、そして難病への取り組み (2014)
  • Author(s): 渡邉俊樹
  • Organizer: ATLシンポジウム-成人T細胞白血病(ATL)と原因ウイルス(HTLV-1)「ATL細胞の培養から始まったHTLV-1研究」、高知大学医学部主催
  • Place of Presentation: 高新文化ホール(高知県・高知市)
  • Year and Date: 2014-05-24
  • Invited
• [Presentation] 認知機能低下を伴う大脳白質病変及びその進行における活性化血小板機能の解析 (2014)
  • Author(s): 栗山長門、水野敏樹、安池博美、松野浩之、河下映里、田邑愛子、尾崎悦子、松井大輔、渡邉功、近藤正樹、徳田隆彦、大島洋一、吉田誠克、村西学、赤澤健太郎、高田明浩、武田和夫、山田惠、中川正法、渡邊能行
  • Organizer: 第55回日本神経学会
  • Place of Presentation: 福岡国際会議場(福岡県・福岡市)
  • Year and Date: 2014-05-22
• [Presentation] Xanthohumol impairs autophagosome maturation through direct inhibition of Valosin-containing protein (2014)
  • Author(s): 井本正哉
  • Organizer: RIKEN-Max Planck Joint Research Center for Systems Chemical Biology 3rd Annual Symposium
  • Place of Presentation: Schloss Ringberg, Germany
  • Year and Date: 2014-05-22
  • Invited
• [Presentation] アスベスト発がんと過剰鉄 : 動物発がんから発症予防へ (2014)
  • Author(s): 豊國伸哉
  • Organizer: 第87回日本産業衛生学会・第84回日本衛生学会
  • Place of Presentation: 岡山コンベンションセンター(岡山県・岡山市)
  • Year and Date: 2014-05-21 – 2014-05-27
  • Invited
• [Presentation] Direct Detection of Exosome by SP6800 Spectral Analyzer, Direct Detection of Exosome by SP6800 Spectral Analyzer (2014)
  • Author(s): 品末聡也、田原栄俊
  • Organizer: CYTO2014
  • Place of Presentation: Greater Fort Lauderdale/Broward County Convention Center, Ft. Lauderdale, Florida, U.S.A.
  • Year and Date: 2014-05-19
• [Presentation] ヒト疾患モデルを用いた病因・病態解析と治療法の検証 (2014)
  • Author(s): 山村研一
  • Organizer: 第61回日本実験動物学会総会
  • Place of Presentation: 札幌コンベンションセンター(北海道・札幌市)
  • Year and Date: 2014-05-15 – 2014-05-17
  • Invited
• [Presentation] 可変型遺伝子トラップクローンデータベース[EGTC]の開発と解析 (2014)
  • Author(s): 荒木正健, 中原舞, 柳井千佳, 山添史雅, 宮家幹子, 森田彩香, 荒木美幸, 岡本瀬幸, 中潟直己, 吉信公美子, 山村研一, 荒木喜美
  • Organizer: 第61回日本実験動物学会総会
  • Place of Presentation: 札幌コンベンションセンター(北海道・札幌市)
  • Year and Date: 2014-05-15 – 2014-05-17
• [Presentation] 遺伝的モニタリング : 過去・現在・未来 (2014)
  • Author(s): 加藤秀樹
  • Organizer: 日本実験動物科学技術2014
  • Place of Presentation: 札幌コンベンションセンター(北海道・札幌市)
  • Year and Date: 2014-05-15 – 2014-05-17
  • Invited
• [Presentation] マウス精巣上体尾部冷蔵保存液の開発 (2014)
  • Author(s): 土山修治、福本紀代子、春口幸恵、近藤朋子、竹下由美、中牟田裕子、梅野智子、高橋郁、古波蔵恵里、竹尾透、Ming-Wen Li、Kristy Kinchen、Jadine Vallelunga、K.C. Kent Lloyd、清水範彦、中潟直己
  • Organizer: 日本実験動物科学技術2014
  • Place of Presentation: 札幌コンベンションセンター(北海道・札幌市)
  • Year and Date: 2014-05-15 – 2014-05-17
• [Presentation] 遺伝子改変マウス凍結精子とC57BL/6J凍結未受精卵子間での体外受精 (2014)
  • Author(s): 梅野智子、福本紀代子、春口幸恵、近藤朋子、竹下由美、中牟田裕子、岩本まり、高橋郁、古波蔵恵里、土山修治、竹尾透、中潟直己
  • Organizer: 日本実験動物科学技術2014
  • Place of Presentation: 札幌コンベンションセンター(北海道・札幌市)
  • Year and Date: 2014-05-15 – 2014-05-17
• [Presentation] Understanding pediatric cancer development by studying induced pluripotency (2014)
  • Author(s): Yamada Y.
  • Organizer: ADVANCES IN NEUROBLASTOMA RESEARCH
  • Place of Presentation: Colonge, Germany
  • Year and Date: 2014-05-13 – 2014-05-16
  • Invited
• [Presentation] Connectivity mapデータベースを利用した化合物スクリーニングのアルゴリズム開発 (2014)
  • Author(s): 牛嶋大、冨田章弘、斎藤さかえ、野田哲生、松浦正明
  • Organizer: 文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウム アカデミアからの抗がん剤創薬に向けて―天然物の有効利用
  • Place of Presentation: 万国津梁館(沖縄県・名護市)
  • Year and Date: 2014-05-12
• [Presentation] ヒトがん細胞パネルJFCR39による化合物の活性評価 (2014)
  • Author(s): 山崎佳波、矢守隆夫、旦慎吾
  • Organizer: 文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
  • Place of Presentation: 万国津梁館(沖縄県・名護市)
  • Year and Date: 2014-05-12
• [Presentation] 化学療法基盤支援活動におけるプロテインキナーゼ阻害剤活性の評価(Ⅱ) (2014)
  • Author(s): 福山まり、深澤秀輔
  • Organizer: 文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
  • Place of Presentation: 万国津梁館(沖縄県・名護市)
  • Year and Date: 2014-05-12
• [Presentation] 化学療法基盤支援活動「プロテインキナーゼ(PK)阻害活性の評価」 (2014)
  • Author(s): 西谷直之、岩尾正倫、上原至雅
  • Organizer: 文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
  • Place of Presentation: 万国津梁館(沖縄県・名護市)
  • Year and Date: 2014-05-12
• [Presentation] サブタイプ選択的なHDACアッセイ系を用いたbicyclic depsipeptide HDAC阻害剤のサブタイプ選択性の評価 (2014)
  • Author(s): 中田明子、伊藤昭博、加藤正、吉田稔
  • Organizer: 文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
  • Place of Presentation: 万国津梁館(沖縄県・名護市)
  • Year and Date: 2014-05-12
• [Presentation] 化合物活性予測のための遺伝子発現データベース構築 (2014)
  • Author(s): 田代悦、大嶽弘之、井本正哉
  • Organizer: 文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
  • Place of Presentation: 万国津梁館(沖縄県・名護市)
  • Year and Date: 2014-05-12
• [Presentation] 再燃性前立腺がんにおける短鎖型アンドロゲン受容体の役割とその制御物質 (2014)
  • Author(s): 岡部幸子、馬島哲夫、清宮啓之
  • Organizer: 文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
  • Place of Presentation: 万国津梁館(沖縄県・名護市)
  • Year and Date: 2014-05-12
• [Presentation] 化学療法基盤支援活動が無償配布する化合物ライブラリー (2014)
  • Author(s): 川田学
  • Organizer: 文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
  • Place of Presentation: 万国津梁館(沖縄県・名護市)
  • Year and Date: 2014-05-12
• [Presentation] 理研天然化合物バンクNPDepoの構築と活用 (2014)
  • Author(s): 長田裕之
  • Organizer: 文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
  • Place of Presentation: 万国津梁館(沖縄県・名護市)
  • Year and Date: 2014-05-12
• [Presentation] 理化学研究所天然化合物(NPDepo)が提供する創薬研究支援 (2014)
  • Author(s): 斎藤臣雄、近藤恭光、長田裕之
  • Organizer: 文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
  • Place of Presentation: 万国津梁館(沖縄県・名護市)
  • Year and Date: 2014-05-12
• [Presentation] がん分子標的薬開発の状況とシード探索法 (2014)
  • Author(s): 水上民夫
  • Organizer: 文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
  • Place of Presentation: 万国津梁館(沖縄県・名護市)
  • Year and Date: 2014-05-12
• [Presentation] がん分子標的創薬を指向した低酸素誘導因子(HIF)阻害剤の探索・開発研究 (2014)
  • Author(s): 嶋田清香、吉村彩、安田順信、高橋伸明、西村慎一、服部明、掛谷秀昭
  • Organizer: 文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
  • Place of Presentation: 万国津梁館(沖縄県・名護市)
  • Year and Date: 2014-05-12
• [Presentation] 高速細胞スキャナーを用いた3次元培養による抗がん剤スクリーニング法の開発 (2014)
  • Author(s): 水上民夫、東郷有希、細井美穂、長谷川慎、佐々木隆造、藤本博己、生藤邦夫
  • Organizer: 文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
  • Place of Presentation: 万国津梁館(沖縄県・名護市)
  • Year and Date: 2014-05-12
• [Presentation] タンパク質脂質修飾酵素によるWnt/β-cateninシグナルの制御 (2014)
  • Author(s): 西谷直之、奥裕介、上原至雅
  • Organizer: 文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
  • Place of Presentation: 万国津梁館(沖縄県・名護市)
  • Year and Date: 2014-05-12
• [Presentation] ゴルジ体阻害化合物の3D-QSARに基づくFragment-Based In Silico Screening (2014)
  • Author(s): 内田太郎、山乙教之、広野修一、江頭直樹、椎名勇、藤本晶子、守谷潤、大橋愛美、旦慎吾、矢守隆夫
  • Organizer: 文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
  • Place of Presentation: 万国津梁館(沖縄県・名護市)
  • Year and Date: 2014-05-12
• [Presentation] 全合成ゴルジ阻害剤M-COPAの抗がん活性 (2014)
  • Author(s): 大橋愛美、椎名勇、旦慎吾、矢守隆夫
  • Organizer: 文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
  • Place of Presentation: 万国津梁館(沖縄県・名護市)
  • Year and Date: 2014-05-12
• [Presentation] 乳がん細胞の増殖におけるメチル化リジン結合タンパク質CBX2の重要性の解明 (2014)
  • Author(s): 伊藤昭博、波多野稔子、Muhammad Muddassar、Kam Zhan、吉田稔
  • Organizer: 文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
  • Place of Presentation: 万国津梁館(沖縄県・名護市)
  • Year and Date: 2014-05-12
• [Presentation] 神経膠腫幹細胞に対するテロメスタチン誘導体の選択的な抗腫瘍効果 (2014)
  • Author(s): 中村貴大、岡部幸子、飯田圭介、矢守隆夫、新家一男、中野伊知郎、長澤和夫、清宮啓之
  • Organizer: 文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
  • Place of Presentation: 万国津梁館(沖縄県・名護市)
  • Year and Date: 2014-05-12
• [Presentation] Biogenesis and biological activity of exosomes in replicative senescent cells (2014)
  • Author(s): Megumi Okada, Ayumi Nakamura, Misa Muneoka, Nao Nitta, Hidetoshi Tahara
  • Organizer: ISEV(INTERNATIONAL SOCIETY FOR EXTRACELLULAR VESICLES)2014
  • Place of Presentation: ロッテルダム、オランダ
  • Year and Date: 2014-05-01
• [Presentation] 骨微小環境におけるがん細胞の増殖メカニズム (2014)
  • Author(s): 二口充
  • Organizer: 第87回日本内分泌学会学術総会シンポジウム
  • Place of Presentation: 福岡サンパレス(福岡県・福岡市)
  • Year and Date: 2014-04-26
  • Invited
• [Presentation] 東大医科研における橋渡し研究とその発展 (2014)
  • Author(s): 今井浩三
  • Organizer: 第103回日本病理学会総会 特別企画
  • Place of Presentation: 広島国際会議場フェニックスホール(広島県・広島市)
  • Year and Date: 2014-04-24 – 2014-04-26
  • Invited
• [Presentation] マウス肺扁平上皮癌において気管支肺胞幹細胞がオリジンである可能性 (2014)
  • Author(s): 山野荘太郎、魏民、藤岡正喜、鰐渕英機
  • Organizer: 第103回日本病理学会総会
  • Place of Presentation: 広島国際会議場(広島県・広島市)
  • Year and Date: 2014-04-24 – 2014-04-26
• [Presentation] ヒト肝細胞癌におけるLC-MS/MS及びin vitro機能解析を用いた新規特異的候補分子ターゲットの検討 (2014)
  • Author(s): 梯アンナ、桑江優子、石井真美、魏民、鰐渕英機
  • Organizer: 第103回日本病理学会総会
  • Place of Presentation: 広島国際会議場(広島県・広島市)
  • Year and Date: 2014-04-24 – 2014-04-26
• [Presentation] EHEN誘発ラット腎発がんにおいて内因性NADPH oxidase阻害剤apocy-ninは抑制作用を有する (2014)
  • Author(s): 三島胡桃、山野荘太郎、藤岡正喜、魏民、鰐渕英機
  • Organizer: 第103回日本病理学会総会
  • Place of Presentation: 広島国際会議場(広島県・広島市)
  • Year and Date: 2014-04-24 – 2014-04-26
• [Presentation] 非B非C型肝細胞がんの病理学的解析 (2014)
  • Author(s): 神田浩明、鹿取正道、山本智理子、マハムットヤセン、齋浦明夫、石川雄一、加藤洋、北川知行
  • Organizer: 第103回日本病理学会総会
  • Place of Presentation: 広島国際会議場(広島県・広島市)
  • Year and Date: 2014-04-24 – 2014-04-26
• [Presentation] 発がん要因としての酸化ストレス シンポジウム1 : 腫瘍病理学の真髄 (2014)
  • Author(s): 豊國伸哉
  • Organizer: 第103回日本病理学会総会
  • Place of Presentation: 広島国際会議場(広島県・広島市)
  • Year and Date: 2014-04-24
  • Invited
• [Presentation] ヒト腫瘍の原因について病理はなにができるか (2014)
  • Author(s): 椙村春彦
  • Organizer: 第103回日本病理学会総会
  • Place of Presentation: 広島国際会議場(広島県・広島市)
  • Year and Date: 2014-04-24
• [Presentation] 疾患感受性遺伝子による2型糖尿病発症予測の検討 (2014)
  • Author(s): 大中佳三、河野倫子、山本健、河手久弥、野村政壽、古野純典、井口登與志、高柳涼一
  • Organizer: 第87回日本内分泌学会学術集会
  • Place of Presentation: 福岡国際会議場(福岡県・福岡市)
  • Year and Date: 2014-04-24
• [Presentation] ATL発症とプログレッションの分子基盤解明の試み (2014)
  • Author(s): 渡邉俊樹
  • Organizer: ATL small meeting、協和発酵キリン(株)主催
  • Place of Presentation: ホテルモントレー仙台(宮城県・仙台市)
  • Year and Date: 2014-04-18
  • Invited
• [Presentation] Growth of malignant tumor in the bone microenvironment (2014)
  • Author(s): Futakuchi, M.
  • Organizer: 2014 Seoul National University Cancer Research Institute, Cancer Symposium
  • Place of Presentation: Mokpo, Korea
  • Year and Date: 2014-04-16
  • Invited
• [Presentation] 東京大学医科学研究所におけるTRの現状と展望. シンポジウム2「我が国におけるトランスレーショナルリサーチの現状とこれからの展望」 (2014)
  • Author(s): 今井浩三
  • Organizer: 第51回日本臨床分子医学会学術集会
  • Place of Presentation: 東京国際フォーラム(東京)
  • Year and Date: 2014-04-11 – 2014-04-12
  • Invited
• [Presentation] Human colorectal cancer marker PC(16:0/16:1)induces cell growth by activating Akt and Erk pathways (2014)
  • Author(s): Nobuya Kurabe, Toshio Nakamura, Kiyotaka Kurachi, Tomoaki Kahyo, Kazuya Shinmura, Mitsutoshi Setou, Haruhiko Sugimura
  • Organizer: The 105th AACR Annual Meeting
  • Place of Presentation: San Diego, U.S.A.
  • Year and Date: 2014-04-07
• [Presentation] Forkhead transcription factor FOXFI is a novel target gene of the p53 family and regulates cancer cell migration and invasiveness (2014)
  • Author(s): Tokino T, Tamura M, Idogawa M, Sasaki Y
  • Organizer: American Association of Cancer Research (AACR) Annual Meeting
  • Place of Presentation: San Diego, U.S.A.
  • Year and Date: 2014-04-06
• [Book] 実験動物の感染症と微生物モニタリング (2015)
  • Author(s): 高倉彰, 他
  • Total Pages: 102
  • Publisher: ㈱アドスリー
• [Book] 臨床病理63(1), ヒトがん関連試料の提供事業に於ける質の管理 : 神奈川がん臨床研究・情報機構での経験から (2015)
  • Author(s): 宮城洋平
  • Total Pages: 111-118
  • Publisher: 克誠堂出版
• [Book] 最新がん薬物療法学 (2015)
  • Author(s): 北川光洋、田代悦、井本正哉
  • Total Pages: 704(90-96)
  • Publisher: (株)日本臨床社
• [Book] ゲノム解析に基づく新しい分子標的治療 : ゲノムワイドな解析および統合的解析による前立腺がん幹細胞の分子標的探索(「がん分子標的治療」) (2015)
  • Author(s): 馬島哲夫、清宮啓之
  • Total Pages: 116(52-56)
  • Publisher: メディカルレビュー社
• [Book] 「繊維性ナノマテリアルの発がん機構」-職業・環境発がん : メカニズムと病理-『病理と臨床』2014年6月号(32巻6号) (2014)
  • Author(s): 豊國伸哉(編集)
  • Total Pages: 116
  • Publisher: 文光堂
• [Book] 「浸潤と転移」『新臨床腫瘍学(改訂第4版)-がん薬物療法専門医のために-』 (2014)
  • Author(s): 二口充
  • Total Pages: 4
  • Publisher: 南光堂
• [Book] 酸化ストレスを標的とした治療開発 (2014)
  • Author(s): 塩田真己、横溝晃、内藤誠二
  • Total Pages: 2131-2135
  • Publisher: 日本臨牀
• [Book] 「成人T細胞白血病に対する免疫療法～AZT/IFN-α、骨髄移植、樹状細胞ワクチン～」『血液フロンティア』2014年11月号(Vol.24 No.11) (2014)
  • Author(s): 神奈木真理、長谷川温彦、金原秀一、末廣陽子
  • Total Pages: 1631-1638
  • Publisher: 医薬ジャーナル社
• [Book] 血液内科医・皮膚科医のための統合ATL診療ガイドライン解説書2014、124巻12号 (2014)
  • Author(s): 石田高司、伊藤旭、戸倉新樹、田中淳司、鵜池直邦、飛内賢正、塚崎邦弘
  • Total Pages: 2275-2279
  • Publisher: 日本皮膚科学会雑誌
• [Book] Human T-cell leukemia virus type 1 : pathogenesis and host immune response. Viruses and human cancers, edited by Hudnall, SD (2014)
  • Author(s): Yasunaga JI and Matsuoka M
  • Total Pages: 229-262
  • Publisher: Springer
• [Book] 「ヒトT細胞白血病ウイルス1型感染症(Human T-cell leukemia virus type Infection)」J. RNAウイルス感染症、Ⅲ章. 主要な感染症(原因微生物毎)、-感染症診療update-『日本医師会雑誌』143巻・特別号(2) (2014)
  • Author(s): 渡邉俊樹
  • Total Pages: 394-397
  • Publisher: 日本医師会
• [Book] 「マイクロRNA発現異常とHTLV-1による成人T細胞白血病(ATL)発症」特集マイクロRNAと血液疾患『血液内科』68(6) (2014)
  • Author(s): 渡邉俊樹
  • Total Pages: 781-785
  • Publisher: 科学評論社
• [Book] The Role of DNA Methylation in the Genetics and Epigenetics of Multiple Myelome (2014)
  • Author(s): Yasui H, Ishida T, Imai K
  • Total Pages: 249(147-156)
  • Publisher: Nova Science Publishers
• [Book] 特集オートファジーに挑むケミカルバイオロジー「天然物化学とケミカルバイオロジーの挑戦」 (2014)
  • Author(s): 田代悦、井本正哉
  • Total Pages: 79(22-27)
  • Publisher: (株)化学工業社
• [Book] がん細胞パネルーバイオインフォマティクスによる新たな分子標的抗がん剤創薬とバイオマーカー探索(「最新がん薬物療法学-がんの薬物療法の最新知見-」) (2014)
  • Author(s): 旦慎吾
  • Total Pages: 710(102-108)
  • Publisher: 日本臨牀
• [Book] Clinical Genomicsを目指した半導体NGSによるがんゲノム解析. 実験医学32(11) (2014)
  • Author(s): 丸喜明、佐々木泰史、中村友紀、横井左奈、大平美紀、時野隆至、永瀬浩喜
  • Total Pages: 8ページ(1781-1788)
  • Publisher: 羊土社
• [Book] 大腸腺腫と大腸鋸歯状病変における遺伝子異常と生活習慣の関連 (2014)
  • Author(s): 五十嵐央祥、能正勝彦、伊藤美樹、篠村恭久
  • Total Pages: 7ページ(605-611)
  • Publisher: 先端医学社
• [Remarks] がん研究分野の特性等を踏まえた支援活動
  • URL: http://ganshien.umin.jp/
• [Remarks] がん研究分野の特性等を踏まえた支援活動 ホーム>研究紹介>インタビュー>豊國伸哉教授
  • URL: http://ganshien.umin.jp/research/main/toyokuni/index.html
• [Remarks] J-MICC STUDY/日本多施設共同コーホート研究(ジェイミック スタディ)
  • URL: http://www.jmicc.com
• [Remarks] 京都府立医科大学大学院医学研究科 地域保健医療疫学のホームページ
  • URL: http://www.f.kpu-m.ac.jp/k/epid/index.html
• [Remarks] J-MICC Study(ジェイミック・スタディ)佐賀フィールドとは
  • URL: http://www.prevent.med.saga-u.ac.jp/jmiccsaga.html
• [Remarks] 鹿児島大学大学院医歯学総合研究科 国際島嶼医療学講座「研究の紹介」
  • URL: http://www.kufm.kagoshima-u.ac.jp/~islands/
• [Remarks] 国際教養学部開設記念シンポジウム(5/13)
  • URL: http://www.juntendo.ac.jp/event/20150513-00000102.html
• [Remarks] 研究紹介がん疫学・予防支援活動「倫理的・法的・社会的諸問題(ELSI)」の支援
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  • URL: http://www.med.nagoya-u.ac.jp/yobo/jmicc_shizuoka/
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• [Remarks] 浜松医大病理学講座がん支援活動ホームページ
  • URL: http://www.hama-med.ac.jp/uni_education_igakubu_igaku_byouril_ganshienkenkyu.html
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  • URL: http://epi.ncc.go.jp/spF/index.html
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• [Patent(Industrial Property Rights)] 染色バスケット (2014)
  • Inventor(s): 加茂隆春・椙村春彦・門畑一久
  • Industrial Property Rights Holder: 浜松医科大学
  • Industrial Property Rights Type: 特許特願2014-157406
  • Industrial Property Number: 特願2014-157406
  • Filing Date: 2014-08-01
  • Application Year: 2014
• [Patent(Industrial Property Rights)] HTLV-1関連疾患の予防及び/又は治療用ワクチン (2014)
  • Inventor(s): 松岡雅雄、菅田謙治
  • Industrial Property Rights Holder: 京都大学
  • Industrial Property Rights Type: 特許特願2014-155855
  • Industrial Property Number: 特願2014-155855
  • Filing Date: 2014-07-31
  • Application Year: 2014