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2014 Fiscal Year Annual Research Report

がん研究分野の特性等を踏まえた支援活動

Research Project

Project Areaがん研究分野の特性等を踏まえた支援活動
Project/Area Number 221S0001
Research InstitutionThe University of Tokyo

Principal Investigator

今井 浩三  東京大学, 医科学研究所, 特任教授 (60117603)

Co-Investigator(Kenkyū-buntansha) 中村 卓郎  公益財団法人がん研究会, がん研究所・発がん研究部, 副所長 (00180373)
山村 研一  熊本大学, 生命資源研究・支援センター, シニア教授 (90115197)
田中 英夫  愛知県がんセンター(研究所), ・疫学・予防部, 部長 (60470168)
神奈木 真理  東京医科歯科大学, 大学院医歯学総合研究科, 教授 (80202034)
醍醐 弥太郎  東京大学, 医科学研究所, 特任教授 (30345029)
Project Period (FY) 2010-04-01 – 2016-03-31
Keywords若手支援 / 国際研究者交流 / 遺伝子改変マウス / 病理形態学 / ゲノムコーホート研究 / 個別化がん予防 / 次世代分子解析技術 / アカデミア創薬
Outline of Annual Research Achievements

総括支援 : 公開シンポジウム、ワークショップ(日独、日韓、がん若手 : 82名参加・発表)、青少年市民公開講座開催。がん研究読本④・⑤をネット出版。
個体レベルでのがん研究支援 : Tg作製4件、ゲノム編集関連61件、ES関連103件、個体でのアレル変換42件、微生物モニタリング427検体、遺伝モニタリング2732検体、凍結保存50系統、病理形態学31件、ワークショップ1回支援した。
がん疫学・予防研究支援 : 10万1千名の研究者提供生体試料を用いた研究支援。テロメア長測定支援5、aberrant crypt fosiをバイオマーカーとした大腸癌予防介入試験支援6、肥満と肝発癌関連実験モデル作成等がん予防への研究支援を行った。HTLV-1研究支援 : 患者検体の免疫解析、プロウイルス量測定、抗ATLワクチン療法や抗CCR4抗体療法の後方支援、HTLV-1関連単クロン抗体の製造管理・供与、患者登録システムJSPFAD(9000検体以上)の維持運営、検体供与を行った。
臨床診断研究支援 : 組織・FFPE975、血清・DNA1583のがん試料収集、4研究者に計379を提供した。膵臓がん258例からなる組織アレイを構築。各種診断法検証支援で論文13編に貢献した。組織バンク、技術支援と啓蒙講演を実施した。
化学療法基盤支援 : 依頼化合物102点の作用機序・分子標的阻害活性評価、延べ714件。阻害剤キット・化合物ライブラリー整備拡充・提供227枚。薬効関連遺伝子発現・新薬開発情報等のDB整備を拡充し公開した。創薬関連シンポジウムを2回開催した。
ゲノム・エピゲノム解析支援 : がん関連の409遺伝子変異等について17研究者から376検体を解析、DNAメチル化解析等について7研究者から延べ1490検体の解析、マイクロRNA発現解析等について4研究者から延べ270検体の解析を行った。

Current Status of Research Progress
Current Status of Research Progress

1: Research has progressed more than it was originally planned.

Reason

各支援活動とも、計画に沿って順調に支援を続けているが、以下の活動では計画以上の進展を示した。若手研究者支援では、「がん特定領域研究」時代以来の継続による積極的取組が功を奏し、がん研究を初めとする医学生物学系においてリーダーとなる人材が輩出するようになってきたが、本年度もこの流れは継続している。国際交流活動ではフランス、韓国、ドイツとの二国間ワークショッップを本年度実施する等、相互交流がより活発となり、共同研究や人材交流が一層盛んになっている。広報活動として、がん研究の現状を一般にわかりやすく解説したネット出版物「がん研究読本」も巻を5まで重ね、好評を得ている。また、高校生を対象としたキャンサーセミナーを盛岡市にて実施した。がん疫学・予防支援活動では、多施設共同コホート研究で10万人のリクルートを達成した。
一方、研究者のネットワーク構築を背景として、臨床診断研究支援を初めとするがん研究者への支援から世界をリードするがん研究の論文成果が着実に挙げられている。さらに、脳・ゲノム支援活動との連携促進による生命科学系3分野としての活動が着実に進行し、これまでに3回の合同シンポジウムを開催した。特にモデル動物に関する情報交換を行って共通のデータベース立ち上げへの道を開くとともに、技術面での意見交換も行った。平成24年度から追加されたゲノム・エピゲノム解析支援も活動が進展し、患者サンプル及びモデル動物の遺伝子異常解析支援が順調に行われている。

Strategy for Future Research Activity

平成22~26年度の支援活動をより強固に継続するとともに、若手研究者を中心として、科研費採択課題に対する、より広い分野の研究を対象とした積極的な支援を行う。がん若手研究シンポジウム及び、日仏・日韓の2国間がんワークショップは本年も開催を予定しているが、今後の発展を見据えて育成・交流の成果を挙げたい。個体レベルの研究支援においては、CRISPR/Cas9に代表される最新テクノロジーを利用したモデル動物開発を既に開始しているので、その成績を見極めるとともに、がんと再生・幹細胞研究、脳研究との連携を推進する。また、個体レベルのがん研究ワークショップを引き続き開催して、支援の成果を公表する。がん疫学・予防支援では、コホート研究で得られた試料のがん研究への利用を倫理面での評価を行いながら更に推進する。臨床診断研究支援では、プロテオーム解析や組織アレイのさらなる充実化を図り、がん研究者へのヒト検体を用いた解析を支援することで、世界レベルの研究成果の増産を目指す。化学療法基盤支援活動では、がん研究分野以外への支援も視野に入れた化合物の評価・スクリーニングを進める。がんゲノム・エピゲノム解析支援活動では、上述のように支援体制が整備されたので、ヒト検体・モデル動物検体に対する、遺伝子変異パネルの解析を推進する。
また、生命科学系3分野間の連携を一層促進し、今後の自然科学系の具体的な推進策を立案する。特に、本支援活動が、ボトムアップ支援と最先端技術を開発と一体化した体制を構築するよう検討を進める。

  • Research Products

    (574 results)

All 2016 2015 2014 Other

All Journal Article (279 results) (of which Peer Reviewed: 274 results,  Open Access: 2 results,  Acknowledgement Compliant: 2 results) Presentation (262 results) (of which Invited: 54 results) Book (17 results) Remarks (14 results) Patent(Industrial Property Rights) (2 results)

  • [Journal Article] Impact of metallothionein gene polymorphisms on the risk of lung cancer in a Japanese population2016

    • Author(s)
      Nakane H, Hirano M, Ito H, Hosono S, Oze I, Matsuda F, Tanaka H, Matsuo K.
    • Journal Title

      Mol Carcinog

      Volume: 54(S1) Pages: E122-E128

    • DOI

      10.1002/mc.22198

    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes2016

    • Author(s)
      Matsuo H, Yamamoto K, Nakaoka H, Nakayama A, Sakiyama M, Chiba T, Takahashi A, Nakamura T, Nakashima H, Takada Y, Danjoh I, Shimizu S, Abe J, Kawamura Y, Terashige S, Ogata H, Tatsukawa S, Yin G, Okada R, Morita E, Naito M, Tokumasu A, et al.
    • Journal Title

      Ann Rheum Dis

      Volume: 75 Pages: 652-659

    • DOI

      10.1136/annrheumdis-2014-206191

    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Panitumumab for locally advanced head and neck squamouse-cell carcinoma2015

    • Author(s)
      Ishiki H, Iwase S, Shimada N, Chiba T, Imai K
    • Journal Title

      Lancet Oncology

      Volume: 16 Issue: 4 Pages: e156

    • DOI

      10.1016/S1470-2045(15)70101-4

    • Peer Reviewed
  • [Journal Article] Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis2015

    • Author(s)
      Mitsuhashi K, Nosho K, Sukawa Y, Matsunaga Y, Ito M, Kurihara H, Kanno S, Igarashi H, Naito T, Adachi Y, Tachibana M, Tanuma T, Maguchi H, Shinohara T, Hasegawa T, Imamura M, Kimura Y, Hirata K, Maruyama R, Suzuki H, Imai K, Yamamoto H, Shinomura Y
    • Journal Title

      Oncotarget

    • Description
      【掲載確定】 in press
    • Peer Reviewed
  • [Journal Article] Microsatellite instability : an update2015

    • Author(s)
      Yamamoto H, Imai K
    • Journal Title

      Archives of Toxicology

    • Description
      【掲載確定】 in press
    • Peer Reviewed
  • [Journal Article] Screening of drugs to treat 8p11 myeloproliferative syndrome using patient-derived induced pluripotent stem cells with fusion gene CEP110-FGFR12015

    • Author(s)
      Yamamoto S, Otsu M, Matsuzaka E, Konishi C, Takagi H, Hanada S, Mochizuki S, Nakauchi H, Imai K, Tsuji K, Ebihara Y
    • Journal Title

      Plos One

    • Description
      【掲載確定】 in press
    • Peer Reviewed
  • [Journal Article] Clinicopathological and molecular characteristics of serrated lesions in Japanese elderly patients2015

    • Author(s)
      Nosho K, Igarashi H, Ito M, Mitsuhashi K, Kurihara H, Kanno S, Yoshii S, Mikami M, Takahashi H, Kusumi T, Hosokawa M, Sukawa Y, Adachi Y, Hasegawa T, Okita K, Hirata K, Maruyama R, Suzuki H, Imai K, Yamamoto H, Shinomura Y
    • Journal Title

      Digestion

      Volume: 91 Issue: 1 Pages: 57-63

    • DOI

      10.1159/000368820

    • Peer Reviewed
  • [Journal Article] Contextual niche signals towards colorectal tumor progression by mesenchymal stem cell in the mouse xenograft model2015

    • Author(s)
      Nakagaki S, Arimura Y, Nagaishi K, Isshiki H, Nasuno M, Watanabe S, Idogawa M, Yamashita K, Naishiro Y, Adachi Y, Suzuki H, Fujimiya M, Imai K, Shinomura Y
    • Journal Title

      J Gastroenterol

    • Description
      【掲載確定】 Epub ahead of print
    • Peer Reviewed
  • [Journal Article] 抗体医薬2015

    • Author(s)
      安井寛, 今井浩三
    • Journal Title

      DDS研究30年

      Volume: PHARMA TECH JAPAN 臨時増刊号,31(2) Pages: 94-101

    • Peer Reviewed
  • [Journal Article] 抗体治療 特集「DDSがもたらした新しい臨床の風景」2015

    • Author(s)
      佐々木茂, 篠村恭久, 今井浩三
    • Journal Title

      Drug Delivery System

      Volume: 30 Issue: 1 Pages: 16-24

    • Peer Reviewed
  • [Journal Article] Schwann cells contribute to neurodegeneration of transthyretin amyloidosis2015

    • Author(s)
      Murakami, T., Sango, K., Watabe, K., Niimi, N., Takaku, S., Li, Z, Yamamura, K., Sunada, Y.
    • Journal Title

      J. Neurochem

    • DOI

      10.1111/jnc.13068

    • Description
      in press
    • Peer Reviewed
  • [Journal Article] CHF5074(CSP-1103)stabilizes human transthyretin in mice humanized at the transthyretin and retinol-binding protein loci2015

    • Author(s)
      Mu, Y., Jin, S., Shen, J., Sugano, A., Takaoka, Y., Qiang, L., Imbimbo, B.P., Yamamura, K. and Li, Z.
    • Journal Title

      FEBS letters

    • DOI

      10.1016/j.febslet.2015.02.020

    • Description
      in press
    • Peer Reviewed
  • [Journal Article] Requirement of DLG1 for cardiovascular development and tissue elongation during cochlear, enteric, and skeletal development : possible role in convergent extension2015

    • Author(s)
      Iizuka-Kogo, A., Senda, T., Akiyama, T., Shimomura, A., Nomura, R., Hasegawa, Y., Yamamura, K., Kogo, H., Sawai, N. and Matsuzaki, T.
    • Journal Title

      Plos One

    • Description
      in press
    • Peer Reviewed
  • [Journal Article] Roles of hepatic glucokinase in intertissue metabolic communication : examination of novel liver-specific glucokinase knockout mice2015

    • Author(s)
      Hayashi, H., Sato, Y., Li, Z., Yamamura, K, Yoshizawa, T. and Yamagata, K.
    • Journal Title

      Biochem. Biophys. Res. Commun

    • DOI

      10.1016/j.bbrc.2015.03.097

    • Description
      in press
    • Peer Reviewed
  • [Journal Article] Determining c-Myb protein levels can isolate functional hematopoietic stem cell subtypes2015

    • Author(s)
      Sakamoto, H, Takeda, N, Arai, F, Hosokawa, K, Garcia, P, Suda, T, Frampton, J, Ogawa, M
    • Journal Title

      Stem Cells

      Volume: 2 Pages: 479-490

    • DOI

      10.1002/stem.1855

    • Peer Reviewed
  • [Journal Article] Meikin is a conserved regulator of meiosis-I-specific kinetochore function2015

    • Author(s)
      Kim, J, Ishiguro, K, Nambu, A, Akiyoshi, B, Yokobayashi, S, Kagami, A, Ishiguro, T, Pendas, A.M., Takeda, N, Sakakibara, Y, Kitajima, T.S., Tanno, Y, Sakuno, T, Watanabe, Y
    • Journal Title

      Nature

      Volume: 517 Pages: 466-471

    • DOI

      10.1038/nature14097

    • Peer Reviewed
  • [Journal Article] Cysteine analogs with a free thiol group promote fertilization by reducing disulfide bonds in the Zona Pellucida of mice2015

    • Author(s)
      Takeo, T., Horikoshi, Y., Nakao, S., Sakoh, K., Ishizuka, Y., Tsutsumi, A., Fukumoto, K., Kondo, T., Haruguchi, Y., Takeshita, Y., Nakamuta, Y., Tsuchiyama, S. and Nakagata, N.
    • Journal Title

      Biol. Reprod.

      Volume: 92(4)90 Pages: 1-7

    • DOI

      10.1095/biolreprod.114.125443

    • Peer Reviewed
  • [Journal Article] Minimal inflammogenicity of pristine single-wall carbon nanotubes2015

    • Author(s)
      Toyokuni, S, Jiang, L, Kitaura, R and Shinohara, S
    • Journal Title

      Nagoya J Med Sci

      Volume: 77 Pages: 195-202

    • DOI

      10.3389/fphar.2014.00200

    • Peer Reviewed
  • [Journal Article] Percutaneous Carbon Dioxide Treatment using a Gas Mist Generator Enhances the Collateral Blood Flow in the Ischemic Hindlimb2015

    • Author(s)
      Izumi, Y, Yamaguchi, T, Yamazaki, T, Yamashita, N, Nakamura, Y, Shiota, M, Tanaka, M, Sano, S, Osada-Oka, M, Shimada, K, Wanibuchi, H, Miura, K, Yoshiyama, M, Iwao, H
    • Journal Title

      J Atheroscler Thromb

      Volume: 22 Pages: 38-51

    • DOI

      10.5551/jat.23770

    • Peer Reviewed
  • [Journal Article] Paraneoplastic Ma Antigen-Like 1 as a Potential Prognostic Biomarker in Human Pancreatic Ductal Adenocarcinoma2015

    • Author(s)
      Kuwae, Y, Kakehashi, A, Wakasa, K, Wei, M, Yamano, S, Ishii, N, Ohsawa, M, Wanibuchi, H
    • Journal Title

      Pancreas

      Volume: 44 Pages: 106-115

    • Peer Reviewed
  • [Journal Article] Determination of Hepatotoxicity and Its Underlying Metabolic Basis of 1,2-dichloropropane in Male Syrian Hamsters and B6C3F1 Mice2015

    • Author(s)
      Wei, M, Fujioka, M, Yamano, S, Shimomura, E, Ishii, N, Kakehashi, A, Takeshita, M, Wanibuchi, H
    • Journal Title

      Toxicol. Sci

    • Description
      in press
    • Peer Reviewed
  • [Journal Article] Inhibition of β-catenin and STAT3 with curcumin analog suppresses gastric carcinogenesis in vivo : a novel candidate for gastric cancer treatment2015

    • Author(s)
      Uehara, Y., Inoue, M., Fukuda, K., Yamakoshi, H., Hosoi, Y., Kanda, H., Oshima, M., Iwabuchi, Y., Shibata, H.
    • Journal Title

      Gastric Cancer

    • DOI

      10.1007/s10120-014-0434-3

    • Description
      in press
    • Peer Reviewed
  • [Journal Article] NPT1/SLC17A1 is a renal urate exporter in humans and its common gain-of-function variant decreases the risk of renal underexcretion gout2015

    • Author(s)
      Chiba, T., Matsuo H., Kawamura Y., Nagamori S., Nishiyama T., Wei L., Nakayama A., Nakamura T., Sakiyama M., Takada T., Taketani Y., Suma S., Naito M., Oda T., Kumagai H., Moriyama Y., Ichida K., Shimizu T., Kanai Y. and Shinomiya N.
    • Journal Title

      Arthritis Rheumatol

      Volume: 67 Pages: 281-287

    • DOI

      10.1002/art.38884

    • Peer Reviewed
  • [Journal Article] Common variant of ALPK1 is not associated with gout : a replication study2015

    • Author(s)
      Chiba, T., Matsuo H., Sakiyama M., Nakayama A., Shimizu S., Wakai K., Suma S., Nakashima H., Sakurai Y., Shimizu T., Ichida K. and Shinomiya N.
    • Journal Title

      Hum Cell

      Volume: 28 Pages: 1-4

    • DOI

      10.1007/s13577-014-0103-1

    • Peer Reviewed
  • [Journal Article] HLA-A SNPs and amino acid variants are associated with nasopharyngeal carcinoma in Malaysian Chinese2015

    • Author(s)
      Chin, Y.M., Mushiroda T., Takahashi A., Kubo M., Krishnan G., Yap L.F., Teo S.H., Lim P.V., Yap Y.Y., Pua K.C., Kamatani N., Nakamura Y., Sam C.K., Khoo A.S., Malaysian N.P.C.S.G. and Ng C.C.
    • Journal Title

      Int J Cancer

      Volume: 136 Pages: 678-687

    • DOI

      10.1002/ijc.29035

    • Peer Reviewed
  • [Journal Article] Syndecan-1 responsive microRNA-126 and 149 regulate cell proliferation in prostate cancer2015

    • Author(s)
      Fujii, T., Shimada K., Tatsumi Y., Fujimoto K. and Konishi N.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 456 Pages: 183-189

    • DOI

      10.1016/j.bbrc.2014.11.056

    • Peer Reviewed
  • [Journal Article] Cigarette smoke inhalation and risk of lung cancer : a case-control study in a large Japanese population2015

    • Author(s)
      Fukumoto, K., Ito H., Matsuo K., Tanaka H., Yokoi K., Tajima K. and Takezaki T.
    • Journal Title

      Eur J Cancer Prev

      Volume: 24 Issue: 3 Pages: 195-200

    • DOI

      10.1097/CEJ.0000000000000034

    • Peer Reviewed
  • [Journal Article] Fine-Scale Mapping of the 5q11.2 Breast Cancer Locus Reveals at Least Three Independent Risk Variants Regulating MAP3K12015

    • Author(s)
      Glubb, D.M., Maranian M.J., Michailidou K., Pooley K.A., Meyer K.B., Kar S., Carlebur S., O'Reilly M., Betts J.A., Hillman K.M., Kaufmann S., Beesley J., Hopper J.L., Southey M.C., Apicella C., Schmidt M.K., Matsuo K., Ito H., Iwata H., Tanaka H., et al.
    • Journal Title

      Am J Hum Genet

      Volume: 96 Pages: 5-20

    • DOI

      10.1016/j.ajhg.2014.11.009

    • Peer Reviewed
  • [Journal Article] Gastric cancer in young vs old Romanian patients : immunoprofile with emphasis on maspin and mena protein reactivity2015

    • Author(s)
      Gurzu, S., Kadar Z., Sugimura H., Bara T., Bara T., Jr., Halmaciu I. and Jung I.
    • Journal Title

      APMIS

      Volume: 123 Pages: 223-233

    • DOI

      10.1111/apm.12347

    • Peer Reviewed
  • [Journal Article] Factors Associated With Non-participation in a Face-to-Face Second Survey Conducted 5 Years After the Baseline Survey2015

    • Author(s)
      Hara, M., Shimanoe C., Otsuka Y., Nishida Y., Nanri H., Horita M., Yasukata J., Miyoshi N., Yamada Y., Higaki Y. and Tanaka K.
    • Journal Title

      J Epidemiol

      Volume: 25 Pages: 117-125

    • DOI

      10.2188/jea.JE20140116

    • Peer Reviewed
  • [Journal Article] Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci2015

    • Author(s)
      He, M., Xu M., Zhang B., Liang J., Chen P., Lee J.Y., Kubo M., A., Li H., Yang X., Dai J., Liang L., Gui L., Qi Q., Huang J., Okada Y., Takeuchi F., Tanaka T., Yamamoto K., Yokota M., Kato N., et al.
    • Journal Title

      Hum Mol Genet

      Volume: 24 Pages: 1791-1800

    • DOI

      10.1093/hmg/ddu583

    • Peer Reviewed
  • [Journal Article] A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese2015

    • Author(s)
      Hirokawa, M., Morita H., Tajima T., Takahashi A., Ashikawa K., Miya F., Shigemizu D., Ozaki K., Sakata Y., Nakatani D., Suna S., Imai Y., Tanaka T., Tsunoda T., Matsuda K., Kadowaki T., Nakamura Y., Nagai R., Komuro I. and Kubo M.
    • Journal Title

      Eur J Hum Genet

      Volume: 23 Pages: 374-380

    • DOI

      10.1038/ejhg.2014.110

    • Peer Reviewed
  • [Journal Article] Low FOXA1 expression predicts good response to neo-adjuvant chemotherapy resulting in good outcomes for luminal HER2-negative breast cancer cases2015

    • Author(s)
      Horimoto, Y., Arakawa A., Harada-Shoji N., Sonoue H., Yoshida Y., Himuro T., Igari F., Tokuda E., Mamat O., Tanabe M., Hino O. and Saito M.
    • Journal Title

      Br J Cancer

      Volume: 112 Pages: 345-351

    • DOI

      10.1038/bjc.2014.595

    • Peer Reviewed
  • [Journal Article] Genome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians2015

    • Author(s)
      Hwang, J.Y., Sim X., Wu Y., Liang J., Tabara Y., Hu C., Hara K., Takeuchi F., Ong R.T., Ohkubo T., Kim Y.J., Zhang R., Yamauchi T., Katsuya T., Umemura S., Maeda S., Kita Y., Takashima N., Osawa H., Kato N., et al.
    • Journal Title

      Diabetes

      Volume: 64 Pages: 291-298

    • DOI

      10.2337/db14-0563

    • Peer Reviewed
  • [Journal Article] Circulating Pigment Epithelium-derived Factor (PEDF) Is Associated with Pathological Grade of Prostate Cancer2015

    • Author(s)
      Ide, H., Yamagishi S., Lu Y., Sakamaki K., Nakajima A., Horiuchi A., Kitamura K., Hisasue S., Muto S., Yamaguchi R. and Horie S.
    • Journal Title

      Anticancer Res

      Volume: 35 Pages: 1703-1708

    • Peer Reviewed
  • [Journal Article] B-RAF mutation and accumulated gene methylation in aberrant crypt foci (ACF), sessile serrated adenoma/polyp (SSA/P) and cancer in SSA/P2015

    • Author(s)
      Inoue, A., Okamoto K., Fujino Y., Nakagawa T., Muguruma N., Sannomiya K., Mitsui Y., Takaoka T., Kitamura S., Miyamoto H., Okahisa T., Fujimori T., Imoto I. and Takayama T.
    • Journal Title

      Br J Cancer

      Volume: 112 Pages: 403-412

    • DOI

      10.1038/bjc.2014.545

    • Peer Reviewed
  • [Journal Article] Establishment of Tsc2-deficient rat embryonic stem cells2015

    • Author(s)
      Ito, Y., Kawano H., Kanai F., Nakamura E., Tada N., Takai S., Horie S., Arai H., Kobayashi T. and Hino O.
    • Journal Title

      Int J Oncol

      Volume: 46 Pages: 1944-1952

    • DOI

      10.3892/ijo.2015.2913

    • Peer Reviewed
  • [Journal Article] Comparison of plasma levels of nutrient-related biomarkers among Japanese populations in Tokyo, Japan, Sao Paulo, Brazil, and Hawaii, USA2015

    • Author(s)
      Iwasaki, M., Franke A.A., Hamada G.S., Miyajima N.T., Sharma S., Ishihara J., Takachi R., Tsugane S. and Le Marchand L.
    • Journal Title

      Eur J Cancer Prev

      Volume: 24 Pages: 155-161

    • DOI

      10.1097/CEJ.0000000000000136

    • Peer Reviewed
  • [Journal Article] Comparison of plasma levels of obesity-related biomarkers among Japanese populations in Tokyo, Japan, Sao Paulo, Brazil, and Hawaii, USA2015

    • Author(s)
      Iwasaki, M., Le Marchand L., Franke A.A., Hamada G.S., Miyajima N.T., Sharma S., Yamaji T. and Tsugane S.
    • Journal Title

      Eur J Cancer Prev

    • DOI

      10.1097/CEJ.0000000000000123

    • Description
      Epub ahead of print
    • Peer Reviewed
  • [Journal Article] EVpedia : a community web portal for extracellular vesicles research2015

    • Author(s)
      Kim, D.K., Lee J., Kim S.R., Choi D.S., Yoon Y.J., Kim J.H., Go G., Nhung D., Hong K., Jang S.C., Kim S.H., Park K.S., Kim O.Y., Park H.T., Seo J.H., Aikawa E., Baj-Krzyworzeka M., van Balkom B.W., Tahara H., Youn H., et al.
    • Journal Title

      Bioinformatics

      Volume: 31 Pages: 933-939

    • DOI

      10.1093/bioinformatics/btu741

    • Peer Reviewed
  • [Journal Article] Cytological Features of a Variant NUT Midline Carcinoma of the Lung Harboring the NSD3-NUT Fusion Gene : A Case Report and Literature Review2015

    • Author(s)
      Kuroda, S., Suzuki S., Kurita A., Muraki M., Aoshima Y., Tanioka F. and Sugimura H.
    • Journal Title

      Case Rep Pathol

      Volume: 2015 Pages: 572951

    • DOI

      10.1155/2015/572951

    • Peer Reviewed
  • [Journal Article] Genome-wide association study identified SNP on 15q24 associated with bladder cancer risk in Japanese population2015

    • Author(s)
      Matsuda, K., Takahashi A., Obara W., Nasu Y., Inoue K., Tamura K., Yamasaki I., Naya Y., Tanikawa C., Namiki M., Tomita Y., Nishiyama H., Kohri K., Deguchi T., Nakagawa M., Yokoyama M., Miki T., Kumon H., Fujioka T., Kubo M., et al.
    • Journal Title

      Hum Mol Genet

      Volume: 24 Pages: 1177-1184

    • DOI

      10.1093/hmg/ddu512

    • Peer Reviewed
  • [Journal Article] Serologically Determined Gastric Mucosal Condition Is a Predictive Factor for Osteoporosis in Japanese Men2015

    • Author(s)
      Mizuno, S., Matsui D., Watanabe I., Ozaki E., Kuriyama N. and Watanabe Y.
    • Journal Title

      Dig Dis Sci

    • DOI

      10.1007/s10620-015-3576-1

    • Description
      Epub ahead of print
    • Peer Reviewed
  • [Journal Article] Validity of the food frequency questionnaire in a population with high alcohol consumption in Japan2015

    • Author(s)
      Nakahata, T.N., Takada N.A., Imaeda N., Goto C., Kuwabara H.K., Niimura H., Arai H., Yoshita Y. and Takezaki T.K.
    • Journal Title

      Asia Pac J Clin Nutr

    • Description
      in press
    • Peer Reviewed
  • [Journal Article] Dietary Patterns and Serum Gamma-Glutamyl Transferase in Japanese Men and Women2015

    • Author(s)
      Nanri, H., Hara M., Nishida Y., Shimanoe C., Nakamura K., Higaki Y., Imaizumi T., Taguchi N., Sakamoto T., Horita M., Shinchi K., Kokaze A. and Tanaka K.
    • Journal Title

      J Epidemiol

    • DOI

      10.2188/jea.JE20140158

    • Description
      in press
    • Peer Reviewed
  • [Journal Article] CD44-expressing undifferentiated carcinoma with rhabdoid features of the pancreas : Molecular analysis of aggressive invasion and metastasis2015

    • Author(s)
      Ohmoto, T., Yoshitani N., Nishitsuji K., Takayama T., Yanagisawa Y., Takeya M. and Sakashita N.
    • Journal Title

      Pathol Int

    • DOI

      10.1111/pin.12283

    • Description
      Epub ahead of print
    • Peer Reviewed
  • [Journal Article] Peretinoin after curative therapy of hepatitis C-related hepatocellular carcinoma : a randomized double-blind placebo-controlled study2015

    • Author(s)
      Okita, K., Izumi N., Matsui O., Tanaka K., Kaneko S., Moriwaki H., Ikeda K., Osaki Y., Numata K., Nakachi K., Kokudo N., Imanaka K., Nishiguchi S., Okusaka T., Nishigaki Y., Shiomi S., Kudo M., Ido K., Karino Y., Hayashi N., et al.
    • Journal Title

      J Gastroenterol

      Volume: 50 Pages: 191-202

    • DOI

      10.1007/s00535-014-0956-9

    • Peer Reviewed
  • [Journal Article] Cotyledonoid dissecting leiomyoma of the uterus : report of two cases2015

    • Author(s)
      Saeki, H., Suzuki C., Yamasaki S., Hashizume A., Izumi H., Suzuki F., Ishi K., Nojima M. and Hino O.
    • Journal Title

      Arch Gynecol Obstet

      Volume: 291 Pages: 357-361

    • DOI

      10.1007/s00404-014-3406-2

    • Peer Reviewed
  • [Journal Article] Association between endometriosis and the interleukin 1A (IL1A) locus2015

    • Author(s)
      Sapkota, Y., Low S.K., Attia J., Gordon S.D., Henders A.K., Holliday E.G., MacGregor S., Martin N.G., McEvoy M., Morris A.P., Takahashi A., Scott R.J., Kubo M., Zondervan K.T., Montgomery G.W. and Nyholt D.R.
    • Journal Title

      Hum Reprod

      Volume: 30 Pages: 239-248

    • DOI

      10.1093/humrep/deu267

    • Peer Reviewed
  • [Journal Article] Werner Syndrome-specific induced pluripotent stem cells : recovery of telomere function by reprogramming2015

    • Author(s)
      Shimamoto, A., Yokote K. and Tahara H.
    • Journal Title

      Front Genet

      Volume: 6 Pages: 10

    • DOI

      10.3389/fgene.2015.00010

    • Peer Reviewed
  • [Journal Article] Perceived stress and coping strategies in relation to body mass index : cross-sectional study of 12,045 Japanese men and women2015

    • Author(s)
      Shimanoe, C., Hara M., Nishida Y., Nanri H., Otsuka Y., Nakamura K., Higaki Y., Imaizumi T., Taguchi N., Sakamoto T., Horita M., Shinchi K. and Tanaka K.
    • Journal Title

      PLoS One

      Volume: 10 Pages: e0118105

    • DOI

      10.1371/journal.pone.0118105

    • Peer Reviewed
  • [Journal Article] The oncological outcome and validation of Japan Cancer of the Prostate Risk Assessment score among men treated with primary androgen-deprivation therapy2015

    • Author(s)
      Shiota, M., Yokomizo A., Takeuchi A., Imada K., Kiyoshima K., Inokuchi J., Tatsugami K. and Naito S.
    • Journal Title

      J Cancer Res Clin Oncol

      Volume: 141 Pages: 495-503

    • DOI

      10.1007/s00432-014-1828-7

    • Peer Reviewed
  • [Journal Article] Associations between polymorphisms of interleukin-6 and related cytokine genes and serum liver damage markers : a cross-sectional study in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study2015

    • Author(s)
      Sugimoto, Y., Wakai K., Nakagawa H., Suma S., Sasakabe T., Sakamoto T., Takashima N., Suzuki S., Ogawa S., Ohnaka K., Kuriyama N., Arisawa K., Mikami H., Kubo M., Hosono S., Hamajima N., Tanaka H. and J-Micc Study Group
    • Journal Title

      Gene

      Volume: 557 Pages: 158-162

    • DOI

      10.1016/j.gene.2014.12.025

    • Peer Reviewed
  • [Journal Article] Rheb actvation disrupts spine synapse formation through accumulation of syntenin in tuberous sclerosis complex2015

    • Author(s)
      Sugiura H., Y.S., Katsurabayashi S., Kawano H., Endo K., Takasaki K., Iwasaki K., Ichikawa M., Kobayashi T., Hino O. and Yamagata K.
    • Journal Title

      Nature Communications

      Volume: 6 Pages: 6842

    • DOI

      10.1038/ncomms7842

    • Peer Reviewed
  • [Journal Article] Urethral toxicity after LDR brachytherapy : experience in Japan2015

    • Author(s)
      Tanaka, N., Asakawa I., Hasegawa M. and Fujimoto K.
    • Journal Title

      Brachytherapy

      Volume: 14 Pages: 131-135

    • DOI

      10.1016/j.brachy.2014.09.009

    • Peer Reviewed
  • [Journal Article] A potential function for neuronal exosomes : sequestering intracerebral amyloid-beta peptide2015

    • Author(s)
      Yuyama, K. Sun H., Usuki S. Sakai S. Hanamatsu H., Mioka T. Kimura N. Okada N. Tahara H. Furukawa J. Fujitani N. Shinohara Y. and Igarashi Y.
    • Journal Title

      FEBS Lett

      Volume: 589 Pages: 84-88

    • DOI

      10.1016/j.febslet.2014.11.027

    • Peer Reviewed
  • [Journal Article] Clinical outcomes of a novel therapeutic vaccine with Tax peptide-pulsed dendritic cells for adult T cell leukaemia/lymphoma in a pilot study.2015

    • Author(s)
      Suehiro, Y., Hasegawa, A., Iino, T., Sasada, A., Watanabe, N., Matsuoka, M., Takamori, A., Tanosaki, R., Utsunomiya, A., Choi, I., Fukuda, T., Miura, O., Takaishi, S., Teshima, T., Akashi, K., Kannagi, M., Uike, N., Okamura, J.
    • Journal Title

      British journal of haematology

    • DOI

      10.1111/bjh.13302

    • Description
      印刷中
    • Peer Reviewed
  • [Journal Article] Involvement of double-stranded RNA-dependent protein kinase and antisenseviral RNA in the constitutive NFkappaB activation in adult T-cell leukemia/lymphoma cells2015

    • Author(s)
      Kinpara, S., Ito, S., Takahata, T., Saitoh, Y., Hasegawa, A., Kijiyama, M., Utsunomiya, A., Masuda, M., Miyazaki, Y., Matsuoka, M., Nakamura, M., Yamaoka, S., Masuda, T., Kannagi, M.
    • Journal Title

      Leukemia

    • DOI

      10.1038/leu.2015.1

    • Description
      印刷中
    • Peer Reviewed
  • [Journal Article] Fatal reactivation of hepatitis B virus infection in a patient with adult T-cell leukemia-lymphoma receiving the anti-CC chemokine receptor 4 antibody mogamulizumab2015

    • Author(s)
      Ifuku, H., Kusumoto, S., Tanaka, Y., Totani, H., Ishida, T., Okada, M., Murakami, S., Mizokami, M., Ueda, R. & lida, S.
    • Journal Title

      Hepatology research : the official journal of the Japan Society of Hepatology

    • DOI

      10.1111/hepr.12513

    • Description
      印刷中
    • Peer Reviewed
  • [Journal Article] Dose-intensified chemotherapy alone or in combination with mogamulizumab in newly diagnosed aggressive adult T-cell leukaemia-lymphoma : a randomized phase II study2015

    • Author(s)
      Ishida, T., Jo, T., Takemoto, S., Suzushima, H., Uozumi, K., Yamamoto, K., Uike, N., Saburi, Y., Nosaka, K., Utsunomiya, A., Tobinai, K., Fujiwara, H., Ishitsuka, K., Yoshida, S., Taira, N., Moriuchi, Y., Imada, K., Miyamoto, T., Akinaga, S., Tomonaga, M. & Ueda, R.
    • Journal Title

      British journal of haematology

    • DOI

      10.1111/bjh.13338

    • Description
      印刷中
    • Peer Reviewed
  • [Journal Article] Prognostic significance of tryptophan catabolism in adult T-cell leukemia/lymphoma2015

    • Author(s)
      Masaki, A., Ishida, T., Maeda, Y., Suzuki, S., Ito, A., Takino, H., Ogura, H., Totani, H., Yoshida, T., Kinoshita, S., Narita, T., Ri, M., Kusumoto, S., Inagaki, A., Komatsu, H., Niimi, A., Ueda, R., Utsunomiya, A., Inagaki, H. & Iida, S.
    • Journal Title

      Clinical cancer research : an official journal of the American Association for Cancer Research

    • DOI

      10.1158/1078-0432.CCR-14-2275

    • Description
      印刷中
    • Peer Reviewed
  • [Journal Article] CD30-positive primary bone marrow lymphoma mimicking Hodgkin lymphoma2015

    • Author(s)
      Suzuki T, Kusumoto S, Masaki A, Ishida T, Inagaki H, Iida S, Mori F
    • Journal Title

      Int J Hematol

      Volume: 101 Issue: 2 Pages: 109-11

    • DOI

      10.1007/s12185-014-1714-8

    • Peer Reviewed
  • [Journal Article] Reactivation of hepatitis B virus (HBV) infection in adult T-cell leukemia-lymphoma patients with resolved HBV infection following systemic chemotherapy2015

    • Author(s)
      Totani, H., Kusumoto, S., Ishida, T., Masuda, A., Yoshida, T., Ito, A., Ri, M., Komatsu, H., Murakami, S., Mizokami, M., Ueda, R., Niimi, A., Inagaki, H., Tanaka, Y. & Iida, S.
    • Journal Title

      International journal of hematology

      Volume: 101 Pages: 398-404

    • DOI

      10.1007/s12185-015-1750-z

    • Peer Reviewed
  • [Journal Article] TCFl and LEFl act as T-cell intrinsic HTLV-1 antagonists by targeting Tax2015

    • Author(s)
      Ma G, Yasunaga J-I, Akari H, Matsuoka M
    • Journal Title

      Proc. Natl. Acad. Sci. U.S.A.

      Volume: 112 Pages: 2216-2221

    • DOI

      10.1073/pnas.1419198112

    • Peer Reviewed
  • [Journal Article] Human T-cell leukemia virus type 1 Tax oncoprotein represses the expression of the BCL11B tumor suppressor in T-cells2015

    • Author(s)
      Takachi T, Takahashi M, Takahashi-Yoshita M, Higuchi M, Obata M, Mishima Y, Okuda S, Tanaka Y, Matsuoka M, Saitoh A, Green P, Fujii M
    • Journal Title

      Cancer Sci

    • DOI

      10.1111/cas.12618

    • Description
      in press
    • Peer Reviewed
  • [Journal Article] Re-evaluation of screening of plasma positive for human T-cell leukemia virus type 1 using a luciferase immunoprecipitation system in blood donors2015

    • Author(s)
      Furuta RA, Ma G, Matsuoka M, Otani S, Matsukura H, Hirayama F
    • Journal Title

      Transfusion

    • DOI

      10.1111/trf.12911

    • Description
      in press
    • Peer Reviewed
  • [Journal Article] Visualization of HTLV-1-specific cytotoxic T lymphocytes in the spinal cords of patients with HTLV-1-associated myelopathy/tropical spastic paraparesis2015

    • Author(s)
      Matsuura E, Kubota R, Tanaka Y, Takashima H, Izumo S
    • Journal Title

      J Neuropathol Exp Neurol

      Volume: 74 Issue: 1 Pages: 2-14

    • DOI

      10.1097/NEN.0000000000000141

    • Peer Reviewed
  • [Journal Article] Separate cellular localizations of human T-lymphotropic virus 1 (HTLV-1) Env and glucose transporter type 1 (GLUT1) are required for HTLV-1 Env-mediated fusion and infection2015

    • Author(s)
      Maeda Y, Terasawa H, Tanaka Y, Mitsuura C, Nakashima K, Yusa K, Harada S
    • Journal Title

      J Virol

      Volume: 89 Issue: 1 Pages: 502-11

    • DOI

      10.1128/JVI.02686-14

    • Peer Reviewed
  • [Journal Article] Mogamulizumab, an anti-CCR4 antibody, targets human T-lymphotropic virus type 1-infected CD8+ and CD4+ T cells to treat associated myelopathy2015

    • Author(s)
      Yamauchi J, Coler-Reilly A, Sato T, Araya N, Yagishita N, Ando H, Kunitomo Y, Takahashi K, Tanaka Y, Shibagaki Y, Nishioka K, Nakajima T, Hasegawa Y, Utsunomiya A, Kimura K, Yamano Y
    • Journal Title

      J Infect Dis

      Volume: 211 Issue: 2 Pages: 238-48

    • DOI

      10.1093/infdis/jiu438

    • Peer Reviewed
  • [Journal Article] Advanced HTLV-1 carriers and early-stage indolent ATLs are indistinguishable based on CADM1 positivity in flow cytometry2015

    • Author(s)
      Kobayashi S, Watanabe E, Ishigaki T, Ohno N, Yuji K, Nakano K, Yamochi T, Watanabe N, Tojo A, Watanabe T, Uchimaru K
    • Journal Title

      Cancer Sci

    • DOI

      10.1111/cas.12639

    • Description
      Epub ahead of print
    • Peer Reviewed
  • [Journal Article] Identification of TL-Oml, an ATL Cell Line, as a Reference Material for Human T-Lymphotropic Virus 1 Quantitative PCR2015

    • Author(s)
      Kuramitsu M, Okuma K, Yamagishi M, Yamochi T, Firouzi S, Momose H, Mizukami T, Takizawa K, Araki K, Sugamura K, Yamaguchi K, Watanabe T, Hamaguchi I
    • Journal Title

      J Clin Microbiol

      Volume: 53 Issue: 2 Pages: 587-596

    • DOI

      10.1128/JCM.02254-14

    • Peer Reviewed
  • [Journal Article] Epigenetic Heterogeneity in HIV-1 Latency Establishment2015

    • Author(s)
      Matsuda Y, Kobayashi-Ishihara M, Fujikawa D, Ishida T, Watanabe T, Yamagishi M
    • Journal Title

      Sci Rep

      Volume: 5 Pages: 7701

    • DOI

      10.1038/srep07701

    • Peer Reviewed
  • [Journal Article] SMK-17, a MEK1/2-specific inhibitor, selectively induces apoptosis in β-catenin-mutated tumors.2015

    • Author(s)
      Kiga M, Nakayama A, Shikata Y, Sasazawa Y, Murakami R, Nakanishi T, Tashiro E, Imoto M.
    • Journal Title

      Sci Rep.

      Volume: 5 Pages: 8155

    • DOI

      10.1038/srep08155

    • Peer Reviewed
  • [Journal Article] Basal expression of insulin-like growth factor l receptor determines intrinsic resistance of cancer cells to a phosphatidylinositol 3-kinase inhibitor ZSTK4742015

    • Author(s)
      Isoyama S, Kajiwara G, Tamaki N, Okamura M, Yoshimi H, Nakamura N, Kawamura K, Nishimura Y, Namatame N, Yamori T, Dan S
    • Journal Title

      Cancer Sci

      Volume: 106 Issue: 2 Pages: 171-178

    • DOI

      10.1111/cas.12582

    • Peer Reviewed
  • [Journal Article] Design, synthesis and structure-activity relationships of 1-ethylpyrazole-3-carboxamide as novel HIF-1 inhibitors2015

    • Author(s)
      Yasuda Y, Arakawa T, Nawata Y, Shimada S, Oishi S, Fujii N, Nishimura S, Hattori A, Kakeya H
    • Journal Title

      Bioorg. Med. Chem.

      Volume: 23 Pages: 1776-1787

    • DOI

      10.1016/j.bmc.2015.02.038

    • Peer Reviewed
  • [Journal Article] Association of microRNA-31-5p with clinical efficacy of anti-EGFR therapy in patients with metastatic colorectal cancer2015

    • Author(s)
      Igarashi H, Kurihara H, Mitsuhashi K, Ito M, Okuda H, Kanno S, Naito T, Yoshii S, Takahashi H, Kusumi T, Hasegawa T, Sukawa Y, Adachi Y, Okita K, Hirata K, Imamura Y, Baba Y, Imai K, Suzuki H, Yamamoto H, Nosho K, Shinomura Y
    • Journal Title

      Ann Surg Oncol

    • DOI

      10.1245/s10434-014-4264-7

    • Description
      Epub ahead of print
    • Peer Reviewed
  • [Journal Article] Mesenchymal stem cells cancel azoxymethane-induced tumor initiation2014

    • Author(s)
      Nasuno M, Arimura Y, Nagaishi K, Isshiki H, Onodera K, Nakagaki S, Watanabe S, Idogawa M, Yamashita K, Naishiro Y, Adachi Y, Suzuki H, Fujimiya M, Imai K, Shinomura Y
    • Journal Title

      STEM CELLS

      Volume: 32 Issue: 4 Pages: 913-25

    • DOI

      10.1002/stem.1594

    • Peer Reviewed
  • [Journal Article] MicroRNA-31 expression in relation to BRAF mutation, CpG island methylation and colorectal continuum in serrated lesions2014

    • Author(s)
      Ito M, Mitsuhashi K, Igarashi H, Nosho K, Naito T, Yoshii S, Takahashi H, Fujita M, Sukawa Y, Yamamoto E, Takahashi T, Adachi Y, Nojima M, Sasaki Y, Tokino T, Baba Y, Maruyama R, Suzuki H, Imai K, Yamamoto H, Shinomura Y
    • Journal Title

      Int J Cancer

      Volume: 135 Issue: 11 Pages: 2507-15

    • DOI

      10.1002/ijc.28920

    • Peer Reviewed
  • [Journal Article] The effect of IGF-I receptor blockade for human esophageal squamous cell carcinoma and adenocarcinoma2014

    • Author(s)
      Adachi Y, Ohashi H, Imsumran A, Yamamoto H, Matsunaga Y, Taniguchi H, Nosho K, Suzuki H, Sasaki Y, Arimura Y, Carbone DP, Imai K, Shinomura Y
    • Journal Title

      Tumor Biol

      Volume: 35 Issue: 2 Pages: 973-85

    • DOI

      10.1007/s13277-013-1131-2

    • Peer Reviewed
  • [Journal Article] Analysis of DNA methylation in bowel lavage fluid for detection of colorectal cancer2014

    • Author(s)
      Harada T, Yamamoto E, Yamano H, Nojima M, Maruyama R, Kumegawa K, Ashida M, Yoshikawa K, Kimura T, Harada E, Takagi R, Tanaka Y, Aoki H, Nishizono M, Nakaoka M, Tuyada A, Niinuma T, Kai M, Shimoda K, Shinomura Y, Sugai T, Imai K, Suzuki H
    • Journal Title

      Cancer Prevention Research (Philadelphia, Pa.)

      Volume: 7 Issue: 10 Pages: 1002-10

    • DOI

      10.1158/1940-6207.CAPR-14-0162

    • Peer Reviewed
  • [Journal Article] Overview and Future prospect of “Promotion plan for the platform of human resource development for cancer”2014

    • Author(s)
      Imai K.
    • Journal Title

      Juntendo Medical Journal

      Volume: 60 Issue: 3 Pages: 234-237

    • Peer Reviewed
  • [Journal Article] IGF2 differentially methylated region hypomethylation in relation to pathological and molecular features of serrated lesions2014

    • Author(s)
      Naito T, Nosho K, Ito M, Igarashi H, Mitsuhashi K, Yoshii S, Aoki H, Nomura M, Sukawa Y, Yamamoto E, Adachi Y, Takahashi H, Hosokawa M, Fujita M, Takenouchi T, Maruyama R, Suzuki H, Baba Y, Imai K, Yamamoto H, Ogino S, Shinomura Y
    • Journal Title

      World J Gastroenterol

      Volume: 20 Issue: 29 Pages: 10050-61

    • DOI

      10.3748/wjg.v20.i29.10050

    • Peer Reviewed
  • [Journal Article] DNA synthesis inhibitors for the treatment of gastrointestinal cancer2014

    • Author(s)
      Yasui H, Tsurita G, Imai K
    • Journal Title

      Expert Opin Pharmacother

      Volume: 15 Issue: 16 Pages: 2361-72

    • DOI

      10.1517/14656566.2014.958074

    • Peer Reviewed
  • [Journal Article] The Use of Bone Marrow Stromal Cells (Bone Marrow-Derived Multipotent Mesenchymal Stromal Cells) for Alveolar Bone Tissue Engineering : Basic Science to Clinical Translation2014

    • Author(s)
      Kagami H, Agata H, Inoue M, Asahina I, Tojo A, Yamashita N, Imai K
    • Journal Title

      Tissue Engineering Part B : Reviews

      Volume: 20 Issue: 3 Pages: 229-232

    • DOI

      10.1089/ten.TEB.2013.0578

    • Peer Reviewed
  • [Journal Article] Association of microRNA-31-5p with clinical efficacy of anti-EGFR therapy in patients with metastatic colorectal cancer2014

    • Author(s)
      Igarashi H, Kurihara H, Mitsuhashi K, Ito M, Okuda H, Kanno S, Naito T, Yoshii S, Takahashi H, Kusumi T, Hasegawa T, Sukawa Y, Adachi Y, Okita K, Hirata K, Imamura Y, Baba Y, Imai K, Suzuki H, Yamamoto H, Nosho K, Shinomura Y
    • Journal Title

      Annals of Surgical Oncology

    • Description
      Epub ahead of print
    • Peer Reviewed
  • [Journal Article] 総説 橋渡し研究の展開と我が国の医療2014

    • Author(s)
      今井浩三
    • Journal Title

      東京都病院薬剤師会雑誌

      Volume: 63 Issue: 2 Pages: 5-8

    • Peer Reviewed
  • [Journal Article] 人口動態に基づいた日本医療の未来予測-高齢多死社会の到来, 特集「超高齢者に対する外科治療の問題点」2014

    • Author(s)
      湯地晃一郎, 井元清哉, 山口類, 宮野悟, 上昌広, 今井浩三
    • Journal Title

      南江堂臨床雑誌「外科」

      Volume: 76 Issue: 5 Pages: 457-463

    • Peer Reviewed
  • [Journal Article] 大規模コホートを用いた大腸癌のノンコーディングRNA発現異常と生活習慣の分子疫学的解析2014

    • Author(s)
      能正勝彦, 五十嵐央祥, 伊藤美樹, 三橋慧, 栗原弘義, 菅野伸一, 内藤崇史, 須河安恭敬, 松永康孝, 足立靖, 野島正寛, 今井浩三, 丸山玲緒, 鈴木拓, 山本博幸, 篠村恭久
    • Journal Title

      日本癌病態治療研究会誌

      Volume: 20 Issue: 1 Pages: 60-63

    • Peer Reviewed
  • [Journal Article] がんエピゲノム異常を理解し、応用し、そして制御するために2014

    • Author(s)
      鈴木拓, 今井浩三
    • Journal Title

      実験医学

      Volume: 32 Issue: 19 Pages: 3024-3029

    • Peer Reviewed
  • [Journal Article] Generation and analysis of serine protease inhibitor Kazal type 3-cre driver mice2014

    • Author(s)
      Sakata, K., Ohmuraya, M., Araki, K., Suzuki, C., Ida, S., Hashimoto, D., Wang, J., Uchiyama, Y., Baba, H. and Yamamura, K.
    • Journal Title

      Exp. Anim.

      Volume: 63 Pages: 45-53

    • Peer Reviewed
  • [Journal Article] Autophagy regulation in the pancreatic acinar cells is independent of epidermal growth factor receptor signaling2014

    • Author(s)
      Ozaki, N., Fukuchi, Y., Tomiyoshi, S., Ueharal, H., Ida, S., Wang, J., Kimi Araki, K., Sibilia, M., Baba, H., Yamamura, K. and Ohmuraya, M
    • Journal Title

      Biochem. Biophysic. Res. Comm.

      Volume: 446 Pages: 224-230

    • DOI

      10.1016/j.bbrc.2014.02.111

    • Peer Reviewed
  • [Journal Article] Low serum level of high-sensitivity C-reactive protein in a Japanese subject with MODY32014

    • Author(s)
      Ohki T, Utsu Y, Morita S, Karim M.F., Sato Y, Yoshizawa T, Yamamura K, Yamada K, Kasayama S, Yamagata K
    • Journal Title

      J. Diabetes Invest

      Volume: 5 Pages: 513-516

    • DOI

      10.1111/jdi.12237

    • Peer Reviewed
  • [Journal Article] Genetic analysis of the role of Alx4 in the coordination of lower body and external genitalia formation2014

    • Author(s)
      Matsumaru, D., Haraguchi, R., Moon, A.M., Satoh, Y., Nakagata, N., Yamamura, K., Takahashi, N., Kitazawa, S. and Yamada, G.
    • Journal Title

      Eur. J. Human Genet

      Volume: 22 Pages: 350-357

    • DOI

      10.1038/ejhg.2013.160

    • Peer Reviewed
  • [Journal Article] mTORCl controls the cell cycle of the earliest T-lineage-committed cells and its inactivation eradicates acute Iymphoblastic T-cell leukemia in mice2014

    • Author(s)
      Hoshii, T., Kasada, A., Hatakeyama, N., Ohtani, M., Tadokoro, Y., Naka, K., Ikenoue, T., Ikawa, T., Kawamoto, H., Araki, K., Yamamura, K., Matsuda, S. and Hirao, A.
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 111 Pages: 3805-3810

    • DOI

      10.1073/pnas.1320265111

    • Peer Reviewed
  • [Journal Article] Circulating AIM prevents hepatocellular carcinoma through complement activation2014

    • Author(s)
      Maehara, N., Arai, S., Mori, M., Iwamura, Y., Kurokawa, J., Kai, T., Kusunoki, S., Taniguchi, K., Ikeda, K., Ohara, O., Yamamura, K. and Miyazaki, T.
    • Journal Title

      Cell Report

      Volume: 9 Pages: 1-14

    • DOI

      10.1016/j.celrep.2014.08.058

    • Peer Reviewed
  • [Journal Article] Disruption of dystonin protein containing actin-binding domain cause dystonia musculorum in mice2014

    • Author(s)
      Horie, M., Watanabe, K., Bepari, A.K., Nashimoto, J., Araki, K., Sano, H., Chiken, S., Nambu, A., Ono, K., Ikenaka, K., Kakita, A., Yamamura, K. and Takebayashi, H.
    • Journal Title

      Eur. J. Neurocsi

      Volume: 40 Pages: 3458-3471

    • DOI

      10.1111/ejn.12711

    • Peer Reviewed
  • [Journal Article] Circulating AIM as an indicator of liver damage and hepatocellular carcinoma in humans2014

    • Author(s)
      Yamazaki, T., Mori, M., Arai, S., Tateishi, R., Abe, M., Ban, M., Nishijima, A., Maeda, M., Asano, T., Kai, T., Izumino, K., Takahashi, J., Aoyama, K., Harada, S., Takebayashi, T., Gunji, T, Ohnishi, S., Seto, S., Yoshida, Y., Hiasa, Y., Koike, K., Yamamura, K., Inoue, K. & Miyazaki, T.
    • Journal Title

      Plos One

      Volume: 9 Pages: e109123

    • DOI

      10.1371/journal.pone.0109123

    • Peer Reviewed
  • [Journal Article] Database for exchangeable gene trap clones : Pathway and gene ontology analysis of exchangeable genetrap clone mouse lines2014

    • Author(s)
      Araki, M., Nakahara, M., Muta, M., Itou, M., Yanai, C., Yamazoe, F., Miyake, M., Morita, A., Araki, M., Okamoto, Y., Nakagata, M., Yoshinobu, K., Yamamura, K. and Araki, K.
    • Journal Title

      Develop. Growth Differ

      Volume: 56 Pages: 161-174

    • DOI

      10.1111/dgd.12116

    • Peer Reviewed
  • [Journal Article] Screening Methods to Identify TALEN-Mediated Knockout Mice2014

    • Author(s)
      Nakagawa, Y., Yamamoto, T., Suzuki, K., Araki, K., Takeda, N., Ohmuraya, M. and Sakuma, T.
    • Journal Title

      Exp. Anim.

      Volume: 63 Pages: 79-84

    • Peer Reviewed
  • [Journal Article] Role of blood ribosomal protein S19 in coagulum resorption : a study using Gln137Glu-ribosomal protein S19 gene knock-in mouse2014

    • Author(s)
      Chen, J., Fujino, R., Zhao, R., Semba, U., Araki, K. and Yamamoto, T.
    • Journal Title

      Pathol. Int.

      Volume: 64 Pages: 543-550

    • DOI

      10.1111/pin.12208

    • Peer Reviewed
  • [Journal Article] Conformational Change in Transfer RNA Is an Early Indicator of Acute Cellular Damage2014

    • Author(s)
      Mishima, E., Inoue, C., Saigusa, D., Inoue, R., Ito, K., Suzuki, Y., Jinno, D., Tsukui, Y., Akamatsu, Y., Araki, M., Araki, K., Shimizu, R., Shinke, H., Suzuki, T., Takeuchi, Y., Shima, H., Akiyama, Y., Yamamura, K., et al.
    • Journal Title

      J. Am. Soc. Nephrol

      Volume: 25 Pages: 2316-2326

    • DOI

      10.1681/ASN.2013091001

    • Peer Reviewed
  • [Journal Article] Impaired degradation of WNK1 and WNK4 kinases causes PHAII in mutant KLHL3 knock-in mice2014

    • Author(s)
      Susa, K, Sohara, E, Rai, T, Zeniya, M, Mori, Y, Mori, T, Chiga, M, Nomura, N, Nishida, H, Takahashi, D, Isobe, K, Inoue, Y, Takeishi, K, Takeda, N, Sasaki, S, Uchida, S
    • Journal Title

      Hum Mol Genet

      Volume: 23 Pages: 5052-5060

    • DOI

      10.1093/hmg/ddu217

    • Peer Reviewed
  • [Journal Article] Novel retinoblastoma mutation abrogating the interaction to E2F2/3, but not E2F1, led to selective suppression of thyroid tumors2014

    • Author(s)
      Toki, H., Inoue, M., Minowa, O., Motegi, H., Saiki, Y., Wakana, S., Masuya, H., Gondo, Y., Shiroishi, T., Yao, R. & Noda, T.
    • Journal Title

      Cancer Sci

      Volume: 105 Pages: 1360-1368

    • DOI

      10.1111/cas.12495

    • Peer Reviewed
  • [Journal Article] Deficiency of Transcription Factor Brn4 Disrupts Cochlear Gap Junction Plaques in a Model of DFN3 Non-Syndromic Deafness2014

    • Author(s)
      Kidokoro Y, Karasawa K, Minowa O, Sugitani Y., Noda T, Ikeda K, Kamiya K.
    • Journal Title

      PLoS One

      Volume: 9 Issue: 9 Pages: e108216

    • DOI

      10.1371/journal.pone.0108216

    • Peer Reviewed
  • [Journal Article] Assembly of the cochlear gap junction macromolecular complex requires connexin 262014

    • Author(s)
      Kamiya K, Yum SW, Kurebayashi N, Muraki M, Ogawa K, Karasawa K, Miwa A, Guo X, Gotoh S, Sugitani Y., Yamanaka H, Ito-Kawashima S, Iizuka T, Sakurai T, Noda T, Minowa O, Ikeda K.
    • Journal Title

      J. Clin. Invest.

      Volume: 124 Issue: 4 Pages: 1598-1607

    • DOI

      10.1172/JCI67621

    • Peer Reviewed
  • [Journal Article] Identification of genomic locus responsible for experimentally induced testicular teratoma 1 (ettl) on mouse Chr 182014

    • Author(s)
      Miyazaki, T., Ikeda, Y., Kubo, I., Suganuma, S., Fujita, N., Itakura, M., Hayashi, T., Takabayashi, S., Katoh, H., Ohira, Y., Sato, M., Noguchi, M., Tokumoto, T.
    • Journal Title

      Mammalian Genome

      Volume: 25 Pages: 317-326

    • DOI

      10.1007/s00335-014-9529-8

    • Peer Reviewed
  • [Journal Article] Contemporary techniques for freezing mouse spermatozoa2014

    • Author(s)
      Guan, M., Bogani D., Marschall, S., Raspa M., Takeo, T., Nakagata, N., Taft, R. and Fray, M.
    • Journal Title

      Curr Protoc Mouse Biol

      Volume: 4 Issue: 3 Pages: 85-104

    • DOI

      10.1002/9780470942390.mo140065

    • Peer Reviewed
  • [Journal Article] In vitro fertilization in mice using the MBCD-GSH protocol2014

    • Author(s)
      Guan, M., Bogani, D., Marschall, S., Raspa, M., Takeo, T., Nakagata, N. and Fray, M.
    • Journal Title

      Curr Protoc Mouse Biol

      Volume: 4 Issue: 2 Pages: 67-83

    • DOI

      10.1002/9780470942390.mo140059

    • Peer Reviewed
  • [Journal Article] Transporting mouse embryos and germplasm as frozen or unfrozen materials2014

    • Author(s)
      Kenyon, J., Guan, M., Bogani, D., Marschall, S., Raspa, M., Pickard, A., Takeo, T., Nakagata, N. and Fray, M.
    • Journal Title

      Curr Protoc Mouse Biol

      Volume: 4 Issue: 2 Pages: 47-65

    • DOI

      10.1002/9780470942390.mo140064

    • Peer Reviewed
  • [Journal Article] Conservation of mouse models through embryo freezing2014

    • Author(s)
      Guan, M, Bogani, D, Marschall, S, Raspa, M, Takeo, T, Nakagata, N, Fray, M
    • Journal Title

      Curr Protoc Mouse Biol

      Volume: 4 Issue: 4 Pages: 205-227

    • DOI

      10.1002/9780470942390.mo140082

    • Peer Reviewed
  • [Journal Article] Rescue in vitro fertilization method for legacy stock of frozen mouse sperm2014

    • Author(s)
      Nakagata, N, Takeo, T, Fukumoto, K, Haruguchi, Y, Kondo, T, Takeshita, Y, Nakamuta, Y, Umeno, T, Tsuchiyama, S
    • Journal Title

      J Reprod Dev

      Volume: 60 Issue: 2 Pages: 168-171

    • Peer Reviewed
  • [Journal Article] Application of oocyte cryopreservation technology in TALEN-mediated mouse genome editing2014

    • Author(s)
      Nakagawa, Y., Sakuma, T., Nakagata, N., Yamasaki, S., Takeda, N., Ohmuraya, M. and Yamamoto, T.
    • Journal Title

      Exp Anim

      Volume: 63 Issue: 3 Pages: 349-355

    • Peer Reviewed
  • [Journal Article] Histological detection of catalytic ferrous iron with the selective turn-on fluorescent probe RhoNox-1 in a Fenton reaction-based rat renal carcinogenesis model2014

    • Author(s)
      Mukaide, T, Hatori, Y, Misawa, N, Funahashi, S, Jiang, L, Hirayama, T, Nagasawa, H and Toyokuni, S
    • Journal Title

      Free Radic Res

      Volume: 48 Pages: 990-995

    • DOI

      10.3109/10715762.2014.898844

    • Peer Reviewed
  • [Journal Article] Connective tissue growth factor and β-catenin constitute an autocrine loop for activation in rat sarcomatoid mesothelioma2014

    • Author(s)
      Jiang, L, Yamashita, Y, Chew, SH, AKatsuka, S, Ukai, S, Wang, S, Nagai, H, Okazaki, Y, Takahashi, T and Toyokuni, S
    • Journal Title

      J Pathol

      Volume: 233 Pages: 402-414

    • DOI

      10.1002/path.4377

    • Peer Reviewed
  • [Journal Article] Iron and thiols as two major players in carcinogenesis : friends or foes?2014

    • Author(s)
      Toyokuni, S.
    • Journal Title

      Front Pharmacol

      Volume: 5 Pages: 200

    • DOI

      10.3389/fphar.2014.00200

    • Peer Reviewed
  • [Journal Article] Hsc70 contributes to cancer cell survival by preventing RablA degradation under stress conditions2014

    • Author(s)
      Tanaka, M, Mun, S, Harada, A, Ohkawa, Y, Inagaki, A, Sano, S, Takahashi, K, Izumi, Y, Osada-Oka, M, Wanibuchi, H, Yamagata, M, Yukimura, T, Miura, K, Shiota, M, Iwao, H
    • Journal Title

      PLoS One

      Volume: 9 Pages: e96785

    • DOI

      10.1371/journal.pone.0096785

    • Peer Reviewed
  • [Journal Article] Inhibitory effect of raphanobrassica on Helicobacter pylori-induced gastritis in Mongolian gerbils2014

    • Author(s)
      Yamada, T, Wei, M, Toyoda, T, Yamano, S, Wanibuchi, H
    • Journal Title

      Food Chem Toxicol

      Volume: 70 Pages: 107-113

    • DOI

      10.1016/j.fct.2014.04.037

    • Peer Reviewed
  • [Journal Article] Genotoxicity and subacute toxicity studies of a new astaxanthin-containing Phaffia rhodozyma extract2014

    • Author(s)
      Tago, Y, Fujii, T, Wada, J, Kato, M, Wei, M, Wanibuchi, H, Kitano, M
    • Journal Title

      J Toxicol Sci

      Volume: 39 Pages: 373-382

    • Peer Reviewed
  • [Journal Article] Vascular endothelial growth factor mRNA levels as a biomarker for short-term N-butyl-N-(4-hydroxybutyl) nitrosamine-induced rat bladder carcinogenesis bioassay2014

    • Author(s)
      Wakui, S, Mutou, T, Takahashi, H, Ikegami, M, Wanibuchi, H, Fukushima, S
    • Journal Title

      J Appl Toxicol

      Volume: 35 Issue: 2 Pages: 181-190

    • DOI

      10.1002/jat.3021

    • Peer Reviewed
  • [Journal Article] Valerian inhibits rat hepatocarcinogenesis by activating GABA(A) receptor-mediated signaling2014

    • Author(s)
      Kakehashi, A, Kato, A, Ishii, N, Wei, M, Morimura, K, Fukushima, S, Wanibuchi, H
    • Journal Title

      PLoS One

      Volume: 9 Pages: e113610

    • DOI

      10.1371/journal.pone.0113610

    • Peer Reviewed
  • [Journal Article] Establishment of neutralizing rat monoclonal antibodies for fibroblast growth factor-22014

    • Author(s)
      Tanaka, M, Yamaguchi, M, Shiota, M, Kawamoto, Y, Takahashi, K, Inagaki, A, Osada-Oka, M, Harada, A., Wanibuchi, H, Izumi, Y, Miura, K, Iwao, H, Ohkawa, Y
    • Journal Title

      Monoclon Antib Immunodiagn Immunother

      Volume: 33 Pages: 261-269

    • DOI

      10.1089/mab.2013.0085

    • Peer Reviewed
  • [Journal Article] Comparative proteomics analysis of gastric cancer stem cells2014

    • Author(s)
      Morisaki, T, Yashiro, M, Kakehashi, A, Inagaki, A, Kinoshita, H, Fukuoka, T, Kasashima, H, Masuda, G, Sakurai, K, Kubo, N, Muguruma, K, Ohira, M., Wanibuchi, H, Hirakawa, K
    • Journal Title

      PLoS One

      Volume: 9 Pages: e110736

    • DOI

      10.1371/journal.pone.0110736

    • Peer Reviewed
  • [Journal Article] Nanosized zinc oxide particles do not promote DHPN-induced lung carcinogenesis but cause reversible epithelial hyperplasia of terminal bronchioles2014

    • Author(s)
      Xu, J., Futakuchi, M., Alexander, D.B., Fukamachi, K., Numano, T., Suzui, M., Shimizu, H., Omori, T., Kanno, J., Hirose, A., and Tsuda, H
    • Journal Title

      Archives of toxicology

      Volume: 88 Pages: 65-75

    • DOI

      10.1007/s00204-013-1086-5

    • Peer Reviewed
  • [Journal Article] Size-and shape-dependent pleural translocation, deposition, fibrogenesis, and mesothelial proliferation by multiwalled carbon nanotubes2014

    • Author(s)
      Xu, J., Alexander, D.B., Futakuchi, M., Numano, T., Fukamachi, K., Suzui, M., Omori, T., Kanno, J., Hirose, A., and Tsuda, H
    • Journal Title

      Cancer Sci

      Volume: 105 Pages: 763-769

    • DOI

      10.1111/cas.12437

    • Peer Reviewed
  • [Journal Article] Comparative study of toxic effects of anatase and rutile type nanosized titanium dioxide particles in vivo and in vitro2014

    • Author(s)
      Numano, T., Xu, J., Futakuchi, M., Fukamachi, K., Alexander, D.B., Furukawa, F., Kanno, J., Hirose, A., Tsuda, H., and Suzui, M
    • Journal Title

      Asian Pacific J Cancer Prev

      Volume: 15 Pages: 929-935

    • Peer Reviewed
  • [Journal Article] Rat N-ERC/mesothelin as a marker for in vivo screening of drugs against pancreas cancer2014

    • Author(s)
      Fukamachi, K., Iigo, M., Hagiwara, Y., Shibata, K., Futakuchi, M., Alexander, D.B., Hino, O., Suzui, M., and Tsuda, H
    • Journal Title

      Plos One

      Volume: 9 Pages: e111481

    • DOI

      10.1371/journal.pone.0111481

    • Peer Reviewed
  • [Journal Article] Murine Herc6 plays a critical role in protein ISGylation in vivo and has an ISGylation independent function in seminal vesicles2014

    • Author(s)
      Arimoto, K.-i., Hishiki, T., Kiyonari, H., Abe, T., Cheng, C., Yan, M., Fan, J.-B., Futakuchi, M., Tsuda, H., Murakami, Y., Suzuki, H., Zhang, D.-E., and Shimotohno, K.
    • Journal Title

      J. Interferon & Cytokine Res

    • DOI

      10.1089/jir.2014.0113

    • Peer Reviewed
  • [Journal Article] Significance of the progesterone receptor and epidermal growth factor receptor, but not the estrogen receptor, in chemically induced lung carcinogenesis in female A/J mice2014

    • Author(s)
      Kishi S, Yokohira M, Yamakawa K, Saoo K, Imaida K
    • Journal Title

      Oncol. Lett

      Volume: 8 Pages: 2379-2386

    • Peer Reviewed
  • [Journal Article] Napsin A is possibly useful marker to predict the tumorigenic potential of lung bronchiolo-alveolar hyperplasia in F344 rats2014

    • Author(s)
      Yokohira M, Kishi S, Yamakawa K, Nakano Y, Ninomiya F, Kinouch s, Tanizawa J, Saoo K, Imaida K
    • Journal Title

      Exp. Toxicol. Pathol

      Volume: 66 Pages: 117-123

    • DOI

      10.1016/j.etp.2013.11.002

    • Peer Reviewed
  • [Journal Article] The peroxisome proliferator-activated receptor(PPAR)a agonist fenofibrate suppresses chemically induced lung alveolar proliferative lesions in male obese hyperlipidemic mice2014

    • Author(s)
      Kuno T, Hata K, Takamatsu M, Hara A, Hirose Y, Takahashi S, Imaida K, Tanaka T
    • Journal Title

      Int. J. Mol. Sci

      Volume: 15 Pages: 9160-9172

    • DOI

      10.3390/ijms15059160

    • Peer Reviewed
  • [Journal Article] Immunohistochemical characteristics of surfactant proteins-A, -B, -C and -D in inflammatory and tumorigenic lung lesions of F344 rats2014

    • Author(s)
      Yokohira M, Yamakawa K, Nakano Y, Numano T, Furukawa F, Kishi S, Ninomiya F, Kanie S, Hitotsumachi H, Saoo K, Imaida K
    • Journal Title

      J. Toxicol. Pathol

      Volume: 27 Pages: 175-182

    • DOI

      10.1293/tox.2014-0020

    • Peer Reviewed
  • [Journal Article] Rat strain differences in levels and effects of chronic inflammation due to intratracheal instillation of quartz on lung tumorigenesis induced by DHPN2014

    • Author(s)
      Nakano Y, Yokohira M, Hashimoto N, Yamakawa K, Kishi S, Ninomiya F, Kanie S, Saoo K, Imaida K
    • Journal Title

      Exp. Toxicol. Pathol

      Volume: 66 Pages: 391-401

    • DOI

      10.1016/j.etp.2014.06.002

    • Peer Reviewed
  • [Journal Article] Hepatoid giant cell tumor of tendon sheath-A rare morphologic variant case report2014

    • Author(s)
      Yoshimoto, T., Motoi, N., Kanda, H., Tanizawa, T., Shimoji, T., Matsumoto, S., Mukai, H., Ishikawa, Y., Machinami, R.
    • Journal Title

      Pathology Res. Practice

      Volume: 14 Pages: 167-168

    • DOI

      10.1016/j.prp.2014.05.012

    • Peer Reviewed
  • [Journal Article] FFT法と領域法を組み合わせたDNA ploidy解析によるがん診断法の研究2014

    • Author(s)
      日向奈恵、神田浩明、塩山高広、鈴木あかね、武田朴、石川雄一、山口俊晴、加藤洋
    • Journal Title

      生体医工学

      Volume: 52 Pages: 136-144

    • DOI

      10.11239/jsmbe.52.136

    • Peer Reviewed
  • [Journal Article] Premature termination of reprogramming in vivo leads to cancer development through altered epigenetic regulation2014

    • Author(s)
      Ohnishi K., Semi K., Yamamoto T., Shimizu M., Tanaka A., Mitsunaga K., Okita K., Osafune K., Arioka Y., Maeda T., Soejima H., Moriwaki H., Yamanaka S., Woltjen K., Yamada Y.
    • Journal Title

      Cell

      Volume: 156 Pages: 663-77

    • DOI

      10.1016/j.cell.2014.01.005

    • Peer Reviewed
  • [Journal Article] A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer2014

    • Author(s)
      Al Olama, A.A., Kote-Jarai Z., Bemdt S.I., Conti D.V., Schumacher F., Han Y., Benlloch S., Hazelett D.J., Wang Z., Saunders E., Leongamornlert D., Lindstrom S., Jugurnauth-Little S., Dadaev T., Tymrakiewicz M., Stram D.O., Rand K., Wan P., Stram A., Kubo M., et al.
    • Journal Title

      Nat Genet

      Volume: 46 Pages: 1103-1109

    • DOI

      10.1038/ng.3094

    • Peer Reviewed
  • [Journal Article] Infection with Porphyromonas gingivalis exacerbates endothelial injury in obese mice2014

    • Author(s)
      Ao, M., Miyauchi M., Inubushi T., Kitagawa M., Furusho H., Ando T., Ayuningtyas N.F., Nagasaki A., Ishihara K., Tahara H., Kozai K. and Takata T.
    • Journal Title

      PLoS One

      Volume: 9 Pages: e110519

    • DOI

      10.1371/journal.pone.0110519

    • Peer Reviewed
  • [Journal Article] Development of a SNP set for human identification : A set with high powers of discrimination which yields high genetic information from naturally degraded DNA samples in the Thai population2014

    • Author(s)
      Boonyarit, H., Mahasirimongkol S., Chavalvechakul N., Aoki M., Amitani H., Hosono N., Kamatani N., Kubo M. and Lertrit P.
    • Journal Title

      Forensic Sci Int Genet

      Volume: 11 Pages: 166-173

    • DOI

      10.1016/j.fsigen.2014.03.010

    • Peer Reviewed
  • [Journal Article] Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1,5q14.3 and 15q26.12014

    • Author(s)
      Cai, Q., Zhang B., Sung H., Low S.K., Kweon S.S., Shen C.Y., Matsuo K., Teo S.H., Kim M.K., Iwasaki M., Hartman M., Takahashi A., Ashikawa K., Matsuda K., Ito H., Kasuga Y., Iwata H., Tsugane S., Nakamura Y., Kubo M., et al.
    • Journal Title

      Nat Genet

      Volume: 46 Pages: 886-890

    • DOI

      10.1038/ng.3041

    • Peer Reviewed
  • [Journal Article] Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians2014

    • Author(s)
      Chen, P., Takeuchi F., Lee J.Y., Li H., Wu J.Y., Tabara Y., Goodarzi M.O., Pereira M.A., Kim Y.J., Go M.J., Stram D.O., Vithana E., Isono M., Yamamoto K., Ohnaka K., Takayanagi R., Kita Y., Ueshima H., Okada Y., Kubo M., et al.
    • Journal Title

      Diabetes

      Volume: 63 Pages: 2551-2562

    • DOI

      10.2337/db13-1815

    • Peer Reviewed
  • [Journal Article] Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101(Alliance)2014

    • Author(s)
      Chhibber, A., Mefford J., Stahl E.A., Pendergrass S.A., Baldwin R.M., Owzar K., Li M., Winer E.P., Hudis C.A., Zembutsu H., Kubo M., Nakamura Y., McLeod H.L., Ratain M.J., Shulman L.N., Ritchie M.D., Plenge R.M., Witte J.S. and Kroetz D.L.
    • Journal Title

      Pharmacogenomics J

      Volume: 14 Pages: 336-342

    • DOI

      10.1038/tpj.2014.2

    • Peer Reviewed
  • [Journal Article] Establishment of CYP2D6 reference samples by multiple validated genotyping platforms2014

    • Author(s)
      Fang, H., Liu X., Ramirez J., Choudhury N., Kubo M., Im H.K., Konkashbaev A., Cox N.J., Ratain M.J., Nakamura Y. and O'Donnell P.H.
    • Journal Title

      Pharmacogenomics J

      Volume: 14 Pages: 564-572

    • DOI

      10.1038/tpj.2014.27

    • Peer Reviewed
  • [Journal Article] Genetic variants in transcription factors are associated with the pharmacokinetics and pharmacodynamics of metformin2014

    • Author(s)
      Goswami, S., Yee S.W., Stocker S., Mosley J.D., Kubo M., Castro R., Mefford J.A., Wen C., Liang X., Witte J., Brett C., Maeda S., Simpson M.D., Hedderson M.M., Davis R.L., Roden D.M., Giacomini K.M. and Savic R.M.
    • Journal Title

      Clin Pharmacol Ther

      Volume: 96 Pages: 370-379

    • DOI

      10.1038/clpt.2014.109

    • Peer Reviewed
  • [Journal Article] A novel RET rearrangement (ACBD5/RET) by pericentric inversion, inv(10)(p12.1 ; q11.2), in papillary thyroid cancer from an atomic bomb survivor exposed to high-dose radiation2014

    • Author(s)
      Hamatani, K., Eguchi H., Koyama K., Mukai M., Nakachi K. and Kusunoki Y.
    • Journal Title

      Oncol Rep

      Volume: 32 Pages: 1809-1814

    • DOI

      10.3892/or.2014.3449

    • Peer Reviewed
  • [Journal Article] Associations between hOGG1 Ser326Cys polymorphism and increased body mass index and fasting glucose level in the Japanese general population2014

    • Author(s)
      Hara, M., Nakamura K., Nanri H., Nishida Y., Hishida A., Kawai S., Hamajima N., Kita Y., Suzuki S., Mantjoro E.M., Ohnaka K., Uemura H., Matsui D., Oze I., Mikami H., Kubo M., Tanaka H. and Japan Multi-Institutional Collaborative Cohort Study Group
    • Journal Title

      J Epidemiol

      Volume: 24 Pages: 379-384

    • Peer Reviewed
  • [Journal Article] Cancer Philosophy~Thinking“Cancer Cells”Deeply2014

    • Author(s)
      Hino, O
    • Journal Title

      Juntendo Medical Journal

      Volume: 60 Pages: 200-209

    • Peer Reviewed
  • [Journal Article] Telomeric g-tail length and hospitalization for cardiovascular events in hemodialysis patients2014

    • Author(s)
      Hirashio, S., Nakashima A., Doi S., Anno K., Aoki E., Shimamoto A., Yorioka N., Kohno N., Masaki T. and Tahara H
    • Journal Title

      Clin J Am Soc Nephrol

      Volume: 9 Pages: 2117-2122

    • DOI

      10.2215/CJN.10010913

    • Peer Reviewed
  • [Journal Article] Retrospective analysis of large-scale research screening of construction workers for the early diagnosis of mesothelioma2014

    • Author(s)
      Hirohashi, T., Igarashi K., Abe M., Maeda M. and Hino O.
    • Journal Title

      Mol Clin Oncol

      Volume: 2 Pages: 26-30

    • DOI

      10.3892/mco.2013.197

    • Peer Reviewed
  • [Journal Article] CBP-93872 inhibits NBS1-mediated ATR activation, abrogating maintenance of the DNA double-strand break-specific G2 checkpoint2014

    • Author(s)
      Hirokawa, T., Shiotani B., Shimada M., Murata K., Johmura Y., Haruta M., Tahara H., Takeyama H. and Nakanishi M.
    • Journal Title

      Cancer Res

      Volume: 74 Pages: 3880-3889

    • DOI

      10.1158/0008-5472.CAN-13-3604

    • Peer Reviewed
  • [Journal Article] GCK, GCKR polymorphisms and risk of chronic kidney disease in Japanese individuals : data from the J-MICC Study2014

    • Author(s)
      Hishida, A., Takashima N., Turin T.C., Kawai S., Wakai K., Hamajima N., Hosono S., Nishida Y., Suzuki S., Nakahata N., Mikami H., Ohnaka K., Matsui D., Katsuura-Kamano S., Kubo M., Tanaka H. and Kita Y.
    • Journal Title

      J Nephrol

      Volume: 27 Pages: 143-149

    • DOI

      10.1007/s40620-013-0025-0

    • Peer Reviewed
  • [Journal Article] Polymorphisms of genes involved in lipid metabolism and risk of chronic kidney disease in Japanese-cross-sectional data from the J-MICC study2014

    • Author(s)
      Hishida, A., Wakai K., Naito M., Suma S., Sasakabe T., Hamajima N., Hosono S., Horita M., Turin T.C., Suzuki S., Kairupan T.S., Mikami H., Ohnaka K., Watanabe I., Uemura H., Kubo M., Tanaka H, and J-Micc Study Group
    • Journal Title

      Lipids Health Dis

      Volume: 13 Pages: 162

    • DOI

      10.1186/1476-511X-13-162

    • Peer Reviewed
  • [Journal Article] TERT attenuated ER stress-induced cell death2014

    • Author(s)
      Hosoi, T., Inoue Y., Nakatsu K., Matsushima N., Kiyose N., Shimamoto A., Tahara H. and Ozawa K.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 447 Pages: 378-382

    • DOI

      10.1016/j.bbrc.2014.04.034

    • Peer Reviewed
  • [Journal Article] Circulating tumor cell count during zoledronic acid treatment in men with metastatic prostate cancer : a pilot study2014

    • Author(s)
      Ide, H., Lu Y., Tanaka T., Wakumoto Y., Kitamura K., Muto S., Yamaguchi R., Masumori N. and Horie S.
    • Journal Title

      Prostate Int

      Volume: 2 Pages: 147-151

    • DOI

      10.12954/PI.14056

    • Peer Reviewed
  • [Journal Article] Asbestos-related mesothelioma : Prevention, early detection, treatment2014

    • Author(s)
      Imai, M. and Hino O.
    • Journal Title

      JSM Clinical Oncology and Research

      Volume: 2 Issue: 3 Pages: 1018

    • Peer Reviewed
  • [Journal Article] ERC/mesothelin is expressed in human gastric cancer tissues and cell lines2014

    • Author(s)
      Ito, T., Kajino K., Abe M., Sato K., Maekawa H., Sakurada M., Orita H., Wada R., Kajiyama Y. and Hino O.
    • Journal Title

      Oncol Rep

      Volume: 31 Pages: 27-33

    • DOI

      10.3892/or.2013.2803

    • Peer Reviewed
  • [Journal Article] Association of EPAS1 gene rs4953354 polymorphism with susceptibility to lung adenocarcinoma in female Japanese non-smokers2014

    • Author(s)
      Iwamoto, S., Tanimoto K., Nishio Y., Putra A.C., Fuchita H., Ohe M., Sutani A., Kuraki T., Hiyama K., Murakami I., Eguchi H. and Isobe T.
    • Journal Title

      J Thorac Oncol

      Volume: 9 Pages: 1709-1713

    • DOI

      10.1097/JTO.0000000000000309

    • Peer Reviewed
  • [Journal Article] Citalopram and escitalopram plasma drug and metabolite concentrations : genome-wide associations2014

    • Author(s)
      Ji, Y., Schaid D.J., Desta Z., Kubo M., Batzler A.J., Snyder K., Mushiroda T., Kamatani N., Ogburn E., Hall-Flavin D., Flockhart D., Nakamura Y., Mrazek D.A. and Weinshilboum R.M.
    • Journal Title

      Br J Clin Pharmacol

      Volume: 78 Pages: 373-383

    • DOI

      10.1111/bcp.12348

    • Peer Reviewed
  • [Journal Article] EP2 signaling mediates suppressive effects of celecoxib on androgen receptor expression and cell proliferation in prostate cancer2014

    • Author(s)
      Kashiwagi, E., Shiota M., Yokomizo A., Inokuchi J., Uchiumi T. and Naito S.
    • Journal Title

      Prostate Cancer Prostatic Dis

      Volume: 17 Pages: 10-17

    • DOI

      10.1038/pcan.2013.53

    • Peer Reviewed
  • [Journal Article] A polymorphism near MC4R gene (rs17782313) is associated with serum triglyceride levels in the general Japanese population : the J-MICC Study2014

    • Author(s)
      Katsuura-Kamano, S., Uemura H., Arisawa K., Yamaguchi M., Hamajima N., Wakai K., Okada R., Suzuki S., Taguchi N., Kita Y., Ohnaka K., Kairupan T.S., Matsui D., Oze I., Mikami H., Kubo M. and Tanaka H.
    • Journal Title

      Endocrine

      Volume: 47 Pages: 81-89

    • DOI

      10.1007/s12020-014-0306-y

    • Peer Reviewed
  • [Journal Article] Trans-ethnic meta-analysis of white blood cell phenotypes2014

    • Author(s)
      Keller, M.F., Reiner A.P., Okada Y., van Rooij F.J., Johnson A.D., Chen M.H., Smith A.V., Morris A.P., Tanaka T., Ferrucci L., Zonderman A.B., Lettre G., Kamatani Y., Matsuda K., Kamatani N., Nakamura Y., Kubo M., Takahashi A., Wilson J.G., BioBank Japan Project Working Groups, et al.
    • Journal Title

      Hum Mol Genet

      Volume: 23 Pages: 6944-6960

    • DOI

      10.1093/hmg/ddu401

    • Peer Reviewed
  • [Journal Article] SOD3 acts as a tumor suppressor in PC-3 prostate cancer cells via hydrogen peroxide accumulation2014

    • Author(s)
      Kim, J., Mizokami A., Shin M., Izumi K., Konaka H., Kadono Y., Kitagawa Y., Keller E.T., Zhang J. and Namiki M.
    • Journal Title

      Anticancer Res

      Volume: 34 Pages: 2821-2831

    • Peer Reviewed
  • [Journal Article] A genome-wide association study to identify genomic modulators of rate control therapy in patients with atrial fibrillation2014

    • Author(s)
      Kolek, M.J., Edwards T.L., Muhammad R., Balouch A., Shoemaker M.B., Blair M.A., Kor K.C., Takahashi A., Kubo M., Roden D.M., Tanaka T. and Darbar D.
    • Journal Title

      Am J Cardiol

      Volume: 114 Pages: 593-600

    • DOI

      10.1016/j.amjcard.2014.05.040

    • Peer Reviewed
  • [Journal Article] Combination of bevacizumab and acyclic retinoid inhibits the growth of hepatocellular carcinoma xenografts2014

    • Author(s)
      Kubota, M., Shimizu M., Baba A., Ohno T., Kochi T., Shirakami Y. and Moriwaki H.
    • Journal Title

      J Nutr Sci Vitaminol (Tokyo)

      Volume: 60 Pages: 357-362

    • DOI

      10.3177/jnsv.60.357

    • Peer Reviewed
  • [Journal Article] Aromatase inhibitor-associated bone fractures : a case-cohort GWAS and functional genomics2014

    • Author(s)
      Liu, M., Goss P.E., Ingle J.N., Kubo M., Furukawa Y., Batzler A., Jenkins G.D., Carlson E.E., Nakamura Y., Schaid D.J., Chapman J.A., Shepherd L.E., Ellis M.J., Khosla S., Wang L. and Weinshilboum R.M.
    • Journal Title

      Mol Endocrinol

      Volume: 28 Pages: 1740-1751

    • DOI

      10.1210/me.2014-1147

    • Peer Reviewed
  • [Journal Article] Minimal experimental requirements for definition of extracellular vesicles and their functions : a position statement from the International Society for Extracellular Vesicles2014

    • Author(s)
      Lotvall, J., Hill A.F., Hochberg F., Buzas E.I., Di Vizio D., Gardiner C., Gho Y.S., Kurochkin I.V., Mathivanan S., Quesenberry P., Sahoo S., Tahara H., Wauben M.H., Witwer K.W. and Thery C.
    • Journal Title

      J Extracell Vesicles

      Volume: 3 Pages: 26913

    • DOI

      10.3402/jev.v3.26913

    • Peer Reviewed
  • [Journal Article] Genome-wide association study : a useful tool to identify common genetic variants associated with drugtoxicity and efficacy in cancer pharmacogenomics2014

    • Author(s)
      Low, S.K., Takahashi A., Mushiroda T. and Kubo M.
    • Journal Title

      Clin Cancer Res

      Volume: 20 Pages: 2541-2552

    • DOI

      10.1158/1078-0432.CCR-13-2755

    • Peer Reviewed
  • [Journal Article] Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese2014

    • Author(s)
      Lubitz, S.A., Lunetta K.L., Lin H., Arking D.E., Trompet S., Li G., Krijthe B.P., Chasman D.I., Barnard J., Kleber M.E., Dorr M., Ozaki K., Smith A.V., Muller-Nurasyid M., Walter S., Agarwal S.K., Kubo M., Tanaka T., Heckbert S.R., Jukema J.W., et al.
    • Journal Title

      J Am Coll Cardiol

      Volume: 63 Pages: 1200-1210

    • DOI

      10.1016/j.jacc.2013.12.015

    • Peer Reviewed
  • [Journal Article] Ethical challenges for the design and conduct of mega-biobanking from Great East Japan Earthquake victims2014

    • Author(s)
      Matsui, K. and Tashiro S.
    • Journal Title

      BMC Med Ethics

      Volume: 15 Pages: 55

    • DOI

      10.1186/1472-6939-15-55

    • Peer Reviewed
  • [Journal Article] DSE-FRET : A new anticancer drug screening assay for DNA binding proteins2014

    • Author(s)
      Miyagi, T., Shiotani B., Miyoshi R., Yamamoto T., Oka T., Umezawa K., Ochiya T., Takano M. and Tahara H.
    • Journal Title

      Cancer Sci

      Volume: 105 Pages: 870-874

    • DOI

      10.1111/cas.12420

    • Peer Reviewed
  • [Journal Article] Proposed salvage treatment strategy for biochemical failure after radical prostatectomy in patients with prostate cancer : a retrospective study2014

    • Author(s)
      Miyake, M., Tanaka N., Asakawa I., Morizawa Y., Anai S., Torimoto K., Aoki K., Yoneda T., Hasegawa M., Konishi N. and Fujimoto K.
    • Journal Title

      Radiat Oncol

      Volume: 9 Pages: 208

    • DOI

      10.1186/1748-717X-9-208

    • Peer Reviewed
  • [Journal Article] Photodynamic diagnosis of shed prostate cancer cells in voided urine treated with 5-aminolevulinic acid2014

    • Author(s)
      Nakai, Y., Anai S., Kuwada M., Miyake M., Chihara Y., Tanaka N., Hirayama A., Yoshida K., Hirao Y. and Fujimoto K.
    • Journal Title

      BMC Urol

      Volume: 14 Pages: 59

    • DOI

      10.1186/1471-2490-14-59

    • Peer Reviewed
  • [Journal Article] A genome-wide association study identifies susceptibility loci for ossification of the posterior longitudinal ligament of the spine2014

    • Author(s)
      Nakajima, M., Takahashi A., Tsuji T., Karasugi T., Baba H., Uchida K., Kawabata S., Okawa A., Shindo S., Takeuchi K., Taniguchi Y., Maeda S., Kashii M., Seichi A., Nakajima H., Kawaguchi Y., Fujibayashi S., Takahata M., Tanaka T., Kubo M., et al.
    • Journal Title

      Nat Genet

      Volume: 46 Pages: 1012-1016

    • DOI

      10.1038/ng.3045

    • Peer Reviewed
  • [Journal Article] Common dysfunctional variants of ABCG2 have stronger impact on hyperuricemia progression than typical environmental risk factors2014

    • Author(s)
      Nakayama, A., Matsuo H., Nakaoka H., Nakamura T., Nakashima H., Takada Y., Oikawa Y., Takada T., Sakiyama M., Shimizu S., Kawamura Y., Chiba T., Abe J., Wakai K., Kawai S., Okada R., Tamura T., Shichijo Y., Akashi A., Suzuki H., et al.
    • Journal Title

      Sci Rep

      Volume: 4 Pages: 5227

    • DOI

      10.1038/srep05227

    • Peer Reviewed
  • [Journal Article] Objectively measured physical activity and inflammatory cytokine levels in middle-aged Japanese people2014

    • Author(s)
      Nishida, Y., Higaki Y., Taguchi N., Hara M., Nakamura K., Nanri H., Imaizumi T., Sakamoto T., Horita M., Shinchi K. and Tanaka K.
    • Journal Title

      Prev Med

      Volume: 64 Pages: 81-87

    • DOI

      10.1016/j.ypmed.2014.04.004

    • Peer Reviewed
  • [Journal Article] Association between KCNJ6 (GIRK2) gene polymorphism rs2835859 and post-operative analgesia, pain sensitivity, and nicotine dependence2014

    • Author(s)
      Nishizawa, D., Fukuda K., Kasai S., Ogai Y., Hasegawa J., Sato N., Yamada H., Tanioka F., Sugimura H., Hayashida M. and Ikeda K.
    • Journal Title

      J Pharmacol Sci

      Volume: 126 Pages: 253-263

    • Peer Reviewed
  • [Journal Article] Pyrrole-imidazole polyamide targeted to break fusion sites in TMPRSS2 and ERG gene fusion represses prostate tumor growth2014

    • Author(s)
      Obinata, D., Ito A., Fujiwara K., Takayama K., Ashikari D., Murata Y., Yamaguchi K., Urano T., Fujimura T., Fukuda N., Soma M., Watanabe T., Nagase H., Inoue S. and Takahashi S.
    • Journal Title

      Cancer Sci

      Volume: 105 Pages: 1272-1278

    • DOI

      10.1111/cas.12493

    • Peer Reviewed
  • [Journal Article] IFNL4/IL-28B haplotype structure and its impact on susceptibility to hepatitis C virus and treatment response in the Japanese population2014

    • Author(s)
      Ochi, H., Miki D., Hayes C.N., Abe H., Hayashida Y., Kubo M. and Chayama K.
    • Journal Title

      J Gen Virol

      Volume: 95 Pages: 1297-1306

    • DOI

      10.1099/vir.0.060103-0

    • Peer Reviewed
  • [Journal Article] Genetics of rheumatoid arthritis contributes to biology and drug discovery2014

    • Author(s)
      Okada, Y., Wu D., Trynka G., Raj T., Terao C., Ikari K., Kochi Y., Ohmura K., Suzuki A., Yoshida S., Graham R.R., Bhangale T., Denny J.C., Carroll R.J., Eyler A.E., Kawaguchi T., Kamatani Y., Taniguchi A., Yamada R., Kubo M., et al.
    • Journal Title

      Nature

      Volume: 506 Pages: 376-381

    • DOI

      10.1038/nature12873

    • Peer Reviewed
  • [Journal Article] Survey of survival among patients with hepatitis C virus-related hepatocellular carcinoma treated with peretinoin, an acyclic retinoid, after the completion of a randomized, placebo-controlled trial2014

    • Author(s)
      Okita, K., Izumi N., Ikeda K., Osaki Y., Numata K., Ikeda M., Kokudo N., Imanaka K., Nishiguchi S., Kondo S., Nishigaki Y., Shiomi S., Ueshima K., Isoda N., Karino Y., Kudo M., Tanaka K., Kaneko S., Moriwaki H., Makuuchi M., et al.
    • Journal Title

      J Gastroenterol

    • DOI

      10.1007/s00535-014-0996-1

    • Description
      Epub ahead of print
    • Peer Reviewed
  • [Journal Article] Coffee and green tea consumption is associated with upper aerodigestive tractcancer in Japan2014

    • Author(s)
      Oze, I., Matsuo K., Kawakita D., Hosono S., Ito H., Watanabe M., Hatooka S., Hasegawa Y., Shinoda M., Tajima K. and Tanaka H.
    • Journal Title

      Int J Cancer

      Volume: 135 Issue: 2 Pages: 391-400

    • DOI

      10.1002/ijc.28653

    • Peer Reviewed
  • [Journal Article] Higher levels of antibodies to the tumour-associated antigen cyclin B1 in cancer-free individuals than in patients with breast cancer2014

    • Author(s)
      Pandey, J.P., Kistner-Griffin E., Namboodiri A.M., Iwasaki M., Kasuga Y., Hamada G.S. and Tsugane S.
    • Journal Title

      Clin Exp Immunol

      Volume: 178 Pages: 75-78

    • DOI

      10.1111/cei.12385

    • Peer Reviewed
  • [Journal Article] Genetic predictors associated with improvement of asthma symptoms in response to inhaled corticosteroids2014

    • Author(s)
      Park, H.W., Dahlin A., Tse S., Duan Q.L., Schuemann B., Martinez F.D., Peters S.P., Szefler S.J., Lima J.J., Kubo M., Tamari M. and Tantisira K.G.
    • Journal Title

      J Allergy Clin Immunol

      Volume: 133 Pages: 664-669

    • DOI

      10.1016/j.jaci.2013.12.1042

    • Peer Reviewed
  • [Journal Article] Acute case-fatality rates of stroke and acute myocardial infarction in a Japanese population : Takashima stroke and AMI registry, 1989-20052014

    • Author(s)
      Rumana, N., Kita Y., Turin T.C., Nakamura Y., Takashima N., Ichikawa M., Sugihara H., Morita Y., Hirose K., Kawakami K., Okayama A., Miura K. and Ueshima H.
    • Journal Title

      Int J Stroke

      Volume: 9 Suppl A100 Pages: 69-75

    • DOI

      10.1111/ijs.12288

    • Peer Reviewed
  • [Journal Article] A common variant of organic anion transporter 4(OAT4/SLC22A11) gene is associated with renal underexcretion type gout2014

    • Author(s)
      Sakiyama, M., Matsuo H., Shimizu S., Nakashima H., Nakayama A., Chiba T., Naito M., Takada T., Suzuki H., Hamajima N., Ichida K., Shimizu T. and Shinomiya N.
    • Journal Title

      Drug Metab Pharmacokinet

      Volume: 29 Pages: 208-210

    • Peer Reviewed
  • [Journal Article] Ethnic Differences in ATP-binding Cassette Transporter, Sub-family G, Member2 (ABCG2/BCRP) : Genotype Combinations and Estimated Functions2014

    • Author(s)
      Sakiyama, M., Matsuo H., Takada Y., Nakamura T., Nakayama A., Takada T., Kitajiri S., Wakai K., Suzuki H. and Shinomiya N.
    • Journal Title

      Drug Metab Pharmacokinet

      Volume: 29 Pages: 490-492

    • DOI

      10.2133/dmpk.DMPK-14-SC-041

    • Peer Reviewed
  • [Journal Article] Newly established ELISA for N-ERC/mesothelin improves diagnostic accuracy in patients with suspected pleural mesothelioma2014

    • Author(s)
      Sato, T., Suzuki Y., Mori T., Maeda M., Abe M., Hino O. and Takahashi K.
    • Journal Title

      Cancer Med

      Volume: 3 Pages: 1377-1384

    • DOI

      10.1002/cam4.297

    • Peer Reviewed
  • [Journal Article] The construction of risk prediction models using GWAS data and its application to a type 2 diabetes prospective cohort2014

    • Author(s)
      Shigemizu, D., Abe T., Morizono T., Johnson T.A., Boroevich K.A., Hirakawa Y., Ninomiya T., Kiyohara Y., Kubo M., Nakamura Y., Maeda S. and Tsunoda T.
    • Journal Title

      PLoS One

      Volume: 9 Pages: e92549

    • DOI

      10.1371/journal.pone.0092549

    • Peer Reviewed
  • [Journal Article] Reprogramming suppresses premature senescence phenotypes of Werner syndromecells and maintains chromosomal stability over long-term culture2014

    • Author(s)
      Shimamoto, A., Kagawa H., Zensho K., Sera Y., Kazuki Y., Osaki M., Oshimura M., Ishigaki Y., Hamasaki K., Kodama Y., Yuasa S., Fukuda K., Hirashima K., Seimiya H., Koyama H., Shimizu T., Takemoto M., Yokote K., Goto M. and Tahara H.
    • Journal Title

      PLoS One

      Volume: 9 Pages: e112900

    • DOI

      10.1371/journal.pone.0112900

    • Peer Reviewed
  • [Journal Article] Gender-specific associations of perceived stress and coping strategies with C-reactive protein in middle-aged and older men and women2014

    • Author(s)
      Shimanoe, C., Otsuka Y., Hara M., Nanri H., Nishida Y., Nakamura K., Higaki Y., Imaizumi T., Taguchi N., Sakamoto T., Horita M., Shinchi K. and Tanaka K.
    • Journal Title

      Int J Behav Med

      Volume: 21 Pages: 821-832

    • DOI

      10.1007/s12529-013-9341-y

    • Peer Reviewed
  • [Journal Article] Pharmaceutical and nutraceutical approaches for preventing liver carcinogenesis : chemoprevention of hepatocellular carcinoma using acyclic retinoid and branched-chain amino acids2014

    • Author(s)
      Shimizu, M., Shirakami Y., Hanai T., Imai K., Suetsugu A., Takai K., Shiraki M. and Moriwaki H.
    • Journal Title

      Mol Nutr Food Res

      Volume: 58 Pages: 124-135

    • DOI

      10.1002/mnfr.201300538

    • Peer Reviewed
  • [Journal Article] Impaired 8-hydroxyguanine repair activity of MUTYH variant p. Arg109Trp found in a Japanese patient with early-onset colorectal cancer2014

    • Author(s)
      Shinmura, K., Goto M., Tao H., Kato H., Suzuki R., Nakamura S., Matsuda T., Yin G., Morita M., Kono S. and Sugimura H.
    • Journal Title

      Oxid Med Cell Longev

      Volume: 2014 Pages: 617351

    • DOI

      10.1155/2014/617351

    • Peer Reviewed
  • [Journal Article] RSPO fusion transcripts in colorectal cancer in Japanese population2014

    • Author(s)
      Shinmura, K., Kahyo T., Kato H., Igarashi H., Matsuura S., Nakamura S., Kurachi K., Nakamura T., Ogawa H., Funai K., Tanahashi M., Niwa H. and Sugimura H.
    • Journal Title

      Mol Biol Rep

      Volume: 41 Pages: 5375-5384

    • DOI

      10.1007/s11033-014-3409-x

    • Peer Reviewed
  • [Journal Article] PLK4 overexpression and its effect on centrosome regulation and chromosome stability in human gastric cancer2014

    • Author(s)
      Shinmura, K., Kurabe N., Goto M., Yamada H., Natsume H., Konno H. and Sugimura H.
    • Journal Title

      Mol Biol Rep

      Volume: 41 Pages: 6635-6644

    • DOI

      10.1007/s11033-014-3546-2

    • Peer Reviewed
  • [Journal Article] Transgenic expression of the N525S-tuberin variant in Tsc2 mutant (Eker) rats causes dominant embryonic lethality2014

    • Author(s)
      Shiono, M., Kobayashi T., Takahashi R., Ueda M., Ishioka C. and Hino O
    • Journal Title

      Sci Rep

      Volume: 4 Pages: 5927

    • DOI

      10.1038/srep05927

    • Peer Reviewed
  • [Journal Article] The oncological outcomes and risk stratification in docetaxel chemotherapy for castration-resistant prostate cancer2014

    • Author(s)
      Shiota, M., Yokomizo A., Adachi T., Koga H., Yamaguchi A., Imada K., Takeuchi A., Kiyoshima K., Inokuchi J., Tatsugami K. and Naito S.
    • Journal Title

      Jpn J Clin Oncol

      Volume: 44 Pages: 860-867

    • DOI

      10.1093/jjco/hyu081

    • Peer Reviewed
  • [Journal Article] The feature of metabolic syndrome is a risk factor for biochemical recurrence after radical prostatectomy2014

    • Author(s)
      Shiota, M., Yokomizo A., Takeuchi A., Imada K., Kiyoshima K., Inokuchi J., Tatsugami K. and Naito S.
    • Journal Title

      J Surg Oncol

      Volume: 110 Pages: 476-481

    • DOI

      10.1002/jso.23677

    • Peer Reviewed
  • [Journal Article] Risk factors for febrile neutropenia in patients receiving docetaxel chemotherapy for castration-resistant prostate cancer2014

    • Author(s)
      Shiota, M., Yokomizo A., Takeuchi A., Imada K., Kiyoshima K., Inokuchi J., Tatsugami K. and Naito S.
    • Journal Title

      Support Care Cancer

      Volume: 22 Pages: 3219-3226

    • DOI

      10.1007/s00520-014-2328-7

    • Peer Reviewed
  • [Journal Article] Integrated analysis of whole genome and transcriptome sequencing reveals diverse transcriptomic aberrations driven by somatic genomic changes in liver cancers2014

    • Author(s)
      Shiraishi, Y., Fujimoto A., Furuta M., Tanaka H., Chiba K., Boroevich K.A., Abe T., Kawakami Y., Ueno M., Gotoh K., Ariizumi S., Shibuya T., Nakano K., Sasaki A., Maejima K., Kitada R., Hayami S., Shigekawa Y., Marubashi S., Yamada T., et al.
    • Journal Title

      PLoS One

      Volume: 9 Pages: e114263

    • DOI

      10.1371/journal.pone.0114263

    • Peer Reviewed
  • [Journal Article] Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation2014

    • Author(s)
      Sinner, M.F., Tucker N.R., Lunetta K.L., Ozaki K., Smith J.G., Trompet S., Bis J.C., Lin H., Chung M.K., Nielsen J.B., Lubitz S.A., Krijthe B.P., Magnani J.W., Ye J., Tsunoda T., Kubo M., Ebana Y., Furukawa T., Isobe M., Tanaka T., et al.
    • Journal Title

      Circulation

      Volume: 130 Pages: 1225-1235

    • DOI

      10.1161/CIRCULATIONAHA.114.009892

    • Peer Reviewed
  • [Journal Article] Subtypes of metabolic syndrome and of other risk factors in Japanese women with erosive esophagitis2014

    • Author(s)
      Sogabe, M., Okahisa T., Yamanoi A. and Takayama T.
    • Journal Title

      Medicine (Baltimore)

      Volume: 93 Pages: e276

    • DOI

      10.1097/MD.0000000000000276

    • Peer Reviewed
  • [Journal Article] TCGA output and practice of gastric cancer2014

    • Author(s)
      Sugimura, H
    • Journal Title

      Translational Gastrointestinal Cancer

    • Description
      Publish Ahead of Print
    • Peer Reviewed
  • [Journal Article] Counts of Slackia sp. strain NATTS in intestinal flora are correlated to serum concentrations of equol both in prostate cancer cases and controls in Japanese men2014

    • Author(s)
      Sugiyama, Y., Nagata Y., Fukuta F., Takayanagi A., Masumori N., Tsukamoto T., Akasaka H., Ohnishi H., Saito S., Miura T., Moriyama K., Tsuji H., Akaza H. and Mori M.
    • Journal Title

      Asian Pac J Cancer Prev

      Volume: 15 Pages: 2693-2697

    • Peer Reviewed
  • [Journal Article] A rare Japanese case with a NUT midline carcinoma in the nasal cavity : a case report with immunohistochemical and genetic analyses2014

    • Author(s)
      Suzuki, S., Kurabe N., Minato H., Ohkubo A., Ohnishi I., Tanioka F. and Sugimura H.
    • Journal Title

      Pathol Res Pract

      Volume: 210 Pages: 383-388

    • DOI

      10.1016/j.prp.2014.01.013

    • Peer Reviewed
  • [Journal Article] NSD3-NUT-expressing midline carcinoma of the lung : First characterization of primary cancer tissue2014

    • Author(s)
      Suzuki, S., Kurabe N., Ohnishi I., Yasuda K., Aoshima Y., Naito M., Tanioka F. and Sugimura H.
    • Journal Title

      Pathol Res Pract

    • DOI

      10.1016/j.prp.2014.10.013

    • Description
      Epub ahead of print
    • Peer Reviewed
  • [Journal Article] Extensive goblet cell metaplasia of the peripheral lung may harbor precancerous molecular changes : comparison of two cases2014

    • Author(s)
      Tajima, S., Kurabe N., Okudela K., Yajima K., Takahashi T., Neyatani H., Sugimura H. and Koda K.
    • Journal Title

      Pathol Int

      Volume: 64 Pages: 533-538

    • DOI

      10.1111/pin.12204

    • Peer Reviewed
  • [Journal Article] Radiation-induced breast angiosarcoma with a confirmative feature of c-MYC amplification2014

    • Author(s)
      Tajima, S., Mochizuki R., Sugimura H. and Hoshi S.
    • Journal Title

      Jpn J Clin Oncol

      Volume: 44 Pages: 702-703

    • DOI

      10.1093/jjco/hyu064

    • Peer Reviewed
  • [Journal Article] Advances in cancer epidemiology in Japan2014

    • Author(s)
      Tanaka, H.
    • Journal Title

      Int J Cancer

      Volume: 134 Pages: 747-754

    • DOI

      10.1002/ijc.28519

    • Peer Reviewed
  • [Journal Article] The biochemical recurrence-free rate in patients who underwent prostate low-dose-rate brachytherapy, using two different definitions2014

    • Author(s)
      Tanaka, N., Asakawa I., Katayama E., Hirayama A., Hasegawa M., Konishi N. and Fujimoto K.
    • Journal Title

      Radiat Oncol

      Volume: 9 Pages: 107

    • DOI

      10.1186/1748-717X-9-107

    • Peer Reviewed
  • [Journal Article] Use of alpha-1 adrenoceptor antagonists in patients who underwent low-dose-rate brachytherapy for prostate cancer-a randomized controlled trial of silodosin versus naftopidil2014

    • Author(s)
      Tanaka, N., Torimoto K., Asakawa I., Miyake M., Anai S., Hirayama A., Hasegawa M., Konishi N. and Fujimoto K.
    • Journal Title

      Radiat Oncol

      Volume: 9 Pages: 1163

    • DOI

      10.1186/s13014-014-0302-7

    • Peer Reviewed
  • [Journal Article] Nadir PSA level and time to nadir PSA are prognostic factors in patients with metastatic prostate cancer2014

    • Author(s)
      Tomioka, A., Tanaka N., Yoshikawa M., Miyake M., Anai S., Chihara Y., Okajima E., Hirayama A., Hirao Y. and Fujimoto K.
    • Journal Title

      BMC Urol

      Volume: 14 Pages: 33

    • DOI

      10.1186/1471-2490-14-33

    • Peer Reviewed
  • [Journal Article] Utility of PAX8 mouse monoclonal antibody in the diagnosis of thyroid, thymic, pleural and lung tumours : a comparison with polyclonal PAX8 antibody2014

    • Author(s)
      Toriyama, A., Mori T., Sekine S., Yoshida A., Hino O. and Tsuta K.
    • Journal Title

      Histopathology

      Volume: 65 Pages: 465-472

    • DOI

      10.1111/his.12405

    • Peer Reviewed
  • [Journal Article] Body mass index and breast cancer risk in Japan : a pooled analysis of eight population-based cohort studies2014

    • Author(s)
      Wada, K., Nagata C., Tamakoshi A., Matsuo K., Oze I., Wakai K., Tsuji I., Sugawara Y., Mizoue T., Tanaka K., Iwasaki M., Inoue M., Tsugane S., Sasazuki S., Research Group for the D. and Evaluation of Cancer Prevention Strategies in Japan
    • Journal Title

      Ann Oncol

      Volume: 25 Pages: 519-524

    • DOI

      10.1093/annonc/mdt542

    • Peer Reviewed
  • [Journal Article] Sugars, sucrose and colorectal cancer risk : the Fukuoka colorectal cancer study2014

    • Author(s)
      Wang, Z., Uchida K., Ohnaka K., Morita M., Toyomura K., Kono S., Ueki T., Tanaka M., Kakeji Y., Maehara Y., Okamura T., Ikejiri K., Futami K., Maekawa T., YasunamiY., Takenaka K., Ichimiya H. and Terasaka R.
    • Journal Title

      Scand J Gastroenterol

      Volume: 49 Pages: 581-588

    • DOI

      10.3109/00365521.2013.822091

    • Peer Reviewed
  • [Journal Article] Imputation and subset-based association analysis across different cancertypes identifies multiple independent risk loci in the TERT-CLPTMIL region onchromosome 5p15.332014

    • Author(s)
      Wang, Z., Zhu B., Zhang M., Parikh H., Jia J., Chung C.C., Sampson J.N., Hoskins J.W., Hutchinson A., Burdette L., Ibrahim A., Ito H., Kitahara C.M., Kohno T., Kunitoh H., Matsuo K., Niwa S., Shiraishi K., Tanaka H., Yatabe Y., et al.
    • Journal Title

      Hum Mol Genet

      Volume: 23 Pages: 6616-6633

    • DOI

      10.1093/hmg/ddu363

    • Peer Reviewed
  • [Journal Article] Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index2014

    • Author(s)
      Wen, W., Zheng W., Okada Y., Takeuchi F., Tabara Y., Hwang J.Y., Dorajoo R., Li H., Tsai F.J., Kubo M., Yamamoto K., Ohkubo T., Tsunoda T., Akiyama K., Takashima N., Isomura M., Umemura S., Isono M., Takayanagi R., Kang D.H., et al.
    • Journal Title

      Hum Mol Genet

      Volume: 23 Pages: 5492-5504

    • DOI

      10.1093/hmg/ddu248

    • Peer Reviewed
  • [Journal Article] Sexy Small Copy Numbers in Hereditary Gastric Carcinogenesis2014

    • Author(s)
      Yamada, H., Sakamoto H. and Sugimura H.
    • Journal Title

      J of Gastrointestinal & Digestive System

      Volume: 4 Pages: 205

    • DOI

      10.4172/2161-069X.1000205

    • Peer Reviewed
  • [Journal Article] A rare polymorphic variant of NBS1 reduces DNA repair activity and elevates chromosomal instability2014

    • Author(s)
      Yamamoto, Y., Miyamoto M., Tatsuda D., Kubo M., Nakagama H., Nakamura Y., Satoh H., Matsuda K., Watanabe T. and Ohta T.
    • Journal Title

      Cancer Res

      Volume: 74 Pages: 3707-3715

    • DOI

      10.1158/0008-5472.CAN-13-3037

    • Peer Reviewed
  • [Journal Article] Generation of human induced pluripotent stem (Ips) cells in serum- and feeder-free defined culture and TGF-Betal regulation of pluripotency2014

    • Author(s)
      Yamasaki, S., Taguchi Y., Shimamoto A., Mukasa H., Tahara H. and Okamoto T.
    • Journal Title

      PLoS One

      Volume: 9 Pages: e87151

    • DOI

      10.1371/journal.pone.0087151

    • Peer Reviewed
  • [Journal Article] Activation of Rheb, but not of mTORC1, impairs spine synapse morphogenesis in tuberous sclerosis complex2014

    • Author(s)
      Yasuda, S., Sugiura H., Katsurabayashi S., Shimada T., Tanaka H., Takasaki K., Iwasaki K., Kobayashi T., Hino O. and Yamagata K.
    • Journal Title

      Sci Rep

      Volume: 4 Pages: 5155

    • DOI

      10.1038/srep05155

    • Peer Reviewed
  • [Journal Article] Decreased amyloid-beta Pathologies by intracerebral loading of glycosphingolipid-enriched exosomes in Alzheimer model mice2014

    • Author(s)
      Yuyama, K., Sun H., Sakai S., Mitsutake S., Okada M., Tahara H., Furukawa J., Fujitani N., Shinohara Y. and Igarashi Y.
    • Journal Title

      J Biol Chem

      Volume: 289 Pages: 24488-24498

    • DOI

      10.1074/jbc.M114.577213

    • Peer Reviewed
  • [Journal Article] Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk2014

    • Author(s)
      Zhang, B., Jia W.H., Matsuda K., Kweon S.S., Matsuo K., Xiang Y.B., Shin A., Jee S.H., Kim D.H., Cai Q., Long J., Shi J., Wen W., Takahashi A., Matsuda F., Genetics, Epidemiology of Colorectal Cancer Consortium, Colorectal Transdisciplinary Study, Colon Cancer Family Registry, Hosono S., et al.
    • Journal Title

      Nat Genet

      Volume: 46 Pages: 533-542

    • DOI

      10.1038/ng.2985

    • Peer Reviewed
  • [Journal Article] Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians2014

    • Author(s)
      Zhang, B., Jia W.H., Matsuo K., Shin A., Xiang Y.B., Matsuda K., Jee S.H., Kim D.H., Cheah P.Y., Ren Z., Cai Q., Long J., Shi J., Wen W., Yang G., Ji B.T., Pan Z.Z., Matsuda F., Kubo M., Hosono S., et al.
    • Journal Title

      Int J Cancer

      Volume: 135 Pages: 948-955

    • DOI

      10.1002/ijc.28733

    • Peer Reviewed
  • [Journal Article] Burden of total and cause-specific mortality related to tobacco smoking among adults aged ≥ 45 years in Asia : a pooled analysis of 21 cohorts2014

    • Author(s)
      Zheng, W., McLerran D.F., Rolland B.A., Fu Z., Boffetta P., Tsugane S., Irie F., Tamakoshi A., Shu X.O., Ozasa K., Nishino Y., Tsuji I., Tanaka H., Sawada N., Ohishi W., Kakizaki M., Watanabe T., Oze I., Sugawara Y., Matsuo K., et al.
    • Journal Title

      PLoS Med

      Volume: 11 Pages: e1001631

    • DOI

      10.1371/journal.Pmed.1001631

    • Peer Reviewed
  • [Journal Article] クルクミンによるaryl hydrocarbon receptor(AhR)を介した発癌抑制機構2014

    • Author(s)
      井手久満、陸彦、杉浦正一郎、堀内明、古謝将之、中島晶子、井上正浩、野間康央、北村香介、常盤紫野、斎藤恵介、吉井隆、磯谷周治、山口雷藏、武藤智、堀江重郎
    • Journal Title

      日本腎泌尿器科疾患予防医学研究会誌

      Volume: 22 Pages: 35-37

  • [Journal Article] 統計家の行動基準の策定-背景と今後の課題2014

    • Author(s)
      佐藤恵子、岩崎学、菅波秀規、佐藤俊哉、椿広計
    • Journal Title

      計量生物学

      Volume: 35 Pages: 37-53

    • DOI

      10.5691/jjb.35.37

    • Peer Reviewed
  • [Journal Article] バイオバンクにおける同意撤回の自由と不帰投点(Point of No Return)2014

    • Author(s)
      松井健志、會澤久仁子、玉腰暁子
    • Journal Title

      臨床薬理

      Volume: 45 Pages: 17-23

    • DOI

      10.3999/jscpt.45.17

    • Peer Reviewed
  • [Journal Article] 前立腺癌におけるがん幹細胞研究(特集去勢抵抗性前立腺癌 : 基礎と臨床の最新研究動向)--(前立腺癌の最新情報)2014

    • Author(s)
      西田幸代、舛森直哉
    • Journal Title

      日本臨床

      Volume: 72 Pages: 2229-2233

  • [Journal Article] バイオバンク2014

    • Author(s)
      増井徹
    • Journal Title

      シリーズ生命倫理学

      Volume: 11「遺伝子と医療」 Pages: 188-203

    • Description
      (丸善出版)
  • [Journal Article] ヒトゲノム研究の規制について : ゲノム情報の利用に焦点をあてて2014

    • Author(s)
      増井徹
    • Journal Title

      Organ Biology

      Volume: 21 Pages: 16-23

    • DOI

      10.11378/organbio.21.16

  • [Journal Article] 遺伝子診断の未来と罠2014

    • Author(s)
      増井徹、齋藤加代子、菅野純夫
    • Journal Title

      こころの科学

      Volume: 増刊 Pages: 1-156

    • Description
      (日本評論社)
  • [Journal Article] 日本人閉経女性における肥満と骨質に関する検討(第15回日本骨粗鬆症学会)2014

    • Author(s)
      尾崎悦子、栗山長門、松井大輔
    • Journal Title

      オステオポローシスジャパン : 日本骨粗鬆症学会雑誌

      Volume: 22 Pages: 465-468

    • Peer Reviewed
  • [Journal Article] HTLV-1 induces a Thl-like state in CD4+CCR4+T cells2014

    • Author(s)
      N. Araya, T. Sato, H. Ando, U. Tomaru, M. Yoshida, A. Coler-Reilly, N. Yagishita, J. Yamauchi, A. Hasegawa, M. Kannagi, Y. Hasegawa, K. Takahashi, Y. Kunitomo, Y. Tanaka, T. Nakajima, K. Nishioka, A. Utsunomiya, S. Jacobson, Y. Yamano
    • Journal Title

      J Clin Invest

      Volume: 124 Issue: 8 Pages: 3431-42

    • DOI

      10.1172/JCI75250

    • Peer Reviewed
  • [Journal Article] Antitumor effects of bevacizumab in a microenvironment-dependent human adult T-cell leukemia/lymphoma mouse model2014

    • Author(s)
      Mori, F., Ishida, T., Ito, A., Sato, F., Masaki, A., Narita, T., Suzuki, S., Yamada, T., Takino, H., Ri, M., Kusumoto, S., Komatsu, H., Hishizawa, M., Imada, K., Takaori-Kondo, A., Niimi, A., Ueda, R., Inagaki, H. & Iida, S.
    • Journal Title

      European journal of haematology

      Volume: 92 Pages: 219-228

    • DOI

      10.1111/ejh.12231

    • Peer Reviewed
  • [Journal Article] Reactivation of hepatitis B virus in a patient with adult T-cell leukemia-lymphoma receiving the anti-CC chemokine receptor 4 antibody mogamulizumab2014

    • Author(s)
      Nakano, N., Kusumoto, S., Tanaka, Y., Ishida, T., Takeuchi, S., Takatsuka, Y., Akinaga, S., Mizokami, M., Ueda, R. & Utsunomiya, A.
    • Journal Title

      Hepatology research : the official journal of the Japan Society of Hepatology

      Volume: 44 Pages: 354-357

    • DOI

      10.1111/hepr.12117

    • Peer Reviewed
  • [Journal Article] HTLV-1 bZIP factor-specific CD4 T cell responses in adult T cell leukemia/lymphoma patients after allogeneic hematopoietic stem cell transplantation2014

    • Author(s)
      Narita, T., Ishida, T., Masaki, A., Suzuki, S., Ito, A., Mori, F., Yamada, T., Ri, M., Kusumoto, S., Komatsu, H., Miyazaki, Y., Takatsuka, Y., Utsunomiya, A., Niimi, A., Iida, S. & Ueda, R.
    • Journal Title

      Journal of immunology

      Volume: 192 Pages: 940-947

    • DOI

      10.4049/jimmunol.1301952

    • Peer Reviewed
  • [Journal Article] Prognostic impact of microRNA-145 down-regulation in adult T-cell leukemia/lymphoma2014

    • Author(s)
      Xia, H., Yamada, S., Aoyama, M., Sato, F., Masaki, A., Ge, Y., Ri, M., Ishida, T., Ueda, R., Utsunomiya, A., Asai, K. & Inagaki, H.
    • Journal Title

      Human pathology

      Volume: 45 Pages: 1192-1198

    • DOI

      10.1016/j.humpath.2014.01.017

    • Peer Reviewed
  • [Journal Article] HTLV-1 proviral integration sites differ between asymptomatic carriers and patients with HAM/TSP2014

    • Author(s)
      Niederer HA, Laydon DJ, Melamed A, Elemans M, Asquith B, Matsuoka M, Bangham CR
    • Journal Title

      Virology J

      Volume: 11 Pages: 172

    • DOI

      10.1186/1743-422X-11-172

    • Peer Reviewed
  • [Journal Article] A critical role for IL-17RB signaling in HTLV-1 Tax-induced NF-κB activation and T-cell transformation2014

    • Author(s)
      Lavorgna A, Matsuoka M, Harhaj EW
    • Journal Title

      PLoS Pathogens

      Volume: 10 Pages: e1004418

    • DOI

      10.1371/journal.ppat.1004418

    • Peer Reviewed
  • [Journal Article] The role of HTLV-1 clonality, proviral structure and genomic integration site in adult T cell leukemia/lymphoma2014

    • Author(s)
      Cook LB, Melamed A, Niederer H, Valganon M, Laydon D, Foroni L, Taylor GP, Matsuoka M, Bangham CR
    • Journal Title

      Blood

      Volume: 123 Pages: 3925-3931

    • DOI

      10.1182/blood-2014-02-553602

    • Peer Reviewed
  • [Journal Article] Development of T cell lymphoma in HTLV-1 bZIP factor and Tax double transgenic mice2014

    • Author(s)
      Zhao, T, Satou Y and Matsuoka M
    • Journal Title

      Arch Virol

      Volume: 159 Pages: 1849-1856

    • DOI

      10.1007/s00705-014-2099-y

    • Peer Reviewed
  • [Journal Article] Controlling leucine-zipper partner recognition in cells through modifications of a-g interactions2014

    • Author(s)
      Azuma Y, Kukenshöner T, Ma G, Yasunaga JI, Imanishi M, Arndt KM, Matsuoka M, and Futaki S
    • Journal Title

      Chem. Commun.

      Volume: 50 Pages: 6364-6367

    • DOI

      10.1039/c4cc00555d

    • Peer Reviewed
  • [Journal Article] HTLV-1 bZIP factor suppresses apoptosis by attenuating the function of Fox03a and altering its localization2014

    • Author(s)
      Tanaka-Nakanishi A, Yasunaga J-I, Takai K and Matsuoka M
    • Journal Title

      Cancer Res

      Volume: 74 Pages: 188-200

    • DOI

      10.1158/0008-5472.CAN-13-0436

    • Peer Reviewed
  • [Journal Article] Human T-cell leukemia virus type 1 and Foxp3 expression : viral strategy in vivo2014

    • Author(s)
      Miyazato P and Matsuoka M
    • Journal Title

      Int Immunol

      Volume: 26 Pages: 419-425

    • DOI

      10.1093/intimm/dxu048

    • Peer Reviewed
  • [Journal Article] Cytotoxic T lymphocyte lysis of HTLV-1 infected cells is limited by weak HBZ protein expression, but non-specifically enhanced on induction of Tax expression2014

    • Author(s)
      Rowan AG, Suemori K, Fujiwara H, Yasukawa M, Tanaka Y, Taylor GP, Bangham C
    • Journal Title

      Retrovirology

      Volume: 11 Issue: 1 Pages: 116

    • DOI

      10.1186/s12977-014-0116-6

    • Peer Reviewed
  • [Journal Article] Downregulation of proapoptotic Bim augments IL-2-independent T-cell transformation by human T-cell leukemia virus type-1 Tax2014

    • Author(s)
      Higuchi M, Takahashi M, Tanaka Y, Fujii M
    • Journal Title

      Cancer Med

      Volume: 3 Issue: 6 Pages: 1605-14

    • DOI

      10.1002/cam4.329

    • Peer Reviewed
  • [Journal Article] The neutralizing function of the anti-HTLV-1 antibody is essential in preventing in vivo transmission of HTLV-1 to human T cells in NOD-SCID/gammac null (NOG) mice2014

    • Author(s)
      Saito M, Tanaka R, Fujii H, Kodama A, Takahashi Y, Matsuzaki T, Takashima H, Tanaka Y
    • Journal Title

      Retrovirology

      Volume: 11 Issue: 1 Pages: 74

    • DOI

      10.1186/s12977-014-0074-z

    • Peer Reviewed
  • [Journal Article] Epigenetic deregulation of Ellis Van Creveld confers robust Hedgehog signaling in adult T-cell leukemia2014

    • Author(s)
      Takahashi R, Yamagishi M, Nakano K, Yamochi T, Yamochi T, Fujikawa D, Nakashima M, Tanaka Y, Uchimaru K, Utsunomiya A, Watanabe T
    • Journal Title

      Cancer Sci

      Volume: 105 Issue: 9 Pages: 1160-9

    • DOI

      10.1111/cas.12480

    • Peer Reviewed
  • [Journal Article] Epigenetic modification of the FoxP3 TSDR in HAM/TSP decreases the functional suppression of Tregs2014

    • Author(s)
      Anderson MR, Enose-Akahata Y, Massoud R, Ngouth N, Tanaka Y, Oh U, Jacobson S
    • Journal Title

      J Neuroimmune Pharmacol

      Volume: 9 Issue: 4 Pages: 522-32

    • DOI

      10.1007/s11481-014-9547-z

    • Peer Reviewed
  • [Journal Article] Elimination of human T cell leukemia virus type-l-infected cells by neutralizing and antibody-dependent cellular cytotoxicity-inducing antibodies against human t cell leukemia virus type-1 envelope gp462014

    • Author(s)
      Tanaka Y, Takahashi Y, Tanaka R, Kodama A, Fujii H, Hasegawa A, Kannagi M, Ansari AA, Saito M
    • Journal Title

      AIDS Res Hum Retroviruses

      Volume: 30 Issue: 6 Pages: 542-52

    • DOI

      10.1089/AID.2013.0214

    • Peer Reviewed
  • [Journal Article] HTLV-1キャリアが産生するウイルス構造蛋白質に対する抗体と末梢血中のプロウイルス量に関する解析2014

    • Author(s)
      井上由紀子, 守田麻衣子, 後藤信代, 相良康子, 入田和男, 矢持忠徳, 渡邉俊樹, 岩永正子, 浜口功, 清川博之
    • Journal Title

      日本輸血細胞治療学会誌

      Volume: 60 Issue: 6 Pages: 592-599

    • Peer Reviewed
  • [Journal Article] Development and validation of a new high-throughput method to investigate the clonality of HTLV-l-infected cells based on provirus integration sites2014

    • Author(s)
      Firouzi S, Lopez Y, Suzuki Y, Nakai K, Sugano S, Yamochi T, Watanabe T
    • Journal Title

      Genome Med

      Volume: 6 Issue: 6 Pages: 46

    • DOI

      10.1186/gm568

    • Peer Reviewed
  • [Journal Article] CADM1 expression and stepwise downregulation of CD7 are closely associated with clonal expansion of HTLV-1-infected cells in adult T-cell leukemia/lymphoma2014

    • Author(s)
      Kobayashi S, Nakano K, Watanabe E, Ishigaki T, Ohno N, Yuji K, Oyaizu N, Asanuma S, Yamagishi M, Yamochi T, Watanabe N, Tojo A, Watanabe T, Uchimaru K
    • Journal Title

      Clin Cancer Res

      Volume: 20 Issue: 11 Pages: 2851-2861

    • DOI

      10.1158/1078-0432.CCR-13-3169

    • Peer Reviewed
  • [Journal Article] High level of serum soluble interleukin-2 receptor at transplantation predicts poor outcome of allogeneic stem cell transplantation for adult T-cell leukemia2014

    • Author(s)
      Shigematsu A, Kobayashi N, Yasui H, Shindo M, Kakinoki Y, Koda K, Iyama S, Kuroda H, Tsutsumi Y, Imamura M, Teshima T
    • Journal Title

      Biol Blood Marrow Transplant

      Volume: 20 Pages: 801-805

    • DOI

      10.1016/j.bbmt.2014.02.014

    • Peer Reviewed
  • [Journal Article] Epstein-Barr virus-infected cells in IgG4-related lymphadenopathy with comparison to extranodal IgG4-related disease2014

    • Author(s)
      Takeuchi M, Sato Y, Yasui H, Ozawa H, Ohno K, Takata K, Iwaki N, Orita Y, Asano N, Nakamura S, Swerdlow SH, Yoshino T
    • Journal Title

      Am J Surg Pathol

      Volume: 38 Pages: 946-955

    • DOI

      10.1097/PAS.0000000000000206

    • Peer Reviewed
  • [Journal Article] Cancer-associated fibroblast-targeted strategy enhances antitumor immune responses in the dendritic cell-based vaccine2014

    • Author(s)
      Ohshio Y, Teramoto K, Hanaoka J, Tezuka N, Itoh Y, Asai T, Daigo Y, Ogasawara K
    • Journal Title

      Cancer Sci

    • DOI

      10.1111/cas.12584

    • Description
      [Epub ahead of print]
    • Peer Reviewed
  • [Journal Article] Clinicopathological features and EGFR gene mutation status in elderly patients with resected non-small-cell lung cancer2014

    • Author(s)
      Nishii T, Yokose T, Miyagi Y, Daigo Y, Ito H, Isaka T, Imai K, Murakami S, Kondo T, Saito H, Oshita F, Yamada K, Matsukuma S, Tsuboi M, Nakayama H, Masuda M
    • Journal Title

      BMC Cancer

      Volume: 14 Pages: 610

    • DOI

      10.1186/1471-2407-14-610

    • Peer Reviewed
  • [Journal Article] Identification of a nuclear protein LRRC42 involved in lung pulmonary carcinogenesis2014

    • Author(s)
      Fujitomo T, Daigo Y, Matsuda K, Ueda K, Nakamura Y
    • Journal Title

      Int J Oncol

      Volume: 45 Pages: 147-56

    • DOI

      10.3892/ijo.2014.2418

    • Peer Reviewed
  • [Journal Article] Identification of immunogenic LY6K long peptide encompassing both CD4+ and CD8+ T-cell epitopes and eliciting CD4+ T-cell immunity in patients with malignant disease2014

    • Author(s)
      Tomita Y, Yuno A, Tsukamoto H, Senju S, Kuroda Y, Hirayama M, Imamura Y, Yatsuda J, Mohammad Abu Sayem, Irie A, Hamada A, Jono H, Yoshida K, Tsunoda T, Daigo Y, Kohrogi H, Yoshitake Y, Nakamura Y, Shinohara M, Nishimura Y.
    • Journal Title

      Oncoimmunology

      Volume: 3 Pages: e28100

    • DOI

      10.4161/onci.28100

    • Peer Reviewed
  • [Journal Article] Cell division cycle-associated protein 1 overexpression is essential for the malignant potential of colorectal cancers.2014

    • Author(s)
      Kobayashi Y, Takano A, Miyagi Y, Tsuchiya E, Sonoda H, Shimizu T, Okabe H, Tani T, Fujiyama Y, Daigo Y.
    • Journal Title

      Int J Oncol

      Volume: 44 Pages: 69-77

    • DOI

      10.3892/ijo.2013.2177

    • Peer Reviewed
  • [Journal Article] Proteomic Analysis of Proteins Related to Prognosis of Lung Adenocarcinoma.2014

    • Author(s)
      Okayama A, Miyagi Y, Oshita F, Nishi M, Nakamura Y, Nagashima Y, Akimoto K, Ryo A, Hirano H.
    • Journal Title

      J Proteome Res

      Volume: 13 Issue: 11 Pages: 4686-94

    • DOI

      10.1021/pr4012969

    • Peer Reviewed
  • [Journal Article] SIRT1 expression is associated with a poor prognosis, whereas DBC1 is associated with favorable outcomes in gastric cancer2014

    • Author(s)
      Noguchi A, Kikuchi K, Zheng H, Takahashi H, Miyagi Y, Aoki I, Takano Y.
    • Journal Title

      Cancer Med

      Volume: 3 Issue: 6 Pages: 1553-61

    • DOI

      10.1002/cam4.310

    • Peer Reviewed
  • [Journal Article] Angiomodulin, a marker of cancer vasculature, is upregulated by vascular endothelial growth factor and increases vascular permeability as a ligand of integrin αvβ32014

    • Author(s)
      Komiya E, Sato H, Watanabe N, Ise M, Higashi S, Miyagi Y, Miyazaki K
    • Journal Title

      Cancer Med

      Volume: 3 Issue: 3 Pages: 537-49

    • DOI

      10.1002/cam4.216

    • Peer Reviewed
  • [Journal Article] Lung adenocarcinoma subtypes definable by lung development-related miRNA expression profiles in association with clinicopathologic features2014

    • Author(s)
      Arima C, Kajino T, Tamada Y, Imoto S, ShimadaY, Nakatochi, M, Suzuki M, Isomura H, Yatabe Y, Yamaguchi T, Yanagisawa K, Miyano S, Takahashi T.
    • Journal Title

      Carcinogenesis

      Volume: 35 Pages: 2224-2231

    • DOI

      10.1093/carcin/bgu127

    • Peer Reviewed
  • [Journal Article] Expression of chromobox homolog 7 (CBX7) is associated with poor prognosis in ovarian clear cell adenocarcinoma via TRAIL-induced apoptotic pathway regulation.2014

    • Author(s)
      Shinjo K, Yamashita Y, Yamamoto E, Akatsuka S, Uno N, Kamiya A, Niimi K, Sakaguchi Y, Nagasaka T, Takahashi T, Shibata K, Kajiyama H, Kikkawa F, Toyokuni S.
    • Journal Title

      Int J Cancer

      Volume: 135 Pages: 308-318

    • DOI

      10.1002/ijc.28692

    • Peer Reviewed
  • [Journal Article] Tumor-derived Interleukin-1 promotes lymphangiogenesis and lymph node metastasis through M2-type macrophages2014

    • Author(s)
      Watari K, Shibata T, Kawahara A, Sata K, Nabeshima H, Shinoda A, Abe H, Azuma K, Murakami Y, Izumi, H, Takahashi T, Kage M, Kuwano M, Ono M.
    • Journal Title

      PLoS ONE

      Volume: 9 Pages: e999568

    • DOI

      10.1371/journal.pone.0099568

    • Peer Reviewed
  • [Journal Article] Cancer-promoting role of adipocytes in asbestos-induced mesothelial carcinogenesis through dysregulated adipocytokine production2014

    • Author(s)
      Chew SH, Okazaki Y, Nagai H, Misawa N, Akatsuka S, Yamashita K, Jiang L, Yamashita Y, Noguchi M, Hosoda K, Sekido Y, Takahashi T, Toyokuni S
    • Journal Title

      Carcinogenesis

      Volume: 35 Pages: 164-172

    • DOI

      10.1093/carcin/bgt267

    • Peer Reviewed
  • [Journal Article] Multimodal Effects of Small Molecule ROCK and LIMK Inhibitors on Mitosis, and Their Implication as Anti-Leukemia Agents2014

    • Author(s)
      Oku Y, Tareyanagi C, Takaya S, Osaka S, Ujiie H, Yoshida K, Nishiya N, Uehara Y.
    • Journal Title

      PLoS One

      Volume: 9 Pages: e92402

    • DOI

      10.1371/journal.pone.0092402

    • Peer Reviewed
  • [Journal Article] A zebrafish chemical suppressor screening identifies small molecule inhibitors of the Wnt/β-catenin pathway2014

    • Author(s)
      Nishiya N, Oku Y, Kumagai Y, Sato Y, Yamaguchi E, Sasaki A, Shoji M, Ohnishi Y, Okamoto H, Uehara Y.
    • Journal Title

      Chemistry & Biology

      Volume: 12 Pages: 530-540

    • DOI

      10.1016/j.chembiol.2014.02.015

    • Peer Reviewed
  • [Journal Article] Total synthesis of burkholdacs A and B and 5, 6, 20-tri-epi-burkholdac A : HDAC inhibition and antiproliferative activity2014

    • Author(s)
      Fukui Y, Narita K, Dan S, Yamori T, Ito A, Yoshida M, Katoh T
    • Journal Title

      Eur. J. Med. Chem.

      Volume: 76 Pages: 301-313

    • DOI

      10.1016/j.ejmech.2014.02.044

    • Peer Reviewed
  • [Journal Article] 5-Lipoxygenase and CysLTl regulate EGF-induced cell migration through Tiaml upregulation and Racl activation2014

    • Author(s)
      Magi S, Takemoto Y, Kobayashi H, Kasamatsu M, Akita T, Tanaka A, Takano K, Tashiro E, Igarashi Y, Imoto M
    • Journal Title

      Cancer Sci

      Volume: 105 Pages: 290-296

    • DOI

      10.1111/cas.12340

    • Peer Reviewed
  • [Journal Article] TRIBl supports prostate tumorigenesis and tumor-propagating cell survival by regulation of endoplasmic reticulum chaperone expression2014

    • Author(s)
      Mashima T, Soma-Nagae T, Migita T, Kinoshita R, Iwamoto A, Yuasa T, Yonese J, Ishikawa Y, Seimiya H
    • Journal Title

      Cancer Res

      Volume: 74 Pages: 4888-4897

    • DOI

      10.1158/0008-5472.CAN-13-3718

    • Peer Reviewed
  • [Journal Article] Inhibition of ATP citrate lyase induces triglyceride accumulation with altered fatty acid composition in cancer cells2014

    • Author(s)
      Migita T, Okabe S, Ikeda K, Igarashi S, Sugawara S, Tomida A, Soga T, Taguchi R, Seimiya H
    • Journal Title

      Int J Cancer

      Volume: 135 Pages: 37-47

    • DOI

      10.1002/ijc.28652

    • Peer Reviewed
  • [Journal Article] Xanthohumol suppresses oestrogen-signalling in breast cancer through the inhibition of BIG3-PHB2 interactions2014

    • Author(s)
      Yoshimaru T, Komatsu M, Tashiro E, Imoto M, Osada H, Miyoshi Y, Honda J, Sasa M, Katagiri T
    • Journal Title

      Sci Rep

      Volume: 4 Pages: 7355

    • DOI

      10.1038/srep07355

    • Peer Reviewed
  • [Journal Article] A small compound targeting TACC3 revealed its different spatiotemporal contributions for spindle assembly in cancer cells2014

    • Author(s)
      Yao R, Kondoh Y, Natsume Y, Yamanaka H, Inoue M, Toki H, Takagi R, Shimizu T, Yamori T, Osada H, Noda T
    • Journal Title

      Oncogene

      Volume: 33 Issue: 33 Pages: 4242-4252

    • DOI

      10.1038/onc.2013.382

    • Peer Reviewed
  • [Journal Article] Regulation of Tissue Factor Pathway Inhibitor-2 (TFPI-2) Expression by Lysine-Specific Demethylase 1 and 2 (LSD1 and LSD2)2014

    • Author(s)
      Mino K, Nishimura S, Ninomiya S, Tujii H, Matsumori Y, Tsuchida M, Hosoi M, Koseki K, Wada S, Hasegawa M, Sasaki R, Murakami-Yamaguchi Y, Narita H, Suzuki T, Miyata N, Mizukami T
    • Journal Title

      Biosci Biotechnol Biochem

      Volume: 78 Issue: 6 Pages: 1010-1017

    • DOI

      10.1080/09168451.2014.910104

    • Peer Reviewed
  • [Journal Article] Array-based genome-wide RNAi screening to identify shRNAs that enhance p53-related apoptosis in human cancer cells2014

    • Author(s)
      Idogawa M, Ohashi T, Sugisaka J, Sasaki Y, Suzuki H, Tokino T
    • Journal Title

      Oncotarget

      Volume: 5 Issue: 17 Pages: 7540-7548

    • Peer Reviewed
  • [Journal Article] Forkhead transcription factor FOXF1 is a novel target gene of the p53 family and regulates cancer cell migration and invasiveness2014

    • Author(s)
      Tamura M, Sasaki Y, Koyama R, Takeda K, Idogawa M, Tokino T
    • Journal Title

      Oncogene

      Volume: 33 Issue: 40 Pages: 4837-4846

    • DOI

      10.1038/onc.2013.427

    • Peer Reviewed
  • [Journal Article] Identification and analysis of large non-coding RNAs regulated by p53 family members through a genome-wide analysis of p53-binding sites2014

    • Author(s)
      Idogawa M, Ohashi T, Sasaki Y, Maruyama R, Kashima L, Suzuki H, Tokino T
    • Journal Title

      Human Molecular Genetics

      Volume: 23 Issue: 11 Pages: 2847-2857

    • DOI

      10.1093/hmg/ddt673

    • Peer Reviewed
  • [Journal Article] Silencing of microRNA-122 is an early event during hepatocarcinogenesis from non-alcoholic steatohepatitis2014

    • Author(s)
      Takaki Y, Saito Y, Takasugi A, Toshimitsu K, Yamada S, Muramatsu T, Kimura M, Sugiyama K, Suzuki H, Arai E, Ojima H, Kanai Y, Saito H
    • Journal Title

      Cancer Sci

      Volume: 105 Pages: 1254-1260

    • DOI

      10.1111/cas.12498

    • Peer Reviewed
  • [Presentation] マイクロRNAを用いたバイオマーカーおよび核酸医薬の開発2015

    • Author(s)
      田原栄俊
    • Organizer
      第59回分子病態医学セミナー&TRCセミナー合同セミナー
    • Place of Presentation
      愛媛大学(愛媛県・松山市)
    • Year and Date
      2015-04-03
  • [Presentation] microRNAが切り拓く創薬研究の新展開について2015

    • Author(s)
      田原栄俊
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸学院大学(兵庫県・神戸市)
    • Year and Date
      2015-03-27
    • Invited
  • [Presentation] テロメア・マイクロRNAを用いた疾患の予防と早期診断2015

    • Author(s)
      田原栄俊
    • Organizer
      第40回日本脳卒中学会総会
    • Place of Presentation
      リーガロイヤルホテル広島(広島県・広島市)
    • Year and Date
      2015-03-27
    • Invited
  • [Presentation] Clock遺伝子多型と糖尿病有病との関連について : J-MICC Studyより2015

    • Author(s)
      上村浩一、山口美輪、釜野桜子、有澤孝吉、J-MICC Study Group
    • Organizer
      第85回日本衛生学会学術総会
    • Place of Presentation
      和歌山県民文化会館(和歌山県・和歌山市)
    • Year and Date
      2015-03-26 – 2015-03-28
  • [Presentation] 細菌型チロシンキナーゼ阻害剤探索系の開発2015

    • Author(s)
      深澤秀輔、益見厚子
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      兵庫医療大学(兵庫県・神戸市)
    • Year and Date
      2015-03-26
  • [Presentation] 遺伝子型cnmを有するS. mutans感染と脳内微小出血が関連する-歯科領域との新しい連携の可能性-2015

    • Author(s)
      栗山長門, 水野敏樹、山田恵、渡邊能行
    • Organizer
      第40回脳卒中学会
    • Place of Presentation
      リーガロイヤルホテル広島(広島県・広島市)
    • Year and Date
      2015-03-25
  • [Presentation] Circulating miRNAs as liquid biopsy in Alzheimer's disease and pancreatic cancer toward application for the diagnosis2015

    • Author(s)
      Yu Ninose, Sayaka Okamoto, Ikuko Takeda, Tetsuya Takahashi, Masayasu Matsumoto
    • Organizer
      Extracellular Biomarkers Summit
    • Place of Presentation
      Hyatt Regency Cambridge, Boston, U.S.A.
    • Year and Date
      2015-03-16
  • [Presentation] マイクロRNA・細胞外小胞がもたらす脳神経内科の未来2015

    • Author(s)
      田原栄俊
    • Organizer
      第13回脳神経内科ジョイントミーティング
    • Place of Presentation
      リーガロイヤルホテル広島(広島県・広島市)
    • Year and Date
      2015-03-03
    • Invited
  • [Presentation] 日本人non-CKDにおける血清FGF23濃度の決定因子と尿中アルブミン排泄(ACR)について」2015

    • Author(s)
      尾﨑悦子、稲葉雅章、山田真介、栗山長門、松井大輔、渡邉功、小山晃英、渡邊能行
    • Organizer
      第26回日本腎性骨症研究会
    • Place of Presentation
      品川プリンスホテル(東京)
    • Year and Date
      2015-02-21
  • [Presentation] 腎細胞癌肺転移新規モデルの構築及び評価2015

    • Author(s)
      三島胡桃、山野荘太郎、山田健二、藤岡正喜、魏民、鰐渕英機
    • Organizer
      第14回分子予防環境医学研究会
    • Place of Presentation
      大阪市立大学(大阪府・大阪市)
    • Year and Date
      2015-02-13 – 2015-02-14
  • [Presentation] 1,2-DCP投与によるハムスターおよびマウスの肝毒性メカニズムの検討2015

    • Author(s)
      下村衣里、魏民、藤岡正喜、山野荘太郎、梯アンナ、鰐渕英機
    • Organizer
      第14回分子予防環境医学研究会
    • Place of Presentation
      大阪市立大学(大阪府・大阪市)
    • Year and Date
      2015-02-13 – 2015-02-14
  • [Presentation] 成人T細胞白血病の成り立ちと免疫療法2015

    • Author(s)
      神奈木真理
    • Organizer
      第64回日本輸血・細胞治療学会東海支部例会
    • Place of Presentation
      桑山ビル(愛知県・名古屋市)
    • Year and Date
      2015-02-07
    • Invited
  • [Presentation] 腎発がんモデルを用いた発がん機構の解明及び転移モデルへの応用2015

    • Author(s)
      山野荘太郎、三島胡桃、山田健二、平山幸良、藤岡正喜、魏民、鰐渕英機
    • Organizer
      平成26年度「個体レベルでのがん研究支援活動」ワークショップ
    • Place of Presentation
      琵琶湖ホテル(滋賀県・大津市)
    • Year and Date
      2015-02-05 – 2015-02-06
  • [Presentation] 肝微小環境が及ぼす転移性腎癌への影響2015

    • Author(s)
      平山幸良、山野荘太郎、山田健二、藤岡正喜、魏民、三島胡桃、鰐渕英機
    • Organizer
      平成26年度「個体レベルでのがん研究支援活動」ワークショップ
    • Place of Presentation
      琵琶湖ホテル(滋賀県・大津市)
    • Year and Date
      2015-02-05 – 2015-02-06
  • [Presentation] 肺発がんの発育進展に関与する発がん促進・抑制作用について2015

    • Author(s)
      今井田克己
    • Organizer
      平成26年度「個体レベルでのがん研究支援活動」ワークショップ
    • Place of Presentation
      琵琶湖ホテル(大津市・滋賀県)
    • Year and Date
      2015-02-05 – 2015-02-06
    • Invited
  • [Presentation] ハムスターBOP二段階膵胆管発がんモデルを用いた1,2-dichloropropane(1,2-DCP)の発がん修飾作用の検討2015

    • Author(s)
      下村衣里、魏民、藤岡正喜、山野荘太郎、梯アンナ、鰐渕英機
    • Organizer
      第31回日本毒性病理学会学術総会及び学術集会
    • Place of Presentation
      タワーホール船堀(東京)
    • Year and Date
      2015-01-29 – 2015-01-30
  • [Presentation] CNPY2 and CACHD1 as novel molecular markers of hepatocellular carcinoma2015

    • Author(s)
      Anna Kakehashi, Naomi Ishii, Min Gi, Masaki Fujioka, Hideki Wanibuchi
    • Organizer
      第31回日本毒性病理学会学術総会及び学術集会
    • Place of Presentation
      タワーホール船堀(東京)
    • Year and Date
      2015-01-29 – 2015-01-30
  • [Presentation] 非遺伝毒性肝発がん物質ダンマル樹脂の発がんメカニズムの検討2015

    • Author(s)
      藤岡正喜、魏民、山野荘太郎、下村衣里、三島胡桃、鰐渕英機
    • Organizer
      第31回日本毒性病理学会学術総会及び学術集会
    • Place of Presentation
      タワーホール船堀(東京)
    • Year and Date
      2015-01-29 – 2015-01-30
  • [Presentation] ラット同所同種移植による新規腎癌肺転移モデルの確立及び評価2015

    • Author(s)
      三島胡桃、山野荘太郎、魏民、鰐渕英機
    • Organizer
      第31回日本毒性病理学会学術総会及び学術集会
    • Place of Presentation
      タワーホール船堀(東京)
    • Year and Date
      2015-01-29 – 2015-01-30
  • [Presentation] ハムスターBOP二段階膵胆管発がんモデルを用いた1,2-dichloropropane(1,2-DCP)の発がん修飾作用の検討2015

    • Author(s)
      下村衣里、魏民、藤岡正喜、山野荘太郎、梯アンナ、鰐渕英機
    • Organizer
      第31回日本毒性病理学会学術総会及び学術集会2015年1月29~30日タワーホール船堀(東京都)
    • Place of Presentation
      タワーホール船堀(東京)
    • Year and Date
      2015-01-29 – 2015-01-30
  • [Presentation] Comparison of dietary record procedures in calibration studies for two large cohort studies2015

    • Author(s)
      Imaeda N, Ishihara J, Takachi R, Goto C, Ishii Y, Kojima S, Nanri H, Nakamura K, Yamaguchi M, Tanaka J, Fukuda N, Iso H, Hosono S, Shimazu T, Miyagawa N, Sawada N, Wakai K, Sasazuki S, Tanaka H, Tsugane S
    • Organizer
      第25回日本疫学会学術総会
    • Place of Presentation
      ウインクあいち(愛知県・名古屋市)
    • Year and Date
      2015-01-23
  • [Presentation] ABCG2 gysfunction causes not only renal urate overload hyperuricemia but also renal-urate underexcretion hyperuricemia2015

    • Author(s)
      Matsuo H, Nakayama A, Sakiyama M, Chiba T, Shimazu S, Nakashima H, Nakamura T, Takada Y, Takada T, Nakaoka H, Wakai K, Kawai S, Tin G, Nakagawa H, Ito T, Yamamoto K, Sakurai Y, Ichida K, Shimizu T, Shinomiya N
    • Organizer
      第25回日本疫学会学術総会
    • Place of Presentation
      ウインクあいち(愛知県・名古屋市)
    • Year and Date
      2015-01-23
  • [Presentation] Genefic effect by dysfunctional variants of ABCG2 is tronger than environmental effects for hyperuricemia2015

    • Author(s)
      Nakayama A, Matsuo H, Nakaoka H, Nakamura T, Nakashima H, Takada Y, Oikawa Y, Takada T, Sakiyama M, Shimizu S, Chiba T, Wakai K, Kawai S, Okada R, Tamura T, Shichijo Y, Akashi A, Sakurai Y, Ichida K, Shinomiya N
    • Organizer
      第25回日本疫学会学術総会
    • Place of Presentation
      ウインクあいち(愛知県・名古屋市)
    • Year and Date
      2015-01-23
  • [Presentation] Clinical and Lifestyle Characteristics associated with HTLV-1 Carrier among General Population2015

    • Author(s)
      Tara Sefanya Kairupan, Rie Ibusuki, Eva Mariane Mantjoro, Hideshi Niimura, Kazuyo Kuwabara, Shin Ogawa, Noriko Nakahata, Yasuhito Nerome, Tetsuhiro Ohwaki, Ken Kusano, Toshiro Takezaki
    • Organizer
      第24回日本疫学会学術総会
    • Place of Presentation
      ウインクあいち(愛知県・名古屋市)
    • Year and Date
      2015-01-23
  • [Presentation] Association of an EPAS1 gene polymorphism with susceptibility to lung adenocarcinoma in female Japanese non-smokers2015

    • Author(s)
      Hidetaka Eguchi, Shinichi Iwamoto, Yumi Nishio, Andica Chandra Putra, Hiroshi Fuchita, Miki Ohe, Akihisa Sutani, Takashige Kuraki, Keiko Hiyama, Isao Murakami, Keiji Tanimoto, Takeshi Isobe
    • Organizer
      第25回日本疫学会学術総会
    • Place of Presentation
      ウインクあいち(愛知県・名古屋市)
    • Year and Date
      2015-01-23
  • [Presentation] SNP-set Kernet Association Test identifirld biological pathways associated with Japanese cedar and hinoki pollen allergy2015

    • Author(s)
      Hattori Y, Hishida A, Moirta E, Nakatochi M, Zhao N, Wu MC, Sasakabe T, Suma S, Okada R, Kawai S, Naito M, Hamajima N, Tanaka H, Wakai K
    • Organizer
      第25回日本疫学会学術総会
    • Place of Presentation
      ウインクあいち(愛知県・名古屋市)
    • Year and Date
      2015-01-23
  • [Presentation] A SNP-set Kernet Association Test detected genetic pathway involved in persistent Helicobacter pyloriinfection2015

    • Author(s)
      Hishida A, Zhao N, Wu MC, Nakatochi M, Naito M, Sasakabe T, Hattori Y, Suma S, Okada R, Kawai S, Morita E, Hamajima N, Tanaka H, Wakai K
    • Organizer
      第25回日本疫学会学術総会
    • Place of Presentation
      ウインクあいち(愛知県・名古屋市)
    • Year and Date
      2015-01-23
  • [Presentation] A20 interacts with Caspase-8 and FADD to protect adult T-cell leukemia cells2015

    • Author(s)
      山岡昇司
    • Organizer
      2nd International Symposium on Protein Modefication in Pathogenic Dysregulation of Signaling
    • Place of Presentation
      東京大学医科学研究所(東京)
    • Year and Date
      2015-01-23
  • [Presentation] Novel screening method for in vivo platelet activation in vascular dementia2015

    • Author(s)
      Kuriyama Nagato, Ozaki etsuko, Matsui Daisuke, Koyama Teruhide, Watanabe Isao, Watanabe Yoshiyuki
    • Organizer
      第25回日本疫学会
    • Place of Presentation
      ウインクあいち(愛知県・名古屋市)
    • Year and Date
      2015-01-21 – 2015-01-23
  • [Presentation] Association between moderate/vigorous intensity of physical activity and urinary levels of 8-hydroxydeoxyguanosine2015

    • Author(s)
      Hara M, Nishida Y, Shimanoe C, Otsuka Y, Nanri H, Higaki Y, Horita M, Kawai K, Li YS, Kasai J, Kasai H, Tanaka K
    • Organizer
      第25回日本疫学会学術総会
    • Place of Presentation
      ウインクあいち(愛知県・名古屋市)
    • Year and Date
      2015-01-21 – 2015-01-23
  • [Presentation] Significant interaction between ADIPOQ gene and higher BMI on HbAlc levels in a Japanese general population2015

    • Author(s)
      Shimanoe C, Higaki Y, Nishida Y, Hara M, Nanri H, Nakamura K, Imaizumi T, Sakamoto T, Taguchi N, Horita M, Shinchi K, Tanaka K, J-MICC Study Group
    • Organizer
      第25回日本疫学会学術総会
    • Place of Presentation
      ウインクあいち(愛知県・名古屋市)
    • Year and Date
      2015-01-21 – 2015-01-23
  • [Presentation] Association between objectively measured physical activity and serum adiponectin in the middle-agedpopulation2015

    • Author(s)
      Nishida Y, Higaki Y, Taguchi N, Hara M, Nakamura K, Nanri H, Imaizumi T, Sakamoto T, Shimanoe C, Horita M, Shinchi K, Tanaka K
    • Organizer
      第25回日本疫学会学術総会
    • Place of Presentation
      ウインクあいち(愛知県・名古屋市)
    • Year and Date
      2015-01-21 – 2015-01-23
  • [Presentation] HTLV-1の病原性発現機構とATLの発症機構2015

    • Author(s)
      渡邉俊樹
    • Organizer
      第5回病原微生物部門セミナー
    • Place of Presentation
      山口大学農学部(山口県・山口市)
    • Year and Date
      2015-01-20
    • Invited
  • [Presentation] アスベスト誘発中皮腫発がんモデルの解析から予防および治療へ2014

    • Author(s)
      豊國伸哉
    • Organizer
      アスベスト関連疾患研究会
    • Place of Presentation
      がん研究会がん研究所吉田富三記念講堂(東京)
    • Year and Date
      2014-12-27
    • Invited
  • [Presentation] 骨転移巣を形成するがん細胞の悪性形質を規定するメカニズム2014

    • Author(s)
      二口充
    • Organizer
      第28回骨代謝セミナー
    • Place of Presentation
      京王プラザホテル(東京)
    • Year and Date
      2014-12-19
    • Invited
  • [Presentation] DNA adductomics in human tissue : a clue toward the origin of human cancer?2014

    • Author(s)
      Haruhiko Sugimura
    • Organizer
      4th Asian Conference on Environmental Mutagens
    • Place of Presentation
      Kolkata, India
    • Year and Date
      2014-12-12
    • Invited
  • [Presentation] Protection of newborns against human T cell leukemia virus type-1 (HTLV-1) infection by maternally-transmitted monoclonal anti-HTLV-1 gp46 antibody2014

    • Author(s)
      Fujii H, Shimizu M, Takahashi Y, Tanaka R, Tanaka Y
    • Organizer
      第43回日本免疫学会総会・学術集会
    • Place of Presentation
      国立京都国際会館(京都府・京都市)
    • Year and Date
      2014-12-11
  • [Presentation] Evaluation of anti-gp46 neutralizing monoclonal antibody vaccine against primary HTLV-1 infection to rats2014

    • Author(s)
      Mukakami Y, Ando S, Tanaka Y, Tanaka R, Matsuda T, Kannagi M, Hasegawa A
    • Organizer
      第43回日本免疫学会総会・学術集会
    • Place of Presentation
      国立京都国際会館(京都府・京都市)
    • Year and Date
      2014-12-11
  • [Presentation] CTL epitope peptide-pulsed dendritic cell vaccine has the potential torestore HTLV-1-specific CTLs to eliminate infected cells2014

    • Author(s)
      Ando S. Hasegawa A, Murakami Y, Takatsuka N, Maeda Y, Masuda T, Kannagi M
    • Organizer
      第43回日本免疫学会学術集会
    • Place of Presentation
      国立京都国際会館(京都府・京都市)
    • Year and Date
      2014-12-10 – 2014-12-12
  • [Presentation] Evaluation of anti-gp46 neutralizing monoclonal antibody vaccine againstprimary HTLV-1 infection to rats2014

    • Author(s)
      Murakami Y, Ando S, Tanaka Y, Tanaka R, Masuda T, Kannagi M, Hasegawa A.
    • Organizer
      第43回日本免疫学会学術集会
    • Place of Presentation
      国立京都国際会館(京都府・京都市)
    • Year and Date
      2014-12-10 – 2014-12-12
  • [Presentation] A link between HTLV-1 leukemogenesis and innate immunity ; involvement of PKR in the constitutive NFκB activation in adult T-cell leukemia cells2014

    • Author(s)
      Kinpara S, Saitoh Y, Hasegawa A, Nakamura M, Yamaoka S, Matsuoka M, Masuda T, Kannagi M.
    • Organizer
      第43回日本免疫学会学術集会
    • Place of Presentation
      国立京都国際会館、京都市
    • Year and Date
      2014-12-10 – 2014-12-12
  • [Presentation] 閉経女性におけるカフェイン摂取と骨密度の検討2014

    • Author(s)
      尾﨑悦子、阪田亜実、弘田真央、瀬古千佳子、加藤里佳、渡邊能行
    • Organizer
      第13回日本栄養改善学会近畿地方会
    • Place of Presentation
      京都女子大学(京都府・京都市)
    • Year and Date
      2014-12-07
  • [Presentation] Landscape of genetic alterations in adult T-cell leukemia/lymphoma2014

    • Author(s)
      Kataoka K, Nagata Y, Kitanaka A, Sato-Otsubo A, Totoki Y, Yasunaga J, Sanada M, Shiraishi Y, Chiba K, Tanaka H, Suzuki H, Sato Y, Shiozawa Y, Yoshizato T, Kon A, Yoshida K, Munakata W, Nakamura H, Hama N, Shide K, Kubuki Y, Hidaka T, Kameda T, Ishiyama K, Miyawaki S, Ishii R, Nureki 0, Nagae G, Aburatani H, Miyano S, Watanabe T, Matsuoka M, Shibata T, Shimoda K, Ogawa S.
    • Organizer
      56th of ASH Annual Meeting and Exposition
    • Place of Presentation
      Moscone Center, San Francisco, U.S.A.
    • Year and Date
      2014-12-07
  • [Presentation] Novel Biological Effects and Distinct Patterns of Rhoa Mutations in Adult T-Cell Leukemia/Lymphoma and Angioimmunoblastic T Cell Lymphoma2014

    • Author(s)
      Nagata Y, Enami T, Kontani K, Kataoka K, Sakata-Yanagimoto M, Kitanaka A, Sato A, Shiraishi Y, Chiba K, Tanaka H, Shiozawa Y, Yoshizato T, Kon A, Yoshida K, Sanada M, Ishiyama K, Miyawaki S, Ishii R, Nureki O, Miyano S, Shimoda K, Watanabe T, Katada T, Chiba S, Ogawa S
    • Organizer
      56th of ASH Annual Meeting and Exposition
    • Place of Presentation
      Moscone Center, San Francisco, U.S.A.
    • Year and Date
      2014-12-07
  • [Presentation] Rapidly changing causal factors of hepatocellular carcinoma(HCC)in Japan2014

    • Author(s)
      Hiroaki Kanda, Noriko Yamamoto, Akio Saiura, Yo Kato, Yuichi Ishikawa, Tomoyuki Kitagawa
    • Organizer
      World cancer congress 2014
    • Place of Presentation
      Melbourne, Australia
    • Year and Date
      2014-12-02 – 2014-12-07
  • [Presentation] HTLV-1感染症に対する免疫療法2014

    • Author(s)
      神奈木真理
    • Organizer
      第4回沖縄ウイルス研究会
    • Place of Presentation
      ANAクラウンプラザホテル(沖縄県・那覇市)
    • Year and Date
      2014-12-02
    • Invited
  • [Presentation] Monitoring clonal composition of HTLV-1-infected cells based on provirus integration sites2014

    • Author(s)
      Sanaz Firouzi, Tadanori Yamochi, Osvany Lopez, Yutaka Suzuki, Kenta Nakai, Sumio Sugano, Toshiki Watanabe
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-27
  • [Presentation] アルツハイマー患者における血漿中マイクロRNAの解析と診断への応用, Analysis of circulating miRNAs in plasma from patients with Alzheimer's disease toward application for the diagnosis2014

    • Author(s)
      二瀬由宇、岡田沙矢香、竹田育子、高橋哲也、松本昌泰、田原栄俊
    • Organizer
      第37回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-11-26
  • [Presentation] 老化を調節するmicroRNAの膵臓がん細胞における機能解析, Analysis of senescence-associated miRNA that suppress pancreatic cancer2014

    • Author(s)
      福永早央里、塩谷文章、嶋本顕、田原栄俊
    • Organizer
      第37回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-26
  • [Presentation] microRNAによる細胞老化誘導機構の解明, Elucidation of mechanism underlying cellular senescence induced by miRNAs2014

    • Author(s)
      山本佑樹、塩谷文章、嶋本顕、田原栄俊
    • Organizer
      第37回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-26
  • [Presentation] Sirtuin 1選択的阻害活性をもつ新規2-hydroxy-1-naphthaldehyde誘導体とその抗がん活性2014

    • Author(s)
      瓦谷泰之、平田佳之、深田尚文、住吉孝明、長岡康夫、伊藤昭博、吉田稔、上里新一
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-26
  • [Presentation] MSM/Ms由来ES細胞を用いたc-MafトランスジェニックMSM/Msマウスラインの作出と解析2014

    • Author(s)
      昇地高雅, 舘山浩紀, 山村研一, 高橋智, 荒木喜美
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-25 – 2014-11-27
  • [Presentation] オートファジー不全と慢性膵炎発症メカニズムの解明2014

    • Author(s)
      大村谷昌樹, 坂田和也, 高城克暢, 松元美由紀, 荒木喜美, 山村研一
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-25 – 2014-11-27
  • [Presentation] CRISPR/Cas9による2本鎖切断・1本鎖切断を利用した場合のマウスES細胞における相同組換え効率の比較2014

    • Author(s)
      荒木喜美, 牟田真由美, 仙波圭, 竹田直樹, 仁木大輔, 松本健, 武田伊世, 山村研一, 大村谷昌樹, 荒木正健
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-25 – 2014-11-27
  • [Presentation] 大脳新皮質の細胞多様性の形成に必須なBrn転写因子の作用形式2014

    • Author(s)
      杉谷善信、杉谷玲子、中井茂康、美野輪治、小川正晴、野田哲生
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-25
  • [Presentation] 成人T細胞白血病におけるEZH2依存的エピジェネティック異常の包括的解析2014

    • Author(s)
      堀真琴、藤川大、中川翔太、田中勇悦、中野和民、渡邉俊樹、山岸誠
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-25
  • [Presentation] 心理ストレスおよび対処行動と血中バイオマーカーの関連 : J-MICC Study-SAGAによる疫学的検討2014

    • Author(s)
      島ノ江千里、原めぐみ、西田裕一郎、田中恵太郎
    • Organizer
      第21回日本行動医学会学術総会(シンポジウム)
    • Place of Presentation
      早稲田大学所沢キャンパス(埼玉県・所沢市)
    • Year and Date
      2014-11-22 – 2014-11-23
  • [Presentation] 臨床診断研究支援活動によるがん研究支援と創薬に向けた展望2014

    • Author(s)
      醍醐弥太郎
    • Organizer
      第59回人類遺伝学会・第21回日本遺伝子診療学会合同大会シンボジウム
    • Place of Presentation
      タワーホール船堀(東京)
    • Year and Date
      2014-11-22
  • [Presentation] アスベストによる中皮腫発がん機構の解明からナノマテリアルのリスク評価ヘシンポジウム1 : 環境発がんのリスク評価における病理学の貢献2014

    • Author(s)
      豊國伸哉
    • Organizer
      第60回日本病理学会秋期特別総会
    • Place of Presentation
      国立劇場おきなわ(沖縄県・浦添市)
    • Year and Date
      2014-11-20 – 2014-11-21
    • Invited
  • [Presentation] 環境発がんのリスク評価における病理学の貢献2014

    • Author(s)
      今井田克己
    • Organizer
      第60回日本病理学会秋期特別集会シンポジウム1
    • Place of Presentation
      国立劇場おきなわ(沖縄県・那覇市)
    • Year and Date
      2014-11-20 – 2014-11-21
    • Invited
  • [Presentation] ヒ素の発がん機序の解明2014

    • Author(s)
      鰐渕英機、魏民
    • Organizer
      第60回日本病理学会秋期特別総会シンポジウム1
    • Place of Presentation
      国立劇場おきなわ(沖縄県・浦添市)
    • Year and Date
      2014-11-20
    • Invited
  • [Presentation] ヒトiPSを活用した肝臓ヒト化マウスの作製と応用2014

    • Author(s)
      山村研一
    • Organizer
      日本人類遺伝学会第59回大会
    • Place of Presentation
      タワーホール船堀(東京)
    • Year and Date
      2014-11-19 – 2014-11-22
    • Invited
  • [Presentation] NPD926, a small molecule inducer of reactive oxygen species, kills cancer cells via glutathione depletion2014

    • Author(s)
      河村達郎、近藤恭光、室井誠、川谷誠、長田裕之
    • Organizer
      26th EORTC-NCI-AACR Symposium on Molecular Targets & Cancer Therapeutics
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2014-11-19
  • [Presentation] Human T-Lymphotropic Virus Type 1 Biomarkers in Patients with Rheumatoid Arthritis2014

    • Author(s)
      Okayama A, Iwanaga M, Sagara Y, Hidaka T, Umekita K, Nakano K, Watanabe T, Yamano Y, Horai Y, Nakamura H, Kawakami A
    • Organizer
      ACR/ARHP Annual Meeting
    • Place of Presentation
      Boston, U.S.A.
    • Year and Date
      2014-11-18
  • [Presentation] Cold transport of mouse epididymides for distributing and archiving genetically engineered mice2014

    • Author(s)
      Takeo, T., Yoshimoto, H., Nakao, S., Ishizuka, Y., Horikoshi, Y., Takeuji, S., Hirose, Y., Mukunoki, A., Fukumoto, K., Kondo, T., Haruguchi, Y., Takeshita, Y., Nakamuta, Y., Tsuchiyama, S., Takahashi, F., Iwamoto, M., Shimizu, N., Li, M., Lloyd, K. and Nakagata, N.
    • Organizer
      第8回次世代を担う若手医療薬科学シンポジウム
    • Place of Presentation
      熊本大学薬学部(熊本県・熊本市)
    • Year and Date
      2014-11-15 – 2014-11-16
  • [Presentation] Application of cold-storage of mouse sperm for shipping genetically engineered mice2014

    • Author(s)
      Takeuji, S., Yoshimoto, H., Nakao, S., Horikoshi, Y., Hirose, Y., Mukunoki, A., Shirakado, K., Takemoto, K., Takeo, T. and Nakagata, N.
    • Organizer
      第8回次世代を担う若手医療薬科学シンポジウム
    • Place of Presentation
      熊本大学薬学部(熊本県・熊本市)
    • Year and Date
      2014-11-15 – 2014-11-16
    • Invited
  • [Presentation] 短時間睡眠における骨量低下リスクおよび自律神経活動2014

    • Author(s)
      栗山長門, 尾崎悦子, 松井大輔, 渡邊能行
    • Organizer
      第54回近畿産業衛生学会
    • Place of Presentation
      近畿大学東大阪キャンパス(大阪府・東大阪市)
    • Year and Date
      2014-11-15
  • [Presentation] ATL発症機構の解析に基づく発症予防・新規治療法の探索2014

    • Author(s)
      渡邉俊樹
    • Organizer
      第13回さいたま血液勉強会、大日本住友製薬(株)主催
    • Place of Presentation
      大日本住友製薬(株)埼玉支店(埼玉県・さいたま市)
    • Year and Date
      2014-11-14
    • Invited
  • [Presentation] Association between Fusobacterium expression and molecular feature using 391 Japanese patients with colorectal cancer2014

    • Author(s)
      能正勝彦
    • Organizer
      The 8th International Conference of the International Society of Gastroenterological Carcinogenesis
    • Place of Presentation
      ホテル日航福岡(福岡県・福岡市)
    • Year and Date
      2014-11-14
  • [Presentation] Characterization of Serine/Threonine phosphatase LAPP1 as a diagnostic and therapeutic target for lung cancer2014

    • Author(s)
      Daigo Y, Nakamura Y
    • Organizer
      The 11th International Conference on Protein Phosphatase
    • Place of Presentation
      東北大学医学部艮陵会館(宮城県・仙台市)
    • Year and Date
      2014-11-13
  • [Presentation] 大腸癌におけるmicroRNA-31とBRAF遺伝子変異や予後との関連2014

    • Author(s)
      五十嵐央祥
    • Organizer
      第25回消化器癌発生学会総会
    • Place of Presentation
      ホテル日航福岡(福岡県・福岡市)
    • Year and Date
      2014-11-13
  • [Presentation] HSP90阻害薬投与により変動するATL遺伝子群の探索2014

    • Author(s)
      池辺詠美, 緒方正男, 塚本善之, 手塚健太, Nichole Fife, 松本昂, 末岡栄三郎, 堀光雄, 長谷川寛雄, 森下和広, 田中勇悦, 藤澤順一, 守山正胤, 西園晃, 伊波英克
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-11
  • [Presentation] HTLV-1gp46、OX40およびCD25を標的としたモノクローナル抗体によるHTLV-1感染細胞の制御2014

    • Author(s)
      高橋良明, 清水衡, 呂城拓也, 田中礼子, 國廣真里枝, 藤猪英樹, 田中勇悦
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-11
  • [Presentation] HTLV-1 Tax抗原はT細胞表面にCD83を誘導する : Tax陽性細胞のlive cell sorting2014

    • Author(s)
      藤猪英樹, 高橋良明, 田中礼子, 福島卓也, 友寄毅昭, 水口真理子, 中村正孝, 田中勇悦
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-11
  • [Presentation] HTLV-1Env発現ウイルス産生細胞におけるHTLV-1受容体GLUT1の制御機構の解析2014

    • Author(s)
      前田洋助, 寺沢広美, 光浦智将, 中島詩織, 門出和精, 田中勇悦, 遊佐敬介, 原田信志
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-11
  • [Presentation] Heat-ShockによるHTLV-1 Taxおよびgp46タンパクの発現増強と感染促進2014

    • Author(s)
      國廣真里枝, 藤猪英樹, 西連寺剛, 高橋良明, 田中礼子, 田中勇悦
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-11
  • [Presentation] HTLV-1 PVLとHLA Class Ⅰ結合peptideの乖離時間との関連2014

    • Author(s)
      相良康子、井上由紀子、守田麻衣子、後藤信代、岩永正子、矢持忠徳、渡邉俊樹、浜口功、相良康弘、清川博之
    • Organizer
      第62回日本ウイルス学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-11
  • [Presentation] The roles of acquired and innate immunity in HTLV1-infgection : Implacation for therapy and pathogenesis2014

    • Author(s)
      Mari Kannagi, Atsuhiko Hasegawa, Shuichi Kinpara, Youko Suehiro.
    • Organizer
      第62回日本ウイルス学会学術集会シンポジウム
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-10 – 2014-11-12
  • [Presentation] HTLV-1 bZIP factorが惹起する炎症におけるIFNγの役割2014

    • Author(s)
      三田上侑生、安永純一朗、大島孝一、松岡雅雄
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-10 – 2014-11-12
  • [Presentation] Anti-CCR4抗体はTregと感染細胞を同時に標的にする事で、STLV-1自然感染ニホンザルでのウイルス特異的免疫反応を活性化させる2014

    • Author(s)
      菅田謙治、安永純一朗、三浦未知、明里宏文、小柳義夫、小原道法、松岡雅雄
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-10 – 2014-11-12
  • [Presentation] 集団栄養調査における食事記録から算出した栄養摂取量の3日分と1日分の妥当性研究2014

    • Author(s)
      尾﨑悦子、弘田真央、瀬古千佳子、阪田亜実、加藤里佳、鍋島加名栄、宮谷史太郎、松井大輔、渡邉功、栗山長門、渡邊能行
    • Organizer
      第73回日本公衆衛生学会
    • Place of Presentation
      宇都宮東武グランドホテル(栃木県・宇都宮市)
    • Year and Date
      2014-11-07
  • [Presentation] 唾液ストレスマーカーと口腔内状態との関連に関する検討2014

    • Author(s)
      松井大輔、渡邉功、宮谷史太郎、尾﨑悦子、弘田真央、瀬古千佳子、阪田亜実、栗山長門、渡邊能行
    • Organizer
      第73回日本公衆衛生学会
    • Place of Presentation
      宇都宮東武グランドホテル(栃木県・宇都宮市)
    • Year and Date
      2014-11-06
  • [Presentation] Molecular mechanisms of leukemogenesis of adult T-cell leukemia (ATL) caused by HTLV-12014

    • Author(s)
      Watanabe T.
    • Organizer
      2d IARI Symposium
    • Place of Presentation
      Lyon, France
    • Year and Date
      2014-11-03
  • [Presentation] CD30 expressing cells in HTLV-1 carriers reveal abnormal nuclear morphology resembling flower cells2014

    • Author(s)
      Nakashima M, Yamochi T, Higashihara M, Watanabe T, Horie R
    • Organizer
      第76回日本血液学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪府・大阪市)
    • Year and Date
      2014-11-01
  • [Presentation] 全国医療機関における成人T細胞白血病・リンパ腫(ATL)患者の実態調査 2010年~2011年2014

    • Author(s)
      野坂生郷、岩永正子、石澤賢一、石田陽治、内丸薫、石塚賢治、天野正宏、石田高司、今泉芳孝、鵜池直邦、宇都宮與、大島孝一、河井一浩、田中淳司、戸倉新樹、飛内賢正、渡邉俊樹、塚崎邦弘
    • Organizer
      第76回日本血液学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪府・大阪市)
    • Year and Date
      2014-11-01
  • [Presentation] Tumor-specific gene expression leads to p38 and Hedgehog signaling activation in adult T cell leukemia2014

    • Author(s)
      Yamagishi M, Takahashi R, Sakai N, Fujikawa D, Nakagawa S, Yamochi T, Yamochi T, Nakano K, Uchimaru K, Utsunomiya A, Watanabe T
    • Organizer
      第76回日本血液学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪府・大阪市)
    • Year and Date
      2014-11-01
  • [Presentation] Distinct patterns of RHOA mutations in Adult T-Cell Leukemia/Lymphoma and peripheral T-Cell lymphomas2014

    • Author(s)
      Nagata Y, Enami T, Sakata-Yanagimoto M, Kataoka K, Kitanaka A, Sato A, Shiraishi Y, Chiba K, Tanaka H, Shiozawa Y, Yoshizato T, Kon A, Yoshida K, Sanada M, Ishiyama K, Miyawaki S, Ishii R, Nureki O, Miyano S, Shimoda K, Watanabe T, Chiba S, Ogawa S
    • Organizer
      第76回日本血液学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪府・大阪市)
    • Year and Date
      2014-11-01
  • [Presentation] Landscape of genetic alterations in adult T-cell leukemia/lymphoma2014

    • Author(s)
      Kataoka K, Nagata Y, Kitanaka A, Sato-Otsubo A, Totoki Y, Yasunaga J, Sanada M, Shiraishi Y, Chiba K, Tanaka H, Suzuki H, Sato Y, Shiozawa Y, Yoshizato T, Kon A, Yoshida K, Munakata W, Nakamura H, Hama N, Shide K, Kubuki Y, Hidaka T, Kameda T, Ishiyama K, Miyawaki S, Ishii R, Nureki 0, Nagae G, Aburatani H, Miyano S, Watanabe T, Matsuoka M, Shibata T, Shimoda K, Ogawa S
    • Organizer
      第76回日本血液学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪府・大阪市)
    • Year and Date
      2014-11-01
  • [Presentation] Dissecting cancer biology by studying induced pluripotency2014

    • Author(s)
      Yamada Y.
    • Organizer
      Nature Conference, Nuclear Reprogramming and the Cancer Genome2014
    • Place of Presentation
      Guangzhou, China
    • Year and Date
      2014-10-31 – 2014-11-02
    • Invited
  • [Presentation] 睡眠者における安静および起立負荷時の心拍変動と骨量減少の関連2014

    • Author(s)
      栗山長門、鍋島加名栄、岩佐弘一
    • Organizer
      第67回日本自律神経学会総会
    • Place of Presentation
      ラフレ埼玉(埼玉県・さいたま市)
    • Year and Date
      2014-10-31
  • [Presentation] Suppressive effect of the farnesyltransferase inhibitor for aberrant crypt foci as a precursor of colorectal cancer2014

    • Author(s)
      Kimura T, Muguruma N, Takayama T.
    • Organizer
      第56回日本消化器病学会大会(JDDW2014)
    • Place of Presentation
      神戸国際会議場(兵庫県・神戸市)
    • Year and Date
      2014-10-25
  • [Presentation] 60代女性における橈骨皮質骨および橈骨海綿骨骨密度の脆弱要因の検討2014

    • Author(s)
      尾﨑悦子、栗山長門、松井大輔、渡邉功、稲葉雅章、三島誉史、水野成人、弘田真央、米田勇太郎、渡邊能行
    • Organizer
      第16回日本骨粗鬆症学会
    • Place of Presentation
      京王プラザホテル(東京)
    • Year and Date
      2014-10-24
  • [Presentation] 短時間睡眠者における骨量低下リスクおよび自律神経活動に関する横断的検討2014

    • Author(s)
      栗山長門、尾﨑悦子、稲葉雅章、堀井基行、水野成人、黒川正夫、岩佐弘一、松井大輔、米田勇太郎、渡邊能行
    • Organizer
      第16回日本骨粗鬆症学会
    • Place of Presentation
      京王プラザホテル(東京)
    • Year and Date
      2014-10-23
  • [Presentation] Cryopreservation of mouse sperm2014

    • Author(s)
      Nakagata, N.
    • Organizer
      AMMRA-AMPC STUDENT WORKSHOP
    • Place of Presentation
      Canberra, Australia
    • Year and Date
      2014-10-22 – 2014-10-23
    • Invited
  • [Presentation] Do you know how to maintain genetic quality of outbred colonies?2014

    • Author(s)
      Katoh H
    • Organizer
      65th AALAS National Meeting
    • Place of Presentation
      San Antonio Convention Center, TX, U.S.A.
    • Year and Date
      2014-10-19 – 2014-10-23
    • Invited
  • [Presentation] セリン・スレオニンフォスファターゼLAPP1の肺発がんにおける機能解析と診断・治療への応用2014

    • Author(s)
      醍醐弥太郎、中村祐輔
    • Organizer
      第87回日本生化学会大会シンポジウム
    • Place of Presentation
      国立京都国際会館・グランドプリンスホテル京都(京都府・京都市)
    • Year and Date
      2014-10-18
  • [Presentation] Longitudinal relationships of perceived stress and coping strategies with C-reactive protein in middle-aged and older men and women2014

    • Author(s)
      Shimanoe C, Hara M, Nishida Y, Nanri H, Otsuka Y, Horita M, Yasukata J, Miyoshi N, Yamada Y, Higaki Y, Shinchi K, Tanaka K
    • Organizer
      WPA Section on Epidemiology and Public Health Meeting
    • Place of Presentation
      奈良県新公会堂(奈良県・奈良市)
    • Year and Date
      2014-10-16 – 2014-10-18
  • [Presentation] 酸素と鉄の親和性 : 鉄過剰と発がん2014

    • Author(s)
      豊國伸哉
    • Organizer
      レドックスシンポジウム : 酸素生物学の誕生
    • Place of Presentation
      名古屋大学ES総合館ESホール(愛知県・名古屋市)
    • Year and Date
      2014-10-11
    • Invited
  • [Presentation] ATL発症機構の解析に基づく発症予防法と治療法の開発2014

    • Author(s)
      渡邉俊樹
    • Organizer
      ATL学術集会、協和発酵キリン(株)主催
    • Place of Presentation
      盛岡グランドホテル(岩手県・盛岡市)
    • Year and Date
      2014-10-09
    • Invited
  • [Presentation] Line up new enzyme-linked immune-sorbent assay (ELISA) kits for quantitation of HTLV-1(gp46, p24, Tax), Tax-related antigens (OX40, OX40L, CD25) and HIV-1 p242014

    • Author(s)
      Tanaka R, Kodama A, Tanaka Y.
    • Organizer
      4th World Congress on Virology
    • Place of Presentation
      San Antonio, U.S.A.
    • Year and Date
      2014-10-07
  • [Presentation] Control of infection with human T cell leukemia virus type-1 (HTLV-1) by humanized neutralizing anti-HTLV-1 gp46 antibody2014

    • Author(s)
      Tanaka Y
    • Organizer
      4th World Congress on Virology
    • Place of Presentation
      San Antonio, U.S.A.
    • Year and Date
      2014-10-07
  • [Presentation] Isolation and target identification of pyrrolizilactone2014

    • Author(s)
      長田裕之
    • Organizer
      2014 Osong International Symposium
    • Place of Presentation
      Osong, Korea
    • Year and Date
      2014-10-07
  • [Presentation] Platinum TALENによる効率的な遺伝子改変マウスの作製2014

    • Author(s)
      中川佳子、佐久間哲史、中潟直己、大村谷昌樹、山本卓
    • Organizer
      第4回ゲノム編集研究会
    • Place of Presentation
      広島国際会議場(広島県・広島市)
    • Year and Date
      2014-10-06
  • [Presentation] 老化誘導型核酸医薬の開発2014

    • Author(s)
      田原栄俊
    • Organizer
      新適塾「未来創薬への誘い」第28回会合
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府・豊中市)
    • Year and Date
      2014-10-06
    • Invited
  • [Presentation] HTLV-I感染細胞および上皮系腫瘍細胞においてユビキチン化修飾酵素A20はcaspase-8抑制因子として機能する2014

    • Author(s)
      斉藤愛記、持田佳奈子、鶴山惠理、市川裕菜、大友悠太郎、掛谷綾香、深澤麻純、宇野雅哉、徳永文稔、宇都宮與、渡邉俊樹、山岡昇司
    • Organizer
      新学術領域研究「修飾シグナル病」若手ワークショップ
    • Place of Presentation
      ホテルあかね(神奈川県・足柄下郡湯河原町)
    • Year and Date
      2014-09-30 – 2014-10-02
  • [Presentation] テロメア検査、マイクロRNA検査を用いた健康管理への活用2014

    • Author(s)
      田原栄俊
    • Organizer
      第24回日本医療薬学会年会シンポジウム
    • Place of Presentation
      名古屋国際会議場(愛知県・名古屋市)
    • Year and Date
      2014-09-28
    • Invited
  • [Presentation] Exploration of sensitivity/resistance-related genes for docetaxel, cisplatin and 5-fluorouracil used for the TPF treatment of hypopharyngeal cancer2014

    • Author(s)
      Yumiko Shimamura, Hidetaka Eguchi, Satoru Wada, Mitsuhiko Nakahira, Yasushi Okazaki, Testuya Yoda, Reidar Grenman, Masashi Sugasawa, Masahiko Nishimyama
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-27
  • [Presentation] EGFR expression and efficacy of anti-EGFR antibody in colorectal cancer2014

    • Author(s)
      Okada Y, Tanaka H, Taniguchi T, Takayama T
    • Organizer
      The 73rd annual meeting of the Japanese Cancer Association
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2014-09-27
  • [Presentation] MicroRNA-31-5p expression in relation to BRAF mutation, CIMP status and colorectal continuum in serrated pathway2014

    • Author(s)
      能正勝彦
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-27
  • [Presentation] Cancer initiating cekk of lung squamous cell carcinoma in mice might be cerived from the bronchiolar alveolar stem cell2014

    • Author(s)
      Yamano S, Wei M, Fujioka M, Wanibuchi H
    • Organizer
      39th EAMO Congress
    • Place of Presentation
      Madrid, Spain
    • Year and Date
      2014-09-26 – 2014-09-30
  • [Presentation] Des-g-carboxy prothrombin is produced by elevated transcription of prothrombin gene in hepatocellular carcinoma2014

    • Author(s)
      Taniguchi T, Kagemoto K, Tanaka H, Tanaka T, Tomonari T, Sannomiya K, Miyamoto H, Muguruma N, Takayama T.
    • Organizer
      The 73rd annual meeting of the Japanese Cancer Association
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2014-09-26
  • [Presentation] CE-TOFMS法を用いたATL細胞の小分子量メタボライトのプロファイリング2014

    • Author(s)
      伊波英克, 池辺詠美, 紙健次郎, 長谷川寛雄, 田中勇悦, 森下和広, 堀光雄
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-26
  • [Presentation] HTLV-I感染中和及びADCC活性を持つヒト化ラット由来単クロン抗体2014

    • Author(s)
      田中勇悦
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-26
  • [Presentation] 成人T細胞白血病/リンパ腫と他の末梢性T細胞性腫瘍におけるRHOAの特徴的な変異分布と生物学的機能の解析2014

    • Author(s)
      永田安伸、榎並輝和、坂田(柳元)麻実子、片岡圭亮、北中明、佐藤亜以子、白石友一、眞田昌、宮野悟、下田和哉、渡邉俊樹、千葉滋、小川誠司
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-26
  • [Presentation] 神奈川県立がんセンターにおけるがん関連試料の収集と提供2014

    • Author(s)
      宮城洋平, 今井浩三
    • Organizer
      第73回日本癌学会学術総会シンポジウム
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-26
  • [Presentation] SPINK1ノックインマウスではオートファジー機能不全により慢性膵炎が惹起される2014

    • Author(s)
      坂田和也, 大村谷昌樹, 荒木喜美, 高城克暢, 橋本大輔, 近本亮, 山村研一, 馬場秀夫
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
  • [Presentation] CHOP欠損による慢性炎症からの膵線維化進展2014

    • Author(s)
      高城克暢, 大村谷昌樹, 橋本大輔, 東孝暁, 坂本慶太, 坂田和也, 新田英利, 林洋光, 近本亮, 別府透, 荒木喜美, 山村研一, 馬場秀夫
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
  • [Presentation] TACC3を標的とした低分子化合物の開発と応用2014

    • Author(s)
      八尾良司、長田裕之、吉田稔、野田哲生
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
  • [Presentation] オルガノイドを用いたTACC3阻害による消化管腫瘍抑制機構の解析2014

    • Author(s)
      小柳潤、八尾良司、野田哲生
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
  • [Presentation] 哺乳動物細胞の低用量ストレス応答におけるヒストンシャペロンHIRAの機能解析2014

    • Author(s)
      長垣良和、中條萌絵子、樽本雄介、八尾良司、石川冬木
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
  • [Presentation] 消化管腫瘍形成におけるAPC1309の機能解析2014

    • Author(s)
      高野洋、八尾良司、野田哲生
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
  • [Presentation] 小脳髄芽腫の散発性マウスモデルを用いた腫瘍微小環境の解析2014

    • Author(s)
      柳沼克幸
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
  • [Presentation] Molecular basis underlying the multi-step process in spontaneous medulloblastoma development2014

    • Author(s)
      Sugitani Y., Yaginuma K., Noda T.
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
  • [Presentation] シンポジウム : ゲノム制御から見た環境発がん : 中皮腫発癌機構解明とその予防への挑戦2014

    • Author(s)
      豊國伸哉
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Invited
  • [Presentation] ハムスター化学発がんモデルを用いた1,2-dichloropropaneの発がん修飾作用の検討2014

    • Author(s)
      魏民、下村衣里、藤岡正喜、山野荘太郎、梯アンナ、石井真美、武下正憲、房赫、鰐渕英機
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
  • [Presentation] ヒトNASH肝細胞癌におけるプロテオーム解析を用いた分枝メカニズムの検討2014

    • Author(s)
      石井真美、梯アンナ、桑江優子、大澤政彦、魏民、鰐渕英機
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
  • [Presentation] gpt deltaラットを用いた2-AAFの肝発がん性および変異原性の包括的評価モデルの検討2014

    • Author(s)
      藤岡正喜、魏民、山野荘太郎、梯アンナ、石井真美、下村衣里、三島胡桃、房赫、鰐渕英機
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
  • [Presentation] ヒト肝細胞癌における新治療ターゲットの検索 : CNPY2及びCACHD12014

    • Author(s)
      梯アンナ、石井真美、桑江優子、房赫、藤岡正喜、魏民、鰐渕英機
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
  • [Presentation] ピロリ菌CagA発現マウス胃粘膜における粘液細胞化生(SPEM)の誘導2014

    • Author(s)
      柳谷公平、藤井裕美子、神田浩明、畠山昌則
    • Organizer
      第73回日本癌学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
  • [Presentation] ビスフォスフォネートあるいは抗RANKL抗体で治療した骨巨細胞腫の組織学的検討2014

    • Author(s)
      神田浩明、元井紀子、杉浦善弥、谷沢泰介、松本誠一、町並陸生、石川雄一
    • Organizer
      第73回日本癌学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
  • [Presentation] FNCLCCシステムを用いた、組織型組織亜型レベルでの軟部肉腫の予後解析2014

    • Author(s)
      杉浦善弥、元井紀子、神田浩明、岡田絵里奈、牛嶋大、松浦正明、松本誠一、中山淳、町並陸生、石川雄一
    • Organizer
      第73回日本癌学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
  • [Presentation] Immune control of the retrovirus-induced adult T-cell leukemia : fighting with invisible enemy2014

    • Author(s)
      Kannagi M.
    • Organizer
      第73回日本癌学会総会シンポジウム
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
  • [Presentation] Involvement of PKR and anti-sense HTLV-1 transcripts in the constitutive activation of NF κ B in ATL cells2014

    • Author(s)
      Shuichi Kinpara, Yasunori Saitoh, Atsuhiko Hasegawa, Atae Utsunomiya, Masato Masuda, Yasushi Miyazaki, Masao Matsuoka, Masataka Nakamura, Shoji Yamaoka, Takao Masuda, Mari Kannagi.
    • Organizer
      第73回日本癌学会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
  • [Presentation] HTLV-1による発がん機構2014

    • Author(s)
      松岡雅雄
    • Organizer
      第73回日本癌学会学術総会 シンホジウム
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
  • [Presentation] HTLV-1 bZIP factor(HBZ)はRbタンパクと相互作用し、E2F-1/Rb経路を改変する2014

    • Author(s)
      川月章弘、安永純一朗、松岡雅雄
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
  • [Presentation] 転写因子TCF1、LEF1はHTLV-1 Taxを阻害し末梢Tリンパ球への感染指向性に関与する2014

    • Author(s)
      安永純一朗、松岡雅雄
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
  • [Presentation] Elucidation of transcriptional regulatory circuitry involved in the molecular pathogenesis of lung cancer2014

    • Author(s)
      Takahashi T
    • Organizer
      第73回日本癌学会学術総会シンポジウム
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
  • [Presentation] A pivotal role of CERS6 on the sphingolipid metabolic pathways and tumor metastasis in lung cancer2014

    • Author(s)
      Suzuki M, Murate T, Kyogashima M, Takahashi T
    • Organizer
      第73回日本癌学会学術総会シンポジウム
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
  • [Presentation] ラットモデルにおけるHTLV-1新規感染に対する抗HTLV-1gp46中和抗体ワクチンの効果2014

    • Author(s)
      村上悠二, 安藤聡美, 田中勇悦, 田中礼子, 増田貴夫, 神奈木真理, 長谷川温彦
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25
  • [Presentation] ATL細胞におけるEZH2依存的エビジェネティック異常の包括的解析2014

    • Author(s)
      藤川大, 山岸誠, 中川翔太, 黒川直也, 副島あい, 石田尚臣, 田中勇悦, 中野和民, 渡邉俊樹
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25
  • [Presentation] 「ATL発症の基盤となるゲノム・エピゲノム異常の解析」、シンポジウム : 16. ATL発がん機構と治療の新展開2014

    • Author(s)
      渡邉俊樹、山岸誠
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25
    • Invited
  • [Presentation] 「成人T細胞白血病/リンパ腫におけるゲノム異常の網羅的解析」、シンポジウム : 16. ATL発がん機構と治療の新展開2014

    • Author(s)
      片岡圭亮、永田安伸、北中明、佐藤亜以子、十時康、安永純一朗、油谷浩幸、宮野悟、渡邉俊樹、松岡雅雄、柴田龍弘、下田和哉、小川誠司
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25
  • [Presentation] ATL細胞におけるEZH2依存的エピジェネティック異常の包括的解析2014

    • Author(s)
      藤川大、山岸誠、中川翔太、黒川直也、副島あい、石田尚臣、田中勇悦、中野和民、渡邉俊樹
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25
  • [Presentation] Putative ATL tumor initiating cellsの解析2014

    • Author(s)
      矢持忠徳、守田陽平、矢持淑子、Sanaz Firouzi、佐々木陽介、渡辺信和、内丸薫、宇都宮與、渡邉俊樹
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25
  • [Presentation] A new high-throughput method to investigate the clonality of HTLV-1-infected cells based on provirus integration sites2014

    • Author(s)
      Sanaz Firouzi, Tadanori Yamochi, Yosvany Lopez, Yutaka Suzuki, Kenta Nakai, Sumio Sugano, Toshiki Watanabe
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25
  • [Presentation] DNAメチル化解析による肝芽腫の新規予後予測マーカーの確立2014

    • Author(s)
      本多昌平
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25
  • [Presentation] 生活習慣病の遺伝子環境交互作用の解明を目指して : 日本多施設共同コーホート研究-佐賀地区-2014

    • Author(s)
      田中恵太郎
    • Organizer
      第17回日本運動疫学会学術総会
    • Place of Presentation
      長崎大学文教キャンパス(長崎県・長崎市)
    • Year and Date
      2014-09-18
  • [Presentation] Optical Molecular Imaging and Assessment of Therapeutic Response of Colorectal Cancer Targeting Epidermal Growth Factor Receptor2014

    • Author(s)
      Muguruma N, Miyamoto Y, Fujimoto S, Fujino Y, Okada Y, Kitamura S, Kimura T, Okamoto K, Miyamoto H, Takayama T.
    • Organizer
      The world Molecular Imaging Congress
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2014-09-17 – 2014-09-20
  • [Presentation] シンポジウム1「鉄と腫瘍」過剰鉄による発がん機構の解明からその予防へ2014

    • Author(s)
      豊國伸哉、蒋麗、岡崎泰昌、赤塚慎也
    • Organizer
      第38回日本鉄バイオサイエンス学会学術集会
    • Place of Presentation
      仙台国際センター(宮城県・仙台市)
    • Year and Date
      2014-09-06 – 2014-09-07
    • Invited
  • [Presentation] 成人T細胞白血病ウイルス(HTLV-I)の感染予防ワクチン : ヒト化感染中和抗体2014

    • Author(s)
      田中勇悦, 清水衡, 高橋良明, 藤猪英樹, 田中礼子
    • Organizer
      第51回日本ウイルス学会九州支部総会
    • Place of Presentation
      城山観光ホテル(鹿児島県・鹿児島市)
    • Year and Date
      2014-09-06
  • [Presentation] CTLエピトープペプチドパルス樹状細胞によるウイルス特異的T細胞の誘導および感染細胞の制御2014

    • Author(s)
      安藤聡美、長谷川温彦、村上悠二、神奈木真理
    • Organizer
      血液疾患免疫療法学会
    • Place of Presentation
      京都大学芝蘭会館(京都府・京都市)
    • Year and Date
      2014-09-05 – 2014-09-06
  • [Presentation] HTLV-1 Tax抗原はT細胞表面にCD83を誘導する : Tax陽性細胞のlive cell sorting2014

    • Author(s)
      藤猪英樹, 高橋良明, 田中礼子, 福島卓也, 友寄毅昭, 水口真理子, 中村正孝, 田中勇悦
    • Organizer
      第51回日本ウイルス学会九州支部総会
    • Place of Presentation
      城山観光ホテル(鹿児島県・鹿児島市)
    • Year and Date
      2014-09-05
  • [Presentation] レクチンアレイによるATLバイオマーカーの探索2014

    • Author(s)
      池辺詠美, 緒方正男, 手塚健太, ファイフ ニコール, 松本昂, 末岡栄三郎, 堀光雄, 長谷川寛雄, 森下和広, 田中勇悦, 児玉大介, 出雲周二, 藤澤順一, 西園晃, 伊波英克
    • Organizer
      第51回日本ウイルス学会九州支部総会
    • Place of Presentation
      城山観光ホテル(鹿児島県・鹿児島市)
    • Year and Date
      2014-09-05
  • [Presentation] 腎発がんモデルを用いた発がん機構の解明及び転移モデルへの応用2014

    • Author(s)
      山野荘太郎、三島胡桃、藤岡正喜、魏民、鰐渕英機
    • Organizer
      平成26年度がん若手研究者ワークショップ
    • Place of Presentation
      蓼科グランドホテル滝の湯(長野県・茅野市)
    • Year and Date
      2014-09-03 – 2014-09-06
  • [Presentation] 細胞老化を誘導するmicroRNAの網羅的スクリーニング, High-content screening of senescence-associated microRNAs2014

    • Author(s)
      山本佑樹、塩谷文章、嶋本顕、田原栄俊
    • Organizer
      平成26年度がん若手研究者ワークショップ
    • Place of Presentation
      蓼科グランドホテル滝の湯(長野県・茅野市)
    • Year and Date
      2014-09-03 – 2014-09-06
  • [Presentation] ハムスターBOP二段階胆膵管発がんモデルを用いた1,2-dichloropropaneの発がん修飾作用の検討2014

    • Author(s)
      下村衣里、魏民、藤岡正喜、山野荘太郎、梯アンナ、三島胡桃、鰐渕英機
    • Organizer
      第29回発癌病理研究会
    • Place of Presentation
      スパリゾートハワイアンズコンベンションセンター(福島県・いわき市)
    • Year and Date
      2014-09-01 – 2014-09-03
  • [Presentation] EHEN誘発ラット腎発がんにおける発がん機序の解明PI3K/Akt/mTOR signaling pathway及びNADPH oxidaseの役割2014

    • Author(s)
      三島胡桃、山野荘太郎、藤岡正喜、魏民、下村衣里、鰐渕英機
    • Organizer
      第29回発癌病理研究会
    • Place of Presentation
      スパリゾートハワイアンズコンベンションセンター(福島県・いわき市)
    • Year and Date
      2014-09-01 – 2014-09-03
  • [Presentation] Connective tissue growth factor and beta-catenin consitute an autocrinne loop for activation in rat sarcomatoid mesothelioma2014

    • Author(s)
      Jiang L and Toyouni S
    • Organizer
      第6回日本CCNファミリー研究会 シンポジウム : CCNファミリー研究のフロンティア
    • Place of Presentation
      岡山大学(岡山県・岡山市)
    • Year and Date
      2014-08-30
    • Invited
  • [Presentation] 細胞老化における細胞外小胞エクソソーム分泌の生物学的意義の探索, The analysis of biological significance of exosomes in replicative senescence2014

    • Author(s)
      岡田恵、宗岡美紗、岡本沙矢香、二瀬由宇、塩谷文章、嶋本顕、田原栄俊
    • Organizer
      第6回日本RNAi研究会
    • Place of Presentation
      グランドプリンスホテル広島(広島県・広島市)
    • Year and Date
      2014-08-29
  • [Presentation] Direct detection of extracellular vesicles and exRNA, Direct detection of extracellular vesicles and exRNA2014

    • Author(s)
      田原栄俊
    • Organizer
      第1回日本細胞外小胞学会
    • Place of Presentation
      グランドプリンスホテル広島(広島県・広島市)
    • Year and Date
      2014-08-28
    • Invited
  • [Presentation] 老化を調節するmicroRNAによる膵臓がん抑制機構の解析, Functional analysis of senescence-associated miRNA suppresses pancreatic cancer2014

    • Author(s)
      福永早央里、塩谷文、嶋本顕、田原栄俊
    • Organizer
      第6回日本RNAi研究会
    • Place of Presentation
      グランドプリンスホテル広島(広島県・広島市)
    • Year and Date
      2014-08-28
  • [Presentation] 細胞老化を誘導するmicroRNAの網羅的スクリーニング, High-content screening of senescence-associated microRNAs2014

    • Author(s)
      山本佑樹、塩谷文章、嶋本顕、田原栄俊
    • Organizer
      第6回日本RNAi研究会
    • Place of Presentation
      グランドプリンスホテル広島(広島県・広島市)
    • Year and Date
      2014-08-28
  • [Presentation] スペクトル型フローサイトメーターSP6800によるエクソソームの一粒子測定, Direct Detection of Exosome by SP6800 Spectral Analyzer2014

    • Author(s)
      品末聡也、岡田恵、宗岡美紗、植田俊樹、佐古直紀、新田尚、田原栄俊
    • Organizer
      第6回日本RNAi研究会
    • Place of Presentation
      グランドプリンスホテル広島(広島県・広島市)
    • Year and Date
      2014-08-28
  • [Presentation] アルツハイマー患者における血漿中マイクロRNAの解析と診断への応用, Analysis of plasma miRNAs in patients with Alzheimer's disease as applied to the diagnosis2014

    • Author(s)
      二瀬由宇、岡田沙矢香、竹田育子、高橋哲也、松本昌泰、田原栄俊
    • Organizer
      第6回日本RNAi研究会
    • Place of Presentation
      グランドプリンスホテル広島(広島県・広島市)
    • Year and Date
      2014-08-28
  • [Presentation] 抗HTLV-1gp46中和ADCC抗体によるin vivo HTLV-1感染制御2014

    • Author(s)
      藤猪英樹, 清水衡, 高橋良明, 田中礼子, 田中勇悦
    • Organizer
      第1回日本HTLV-1学会学術集会
    • Place of Presentation
      東京大学医科学研究所1号館講堂(東京)
    • Year and Date
      2014-08-24
  • [Presentation] ATL細胞におけるEZH2依存的エピジェネティック異常の包括的解析2014

    • Author(s)
      藤川大, 山岸誠, 黒川直也, 副島あい, 中川翔太, 石田尚臣, 田中勇悦, 中野和民, 渡邉俊樹
    • Organizer
      第1回日本HTLV-1学会学術集会
    • Place of Presentation
      東京大学医科学研究所1号館講堂(東京)
    • Year and Date
      2014-08-24
  • [Presentation] HTLV-1によるTh1-like CD4+CCR4+T細胞の発生機構の解析2014

    • Author(s)
      新谷奈津美, 佐藤知雄, 安藤仁, 外丸詩野, Ariella Coler-Reilly, 八木下尚子, 山内淳司, 長谷川温彦, 神奈木真理, 田中勇悦, 宇都宮與, 山野嘉久
    • Organizer
      第1回日本HTLV-1学会学術集会
    • Place of Presentation
      東京大学医科学研究所1号館講堂(東京)
    • Year and Date
      2014-08-24
  • [Presentation] ATL細胞内NF-κB経路活性化に対するPKR分子とHTLV-I LTR領域由来転写産物の寄与2014

    • Author(s)
      金原秀一、斉藤愛記、長谷川温彦、宇都宮與、増田昌人、宮崎泰司、松岡雅雄、中村正孝、山岡昇司、増田貴夫、神奈木真理
    • Organizer
      2014HTLV-1学会
    • Place of Presentation
      東京大学医科学研究所(東京)
    • Year and Date
      2014-08-23 – 2014-08-24
  • [Presentation] HTLV-1感染細胞における自然免疫応答の検討2014

    • Author(s)
      伊藤さやか、金原秀一、金井秀美、野上開、Sawada Leila, 永野佳子、長谷川温彦、神奈木真理
    • Organizer
      2014HTLV-1学会
    • Place of Presentation
      東京大学医科学研究所(東京)
    • Year and Date
      2014-08-23 – 2014-08-24
  • [Presentation] HTLV-1感染細胞におけるA20はユビキチン化修飾酵素活性非依存的に細胞生存を支える2014

    • Author(s)
      齋藤愛記、持田佳奈子、鶴山惠理、徳永文稔、山岡昇司
    • Organizer
      第1回日本HTLV-1学会学術集会
    • Place of Presentation
      東京大学医科学研究所1号館講堂(東京)
    • Year and Date
      2014-08-23
  • [Presentation] 単鎖抗体(scFv)を用いたHTLV-1感染細胞特異的miRNA輸送システムの構築2014

    • Author(s)
      西田亜季, 長門石曉, 中野和民, 山岸誠, 矢持忠徳, 田中勇悦, 津本浩平, 渡邉俊樹
    • Organizer
      第1回日本HTLV-1学会学術集会
    • Place of Presentation
      東京大学医科学研究所1号館講堂(東京)
    • Year and Date
      2014-08-23
  • [Presentation] 細胞外に排出するメタボライトの定量によるATLバイオマーカーの探索2014

    • Author(s)
      池辺詠美, 緒方正男, 手塚健太, ファイフ ニコール, 松本昂, 末岡栄三郎, 堀光雄, 長谷川寛雄, 森下和広, 田中勇悦, 藤澤順一, 西園晃, 伊波英克
    • Organizer
      第1回日本HTLV-1学会学術集会
    • Place of Presentation
      東京大学医科学研究所1号館講堂(東京)
    • Year and Date
      2014-08-23
  • [Presentation] HTLV-1感染者の新鮮及び培養PBMCのTax抗原発現 : Tax抗原簡便フローサイトメトリー(Tax-FCM)を用いた解析2014

    • Author(s)
      田中勇悦, 高橋良明, 藤猪英樹, 宮城拓也, 田中礼子, 友寄毅昭, 福島卓也
    • Organizer
      第1回日本HTLV-1学会学術集会
    • Place of Presentation
      東京大学医科学研究所1号館講堂(東京)
    • Year and Date
      2014-08-23
  • [Presentation] ATL細胞におけるCADM1高発現に必須なNF-κB活性化には、新規制御因子p47の発現低下が関係する2014

    • Author(s)
      西片一朗, 市川朝永, 中畑新吾, 藤井雅寛, 伊波英克, 白神俊幸, 田中勇悦, 井上純一郎, 森下和広
    • Organizer
      第1回日本HTLV-1学会学術集会
    • Place of Presentation
      東京大学医科学研究所1号館講堂(東京)
    • Year and Date
      2014-08-23
  • [Presentation] A new high-throughput method to investigate the clonality of HTLV-1-infected cells based on provirus integration sites2014

    • Author(s)
      Sanaz Firouzi, Tadanori Yamochi, Yosvany López, Yutaka Suzuki, Kenta Nakai, Sumio Sugano, Toshiki Watanabe
    • Organizer
      第1回日本HTLV-1学会学術集会
    • Place of Presentation
      東京大学医科学研究所1号館講堂(東京)
    • Year and Date
      2014-08-23
  • [Presentation] CD30はHTLV-1キャリアにおける異常リンパ球に発現し、核の形態変化に関与する2014

    • Author(s)
      中島誠、矢持忠徳、東原正明、渡邉俊樹、堀江良一
    • Organizer
      第1回日本HTLV-1学会学術集会
    • Place of Presentation
      東京大学医科学研究所1号館講堂(東京)
    • Year and Date
      2014-08-23
  • [Presentation] 血中可溶型CADM1/TSLC1測定によるATL診断法の開発2014

    • Author(s)
      中武彩子、小林行治、中畑新吾、西片一朗、岩永正子、相良康子、北中明、天野正宏、前田宏一、末岡栄三朗、瀬戸山充、岡山昭彦、宇都宮與、下田和哉、渡邉俊樹、森下和広
    • Organizer
      第1回日本HTLV-1学会学術集会
    • Place of Presentation
      東京大学医科学研究所1号館講堂(東京)
    • Year and Date
      2014-08-23
  • [Presentation] HTLV-1キャリアの可溶性CD30血中濃度と成人T細胞白血病発症リスク : 症例対照研究2014

    • Author(s)
      武本重毅、岩永正子、ポルンクナラティオン、相良康子、鵜澤耕治、守田和樹、渡邉俊樹
    • Organizer
      第1回日本HTLV-1学会学術集会
    • Place of Presentation
      東京大学医科学研究所1号館講堂(東京)
    • Year and Date
      2014-08-23
  • [Presentation] 宿主F-boxタンパク質FBXL11はTaxとHBZのユビキチン化を誘導し機能を活性化する2014

    • Author(s)
      安永純一朗、園直希、馬広勇、萩谷啓太、松岡雅雄
    • Organizer
      第1回日本HTLV-1学会学術集会
    • Place of Presentation
      東京大学医科学研究所1号館講堂(東京)
    • Year and Date
      2014-08-22 – 2014-08-24
  • [Presentation] HTLVー1モデルマウスであるHBZ-Tgマウスにおける癌幹細胞の同定と機能解析2014

    • Author(s)
      栗林和華子、水上拓郎、滝澤和也、倉光球、浅田善久、岩間厚志、松岡雅雄、濵口功
    • Organizer
      第1回日本HTLV-1学会学術集会
    • Place of Presentation
      東京大学医科学研究所1号館講堂(東京)
    • Year and Date
      2014-08-22 – 2014-08-24
  • [Presentation] HTLV-1 bZIP factorが惹起する炎症にはIFNγが重要な役割を果たす2014

    • Author(s)
      三田上侑生、安永純一朗、大島孝一、松岡雅雄
    • Organizer
      第1回日本HTLV-1学会学術集会
    • Place of Presentation
      東京大学医科学研究所1号館講堂(東京)
    • Year and Date
      2014-08-22 – 2014-08-24
  • [Presentation] TCF1/LEF1 are T-cell natural HTLV-1 Tax antagonists that restrict viralexpansion in thymus2014

    • Author(s)
      Guangyong Ma, Jun-ichiro Yasunaga, Masao Matsuoka
    • Organizer
      The 1st Annual Meeting of the Japanese Society of HTLV-1and Associated Deceases
    • Place of Presentation
      東京大学医科学研究所1号館講堂(東京)
    • Year and Date
      2014-08-22 – 2014-08-24
  • [Presentation] 京都府民における朝食の主食摂取別栄養摂取量および料理摂取頻度の検討2014

    • Author(s)
      弘田真央、尾﨑悦子、瀬古千佳子、加藤里佳、駒井実香、東あかね
    • Organizer
      第61回日本栄養改善学会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-08-22
  • [Presentation] Helicobacter Pylori感染者における慢性萎縮性胃炎と摂取栄養素量との関連に関する検討2014

    • Author(s)
      瀬古千佳子、弘田真央、加藤里佳、尾﨑悦子
    • Organizer
      第61回日本栄養改善学会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-08-22
  • [Presentation] 老化誘導型核酸医薬の開発に向けて2014

    • Author(s)
      田原栄俊
    • Organizer
      「がん研究分野の特性等を踏まえた支援活動」公開シンポジウム
    • Place of Presentation
      学術総合センター(東京)
    • Year and Date
      2014-08-21
    • Invited
  • [Presentation] Significant associations of abdominal obesity with LYPLAL1 polymorphism (rs4846567) among a general Japanese population : a cross-sectional study2014

    • Author(s)
      Takashi T, Morita E, Kawai S, Sasakabe T, Fukuda N, Sugimoto Y, Suma S, Mokuno J, Nakagawa H, Hishida A, Okada R, Naito M, Hamajima N, Wakai K
    • Organizer
      The 20th IEA World Congress of Epidemiology
    • Place of Presentation
      Anchorage, Alaska, U.S.A.
    • Year and Date
      2014-08-19
  • [Presentation] Dysphagia and dietary intake of Japanese adults : the Shizuoka area in a Japanese multi-institutional collaborative cohort study2014

    • Author(s)
      Naito M, Wakai K, Kawai S, Nakagawa H, Tamura T, Suma S, Sugimoto Y, Fukuda N, Sasakbe T, Okada R, Morita E, Asai Y, Mori A, Hamajima N
    • Organizer
      The 20th IEA World Congress of Epidemiology
    • Place of Presentation
      Anchorage, Alaska, U.S.A.
    • Year and Date
      2014-08-19
  • [Presentation] The Correlation between Microbleeds And Cnm-positive Streptococcus Mutans : A Pilot Survey Study Based On Magnetic Resonance Imaging2014

    • Author(s)
      Nagato Kuriyama, Isao Watanabe, Fumitaro Miyatani, Daisuke Matsui, Etsuko Ozaki, Ryota Nomura, Kazuhiko Nakano and Yoshiyuki Watanabe
    • Organizer
      The 20th IEA World Congress of Epidemiology
    • Place of Presentation
      Anchorage, U.S.A.
    • Year and Date
      2014-08-17 – 2014-08-21
  • [Presentation] Interaction between interleukin1-β gene polymorphism and cigarette smoking on HbA1c in a Japanese general population2014

    • Author(s)
      Nishida Y, Hara M, Nanri H, Nakamura K, Imaizumi T, Sakamoto T, Higaki Y, Taguchi N, Horita M, Shinchi K, Tanaka K
    • Organizer
      20th IEA World Congress of Epidemiology
    • Place of Presentation
      Anchorage, U.S.A.
    • Year and Date
      2014-08-17 – 2014-08-21
  • [Presentation] Perceived stress and coping strategies in relation to body mass index : cross-sectional study of 12,045 Japanese men and women2014

    • Author(s)
      Shimanoe C, Hara M, Nishida Y, Nanri H, Otsuka Y, Nakamura K, Higaki Y, Imaizumi T, Taguchi N, Sakamoto T, Horita M, Shinchi K, Tanaka K
    • Organizer
      20th IEA World Congress of Epidemiology
    • Place of Presentation
      Anchorage, U.S.A.
    • Year and Date
      2014-08-17 – 2014-08-21
  • [Presentation] The association of alcohol intake with serum lipid profile and its modification by ADH1B and ALDH2 polymorphisms : J-MICC Study2014

    • Author(s)
      Sasakabe T, Guang Y, Naito M, Morita E, Kawai S, Okada R, Tamura T, Nakagawa H, Suma S, Fukuda N, Sugimoto Y, Wakai K, Hamajima N
    • Organizer
      The 20th IEA World Congress of Epidemiology
    • Place of Presentation
      Anchorage, Alaska, U.S.A.
    • Year and Date
      2014-08-17
  • [Presentation] Different functional modes of Brn factors contribute to generate diverse projection neurons and glial cells in neocortex2014

    • Author(s)
      Sugitani Y., Sugitani-Yoshida R., Nakai S., Ogawa M., Minowa O., Noda T.
    • Organizer
      Gordon Research Conference, Neural Development 2014
    • Place of Presentation
      Newport, U.S.A.
    • Year and Date
      2014-08-14
  • [Presentation] Chemical biology for drug discovery and target identification2014

    • Author(s)
      掛谷秀昭
    • Organizer
      IUPAC2014 & 248th ACS National Meeting
    • Place of Presentation
      San Francisco, U.S.A.
    • Year and Date
      2014-08-10
    • Invited
  • [Presentation] ヒト肝細胞癌組織における癌幹細胞マーカーとしてのCD44v9の検討2014

    • Author(s)
      石井真美、梯アンナ、魏民、佐谷秀行、鰐渕英機
    • Organizer
      第11回日本病理学会カンファレンス
    • Place of Presentation
      六甲山ホテル(兵庫県・神戸市)
    • Year and Date
      2014-08-01 – 2014-08-02
  • [Presentation] 成人T細胞白血病の基礎免疫研究から発症予防・治療ワクチンへ2014

    • Author(s)
      神奈木真理
    • Organizer
      第18回日本がん免疫学会モーニングセミナー2(臨床)
    • Place of Presentation
      ひめぎんホール(愛媛県、松山市)
    • Year and Date
      2014-08-01
  • [Presentation] Mechanism of leukemogenesis by human T-cell leukemia virus type I2014

    • Author(s)
      Masao Matsuoka
    • Organizer
      The l2th Annual Meeting of Japanese Society of Medical Oncology
    • Place of Presentation
      福岡サンパレス(福岡県・福岡市)
    • Year and Date
      2014-07-17 – 2014-07-19
    • Invited
  • [Presentation] がん関連試料の収集・提供, 神奈川県立がんセンターの腫瘍組織センター事業2014

    • Author(s)
      宮城洋平
    • Organizer
      東京慈恵会医科大学・臨床研究セミナー
    • Place of Presentation
      東京慈恵医科大学(東京)
    • Year and Date
      2014-07-14
  • [Presentation] 骨微小環境における乳がん細胞の増殖に関与するmicroRNAの同定とその機能解析2014

    • Author(s)
      二口充, 深町勝己, 酒々井眞澄
    • Organizer
      第23回日本がん転移学会学術総会シンポジウム
    • Place of Presentation
      金沢市文化ホール・金沢ニューグランドホテル(石川県・金沢市)
    • Year and Date
      2014-07-10
    • Invited
  • [Presentation] ATLの病態と発症に関わる分子機構解明の現状2014

    • Author(s)
      渡邉俊樹
    • Organizer
      HTLV-1セミナー、佐賀県地域医療再生計画事業主催
    • Place of Presentation
      ホテルニューオータニ佐賀(佐賀県・佐賀市)
    • Year and Date
      2014-07-04
    • Invited
  • [Presentation] 疫学研究での小型活動量計による睡眠時間の推計の可能性2014

    • Author(s)
      森田えみ、角谷寛、山田尚登、篠壁多恵、杉本裕香、福田奈菜、須磨紫乃、中川弘子、田村高志、川合紗世、岡田理恵子、菱田朝陽、内藤真理子、浜島信之、若井建志
    • Organizer
      日本睡眠学会第39回定期学術集会
    • Place of Presentation
      あわぎんホール(徳島県・徳島市)
    • Year and Date
      2014-07-03
  • [Presentation] 化学発がん物質のリスク評価における閾値問題2014

    • Author(s)
      福島昭治、魏民、梯アンナ、鰐渕英機
    • Organizer
      第41回日本毒性学会学術年会教育講演
    • Place of Presentation
      神戸コンベンションセンター(兵庫県・神戸市)
    • Year and Date
      2014-07-02 – 2014-07-04
    • Invited
  • [Presentation] 小さな巨人「マイクロRNA」によるがん診断およびがん治療戦略2014

    • Author(s)
      田原栄俊
    • Organizer
      NPO法人国際医科学研究会第8回フォーラム
    • Place of Presentation
      フクラシア東京ステーション(東京)
    • Year and Date
      2014-06-29
  • [Presentation] 生殖細胞の低温保存技術を利用した遺伝子改変マウス研究基盤の構築2014

    • Author(s)
      竹尾透、中潟直己
    • Organizer
      第59回低温生物工学会大会及びセミナー
    • Place of Presentation
      九州大学国際ホール(福岡県・福岡市)
    • Year and Date
      2014-06-28
  • [Presentation] PARP阻害剤をめぐる最近の話題(Year in Review)2014

    • Author(s)
      清宮啓之
    • Organizer
      第18回日本がん分子標的治療学会学術集会
    • Place of Presentation
      仙台市情報・産業プラザ(宮城県・仙台市)
    • Year and Date
      2014-06-27
    • Invited
  • [Presentation] PI3K経路阻害剤(Year in Review)2014

    • Author(s)
      旦慎吾
    • Organizer
      第18回日本がん分子標的治療学会学術集会
    • Place of Presentation
      仙台市情報・産業プラザ(宮城県・仙台市)
    • Year and Date
      2014-06-26
    • Invited
  • [Presentation] Liquid Biopsyによる疾患の診断と核酸医薬の開発の現状2014

    • Author(s)
      田原栄俊
    • Organizer
      PMDA職員研修会
    • Place of Presentation
      独立行政法人医薬品医療機器総合機構(東京)
    • Year and Date
      2014-06-17
    • Invited
  • [Presentation] Identification and analysis of large intergenic non-coding RNAs regulated by p53 family members through a genome-wide analysis of p53 binding sites2014

    • Author(s)
      Idogawa M, Ohashi T, Sasaki Y, Tokio T
    • Organizer
      16th International p53 Workshop
    • Place of Presentation
      Stockholm, Sweden
    • Year and Date
      2014-06-17
  • [Presentation] Genome-based personalized medicine in oncology2014

    • Author(s)
      Tokino T
    • Organizer
      The 18th International Congress of Personalized Medicine
    • Place of Presentation
      札幌コンベンションセンター(北海道・札幌市)
    • Year and Date
      2014-06-14
  • [Presentation] トレモライトの中皮腫発がん性は高いがアンソフィライトの中皮腫発がん性は低い2014

    • Author(s)
      ディルノル・アルキン、岡崎泰昌、周珊瑚、王越、三澤伸明、豊國伸哉
    • Organizer
      第21回日本がん予防学会総会
    • Place of Presentation
      国立がんセンター研究所築地キャンパス(東京)
    • Year and Date
      2014-06-13 – 2014-06-14
  • [Presentation] p53 family network and tumor suppression2014

    • Author(s)
      Sasaki Y, Tamura, M, Takeda K, Idogawa M, Maruyama R, Suzuki H, Shinomura Y, Tokino T
    • Organizer
      The 3rd International Symposium on Genetic Regulation and Targeted Therapy of Cancer and 5th Symposium of A3 Foresight Program
    • Place of Presentation
      Zhangjiajie, China
    • Year and Date
      2014-06-13
  • [Presentation] 「地域住民コホートと老年病研究」(シンポジウム「老年病のコホート研究」)2014

    • Author(s)
      大中佳三
    • Organizer
      第56回日本老年医学会学術集会
    • Place of Presentation
      福岡国際会議場(福岡県、福岡市)
    • Year and Date
      2014-06-12
  • [Presentation] 軽度骨量減少者における動脈壁硬化度の評価とその意義-骨粗鬆症前段階からの骨・血管連関の危険性-2014

    • Author(s)
      栗山長門、尾﨑悦子、松井大輔、渡邉功、渡邊能行
    • Organizer
      第14回臨床血圧脈波研究会
    • Place of Presentation
      品川インターシティホール(東京)
    • Year and Date
      2014-06-07
  • [Presentation] Senescence-associated exosome, the mechanism of secretion and the function2014

    • Author(s)
      Hidetoshi Tahara
    • Organizer
      KSEV2014(Korean Society for ExtracellularVesicles)
    • Place of Presentation
      EwhaCampus Complex, EwhaWomansUniversity, Seoul, Korea
    • Year and Date
      2014-05-30
    • Invited
  • [Presentation] Senescence-associated exosome, the mechanism of secretion and the function2014

    • Author(s)
      Hidetoshi Tahara
    • Organizer
      Symposium on Extracellular Vesicles for Biomedical Applications
    • Place of Presentation
      Clinical Lecture Hall 2, Seoul National Children's Hospital, Seoul, Korea
    • Year and Date
      2014-05-29
    • Invited
  • [Presentation] Functional analysis of the TGF-β pathway in hepatoblasts during mouse hepatic histogenesis.2014

    • Author(s)
      Yokouchi, Y., Yoshii, D., Takeda, H., Suda, H., Inomata, Y., Yamamura, K.
    • Organizer
      第47回日本発生生物学会
    • Place of Presentation
      ウインクあいち(愛知県・名古屋市)
    • Year and Date
      2014-05-27 – 2014-05-30
  • [Presentation] 個体レベルのがん研究支援-in vivo解析の重要性-2014

    • Author(s)
      山村研一
    • Organizer
      平成26年度 文部科学省新学術領域研究生命科学系3分野がん・ゲノム・脳支援活動合同シンポジウム
    • Place of Presentation
      一橋大学一橋講堂学術総合センター2F(東京)
    • Year and Date
      2014-05-27
    • Invited
  • [Presentation] HTLV-1感染が仕掛ける巧妙な罠 : HBZタンパク質 : 成人T細胞白血病(ATL)と原因ウイルス(HTLV-1)「ATL細胞の培養から始まったHTLV-1研究2014

    • Author(s)
      松岡雅雄
    • Organizer
      ATLシンポジウム
    • Place of Presentation
      高新文化ホール(高知県・高知市)
    • Year and Date
      2014-05-24
    • Invited
  • [Presentation] ATL発症に伴う分子異常、そして難病への取り組み2014

    • Author(s)
      渡邉俊樹
    • Organizer
      ATLシンポジウム-成人T細胞白血病(ATL)と原因ウイルス(HTLV-1)「ATL細胞の培養から始まったHTLV-1研究」、高知大学医学部主催
    • Place of Presentation
      高新文化ホール(高知県・高知市)
    • Year and Date
      2014-05-24
    • Invited
  • [Presentation] 認知機能低下を伴う大脳白質病変及びその進行における活性化血小板機能の解析2014

    • Author(s)
      栗山長門、水野敏樹、安池博美、松野浩之、河下映里、田邑愛子、尾崎悦子、松井大輔、渡邉功、近藤正樹、徳田隆彦、大島洋一、吉田誠克、村西学、赤澤健太郎、高田明浩、武田和夫、山田惠、中川正法、渡邊能行
    • Organizer
      第55回日本神経学会
    • Place of Presentation
      福岡国際会議場(福岡県・福岡市)
    • Year and Date
      2014-05-22
  • [Presentation] Xanthohumol impairs autophagosome maturation through direct inhibition of Valosin-containing protein2014

    • Author(s)
      井本正哉
    • Organizer
      RIKEN-Max Planck Joint Research Center for Systems Chemical Biology 3rd Annual Symposium
    • Place of Presentation
      Schloss Ringberg, Germany
    • Year and Date
      2014-05-22
    • Invited
  • [Presentation] アスベスト発がんと過剰鉄 : 動物発がんから発症予防へ2014

    • Author(s)
      豊國伸哉
    • Organizer
      第87回日本産業衛生学会・第84回日本衛生学会
    • Place of Presentation
      岡山コンベンションセンター(岡山県・岡山市)
    • Year and Date
      2014-05-21 – 2014-05-27
    • Invited
  • [Presentation] Direct Detection of Exosome by SP6800 Spectral Analyzer, Direct Detection of Exosome by SP6800 Spectral Analyzer2014

    • Author(s)
      品末聡也、田原栄俊
    • Organizer
      CYTO2014
    • Place of Presentation
      Greater Fort Lauderdale/Broward County Convention Center, Ft. Lauderdale, Florida, U.S.A.
    • Year and Date
      2014-05-19
  • [Presentation] ヒト疾患モデルを用いた病因・病態解析と治療法の検証2014

    • Author(s)
      山村研一
    • Organizer
      第61回日本実験動物学会総会
    • Place of Presentation
      札幌コンベンションセンター(北海道・札幌市)
    • Year and Date
      2014-05-15 – 2014-05-17
    • Invited
  • [Presentation] 可変型遺伝子トラップクローンデータベース[EGTC]の開発と解析2014

    • Author(s)
      荒木正健, 中原舞, 柳井千佳, 山添史雅, 宮家幹子, 森田彩香, 荒木美幸, 岡本瀬幸, 中潟直己, 吉信公美子, 山村研一, 荒木喜美
    • Organizer
      第61回日本実験動物学会総会
    • Place of Presentation
      札幌コンベンションセンター(北海道・札幌市)
    • Year and Date
      2014-05-15 – 2014-05-17
  • [Presentation] 遺伝的モニタリング : 過去・現在・未来2014

    • Author(s)
      加藤秀樹
    • Organizer
      日本実験動物科学技術2014
    • Place of Presentation
      札幌コンベンションセンター(北海道・札幌市)
    • Year and Date
      2014-05-15 – 2014-05-17
    • Invited
  • [Presentation] 遺伝的モニタリングの技法 : (1)近交系およびクローズドコロニーを対象とした品質検査法2014

    • Author(s)
      加藤秀樹
    • Organizer
      日本実験動物科学技術2014
    • Place of Presentation
      札幌コンベンションセンター(北海道・札幌市)
    • Year and Date
      2014-05-15 – 2014-05-17
    • Invited
  • [Presentation] マウス精巣上体尾部冷蔵保存液の開発2014

    • Author(s)
      土山修治、福本紀代子、春口幸恵、近藤朋子、竹下由美、中牟田裕子、梅野智子、高橋郁、古波蔵恵里、竹尾透、Ming-Wen Li、Kristy Kinchen、Jadine Vallelunga、K.C. Kent Lloyd、清水範彦、中潟直己
    • Organizer
      日本実験動物科学技術2014
    • Place of Presentation
      札幌コンベンションセンター(北海道・札幌市)
    • Year and Date
      2014-05-15 – 2014-05-17
  • [Presentation] 遺伝子改変マウス凍結精子とC57BL/6J凍結未受精卵子間での体外受精2014

    • Author(s)
      梅野智子、福本紀代子、春口幸恵、近藤朋子、竹下由美、中牟田裕子、岩本まり、高橋郁、古波蔵恵里、土山修治、竹尾透、中潟直己
    • Organizer
      日本実験動物科学技術2014
    • Place of Presentation
      札幌コンベンションセンター(北海道・札幌市)
    • Year and Date
      2014-05-15 – 2014-05-17
  • [Presentation] Understanding pediatric cancer development by studying induced pluripotency2014

    • Author(s)
      Yamada Y.
    • Organizer
      ADVANCES IN NEUROBLASTOMA RESEARCH
    • Place of Presentation
      Colonge, Germany
    • Year and Date
      2014-05-13 – 2014-05-16
    • Invited
  • [Presentation] Connectivity mapデータベースを利用した化合物スクリーニングのアルゴリズム開発2014

    • Author(s)
      牛嶋大、冨田章弘、斎藤さかえ、野田哲生、松浦正明
    • Organizer
      文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウム アカデミアからの抗がん剤創薬に向けて―天然物の有効利用
    • Place of Presentation
      万国津梁館(沖縄県・名護市)
    • Year and Date
      2014-05-12
  • [Presentation] ヒトがん細胞パネルJFCR39による化合物の活性評価2014

    • Author(s)
      山崎佳波、矢守隆夫、旦慎吾
    • Organizer
      文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
    • Place of Presentation
      万国津梁館(沖縄県・名護市)
    • Year and Date
      2014-05-12
  • [Presentation] 化学療法基盤支援活動におけるプロテインキナーゼ阻害剤活性の評価(Ⅱ)2014

    • Author(s)
      福山まり、深澤秀輔
    • Organizer
      文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
    • Place of Presentation
      万国津梁館(沖縄県・名護市)
    • Year and Date
      2014-05-12
  • [Presentation] 化学療法基盤支援活動「プロテインキナーゼ(PK)阻害活性の評価」2014

    • Author(s)
      西谷直之、岩尾正倫、上原至雅
    • Organizer
      文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
    • Place of Presentation
      万国津梁館(沖縄県・名護市)
    • Year and Date
      2014-05-12
  • [Presentation] サブタイプ選択的なHDACアッセイ系を用いたbicyclic depsipeptide HDAC阻害剤のサブタイプ選択性の評価2014

    • Author(s)
      中田明子、伊藤昭博、加藤正、吉田稔
    • Organizer
      文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
    • Place of Presentation
      万国津梁館(沖縄県・名護市)
    • Year and Date
      2014-05-12
  • [Presentation] 化合物活性予測のための遺伝子発現データベース構築2014

    • Author(s)
      田代悦、大嶽弘之、井本正哉
    • Organizer
      文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
    • Place of Presentation
      万国津梁館(沖縄県・名護市)
    • Year and Date
      2014-05-12
  • [Presentation] 再燃性前立腺がんにおける短鎖型アンドロゲン受容体の役割とその制御物質2014

    • Author(s)
      岡部幸子、馬島哲夫、清宮啓之
    • Organizer
      文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
    • Place of Presentation
      万国津梁館(沖縄県・名護市)
    • Year and Date
      2014-05-12
  • [Presentation] 化学療法基盤支援活動が無償配布する化合物ライブラリー2014

    • Author(s)
      川田学
    • Organizer
      文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
    • Place of Presentation
      万国津梁館(沖縄県・名護市)
    • Year and Date
      2014-05-12
  • [Presentation] 理研天然化合物バンクNPDepoの構築と活用2014

    • Author(s)
      長田裕之
    • Organizer
      文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
    • Place of Presentation
      万国津梁館(沖縄県・名護市)
    • Year and Date
      2014-05-12
  • [Presentation] 理化学研究所天然化合物(NPDepo)が提供する創薬研究支援2014

    • Author(s)
      斎藤臣雄、近藤恭光、長田裕之
    • Organizer
      文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
    • Place of Presentation
      万国津梁館(沖縄県・名護市)
    • Year and Date
      2014-05-12
  • [Presentation] がん分子標的薬開発の状況とシード探索法2014

    • Author(s)
      水上民夫
    • Organizer
      文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
    • Place of Presentation
      万国津梁館(沖縄県・名護市)
    • Year and Date
      2014-05-12
  • [Presentation] がん分子標的創薬を指向した低酸素誘導因子(HIF)阻害剤の探索・開発研究2014

    • Author(s)
      嶋田清香、吉村彩、安田順信、高橋伸明、西村慎一、服部明、掛谷秀昭
    • Organizer
      文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
    • Place of Presentation
      万国津梁館(沖縄県・名護市)
    • Year and Date
      2014-05-12
  • [Presentation] 高速細胞スキャナーを用いた3次元培養による抗がん剤スクリーニング法の開発2014

    • Author(s)
      水上民夫、東郷有希、細井美穂、長谷川慎、佐々木隆造、藤本博己、生藤邦夫
    • Organizer
      文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
    • Place of Presentation
      万国津梁館(沖縄県・名護市)
    • Year and Date
      2014-05-12
  • [Presentation] タンパク質脂質修飾酵素によるWnt/β-cateninシグナルの制御2014

    • Author(s)
      西谷直之、奥裕介、上原至雅
    • Organizer
      文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
    • Place of Presentation
      万国津梁館(沖縄県・名護市)
    • Year and Date
      2014-05-12
  • [Presentation] ゴルジ体阻害化合物の3D-QSARに基づくFragment-Based In Silico Screening2014

    • Author(s)
      内田太郎、山乙教之、広野修一、江頭直樹、椎名勇、藤本晶子、守谷潤、大橋愛美、旦慎吾、矢守隆夫
    • Organizer
      文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
    • Place of Presentation
      万国津梁館(沖縄県・名護市)
    • Year and Date
      2014-05-12
  • [Presentation] 全合成ゴルジ阻害剤M-COPAの抗がん活性2014

    • Author(s)
      大橋愛美、椎名勇、旦慎吾、矢守隆夫
    • Organizer
      文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
    • Place of Presentation
      万国津梁館(沖縄県・名護市)
    • Year and Date
      2014-05-12
  • [Presentation] 乳がん細胞の増殖におけるメチル化リジン結合タンパク質CBX2の重要性の解明2014

    • Author(s)
      伊藤昭博、波多野稔子、Muhammad Muddassar、Kam Zhan、吉田稔
    • Organizer
      文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
    • Place of Presentation
      万国津梁館(沖縄県・名護市)
    • Year and Date
      2014-05-12
  • [Presentation] 神経膠腫幹細胞に対するテロメスタチン誘導体の選択的な抗腫瘍効果2014

    • Author(s)
      中村貴大、岡部幸子、飯田圭介、矢守隆夫、新家一男、中野伊知郎、長澤和夫、清宮啓之
    • Organizer
      文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
    • Place of Presentation
      万国津梁館(沖縄県・名護市)
    • Year and Date
      2014-05-12
  • [Presentation] Biogenesis and biological activity of exosomes in replicative senescent cells2014

    • Author(s)
      Megumi Okada, Ayumi Nakamura, Misa Muneoka, Nao Nitta, Hidetoshi Tahara
    • Organizer
      ISEV(INTERNATIONAL SOCIETY FOR EXTRACELLULAR VESICLES)2014
    • Place of Presentation
      ロッテルダム、オランダ
    • Year and Date
      2014-05-01
  • [Presentation] 骨微小環境におけるがん細胞の増殖メカニズム2014

    • Author(s)
      二口充
    • Organizer
      第87回日本内分泌学会学術総会シンポジウム
    • Place of Presentation
      福岡サンパレス(福岡県・福岡市)
    • Year and Date
      2014-04-26
    • Invited
  • [Presentation] 東大医科研における橋渡し研究とその発展2014

    • Author(s)
      今井浩三
    • Organizer
      第103回日本病理学会総会 特別企画
    • Place of Presentation
      広島国際会議場フェニックスホール(広島県・広島市)
    • Year and Date
      2014-04-24 – 2014-04-26
    • Invited
  • [Presentation] マウス肺扁平上皮癌において気管支肺胞幹細胞がオリジンである可能性2014

    • Author(s)
      山野荘太郎、魏民、藤岡正喜、鰐渕英機
    • Organizer
      第103回日本病理学会総会
    • Place of Presentation
      広島国際会議場(広島県・広島市)
    • Year and Date
      2014-04-24 – 2014-04-26
  • [Presentation] ヒト肝細胞癌におけるLC-MS/MS及びin vitro機能解析を用いた新規特異的候補分子ターゲットの検討2014

    • Author(s)
      梯アンナ、桑江優子、石井真美、魏民、鰐渕英機
    • Organizer
      第103回日本病理学会総会
    • Place of Presentation
      広島国際会議場(広島県・広島市)
    • Year and Date
      2014-04-24 – 2014-04-26
  • [Presentation] EHEN誘発ラット腎発がんにおいて内因性NADPH oxidase阻害剤apocy-ninは抑制作用を有する2014

    • Author(s)
      三島胡桃、山野荘太郎、藤岡正喜、魏民、鰐渕英機
    • Organizer
      第103回日本病理学会総会
    • Place of Presentation
      広島国際会議場(広島県・広島市)
    • Year and Date
      2014-04-24 – 2014-04-26
  • [Presentation] 非B非C型肝細胞がんの病理学的解析2014

    • Author(s)
      神田浩明、鹿取正道、山本智理子、マハムットヤセン、齋浦明夫、石川雄一、加藤洋、北川知行
    • Organizer
      第103回日本病理学会総会
    • Place of Presentation
      広島国際会議場(広島県・広島市)
    • Year and Date
      2014-04-24 – 2014-04-26
  • [Presentation] 発がん要因としての酸化ストレス シンポジウム1 : 腫瘍病理学の真髄2014

    • Author(s)
      豊國伸哉
    • Organizer
      第103回日本病理学会総会
    • Place of Presentation
      広島国際会議場(広島県・広島市)
    • Year and Date
      2014-04-24
    • Invited
  • [Presentation] ヒト腫瘍の原因について病理はなにができるか2014

    • Author(s)
      椙村春彦
    • Organizer
      第103回日本病理学会総会
    • Place of Presentation
      広島国際会議場(広島県・広島市)
    • Year and Date
      2014-04-24
  • [Presentation] 疾患感受性遺伝子による2型糖尿病発症予測の検討2014

    • Author(s)
      大中佳三、河野倫子、山本健、河手久弥、野村政壽、古野純典、井口登與志、高柳涼一
    • Organizer
      第87回日本内分泌学会学術集会
    • Place of Presentation
      福岡国際会議場(福岡県・福岡市)
    • Year and Date
      2014-04-24
  • [Presentation] ATL発症とプログレッションの分子基盤解明の試み2014

    • Author(s)
      渡邉俊樹
    • Organizer
      ATL small meeting、協和発酵キリン(株)主催
    • Place of Presentation
      ホテルモントレー仙台(宮城県・仙台市)
    • Year and Date
      2014-04-18
    • Invited
  • [Presentation] Growth of malignant tumor in the bone microenvironment2014

    • Author(s)
      Futakuchi, M.
    • Organizer
      2014 Seoul National University Cancer Research Institute, Cancer Symposium
    • Place of Presentation
      Mokpo, Korea
    • Year and Date
      2014-04-16
    • Invited
  • [Presentation] 東京大学医科学研究所におけるTRの現状と展望. シンポジウム2「我が国におけるトランスレーショナルリサーチの現状とこれからの展望」2014

    • Author(s)
      今井浩三
    • Organizer
      第51回日本臨床分子医学会学術集会
    • Place of Presentation
      東京国際フォーラム(東京)
    • Year and Date
      2014-04-11 – 2014-04-12
    • Invited
  • [Presentation] Human colorectal cancer marker PC(16:0/16:1)induces cell growth by activating Akt and Erk pathways2014

    • Author(s)
      Nobuya Kurabe, Toshio Nakamura, Kiyotaka Kurachi, Tomoaki Kahyo, Kazuya Shinmura, Mitsutoshi Setou, Haruhiko Sugimura
    • Organizer
      The 105th AACR Annual Meeting
    • Place of Presentation
      San Diego, U.S.A.
    • Year and Date
      2014-04-07
  • [Presentation] Forkhead transcription factor FOXFI is a novel target gene of the p53 family and regulates cancer cell migration and invasiveness2014

    • Author(s)
      Tokino T, Tamura M, Idogawa M, Sasaki Y
    • Organizer
      American Association of Cancer Research (AACR) Annual Meeting
    • Place of Presentation
      San Diego, U.S.A.
    • Year and Date
      2014-04-06
  • [Book] 実験動物の感染症と微生物モニタリング2015

    • Author(s)
      高倉彰, 他
    • Total Pages
      102
    • Publisher
      ㈱アドスリー
  • [Book] 臨床病理63(1), ヒトがん関連試料の提供事業に於ける質の管理 : 神奈川がん臨床研究・情報機構での経験から2015

    • Author(s)
      宮城洋平
    • Total Pages
      111-118
    • Publisher
      克誠堂出版
  • [Book] 最新がん薬物療法学2015

    • Author(s)
      北川光洋、田代悦、井本正哉
    • Total Pages
      704(90-96)
    • Publisher
      (株)日本臨床社
  • [Book] ゲノム解析に基づく新しい分子標的治療 : ゲノムワイドな解析および統合的解析による前立腺がん幹細胞の分子標的探索(「がん分子標的治療」)2015

    • Author(s)
      馬島哲夫、清宮啓之
    • Total Pages
      116(52-56)
    • Publisher
      メディカルレビュー社
  • [Book] 「繊維性ナノマテリアルの発がん機構」-職業・環境発がん : メカニズムと病理-『病理と臨床』2014年6月号(32巻6号)2014

    • Author(s)
      豊國伸哉(編集)
    • Total Pages
      116
    • Publisher
      文光堂
  • [Book] 「浸潤と転移」『新臨床腫瘍学(改訂第4版)-がん薬物療法専門医のために-』2014

    • Author(s)
      二口充
    • Total Pages
      4
    • Publisher
      南光堂
  • [Book] 酸化ストレスを標的とした治療開発2014

    • Author(s)
      塩田真己、横溝晃、内藤誠二
    • Total Pages
      2131-2135
    • Publisher
      日本臨牀
  • [Book] 「成人T細胞白血病に対する免疫療法~AZT/IFN-α、骨髄移植、樹状細胞ワクチン~」『血液フロンティア』2014年11月号(Vol.24 No.11)2014

    • Author(s)
      神奈木真理、長谷川温彦、金原秀一、末廣陽子
    • Total Pages
      1631-1638
    • Publisher
      医薬ジャーナル社
  • [Book] 血液内科医・皮膚科医のための統合ATL診療ガイドライン解説書2014、124巻12号2014

    • Author(s)
      石田高司、伊藤旭、戸倉新樹、田中淳司、鵜池直邦、飛内賢正、塚崎邦弘
    • Total Pages
      2275-2279
    • Publisher
      日本皮膚科学会雑誌
  • [Book] Human T-cell leukemia virus type 1 : pathogenesis and host immune response. Viruses and human cancers, edited by Hudnall, SD2014

    • Author(s)
      Yasunaga JI and Matsuoka M
    • Total Pages
      229-262
    • Publisher
      Springer
  • [Book] 「ヒトT細胞白血病ウイルス1型感染症(Human T-cell leukemia virus type Infection)」J. RNAウイルス感染症、Ⅲ章. 主要な感染症(原因微生物毎)、-感染症診療update-『日本医師会雑誌』143巻・特別号(2)2014

    • Author(s)
      渡邉俊樹
    • Total Pages
      394-397
    • Publisher
      日本医師会
  • [Book] 「マイクロRNA発現異常とHTLV-1による成人T細胞白血病(ATL)発症」特集マイクロRNAと血液疾患『血液内科』68(6)2014

    • Author(s)
      渡邉俊樹
    • Total Pages
      781-785
    • Publisher
      科学評論社
  • [Book] The Role of DNA Methylation in the Genetics and Epigenetics of Multiple Myelome2014

    • Author(s)
      Yasui H, Ishida T, Imai K
    • Total Pages
      249(147-156)
    • Publisher
      Nova Science Publishers
  • [Book] 特集オートファジーに挑むケミカルバイオロジー「天然物化学とケミカルバイオロジーの挑戦」2014

    • Author(s)
      田代悦、井本正哉
    • Total Pages
      79(22-27)
    • Publisher
      (株)化学工業社
  • [Book] がん細胞パネルーバイオインフォマティクスによる新たな分子標的抗がん剤創薬とバイオマーカー探索(「最新がん薬物療法学-がんの薬物療法の最新知見-」)2014

    • Author(s)
      旦慎吾
    • Total Pages
      710(102-108)
    • Publisher
      日本臨牀
  • [Book] Clinical Genomicsを目指した半導体NGSによるがんゲノム解析. 実験医学32(11)2014

    • Author(s)
      丸喜明、佐々木泰史、中村友紀、横井左奈、大平美紀、時野隆至、永瀬浩喜
    • Total Pages
      8ページ(1781-1788)
    • Publisher
      羊土社
  • [Book] 大腸腺腫と大腸鋸歯状病変における遺伝子異常と生活習慣の関連2014

    • Author(s)
      五十嵐央祥、能正勝彦、伊藤美樹、篠村恭久
    • Total Pages
      7ページ(605-611)
    • Publisher
      先端医学社
  • [Remarks] がん研究分野の特性等を踏まえた支援活動

    • URL

      http://ganshien.umin.jp/

  • [Remarks] がん研究分野の特性等を踏まえた支援活動 ホーム>研究紹介>インタビュー>豊國伸哉教授

    • URL

      http://ganshien.umin.jp/research/main/toyokuni/index.html

  • [Remarks] J-MICC STUDY/日本多施設共同コーホート研究(ジェイミック スタディ)

    • URL

      http://www.jmicc.com

  • [Remarks] 京都府立医科大学大学院医学研究科 地域保健医療疫学のホームページ

    • URL

      http://www.f.kpu-m.ac.jp/k/epid/index.html

  • [Remarks] J-MICC Study(ジェイミック・スタディ)佐賀フィールドとは

    • URL

      http://www.prevent.med.saga-u.ac.jp/jmiccsaga.html

  • [Remarks] 鹿児島大学大学院医歯学総合研究科 国際島嶼医療学講座「研究の紹介」

    • URL

      http://www.kufm.kagoshima-u.ac.jp/~islands/

  • [Remarks] 国際教養学部開設記念シンポジウム(5/13)

    • URL

      http://www.juntendo.ac.jp/event/20150513-00000102.html

  • [Remarks] 研究紹介がん疫学・予防支援活動「倫理的・法的・社会的諸問題(ELSI)」の支援

    • URL

      http://publichealth.med.hokudai.ac.jp/research/

  • [Remarks] J-MICC Study 静岡地区ホームページ

    • URL

      http://www.med.nagoya-u.ac.jp/yobo/jmicc_shizuoka/

  • [Remarks] J-MICC Study 大幸研究ホームページ

    • URL

      http://www.med.nagoya-u.ac.jp/yobo/jmicc/

  • [Remarks] 浜松医大病理学講座がん支援活動ホームページ

    • URL

      http://www.hama-med.ac.jp/uni_education_igakubu_igaku_byouril_ganshienkenkyu.html

  • [Remarks] サンパウロ日系人研究

    • URL

      http://epi.ncc.go.jp/spF/index.html

  • [Remarks] Laboratory of Virus Control Institute for Virus Research Kyoto University「研究内容」

    • URL

      http://www.virus.kyoto-u.ac.jp/Lab/VirusControl/aboutus.html

  • [Remarks] SCADS文部科学省新学術領域研究『がん研究分野の特性等を踏まえた支援活動』化学療法基盤支援活動

    • URL

      http://scads.jfcr.or.jp/index.html

  • [Patent(Industrial Property Rights)] 染色バスケット2014

    • Inventor(s)
      加茂隆春・椙村春彦・門畑一久
    • Industrial Property Rights Holder
      浜松医科大学
    • Industrial Property Rights Type
      特許特願2014-157406
    • Industrial Property Number
      特願2014-157406
    • Filing Date
      2014-08-01
  • [Patent(Industrial Property Rights)] HTLV-1関連疾患の予防及び/又は治療用ワクチン2014

    • Inventor(s)
      松岡雅雄、菅田謙治
    • Industrial Property Rights Holder
      京都大学
    • Industrial Property Rights Type
      特許特願2014-155855
    • Industrial Property Number
      特願2014-155855
    • Filing Date
      2014-07-31

URL: 

Published: 2016-06-01   Modified: 2016-06-08  

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