2012 Fiscal Year Final Research Report
Control of body weight based on the interaction between energy metabolism and sleep
| Project/Area Number |
22300233
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied health science
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| Research Institution | University of Tsukuba |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
SATOH Makoto 筑波大学, 医学医療系, 教授 (50242409)
NAGASAKA Shoichiro 自治医科大学, 医学部, 准教授 (00296112)
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| Project Period (FY) |
2010 – 2012
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| Keywords | ヒューマン・カロリメータ / 肥満 / 睡眠 / 運動処方 |
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| Research Abstract |
Late evening meal delays onset of sleep, enhances average blood glucose over 24 h, but does not support that late evening meal reduces 24 h energy expenditure.Compared with exercise performed in the postprandial state, exercise performed in the post-absorptive state oxidized more fat and saved more carbohydrate in the body, without affecting 24 h energy expenditure. Nonexercise activity thermogenesis plays an important role in long-range negative correlation and hence long-term blood glucose control in healthy young adults. Thus difference in life style affect 24 h energy metabolism and sleep. Patients with sleep apnea syndrome oxidized less fat during sleep, and their energy expenditure was slightly higher than that of control subjects.
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Research Products
(10 results)
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[Journal Article] Proteasome dysfunction mediates obesity-induced endoplasmic reticulum stress and insulin resistance in the liver.2013
Author(s)
Otoda T, T.Takamura, H.Misu, T.Ota, S. Murata, H.Hayashi, H.Takayama, A. Kikuchi, T.Kanamori, K.R.Shima, F.Lan, T.Takeda, S.Kurita, K.Ishikura, Y.Kita, K.Iwayama, K.Kato, M.Uno, Y.Takeshita, M.Yamamoto, K.Tokuyama, S.Iseki, K. Tanaka, S.Kaneko.
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Journal Title
Diabetes
Volume: 62巻
Pages: 811-824
Peer Reviewed
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[Journal Article] The lack of long-range negative correlations in glucose dynamics is associated with worse glucose control in diabetes mellitus patients.2012
Author(s)
Ogata H, K.Tokuyama, S.Nagasaka, T.Tsuchita, I.Kusaka, S.Ishibashi, H.Suzuki, N.Yamada, K.Hamano, K.Kiyono, Z.R.Struzik, Y.Yamamoto
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Journal Title
Metabolism
Volume: 61巻
Pages: 1041-1050
Peer Reviewed
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[Journal Article] Acute effect of late evening meal on diurnal variation of blood glucose and energy metabolism.2011
Author(s)
Sato M, K.Nakamura, H.Ogata, A.Miyashita, S.Nagasaka, N.Omi, S.Yamaguchi, M.Hibi, T.Umeda, S.Nakaji, K.Tokuyama
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Journal Title
Obesity Research and Clinical Practice
Volume: 5巻
Pages: e220- e228
Peer Reviewed
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