2012 Fiscal Year Final Research Report
Synthesis of nioactive natural products having highly functionalizsd torsional structures
| Project/Area Number |
22350045
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Synthetic chemistry
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| Research Institution | Waseda University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
TATSUTA Kuniaki 早稲田大学, 名誉教授・栄誉フェロー (40051627)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 有機合成化学 / 生理活性 / 天然物 / 創薬 / 全合成 |
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| Research Abstract |
Synthetic studies on polycyclic and bioactive natural products having torsional and specific structures were performed. The first total syntheses of some natural products have been achieved, and the specific skeletons of other polyciclic natural products have been constructed. Additionally, new methodologies including the cyclization with thiolactones, the construction of a xanthone using chromonecarboxaldehyde and unsaturated malonate, and the short-step synthesis of reduced propionates have been developed.
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Research Products
(31 results)
