2013 Fiscal Year Final Research Report
Elucidation of mechanisms involved in formation of yolk granules and lipid droplets in fish
| Project/Area Number |
22380103
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
General fisheries
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| Research Institution | Hokkaido University |
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Principal Investigator |
HARA Akihiko 北海道大学, -, 名誉教授 (40091483)
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| Co-Investigator(Kenkyū-buntansha) |
TODO Takashi 北海道大学, 大学院・水産科学研究院, 准教授 (60303111)
HIRAMATSU Naoshi 北海道大学, 大学院・水産科学研究院, 准教授 (10443920)
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| Project Period (FY) |
2010-04-01 – 2014-03-31
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| Keywords | リポ蛋白質 / 魚類繁殖生理 / ビテロジェニン / リポ蛋白質受容体 / 蛋白質相互作用 / 卵黄形成 / 油球形成 / 卵成長 |
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| Research Abstract |
The objective of this study is to elucidate mechanisms involved in the formation of "yolk granules/globules (YGs)" and "lipid droplets (LDs)", which are major components of fish egg yolk. Results revealed profiles of YG precursors (vitellogenins) and LD precursors (various lipoproteins), as well as their corresponding ovarian receptors (lipoprotein receptors); these findings resulted in constructing and proposing a novel and complicated model for fish yolk formation, which will also help to progressively regulate oocyte growth and improve egg quality in aquaculture fishes in future.
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