2012 Fiscal Year Final Research Report
Development of clinical marker to predict longitudinal prognosis of early psychosis
| Project/Area Number |
22390219
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Psychiatric science
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
MATSUOKA Hiroo 東北大学, 大学院・医学系研究科, 教授 (00173815)
MUGIKURA Syunji 東北大学, 大学院・医学系研究科, 講師 (20375017)
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| Research Collaborator |
TOMITA Hiroaki 東北大学, 災害科学国際研究所, 教授 (90295064)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 早期精神病 / 早期介入 / ARMS / 統合失調症 / 診断 |
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| Research Abstract |
To develop useful and reliable clinical markers to predict the longitudinal prognosis of early psychosis, we investigated clinical variables of at risk mental state (ARMS) and first episode psychosis (FEP) at intake and follow-up. In our sample of 116 patients with ARMS, 14% transited to psychosis. Cognitive performance improved to a greater extent in patients with ARMS than in those with FEP. The present findings indicate the importance of using multiple clinical variables in combination to assess and predict the functionalprognosis of early psychosis.
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[Journal Article] Prefrontal and Striatal Volumes in Monozygotic Twins Concordant and Discordant forSchizophrenia2012
Author(s)
Ettinger U, Schmechtig A, Toulopoulou T, Borg C, Orrells C, Owens S, Matsumoto K, van Haren NE, Hall MH, Kumari V, McGuire PK, Murray RM, Picchioni M.
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Journal Title
Schizophrenia Bulletin
Volume: 38
Pages: 192-203
DOI
Peer Reviewed
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[Presentation] Association of deficits in theory of mind and functioning in at-risk mental states and first-episode psychosis2012
Author(s)
Noriyuki Ohmuro, Kazunori Matsumoto, Masahiro Katsura, Atsushi Sakuma, Kunio Iizuka, Tatsuo Kikuchi, Chika Obara, Yumiko Hamaie, Tomohiro Uchida, Emi Sunakawa, Fumiaki Ito, Hiroo Matsuoka.
Organizer
8th International Conference on Early Psychosis
Place of Presentation
From Neurobiology to Public Policy San Francisco,USA
Year and Date
2012-10-11
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[Presentation] 名取EIプロジェクト:宮城県立精神医療センターを中心とした早期介入プロジェクト2012
Author(s)
大野高志,船越俊一,角藤芳久,谷口宏,三塚杏子,野村綾,横川信弘,齋藤和子,香山明美,石黒奈々子,大室則幸,桂雅宏,濱家由美子,小高晃,松本和紀,松岡洋夫
Organizer
第108回日本精神神経学会学術総会
Place of Presentation
北海道
Year and Date
2012-05-26
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