2012 Fiscal Year Final Research Report
New application in treatment of head and neck cancer using genome and proteome analysis
| Project/Area Number |
22390314
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Hokkaido University |
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Principal Investigator |
FUKUDA Satoshi 北海道大学, 北海道大学病院, 教授 (20125347)
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| Co-Investigator(Kenkyū-buntansha) |
HOMMA Akihiro 北海道大学, 北海道大学病院, 講師 (30312359)
HATAKEYAMA Shigetugu 北海道大学, 大学院・医学研究科, 教授 (70294973)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 頭頸部癌 / トランスクリプトーム / EGFR / NF-kB |
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| Research Abstract |
In this study, we could get the genome, proteome and microRNAs profile using the head and neck cancer samples from our institute. Furthermore, salivary grand samples could be added to this study and the molecular which showed difference depending on prognosis were confirmed their expression with the immunohistochemical methods. A lot of data were presented on meetings of American head and neck society, Asian society of head and neck, and other international meetings.We got the tremendous volume of data of head and neck cancer, so we need to continue the data-mining and the examination of protein-protein reaction to apply clinically.
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[Journal Article] Combined modality therapy for laryngeal cancer with superselective intra-arterial cisplatin infusion and concomitant radiotherapy2012
Author(s)
Taki S, Homma A, Suzuki F, Oridate N, Hatakeyama H, Mizumachi T, Kano S, Furusawa J, Sakashita T, Inamura N, Yoshida D, Onimaru R, Shirato H, Fukuda S
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Journal Title
Int J Clin Oncol
Volume: 17
Pages: 441-446
Peer Reviewed
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[Journal Article] Concomitant weekly Cisplatin and radiotherapy for head and neck cancer2011
Author(s)
Homma A, Inamura N, Oridate N, Suzuki S, Hatakeyama H, Mizumachi T, Kano S, Sakashita T, Onimaru R, Yasuda K, Shirato H, Fukuda S
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Journal Title
Jpn J Clin Onco
Volume: l41
Pages: 980-986
Peer Reviewed
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[Journal Article] Superselective arterial cisplatin infusion with concomitant radiation therapy for base of tongue cancer2011
Author(s)
Kano S, Homma A, Oridate N, Suzuki F, Hatakeyama H, Mizumachi T, Furusawa J, Sakashita T, Yoshida D, Onimaru R, Shirato H, Fukuda S
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Journal Title
Oral Oncol
Volume: 47
Pages: 665-670
Peer Reviewed
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[Presentation] < Symposium1 > Nasopharyngeal cancer and nasal cavity and paranasal sinus-Superselective Intra-arterial Infusion of Cisplatin and Concomitant Radiotehrapy for Paranasal Sinus Cancers2011
Author(s)
Homma A, Oridate N, Sakashita T, Yoshida D, Onimaru R, Tsuchiya K, Yasuda K, Suzuki S, Hatakeyama H, Mizumachi T, Kano S, Shirato H, Fukuda S
Organizer
ANA CROWNE PLAZA KOBE
Place of Presentation
Kobe, Japan
Year and Date
20111208-09
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[Presentation] Rapid superselective high-dose cisplatin infusion with concomitant radiotherapy for squamous cell carcinoma of the nasal vestibule : a report of two cases2011
Author(s)
Homma A, Suzuki F, Hatakeyama H, Sakashita T, Oridate N, Yoshida D, Onimaru R, Tsuchiya K, Yasuda K, Shirato H, Fukuda S
Organizer
The 2nd Asian Society of Head & Neck Oncology Meeting
Place of Presentation
Grand Hyatt, Goa, India
Year and Date
20111006-09
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[Presentation] < Symposium 9>Up to date therapy for sinonasal malignant tumors-Superselective intra-arterialchemotherapy with concurrent radiotherapy for sinonasal malignant tumors2011
Author(s)
Homma A, Sakashita T, Oridate N, Mizumachi T, Kano S, Furusawa J, Inamura N, Taki S, Fukuda S
Organizer
14th International Rhinologic Society, 30th International Symposium Infection and Allergy of the Nose
Place of Presentation
ANA Intercontinental hotel Tokyo, Tokyo, Japan
Year and Date
20110920-23
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[Presentation] The efficacy of superselective intra-arterial infusion for unresectable carcinoma of the paranasal sinuses2010
Author(s)
Homma A, Oridate N, Suzuki F, Sakashita T, Furusawa J, Taki S, Inamura N, Mizumachi T, Kano S, Yoshida D, Onimaru R, Fukuda S
Organizer
The American Head and Neck Society 2010Research Workshop
Place of Presentation
Hyatt RegencyCrystal City, Arlington, VA, USA
Year and Date
20101028-30
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