2012 Fiscal Year Final Research Report
Study of the head and neck organ regeneration technology using iPS cells
| Project/Area Number |
22390317
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Otorhinolaryngology
|
|---|
| Research Institution | Fukushima Medical University |
|---|
Principal Investigator |
OMORI Koichi 福島県立医科大学, 医学部, 教授 (10233272)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
NAKAMURA Tatuo 京都大学, 再生医科学研究所, 准教授 (70227908)
WADA Ikuo 福島県立医科大学, 医学部, 教授 (40182969)
|
|---|
| Project Period (FY) |
2010 – 2012
|
| Keywords | 頭頸部外科学 / 再生医学 / iPS 細胞 |
|---|
| Research Abstract |
The purpose of this study is to establish a technique for differentiation from iPS cells into head and neck tissues in order to regenerate head and neck organs. The scaffold involving chondrogenic cells which were differentiated from iPS cells was implanted into the tracheal defect of animal models. Regeneration of the cartilage tissue was histologically recognized. Regeneration of the epithelial-like tissue was also recognized through embryoid bodiesfrom iPS cells. This is the first study to demonstrate the potential of iPS cells for the regeneration of the head and neck tissues.
|
