• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

2012 Fiscal Year Final Research Report

Reconstruction of Jaw Bone with 3 dimension scaffold treated by functionalized carbon nano-material

Research Project

  • PDF
Project/Area Number 22390361
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Prosthetic dentistry
Research InstitutionHokkaido University

Principal Investigator

YOKOYAMA Atsuro  北海道大学, 大学院・歯学研究科, 教授 (20210627)

Co-Investigator(Kenkyū-buntansha) AKASAKA Tsukasa  北海道大学, 大学院・歯学研究科, 准教授 (00360917)
YAMAMOTO Satoru  北海道大学, 大学院・歯学研究科, 助教 (10344524)
TAKITA Hiroko  北海道大学, 大学院・歯学研究科, 助教 (30125330)
SATO Yoshinori  東北大学, 大学院・環境科学研究科, 准教授 (30374995)
YASUDA Motoaki  北海道大学, 大学院・歯学研究科, 准教授 (90239765)
Co-Investigator(Renkei-kenkyūsha) SHIBA Kiyotaka  癌研究所, タンパク創製研究部, 部長 (40196415)
YUDASAKA Masako  産業技術総合研究所, ナノチューブ応用研 究センター, チーム長 (70159226)
Project Period (FY) 2010 – 2012
Keywordsカーボンナノマテリアル / 生体材料 / 骨形成 / b-FGF / スタチン / チタン
Research Abstract

Functionalized carbon nanomaterials were developed by covalent bond of b-FGF to multiwalled carbon nanotubes and absorption of simvastatin to carbon nanohorns, and effects of them on bone formation were evaluated by animal experiments. Extensive bone formation was observed in the scaffolds with functionalized carbon nanomaterials in comparison with normal carbon nanomaterials. Also, biocompatibility carbon nanomaterials was observed by animal experiments for a long term.

  • Research Products

    (7 results)

All 2012 2011 2010

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (3 results) Book (1 results)

  • [Journal Article] nanotube- coati ng of 3D col l agen scaf f ol ds f or bone ti ssue engineering2011

    • Author(s)
      Hi rat a E, Uo M, Taki t a H, Akasaka T, Wat ari F, Yokoyama A. Mul ti wal l ed carbon
    • Journal Title

      Carbon

      Volume: 49 Pages: 3284-91

    • Peer Reviewed
  • [Journal Article] Carbon nanohorns accel erate bone regenerat i on i n rat cal vari al bone def ect2011

    • Author(s)
      Kasai T, Mat sumura S, Ii zuka T, Shi ba T, Kanamori T, Yudasaka M, Ii j i ma S, Yokoyama A
    • Journal Title

      Nanotechnol ogy

      Volume: 22 Pages: 065102

    • Peer Reviewed
  • [Journal Article] Mai ntenance of hemi round col oni es and undi f f erent i ated state of mouse induced pluri potent stem cells on carbon nanotube- coated di shes2011

    • Author(s)
      Akasaka T, Yokoyama A, Mat suoka M, Hashi moto T, Wat ari F
    • Journal Title

      Carbon

      Volume: 49 Pages: 2287-2299

    • Peer Reviewed
  • [Presentation] Functionalization of carbon nanotubes by fibroblast growth factor2012

    • Author(s)
      Hirata E
    • Organizer
      The 2 sympojium of carbon nanoforms
    • Place of Presentation
      産総研(茨城県)
    • Year and Date
      2012-07-17
  • [Presentation] 補綴領域におけるナノテクノロジーの展望2011

    • Author(s)
      横山敦郎
    • Organizer
      日本補綴歯科学会東北・北海道、関越、東関東合同支部会
    • Place of Presentation
      日新潟県歯科医師会館(新潟)
    • Year and Date
      2011-09-24
  • [Presentation] ナノバイオマテリアルの開発と評価における医工連携日本補綴歯科学会2010

    • Author(s)
      横山敦郎
    • Organizer
      第119回学術大会
    • Place of Presentation
      東京ビッグサイト(東京)
    • Year and Date
      2010-06-13
  • [Book] ナノ材料のリスク評価と安全性対策2010

    • Total Pages
      29-34
    • Publisher
      フロンティア

URL: 

Published: 2014-08-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi