Development of bio-imaging technology using cell surface-like monolayer membrane

2012 Fiscal Year Final Research Report

• Project/Area Number: 22500417
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Biomedical engineering/Biological material science
• Research Institution: Kansai University
• Principal Investigator: FURUIKE Tetsuya 関西大学, 化学生命工学部, 准教授 (10360942)
• Project Period (FY): 2010 – 2012
• Keywords: シクロデキストリン / 両親媒性化合物 / 単分子膜 / 糖鎖クラスター効果 / バイオイメージング

Research Abstract

As a part of the development of glycoclustered device, we focused on cyclodextrin (CD) having the rigid and symmetrical structure. The synthetic method for the sugar-binding type of CD amphiphiles (GlycoCD amphiphiles), having bioactive sugars and long-chain fatty acids onto the CD, is established. The formation behavior of monolayers which is a two-dimensional molecular assembly is discussed by the use of the GlycoCD amphiphiles.

Research Products

• [Journal Article] Methods of N-acetylated chitosan scaffolds and its in-vitro biodegradation by lysozyme (2012)
  • Author(s): T. Han, N. Nwe, T. Furuike, S. Tokura, H. Tamura
  • Journal Title: J. Biomedical Science and Engineering Volume: 5 Pages: 15-23
  • DOI: DOI:10.4236/jbise.2012.51003
  • Peer Reviewed
• [Journal Article] Chitin scaffolds in tissue engineering (2011)
  • Author(s): R. Jayakumar, K.P. Krishna, S. Srinivasan, S.V. Nair, T. Furuike, H. Tamura
  • Journal Title: Int. J. Mol. Sci. Volume: 12 Pages: 1876-1887
  • DOI: DOI:10.3990/ijms.12031876
  • Peer Reviewed
• [Journal Article] Preparation and characterization of chitosan-gelatin/ nano hydroxyapatite composite scaffolds for tissue engineering applications (2010)
  • Author(s): M. Peter, N. Ganesh, N. Selvamurugan, S.V. Nair, T. Furuike, H. Tamura, R. Jayakumar
  • Journal Title: Carbohydr. Polymers Volume: 80 Pages: 687-694
  • DOI: DOI:10.1016/j.carbpol.2009.11.050
  • Peer Reviewed
• [Presentation] イオン液体を用いた糖鎖合成法 (2013)
  • Author(s): 平井智也、田村裕、古池哲也
  • Organizer: 第17回先端科学技術シンポジウム
  • Place of Presentation: 大阪
  • Year and Date: 20130129-30
• [Presentation] シクロデキストリンを用いた両親媒性化合物の合成と機能 (2012)
  • Author(s): 岡村俊佑,田村裕, 古池哲也
  • Organizer: 第31回日本糖質学会年会
  • Place of Presentation: 鹿児島
  • Year and Date: 20120917-21
• [Presentation] マイクロ波を用いたオリゴ糖の化学修飾 (2012)
  • Author(s): 平井智也、田村裕、古池哲也
  • Organizer: 第31回日本糖質学会年会
  • Place of Presentation: 鹿児島
  • Year and Date: 20120917-21
• [Presentation] Chemo- enzymatic synthesis of glycoclustered cyclodextrins (GlycoCDs) (2012)
  • Author(s): T. Furuike, H. Tamura
  • Organizer: The 7th International Symposium in Science and Technology: Bridging Research for Advancement of Knowledge and Technology
  • Place of Presentation: Penang, Malaysia
  • Year and Date: 20120830-31
• [Presentation] イオン液体を用いた糖鎖合成法 (2012)
  • Author(s): 平井智也、田村裕、古池哲也
  • Organizer: 第26回キチン・キトサンシンポジウム
  • Place of Presentation: 札幌
  • Year and Date: 20120712-13
• [Presentation] 化学-酵素合成法を用いた人工複合糖質化合物の合成研究 (2012)
  • Author(s): 古池哲也
  • Organizer: 第16回先端科学技術シンポジウム
  • Place of Presentation: 大阪
  • Year and Date: 20120123-24
• [Presentation] Development of Carbohydrate Synthesis Using Ionic Liquids (2012)
  • Author(s): S. Okamura, T. Hirai, T. Furuike, H. Tamura
  • Organizer: The 3rd Research Symposium on Petrochemical and Materials Technology and The 18th PPC Symposium on Petroleum, Petrochemicals, and Polymers
  • Place of Presentation: Bangkok, Thailand
  • Year and Date: 2012-04-24
• [Presentation] 細菌表層由来オリゴ糖の合成 (2011)
  • Author(s): 松村勲、田村裕、古池哲也
  • Organizer: 第25回キチン・キトサンシンポジウム
  • Place of Presentation: 奈良
  • Year and Date: 20110830-31
• [Presentation] 固相合成法を用いたオリゴ糖の合成 (2011)
  • Author(s): 箕輪英之、田村裕、古池哲也
  • Organizer: 第25回キチン・キトサンシンポジウム
  • Place of Presentation: 奈良
  • Year and Date: 20110830-31
• [Presentation] Modification and glycosylation of carbohydrates in ionic liquids (2011)
  • Author(s): T. Hirai, H. Tamura, T. Furuike
  • Organizer: 6th International Symposium in Science and Technology at Kansai University 2011, Collaboration between Asian countries in materials, chemistry, life science, information technology, civil engineering and ecological interface design
  • Place of Presentation: Osaka, Japan
  • Year and Date: 20110824-26
• [Presentation] Preparation and characterization of chitosan- coated PLA fiber and braided rope (2011)
  • Author(s): T. Furuike, D. Komoto, H. Nagahama, S. Maki, H. Seo, H. Tamura
  • Organizer: The 9th Asia-Pacific Chitin and Chitosan Symposium
  • Place of Presentation: Nha Trang, Vietnam
  • Year and Date: 20110803-06
• [Presentation] イオン液体を用いた糖鎖合成法の開発 (2011)
  • Author(s): 平井智也、田村裕、古池哲也
  • Organizer: 第30回日本糖質学会年会
  • Place of Presentation: 長岡
  • Year and Date: 20110711-13
• [Presentation] Chemical and enzymatic synthesis of cyclodextrin- scaffolded glycoclusters (GlycoCDs) (2010)
  • Author(s): T. Furuike, H. Tamura
  • Organizer: Pacifichem2010
  • Place of Presentation: Honolulu, USA
  • Year and Date: 20101215-20
• [Presentation] キチン・キトサン関連オリゴ糖の合成 (2010)
  • Author(s): 森川嵩士、田村裕、古池哲也
  • Organizer: 第24回キチン・キトサンシンポジウム
  • Place of Presentation: 東京
  • Year and Date: 20100713-14
• [Remarks]
  • URL: http://www.chemmater.kansai-u.ac.jp/biofunc/