Age-related augmentation of blood pressure response to exercise

2012 Fiscal Year Final Research Report

• Project/Area Number: 22500496
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: National Institute of Advanced Industrial Science and Technology
• Principal Investigator: KOMINE Hidehiko 独立行政法人産業技術総合研究所, ヒューマンライフテクノロジー研究部門, 主任研究員 (10392614)
• Co-Investigator(Kenkyū-buntansha): SUGAWARA Jun 独立行政法人 産業技術総合研究所, ヒューマンライフテクノロジー研究部門, 主任研究員 (00357261) ; YOKOI Takashi 独立行政法人 産業技術総合研究所, ヒューマンライフテクノロジー研究部門, 副研究部門長 (80192805)
• Project Period (FY): 2010 – 2012
• Keywords: 理学療法学 / 動脈血圧反射 / 心拍数 / 血圧

Research Abstract

The purpose of this study was to clarify the underling mechanism(s) that are responsible for the age-related augmentation of blood pressure response during exercise. To clarify the mechanism(s), we focused on the arterial baroreflex. We thus developed a d

Research Products

• [Journal Article] Non-invasive assessment of arterial stiffness using oscillometric blood pressure measurement (2012)
  • Author(s): Komine H, Asai Y, Yokoi T, Yoshizawa M
  • Journal Title: Biomed Eng Online Volume: 10 Pages: 11-6
  • DOI: doi:10.1186/1475-925X-11-6
  • Peer Reviewed
• [Journal Article] Impact of Chronic Exercise Training on the Blood Pressure Response to Orthostatic Stimulation (2012)
  • Author(s): Sugawara J, Komine H, Miyazawa T, Imai T, Fisher JP, Ogoh S
  • Journal Title: J Appl Physiol Volume: 112(11):1891-6
  • Peer Reviewed
• [Journal Article] Modulation of radial blood flow during Braille character discrimination task (2012)
  • Author(s): Murata J, Matsukawa K, Komine H, Tsuchimochi H
  • Journal Title: Acta Physiol Hung Volume: 99(1):25-32
  • Peer Reviewed
• [Journal Article] Effects of exercise training on the baroreflex control of arterial blood pressure (2012)
  • Author(s): Komine H
  • Journal Title: J Physiol Sci Volume: 62 (Suppl 1) Pages: S36
  • Peer Reviewed
• [Journal Article] High circulating levels of oxidized LDL in strength-trained athletes (2011)
  • Author(s): Choi Y, Maeda S, Yoshizawa M, Tanabe K, Miyaki A, Tanabe Y, Komine H, Hirayama A, Shiraki H, Ajisaka R
  • Journal Title: Journal of Exercise Nutrition & Biochemistry Volume: 15(2): 105-110
  • Peer Reviewed
• [Journal Article] The effects of regular endurance exercise on IL-6 and the sympathetic nervous system (2011)
  • Author(s): Komine H, Yoshizawa M, Maeda S, Shimojo N, Takai Y, Akazawa N, and Yokoi T
  • Journal Title: FASEB J Volume: 25 Pages: 1056.5
  • Peer Reviewed
• [Journal Article] Circulating endothelial progenitor cells in strength-trained men (2011)
  • Author(s): Yoshizawa M, Maeda S, Choi Youngju, Shimojo N, and Komine H
  • Journal Title: FASEB J Volume: 25 Pages: 1056.1
  • Peer Reviewed
• [Journal Article] The effects of regular endurance exercise on IL-6 and the sympathetic nervous system (2011)
  • Author(s): Komine H, Yoshizawa M, Maeda S, Shimojo N, Takai Y, Akazawa N, and Yokoi T
  • Journal Title: J Physiol Sci Volume: 61 (Suppl 1) Pages: S195
  • Peer Reviewed
• [Journal Article] Racial defferences in relation between carotid and radial augmentation index (2010)
  • Author(s): Sugawara J, Komine H, Yoshizawa M, Tarumi T, Maeda S, Tanaka H
  • Journal Title: Artery Res Volume: 4(1): 15-15
  • Peer Reviewed
• [Journal Article] Effects of regular endurance exercise on brachial blood flow response to mental stress (2010)
  • Author(s): Komine H, Takai Y, Akazawa N, Maeda S, Yoshizawa M, Sugawara J, and Yokoi T
  • Journal Title: FASEB J Volume: 24 Pages: 804.5
  • Peer Reviewed
• [Journal Article] Sort- and longterm effects of exercise on the arterial baroreflexes (2010)
  • Author(s): Komine Hand Matsukawa K
  • Journal Title: J Physiol Sci Volume: 60 (Suppl 1) Pages: S49
  • Peer Reviewed
• [Presentation] A method of evaluating the aortic baroreflex in human (2013)
  • Author(s): Komine H、 YoshizawaM、Miyazawa T
  • Organizer: 第90回日本生理学会
  • Place of Presentation: タワーホール船堀(東京)
  • Year and Date: 2013-03-29
• [Presentation] 動脈血圧反射受容器の刺激を利用した血圧調節機能評価とその応用 (2013)
  • Author(s): 小峰 秀彦
  • Organizer: 日本機械学会 第25回バイオエンジニアリング講演会
  • Place of Presentation: 産業技術総合研究所(茨城)
  • Year and Date: 2013-01-11
• [Presentation] 上腕で測る血管指標 (2012)
  • Author(s): 小峰 秀彦
  • Organizer: 第37回日本運動療法学会
  • Place of Presentation: 鷹産業プラザ(東京)
  • Year and Date: 2012-06-24
• [Presentation] Effects of exercise training on the baroreflex control of arterial blood pressure (2012)
  • Author(s): Komine H
  • Organizer: 第89回日本生理学会
  • Place of Presentation: 松本文化会館(長野)
  • Year and Date: 2012-03-30
• [Presentation] 動脈硬化を診る意義を再考する (2011)
  • Author(s): 小峰秀彦
  • Organizer: 第11回日本AS学会
  • Place of Presentation: ルークホール(東京)
  • Year and Date: 2011-10-01
• [Presentation] 3 週間の下肢免荷が足関節底屈運動時の膝窩動脈血流応答に与える影響 (2011)
  • Author(s): 峰 秀彦、吉澤睦子、赤澤暢彦、横井 孝志
  • Organizer: 第46回日本理学療法学術大会
  • Place of Presentation: シーガイアコンベンションセンター(宮崎)
  • Year and Date: 2011-05-29
• [Presentation] The effects of regular endurance exercise on IL-6 and the sympathetic nervous system (2011)
  • Author(s): Komine H, Yoshizawa M, Maeda S, Shimojo N, Takai Y, Akazawa N, and Yokoi T
  • Organizer: Experimental Biology
  • Place of Presentation: Washigton Convention Center (USA)
  • Year and Date: 2011-04-12
• [Presentation] Circulating endothelial progenitor cells in strength-trained men (2011)
  • Author(s): Yoshizawa M, Maeda S, Choi Youngju, Shimojo N, and Komine H
  • Organizer: Experimental Biology
  • Place of Presentation: Washigton Convention Center (USA)
  • Year and Date: 2011-04-12
• [Presentation] The effects of regular endurance exercise on IL-6 and the autonomic nervous system (2011)
  • Author(s): Komine H, Yoshizawa M, Maeda S, Shimojo N, Takai Y, Akazawa N, and Yokoi T
  • Organizer: 第88回日本生理学会
  • Place of Presentation: パシフィコ横浜(横浜)
  • Year and Date: 2011-03-29
• [Presentation] 血圧計を応用した動脈硬化測定装置の開発 (2010)
  • Author(s): 小峰秀彦
  • Organizer: 第10回日本AS学会
  • Place of Presentation: ルークホール(東京)
  • Year and Date: 2010-10-23
• [Presentation] Short- and longterm effects of exercise on the arterial baroreflexes (2010)
  • Author(s): Komine H, Matsukawa K
  • Organizer: 第87回日本生理学会
  • Place of Presentation: 盛岡市民文化ホール(岩手)
  • Year and Date: 2010-05-20
• [Presentation] Effects of regular endurance exercise on brachial blood flow response to mental stress (2010)
  • Author(s): Komine H, Takai Y, Akazawa N, Maeda S, Yoshizawa M, Sugawara J, and Yokoi T
  • Organizer: Experimental Biology
  • Place of Presentation: Anaheim Convention Center (USA)
  • Year and Date: 2010-04-26
• [Book] 運動時の心臓自律神経活動調節, In: 身体運動と呼吸・循環機能 (2012)
  • Author(s): 小峰秀彦,松川寛二
  • Total Pages: 211-217
  • Publisher: 真興交易(株)医書出版部
• [Book] セントラルコマンドと循環調節. In:運動生理学のニューエビデンス (2010)
  • Author(s): 小峰秀彦, 宮村実晴
  • Total Pages: 285-291
  • Publisher: 真興交易(株)医書出版部
• [Book] 循環器
  • Author(s): 小峰秀彦
  • Publisher: 人間工学ハンドブック(印刷中)