2012 Fiscal Year Final Research Report
Development of nano-scale layered structure for sensitive proteomics
| Project/Area Number |
22550084
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Analytical chemistry
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| Research Institution | Tokyo University of Technology |
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Principal Investigator |
YANO Kazuyoshi 東京工科大学, 医療保健学部, 教授 (40262109)
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| Co-Investigator(Renkei-kenkyūsha) |
AKIMOTO Takuo 東京工科大学, 応用生物学部, 准教授 (90367194)
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| Project Period (FY) |
2010 – 2012
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| Keywords | プロテオミクス / プラズマ重合 / 分析化学 / 薄膜 / 蛍光 |
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| Research Abstract |
Nano-scale layered structure composed of silver and plasma-polymerized layers was built up on the glass substrate. Immunoassay on the substrate revealed that the fluorescence intensity was enhanced about 8-fold compared with that obtained by unmodified substrate. Furthermore, the same effect could be achieved when the nano-scale layered structure was fabricated on the 96-well microtiter plate.
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[Journal Article] Fluorescence immunoassay using an optical fiber for determination of Dermatophagoides farinae (Der f 1)2011
Author(s)
K. Miyajima, G. Itabashi, T. Koshida, K. Tamari, D. Takahashi, T. Arakawa, H. Kudo, H. Saito, K. Yano, K. Shiba, K. Mitsubayashi
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Journal Title
Environmental Monitoring and Assessment
Volume: 182
Pages: 233-241
Peer Reviewed
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