2012 Fiscal Year Final Research Report
Regulation in the dimerization of ribosome during sporulation inBacillus subtilis
| Project/Area Number |
22570005
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Genetics/Genome dynamics
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| Research Institution | Rikkyo University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2012
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| Keywords | 分子遺伝 |
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| Research Abstract |
We found that more than half of the 70S ribosome were inactivated and then dimerized by the hibernation promoting factor, Hpf (YvyD) in the early stage of sporulation. The rRNA of the dimer of 70S ribosome was attacked first and finally the dimer ribosome was degraded in the late stage of sporulation. The hpf gene is actively transcribed from the promoter which is recognized by 〓H at the onset of the sporulation.
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[Journal Article] Single mutations introduced in the essential ribosomal protein L3 and S10 cause a sporulation defect in Bacillus subtilis.2013
Author(s)
Genki Akanuma, Shota Suzuki, Koichi Yano, Hideaki Nanamiya, Yousuke Natori, Namba Eri, Kazuya Watanabe, Kazumi Tagami, Takuya Takeda, Yuka Iizuka, Ako Kobayashi, Morio Ishizuka, Hirofumi Yoshikawa, and Fujio Kawamura.
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Journal Title
J. Gen. Appl. Microbiol.
Volume: 59
Pages: 106-117
Peer Reviewed
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[Journal Article] Expression of a small (p)ppGpp synthetase, YwaC, in the (p)ppGpp0 mutant of Bacillus subtilis triggersYvyD-dependent dimerization of ribosome.2012
Author(s)
Kazumi Tagami, Hideaki Nanamiya, Yuka Kazo, Marie Maehashi, Shota Suzuki, Eri Namba, Masahiro Hoshiya, Ryo Hanai, Yuzuru Tozawa, takuya Morimoto, Naotake Ogasawara,Yasushi Kageyama, Katsutoshi Ara, Katsuya Ozaki, Masaki Yoshida, Haruko Kuroiwa, Tsuneyoshi Kuroiwa, Yoshiaki Ohashi, and Fujio Kawamura.
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Journal Title
MicrobiologyOpen
Volume: 1
Pages: 115-134
DOI
Peer Reviewed
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