2012 Fiscal Year Final Research Report
Evolution of genetic regulatory networks through amplification and transposition of transposons
| Project/Area Number |
22570212
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Evolutionary biology
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| Research Institution | Hiroshima University |
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Principal Investigator |
HIKOSAKA Akira 広島大学, 大学院・総合科学研究科, 助教 (30263635)
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| Co-Investigator(Kenkyū-buntansha) |
KAWAHARA Akira 広島大学, 大学院・総合科学研究科, 教授 (50112157)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 遺伝子進化 / トランスポゾン / ツメガエル / ゲノム進化 / MITE / 自然選択 / 遺伝子発現調節 |
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| Research Abstract |
We studied the possibility that some transposons whose transposition activities have been retained for a long time in Xenopushave been involved in the evolution of genetic regulatory network. We developed a new strategy to find and classify the T2-MITE transposon family and searched the Xenoousgenomes for T2-MITEs. In addition, we analyzed insertion loci of such transposons and gene expression patterns of neighbor genes and found T2-MITE subfamilies whose transposition and amplification might have driven the evolution of genetic regulatory network of Xenopus.
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