2012 Fiscal Year Final Research Report
Characterization of a novel tripartite aromatic acids transporter, and its application for the production of industrially valuable metabolites
| Project/Area Number |
22580077
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied microbiology
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| Research Institution | Nagaoka University of Technology |
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Principal Investigator |
MASAI Eiji 長岡技術科学大学, 工学部, 教授 (20272867)
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| Project Period (FY) |
2010 – 2012
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| Keywords | フタル酸類 / テレフタル酸 / Comamonas属細菌 / 基質取り込み / 有用物質生産 / 生分解性ポリマー |
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| Research Abstract |
This study identified a novel type of aromatic acids transporter involved in terephthalate(TPA)uptake by Comamonas sp. strain E6. The TPA transporter is similar to the tripartite tricarboxylate transporter(TTT), and consists of the TpiA-TpiB membrane components and TPA-binding TphC. TPA uptake by E6 cells was completely inhibited by a protonophore, indicating that the TPA uptake system requires a proton motive force.
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