2012 Fiscal Year Final Research Report
Alcohol metabolism and its potential role of causing fatty liver in ruminants
| Project/Area Number |
22580310
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Zootechnical science/Grassland science
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| Research Institution | Hiroshima University |
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Principal Investigator |
TANIGUCHI Kohzo 広島大学, 大学院・生物圏科学研究科, 教授 (30093777)
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| Co-Investigator(Kenkyū-buntansha) |
OBITSU Taketo 広島大学, 生物圏科学研究科, 准教授 (30194632)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 反芻家畜 / 脂肪肝 / エタノール / 肝臓 / 脂質代謝 |
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| Research Abstract |
Effects of alcohol consumption on carbohydrate and lipid metabolism in ruminants were investigated by determining the changes of plasma concentrations and net fluxes by splanchnic tissues of metabolites with ruminal ethanol infusion in sheep. Ruminal ethanol infusion decreased plasma glucose concentration, increased plasma triglyceride concentration and net hepatic release of triglyceride in sheep. These results indicate that ethanol has a potential role of facilitatinghepatic lipid synthesis in ruminants.
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