2012 Fiscal Year Final Research Report
DEVELOPMENT OF NOVEL NITROGEN-CONTAINING 1,3-DIPOLARS
| Project/Area Number |
22590017
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Chemical pharmacy
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| Research Institution | Showa Pharmaceutical University |
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Principal Investigator |
TAMURA Osamu 昭和薬科大学, 薬学部, 教授 (30257141)
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| Project Period (FY) |
2010 – 2012
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| Keywords | ヘテロ環化学 |
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| Research Abstract |
A cytosolic protein, CERT, is known to mediate the transport of ceramide from the endoplasmic reticulum to the Golgi apparatus. Synthesis of syn-HPA-12, the selective inhibitor of CERT, was accomplished by using cis-selective cycloaddition reaction of C-a
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Research Products
(9 results)
