2012 Fiscal Year Final Research Report
The mechanism of hypotension by renin-angiotensin system
| Project/Area Number |
22590093
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biological pharmacy
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| Research Institution | Kobe Gakuin University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
OKAMOTO Hiroshi 神戸学院大学, 薬学部, 教授 (00028870)
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| Project Period (FY) |
2010 – 2012
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| Keywords | Rho キナーゼ / アンジオテンシン |
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| Research Abstract |
Vasotone plays an important role in the development of hypertension. In these studies we showed that cell acidification induces the vasolelaxation through production of NO which is vasolelaxation factor. On the other hand, inhibition of the protein tyrosine phosphatases and hypertonic stress induce the vasoconstriction.
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[Journal Article] Boron neutron capture therapy for clear cell sarcoma (CCS): biodistribution study of p-borono-L- phenylalanine in CCS-bearinganimal models.2011
Author(s)
Andoh T, Fujimoto T, Sudo T, Fujita I, Imabori M, Moritake H, Sugimoto T, Sakuma Y, Takeuchi T, Kawabata S, Kirihata M, Akisue T, Yayama K, Kurosaka M, Miyatake S, Fukumori Y, Ichikawa H.
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Journal Title
Appl Radiat Isot.
Volume: 69(12)
Pages: 1721-4
Peer Reviewed
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