2012 Fiscal Year Final Research Report
Disease control based on analysis of cutaneous microbiota in patients with psoriais
| Project/Area Number |
22590150
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Medical pharmacy
|
|---|
| Research Institution | Meiji Pharmaceutical University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2010 – 2012
|
| Keywords | 尋常性乾癬 / 増悪因子 / 皮膚微生物叢 / 疾患制御 |
|---|
| Research Abstract |
Psoriasis vulgaris (PS) is chronic skin disease with many scales. We focused on skin microbiota of the patients with PS as one of an exacerbating factor. Comprehensive analysis of skin microbiota by pyrosequencing assay revealed that patients’ microbiota was formed a specific microbiota compared with other skin diseases. The microbiota induced Th1-type cytokine and also were susceptible with cephem antibiotics. Our findings suggests that control of skin microbiota enable disease control of PS.
|
Research Products
(58 results)
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
[Book] In Molecular Detection of Human Fungal Pathogens, edited by Liu D2011
Author(s)
Sugita T, Tajima M, Tsubuku H, Miyamoto M, Zhang E, Tsuboi R, Takashima M, Ishibashi Y, Nishikawa A, Chapter 73 Malassezia
Total Pages
631-638
Publisher
CRC Press, New York
-
-
[Book] Epidemiology of Malassezia-related skin disease,In Malassezia and the Skin : Science and ClincialPractice, edited by2010
Author(s)
Sugita T, Boekhout T, Velegraki A,Guillot J, Hadina S, Cabanes J, Chapter 3
Total Pages
65-119
Publisher
Boekhout T, Kellemann G,Mayser P and Velegraki A
