2012 Fiscal Year Final Research Report
The confirmation of HTLV-1 associated Hepatitis
| Project/Area Number |
22590324
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Human pathology
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| Research Institution | Kurume University |
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Principal Investigator |
NIINO Daisuke 久留米大学, 医学部, 准教授 (20426563)
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| Co-Investigator(Kenkyū-buntansha) |
OHSHIMA Koichi 久留米大学, 医学部, 教授 (50203766)
SUGITA Yasuo 久留米大学, 医学部, 教授 (80216316)
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| Project Period (FY) |
2010 – 2012
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| Keywords | ウイルス / 病理学 / ATLL / HTLV-1 / 肝炎 |
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| Research Abstract |
We reported four ATLL patients who presented with fulminant hepatitis and analyzed those cases immunohistochemically. Next, we used HBZ gene in situ hybridization (HBZ-ISH) for detection of the HBZ gene in ATLL cell line and ATLL cases. This method is convenient and can be useful for the histological diagnosis of ATLL and HTLV-1-related diseases.
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