2012 Fiscal Year Final Research Report
Analysis of the skin cancer induced by ultraviolet
| Project/Area Number |
22590558
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Hygiene
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| Research Institution | Chubu University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KATO Masashi 名古屋大学, 医学部, 教授 (10281073)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 皮膚ガン / 紫外線 / 悪性黒色腫 |
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| Research Abstract |
We analyzed the down-regulation gene with tumor progression in melanoma. UV radiation down-regulates expression of the gene in murine benign tumor. Down-regulation of the gene was observed with tumor progression in human melanoma. Expression of the gene in melanoma decreased cell growth and invasive ability. These results suggested that the gene may prevent progression of melanoma.
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