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2012 Fiscal Year Final Research Report

The population based study of the predictive value of measurement of urinary albumin excretion by the HPLC method on the incidences of cardiovascular diseases and renal diseases.

Research Project

  • PDF
Project/Area Number 22590576
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Public health/Health science
Research InstitutionAkita University

Principal Investigator

NARITA Takuma  秋田大学, 大学院・医学系研究科, 准教授 (70282168)

Co-Investigator(Kenkyū-buntansha) FUJITA Hiroki  秋田大学, 医学部, 講師 (30333933)
Project Period (FY) 2010 – 2012
Keywords疫学
Research Abstract

The objectives of this study are 1) to test the efficacy of measurement of urinary albumin excretion by the novel HPLC method for predicting future development of diabetic nephropathy in diabetic patients without nephropathy and cardiovascular diseases in general population. We have established the cohort of approximately 100 diabetic outpatients without nephropathy and of approximately 1300 subjects who participated in annual health examination at Kita-akita city. Measurement and evaluation of urinary albumin excretions by HPLC and conventional method at the baseline had already done and we have found that the discrepancy of the urinary albumin values between HPLC method and conventional one. Also, in the general population of Kita-akita city, we found that approximately one fifth of people have chronic kidney disease, that is the indicator of high risk of future development of renal failure and cardiovascular diseases. We will continue prospective observation of this cohort regarding the development of cardiovascular diseases.

  • Research Products

    (4 results)

All 2013 2012 Other

All Presentation (3 results) Remarks (1 results)

  • [Presentation] 一般住民健診受診正常アルブミン尿糖尿病・高血圧患者で、HPLC法尿アルブミンは免疫法に比し尿細管障害をより反映する2013

    • Author(s)
      成田琢磨, 他
    • Organizer
      第56回日本糖尿病学会年次学術集会(平成25年)
    • Place of Presentation
      熊本市
    • Year and Date
      2013-05-17
  • [Presentation] 秋田県北秋田市における尿アルブミン、eGFRを指標とした慢性腎臓病(CKD)の有病率2012

    • Author(s)
      成田琢磨, 他
    • Organizer
      第23回日本老年医学会東北地方会
    • Place of Presentation
      秋田市
    • Year and Date
      2012-10-13
  • [Presentation] 2型糖尿病患者の正常アルブミン尿範囲内での尿アルブミン値は尿中8-OH-dGと相関する2012

    • Author(s)
      成田琢磨, 他
    • Organizer
      第55回日本糖尿病学会年次学術集会(平成24年)
    • Place of Presentation
      横浜市
    • Year and Date
      2012-05-19
  • [Remarks] 論文化でき次第、当施設のホームページ(内分泌・代謝・老年内科学講座)に掲載する

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Published: 2014-08-29  

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