2012 Fiscal Year Final Research Report
Effects of renal function on physical function, functional capacity of ADL, and quality of life in Japanese pre-frail elderly by intervention study
Project/Area Number |
22590578
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Public health/Health science
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Research Institution | University of Tsukuba |
Principal Investigator |
OKUNO Junko 筑波大学, 医学医療系, 研究員 (50360342)
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Co-Investigator(Kenkyū-buntansha) |
TOMURA Shigeo 浦和大学, 総合福祉学部, 教授 (60100955)
YANAGI Hisako 筑波大学, 医学医療系, 准教授 (10241811)
TANAKA Kiyoji 筑波大学, 体育系, 教授 (50163514)
OKURA Tomohiro 筑波大学, 体育系, 准教授 (60396611)
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Project Period (FY) |
2010 – 2012
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Keywords | 介護予防 / 25(OH)D濃度 / 体力 / 腎機能 / ビタミンD補充 |
Research Abstract |
The prevalence of eGFR < 60.0 ml/min/1.73m2was about 24.3%, and that of 25(OH)D < 75 nmol/L was 86.4%. Pre eGFR, pre 25(OH)D, and vitamin D supplementationwere significantly associated with improvement of mobility and muscle power. Our data suggest that assessment of renal function and maintaining appropriate vitamin D levels seem to be significant for independent living in the pre-frail elderly and higher 25(OH)D level might be needed for improvement of muscle strength than mobility; if possible, a 25(OH)D level greater than 67.5 nmol/L is preferable.
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[Presentation] Is vitamin D level for muscle strength improvement higher than that for mobility improvement for Japanese pre-frail elderly attending a nursing care prevention class? :Examination of alfacalcidol supplementation and renal function2011
Author(s)
Junko Okuno, Shigeo Tomura, Takako Fukasaku, Noriko Yabushita, Mi-Ji Kim, Tomohiro Okura, Kiyoji Tanaka, and Hisako Yanagi
Organizer
ASBMR, 2011 annual Meeting
Place of Presentation
San Diego convention Center, San Diego, California, US
Year and Date
20110916-20
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