2012 Fiscal Year Final Research Report
How far can the MLPA method and the DNA array method do the limit of a water chromosomal test in conquest
| Project/Area Number |
22591210
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Embryonic/Neonatal medicine
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| Research Institution | Kanazawa Medical University |
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Principal Investigator |
OZAKI Mamoru 金沢医科大学, 総合医学研究所, 助教 (50319068)
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| Co-Investigator(Kenkyū-buntansha) |
ISHIGAKI Yasuhito 金沢医科大学, 総合医学研究所, 准教授 (20232275)
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| Co-Investigator(Renkei-kenkyūsha) |
NIIDA Yo 金沢大学, 医学部, 准教授 (40293344)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 出生前診断 |
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| Research Abstract |
When the MLPA method really used it, We needed the reagent for 5 tests for normal control, and the reagent for 5 tests was necessary for one inspection. We did not change with the DNA array method for the cost. We were not able to obtain the DNA array method so as to have expected the inspection consent of the case in the late stage of the pregnancy that We expected. Consent was provided in the case that a marker chromosome (origin ignorance accessory chromosome) was recognized by amniotic diagnosis of the second pregnancytrimester, and the origin became clear in 3 cases.
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