2012 Fiscal Year Final Research Report
Evaluation of vascular permeability imaging using 3D-FLAIRMRI sequence
| Project/Area Number |
22591345
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Kumamoto University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
HIRAI Toshinori 熊本大学, 大学院・生命科学研究部, 准教授 (40274724)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 核磁気共鳴画像(MRI) |
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| Research Abstract |
3D FLAIR is an imaging method of MRI. The enhancing effect emergesby the contrast agent leaked into the cerebrospinal fluid and extravascular interstitialspaces, while the signal intensity of the flowing blood is strongly suppressed. Therefore,there is a possibility that 3D FLAIR can depict the vessel parts with vascular permeability.Our study revealed that the signal intensity of 3D FLAIR was reduced with blood flowvelocity of more than 0.25-0.5cm/sec and was stronger with contrast agent concentrationof less than 0.5mmol/L.
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