2013 Fiscal Year Final Research Report
Study on optimization by using functional images for low-risk and high-precision radiotherapy for lung cancer
| Project/Area Number |
22591387
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
NAKAMURA Katsumasa 九州大学, 大学病院, 准教授 (20284507)
ARIMURA Hidetaka 九州大学, 大学院医学研究院, 准教授 (20287353)
YOSHITAKE Tadamasa 九州大学, 大学院医学研究院, 講師 (40452750)
HONDA Hiroshi 九州大学, 大学院医学研究院, 教授 (90145433)
HATAKENAKA Masamitsu 札幌医科大学, 医学部, 教授 (40253413)
ABE Kouichirou 東京女子医科大学, 医学部, 准教授 (00380387)
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| Project Period (FY) |
2010-04-01 – 2014-03-31
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| Keywords | 肺癌 / 強度変調放射線治療 / 定位放射線治療 / 機能画像 |
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| Research Abstract |
In the high-precision radiotherapy (intensity modulated radiation therapy and stereotactic radiation therapy) for lung cancer patients, we quantitatively compared the dose distribution between the treatment plans optimized by using functional images and the treatment plans optimized by using anatomical images only. The optimization using functional images was considered to be useful in minimizing the decrease of pulmonary function, and this approach was thought to be more beneficial to the high-risk patients in particular. Furthermore, this functional-image-guided optimization was suggested to become more effective by using non-coplanar beams in addition to coplanar beams.
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Research Products
(34 results)
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[Journal Article] 肺癌の放射線治療2014
Author(s)
塩山善之, 中村和正, 佐々木智成, 大賀才路, 吉武忠正, 浅井佳央里, 寺嶋広太郎, 松本圭司, 松尾芳雄, 藪内英剛, 本田浩
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Journal Title
画像診断
Volume: 34(2)
Pages: 199-205
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[Journal Article] Clinical results of stereotactic body radiotherapy for Stage I small-cell lung cancer; a single institutional experience2013
Author(s)
Shioyama Y, Nakamura K, Sasaki T, Ohga S, Yoshitake T, Nonoshita T, Asai K, Terashima K, Matsumoto K, Hirata H, Honda H
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Journal Title
J Radiat Res
Volume: 54(1)
Pages: 108-112
Peer Reviewed
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[Journal Article] Association between EGFR-TKI Resistance and Efficacy of Radiotherapy for Brain Metastases from EGFR-mutant Lung Adenocarcinoma2013
Author(s)
Hirata H, Nakamura K, Kunitake N, Shioyama Y, Sasaki T, Ohga S, Nonoshita T, Yoshitake T, Asai K, Inoue K, Nagashima A, Ono M, Honda H
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Journal Title
Anticancer Res
Volume: 33(4)
Pages: 1649-1655
Peer Reviewed
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[Journal Article] Definitive Fractionated Re-irradiation for Local Recurrence Following Stereotactic Body Radiotherapy for Primary Lung Cancer2013
Author(s)
Yoshitake T, Shioyama Y, Nakamura K, Sasaki T, Ohga S, Shinoto M, Terashima K, Asai K, Matsumoto K, Hirata H, Honda H
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Journal Title
Anticancer Res
Volume: 33(12)
Pages: 5649-5653
Peer Reviewed
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[Journal Article] Phase II study of concurrent thoracic radiotherapy in combination with weekly paclitaxel plus carboplatin in locally advanced non-small cell lung cancer : LOGIK04012013
Author(s)
Takayama K, Inoue K, Tokunaga S, Matsumoto T, Oshima T, Kawasaki M,Imanaga T, Kuba M, Takeshita M, Harada T, Shioyama Y, Nakanishi Y
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Journal Title
Chemother Pharmacol
Volume: 72(6)
Pages: 1353-1359
Peer Reviewed
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[Journal Article] Radiation-Induced Rib Fractures After Hypofrationated Stereotactic Body Radiation Therapy : Risk Factors and Dose-Volume Relationship2012
Author(s)
Asai K, Shioyama Y, Nakamura K, Sasaki T, Ohga S, Nonoshita T, Yoshitake T, Ohnishi K, Terashima K, Matsumoto K, Hirata H, Honda H
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Journal Title
Int J Radiat Oncol Biol Phys
Volume: 84(3)
Pages: 768-773
Peer Reviewed
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[Journal Article] Acute cardiac impairment associated with concurrent chemoradiotherapy for esophageal cancer : Magnetic resonance evaluation2012
Author(s)
Hatakenaka M, Yonezawa M, Nonoshita T, Nakamura K, Yabuuchi H, Shioyama Y, Nagao M, Matsuo Y, Kamitani T, Higo T, Nishikawa K, Setoguchi T, Honda H
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Journal Title
Int J Radiat Oncol Biol Phys
Volume: 83(1)
Pages: e67-73
Peer Reviewed
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[Journal Article] A Case of Lung Cancer with Chest Wall Invasion Showed a Pathologically Complete response to PreoperativeThermo-chemo-radiothera py2011
Author(s)
Terashima K, Shioyama Y, Nomoto S, Ohga S, Nonoshita T, Yoshitake T, Ohnishi K, Asai K, Matsumoto K, Takayama K, Nakamura K, Terashima H, Honda H
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Journal Title
Thermal Medicine
Volume: 27
Pages: 25-30
Peer Reviewed
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[Journal Article] Clinical Results of Definitive Chemoradiotherapy for Patients With Synchronous Head and Neck Squamous Cell Carcinoma and Esophageal Cancer2011
Author(s)
Shinoto M, Shioyama Y, Sasaki T, Nakamura K, Ohura H, Toh Y, Higaki Y, Yamaguchi T, Ohnishi K, Atsumi K, Hirata H, Honda H
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Journal Title
Am J Clin Oncol
Volume: 34
Pages: 362-366
Peer Reviewed
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[Journal Article] Prediction of Local Failures with a Combination of Pretreatment Tumor Volume and Apparent Diffusion Coefficient in Patients Treated with Definitive Radiotherapy for Hypopharyngeal or Oropharyngeal Squamous Cell Carcinoma2011
Author(s)
Ohnishi K, Shioyama Y, Hatakenaka M, Nakamura K, Abe K, Yoshiura T, Ohga S, Nonoshita T, Yoshitake T, Nakashima T, Honda H
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Journal Title
J Radiat Res
Volume: 52
Pages: 522-530
Peer Reviewed
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[Journal Article] Apparent Diffusion Coefficient Calculated with Relatively High b-Values Correlates with Local Failure of Head and Neck Squamous Cell Carcinoma Treated with Radiotherapy2011
Author(s)
Hatakenaka M, Shioyama Y, Nakamura K, Yabuuchi H, Matsuo Y, Sunami S, Kamitani T, Yoshiura T, Nakashima T, Nishikawa K, Honda H
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Journal Title
Am J Neuroradiol
Volume: 32(10)
Pages: 1904-1910
Peer Reviewed
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