2012 Fiscal Year Final Research Report
Development of adaptive radiotherapy using preliminarily-contouredstrictures and cone-beam CT for daily setup
| Project/Area Number |
22591388
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Kumamoto University |
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Principal Investigator |
MURAKAMI Ryuji 熊本大学, 生命科学研究部, 教授 (90295147)
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| Co-Investigator(Renkei-kenkyūsha) |
HIRAI Toshinori 熊本大学, 生命科学研究部, 准教授 (40274724)
KATSURAGAWA Shigehiko 熊本大学, 生命科学研究部, 教授 (60021630)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 放射線治療学 / 放射線治療計画 / 画像融合 / コーンビーム CT |
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| Research Abstract |
We designed a preliminary-contouring system for “double reading”in the gross tumor volume (GTV) assessment. Although there was minor system error,considerable interobserver differences for GTV contouring persisted; our system can bea valuable method for the integration of GTV contouring. The differences in prescribeddoses based on cone-beam computed tomography (CBCT) for daily setup were less than 5%. The combination of the preliminary-contouring system and CBCT-derived dose calculationcan provide adaptive radiotherapy matching with anatomical changes at each fraction.
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[Journal Article] Histopathologicalchanges in parotid and submandibularglands of patients treated withpreoperative chemoradiation therapyfor oral cancer2012
Author(s)
Keiko Teshima1, Ryuji Murakami, RyojiYoshida, Hideki Nakayama, AkimitsuHiraki, Toshinori Hirai, Yuji Nakaguchi,Naoko Tsujita, Etsushi Tomitaka,Mitsuhiro Furusawa, Yasuyuki Yamashita,Masanori Shinohara
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Journal Title
J Radiat Res
Volume: 53(3)
Pages: 492-496
DOI
Peer Reviewed
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[Journal Article] FDG-PET/CT-basedGross Tumor Volume Contouring forRadiation Therapy Planning2012
Author(s)
Ryo Toya, Ryuji Murakami, KuniyukiTashiro, Morikatsu Yoshida, FumiSakamoto, Koichi Kawanaka, ShinyaShiraishi, Yuji Nakaguchi, NaokoTsujita, Natsuo Oya, Seiji Tomiguchi,Yasuyuki Yamashita
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Journal Title
J RadiatRes
Volume: 53(2)
Pages: 338-341
DOI
Peer Reviewed
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[Journal Article] Longitudinal Changes over 2 Years inParotid Glands of Patients Treated withPreoperative 30-Gy Irradiation for OralCancer2011
Author(s)
Etsushi Tomitaka, Ryuji Murakami, KeikoTeshima, Tomoko Nomura, Yuji Nakaguchi,Hideki Nakayama, Mika Kitajima,Toshinori Hirai, Yushi Araki, MasanoriShinohara, Yasuyuki Yamashita
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Journal Title
Jpn J Clin Oncol
Volume: 41(4)
Pages: 503-507
DOI
Peer Reviewed
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[Journal Article] PhaseII study of preoperative concurrentchemoradiation therapy with S-1 inpatients with T4 oral squamous cellcarcinoma2010
Author(s)
Tomoko Nomura, Ryuji Murakami, Ryo Toya,Keiko Teshima, Aya Nakahara, ToshinoriHirai, Akimitsu Hiraki, Hideki Nakayama,Yoshiyasu Yoshitake, Kazutoshi Ohta,Obayashi Takehisa, Yasuyuki Yamashita,Natsuo Oya, Masanori Shinohara
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Journal Title
Int J Radiat Oncol Biol Phys
Volume: 76(5)
Pages: 1347-1352
DOI
Peer Reviewed
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