2012 Fiscal Year Final Research Report
New approach of radiotherapy to non-cycling tumor stem cells by repair gene inhibition
| Project/Area Number |
22591391
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Keio University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KAWATA Tetsuya 慶應義塾大学, 医学部, 講師 (60234077)
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| Project Period (FY) |
2010 – 2012
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| Keywords | ATM / NBS1 / 修復抑制 / 染色体解析 / 静止期 |
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| Research Abstract |
Confluent normal fibroblast cells and non-cycling tumor cells were exposed to X-rays and chromosome aberrations were investigated in the first G2/M phase after exposure. Cells were subcultured 24 h with ATM and NBS1 inhibitor after exposure and chromosome
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