2012 Fiscal Year Final Research Report
Application of hemoglobin vesicles for lung transplantation
| Project/Area Number |
22591575
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Thoracic surgery
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| Research Institution | Keio University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
HORINOUCHI Hirohisa 慶應義塾大学, 医学部, 准教授 (60173647)
NOMORI Hiroaki 慶應義塾大学, 医学部, 教授 (90146613)
IZUMI Yotaro 慶應義塾大学, 医学部, 講師 (90245506)
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| Co-Investigator(Renkei-kenkyūsha) |
SAKAI Hiroshi 早稲田大学, 重点領域研究機構, 教授 (70318830)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 移植・再生医療 / 呼吸器外科 |
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| Research Abstract |
On a mouse pneumonectomy model, the infusion of hemoglobinvesicles compensated for 40% of blood loss caused by pneumonectomy, without interferingwith the recovery of mice from the operation. On a perfusion circuit with hemoglobinvesicles, donor lungs were
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