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2012 Fiscal Year Final Research Report

Effect of anesthetic agents on inhibitory or excitatory transmission in the substantia gelatinosa revealed by in vivo patch clamp recordings

Research Project

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Project/Area Number 22591736
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Anesthesiology/Resuscitation studies
Research InstitutionKyushu University

Principal Investigator

YAMAURA Ken  九州大学, 大学病院, 准教授 (70264041)

Co-Investigator(Kenkyū-buntansha) YAMAURA Ken  熊本保健科学大学, 生命科学研究科, 教授 (10140641)
SHIOKAWA Hiroaki  九州大学, 大学病院, 助教 (30572490)
KARASHIMA Yuji  九州大学, 大学病院, 助教 (80380434)
Project Period (FY) 2010 – 2012
Keywords疼痛管理学
Research Abstract

The patch clamp technique is a laboratory technique in electrophysiology that allows the study of single or multiple ion channels in cells. Using this method, transmission between neurons can be analyzed in detail. In this project, we observed the responses evoked by tactile stimulation in the spinal cord and analyzed the effect of remifentanil which is known as opioid on nociceptive transmission by invivo patch clamp recordings.

  • Research Products

    (3 results)

All 2012 2010

All Presentation (3 results)

  • [Presentation] Analysis of analgesic effect of propofol by in-vivo patch clamp recordings from the somatosensory cortex of rats2012

    • Author(s)
      塩川 浩輝、山浦 健、辛島 裕士、外須美夫
    • Organizer
      Annual Meeting of the American Society of Anesthesiologists
    • Place of Presentation
      米国、ワシントンD.C
    • Year and Date
      2012-10-14
  • [Presentation] Analysis of analgesic effect of propofol by in-vivo patch clamp recordings from the somatosensory cortex of rats2012

    • Author(s)
      塩川 浩輝、古賀 公平、山浦 健、辛島裕士、外 須美夫
    • Organizer
      European Society of Anesthesiology annual meeting, Euroanaesthesia 2012
    • Place of Presentation
      フランス、パリ
    • Year and Date
      2012-06-10
  • [Presentation] Differential NR2 Subunit Composition of NMDA receptors between Inhibitory and Ecxitatory Interneurons of the Mouse Spinal Dorsal Horn2010

    • Author(s)
      塩川 浩輝、Chi-Kun Tong、外 須美夫、Amy B. MacDermott
    • Organizer
      Annual Meeting of the American Society of Anesthesiologists
    • Place of Presentation
      米国、サンディエゴ
    • Year and Date
      2010-10-17

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Published: 2014-08-29  

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