2012 Fiscal Year Final Research Report
Development of novel diagnostic tool for male infertility using near-infrared spectroscopy
| Project/Area Number |
22591807
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Urology
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| Research Institution | Osaka University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
辻村 晃 大阪大学, 大学院・器官制御外科学, 泌尿器科 (40294053)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 男性不妊症 / 精液検査 / 精子 / 精巣 |
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| Research Abstract |
Non-obstructive azoospermia (NOA) is an vital condition of male infertility which presents no sperm in ejaculate. But 40% of NOA patients still maintainspermatogenesis in their testis and testicular sperm extraction combined with intracytoplasmic sperm injection is only the way to treat NOA patients. However it is actually difficult to predict successful sperm retrieval presurgically by previous diagnostic tools. We found near-infrared spectroscopic examination may predict existence of sperm in non-invasive condition. Further study will help us to predict successful outcome more accurately .
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[Journal Article] A single nucleotide polymorphism within the novel sex-linked testis-specific retrotransposed PGAM4 gene influences human male fertility2012
Author(s)
Okuda H, Tsujimura A, Irie S, Yamamoto K, Fukuhara S, Matsuoka Y, Takao T, Miyagawa Y, Nonomura N, Wada M, Tanaka H
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Journal Title
PLoS One
Volume: 7
Pages: e35195
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[Presentation] Clinical investigation of patients with ejaculatory dysfunction and male infertility2011
Author(s)
Yasushi Miyagawa, Tetsuya Takao, Hidenobu Okuda, Keisuke Yamamoto, Yasuhiro Matsuoka, Akira Tsujimura, Shingo Takada, Kiyomi Matsumiya, Yoshio Okamoto , Norio Nonomura
Organizer
The 13thBiennial Meeting of the Asia
Place of Presentation
Pacific Society for Sexual MedicineKaohsiung, Taiwan
Year and Date
2011-11-18
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