2012 Fiscal Year Final Research Report
Experimental study of suprachoroidal drug delivery
| Project/Area Number |
22591933
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Ophthalmology
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| Research Institution | University of Toyama |
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Principal Investigator |
HAYASHI Atsushi 富山大学, 大学院・医学薬学研究部(医学), 教授 (20283773)
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| Co-Investigator(Kenkyū-buntansha) |
MITARAI Keiichi 富山大学, 大学病院, 助教 (50527918)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 眼組織学 |
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| Research Abstract |
We designed a method to deliver drugs into the eye for a relatively long term by delivering collagen gel and steroid into the suprachoroidal space between the sclera and the choroid. We examined the injected collagen gel histologically. As results, we found the collagen gel disappeared from the suprachoroidal space by 3 months after injection. The intraocular concentrations of the steroid mixed with the collagen gel were not significantly different from those of the steroid only during 3 months.
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