2012 Fiscal Year Final Research Report
Research of pathophysiology of age-related macular degeneration using quantitative analysis of retinal photoreceptor and retinal pigment epithelial function
| Project/Area Number |
22591946
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Ophthalmology
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| Research Institution | Tokyo Women's Medical University (2012)
Fukushima Medical University (2010-2011) |
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Principal Investigator |
IIDA Tomohiro 東京女子医科大学, 医学部, 教授 (50241881)
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| Co-Investigator(Kenkyū-buntansha) |
SEKIRYU Tetsuju 福島県立医科大学, 医学部, 教授 (00216540)
MARUKO Ichiro 福島県立医科大学, 医学部, 講師 (10443871)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 加齢黄斑変性 / 眼底自発蛍光 / 定量化 |
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| Research Abstract |
We made a new filter (>555nm) to record green fundus autofluorescence (FAF) to remove the influence the crystalline lens condition and macular pigment. To quantify the intensity of FAF, we built in a fluorescent reference board into the scanning laser ophthalmoscope (SLO). However, the intensity of FAF varied depending on the grade of cataract. We added on another new correction system. The intensity of light on the retina was corrected by the ratio of infrared/green light. Infrared reference was built into the SLO for this aim.
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