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2013 Fiscal Year Final Research Report

Relationship of ECM superstructure and cytokine in the osteogenesis

Research Project

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Project/Area Number 22592038
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Morphological basic dentistry
Research InstitutionOkayama University

Principal Investigator

Kawai Mariko  岡山大学, 医歯(薬)学総合研究科, 助教 (40379839)

Co-Investigator(Kenkyū-buntansha) 十川 紀夫  岡山大学, 医歯(薬)学総合研究科, 准教授 (30236153)
Research Collaborator Neubueser Annette  Freiburug University, Dr. Prof.
herrmann David  Freiburug University, Dr.
Project Period (FY) 2010-04-01 – 2014-03-31
Keywords発生・分化 / 細胞外基質 / サイトカイン
Outline of Final Research Achievements

The superstructure of extracelluar matrix controls cytokine's activities. In this study, we tried to analyze how laminin super structure effects bone formation through the interaction fgf signaling. We made monoclonal antibodies for laminin super structure and applied them to in vitro and in vivo bone formation models. Our results might conclude that laminin super structure could control bone formation and calcification.

Free Research Field

医歯薬学

  • Research Products

    (1 results)

All 2013

All Presentation (1 results)

  • [Presentation] fgf conditional knock out mice derived chondrogenesis andosteogenesis in the cranial bone formation2013

    • Author(s)
      河井まりこ、山本敏男
    • Organizer
      第55回歯科基礎医学会総会•学術集会
    • Place of Presentation
      岡山
    • Year and Date
      20130920-22

URL: 

Published: 2015-07-16   Modified: 2022-01-27  

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