2012 Fiscal Year Final Research Report
The effect of gradient FGF-2 on one-wall intrabony defect of periodontal tissue
| Project/Area Number |
22592182
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | Osaka University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
YAMADA Satoru 大阪大学, 歯学部附属病院, 講師 (40359849)
HASHIKAWA Tomoko 大阪大学, 大学院・歯学研究科, 助教 (00362682)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 再生歯学 |
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| Research Abstract |
The present study showed that FGF-2 activated MPDL-22 proliferative reaction and cell migration and that the FGF-2-induced activity of cell migration was dependent on PI3K and akt pathway. Hyaluronan was also associated with the FGF-2-activated cell migration. FGF-2 enhanced the regenerative effect on periodontal tissue induced by ADSC
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[Presentation] EVALUATION OF PERIODONTAL TISSUE REGENERATION BY TRANSPLANTATION OF ADIPOSE-TISSUE DERIVED STEM CELLS2013
Author(s)
Keigo Sawada, Masahide Takedachi, Masao Ozasa, Tomoaki Iwayama, Takenori Nozaki,Takushi Tauchi, Koji Miki, Mitsuyoshi Iyama, Jun Anzai, Toshie Nagayasu, Akio
Organizer
The 6th Pan Pacific Symposium on Stem Cells and Cancer Research (PPSSC) 2nd Meeting of the International Association for Dental Research - Asia Pacific Region
Year and Date
2013-04-13
